Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76049
DateThu Jan 5 12:17:51 GMT 2012
Unique Job IDfefbfce091fd45e9

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2hdwB_
Top template information
PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa
Confidence and coverage
Confidence:100.0% Coverage: 98%
300 residues ( 98% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVLSHPGGGVKEQTAGTYAKKLAE
Secondary structure 
























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Disorder  ????























































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   .........70.........80.........90.........100.........110.........120
Sequence  KGFVTIAYDASYQGESGGEPRQLENPYIRTEDISAVIDYLTTLSYVDNTRIGAMGICAGA
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   .........130.........140.........150.........160.........170.........180
Sequence  GYTANAAIQDRRIKAIGTVSAVNIGSIFRNGWENNVKSIDALPYVEAGSNARTSDISSGE
Secondary structure 














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Disorder 































??????



















?
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   .........190.........200.........210.........220.........230.........240
Sequence  YAIMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPGYATLRSLNQIITYDAYHMAEVY
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Disorder 
??



????
?

?











































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   .........250.........260.........270.........280.........290.........300
Sequence  LTQPTQIVAGSQAGSKWMSDDLYDRASSQDKRYHIVEGANHMDLYDGKAYVAEAISVLAP
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   ......
Sequence  FFEETL
Secondary structure 
SS confidence 





Disorder 


???
Disorder confidence 





 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2hdw chain B

3D model

Region: 1 - 306
Aligned: 300
Modelled: 306
Confidence: 100.0%
Identity: 32%
PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa

Phyre2

PDB 3azq chain A

3D model

Region: 4 - 306
Aligned: 245
Modelled: 247
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg

Phyre2

PDB 3jw8 chain A

3D model

Region: 3 - 306
Aligned: 275
Modelled: 284
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:mgll protein;
PDBTitle: crystal structure of human mono-glyceride lipase

Phyre2

PDB 3hju chain B

3D model

Region: 3 - 306
Aligned: 275
Modelled: 284
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:monoglyceride lipase;
PDBTitle: crystal structure of human monoglyceride lipase

Phyre2

PDB 1l7a chain A

3D model

Region: 1 - 306
Aligned: 245
Modelled: 251
Confidence: 100.0%
Identity: 17%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Acetyl xylan esterase-like

Phyre2

PDB 1k8q chain A

3D model

Region: 4 - 305
Aligned: 300
Modelled: 301
Confidence: 100.0%
Identity: 11%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Gastric lipase

Phyre2

PDB 2ecf chain A

3D model

Region: 1 - 306
Aligned: 240
Modelled: 244
Confidence: 100.0%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase iv;
PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia

Phyre2

PDB 2g5t chain A

3D model

Region: 1 - 306
Aligned: 242
Modelled: 246
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag

Phyre2

PDB 2qtb chain B

3D model

Region: 1 - 306
Aligned: 242
Modelled: 246
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor

Phyre2

PDB 1hlg chain A

3D model

Region: 4 - 305
Aligned: 297
Modelled: 302
Confidence: 100.0%
Identity: 11%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Gastric lipase

Phyre2

PDB 3mve chain B

3D model

Region: 4 - 306
Aligned: 244
Modelled: 260
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase

Phyre2

PDB 2eep chain A

3D model

Region: 4 - 306
Aligned: 237
Modelled: 241
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor

Phyre2

PDB 2hu7 chain A

3D model

Region: 2 - 306
Aligned: 239
Modelled: 247
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase

Phyre2

PDB 1z68 chain A

3D model

Region: 1 - 306
Aligned: 241
Modelled: 244
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit;
PDBTitle: crystal structure of human fibroblast activation protein alpha

Phyre2

PDB 1cr6 chain A

3D model

Region: 8 - 305
Aligned: 278
Modelled: 295
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor

Phyre2

PDB 3k2i chain A

3D model

Region: 2 - 306
Aligned: 250
Modelled: 263
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4;
PDBTitle: human acyl-coenzyme a thioesterase 4

