Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AEH1
DateThu Jan 5 11:23:20 GMT 2012
Unique Job IDc74bb06c30929ed5

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3rleA_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:golgi reassembly-stacking protein 2;
PDBTitle: crystal structure of grasp55 grasp domain (residues 7-208)
Confidence and coverage
Confidence: 99.9% Coverage: 42%
187 residues ( 42% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
324 residues ( 72%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGFGKALWRRTDKLGTEYV
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  IALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIAAGPVANFIFAIFAYWLVF
Secondary structure 
SS confidence 
Disorder 
??????????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  IIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETPDWDAVRLQLVDKIGDESTTI
Secondary structure 
SS confidence 
Disorder  ??
??
?
?
?
????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  TVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPRGPQIEPVLENVQPNSAASKAGL
Secondary structure 
SS confidence 
Disorder 
?
?????????????
?
???
?
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  QAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEIERQGSPLSLTLIPESKPGNGKAIG
Secondary structure 
SS confidence 
Disorder 
??
?????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  FVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKTWQLMKLTVSMLGKLITGDVKLNNLSG
Secondary structure 
SS confidence 
Disorder 
??????????????
?
??
?
????????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  PISIAKGAGMTAELGVVYYLPFLALISVNLGIINLFPLPVLDGGHLLFLAIEKIKGGPVS
Secondary structure 
SS confidence 
Disorder  ????????
Disorder confidence 
 
   .........430.........440.........450
Sequence  ERVQDFCYRIGSILLVLLMGLALFNDFSRL
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3rle chain A

3D model

Region: 130 - 402
Aligned: 187
Modelled: 188
Confidence: 99.9%
Identity: 19%
PDB header:membrane protein
Chain: A: PDB Molecule:golgi reassembly-stacking protein 2;
PDBTitle: crystal structure of grasp55 grasp domain (residues 7-208)

Phyre2

PDB 3pv5 chain B

3D model

Region: 120 - 287
Aligned: 167
Modelled: 168
Confidence: 99.9%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:degq;
PDBTitle: structure of legionella fallonii degq (n189g/p190g variant)

Phyre2

PDB 4a8a chain I

3D model

Region: 129 - 287
Aligned: 153
Modelled: 159
Confidence: 99.8%
Identity: 18%
PDB header:hydrolase/hydrolase
Chain: I: PDB Molecule:periplasmic ph-dependent serine endoprotease degq;
PDBTitle: asymmetric cryo-em reconstruction of e. coli degq 12-mer in complex2 with lysozyme

Phyre2

PDB 1p1d chain A

3D model

Region: 125 - 281
Aligned: 156
Modelled: 157
Confidence: 99.8%
Identity: 17%
PDB header:protein binding
Chain: A: PDB Molecule:glutamate receptor interacting protein;
PDBTitle: structural insights into the inter-domain chaperoning of2 tandem pdz domains in glutamate receptor interacting3 proteins

Phyre2

PDB 2ka9 chain A

3D model

Region: 123 - 281
Aligned: 157
Modelled: 157
Confidence: 99.7%
Identity: 14%
PDB header:cell adhesion
Chain: A: PDB Molecule:disks large homolog 4;
PDBTitle: solution structure of psd-95 pdz12 complexed with cypin2 peptide

Phyre2

PDB 2qt5 chain A

3D model

Region: 125 - 279
Aligned: 153
Modelled: 155
Confidence: 99.7%
Identity: 22%
PDB header:peptide binding protein
Chain: A: PDB Molecule:glutamate receptor-interacting protein 1;
PDBTitle: crystal structure of grip1 pdz12 in complex with the fras12 peptide

Phyre2

PDB 3b4r chain B

3D model

Region: 8 - 444
Aligned: 148
Modelled: 148
Confidence: 99.7%
Identity: 43%
PDB header:hydrolase
Chain: B: PDB Molecule:putative zinc metalloprotease mj0392;
PDBTitle: site-2 protease from methanocaldococcus jannaschii

Phyre2

PDB 3r0h chain A

3D model

Region: 123 - 278
Aligned: 148
Modelled: 156
Confidence: 99.7%
Identity: 14%
PDB header:peptide binding protein
Chain: A: PDB Molecule:inactivation-no-after-potential d protein;
PDBTitle: structure of inad pdz45 in complex with ng2 peptide

