Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	C	W	Q	I	L	E	I	E	S	T	T	Q	I	D	I	I	R	Q	A	Y	L	A	R	L	P	L	C	H	P	E	T	D	P	Q	G	F	K	A	L	R	Q	A	Y	E	E	A	L	R	L	A	V	N	P	V	E	E	A
Secondary structure
SS confidence
Disorder		?	?	?									?	?	?	?																		?	?	?																			?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	D	E	E	K	D	A	A	A	E	H	E	I	L	R	A	F	R	T	L	L	D	S	E	S	D	R	F	Q	P	S	A	W	Q	K	F	I	Q	Q	L	N	T	W	N	M	E	D	V	D	Q	L	R	W	P	L	C	A	I	A	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?											?	?	?		?	?	?	?													?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	A	R	Y	L	S	L	N	C	A	S	L	L	A	E	R	L	N	W	H	S	F	N	D	S	E	G	M	D	E	E	E	R	E	A	F	L	E	A	I	Q	A	G	D	C	F	D	F	L	S	L	L	E	Y	P	I	A	L	Q	N
Secondary structure
SS confidence
Disorder																									?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	T	V	E	Y	Y	F	A	L	E	R	C	C	R	Y	H	P	D	Y	V	T	A	F	L	A	M	E	G	P	W	L	I	P	D	D	A	K	L	H	R	K	L	L	R	W	Y	S	S	V	Q	T	G	M	A	E	L	I	P	V	A
Secondary structure
SS confidence
Disorder																																																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Q	Q	W	Q	T	E	E	P	E	S	E	D	A	R	Y	Y	L	C	A	Q	R	L	Y	C	G	E	G	E	S	L	L	A	D	L	C	A	Y	W	E	S	Y	P	S	T	Q	A	D	N	L	L	L	Q	W	S	K	R	H	C	P	D
Secondary structure
SS confidence
Disorder							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	F	A	L	L	V	M	V	I	E	A	R	S	M	V	D	A	Q	G	Q	P	L	K	Y	V	P	G	E	S	A	R	T	R	L	L	W	A	E	I	L	H	S	G	K	L	S	P	L	G	Q	S	F	I	E	S	L	F	F	K	R
Secondary structure
SS confidence
Disorder											?	?				?	?																								?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		K	A	W	A	W	W	K	S	R	V	G	S	E	T	E	Q	D	S	P	F	L	D	L	Y	R	V	A	E	Q	V	V	L	E	A	F	P	K	Q	E	M	L	A	R	L	N	T	R	L	E	G	G	D	A	H	P	L	E	A	I	V
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?	?																					?									?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		T	R	M	L	L	T	K	V	K	L	E	P	E	D	E	D	V	D	E	P	T	P	E	N	H	E	E	K	N	D	E	G	E	K	P	Q	S	I	T	S	I	I	K	I	S	L	T	V	L	V	I	G	Y	A	L	G	K	I	A	M
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.
Sequence		L	F	S
Secondary structure
SS confidence
Disorder			?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2pf4 chain E Region: 2 - 47 Aligned: 45 Modelled: 45 Confidence: 98.8% Identity: 27% PDB header:hydrolase regulator/viral protein Chain: E: PDB Molecule:small t antigen; PDBTitle: crystal structure of the full-length simian virus 40 small t antigen2 complexed with the protein phosphatase 2a aalpha subunit Phyre2 PDB 1gh6 chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.6% Identity: 24% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 1fpo chain A Region: 3 - 47 Aligned: 45 Modelled: 45 Confidence: 98.5% Identity: 11% PDB header:chaperone Chain: A: PDB Molecule:chaperone protein hscb; PDBTitle: hsc20 (hscb), a j-type co-chaperone from e. coli Phyre2 PDB 3hho chain A Region: 3 - 47 Aligned: 45 Modelled: 45 Confidence: 98.5% Identity: 11% PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb homolog; PDBTitle: chaperone hscb from vibrio cholerae Phyre2 PDB 3apq chain B Region: 1 - 47 Aligned: 47 Modelled: 47 Confidence: 98.5% Identity: 30% PDB header:oxidoreductase Chain: B: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of j-trx1 fragment of erdj5 Phyre2 PDB 2ctq chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.5% Identity: 26% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 12; PDBTitle: solution structure of j-domain from human dnaj subfamily c2 menber 12 Phyre2 PDB 3bvo chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.5% Identity: 13% PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb, mitochondrial precursor; PDBTitle: crystal structure of human co-chaperone protein hscb Phyre2 PDB 2lgw chain A Region: 1 - 47 Aligned: 47 Modelled: 47 Confidence: 98.5% Identity: 32% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 2; PDBTitle: solution structure of the j domain of hsj1a Phyre2 PDB 2ys8 chain A Region: 1 - 47 Aligned: 47 Modelled: 47 Confidence: 98.4% Identity: 30% PDB header:protein binding Chain: A: PDB Molecule:rab-related gtp-binding protein rabj; PDBTitle: solution structure of the dnaj-like domain from human ras-2 associated protein rap1 Phyre2 PDB 2kqx chain A Region: 1 - 47 Aligned: 47 Modelled: 47 Confidence: 98.4% Identity: 26% PDB header:chaperone binding protein Chain: A: PDB Molecule:curved dna-binding protein; PDBTitle: nmr structure of the j-domain (residues 2-72) in the2 escherichia coli