Phyre2

PDB 2y6v chain B

3D model

Region: 12 - 305
Aligned: 285
Modelled: 294
Confidence: 100.0%
Identity: 11%
PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal membrane protein lpx1;
PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i)

Phyre2

PDB 3hlk chain B

3D model

Region: 18 - 306
Aligned: 236
Modelled: 247
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial;
PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2)

Phyre2

PDB 2o2g chain A

3D model

Region: 3 - 306
Aligned: 207
Modelled: 212
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:dienelactone hydrolase;
PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution

Phyre2

PDB 3fcy chain B

3D model

Region: 4 - 306
Aligned: 243
Modelled: 253
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:xylan esterase 1;
PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485

Phyre2
1

c2hdwB_
2

c3azqA_
3

c3jw8A_
4

c3hjuB_
5

d1l7aa_
6

d1k8qa_
7

c2ecfA_
8

c2g5tA_
9

c2qtbB_
10

d1hlga_
11

c3mveB_
12

c2eepA_
13

c2hu7A_
14

c1z68A_
15

c1cr6A_
16

c3k2iA_
17

c2y6vB_
18

c3hlkB_
19

c2o2gA_
20

c3fcyB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2hdwB_



100.0 32 PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa
2c3azqA_



100.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg
3c3jw8A_



100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:mgll protein;
PDBTitle: crystal structure of human mono-glyceride lipase
4c3hjuB_



100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:monoglyceride lipase;
PDBTitle: crystal structure of human monoglyceride lipase
5d1l7aa_



100.0 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
6d1k8qa_



100.0 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
7c2ecfA_



100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase iv;
PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia
8c2g5tA_



100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
9c2qtbB_



100.0 16 PDB header:hydrolase
Chain: B: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
10d1hlga_



100.0 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
11c3mveB_



100.0 16 PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
12c2eepA_



100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor
13c2hu7A_



100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase
14c1z68A_



100.0 16 PDB header:lyase
Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit;
PDBTitle: crystal structure of human fibroblast activation protein alpha
15c1cr6A_



100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor
16c3k2iA_



100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4;
PDBTitle: human acyl-coenzyme a thioesterase 4
17c2y6vB_



100.0 11 PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal membrane protein lpx1;
PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i)
18c3hlkB_



100.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial;
PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2)
19c2o2gA_



100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:dienelactone hydrolase;
PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution
20c3fcyB_



100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:xylan esterase 1;
PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485
21c1l7qA_



not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:cocaine esterase;
PDBTitle: ser117ala mutant of bacterial cocaine esterase coce
22c2wtmC_



not modelled 100.0 17 PDB header:hydrolase
Chain: C: PDB Molecule:est1e;
PDBTitle: est1e from butyrivibrio proteoclasticus
23d1ju3a2



not modelled 100.0 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
24c3i1iA_



not modelled 100.0 12 PDB header:transferase
Chain: A: PDB Molecule:homoserine o-acetyltransferase;
PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis
25d1vlqa_



not modelled 100.0 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
26d2b61a1



not modelled 100.0 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
27c2vavL_



not modelled 100.0 14 PDB header:transferase
Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c
PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak)
28c3llcA_



not modelled 100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:putative hydrolase;
PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution
29c2jbwB_



not modelled 100.0 19 PDB header:hydrolase
Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase;
PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase.
30d1qfma2



not modelled 100.0 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Prolyl oligopeptidase, C-terminal domain
31c3h04A_



not modelled 100.0 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50
32d2vata1



not modelled 100.0 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
33c3ksrA_



not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative serine hydrolase;
PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution
34d2jbwa1



not modelled 99.9 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:2,6-dihydropseudooxynicotine hydrolase-like
35d1mtza_