Phyre2

PDB 1w9q chain B

3D model

Region: 129 - 276
Aligned: 132
Modelled: 133
Confidence: 99.6%
Identity: 14%
PDB header:cell adhesion
Chain: B: PDB Molecule:syntenin 1;
PDBTitle: crystal structure of the pdz tandem of human syntenin in2 complex with tnefaf peptide

Phyre2

PDB 1u3b chain A

3D model

Region: 123 - 278
Aligned: 142
Modelled: 143
Confidence: 99.6%
Identity: 13%
PDB header:protein transport
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding,
PDBTitle: auto-inhibition mechanism of x11s/mints family scaffold2 proteins revealed by the closed conformation of the tandem3 pdz domains

Phyre2

PDB 2xkx chain B

3D model

Region: 127 - 281
Aligned: 153
Modelled: 155
Confidence: 99.5%
Identity: 14%
PDB header:structural protein
Chain: B: PDB Molecule:disks large homolog 4;
PDBTitle: single particle analysis of psd-95 in negative stain

Phyre2

PDB 2p3w chain B

3D model

Region: 219 - 300
Aligned: 80
Modelled: 82
Confidence: 99.4%
Identity: 31%
PDB header:protein binding
Chain: B: PDB Molecule:probable serine protease htra3;
PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv)

Phyre2

PDB 1lcy chain A domain 1

3D model

Region: 219 - 293
Aligned: 73
Modelled: 75
Confidence: 99.3%
Identity: 29%
Fold: PDZ domain-like
Superfamily: PDZ domain-like
Family: HtrA-like serine proteases

Phyre2

PDB 3i18 chain A

3D model

Region: 220 - 304
Aligned: 84
Modelled: 85
Confidence: 99.3%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo2051 protein;
PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b

Phyre2

PDB 1lcy chain A

3D model

Region: 219 - 293
Aligned: 73
Modelled: 75
Confidence: 99.3%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:htra2 serine protease;
PDBTitle: crystal structure of the mitochondrial serine protease htra2

Phyre2

PDB 2z9i chain A domain 1

3D model

Region: 212 - 292
Aligned: 81
Modelled: 81
Confidence: 99.3%
Identity: 26%
Fold: PDZ domain-like
Superfamily: PDZ domain-like
Family: HtrA-like serine proteases

Phyre2

PDB 2kl1 chain A

3D model

Region: 219 - 305
Aligned: 85
Modelled: 87
Confidence: 99.3%
Identity: 28%
PDB header:protein binding
Chain: A: PDB Molecule:ylbl protein;
PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c

Phyre2

PDB 2zpm chain A

3D model

Region: 224 - 308
Aligned: 80
Modelled: 85
Confidence: 99.3%
Identity: 89%
PDB header:hydrolase
Chain: A: PDB Molecule:regulator of sigma e protease;
PDBTitle: crystal structure analysis of pdz domain b

Phyre2

PDB 3stj chain C

3D model

Region: 219 - 292
Aligned: 74
Modelled: 74
Confidence: 99.3%
Identity: 28%
PDB header:hydrolase
Chain: C: PDB Molecule:protease degq;
PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli

Phyre2

PDB 2joa chain A

3D model

Region: 219 - 293
Aligned: 73
Modelled: 75
Confidence: 99.2%
Identity: 21%
PDB header:protein binding
Chain: A: PDB Molecule:serine protease htra1;
PDBTitle: htra1 bound to an optimized peptide: nmr assignment of pdz2 domain and ligand resonances