cbpa Phyre2 PDB 1faf chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.4% Identity: 17% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 2ctw chain A Region: 1 - 47 Aligned: 47 Modelled: 47 Confidence: 98.4% Identity: 23% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 5; PDBTitle: solution structure of j-domain from mouse dnaj subfamily c2 menber 5 Phyre2 PDB 1iur chain A Region: 1 - 66 Aligned: 63 Modelled: 66 Confidence: 98.3% Identity: 16% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 2l6l chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.3% Identity: 28% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 24; PDBTitle: solution structure of human j-protein co-chaperone, dph4 Phyre2 PDB 2ctr chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.3% Identity: 22% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 9; PDBTitle: solution structure of j-domain from human dnaj subfamily b2 menber 9 Phyre2 PDB 2dmx chain A Region: 1 - 47 Aligned: 47 Modelled: 47 Confidence: 98.3% Identity: 28% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 8; PDBTitle: solution structure of the j domain of dnaj homolog2 subfamily b member 8 Phyre2 PDB 2yua chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.2% Identity: 28% PDB header:chaperone Chain: A: PDB Molecule:williams-beuren syndrome chromosome region 18 PDBTitle: solution structure of the dnaj domain from human williams-2 beuren syndrome chromosome region 18 protein Phyre2 PDB 1wjz chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.2% Identity: 28% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 2qsa chain A Region: 1 - 47 Aligned: 47 Modelled: 47 Confidence: 98.2% Identity: 26% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog dnj-2; PDBTitle: crystal structure of j-domain of dnaj homolog dnj-2 precursor from2 c.elegans. Phyre2 PDB 1xbl chain A Region: 2 - 47 Aligned: 46 Modelled: 46 Confidence: 98.2% Identity: 30% Fold: Long alpha-hairpin Superfamily: Chaperone J-domain Family: Chaperone J-domain Phyre2 PDB 3bee chain B Region: 223 - 283 Aligned: 61 Modelled: 60 Confidence: 87.0% Identity: 15% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative yfre protein; PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus Phyre2 PDB 3urz chain B Region: 212 - 295 Aligned: 84 Modelled: 83 Confidence: 75.4% Identity: 17% PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution Phyre2 PDB 2e2e chain A Region: 176 - 283 Aligned: 108 Modelled: 108 Confidence: 57.3% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 Phyre2 PDB 2r5s chain B Region: 149 - 283 Aligned: 134 Modelled: 134 Confidence: 57.0% Identity: 15% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp0806; PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633 Phyre2 1 c2pf4E_ 2 d1gh6a_ 3 c1fpoA_ 4 c3hhoA_ 5 c3apqB_ 6 c2ctqA_ 7 c3bvoA_ 8 c2lgwA_ 9 c2ys8A_ 10 c2kqxA_ 11 d1fafa_ 12 c2ctwA_ 13 d1iura_ 14 c2l6lA_ 15 c2ctrA_ 16 c2dmxA_ 17 c2yuaA_ 18 d1wjza_ 19 c2qsaA_ 20 d1xbla_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 c3beeB_ 37 38 c3urzB_ 39 40 c2e2eA_ 41 c2r5sB_ 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2pf4E_ 98.8 27 PDB header:hydrolase regulator/viral protein Chain: E: PDB Molecule:small t antigen; PDBTitle: crystal structure of the full-length simian virus 40 small t antigen2 complexed with the protein phosphatase 2a aalpha subunit 2 d1gh6a_ 98.6 24 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 3 c1fpoA_ 98.5 11 PDB header:chaperone Chain: A: PDB Molecule:chaperone protein hscb; PDBTitle: hsc20 (hscb), a j-type co-chaperone from e. coli 4 c3hhoA_ 98.5 11 PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb homolog; PDBTitle: chaperone hscb from vibrio cholerae 5 c3apqB_ 98.5 30 PDB header:oxidoreductase Chain: B: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of j-trx1 fragment of erdj5 6 c2ctqA_ 98.5 26 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 12; PDBTitle: solution structure of j-domain from human dnaj subfamily c2 menber 12 7 c3bvoA_ 98.5 13 PDB header:chaperone Chain: A: PDB Molecule:co-chaperone protein hscb, mitochondrial precursor; PDBTitle: crystal structure of human co-chaperone protein hscb 8 c2lgwA_ 98.5 32 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 2; PDBTitle: solution structure of the j domain of hsj1a 9 c2ys8A_ 98.4 30 PDB header:protein binding Chain: A: PDB Molecule:rab-related gtp-binding protein