Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	T	I	A	S	V	T	L	P	H	H	V	H	A	P	R	Y	D	R	Q	Q	L	Q	S	R	I	V	H	F	G	F	G	A	F	H	R	A	H	Q	A	L	L	T	D	R	V	L	N	A	Q	G	G	D	W	G	I	C	E	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	L	F	S	G	D	Q	L	M	S	Q	L	R	A	Q	N	H	L	Y	T	V	L	E	K	G	A	D	G	N	Q	V	I	I	V	G	A	V	H	E	C	L	N	A	K	L	D	S	L	A	A	I	I	E	K	F	C	E	P	Q	V
Secondary structure
SS confidence
Disorder					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	I	V	S	L	T	I	T	E	K	G	Y	C	I	D	P	A	T	G	A	L	D	T	S	N	P	R	I	I	H	D	L	Q	T	P	E	E	P	H	S	A	P	G	I	L	V	E	A	L	K	R	R	R	E	R	G	L	T	P	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	V	L	S	C	D	N	I	P	D	N	G	H	V	V	K	N	A	V	L	G	M	A	E	K	R	S	P	E	L	A	G	W	I	K	E	H	V	S	F	P	G	T	M	V	D	R	I	V	P	A	A	T	D	E	S	L	V	E	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	Q	H	L	G	V	N	D	P	C	A	I	S	C	E	P	F	I	Q	W	V	V	E	D	N	F	V	A	G	R	P	A	W	E	V	A	G	V	Q	M	V	N	D	V	L	P	W	E	E	M	K	L	R	M	L	N	G	S	H	S
Secondary structure
SS confidence
Disorder																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	L	A	Y	L	G	Y	L	S	G	F	A	H	I	S	D	C	M	Q	D	R	A	F	R	H	A	A	R	T	L	M	L	D	E	Q	A	P	T	L	Q	I	K	D	V	D	L	T	Q	Y	A	D	K	L	I	A	R	F	A	N	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	L	K	H	K	T	W	Q	I	A	M	D	G	S	Q	K	L	P	Q	R	M	L	A	G	I	R	I	H	Q	G	R	E	T	D	W	S	L	L	A	L	G	V	A	G	W	M	R	Y	V	S	G	V	D	D	A	G	N	A	I	D
Secondary structure
SS confidence
Disorder										?		?	?					?	?																																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		V	R	D	P	L	S	D	K	I	R	E	L	V	A	G	S	S	S	E	Q	R	V	T	A	L	L	S	L	R	E	V	F	G	D	D	L	P	D	N	P	H	F	V	Q	A	I	E	Q	A	W	Q	Q	I	V	Q	F	G	A	H	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		A	L	L	N	T	L	K	I
Secondary structure
SS confidence
Disorder								?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1m2w chain A Region: 1 - 487 Aligned: 484 Modelled: 487 Confidence: 100.0% Identity: 39% PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol dehydrogenase; PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol Phyre2 PDB 3h2z chain A Region: 26 - 474 Aligned: 369 Modelled: 408 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri Phyre2 PDB 1lj8 chain A domain 4 Region: 1 - 282 Aligned: 281 Modelled: 282 Confidence: 100.0% Identity: 43% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: 6-phosphogluconate dehydrogenase-like, N-terminal domain Phyre2 PDB 1lj8 chain A domain 3 Region: 283 - 487 Aligned: 203 Modelled: 205 Confidence: 100.0% Identity: 33% Fold: 6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily: 6-phosphogluconate dehydrogenase C-terminal domain-like Family: Mannitol 2-dehydrogenase Phyre2 PDB 2axq chain A Region: 26 - 127 Aligned: 72 Modelled: 74 Confidence: 69.0% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae Phyre2 PDB 3mtj chain A Region: 24 - 126 Aligned: 98 Modelled: 103 Confidence: 42.8% Identity: 13% PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a Phyre2 PDB 1gzs chain B Region: 322 - 365 Aligned: 44 Modelled: 44 Confidence: 41.2% Identity: 18% Fold: SopE-like GEF domain Superfamily: SopE-like GEF domain Family: SopE-like GEF domain Phyre2 PDB 3mio chain A Region: 173 - 217 Aligned: 44 Modelled: 45 Confidence: 38.3% Identity: 25% PDB header:lyase Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase; PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00 Phyre2 PDB 1k4i chain A Region: 167 - 217 Aligned: 50 Modelled: 51 Confidence: 34.6% Identity: 12% Fold: YrdC/RibB Superfamily: YrdC/RibB Family: 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB Phyre2 PDB 3fgg chain A Region: 304 - 357 Aligned: 54 Modelled: 54 Confidence: 31.8% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bce2196; PDBTitle: crystal structure of putative ecf-type sigma factor negative effector2 from bacillus cereus Phyre2 PDB 1snn chain A