Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31828
DateThu Jan 5 11:48:53 GMT 2012
Unique Job IDf5118e3e834c0a41

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2jbuB_
Top template information
PDB header:hydrolase
Chain: B: PDB Molecule:insulin-degrading enzyme;
PDBTitle: crystal structure of human insulin degrading enzyme2 complexed with co-purified peptides.
Confidence and coverage
Confidence:100.0% Coverage: 94%
871 residues ( 94% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMIYPHAHPKDQVNL
Secondary structure 
























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Disorder  ????














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   .........70.........80.........90.........100.........110.........120
Sequence  WLQIHTGSLQEEDNELGVAHFVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYD
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   .........130.........140.........150.........160.........170.........180
Sequence  ETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVITEEWRAHQDAKWRTSQ
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?
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   .........190.........200.........210.........220.........230.........240
Sequence  ARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
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   .........250.........260.........270.........280.........290.........300
Sequence  LIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRVNGIALYYRLPMVQVNDEQSF
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Disorder 








??????????
???
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   .........310.........320.........330.........340.........350.........360
Sequence  IEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQDA
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   .........370.........380.........390.........400.........410.........420
Sequence  ANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQAERDLRMLTSRLASSSLNNTP
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   .........430.........440.........450.........460.........470.........480
Sequence  FLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILAL
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??
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   .........490.........500.........510.........520.........530.........540
Sequence  EKEYANKKLAAYVFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGE
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Disorder 

??
??

?????

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   .........550.........560.........570.........580.........590.........600
Sequence  EQKLQIIAVSNKGDLSFPAQQKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKV
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   .........610.........620.........630.........640.........650.........660
Sequence  SGMNTLLSVSARTNNPEPGFQLINQRITHSTINDNIWASLQNAQIQALKTLDQRPAEKFA
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   .........670.........680.........690.........700.........710.........720
Sequence  QQMYETRYADDRTKLLQENQIAQFTAADALAADRQLFSSPADITFVIVGNVAEDKLVALI
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   .........730.........740.........750.........760.........770.........780
Sequence  TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLPTRMA
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   .........790.........800.........810.........820.........830.........840
Sequence  LDAFNVALAKDLRVNIREQASGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLAN
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   .........850.........860.........870.........880.........890.........900
Sequence  EVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQL
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   .........910.........920.........930.
Sequence  LKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
Secondary structure 











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Disorder 



























???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2jbu chain B

3D model

Region: 30 - 931
Aligned: 871
Modelled: 897
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: B: PDB Molecule:insulin-degrading enzyme;
PDBTitle: crystal structure of human insulin degrading enzyme2 complexed with co-purified peptides.

Phyre2

PDB 2wk3 chain A

3D model

Region: 30 - 929
Aligned: 870
Modelled: 897
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:insulin degrading enzyme;
PDBTitle: crystal structure of human insulin-degrading enzyme in2 complex with amyloid-beta (1-42)

Phyre2

PDB 1q2l chain A

3D model

Region: 32 - 928
Aligned: 863
Modelled: 884
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:protease iii;
PDBTitle: crystal structure of pitrilysin

Phyre2

PDB 2fge chain A

3D model

Region: 35 - 931
Aligned: 870
Modelled: 883
Confidence: 100.0%
Identity: 10%
PDB header:hydrolase, plant protein
Chain: A: PDB Molecule:zinc metalloprotease (insulinase family);
PDBTitle: crystal structure of presequence protease prep from2 arabidopsis thaliana

Phyre2

PDB 3go9 chain A

3D model

Region: 18 - 486
Aligned: 457
Modelled: 456
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:insulinase family protease;
PDBTitle: predicted insulinase family protease from yersinia pestis

Phyre2

PDB 1sqp chain A

3D model

Region: 23 - 468
Aligned: 423
Modelled: 439
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:ubiquinol-cytochrome-c reductase complex core protein i,
PDBTitle: crystal structure analysis of bovine bc1 with myxothiazol

Phyre2

PDB 1hr9 chain D

3D model

Region: 33 - 466
Aligned: 417
Modelled: 431
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase
Chain: D: PDB Molecule:mitochondrial processing peptidase beta subunit;
PDBTitle: yeast mitochondrial processing peptidase beta-e73q mutant2 complexed with malate dehydrogenase signal peptide

Phyre2

PDB 1nu1 chain A

3D model

Region: 23 - 468
Aligned: 423
Modelled: 439
Confidence: 100.0%
Identity: 18%
PDB header:oxidoreductase
Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein i,
PDBTitle: crystal structure of mitochondrial cytochrome bc1 complexed with 2-2 nonyl-4-hydroxyquinoline n-oxide (nqno)

