Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP77585
DateThu Jan 5 12:30:48 GMT 2012
Unique Job IDfa52fea45906de62

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1yloA_
Top template information
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein sf2450;
PDBTitle: crystal structure of protein of unknown function (possible2 aminopeptidase) s2589 from shigella flexneri 2a str. 2457t
Confidence and coverage
Confidence:100.0% Coverage:100%
344 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGSVLIRLNESTGPKVMIC
Secondary structure 






















SS confidence 



























































Disorder  ??

























































Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  AHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTREECKIPGLLDGDRQGNDV
Secondary structure 





























SS confidence 



























































Disorder 





















































??



Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  SAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRVMGKAFDDRLGCYLLVTLLRE
Secondary structure 

























SS confidence 



























































Disorder 



























































Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  LHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAIVLDTACWAKNFDYGAANHRQIG
Secondary structure 






































SS confidence 



























































Disorder 






















?


?































Disorder confidence 



























































 
   .........250.........260.........270.........280.........290.........300
Sequence  NGPMLVLSDKSLIAPPKLTAWVETVAAEIGVPLQADMFSNGGTDGGAVHLTGTGVPTVVM
Secondary structure 


























SS confidence 



























































Disorder 








??



























?



















Disorder confidence 



























































 
   .........310.........320.........330.........340.....
Sequence  GPATRHGHCAASIADCRDILQMQQLLSALIQRLTRETVVQLTDFR
Secondary structure 









SS confidence 












































Disorder 









































???
Disorder confidence 












































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1ylo chain A

3D model

Region: 2 - 345
Aligned: 344
Modelled: 338
Confidence: 100.0%
Identity: 95%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein sf2450;
PDBTitle: crystal structure of protein of unknown function (possible2 aminopeptidase) s2589 from shigella flexneri 2a str. 2457t

Phyre2

PDB 1y0y chain A

3D model

Region: 1 - 338
Aligned: 332
Modelled: 334
Confidence: 100.0%
Identity: 31%
PDB header:hydrolase
Chain: A: PDB Molecule:frv operon protein frvx;
PDBTitle: crystal structure of tetrahedral aminopeptidase from p. horikoshii in2 complex with amastatin

Phyre2

PDB 1vhe chain A

3D model

Region: 1 - 342
Aligned: 342
Modelled: 342
Confidence: 100.0%
Identity: 33%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:aminopeptidase/glucanase homolog;
PDBTitle: crystal structure of a aminopeptidase/glucanase homolog

Phyre2

PDB 3kl9 chain F

3D model

Region: 3 - 344
Aligned: 332
Modelled: 342
Confidence: 100.0%
Identity: 31%
PDB header:hydrolase
Chain: F: PDB Molecule:glutamyl aminopeptidase;
PDBTitle: crystal structure of pepa from streptococcus pneumoniae

Phyre2

PDB 3isx chain A

3D model

Region: 3 - 330
Aligned: 323
Modelled: 322
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: crystal structure of endoglucanase (tm1050) from thermotoga2 maritima at 1.40 a resolution

Phyre2

PDB 2pe3 chain A

3D model

Region: 2 - 335
Aligned: 323
Modelled: 329
Confidence: 100.0%
Identity: 30%
PDB header:hydrolase
Chain: A: PDB Molecule:354aa long hypothetical operon protein frv;
PDBTitle: crystal structure of frv operon protein frvx (ph1821)from pyrococcus2 horikoshii ot3

Phyre2

PDB 2cf4 chain A

3D model

Region: 3 - 333
Aligned: 321
Modelled: 331
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:protein ph0519;
PDBTitle: pyrococcus horikoshii tet1 peptidase can assemble into a2 tetrahedron or a large octahedral shell

Phyre2

PDB 3rza chain A

3D model

Region: 3 - 336
Aligned: 325
Modelled: 327
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:tripeptidase;
PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution

Phyre2

PDB 1vho chain A

3D model

Region: 3 - 334
Aligned: 307
Modelled: 312
Confidence: 100.0%
Identity: 25%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: crystal structure of a putative peptidase/endoglucanase

Phyre2

PDB 3tx8 chain A

3D model

Region: 3 - 332
Aligned: 327
Modelled: 330
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase;
PDBTitle: crystal structure of a succinyl-diaminopimelate desuccinylase (arge)2 from corynebacterium glutamicum atcc 13032 at 2.97 a resolution

Phyre2

PDB 1vgy chain B

3D model

Region: 3 - 333
Aligned: 328
Modelled: 331
Confidence: 100.0%
Identity: 16%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:succinyl-diaminopimelate desuccinylase;
PDBTitle: crystal structure of succinyl diaminopimelate desuccinylase

Phyre2

PDB 3gb0 chain A

3D model

Region: 3 - 335
Aligned: 324
Modelled: 331
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:peptidase t;
PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution

Phyre2

PDB 1ylo chain A domain 2

3D model

Region: 1 - 345
Aligned: 264
Modelled: 262
Confidence: 100.0%
Identity: 94%
Fold: Phosphorylase/hydrolase-like
Superfamily: Zn-dependent exopeptidases
Family: Bacterial dinuclear zinc exopeptidases

Phyre2

PDB 3pfo chain B

3D model

Region: 3 - 334
Aligned: 331
Modelled: 319
Confidence: 100.0%
Identity: 12%
PDB header:hydrolase
Chain: B: PDB Molecule:putative acetylornithine deacetylase;
PDBTitle: crystal structure of a putative acetylornithine deacetylase (rpa2325)2 from rhodopseudomonas palustris cga009 at 1.90 a resolution

Phyre2

PDB 2qyv chain B

3D model

Region: 3 - 335
Aligned: 333
Modelled: 325
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:xaa-his dipeptidase;
PDBTitle: crystal structure of putative xaa-his dipeptidase (yp_718209.1) from2 haemophilus somnus 129pt at 2.11 a resolution

Phyre2

PDB 3mru chain B

3D model

Region: 3 - 337
Aligned: 335
Modelled: 333
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:aminoacyl-histidine dipeptidase;
PDBTitle: crystal structure of aminoacylhistidine dipeptidase from vibrio2 alginolyticus

Phyre2

PDB 2gre chain C

3D model

Region: 3 - 331
Aligned: 294
Modelled: 308
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: C: PDB Molecule:deblocking aminopeptidase;
PDBTitle: crystal structure of deblocking aminopeptidase from bacillus cereus

Phyre2

PDB 1cg2 chain D

3D model

Region: 3 - 335
Aligned: 326
Modelled: 333
Confidence: 100.0%
Identity: 14%
PDB header:metallocarboxypeptidase
Chain: D: PDB Molecule:carboxypeptidase g2;
PDBTitle: carboxypeptidase g2

Phyre2

PDB 2fvg chain A

3D model

Region: 4 - 338
Aligned: 307
Modelled: 323
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: crystal structure of endoglucanase (tm1049) from thermotoga maritima2 at 2.01 a resolution

Phyre2

PDB 2rb7 chain A

3D model

Region: 3 - 335
Aligned: 324
Modelled: 333
Confidence: 100.0%
Identity: 11%
PDB header:hydrolase
Chain: A: PDB Molecule:peptidase, m20/m25/m40 family;
PDBTitle: crystal structure of co-catalytic metallopeptidase (yp_387682.1) from2 desulfovibrio desulfuricans g20 at 1.60 a resolution