Region: 167 - 213 Aligned: 46 Modelled: 47 Confidence: 28.2% Identity: 28% Fold: YrdC/RibB Superfamily: YrdC/RibB Family: 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB Phyre2 PDB 3nt5 chain B Region: 23 - 78 Aligned: 50 Modelled: 56 Confidence: 27.0% Identity: 22% PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose Phyre2 PDB 1qus chain A Region: 319 - 471 Aligned: 118 Modelled: 136 Confidence: 24.7% Identity: 8% Fold: Lysozyme-like Superfamily: Lysozyme-like Family: Bacterial muramidase, catalytic domain Phyre2 PDB 2ph5 chain A Region: 23 - 61 Aligned: 35 Modelled: 39 Confidence: 22.8% Identity: 26% PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 Phyre2 PDB 3h8g chain C Region: 130 - 191 Aligned: 60 Modelled: 62 Confidence: 20.9% Identity: 13% PDB header:hydrolase Chain: C: PDB Molecule:cytosol aminopeptidase; PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida Phyre2 PDB 3euw chain B Region: 23 - 77 Aligned: 48 Modelled: 55 Confidence: 20.3% Identity: 27% PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 Phyre2 PDB 1yy3 chain A Region: 28 - 116 Aligned: 87 Modelled: 89 Confidence: 18.9% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:s-adenosylmethionine:trna ribosyltransferase- PDBTitle: structure of s-adenosylmethionine:trna ribosyltransferase-2 isomerase (quea) Phyre2 PDB 2o8r chain A domain 3 Region: 26 - 36 Aligned: 11 Modelled: 11 Confidence: 18.5% Identity: 27% Fold: Phospholipase D/nuclease Superfamily: Phospholipase D/nuclease Family: Polyphosphate kinase C-terminal domain Phyre2 PDB 3cwc chain B Region: 111 - 184 Aligned: 46 Modelled: 47 Confidence: 17.9% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 Phyre2 PDB 1r0k chain A domain 2 Region: 24 - 128 Aligned: 98 Modelled: 105 Confidence: 16.3% Identity: 7% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 1 c1m2wA_ 2 c3h2zA_ 3 d1lj8a4 4 d1lj8a3 5 c2axqA_ 6 c3mtjA_ 7 d1gzsb_ 8 c3mioA_ 9 d1k4ia_ 10 c3fggA_ 11 d1snna_ 12 c3nt5B_ 13 d1qusa_ 14 c2ph5A_ 15 c3h8gC_ 16 c3euwB_ 17 c1yy3A_ 18 d2o8ra3 19 c3cwcB_ 20 d1r0ka2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1m2wA_ 100.0 39 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol dehydrogenase; PDBTitle: pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with2 nad and d-mannitol 2 c3h2zA_ 100.0 25 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri 3 d1lj8a4 100.0 43 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 4 d1lj8a3 100.0 33 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:Mannitol 2-dehydrogenase 5 c2axqA_ 69.0 15 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae 6 c3mtjA_ 42.8 13 PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a 7 d1gzsb_ 41.2 18 Fold:SopE-like GEF domain Superfamily:SopE-like GEF domain Family:SopE-like GEF domain 8 c3mioA_ 38.3 25 PDB header:lyase Chain: A: PDB Molecule:3,4-dihydroxy-2-butanone 4-phosphate synthase; PDBTitle: crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase2 domain from mycobacterium tuberculosis at ph 6.00 9 d1k4ia_ 34.6 12 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 10 c3fggA_ 31.8 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein bce2196; PDBTitle: crystal structure of putative ecf-type sigma factor negative effector2 from bacillus cereus 11 d1snna_ 28.2 28 Fold:YrdC/RibB Superfamily:YrdC/RibB Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB 12 c3nt5B_ 27.0 22 PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose 13 d1qusa_ 24.7 8 Fold:Lysozyme-like Superfamily:Lysozyme-like Family:Bacterial muramidase, catalytic domain 14 c2ph5A_ 22.8 26 PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 15 c3h8gC_ 20.9 13 PDB header:hydrolase Chain: C: PDB Molecule:cytosol aminopeptidase; PDBTitle: bestatin complex structure of