Phyre2
1
c3rleA_
2
c3pv5B_
3
c4a8aI_
4
c1p1dA_
5
c2ka9A_
6
c2qt5A_
7
c3b4rB_
8
c3r0hA_
9
c1w9qB_
10
c1u3bA_
11
c2xkxB_
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c2p3wB_
13
d1lcya1
14
c3i18A_
15
c1lcyA_
16
d2z9ia1
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c2kl1A_
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c2zpmA_
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c3stjC_
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c2joaA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3rleA_
99.9 19 PDB header:membrane protein
Chain: A: PDB Molecule:golgi reassembly-stacking protein 2;
PDBTitle: crystal structure of grasp55 grasp domain (residues 7-208)
2c3pv5B_
99.9 16 PDB header:hydrolase
Chain: B: PDB Molecule:degq;
PDBTitle: structure of legionella fallonii degq (n189g/p190g variant)
3c4a8aI_
99.8 18 PDB header:hydrolase/hydrolase
Chain: I: PDB Molecule:periplasmic ph-dependent serine endoprotease degq;
PDBTitle: asymmetric cryo-em reconstruction of e. coli degq 12-mer in complex2 with lysozyme
4c1p1dA_
99.8 17 PDB header:protein binding
Chain: A: PDB Molecule:glutamate receptor interacting protein;
PDBTitle: structural insights into the inter-domain chaperoning of2 tandem pdz domains in glutamate receptor interacting3 proteins
5c2ka9A_
99.7 14 PDB header:cell adhesion
Chain: A: PDB Molecule:disks large homolog 4;
PDBTitle: solution structure of psd-95 pdz12 complexed with cypin2 peptide
6c2qt5A_
99.7 22 PDB header:peptide binding protein
Chain: A: PDB Molecule:glutamate receptor-interacting protein 1;
PDBTitle: crystal structure of grip1 pdz12 in complex with the fras12 peptide
7c3b4rB_
99.7 43 PDB header:hydrolase
Chain: B: PDB Molecule:putative zinc metalloprotease mj0392;
PDBTitle: site-2 protease from methanocaldococcus jannaschii
8c3r0hA_
99.7 14 PDB header:peptide binding protein
Chain: A: PDB Molecule:inactivation-no-after-potential d protein;
PDBTitle: structure of inad pdz45 in complex with ng2 peptide
9c1w9qB_
99.6 14 PDB header:cell adhesion
Chain: B: PDB Molecule:syntenin 1;
PDBTitle: crystal structure of the pdz tandem of human syntenin in2 complex with tnefaf peptide
10c1u3bA_
99.6 13 PDB header:protein transport
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding,
PDBTitle: auto-inhibition mechanism of x11s/mints family scaffold2 proteins revealed by the closed conformation of the tandem3 pdz domains
11c2xkxB_
99.5 14 PDB header:structural protein
Chain: B: PDB Molecule:disks large homolog 4;
PDBTitle: single particle analysis of psd-95 in negative stain
12c2p3wB_
99.4 31 PDB header:protein binding
Chain: B: PDB Molecule:probable serine protease htra3;
PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv)
13d1lcya1
99.3 29 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
14c3i18A_
99.3 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo2051 protein;
PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b
15c1lcyA_
99.3 27 PDB header:hydrolase
Chain: A: PDB Molecule:htra2 serine protease;
PDBTitle: crystal structure of the mitochondrial serine protease htra2
16d2z9ia1
99.3 26 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
17c2kl1A_
99.3 28 PDB header:protein binding
Chain: A: PDB Molecule:ylbl protein;
PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c
18c2zpmA_
99.3 89 PDB header:hydrolase
Chain: A: PDB Molecule:regulator of sigma e protease;
PDBTitle: crystal structure analysis of pdz domain b
19c3stjC_
99.3 28 PDB header:hydrolase
Chain: C: PDB Molecule:protease degq;
PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli
20c2joaA_
99.2 21 PDB header:protein binding
Chain: A: PDB Molecule:serine protease htra1;
PDBTitle: htra1 bound to an optimized peptide: nmr assignment of pdz2 domain and ligand resonances
21c3pv4A_
not modelled 99.2 27 PDB header:hydrolase
Chain: A: PDB Molecule:degq;
PDBTitle: structure of legionella fallonii degq (delta-pdz2 variant)
22c2kjpA_
not modelled 99.2 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein ylbl;
PDBTitle: solution structure of protein ylbl (bsu15050) from bacillus2 subtilis, northeast structural genomics consortium target3 sr713a
23c2zplA_
not modelled 99.2 99 PDB header:hydrolase
Chain: A: PDB Molecule:regulator of sigma e protease;
PDBTitle: crystal structure analysis of pdz domain a
24d1fc6a3
not modelled 99.1 24 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:Tail specific protease PDZ domain
25d2hgaa1
not modelled 99.1 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:MTH1368 C-terminal domain-like
26d2i4sa1