Phyre2
1

c1yloA_
2

c1y0yA_
3

c1vheA_
4

c3kl9F_
5

c3isxA_
6

c2pe3A_
7

c2cf4A_
8

c3rzaA_
9

c1vhoA_
10

c3tx8A_
11

c1vgyB_
12

c3gb0A_
13

d1yloa2
14

c3pfoB_
15

c2qyvB_
16

c3mruB_
17

c2greC_
18

c1cg2D_
19

c2fvgA_
20

c2rb7A_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68



69



70



71



72



73



74



75



76



77



78



79



80



81



82



83



84



85



86



87



88



89



90



91



92



93



94



95



96



97



98



99



100



101



102



103



104



105



106



107



108



109



110



111



112



113



114



115



116



117



118



119



120



121



122






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1yloA_



100.0 95 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein sf2450;
PDBTitle: crystal structure of protein of unknown function (possible2 aminopeptidase) s2589 from shigella flexneri 2a str. 2457t
2c1y0yA_



100.0 31 PDB header:hydrolase
Chain: A: PDB Molecule:frv operon protein frvx;
PDBTitle: crystal structure of tetrahedral aminopeptidase from p. horikoshii in2 complex with amastatin
3c1vheA_



100.0 33 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:aminopeptidase/glucanase homolog;
PDBTitle: crystal structure of a aminopeptidase/glucanase homolog
4c3kl9F_



100.0 31 PDB header:hydrolase
Chain: F: PDB Molecule:glutamyl aminopeptidase;
PDBTitle: crystal structure of pepa from streptococcus pneumoniae
5c3isxA_



100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: crystal structure of endoglucanase (tm1050) from thermotoga2 maritima at 1.40 a resolution
6c2pe3A_



100.0 30 PDB header:hydrolase
Chain: A: PDB Molecule:354aa long hypothetical operon protein frv;
PDBTitle: crystal structure of frv operon protein frvx (ph1821)from pyrococcus2 horikoshii ot3
7c2cf4A_



100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:protein ph0519;
PDBTitle: pyrococcus horikoshii tet1 peptidase can assemble into a2 tetrahedron or a large octahedral shell
8c3rzaA_



100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:tripeptidase;
PDBTitle: crystal structure of a tripeptidase (sav1512) from staphylococcus2 aureus subsp. aureus mu50 at 2.10 a resolution
9c1vhoA_



100.0 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: crystal structure of a putative peptidase/endoglucanase
10c3tx8A_



100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase;
PDBTitle: crystal structure of a succinyl-diaminopimelate desuccinylase (arge)2 from corynebacterium glutamicum atcc 13032 at 2.97 a resolution
11c1vgyB_



100.0 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:succinyl-diaminopimelate desuccinylase;
PDBTitle: crystal structure of succinyl diaminopimelate desuccinylase
12c3gb0A_



100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:peptidase t;
PDBTitle: crystal structure of aminopeptidase pept (np_980509.1) from bacillus2 cereus atcc 10987 at 2.04 a resolution
13d1yloa2



100.0 94 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
14c3pfoB_



100.0 12 PDB header:hydrolase
Chain: B: PDB Molecule:putative acetylornithine deacetylase;
PDBTitle: crystal structure of a putative acetylornithine deacetylase (rpa2325)2 from rhodopseudomonas palustris cga009 at 1.90 a resolution
15c2qyvB_



100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:xaa-his dipeptidase;
PDBTitle: crystal structure of putative xaa-his dipeptidase (yp_718209.1) from2 haemophilus somnus 129pt at 2.11 a resolution
16c3mruB_



100.0 16 PDB header:hydrolase
Chain: B: PDB Molecule:aminoacyl-histidine dipeptidase;
PDBTitle: crystal structure of aminoacylhistidine dipeptidase from vibrio2 alginolyticus
17c2greC_



100.0 19 PDB header:hydrolase
Chain: C: PDB Molecule:deblocking aminopeptidase;
PDBTitle: crystal structure of deblocking aminopeptidase from bacillus cereus
18c1cg2D_



100.0 14 PDB header:metallocarboxypeptidase
Chain: D: PDB Molecule:carboxypeptidase g2;
PDBTitle: carboxypeptidase g2
19c2fvgA_