leucine aminopeptidase from pseudomonas2 putida 16 c3euwB_ 20.3 27 PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 17 c1yy3A_ 18.9 15 PDB header:isomerase Chain: A: PDB Molecule:s-adenosylmethionine:trna ribosyltransferase- PDBTitle: structure of s-adenosylmethionine:trna ribosyltransferase-2 isomerase (quea) 18 d2o8ra3 18.5 27 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 19 c3cwcB_ 17.9 17 PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 20 d1r0ka2 16.3 7 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 21 c2o8rA_ not modelled 15.7 27 PDB header:transferase Chain: A: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of polyphosphate kinase from2 porphyromonas gingivalis 22 c1ceuA_ not modelled 15.5 44 PDB header:viral protein Chain: A: PDB Molecule:protein (hiv-1 regulatory protein n-terminal PDBTitle: nmr structure of the (1-51) n-terminal domain of the hiv-12 regulatory protein 23 c3ceaA_ not modelled 15.2 11 PDB header:oxidoreductase Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase; PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution 24 c1lanA_ not modelled 15.1 12 PDB header:hydrolase (alpha-aminoacylpeptide) Chain: A: PDB Molecule:leucine aminopeptidase; PDBTitle: leucine aminopeptidase complex with l-leucinal 25 d1gyta2 not modelled 15.1 13 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:Leucine aminopeptidase, C-terminal domain 26 c3c7cB_ not modelled 14.8 15 PDB header:oxidoreductase Chain: B: PDB Molecule:octopine dehydrogenase; PDBTitle: a structural basis for substrate and stereo selectivity in2 octopine dehydrogenase (odh-nadh-l-arginine) 27 c3b20R_ not modelled 13.6 19 PDB header:oxidoreductase Chain: R: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase (nadp+); PDBTitle: crystal structure analysis of dehydrogenase complexed with nad 28 c3guzB_ not modelled 13.2 31 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's 29 c1gytG_ not modelled 13.1 14 PDB header:hydrolase Chain: G: PDB Molecule:cytosol aminopeptidase; PDBTitle: e. coli aminopeptidase a (pepa) 30 c3egoB_ not modelled 12.3 9 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 2-dehydropantoate 2-reductase; PDBTitle: crystal structure of probable 2-dehydropantoate 2-reductase2 pane from bacillus subtilis 31 d2v0fa1 not modelled 11.7 36 Fold:GYF/BRK domain-like Superfamily:BRK domain-like Family:BRK domain-like 32 c1z9bA_ not modelled 11.5 13 PDB header:translation Chain: A: PDB Molecule:translation initiation factor if-2; PDBTitle: solution structure of the c1-subdomain of bacillus2 stearothermophilus translation initiation factor if2 33 d1e5qa1 not modelled 11.5 22 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 34 c2d2iO_ not modelled 11.2 19 PDB header:oxidoreductase Chain: O: PDB Molecule:glyceraldehyde 3-phosphate dehydrogenase; PDBTitle: crystal structure of nadp-dependent glyceraldehyde-3-2 phosphate dehydrogenase from synechococcus sp. complexed3 with nadp+ 35 c3kzwD_ not modelled 11.1 14 PDB header:hydrolase Chain: D: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from staphylococcus aureus2 col 36 c1e5lA_ not modelled 10.5 17 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine reductase; PDBTitle: apo saccharopine reductase from magnaporthe grisea 37 c3bjrA_ not modelled 10.5 8 PDB header:hydrolase Chain: A: PDB Molecule:putative carboxylesterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_1002) from2 lactobacillus plantarum wcfs1 at 2.09 a resolution 38 c1x5bA_ not modelled 10.3 16 PDB header:protein binding Chain: A: PDB Molecule:signal transducing adaptor molecule 2; PDBTitle: the solution structure of the vhs domain of human signal2 transducing adaptor molecule 2 39 c3tbiA_ not modelled 10.2 14 PDB header:transcription Chain: A: PDB Molecule:rna polymerase-associated protein gp33; PDBTitle: crystal structure of t4 gp33 bound to e. coli rnap beta-flap domain 40 d1o7fa1 not modelled 10.0 29 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:DEP domain 41 c2qytA_ not modelled 9.6 19 PDB header:oxidoreductase Chain: A: PDB Molecule:2-dehydropantoate 2-reductase; PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from porphyromonas2 gingivalis w83 42 c1h6dL_ not modelled 9.2 13 PDB header:protein translocation Chain: L: PDB Molecule:precursor form of glucose-fructose PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol 43 c1ofgF_ not modelled 9.2 13 PDB header:oxidoreductase Chain: F: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: glucose-fructose oxidoreductase 44 c2c9lZ_ not modelled 9.0 40 PDB header:viral protein Chain: Z: PDB Molecule:bzlf1 trans-activator protein; PDBTitle: structure of the epstein-barr virus zebra protein 45 d1r6ea_ not modelled 8.6 21 Fold:SopE-like GEF domain Superfamily:SopE-like GEF domain Family:SopE-like GEF domain 46 c2hc9A_ not modelled 8.5 15 PDB header:hydrolase Chain: A: PDB Molecule:leucine aminopeptidase 1; PDBTitle: structure of caenorhabditis elegans leucine aminopeptidase-zinc2 complex (lap1) 47 d1to6a_ not modelled 8.2 20 Fold:Glycerate kinase I Superfamily:Glycerate kinase I Family:Glycerate kinase I 48 c2cu2A_ not modelled 8.2 22 PDB header:transferase Chain: A: PDB Molecule:putative mannose-1-phosphate guanylyl transferase; PDBTitle: crystal structure of mannose-1-phosphate geranyltransferase from2 thermus thermophilus hb8 49 d1dvpa1 not modelled 8.2 14 Fold:alpha-alpha superhelix Superfamily:ENTH/VHS domain Family:VHS domain 50 c3ingA_ not modelled 8.2 13 PDB header:oxidoreductase Chain: A: PDB Molecule:homoserine dehydrogenase; PDBTitle: crystal structure of homoserine dehydrogenase (np_394635.1) from2 thermoplasma acidophilum at 1.95 a resolution 51 c3omdB_ not modelled 8.2 8 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of unknown function protein from leptospirillum2 rubarum 52 c1dvpA_ not modelled 8.1 14 PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine PDBTitle: crystal structure of the vhs and fyve tandem domains of hrs,2 a protein involved in membrane trafficking and signal3 transduction 53 c3q2kB_ not modelled 8.1 17 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca 54 d2py6a1 not modelled 8.0 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:FkbM-like 55 c3zyqA_ not modelled 7.7 12 PDB header:signaling Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution 56 c3dapB_ not modelled 7.6 17 PDB header:oxidoreductase Chain: B: PDB Molecule:diaminopimelic acid dehydrogenase; PDBTitle: c. glutamicum dap dehydrogenase in complex with nadp+ and2 the inhibitor 5s-isoxazoline 57 d1q0qa2 not modelled 7.1 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 58 c3euhB_ not modelled 6.9 15 PDB header:cell cycle Chain: B: PDB Molecule:chromosome partition protein mukf; PDBTitle: crystal structure of the muke-mukf complex 59 d1u2ka_ not modelled 6.8 29 Fold:Heme-dependent peroxidases Superfamily:Heme-dependent peroxidases Family:Catalase-peroxidase KatG 60 d1xdpa3 not modelled 6.8 50 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 61 c3rrlC_ not modelled 6.6 24 PDB header:transferase Chain: C: PDB Molecule:succinyl-coa:3-ketoacid-coenzyme a transferase subunit a; PDBTitle: complex structure of 3-oxoadipate coa-transferase subunit a and b from2 helicobacter pylori 26695 62 d1f06a1 not modelled 6.6 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 63 c2rkhA_ not modelled 6.5 44 PDB header:transcription Chain: A: PDB Molecule:putative apha-like transcription factor; PDBTitle: crystal structure of a putative apha-like transcription