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
36c3ib3A_



not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:coce/nond family hydrolase;
PDBTitle: crystal structure of sacol2612 - coce/nond family hydrolase from2 staphylococcus aureus
37d1b6ga_



not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
38c3qm1A_



not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:cinnamoyl esterase;
PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii
39c2b9vB_



not modelled 99.9 16 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-amino acid ester hydrolase;
PDBTitle: acetobacter turbidans alpha-amino acid ester hydrolase
40c1xfdD_



not modelled 99.9 13 PDB header:membrane protein
Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6;
PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family
41c3fnbB_



not modelled 99.9 15 PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159
42d1e89a_



not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
43c2e3jA_



not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase ephb;
PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom
44d1xkla_



not modelled 99.9 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
45d3c70a1



not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
46c2cjpA_



not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1)
47c3dqzB_



not modelled 99.9 11 PDB header:lyase
Chain: B: PDB Molecule:alpha-hydroxynitrile lyase-like protein;
PDBTitle: structure of the hydroxynitrile lyase from arabidopsis2 thaliana
48c3nwoA_



not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:proline iminopeptidase;
PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis
49d2b9va2



not modelled 99.9 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
50d1q0ra_



not modelled 99.9 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Aclacinomycin methylesterase RdmC
51d1zd3a2



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
52d1orva2



not modelled 99.9 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
53c3u1tA_



not modelled 99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:dmma haloalkane dehalogenase;
PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin
54d1hkha_



not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
55c3bwxA_



not modelled 99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase;
PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution
56d1mpxa2



not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
57d2bgra2



not modelled 99.9 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
58c1qfmA_



not modelled 99.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:protein (prolyl oligopeptidase);
PDBTitle: prolyl oligopeptidase from porcine muscle
59c3h2iA_



not modelled 99.9 9 PDB header:hydrolase
Chain: A: PDB Molecule:esterase;
PDBTitle: crystal structure of n228w mutant of the rice cell wall2 degrading esterase lipa from xanthomonas oryzae
60c3fobA_



not modelled 99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:bromoperoxidase;
PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis
61c2qmqA_



not modelled 99.9 14 PDB header:signaling protein
Chain: A: PDB Molecule:protein ndrg2;
PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution
62d1cr6a2



not modelled 99.9 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
63d1brta_



not modelled 99.9 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
64c1u2eA_



not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid
PDBTitle: crystal structure of the c-c bond hydrolase mhpc
65c3qvmA_



not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:olei00960;
PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica
66d1c4xa_



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
67c2yysA_



not modelled 99.9 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:proline iminopeptidase-related protein;
PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8
68c2r11D_



not modelled 99.9 15 PDB header:hydrolase
Chain: D: PDB Molecule:carboxylesterase np;
PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution
69d2pl5a1



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
70d1a8qa_



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
71c2xt0A_



not modelled 99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:haloalkane dehalogenase;
PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i
72c3v48B_



not modelled 99.9 11 PDB header:hydrolase
Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd;
PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli
73d1va4a_



not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
74d2rhwa1



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
75c3gzjB_



not modelled 99.9 12 PDB header:hydrolase
Chain: B: PDB Molecule:polyneuridine-aldehyde esterase;
PDBTitle: crystal structure of polyneuridine aldehyde esterase2 complexed with 16-epi-vellosimine
76d1a8sa_



not modelled 99.9 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
77c2bklB_



not modelled 99.9 12 PDB header:hydrolase
Chain: B: PDB Molecule:prolyl endopeptidase;
PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity
78c3kdaB_



not modelled 99.9 15 PDB header:hydrolase
Chain: B: PDB Molecule:cftr inhibitory factor (cif);
PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation
79d1wm1a_



not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
80c1zoiC_



not modelled 99.9 10 PDB header:hydrolase
Chain: C: PDB Molecule:esterase;
PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996
81d2fuka1



not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
82d1dina_



not modelled 99.9 19 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Dienelactone hydrolase
83c2qruA_



not modelled 99.9 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis
84c3qitB_



not modelled 99.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:polyketide synthase;
PDBTitle: thioesterase domain from curacin biosynthetic pathway
85d1azwa_



not modelled 99.9 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
86d1xfda2



not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:DPP6 catalytic domain-like
87c1mpxB_