not modelled 99.1 23 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:EpsC C-terminal domain-like
27c3qo6B_
not modelled 99.1 25 PDB header:photosynthesis
Chain: B: PDB Molecule:protease do-like 1, chloroplastic;
PDBTitle: crystal structure analysis of the plant protease deg1
28d1ky9b2
not modelled 99.0 27 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
29d2i6va1
not modelled 99.0 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:EpsC C-terminal domain-like
30c3gdsA_
not modelled 99.0 23 PDB header:hydrolase/hydrolase activator
Chain: A: PDB Molecule:protease degs;
PDBTitle: crystal structure of degs h198p/d320a mutant modified by dfp in2 complex with dnrdgnvyyf peptide
31d1ky9a1
not modelled 98.9 31 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
32c1z87A_
not modelled 98.9 22 PDB header:protein binding
Chain: A: PDB Molecule:alpha-1-syntrophin;
PDBTitle: solution structure of the split ph-pdz supramodule of alpha-2 syntrophin
33c2eaqA_
not modelled 98.9 15 PDB header:metal binding protein
Chain: A: PDB Molecule:lim domain only protein 7;
PDBTitle: crystal structure of pdz domain of kiaa0858 (lim), ms07932 from homo sapiens
34d1w9ea1
not modelled 98.9 23 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
35c1ky9A_
not modelled 98.9 31 PDB header:hydrolase
Chain: A: PDB Molecule:protease do;
PDBTitle: crystal structure of degp (htra)
36d1qaua_
not modelled 98.9 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
37d1x5qa1
not modelled 98.8 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
38c2krgA_
not modelled 98.8 25 PDB header:signaling protein
Chain: A: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf1;
PDBTitle: solution structure of human sodium/ hydrogen exchange2 regulatory factor 1(150-358)
39c2kjdA_
not modelled 98.8 25 PDB header:signaling protein
Chain: A: PDB Molecule:sodium/hydrogen exchange regulatory cofactor nhe-
PDBTitle: solution structure of extended pdz2 domain from nherf1 (150-2 270)
40c3diwB_
not modelled 98.8 24 PDB header:signaling protein/cell adhesion
Chain: B: PDB Molecule:tax1-binding protein 3;
PDBTitle: c-terminal beta-catenin bound tip-1 structure
41d1sota1
not modelled 98.8 26 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:HtrA-like serine proteases
42d1ozia_
not modelled 98.8 21 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
43d1wh1a_
not modelled 98.8 24 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
44d1m5za_
not modelled 98.8 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
45d1wifa_
not modelled 98.8 19 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
46c2vsvB_
not modelled 98.8 18 PDB header:protein-binding
Chain: B: PDB Molecule:rhophilin-2;
PDBTitle: crystal structure of the pdz domain of human rhophilin-2
47c3eggC_
not modelled 98.8 30 PDB header:hydrolase
Chain: C: PDB Molecule:spinophilin;
PDBTitle: crystal structure of a complex between protein phosphatase 1 alpha2 (pp1) and the pp1 binding and pdz domains of spinophilin
48c2vwrA_
not modelled 98.8 17 PDB header:protein-binding
Chain: A: PDB Molecule:ligand of numb protein x 2;
PDBTitle: crystal structure of the second pdz domain of numb-binding2 protein 2
49c2he4A_
not modelled 98.8 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf2;
PDBTitle: the crystal structure of the second pdz domain of human2 nherf-2 (slc9a3r2) interacting with a mode 1 pdz binding3 motif
50d1wfga_
not modelled 98.7 19 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
51d1p1da2
not modelled 98.7 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
52d1q3oa_
not modelled 98.7 31 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
53c3l4fD_
not modelled 98.7 25 PDB header:signaling protein/protein binding
Chain: D: PDB Molecule:sh3 and multiple ankyrin repeat domains protein
PDBTitle: crystal structure of betapix coiled-coil domain and shank2 pdz complex
54c3shuB_
not modelled 98.7 27 PDB header:cell adhesion
Chain: B: PDB Molecule:tight junction protein zo-1;
PDBTitle: crystal structure of zo-1 pdz3
55d1pdra_
not modelled 98.7 14 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
56c2eehA_
not modelled 98.7 30 PDB header:metal binding protein
Chain: A: PDB Molecule:pdz domain-containing protein 7;
PDBTitle: solution structure of first pdz domain of pdz domain2 containing protein 7
57c2komA_
not modelled 98.7 26 PDB header:signaling protein
Chain: A: PDB Molecule:partitioning defective 3 homolog;
PDBTitle: solution structure of humar par-3b pdz2 (residues 451-549)
58d1ueqa_
not modelled 98.7 19 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
59d1rgwa_
not modelled 98.7 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