rabj; PDBTitle: solution structure of the dnaj-like domain from human ras-2 associated protein rap1 10 c2kqxA_ 98.4 26 PDB header:chaperone binding protein Chain: A: PDB Molecule:curved dna-binding protein; PDBTitle: nmr structure of the j-domain (residues 2-72) in the2 escherichia coli cbpa 11 d1fafa_ 98.4 17 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 12 c2ctwA_ 98.4 23 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 5; PDBTitle: solution structure of j-domain from mouse dnaj subfamily c2 menber 5 13 d1iura_ 98.3 16 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 14 c2l6lA_ 98.3 28 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 24; PDBTitle: solution structure of human j-protein co-chaperone, dph4 15 c2ctrA_ 98.3 22 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 9; PDBTitle: solution structure of j-domain from human dnaj subfamily b2 menber 9 16 c2dmxA_ 98.3 28 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 8; PDBTitle: solution structure of the j domain of dnaj homolog2 subfamily b member 8 17 c2yuaA_ 98.2 28 PDB header:chaperone Chain: A: PDB Molecule:williams-beuren syndrome chromosome region 18 PDBTitle: solution structure of the dnaj domain from human williams-2 beuren syndrome chromosome region 18 protein 18 d1wjza_ 98.2 28 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 19 c2qsaA_ 98.2 26 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog dnj-2; PDBTitle: crystal structure of j-domain of dnaj homolog dnj-2 precursor from2 c.elegans. 20 d1xbla_ 98.2 30 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 21 c2ctpA_ not modelled 98.2 26 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily b member 12; PDBTitle: solution structure of j-domain from human dnaj subfamily b2 menber 12 22 d1hdja_ not modelled 98.2 28 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 23 c2o37A_ not modelled 98.2 17 PDB header:chaperone Chain: A: PDB Molecule:protein sis1; PDBTitle: j-domain of sis1 protein, hsp40 co-chaperone from2 saccharomyces cerevisiae. 24 c2ochA_ not modelled 98.2 28 PDB header:chaperone Chain: A: PDB Molecule:hypothetical protein dnj-12; PDBTitle: j-domain of dnj-12 from caenorhabditis elegans 25 c2guzO_ not modelled 98.1 16 PDB header:chaperone, protein transport Chain: O: PDB Molecule:mitochondrial import inner membrane translocase PDBTitle: structure of the tim14-tim16 complex of the mitochondrial2 protein import motor 26 c2dn9A_ not modelled 98.1 30 PDB header:apoptosis, chaperone Chain: A: PDB Molecule:dnaj homolog subfamily a member 3; PDBTitle: solution structure of j-domain from the dnaj homolog, human2 tid1 protein 27 c2cugA_ not modelled 98.1 26 PDB header:chaperone Chain: A: PDB Molecule:mkiaa0962 protein; PDBTitle: solution structure of the j domain of the pseudo dnaj2 protein, mouse hypothetical mkiaa0962 28 c3ag7A_ not modelled 98.0 23 PDB header:plant protein Chain: A: PDB Molecule:putative uncharacterized protein f9e10.5; PDBTitle: an auxilin-like j-domain containing protein, jac1 j-domain 29 c1bq0A_ not modelled 97.8 30 PDB header:chaperone Chain: A: PDB Molecule:dnaj; PDBTitle: j-domain (residues 1-77) of the escherichia coli n-terminal2 fragment (residues 1-104) of the molecular chaperone dnaj,3 nmr, 20 structures 30 d1fpoa1 not modelled 97.8 11 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 31 d1nz6a_ not modelled 97.7 16 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 32 c2guzD_ not modelled 97.7 20 PDB header:chaperone, protein transport Chain: D: PDB Molecule:mitochondrial import inner membrane translocase PDBTitle: structure of the tim14-tim16 complex of the mitochondrial2 protein import motor 33 d1n4ca_ not modelled 95.7 13 Fold:Long alpha-hairpin Superfamily:Chaperone J-domain Family:Chaperone J-domain 34 c3uo2A_ not modelled 90.1 20 PDB header:chaperone Chain: A: PDB Molecule:j-type co-chaperone jac1, mitochondrial; PDBTitle: jac1 co-chaperone from saccharomyces cerevisiae 35 c2y4tA_ not modelled 90.1 20 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) 36 c3beeB_ 87.0 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative yfre protein; PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus 37 c3apoA_ not modelled 83.0 37 PDB header:oxidoreductase Chain: A: PDB Molecule:dnaj homolog subfamily c member 10; PDBTitle: crystal structure of full-length erdj5 38 c3urzB_ 75.4 17 PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution 39 c2katA_ not modelled 67.0 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206 40 c2e2eA_ 57.3 16 PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 41 c2r5sB_ 57.0 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp0806; PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633 42 c1na3A_ not modelled 51.3 19 PDB header:de novo protein Chain: A: PDB Molecule:designed protein ctpr2; PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif 43 c2ho1B_ not modelled 50.7 3 PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf 44 c3gyzB_ not modelled 48.9 4 PDB header:chaperone Chain: B: PDB Molecule:chaperone protein ipgc; PDBTitle: crystal structure of ipgc from shigella flexneri 45 c2vsnB_ not modelled 48.9 20 PDB header:transferase Chain: B: PDB Molecule:xcogt; PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation 46 c3m1gC_ not modelled 48.8 22 PDB header:transferase Chain: C: PDB Molecule:putative glutathione s-transferase; PDBTitle: the structure of a putative glutathione s-transferase from2 corynebacterium glutamicum 47 d2pqrb1 not modelled 46.2 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 48 c1kt0A_ not modelled 42.2 15 PDB header:isomerase Chain: A: PDB Molecule:51 kda fk506-binding protein; PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes 49 c3qdnA_ not modelled 40.2 18 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 50 d2axta1 not modelled 38.4 14 Fold:Bacterial photosystem II reaction centre, L and M subunits Superfamily:Bacterial photosystem II reaction centre, L and M subunits Family:Bacterial photosystem II reaction centre, L and M subunits 51 c3q49B_ not modelled 37.6 13 PDB header:ligase/chaperone Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1; PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide 52 d1wtya_ not modelled 37.4 20 Fold:Four-helical up-and-down bundle Superfamily:Nucleotidyltransferase substrate binding subunit/domain Family:Family 1 bi-partite nucleotidyltransferase subunit 53 d1wh7a_ not modelled 35.6 32 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Homeodomain 54 c3lyiA_ not modelled 35.6 28 PDB header:transcription Chain: A: PDB Molecule:bromodomain-containing protein 1; PDBTitle: pwwp domain of human bromodomain-containing protein 1 55 d1nzna_ not modelled 35.3 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 56 c3k9iA_ not modelled 31.6 13 PDB header:protein binding Chain: A: PDB Molecule:bh0479 protein; PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution 57 c2xcbA_ not modelled 30.9 10 PDB header:protein binding Chain: A: PDB Molecule:regulatory protein pcrh; PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd 58 d1l9bm_ not modelled 30.4 21 Fold:Bacterial photosystem II reaction centre, L and M subunits Superfamily:Bacterial photosystem II reaction centre, L and M subunits Family:Bacterial photosystem II reaction centre, L and M subunits 59 c2kcvA_ not modelled 30.1 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tetratricopeptide repeat domain protein; PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c 60 c2wukD_ not modelled 28.8 35 PDB header:cell cycle Chain: D: PDB Molecule:septum site-determining protein diviva; PDBTitle: diviva n-terminal domain, f17a mutant 61 d1h2vc2 not modelled 28.6 20 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:MIF4G domain-like 62 d1y8ma1 not modelled 28.5 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 63 c3pfsA_ not modelled 28.1 25 PDB header:protein binding Chain: A: PDB Molecule:bromodomain and phd finger-containing protein 3; PDBTitle: pwwp domain of human bromodomain and phd finger-containing protein 3 64 c3pe3D_ not modelled 25.9 13 PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate 65 c2x35A_ not modelled 24.8 38 PDB header:transcription Chain: A: PDB Molecule:peregrin; PDBTitle: molecular basis of histone h3k36me3 recognition by the pwwp2 domain of brpf1. 