Phyre2

PDB 1hr6 chain C

3D model

Region: 34 - 465
Aligned: 411
Modelled: 430
Confidence: 100.0%
Identity: 13%
PDB header:hydrolase
Chain: C: PDB Molecule:mitochondrial processing peptidase alpha subunit;
PDBTitle: yeast mitochondrial processing peptidase

Phyre2

PDB 3ami chain B

3D model

Region: 31 - 465
Aligned: 417
Modelled: 426
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: B: PDB Molecule:zinc peptidase;
PDBTitle: the crystal structure of the m16b metallopeptidase subunit from2 sphingomonas sp. a1

Phyre2

PDB 3eoq chain B

3D model

Region: 35 - 465
Aligned: 405
Modelled: 424
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: B: PDB Molecule:putative zinc protease;
PDBTitle: the crystal structure of putative zinc protease beta-2 subunit from thermus thermophilus hb8

Phyre2

PDB 3hdi chain A

3D model

Region: 35 - 469
Aligned: 409
Modelled: 428
Confidence: 100.0%
Identity: 22%
PDB header:hydrolase
Chain: A: PDB Molecule:processing protease;
PDBTitle: crystal structure of bacillus halodurans metallo peptidase

Phyre2

PDB 1l0l chain B

3D model

Region: 30 - 472
Aligned: 413
Modelled: 433
Confidence: 100.0%
Identity: 15%
PDB header:oxidoreductase
Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein 2;
PDBTitle: structure of bovine mitochondrial cytochrome bc1 complex with a bound2 fungicide famoxadone

Phyre2

PDB 3gwb chain A

3D model

Region: 34 - 466
Aligned: 407
Modelled: 419
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:peptidase m16 inactive domain family protein;
PDBTitle: crystal structure of peptidase m16 inactive domain from pseudomonas2 fluorescens. northeast structural genomics target plr293l

Phyre2

PDB 3amj chain B

3D model

Region: 34 - 464
Aligned: 412
Modelled: 431
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:zinc peptidase inactive subunit;
PDBTitle: the crystal structure of the heterodimer of m16b peptidase from2 sphingomonas sp. a1

Phyre2

PDB 3cx5 chain L

3D model

Region: 38 - 466
Aligned: 399
Modelled: 415
Confidence: 100.0%
Identity: 16%
PDB header:oxidoreductase
Chain: L: PDB Molecule:cytochrome b-c1 complex subunit 1, mitochondrial;
PDBTitle: structure of complex iii with bound cytochrome c in reduced2 state and definition of a minimal core interface for3 electron transfer.

Phyre2

PDB 3d3y chain A

3D model

Region: 33 - 459
Aligned: 407
Modelled: 424
Confidence: 100.0%
Identity: 16%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a conserved protein from enterococcus faecalis2 v583

Phyre2

PDB 2fge chain A domain 4

3D model

Region: 35 - 255
Aligned: 211
Modelled: 215
Confidence: 100.0%
Identity: 16%
Fold: LuxS/MPP-like metallohydrolase
Superfamily: LuxS/MPP-like metallohydrolase
Family: MPP-like

Phyre2

PDB 1ppj chain A domain 1

3D model

Region: 23 - 263
Aligned: 232
Modelled: 241
Confidence: 100.0%
Identity: 24%
Fold: LuxS/MPP-like metallohydrolase
Superfamily: LuxS/MPP-like metallohydrolase
Family: MPP-like

Phyre2

PDB 3cxh chain M

3D model

Region: 44 - 401
Aligned: 317
Modelled: 344
Confidence: 100.0%
Identity: 15%
PDB header:oxidoreductase
Chain: M: PDB Molecule:cytochrome b-c1 complex subunit 2, mitochondrial;
PDBTitle: structure of yeast complex iii with isoform-2 cytochrome c2 bound and definition of a minimal core interface for3 electron transfer.