60d1uf1a_
not modelled 98.7 26 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
61c2egkC_
not modelled 98.7 23 PDB header:protein binding
Chain: C: PDB Molecule:general receptor for phosphoinositides 1-
PDBTitle: crystal structure of tamalin pdz-intrinsic ligand fusion2 protein
62c2q3gA_
not modelled 98.7 21 PDB header:structural genomics
Chain: A: PDB Molecule:pdz and lim domain protein 7;
PDBTitle: structure of the pdz domain of human pdlim7 bound to a c-2 terminal extension from human beta-tropomyosin
63d1q7xa_
not modelled 98.7 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
64d1g9oa_
not modelled 98.7 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
65c2iwnA_
not modelled 98.7 27 PDB header:signaling protein
Chain: A: PDB Molecule:multiple pdz domain protein;
PDBTitle: 3rd pdz domain of multiple pdz domain protein mpdz (casp2 target)
66d2f5ya1
not modelled 98.7 19 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
67d1d5ga_
not modelled 98.7 29 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
68d2f0aa1
not modelled 98.7 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
69d1uhpa_
not modelled 98.7 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
70d1tp5a1
not modelled 98.7 14 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
71d1be9a_
not modelled 98.7 14 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
72c2gzvA_
not modelled 98.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:prkca-binding protein;
PDBTitle: the cystal structure of the pdz domain of human pick1 (casp target)
73c2jxoA_
not modelled 98.7 25 PDB header:protein binding
Chain: A: PDB Molecule:ezrin-radixin-moesin-binding phosphoprotein 50;
PDBTitle: structure of the second pdz domain of nherf-1
74c3khfA_
not modelled 98.6 29 PDB header:transferase
Chain: A: PDB Molecule:microtubule-associated serine/threonine-protein
PDBTitle: the crystal structure of the pdz domain of human microtubule2 associated serine/threonine kinase 3 (mast3)
75c2jilA_
not modelled 98.6 27 PDB header:membrane protein
Chain: A: PDB Molecule:glutamate receptor interacting protein-1;
PDBTitle: crystal structure of 2nd pdz domain of glutamate receptor2 interacting protein-1 (grip1)
76d1t2ma1
not modelled 98.6 28 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
77c2v90E_
not modelled 98.6 21 PDB header:protein-binding
Chain: E: PDB Molecule:pdz domain-containing protein 3;
PDBTitle: crystal structure of the 3rd pdz domain of intestine- and2 kidney-enriched pdz domain ikepp (pdzd3)
78c3k1rA_
not modelled 98.6 20 PDB header:structural protein
Chain: A: PDB Molecule:harmonin;
PDBTitle: structure of harmonin npdz1 in complex with the sam-pbm of2 sans
79d2fe5a1
not modelled 98.6 23 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
80c2qktB_
not modelled 98.6 20 PDB header:peptide binding protein
Chain: B: PDB Molecule:inactivation-no-after-potential d protein;
PDBTitle: crystal structure of the 5th pdz domain of inad
81c3qikA_
not modelled 98.6 19 PDB header:hydrolase regulator
Chain: A: PDB Molecule:phosphatidylinositol 3,4,5-trisphosphate-dependent rac
PDBTitle: crystal structure of the first pdz domain of prex1
82c2e7kA_
not modelled 98.6 24 PDB header:membrane protein
Chain: A: PDB Molecule:maguk p55 subfamily member 2;
PDBTitle: solution structure of the pdz domain from human maguk p552 subfamily member 2
83c2ogpA_
not modelled 98.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:partitioning-defective 3 homolog;
PDBTitle: solution structure of the second pdz domain of par-3
84c2k1zA_
not modelled 98.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:partitioning-defective 3 homolog;
PDBTitle: solution structure of par-3 pdz3
85c2jikB_
not modelled 98.6 26 PDB header:membrane protein
Chain: B: PDB Molecule:synaptojanin-2 binding protein;
PDBTitle: crystal structure of pdz domain of synaptojanin-2 binding2 protein
86d1va8a1
not modelled 98.6 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
87c2jreA_
not modelled 98.6 30 PDB header:de novo protein
Chain: A: PDB Molecule:c60-1 pdz domain peptide;
PDBTitle: c60-1, a pdz domain designed using statistical coupling2 analysis
88d1ihja_
not modelled 98.6 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
89c2d92A_
not modelled 98.6 21 PDB header:protein binding
Chain: A: PDB Molecule:inad-like protein;
PDBTitle: solution structure of the fifth pdz domain of inad-like2 protein
90c2fneB_
not modelled 98.6 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:multiple pdz domain protein;
PDBTitle: the crystal structure of the 13th pdz domain of mpdz