100.0 22 PDB header:hydrolase
Chain: A: PDB Molecule:endoglucanase;
PDBTitle: crystal structure of endoglucanase (tm1049) from thermotoga maritima2 at 2.01 a resolution
20c2rb7A_



100.0 11 PDB header:hydrolase
Chain: A: PDB Molecule:peptidase, m20/m25/m40 family;
PDBTitle: crystal structure of co-catalytic metallopeptidase (yp_387682.1) from2 desulfovibrio desulfuricans g20 at 1.60 a resolution
21c2pokB_



not modelled 100.0 14 PDB header:hydrolase
Chain: B: PDB Molecule:peptidase, m20/m25/m40 family;
PDBTitle: crystal structure of a m20 family metallo peptidase from streptococcus2 pneumoniae
22c3dljB_



not modelled 100.0 13 PDB header:hydrolase
Chain: B: PDB Molecule:beta-ala-his dipeptidase;
PDBTitle: crystal structure of human carnosine dipeptidase 1
23c3ifeA_



not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:peptidase t;
PDBTitle: 1.55 angstrom resolution crystal structure of peptidase t (pept-1)2 from bacillus anthracis str. 'ames ancestor'.
24c3ct9B_



not modelled 100.0 13 PDB header:hydrolase
Chain: B: PDB Molecule:acetylornithine deacetylase;
PDBTitle: crystal structure of a putative zinc peptidase (np_812461.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.31 a resolution
25c3ic1A_



not modelled 100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase;
PDBTitle: crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase2 from haemophilus influenzae
26c1vixA_



not modelled 100.0 11 PDB header:hydrolase
Chain: A: PDB Molecule:peptidase t;
PDBTitle: crystal structure of a putative peptidase t
27c1ysjB_



not modelled 100.0 12 PDB header:hydrolase
Chain: B: PDB Molecule:protein yxep;
PDBTitle: crystal structure of bacillus subtilis yxep protein (apc1829), a2 dinuclear metal binding peptidase from m20 family
28c2q43A_



not modelled 100.0 10 PDB header:hydrolase
Chain: A: PDB Molecule:iaa-amino acid hydrolase ilr1-like 2;
PDBTitle: ensemble refinement of the protein crystal structure of iaa-aminoacid2 hydrolase from arabidopsis thaliana gene at5g56660
29c2zogA_



not modelled 100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:cytosolic non-specific dipeptidase;
PDBTitle: crystal structure of mouse carnosinase cn2 complexed with zn and2 bestatin
30d1xfoa2



not modelled 100.0 32 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
31c3pfeA_



not modelled 100.0 9 PDB header:hydrolase
Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase;
PDBTitle: crystal structure of a m20a metallo peptidase (dape, lpg0809) from2 legionella pneumophila subsp. pneumophila str. philadelphia 1 at 1.503 a resolution
32c3cpxC_



not modelled 100.0 20 PDB header:hydrolase
Chain: C: PDB Molecule:aminopeptidase, m42 family;
PDBTitle: crystal structure of putative m42 glutamyl aminopeptidase2 (yp_676701.1) from cytophaga hutchinsonii atcc 33406 at 2.39 a3 resolution
33c2v8gD_



not modelled 100.0 14 PDB header:hydrolase
Chain: D: PDB Molecule:beta-alanine synthase;
PDBTitle: crystal structure of beta-alanine synthase from2 saccharomyces kluyveri in complex with the product beta-3 alanine
34c2f7vA_



not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:aectylcitrulline deacetylase;
PDBTitle: structure of acetylcitrulline deacetylase complexed with2 one co
35c3ramC_



not modelled 100.0 15 PDB header:hydrolase
Chain: C: PDB Molecule:hmra protein;
PDBTitle: crystal structure of hmra
36c2imoA_



not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:allantoate amidohydrolase;
PDBTitle: crystal structure of allantoate amidohydrolase from escherichia coli2 at ph 4.6
37c3n5fB_