Phyre2
1

c2jbuB_
2

c2wk3A_
3

c1q2lA_
4

c2fgeA_
5

c3go9A_
6

c1sqpA_
7

c1hr9D_
8

c1nu1A_
9

c1hr6C_
10

c3amiB_
11

c3eoqB_
12

c3hdiA_
13

c1l0lB_
14

c3gwbA_
15

c3amjB_
16

c3cx5L_
17

c3d3yA_
18

d2fgea4
19

d1ppja1
20

c3cxhM_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2jbuB_



100.0 14 PDB header:hydrolase
Chain: B: PDB Molecule:insulin-degrading enzyme;
PDBTitle: crystal structure of human insulin degrading enzyme2 complexed with co-purified peptides.
2c2wk3A_



100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:insulin degrading enzyme;
PDBTitle: crystal structure of human insulin-degrading enzyme in2 complex with amyloid-beta (1-42)
3c1q2lA_



100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:protease iii;
PDBTitle: crystal structure of pitrilysin
4c2fgeA_



100.0 10 PDB header:hydrolase, plant protein
Chain: A: PDB Molecule:zinc metalloprotease (insulinase family);
PDBTitle: crystal structure of presequence protease prep from2 arabidopsis thaliana
5c3go9A_



100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:insulinase family protease;
PDBTitle: predicted insulinase family protease from yersinia pestis
6c1sqpA_



100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:ubiquinol-cytochrome-c reductase complex core protein i,
PDBTitle: crystal structure analysis of bovine bc1 with myxothiazol
7c1hr9D_



100.0 17 PDB header:hydrolase
Chain: D: PDB Molecule:mitochondrial processing peptidase beta subunit;
PDBTitle: yeast mitochondrial processing peptidase beta-e73q mutant2 complexed with malate dehydrogenase signal peptide
8c1nu1A_



100.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein i,
PDBTitle: crystal structure of mitochondrial cytochrome bc1 complexed with 2-2 nonyl-4-hydroxyquinoline n-oxide (nqno)
9c1hr6C_



100.0 13 PDB header:hydrolase
Chain: C: PDB Molecule:mitochondrial processing peptidase alpha subunit;
PDBTitle: yeast mitochondrial processing peptidase
10c3amiB_



100.0 20 PDB header:hydrolase
Chain: B: PDB Molecule:zinc peptidase;
PDBTitle: the crystal structure of the m16b metallopeptidase subunit from2 sphingomonas sp. a1
11c3eoqB_



100.0 20 PDB header:hydrolase
Chain: B: PDB Molecule:putative zinc protease;
PDBTitle: the crystal structure of putative zinc protease beta-2 subunit from thermus thermophilus hb8
12c3hdiA_



100.0 22 PDB header:hydrolase
Chain: A: PDB Molecule:processing protease;
PDBTitle: crystal structure of bacillus halodurans metallo peptidase
13c1l0lB_



100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:ubiquinol-cytochrome c reductase complex core protein 2;
PDBTitle: structure of bovine mitochondrial cytochrome bc1 complex with a bound2 fungicide famoxadone
14c3gwbA_



100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:peptidase m16 inactive domain family protein;
PDBTitle: crystal structure of peptidase m16 inactive domain from pseudomonas2 fluorescens. northeast structural genomics target plr293l
15c3amjB_



100.0 15 PDB header:hydrolase
Chain: B: PDB Molecule:zinc peptidase inactive subunit;
PDBTitle: the crystal structure of the heterodimer of m16b peptidase from2 sphingomonas sp. a1
16c3cx5L_



100.0 16 PDB header:oxidoreductase
Chain: L: PDB Molecule:cytochrome b-c1 complex subunit 1, mitochondrial;
PDBTitle: structure of complex iii with bound cytochrome c in reduced2 state and definition of a minimal core interface for3 electron transfer.
17c3d3yA_



100.0 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a conserved protein from enterococcus faecalis2 v583
18d2fgea4



100.0 16 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
19d1ppja1



100.0 24 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
20c3cxhM_



100.0 15 PDB header:oxidoreductase
Chain: M: PDB Molecule:cytochrome b-c1 complex subunit 2, mitochondrial;
PDBTitle: structure of yeast complex iii with isoform-2 cytochrome c2 bound and definition of a minimal core interface for3 electron transfer.
21d1hr6b1



not modelled 100.0 21 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
22d1bcca1



not modelled 100.0 22 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
23d1hr6a1



not modelled 100.0 19 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
24d1q2la4



not modelled 100.0 17 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
25d1ppjb1



not modelled 100.0 18 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
26d1bccb1



not modelled 100.0 16 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
27d3cx5b1



not modelled 100.0 17 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
28d3cx5a1



not modelled 100.0 14 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
29d1q2la1



not modelled 99.9 15 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
30d1hr6b2



not modelled 99.9 10 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
31d1ppjb2



not modelled 99.9 7 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
32d1q2la2



not modelled 99.9 11 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
33c3ivlA_



not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative zinc protease;
PDBTitle: the crystal structure of the inactive peptidase domain of a putative2 zinc protease from bordetella parapertussis to 2.2a
34d1bcca2



not modelled 99.9 12 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
35d1hr6a2



not modelled 99.9 9 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
36d1ppja2