66 d2ooea1 not modelled 24.4 8 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 67 d2i5nl1 not modelled 23.1 14 Fold:Bacterial photosystem II reaction centre, L and M subunits Superfamily:Bacterial photosystem II reaction centre, L and M subunits Family:Bacterial photosystem II reaction centre, L and M subunits 68 d1i4aa_ not modelled 21.3 16 Fold:Annexin Superfamily:Annexin Family:Annexin 69 c3ly8A_ not modelled 21.2 10 PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc 70 c3myxA_ not modelled 20.9 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pspto_0244; PDBTitle: crystal structure of a pspto_0244 (protein with unknown function which2 belongs to pfam duf861 family) from pseudomonas syringae pv. tomato3 str. dc3000 at 1.30 a resolution 71 c3rkvA_ not modelled 20.3 12 PDB header:isomerase Chain: A: PDB Molecule:putative peptidylprolyl isomerase; PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans 72 d1ffvc1 not modelled 19.6 29 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 73 c1wao4_ not modelled 19.6 13 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 74 d2g7oa1 not modelled 19.2 25 Fold:TraM-like Superfamily:TraM-like Family:TraM-like 75 c3o3nA_ not modelled 18.6 18 PDB header:lyase Chain: A: PDB Molecule:alpha-subunit 2-hydroxyisocaproyl-coa dehydratase; PDBTitle: (r)-2-hydroxyisocaproyl-coa dehydratase in complex with its substrate2 (r)-2-hydroxyisocaproyl-coa 76 d2v7fa1 not modelled 18.3 34 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Rps19E-like 77 c2ph5A_ not modelled 18.2 28 PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 78 d1dxxa2 not modelled 18.1 25 Fold:CH domain-like Superfamily:Calponin-homology domain, CH-domain Family:Calponin-homology domain, CH-domain 79 c3hymB_ not modelled 17.4 7 PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure 80 d1omwa2 not modelled 16.7 32 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 81 c1slyA_ not modelled 15.6 16 PDB header:glycosyltransferase Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase; PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a 82 d2i5nm1 not modelled 14.8 5 Fold:Bacterial photosystem II reaction centre, L and M subunits Superfamily:Bacterial photosystem II reaction centre, L and M subunits Family:Bacterial photosystem II reaction centre, L and M subunits 83 c3mv3B_ not modelled 14.7 6 PDB header:protein transport Chain: B: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of a-cop in complex with e-cop 84 c2i3fA_ not modelled 13.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:glycolipid transfer-like protein; PDBTitle: crystal structure of a glycolipid transfer-like protein2 from galdieria sulphuraria 85 c2vq2A_ not modelled 13.7 12 PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor 86 d2pyta1 not modelled 13.6 20 Fold:Double-stranded beta-helix Superfamily:RmlC-like cupins Family:EutQ-like 87 c2jqqA_ not modelled 13.2 21 PDB header:protein transport Chain: A: PDB Molecule:conserved oligomeric golgi complex subunit 2; PDBTitle: solution structure of saccharomyces cerevisiae conserved2 oligomeric golgi subunit 2 protein (cog2p) 88 c2yicC_ not modelled 13.1 14 PDB header:lyase Chain: C: PDB Molecule:2-oxoglutarate decarboxylase; PDBTitle: crystal structure of the suca domain of mycobacterium smegmatis2 alpha-ketoglutarate decarboxylase (triclinic form) 89 d1vk9a_ not modelled 12.9 31 Fold:Cytidine deaminase-like Superfamily:Cytidine deaminase-like Family:Hypothetical protein TM1506 90 d1pc2a_ not modelled 12.8 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 91 d1o1ya_ not modelled 12.6 17 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 92 c1aoaA_ not modelled 12.5 31 PDB header:actin-binding protein Chain: A: PDB Molecule:t-fimbrin; PDBTitle: n-terminal actin-crosslinking domain from human fimbrin 93 c2if4A_ not modelled 12.5 16 PDB header:signaling protein Chain: A: PDB Molecule:atfkbp42; PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana 94 c3abqA_ not modelled 12.4 16 PDB header:lyase Chain: A: PDB Molecule:ethanolamine ammonia-lyase heavy chain; PDBTitle: crystal structure of ethanolamine ammonia-lyase from escherichia coli2 complexed with cn-cbl and 2-amino-1-propanol 95 d1hxia_ not modelled 12.3 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 96 c3o7kA_ not modelled 12.3 21 PDB header:lyase Chain: A: PDB Molecule:ohcu decarboxylase; PDBTitle: crystal structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline2 decarboxylase from klebsiella pneumoniae 97 d2buga1 not modelled 12.2 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 98 d1eysl_ not modelled 11.8 24 Fold:Bacterial photosystem II reaction centre, L and M subunits Superfamily:Bacterial photosystem II reaction centre, L and M subunits Family:Bacterial photosystem II reaction centre, L and M subunits 99 d1n62c1 not modelled 11.6 23 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0