not modelled 100.0 14 PDB header:hydrolase
Chain: B: PDB Molecule:n-carbamoyl-l-amino acid hydrolase;
PDBTitle: crystal structure of l-n-carbamoylase from geobacillus2 stearothermophilus cect43
38d1vhea2



not modelled 100.0 35 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
39c1lfwA_



not modelled 100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:pepv;
PDBTitle: crystal structure of pepv
40d1vixa1



not modelled 100.0 16 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
41d1vhoa2



not modelled 100.0 29 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
42d1fnoa4



not modelled 100.0 16 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
43c3khzA_



not modelled 100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative dipeptidase sacol1801;
PDBTitle: crystal structure of r350a mutant of staphylococcus aureus2 metallopeptidase (sapep/dape) in the apo-form
44d1z2la1



not modelled 100.0 15 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
45d2fvga2



not modelled 100.0 24 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
46c3l6sA_



not modelled 100.0 18 PDB header:hydrolase
Chain: A: PDB Molecule:aspartyl aminopeptidase;
PDBTitle: crystal structure of human aspartyl aminopeptidase (dnpep),2 in complex with aspartic acid hydroxamate
47d2grea2



not modelled 99.9 18 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
48c3t6mA_



not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:succinyl-diaminopimelate desuccinylase;
PDBTitle: crystal structure of the catalytic domain of dape protein from2 v.cholerea in the zn bound form
49c2glfB_



not modelled 99.9 19 PDB header:hydrolase
Chain: B: PDB Molecule:probable m18-family aminopeptidase 1;
PDBTitle: crystal structure of aminipeptidase (m18 family) from thermotoga2 maritima
50d1cg2a1



not modelled 99.9 19 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
51d1lfwa1



not modelled 99.9 19 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
52c3io1B_



not modelled 99.9 10 PDB header:hydrolase
Chain: B: PDB Molecule:aminobenzoyl-glutamate utilization protein;
PDBTitle: crystal structure of aminobenzoyl-glutamate utilization2 protein from klebsiella pneumoniae
53c2ijzF_



not modelled 99.9 18 PDB header:hydrolase
Chain: F: PDB Molecule:probable m18-family aminopeptidase 2;
PDBTitle: crystal structure of aminopeptidase
54d1r3na1



not modelled 99.9 21 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
55d1y0ya2



not modelled 99.9 30 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
56c1y7eA_



not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:probable m18-family aminopeptidase 1;
PDBTitle: the crystal structure of aminopeptidase i from borrelia burgdorferi2 b31
57d1xmba1



not modelled 99.9 15 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
58c2gljR_



not modelled 99.8 19 PDB header:hydrolase
Chain: R: PDB Molecule:
PDBTitle: crystal structure of aminopeptidase i from clostridium2 acetobutylicum
59d1vgya1



not modelled 99.8 12 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
60d1ysja1



not modelled 99.8 14 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
61c1q7lA_



not modelled 99.7 13 PDB header:hydrolase
Chain: A: PDB Molecule:aminoacylase-1;
PDBTitle: zn-binding domain of the t347g mutant of human aminoacylase-2 i
62d1y7ea2



not modelled 99.7 21 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
63d1tkja1



not modelled 99.5 19 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
64c3tc8A_



not modelled 99.5 16 PDB header:hydrolase
Chain: A: PDB Molecule:leucine aminopeptidase;
PDBTitle: crystal structure of a hypothetical zn-dependent exopeptidase2 (bdi_3547) from parabacteroides distasonis atcc 8503 at 1.06 a3 resolution
65c3guxA_



not modelled 99.4 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative zn-dependent exopeptidase;
PDBTitle: crystal structure of a putative zn-dependent exopeptidase (bvu_1317)2 from bacteroides vulgatus atcc 8482 at 1.80 a resolution
66d1rtqa_