not modelled 99.8 12 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
37d2fgea2



not modelled 99.8 6 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
38d1bccb2



not modelled 99.8 9 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
39d3cx5a2



not modelled 99.8 11 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
40d2fgea1



not modelled 99.5 11 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
41d2fgea3



not modelled 99.4 11 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
42d1q2la3



not modelled 99.2 9 Fold:LuxS/MPP-like metallohydrolase
Superfamily:LuxS/MPP-like metallohydrolase
Family:MPP-like
43d1nsha_



not modelled 39.5 16 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
44c2rgiA_



not modelled 35.8 16 PDB header:metal binding protein
Chain: A: PDB Molecule:protein s100-a2;
PDBTitle: crystal structure of ca2+-free s100a2 at 1.6 a resolution
45d1a4pa_



not modelled 35.2 9 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
46d1qlsa_



not modelled 33.8 12 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
47d1g5ta_



not modelled 23.2 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
48c1ko7B_



not modelled 22.8 15 PDB header:transferase,hydrolase
Chain: B: PDB Molecule:hpr kinase/phosphatase;
PDBTitle: x-ray structure of the hpr kinase/phosphatase from2 staphylococcus xylosus at 1.95 a resolution
49c1g6uB_



not modelled 22.2 37 PDB header:de novo protein
Chain: B: PDB Molecule:domain swapped dimer;
PDBTitle: crystal structure of a domain swapped dimer
50d1ko7a1



not modelled 20.8 15 Fold:MurF and HprK N-domain-like
Superfamily:HprK N-terminal domain-like
Family:HPr kinase/phoshatase HprK N-terminal domain
51c2kfvA_



not modelled 20.5 23 PDB header:isomerase
Chain: A: PDB Molecule:fk506-binding protein 3;
PDBTitle: structure of the amino-terminal domain of human fk506-2 binding protein 3 / northeast structural genomics3 consortium target ht99a
52d1e8aa_



not modelled 20.3 12 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
53d2rdea1



not modelled 19.5 25 Fold:Split barrel-like
Superfamily:PilZ domain-like
Family:PilZ domain
54c2y5iF_



not modelled 19.2 16 PDB header:metal-binding protein
Chain: F: PDB Molecule:s100 calcium binding protein z;
PDBTitle: s100z from zebrafish in complex with calcium
55c1qpoA_



not modelled 17.9 10 PDB header:transferase
Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase;
PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis
56c3l7vA_



not modelled 17.4 13 PDB header:transcription
Chain: A: PDB Molecule:putative uncharacterized protein smu.1377c;
PDBTitle: crystal structure of a hypothetical protein smu.1377c from2 streptococcus mutans ua159
57d1ksoa_



not modelled 15.7 10 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
58c2uxsA_



not modelled 15.2 13 PDB header:hydrolase
Chain: A: PDB Molecule:inorganic pyrophosphatase;
PDBTitle: 2.7a crystal structure of inorganic pyrophosphatase (rv3628)2 from mycobacterium tuberculosis at ph 7.5
59d1knxa1



not modelled 14.2 14 Fold:MurF and HprK N-domain-like
Superfamily:HprK N-terminal domain-like
Family:HPr kinase/phoshatase HprK N-terminal domain
60d1g64b_



not modelled 13.5 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
61c3llkA_



not modelled 12.7 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:sulfhydryl oxidase 1;
PDBTitle: sulfhydryl oxidase fragment of human qsox1
62d3c1va1



not modelled 12.3 14 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
63d3cr5x1



not modelled 11.8 12 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
64d1zfsa1



not modelled 11.3 15 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
65c3fhkF_



not modelled 11.2 17 PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:upf0403 protein yphp;
PDBTitle: crystal structure of apc1446, b.subtilis yphp disulfide2 isomerase
66d1qlka_



not modelled 10.6 10 Fold:EF Hand-like
Superfamily:EF-hand
Family:S100 proteins
67c2pbrB_



not modelled 10.6 12 PDB header:transferase
Chain: B: PDB Molecule:thymidylate kinase;
PDBTitle: crystal structure of thymidylate kinase (aq_969) from aquifex aeolicus2 vf5
68d2prda_



not modelled 10.6 17 Fold:OB-fold
Superfamily:Inorganic pyrophosphatase
Family:Inorganic pyrophosphatase
69d3c7ba2



not modelled 10.5 12 Fold:Ferredoxin-like
Superfamily:Nitrite/Sulfite reductase N-terminal domain-like
Family:DsrA/DsrB N-terminal-domain-like
70c3ostA_



