Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	G	W	V	I	T	C	H	D	D	R	A	Q	E	I	L	D	A	L	E	K	K	H	G	A	L	L	Q	C	R	A	V	N	F	W	R	G	L	S	S	N	M	L	S	R	M	M	C	D	A	L	H	E	A	D	S	G	E	G
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	I	F	L	T	D	I	A	G	A	P	P	Y	R	V	A	S	L	L	S	H	K	H	S	R	C	E	V	I	S	G	V	T	L	P	L	I	E	Q	M	M	A	C	R	E	T	M	T	S	S	E	F	R	E	R	I	V	E	L	G
Secondary structure
SS confidence
Disorder																																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.
Sequence		A	P	E	V	S	S	L	W	H	Q	Q	Q	K	N	P	P	F	V	L	K	H	N	L	Y	E	Y
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1pdo chain A Region: 2 - 128 Aligned: 127 Modelled: 127 Confidence: 100.0% Identity: 27% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: EIIA-man component-like Phyre2 PDB 3ipr chain C Region: 1 - 131 Aligned: 131 Modelled: 131 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: C: PDB Molecule:pts system, iia component; PDBTitle: crystal structure of the enterococcus faecalis gluconate2 specific eiia phosphotransferase system component Phyre2 PDB 3lfh chain F Region: 2 - 129 Aligned: 127 Modelled: 128 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: F: PDB Molecule:phosphotransferase system, mannose/fructose-specific PDBTitle: crystal structure of manxa from thermoanaerobacter tengcongensis Phyre2 PDB 3mtq chain A Region: 2 - 133 Aligned: 130 Modelled: 132 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:putative phosphoenolpyruvate-dependent sugar PDBTitle: crystal structure of a putative phosphoenolpyruvate-dependent sugar2 phosphotransferase system (pts) permease (kpn_04802) from klebsiella3 pneumoniae subsp. pneumoniae mgh 78578 at 1.70 a resolution Phyre2 PDB 3bed chain A domain 1 Region: 3 - 127 Aligned: 122 Modelled: 0 Confidence: 100.0% Identity: 18% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: EIIA-man component-like Phyre2 PDB 3gx1 chain A Region: 2 - 122 Aligned: 119 Modelled: 121 Confidence: 99.9% Identity: 9% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin1832 protein; PDBTitle: crystal structure of a domain of lin1832 from listeria innocua Phyre2 PDB 3b48 chain A domain 1 Region: 2 - 123 Aligned: 121 Modelled: 122 Confidence: 99.8% Identity: 12% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: DhaM-like Phyre2 PDB 3gdw chain A Region: 2 - 128 Aligned: 124 Modelled: 127 Confidence: 99.5% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sigma-54 interaction domain protein; PDBTitle: crystal structure of sigma-54 interaction domain protein from2 enterococcus faecalis Phyre2 PDB 3ct6 chain A domain 1 Region: 1 - 119 Aligned: 116 Modelled: 119 Confidence: 99.1% Identity: 11% Fold: PTS system fructose IIA component-like Superfamily: PTS system fructose IIA component-like Family: DhaM-like Phyre2 PDB 2btq chain B Region: 8 - 90 Aligned: 66 Modelled: 66 Confidence: 90.9% Identity: 15% PDB header:structural protein Chain: B: PDB Molecule:tubulin btubb; PDBTitle: structure of btubab heterodimer from prosthecobacter2 dejongeii Phyre2 PDB 3edl chain A Region: 42 - 81 Aligned: 40 Modelled: 40 Confidence: 88.7% Identity: 13% PDB header:structural protein Chain: A: PDB Molecule:alpha-tubulin; PDBTitle: kinesin13-microtubule ring complex Phyre2 PDB 2p4n chain B Region: 42 - 90 Aligned: 49 Modelled: 49 Confidence: 87.8% Identity: 12% PDB header:transport protein Chain: B: PDB Molecule:tubulin beta chain; PDBTitle: human monomeric kinesin (1bg2) and bovine tubulin (1jff)2 docked into the 9-angstrom cryo-em map of nucleotide-free3 kinesin complexed to the microtubule Phyre2 PDB 2bto chain A Region: 42 - 90 Aligned: 49 Modelled: 49 Confidence: 87.0% Identity: 24% PDB header:cytoskeletal protein Chain: A: PDB Molecule:tubulin btuba; PDBTitle: structure of btuba from prosthecobacter dejongeii Phyre2 PDB 2bto chain A domain 1 Region: 41 - 90 Aligned: 50 Modelled: 50 Confidence: 85.2% Identity: 24% Fold: Tubulin nucleotide-binding domain-like Superfamily: Tubulin nucleotide-binding domain-like Family: Tubulin, GTPase domain Phyre2 PDB 1z5w chain A Region: 42 - 90 Aligned: 49 Modelled: 49 Confidence: 84.5% Identity: 