not modelled 99.4 11 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Bacterial dinuclear zinc exopeptidases
67c3pb6X_



not modelled 99.3 20 PDB header:transferase
Chain: X: PDB Molecule:glutaminyl-peptide cyclotransferase-like protein;
PDBTitle: crystal structure of the catalytic domain of human golgi-resident2 glutaminyl cyclase at ph 6.5
68c1q7lB_



not modelled 99.2 17 PDB header:hydrolase
Chain: B: PDB Molecule:aminoacylase-1;
PDBTitle: zn-binding domain of the t347g mutant of human aminoacylase-2 i
69c2ek8A_



not modelled 99.1 16 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: aminopeptidase from aneurinibacillus sp. strain am-1
70d2afwa1



not modelled 99.0 14 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Glutaminyl-peptide cyclotransferase-like
71c3iibA_



not modelled 98.8 22 PDB header:hydrolase
Chain: A: PDB Molecule:peptidase m28;
PDBTitle: crystal structure of peptidase m28 precursor (yp_926796.1) from2 shewanella amazonensis sb2b at 1.70 a resolution
72d1vgya2



not modelled 98.1 12 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
73d3bi1a3



not modelled 98.1 14 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:FolH catalytic domain-like
74c2ootA_



not modelled 97.9 22 PDB header:hydrolase
Chain: A: PDB Molecule:glutamate carboxypeptidase 2;
PDBTitle: a high resolution structure of ligand-free human glutamate2 carboxypeptidase ii
75c1cx8F_



not modelled 97.8 17 PDB header:metal transport
Chain: F: PDB Molecule:transferrin receptor protein;
PDBTitle: crytal structure of the ectodomain of human transferrin receptor
76c3rbuA_



not modelled 97.7 17 PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:glutamate carboxypeptidase 2;
PDBTitle: n-terminally avitev-tagged human glutamate carboxypeptidase ii in2 complex with 2-pmpa
77d1z2la2



not modelled 97.7 8 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
78c3k9tA_



not modelled 97.6 12 PDB header:hydrolase
Chain: A: PDB Molecule:putative peptidase;
PDBTitle: crystal structure of putative peptidase (np_348812.1) from clostridium2 acetobutylicum at 2.37 a resolution
79d1de4c3



not modelled 97.6 14 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:FolH catalytic domain-like
80d1cg2a2



not modelled 97.6 5 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
81d1r3na2



not modelled 97.5 5 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
82d2grea1



not modelled 96.8 26 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily:Aminopeptidase/glucanase lid domain
Family:Aminopeptidase/glucanase lid domain
83d1yloa1



not modelled 96.2 94 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily:Aminopeptidase/glucanase lid domain
Family:Aminopeptidase/glucanase lid domain
84d1lfwa2



not modelled 95.9 5 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
85d1vhea1



not modelled 94.4 31 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily:Aminopeptidase/glucanase lid domain
Family:Aminopeptidase/glucanase lid domain
86d1ysja2



not modelled 93.9 10 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
87d1y0ya1



not modelled 91.3 29 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily:Aminopeptidase/glucanase lid domain
Family:Aminopeptidase/glucanase lid domain
88c3ij3A_



not modelled 87.6 16 PDB header:hydrolase
Chain: A: PDB Molecule:cytosol aminopeptidase;
PDBTitle: 1.8 angstrom resolution crystal structure of cytosol aminopeptidase2 from coxiella burnetii
89c3jruB_



not modelled 84.2 6 PDB header:hydrolase
Chain: B: PDB Molecule:probable cytosol aminopeptidase;
PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331
90c3h8gC_



not modelled 81.9 13 PDB header:hydrolase
Chain: C: PDB Molecule:cytosol aminopeptidase;
PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida
91c3kzwD_



not modelled 77.1 11 PDB header:hydrolase
Chain: D: PDB Molecule:cytosol aminopeptidase;
PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col
92c2hc9A_