not modelled 10.1 8 PDB header:lipid binding protein
Chain: A: PDB Molecule:serine/threonine-protein kinase kcc4;
PDBTitle: structure of the kinase associated-1 (ka1) from kcc4p
71c3lv8A_



not modelled 9.6 12 PDB header:transferase
Chain: A: PDB Molecule:thymidylate kinase;
PDBTitle: 1.8 angstrom resolution crystal structure of a thymidylate kinase2 (tmk) from vibrio cholerae o1 biovar eltor str. n16961 in complex3 with tmp, thymidine-5'-diphosphate and adp
72d2ikba1



not modelled 9.4 17 Fold:Lysozyme-like
Superfamily:Lysozyme-like
Family:NMB1012-like
73d1zavz1



not modelled 9.2 21 Fold:Ribosomal protein L7/12, oligomerisation (N-terminal) domain
Superfamily:Ribosomal protein L7/12, oligomerisation (N-terminal) domain
Family:Ribosomal protein L7/12, oligomerisation (N-terminal) domain
74c1zawZ_



not modelled 9.2 21 PDB header:structural protein
Chain: Z: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form a
75c1zavZ_



not modelled 9.2 21 PDB header:structural protein
Chain: Z: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p21
76d1l7ba_



not modelled 9.0 22 Fold:BRCT domain
Superfamily:BRCT domain
Family:DNA ligase
77c1zawY_



not modelled 8.9 21 PDB header:structural protein
Chain: Y: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form a
78c1zawX_



not modelled 8.9 21 PDB header:structural protein
Chain: X: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form a
79d1pc2a_



not modelled 8.9 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
80c3pajA_



not modelled 8.8 16 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating;
PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961
81d1qpoa1



not modelled 8.7 10 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
82d1udea_



not modelled 8.6 15 Fold:OB-fold
Superfamily:Inorganic pyrophosphatase
Family:Inorganic pyrophosphatase
83d1v33a_



not modelled 8.6 17 Fold:Prim-pol domain
Superfamily:Prim-pol domain
Family:PriA-like
84c1knxF_



not modelled 8.6 12 PDB header:transferase/hydrolase
Chain: F: PDB Molecule:probable hpr(ser) kinase/phosphatase;
PDBTitle: hpr kinase/phosphatase from mycoplasma pneumoniae
85d1tuza_



not modelled 8.2 6 Fold:EF Hand-like
Superfamily:EF-hand
Family:EF-hand modules in multidomain proteins
86c2yw3E_



not modelled 8.2 11 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
87c3qf2B_



not modelled 8.0 11 PDB header:apoptosis
Chain: B: PDB Molecule:nacht, lrr and pyd domains-containing protein 3;
PDBTitle: crystal structure of nalp3 pyd
88d1u1qa_



not modelled 8.0 7 Fold:Ferredoxin-like
Superfamily:RNA-binding domain, RBD
Family:Canonical RBD
89c3dzzB_



not modelled 8.0 13 PDB header:transferase
Chain: B: PDB Molecule:putative pyridoxal 5'-phosphate-dependent c-s lyase;
PDBTitle: crystal structure of a putative plp-dependent aminotransferase2 (lbul_1103) from lactobacillus delbrueckii subsp. at 1.61 a3 resolution
90c3gnnA_



not modelled 7.9 21 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei
91d1kyqa2



not modelled 7.9 11 Fold:Siroheme synthase middle domains-like
Superfamily:Siroheme synthase middle domains-like
Family:Siroheme synthase middle domains-like
92c2ebuA_



not modelled 7.8 17 PDB header:replication
Chain: A: PDB Molecule:replication factor c subunit 1;
PDBTitle: solution structure of the brct domain from human2 replication factor c large subunit 1
93c1zawU_



not modelled 7.7 21 PDB header:structural protein
Chain: U: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form a
94c1zawW_



not modelled 7.7 21 PDB header:structural protein
Chain: W: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form a
95c1zawV_



not modelled 7.7 21 PDB header:structural protein
Chain: V: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form a
96c2b7pA_



not modelled 7.7 7 PDB header:transferase
Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori
97c2ld7A_



not modelled 7.6 7 PDB header:transcription
Chain: A: PDB Molecule:histone deacetylase complex subunit sap30;
PDBTitle: solution structure of the msin3a pah3-sap30 sid complex
98c1zaxZ_



not modelled 7.6 21 PDB header:structural protein
Chain: Z: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form b
99c1zaxV_



not modelled 7.5 21 PDB header:structural protein
Chain: V: PDB Molecule:50s ribosomal protein l7/l12;
PDBTitle: ribosomal protein l10-l12(ntd) complex, space group p212121,2 form b

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0