20% PDB header:structural protein Chain: A: PDB Molecule:tubulin gamma-1 chain; PDBTitle: crystal structure of gamma-tubulin bound to gtp Phyre2 PDB 1tub chain A domain 1 Region: 42 - 95 Aligned: 54 Modelled: 54 Confidence: 83.3% Identity: 11% Fold: Tubulin nucleotide-binding domain-like Superfamily: Tubulin nucleotide-binding domain-like Family: Tubulin, GTPase domain Phyre2 PDB 1tub chain B domain 1 Region: 42 - 95 Aligned: 54 Modelled: 54 Confidence: 72.4% Identity: 13% Fold: Tubulin nucleotide-binding domain-like Superfamily: Tubulin nucleotide-binding domain-like Family: Tubulin, GTPase domain Phyre2 PDB 3lcm chain B Region: 1 - 72 Aligned: 72 Modelled: 72 Confidence: 68.9% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159 Phyre2 PDB 3lup chain A Region: 40 - 122 Aligned: 82 Modelled: 83 Confidence: 66.5% Identity: 15% PDB header:structure genomics, unknown function Chain: A: PDB Molecule:degv family protein; PDBTitle: crystal structure of fatty acid binding degv family protein sag13422 from streptococcus agalactiae Phyre2 PDB 2vxy chain A Region: 1 - 95 Aligned: 95 Modelled: 95 Confidence: 59.2% Identity: 12% PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: the structure of ftsz from bacillus subtilis at 1.7a2 resolution Phyre2 1 d1pdoa_ 2 c3iprC_ 3 c3lfhF_ 4 c3mtqA_ 5 d3beda1 6 c3gx1A_ 7 d3b48a1 8 c3gdwA_ 9 d3ct6a1 10 c2btqB_ 11 c3edlA_ 12 c2p4nB_ 13 c2btoA_ 14 d2btoa1 15 c1z5wA_ 16 d1tuba1 17 d1tubb1 18 c3lcmB_ 19 c3lupA_ 20 c2vxyA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1pdoa_ 100.0 27 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:EIIA-man component-like 2 c3iprC_ 100.0 26 PDB header:transferase Chain: C: PDB Molecule:pts system, iia component; PDBTitle: crystal structure of the enterococcus faecalis gluconate2 specific eiia phosphotransferase system component 3 c3lfhF_ 100.0 17 PDB header:transferase Chain: F: PDB Molecule:phosphotransferase system, mannose/fructose-specific PDBTitle: crystal structure of manxa from thermoanaerobacter tengcongensis 4 c3mtqA_ 100.0 12 PDB header:transferase Chain: A: PDB Molecule:putative phosphoenolpyruvate-dependent sugar PDBTitle: crystal structure of a putative phosphoenolpyruvate-dependent sugar2 phosphotransferase system (pts) permease (kpn_04802) from klebsiella3 pneumoniae subsp. pneumoniae mgh 78578 at 1.70 a resolution 5 d3beda1 100.0 18 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:EIIA-man component-like 6 c3gx1A_ 99.9 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin1832 protein; PDBTitle: crystal structure of a domain of lin1832 from listeria innocua 7 d3b48a1 99.8 12 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:DhaM-like 8 c3gdwA_ 99.5 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sigma-54 interaction domain protein; PDBTitle: crystal structure of sigma-54 interaction domain protein from2 enterococcus faecalis 9 d3ct6a1 99.1 11 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:DhaM-like 10 c2btqB_ 90.9 15 PDB header:structural protein Chain: B: PDB Molecule:tubulin btubb; PDBTitle: structure of btubab heterodimer from prosthecobacter2 dejongeii 11 c3edlA_ 88.7 13 PDB header:structural protein Chain: A: PDB Molecule:alpha-tubulin; PDBTitle: kinesin13-microtubule ring complex 12 c2p4nB_ 87.8 12 PDB header:transport protein Chain: B: PDB Molecule:tubulin beta chain; PDBTitle: human monomeric kinesin (1bg2) and bovine tubulin (1jff)2 docked into the 9-angstrom cryo-em map of nucleotide-free3 kinesin complexed to the microtubule 13 c2btoA_ 87.0 24 PDB header:cytoskeletal protein Chain: A: PDB Molecule:tubulin btuba; PDBTitle: structure of btuba from prosthecobacter dejongeii 14 d2btoa1 85.2 24 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 15 c1z5wA_ 84.5 20 PDB header:structural protein Chain: A: PDB Molecule:tubulin gamma-1 chain; PDBTitle: crystal structure of gamma-tubulin bound to gtp 16 d1tuba1 83.3 11 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 17 d1tubb1 72.4 13 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 18 c3lcmB_ 68.9 14 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159 