1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		S	V	Y	D	A	A	A	Q	L	T	A	D	V	K	K	D	L	R	D	S	W	K	V	I	G	S	D	K	K	G	N	G	V	A	L	M	T	T	L	F	A	D	N	Q	E	T	I	G	Y	F	K	R	L	G	N	V	S	Q	G	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																																													?	?	?	?	?	?	?
Disorder confidence
Conserved Domain info																																						•										•			•	•
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	N	D	K	L	R	G	H	S	I	T	L	M	Y	A	L	Q	N	F	I	D	Q	L	D	N	P	D	D	L	V	C	V	V	E	K	F	A	V	N	H	I	T	R	K	I	S	A	A	E	F	G	K	I	N	G	P	I	K	K	V
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
Conserved Domain info										•			•																												•	•										•			•
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.
Sequence		L	A	S	K	N	F	G	D	K	Y	A	N	A	W	A	K	L	V	A	V	V	Q	A	A	L
Secondary structure
SS confidence
Disorder																								?	?	?
Disorder confidence
Conserved Domain info																							•

Confidence Key High(9)                     Low (0)

? Disordered ( 14%) Alpha helix ( 79%) Beta strand ( 0%)

CDD sites • heme-binding site

Rank Aligned region

PDB 3sdh chain A Region: 1 - 145 Aligned: 145 Modelled: 145 Confidence: 100.0% Identity: 100% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 1sct chain A Region: 5 - 145 Aligned: 141 Modelled: 141 Confidence: 100.0% Identity: 53% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 3pt8 chain B Region: 6 - 145 Aligned: 140 Modelled: 140 Confidence: 100.0% Identity: 24% PDB header:oxygen transport Chain: B: PDB Molecule:hemoglobin iii; PDBTitle: structure of hbii-iii-cn from lucina pectinata at ph 5.0 Phyre2 PDB 1sct chain B Region: 6 - 145 Aligned: 140 Modelled: 140 Confidence: 100.0% Identity: 56% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 2olp chain B Region: 7 - 145 Aligned: 139 Modelled: 139 Confidence: 100.0% Identity: 25% PDB header:oxygen storage/transport Chain: B: PDB Molecule:hemoglobin ii; PDBTitle: structure and ligand selection of hemoglobin ii from lucina pectinata Phyre2 PDB 1mba chain A Region: 9 - 145 Aligned: 137 Modelled: 137 Confidence: 100.0% Identity: 24% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 4b4y chain A Region: 6 - 145 Aligned: 140 Modelled: 140 Confidence: 100.0% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:neuroglobin; PDBTitle: crystal structure of the neuroglobin from the photosymbiotic2 marine acoel symsagittifera roscoffensis Phyre2 PDB 1hlb chain A Region: 2 - 145 Aligned: 143 Modelled: 144 Confidence: 100.0% Identity: 24% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 1o1n chain A Region: 7 - 145 Aligned: 134 Modelled: 139 Confidence: 100.0% Identity: 17% PDB header:oxygen storage/transport Chain: A: PDB Molecule:hemoglobin alpha chain; PDBTitle: deoxy hemoglobin (a-glyglygly-c:v1m,l29w; b,d:v1m) Phyre2 PDB 1b0b chain A Region: 9 - 145 Aligned: 134 Modelled: 137 Confidence: 100.0% Identity: 19% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 1x3k chain A Region: 5 - 145 Aligned: 138 Modelled: 141 Confidence: 100.0% Identity: 17% PDB header:oxygen storage/transport Chain: A: PDB Molecule:hemoglobin component v; PDBTitle: crystal structure of a hemoglobin component (ta-v) from2 tokunagayusurika akamusi Phyre2 PDB 2lhb chain A Region: 5 - 145 Aligned: 135 Modelled: 141 Confidence: 100.0% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 1ut0 chain A Region: 8 - 145 Aligned: 138 Modelled: 138 Confidence: 100.0% Identity: 23% PDB header:oxygen transport Chain: A: PDB Molecule:cytoglobin; PDBTitle: crystal structure of cytoglobin: the fourth globin type2 discovered in man displays heme hexa-coordination Phyre2 PDB 1urv chain A Region: 8 - 145 Aligned: 138 Modelled: 138 Confidence: 100.0% Identity: 23% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 1ith chain A Region: 8 - 145 Aligned: 136 Modelled: 138 Confidence: 100.0% Identity: 17% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 1h97 chain A Region: 9 - 145 Aligned: 137 Modelled: 137 Confidence: 100.0% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 2zs0 chain A Region: 9 - 145 Aligned: 134 Modelled: 137 Confidence: 100.0% Identity: 16% PDB header:oxygen storage, oxygen transport Chain: A: PDB Molecule:extracellular giant hemoglobin major globin subunit a1; PDBTitle: structural basis for the heterotropic and homotropic interactions of2 invertebrate giant hemoglobin Phyre2 PDB 1x9f chain D Region: 8 - 145 Aligned: 136 Modelled: 138 Confidence: 100.0% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 PDB 1yhu chain W Region: 6 - 145 Aligned: 137 Modelled: 140 Confidence: 100.0% Identity: 21% PDB header:oxygen storage/transport Chain: W: PDB Molecule:hemoglobin b1a chain; PDBTitle: crystal structure of riftia pachyptila c1 hemoglobin reveals novel2 assembly of 24 subunits. Phyre2 PDB 1hbg chain A Region: 8 - 145 Aligned: 133 Modelled: 133 Confidence: 100.0% Identity: 18% Fold: Globin-like Superfamily: Globin-like Family: Globins Phyre2 1 d3sdha_ 2 d1scta_ 3 c3pt8B_ 4 d1sctb_ 5 c2olpB_ 6 d1mbaa_ 7 c4b4yA_ 8 d1hlba_ 9 c1o1nA_ 10 d1b0ba_ 11 c1x3kA_ 12 d2lhba_ 13 c1ut0A_ 14 d1urva_ 15 d1itha_ 16 d1h97a_ 17 c2zs0A_ 18 d1x9fd_ 19 c1yhuW_ 20 d1hbga_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158