91c2dkrA_
not modelled 98.6 19 PDB header:protein transport
Chain: A: PDB Molecule:lin-7 homolog b;
PDBTitle: solution structure of the pdz domain from human lin-72 homolog b
92c2edzA_
not modelled 98.6 26 PDB header:signaling protein
Chain: A: PDB Molecule:pdz domain-containing protein 1;
PDBTitle: solution structures of the pdz domain of mus musculus pdz2 domain-containing protein 1
93d1ry4a_
not modelled 98.6 17 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
94c2o2tB_
not modelled 98.6 16 PDB header:structural protein
Chain: B: PDB Molecule:multiple pdz domain protein;
PDBTitle: the crystal structure of the 1st pdz domain of mpdz
95d1wjla_
not modelled 98.6 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
96c2omjA_
not modelled 98.6 29 PDB header:cell adhesion
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12;
PDBTitle: solution structure of larg pdz domain
97c2qg1A_
not modelled 98.6 21 PDB header:signaling protein
Chain: A: PDB Molecule:multiple pdz domain protein;
PDBTitle: crystal structure of the 11th pdz domain of mpdz (mupp1)
98c2d90A_
not modelled 98.6 19 PDB header:protein binding
Chain: A: PDB Molecule:pdz domain containing protein 1;
PDBTitle: solution structure of the third pdz domain of pdz domain2 containing protein 1
99c3qglD_
not modelled 98.6 32 PDB header:protein binding
Chain: D: PDB Molecule:sorting nexin-27;
PDBTitle: crystal structure of pdz domain of sorting nexin 27 (snx27) in complex2 with the eseskv peptide corresponding to the c-terminal tail of girk3
100d1whaa_
not modelled 98.6 24 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
101c2dmzA_
not modelled 98.6 33 PDB header:protein binding
Chain: A: PDB Molecule:inad-like protein;
PDBTitle: solution structure of the third pdz domain of human inad-2 like protein
102c2dluA_
not modelled 98.6 24 PDB header:protein binding
Chain: A: PDB Molecule:inad-like protein;
PDBTitle: solution structure of the second pdz domain of human inad-2 like protein
103d2byga1
not modelled 98.6 21 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
104d1kwaa_
not modelled 98.6 14 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
105d2cssa1
not modelled 98.6 18 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
106c3hpmA_
not modelled 98.6 23 PDB header:protein binding
Chain: A: PDB Molecule:protein interacting with prkca 1;
PDBTitle: oxidized dimeric pick1 pdz c46g mutant in complex with the carboxyl2 tail peptide of glur2
107d1p1da1
not modelled 98.6 32 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
108d1wf8a1
not modelled 98.6 32 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
109d1whda_
not modelled 98.6 17 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
110c2i04B_
not modelled 98.6 21 PDB header:peptide binding protein
Chain: B: PDB Molecule:membrane-associated guanylate kinase, ww and pdz
PDBTitle: x-ray crystal structure of magi-1 pdz1 bound to the c-2 terminal peptide of hpv18 e6
111c2z17A_
not modelled 98.6 24 PDB header:protein binding
Chain: A: PDB Molecule:pleckstrin homology sec7 and coiled-coil domains-
PDBTitle: crystal sturcture of pdz domain from human pleckstrin2 homology, sec7
112c2v1wB_
not modelled 98.6 21 PDB header:structural protein
Chain: B: PDB Molecule:pdz and lim domain protein 4;
PDBTitle: crystal structure of human lim protein ril (pdlim4) pdz2 domain bound to the c-terminal peptide of human alpha-3 actinin-1
113d1n7ea_
not modelled 98.6 20 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
114d1um1a_
not modelled 98.6 26 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
115c2dm8A_
not modelled 98.6 24 PDB header:protein binding
Chain: A: PDB Molecule:inad-like protein;
PDBTitle: solution structure of the eighth pdz domain of human inad-2 like protein
116d1ujda_
not modelled 98.6 22 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
117d1wf7a_
not modelled 98.6 16 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
118c3shwA_
not modelled 98.6 28 PDB header:cell adhesion
Chain: A: PDB Molecule:tight junction protein zo-1;
PDBTitle: crystal structure of zo-1 pdz3-sh3-guk supramodule complex with2 connexin-45 peptide
119d1vaea_
not modelled 98.6 21 Fold:PDZ domain-like
Superfamily:PDZ domain-like
Family:PDZ domain
120c3b76A_
not modelled 98.6 28 PDB header:ligase
Chain: A: PDB Molecule:e3 ubiquitin-protein ligase lnx;
PDBTitle: crystal structure of the third pdz domain of human ligand-of-numb2 protein-x (lnx1) in complex with the c-terminal peptide from the3 coxsackievirus and adenovirus receptor

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0