19 c3lupA_ 66.5 15 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:degv family protein; PDBTitle: crystal structure of fatty acid binding degv family protein sag13422 from streptococcus agalactiae 20 c2vxyA_ 59.2 12 PDB header:cell cycle Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: the structure of ftsz from bacillus subtilis at 1.7a2 resolution 21 d1xm7a_ not modelled 51.9 9 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Hypothetical protein aq 1666 22 c3rpeA_ not modelled 45.8 11 PDB header:oxidoreductase Chain: A: PDB Molecule:modulator of drug activity b; PDBTitle: 1.1 angstrom crystal structure of putative modulator of drug activity2 (mdab) from yersinia pestis co92. 23 d1mgpa_ not modelled 41.5 17 Fold:DAK1/DegV-like Superfamily:DAK1/DegV-like Family:DegV-like 24 c1mgpA_ not modelled 41.5 17 PDB header:lipid binding protein Chain: A: PDB Molecule:hypothetical protein tm841; PDBTitle: hypothetical protein tm841 from thermotoga maritima reveals2 fatty acid binding function 25 c2g7zB_ not modelled 39.9 5 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein spy1493; PDBTitle: conserved degv-like protein of unknown function from streptococcus2 pyogenes m1 gas binds long-chain fatty acids 26 d1q0qa2 not modelled 37.0 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 27 d1t5ba_ not modelled 36.8 10 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 28 d2qwxa1 not modelled 35.0 10 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 29 c3ho6B_ not modelled 33.0 17 PDB header:toxin Chain: B: PDB Molecule:toxin a; PDBTitle: structure-function analysis of inositol hexakisphosphate-2 induced autoprocessing in clostridium difficile toxin a 30 d1a2za_ not modelled 32.8 12 Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) 31 c4a5oB_ not modelled 28.8 9 PDB header:oxidoreductase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold) 32 c3p2oA_ not modelled 27.8 9 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 33 d2amha1 not modelled 27.5 14 Fold:Anticodon-binding domain-like Superfamily:ITPase-like Family:Maf-like 34 c3l07B_ not modelled 27.2 6 PDB header:oxidoreductase,hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis. 35 d1k6ma2 not modelled 27.2 19 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain 36 c4a26B_ not modelled 27.2 14 PDB header:oxidoreductase Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic; PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase 37 c3p2oB_ not modelled 26.6 9 PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 38 d1bifa2 not modelled 23.9 19 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain 39 c1mgtA_ not modelled 22.9 11 PDB header:transferase Chain: A: PDB Molecule:protein (o6-methylguanine-dna methyltransferase); PDBTitle: crystal structure of o6-methylguanine-dna methyltransferase from2 hyperthermophilic archaeon pyrococcus kodakaraensis strain kod1 40 c3dnfB_ not modelled 22.8 17 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway 41 c3ha2B_ not modelled 22.4 8 PDB header:oxidoreductase Chain: B: PDB Molecule:nadph-quinone reductase; PDBTitle: crystal structure of protein (nadph-quinone reductase) from2 p.pentosaceus, northeast structural genomics consortium target ptr24a 42 c3lyhB_ not modelled 22.0 12 PDB header:lyase Chain: B: PDB Molecule:cobalamin (vitamin b12) biosynthesis cbix protein; PDBTitle: crystal structure of putative cobalamin (vitamin b12) biosynthesis2 cbix protein (yp_958415.1) from marinobacter aquaeolei vt8 at 1.60 a3 resolution 43 c2dt8A_ not modelled 21.7 19 PDB header:lipid binding protein Chain: A: PDB Molecule:degv family protein; PDBTitle: fatty acid binding of a degv family protein from thermus thermophilus 44 c2hqbA_ not modelled 20.6 12 PDB header:transcription Chain: A: PDB Molecule:transcriptional activator of comk gene; PDBTitle: crystal structure of a transcriptional activator of comk2 gene from bacillus halodurans 45 d1rtta_ not modelled 19.1 7 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 46 c2qniA_ not modelled 18.9 