factor2 (zp_00208345.1) from magnetospirillum magnetotacticum ms-1 at 2.00 a3 resolution 64 d2cu2a2 not modelled 6.5 15 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:mannose-1-phosphate guanylyl transferase 65 d1hcia1 not modelled 6.5 23 Fold:Spectrin repeat-like Superfamily:Spectrin repeat Family:Spectrin repeat 66 c2k2iB_ not modelled 6.3 50 PDB header:cell cycle Chain: B: PDB Molecule:sfi1 peptide; PDBTitle: nmr solution structure of the c-terminal domain (t94-y172)2 of the human centrin 2 in complex with a repeat sequence of3 human sfi1 (r641-t660) 67 d1uj8a1 not modelled 6.2 16 Fold:Another 3-helical bundle Superfamily:IscX-like Family:IscX-like 68 c1fi0A_ not modelled 6.2 44 PDB header:viral protein Chain: A: PDB Molecule:vpr protein; PDBTitle: solution structure of hiv-1 vpr (13-33) peptide in micells 69 d1mv8a2 not modelled 6.1 24 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 70 c1u2jC_ not modelled 5.9 29 PDB header:oxidoreductase Chain: C: PDB Molecule:peroxidase/catalase hpi; PDBTitle: crystal structure of the c-terminal domain from the2 catalase-peroxidase katg of escherichia coli (p21 21 21) 71 c2o8sA_ not modelled 5.9 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:agr_c_984p; PDBTitle: x-ray crystal structure of protein agr_c_984 from agrobacterium2 tumefaciens. northeast structural genomics consortium target atr120. 72 c2jz1A_ not modelled 5.8 23 PDB header:transcription Chain: A: PDB Molecule:protein doublesex; PDBTitle: dsx_long 73 c3jruB_ not modelled 5.7 17 PDB header:hydrolase Chain: B: PDB Molecule:probable cytosol aminopeptidase; PDBTitle: crystal structure of leucyl aminopeptidase (pepa) from xoo0834,2 xanthomonas oryzae pv. oryzae kacc10331 74 c1iq5B_ not modelled 5.7 67 PDB header:metal binding protein/protein binding Chain: B: PDB Molecule:ca2+/calmodulin dependent kinase kinase; PDBTitle: calmodulin/nematode ca2+/calmodulin dependent kinase kinase2 fragment 75 d1txga2 not modelled 5.7 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:6-phosphogluconate dehydrogenase-like, N-terminal domain 76 d2dt5a2 not modelled 5.6 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Transcriptional repressor Rex, C-terminal domain 77 c3kr5E_ not modelled 5.6 17 PDB header:hydrolase Chain: E: PDB Molecule:m17 leucyl aminopeptidase; PDBTitle: structure of a protease 4 78 c3ketA_ not modelled 5.5 23 PDB header:transcription/dna Chain: A: PDB Molecule:redox-sensing transcriptional repressor rex; PDBTitle: crystal structure of a rex-family transcriptional regulatory protein2 from streptococcus agalactiae bound to a palindromic operator 79 c1s6cB_ not modelled 5.5 38 PDB header:transport protein Chain: B: PDB Molecule:potassium voltage-gated channel subfamily d member 2; PDBTitle: crystal structure of the complex between kchip1 and kv4.2 n1-30 80 c3ij3A_ not modelled 5.5 17 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: 1.8 angstrom resolution crystal structure of cytosol aminopeptidase2 from coxiella burnetii 81 c3ktwA_ not modelled 5.4 26 PDB header:rna/rna binding protein Chain: A: PDB Molecule:signal recognition particle 19 kda protein; PDBTitle: crystal structure of the srp19/s-domain srp rna complex of sulfolobus2 solfataricus 82 c3ghyA_ not modelled 5.2 12 PDB header:oxidoreductase Chain: A: PDB Molecule:ketopantoate reductase protein; PDBTitle: crystal structure of a putative ketopantoate reductase from ralstonia2 solanacearum molk2 83 d1k8kg_ not modelled 5.2 6 Fold:alpha-alpha superhelix Superfamily:Arp2/3 complex 16 kDa subunit ARPC5 Family:Arp2/3 complex 16 kDa subunit ARPC5 84 d2hiqa1 not modelled 5.1 20 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Hypothetical protein YdhR

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0