not modelled 99.9 14 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-amino acid ester hydrolase;
PDBTitle: alpha-amino acid ester hydrolase labeled with selenomethionine
88d1a88a_



not modelled 99.9 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
89c2xe4A_



not modelled 99.9 10 PDB header:hydrolase/inhibitor
Chain: A: PDB Molecule:oligopeptidase b;
PDBTitle: structure of oligopeptidase b from leishmania major
90c3oosA_



not modelled 99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase family protein;
PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne
91c2rauA_



not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative esterase;
PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus2 solfataricus at 1.85 a resolution
92c1wprA_



not modelled 99.9 11 PDB header:signaling protein
Chain: A: PDB Molecule:sigma factor sigb regulation protein rsbq;
PDBTitle: crystal structure of rsbq inhibited by pmsf
93c3f67A_



not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative dienelactone hydrolase;
PDBTitle: crystal structure of putative dienelactone hydrolase from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578
94d1uk8a_



not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
95c2xmzA_



not modelled 99.9 13 PDB header:lyase
Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family;
PDBTitle: structure of menh from s. aureus
96c3e3aA_



not modelled 99.9 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:possible peroxidase bpoc;
PDBTitle: the structure of rv0554 from mycobacterium tuberculosis
97d2hu7a2



not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acylamino-acid-releasing enzyme, C-terminal donain
98c2xuaH_



not modelled 99.9 14 PDB header:hydrolase
Chain: H: PDB Molecule:3-oxoadipate enol-lactonase;
PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400
99d1ehya_



not modelled 99.9 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
100c3a2nF_



not modelled 99.9 10 PDB header:hydrolase
Chain: F: PDB Molecule:haloalkane dehalogenase;
PDBTitle: crystal structure of dbja (wild type type ii p21)
101c2vf2A_



not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis
102d1m33a_



not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Biotin biosynthesis protein BioH
103c2q0xA_



not modelled 99.9 8 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: alpha/beta hydrolase fold protein of unknown function
104d1jfra_



not modelled 99.9 23 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Lipase
105c3om8A_



not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:probable hydrolase;
PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01
106c3dyvA_



not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:esterase d;
PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism
107c3fsgC_



not modelled 99.9 13 PDB header:hydrolase
Chain: C: PDB Molecule:alpha/beta superfamily hydrolase;
PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1
108c3trdA_



not modelled 99.9 22 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase;
PDBTitle: structure of an alpha-beta serine hydrolase homologue from coxiella2 burnetii
109d1mj5a_



not modelled 99.9 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
110c3c5wP_



not modelled 99.9 14 PDB header:hydrolase
Chain: P: PDB Molecule:pp2a-specific methylesterase pme-1;
PDBTitle: complex between pp2a-specific methylesterase pme-1 and pp2a core2 enzyme
111c3iumA_



not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:prolyl endopeptidase;
PDBTitle: appep_wtx opened state
112c3bf7B_



not modelled 99.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:esterase ybff;
PDBTitle: 1.1 resolution structure of ybff, a new esterase from2 escherichia coli: a unique substrate-binding crevice3 generated by domain arrangement
113d1bn7a_



not modelled 99.9 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
114c3bxpA_



not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:putative lipase/esterase;
PDBTitle: crystal structure of a putative carboxylesterase (lp_2923) from2 lactobacillus plantarum wcfs1 at 1.70 a resolution
115c2wj4B_



not modelled 99.9 10 PDB header:oxidoreductase
Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase;
PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine
116d1qo7a_



not modelled 99.9 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
117d2i3da1



not modelled 99.9 20 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
118c2i3dA_



not modelled 99.9 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein atu1826;
PDBTitle: crystal structure of protein of unknown function atu1826, a putative2 alpha/beta hydrolase from agrobacterium tumefaciens
119c2qvbA_



not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:haloalkane dehalogenase 3;
PDBTitle: crystal structure of haloalkane dehalogenase rv2579 from mycobacterium2 tuberculosis
120c1y37A_



not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:fluoroacetate dehalogenase;
PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0