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu0299; PDBTitle: crystal structure of uncharacterized protein atu0299 47 c3eglC_ not modelled 17.5 13 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:degv family protein; PDBTitle: crystal structure of degv family protein cg2579 from corynebacterium2 glutamicum 48 d1ul3a_ not modelled 16.5 16 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 49 c2jh3C_ not modelled 16.2 18 PDB header:ribosomal protein Chain: C: PDB Molecule:ribosomal protein s2-related protein; PDBTitle: the crystal structure of dr2241 from deinococcus2 radiodurans at 1.9 a resolution reveals a multi-domain3 protein with structural similarity to chelatases but also4 with two additional novel domains 50 c1b0aA_ not modelled 15.8 9 PDB header:oxidoreductase,hydrolase Chain: A: PDB Molecule:protein (fold bifunctional protein); PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli. 51 c1pd7B_ not modelled 15.5 0 PDB header:transcription Chain: B: PDB Molecule:mad1; PDBTitle: extended sid of mad1 bound to the pah2 domain of msin3b 52 c3r7aA_ not modelled 14.8 11 PDB header:transferase Chain: A: PDB Molecule:phosphoglycerate mutase, putative; PDBTitle: crystal structure of phosphoglycerate mutase from bacillus anthracis2 str. sterne 53 c3f2vA_ not modelled 14.7 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:general stress protein 14; PDBTitle: crystal structure of the general stress protein 142 (tde0354) in complex with fmn from treponema denticola,3 northeast structural genomics consortium target tdr58. 54 c3dcyA_ not modelled 14.4 11 PDB header:apoptosis regulator Chain: A: PDB Molecule:regulator protein; PDBTitle: crystal structure a tp53-induced glycolysis and apoptosis2 regulator protein from homo sapiens. 55 c3eznB_ not modelled 14.4 18 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglyceromutase from burkholderia2 pseudomallei 1710b 56 c2gi4A_ not modelled 13.2 16 PDB header:hydrolase Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase; PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni. 57 d1jsca3 not modelled 13.2 14 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 58 c1bifA_ not modelled 13.2 19 PDB header:bifunctional enzyme Chain: A: PDB Molecule:6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase; PDBTitle: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase bifunctional2 enzyme complexed with atp-g-s and phosphate 59 d3pgma_ not modelled 12.9 18 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:Cofactor-dependent phosphoglycerate mutase 60 c2e0kA_ not modelled 12.9 14 PDB header:transferase Chain: A: PDB Molecule:precorrin-2 c20-methyltransferase; PDBTitle: crystal structure of cbil, a methyltransferase involved in anaerobic2 vitamin b12 biosynthesis 61 c3d8hB_ not modelled 12.8 18 PDB header:isomerase Chain: B: PDB Molecule:glycolytic phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglycerate mutase from cryptosporidium2 parvum, cgd7_4270 62 d1qrda_ not modelled 12.6 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Quinone reductase 63 c3k35D_ not modelled 12.5 17 PDB header:hydrolase Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: crystal structure of human sirt6 64 c3lftA_ not modelled 12.5 14 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the abc domain in complex with l-trp from2 streptococcus pneumonia to 1.35a 65 d1lssa_ not modelled 12.4 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 66 c1k6mA_ not modelled 11.9 19 PDB header:transferase, hydrolase Chain: A: PDB Molecule:6-phosphofructo-2-kinase/fructose-2,6- PDBTitle: crystal structure of human liver 6-phosphofructo-2-2 kinase/fructose-2,6-bisphosphatase 67 d2bo3a1 not modelled 11.5 29 Fold:HP0242-like Superfamily:HP0242-like Family:HP0242-like 68 c2i1vB_ not modelled 11.4 19 PDB header:transferase, hydrolase Chain: B: PDB Molecule:6-phosphofructo-2-kinase/fructose-2,6- PDBTitle: crystal structure of pfkfb3 in complex with adp and2 fructose-2,6-bisphosphate 69 c3pkiF_ not modelled 11.2 19 PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose 70 d1tipa_ not modelled 11.2 