not modelled 76.2 6 PDB header:hydrolase
Chain: A: PDB Molecule:leucine aminopeptidase 1;
PDBTitle: structure of caenorhabditis elegans leucine aminopeptidase-zinc2 complex (lap1)
93c3kr5E_



not modelled 71.7 12 PDB header:hydrolase
Chain: E: PDB Molecule:m17 leucyl aminopeptidase;
PDBTitle: structure of a protease 4
94c1lanA_



not modelled 71.5 14 PDB header:hydrolase (alpha-aminoacylpeptide)
Chain: A: PDB Molecule:leucine aminopeptidase;
PDBTitle: leucine aminopeptidase complex with l-leucinal
95d2fvga1



not modelled 71.4 29 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily:Aminopeptidase/glucanase lid domain
Family:Aminopeptidase/glucanase lid domain
96c3peiA_



not modelled 63.8 12 PDB header:hydrolase
Chain: A: PDB Molecule:cytosol aminopeptidase;
PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis
97c3hlyA_



not modelled 57.6 8 PDB header:flavoprotein
Chain: A: PDB Molecule:flavodoxin-like domain;
PDBTitle: crystal structure of the flavodoxin-like domain from2 synechococcus sp q5mzp6_synp6 protein. northeast structural3 genomics consortium target snr135d.
98d1vmea1



not modelled 56.1 4 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
99c3fniA_



not modelled 54.8 8 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative diflavin flavoprotein a 3;
PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a
100c2p4sA_



not modelled 54.2 15 PDB header:transferase
Chain: A: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: structure of purine nucleoside phosphorylase from anopheles gambiae in2 complex with dadme-immh
101c1gytG_



not modelled 51.6 15 PDB header:hydrolase
Chain: G: PDB Molecule:cytosol aminopeptidase;
PDBTitle: e. coli aminopeptidase a (pepa)
102c2hnbA_



not modelled 51.5 12 PDB header:electron transport
Chain: A: PDB Molecule:protein mioc;
PDBTitle: solution structure of a bacterial holo-flavodoxin
103c3f6sI_



not modelled 50.8 19 PDB header:electron transport
Chain: I: PDB Molecule:flavodoxin;
PDBTitle: desulfovibrio desulfuricans (atcc 29577) oxidized flavodoxin2 alternate conformers
104d2fz5a1



not modelled 48.3 3 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
105d1ycga1



not modelled 47.8 15 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
106d1lama1



not modelled 47.1 15 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Leucine aminopeptidase, C-terminal domain
107d1f4pa_



not modelled 47.0 12 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
108d1e5da1



not modelled 46.6 15 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
109d1gyta2



not modelled 42.7 14 Fold:Phosphorylase/hydrolase-like
Superfamily:Zn-dependent exopeptidases
Family:Leucine aminopeptidase, C-terminal domain
110d1ykga1



not modelled 41.8 12 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Cytochrome p450 reductase N-terminal domain-like
111d5nula_



not modelled 39.3 8 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
112c1bvyF_



not modelled 38.2 8 PDB header:oxidoreductase
Chain: F: PDB Molecule:protein (cytochrome p450 bm-3);
PDBTitle: complex of the heme and fmn-binding domains of the2 cytochrome p450(bm-3)
113d1bvyf_



not modelled 38.2 8 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
114d1ag9a_



not modelled 36.9 4 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
115d1xmba2



not modelled 32.0 10 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
116d1b1ca_



not modelled 30.4 15 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Cytochrome p450 reductase N-terminal domain-like
117c1vmeB_



not modelled 27.9 4 PDB header:electron transport
Chain: B: PDB Molecule:flavoprotein;
PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution
118d1ydga_



not modelled 25.5 19 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:WrbA-like
119d1oboa_



not modelled 24.2 12 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
120c2zkiH_



not modelled 23.7 20 PDB header:transcription
Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding
PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0