19 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, phosphatase domain 71 c2c2xB_ not modelled 11.1 10 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase- PDBTitle: three dimensional structure of bifunctional2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase3 from mycobacterium tuberculosis 72 c3gpiA_ not modelled 10.9 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus 73 c3etjB_ not modelled 10.8 13 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure e. coli purk in complex with mg, adp, and2 pi 74 d2nu7b1 not modelled 10.7 11 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 75 c3czcA_ not modelled 10.6 9 PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans 76 d1vk4a_ not modelled 10.5 22 Fold:Ribokinase-like Superfamily:Ribokinase-like Family:Ribokinase-like 77 c3m9yB_ not modelled 10.3 11 PDB header:isomerase Chain: B: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase from methicillin2 resistant staphylococcus aureus at 1.9 angstrom resolution 78 c3icrA_ not modelled 10.1 20 PDB header:oxidoreductase Chain: A: PDB Molecule:coenzyme a-disulfide reductase; PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd 79 d2hmva1 not modelled 9.9 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 80 d1h2ea_ not modelled 9.8 17 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:Cofactor-dependent phosphoglycerate mutase 81 d2b8na1 not modelled 9.5 17 Fold:GckA/TtuD-like Superfamily:GckA/TtuD-like Family:GckA/TtuD-like 82 c1a4iB_ not modelled 9.3 5 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase 83 d1nnsa_ not modelled 9.2 16 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 84 d1fzta_ not modelled 9.1 18 Fold:Phosphoglycerate mutase-like Superfamily:Phosphoglycerate mutase-like Family:Cofactor-dependent phosphoglycerate mutase 85 c3rqzC_ not modelled 9.0 22 PDB header:hydrolase Chain: C: PDB Molecule:metallophosphoesterase; PDBTitle: crystal structure of metallophosphoesterase from sphaerobacter2 thermophilus 86 c3eozB_ not modelled 9.0 17 PDB header:isomerase Chain: B: PDB Molecule:putative phosphoglycerate mutase; PDBTitle: crystal structure of phosphoglycerate mutase from plasmodium2 falciparum, pfd0660w 87 c2gamA_ not modelled 8.9 11 PDB header:transferase Chain: A: PDB Molecule:beta-1,6-n-acetylglucosaminyltransferase; PDBTitle: x-ray crystal structure of murine leukocyte-type core 2 b1,2 6-n-acetylglucosaminyltransferase (c2gnt-l) in complex3 with galb1,3galnac 88 c2ps3A_ not modelled 8.7 9 PDB header:metal transport Chain: A: PDB Molecule:high-affinity zinc uptake system protein znua; PDBTitle: structure and metal binding properties of znua, a2 periplasmic zinc transporter from escherichia coli 89 c2q1yB_ not modelled 8.6 9 PDB header:cell cycle, signaling protein Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of cell division protein ftsz from mycobacterium2 tuberculosis in complex with gtp-gamma-s 90 c3e0zB_ not modelled 8.3 6 PDB header:unknown function Chain: B: PDB Molecule:protein of unknown function; PDBTitle: crystal structure of a putative imidazole glycerol phosphate synthase2 homolog (eubrec_1070) from eubacterium rectale at 1.75 a resolution 91 d1t0ia_ not modelled 8.2 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:NADPH-dependent FMN reductase 92 c2qaiA_ not modelled 8.2 15 PDB header:hydrolase Chain: A: PDB Molecule:v-type atp synthase subunit f; PDBTitle: crystal structure of the v-type atp synthase subunit f from2 pyrococcus furiosus. nesg target pfr7. 93 d1vjta1 not modelled 8.2 8 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:LDH N-terminal domain-like 94 c1nw6A_ not modelled 8.2 12 PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin 95 d2jfga2 not modelled 8.1 9 Fold:MurD-like peptide ligases, peptide-binding domain Superfamily:MurD-like peptide ligases, peptide-binding domain Family:MurCDEF C-terminal domain 96 c3crqA_ not modelled 8.1 12 PDB header:transferase Chain: A: PDB Molecule:trna delta(2)-isopentenylpyrophosphate PDBTitle: structure of trna dimethylallyltransferase: rna2 modification through a channel 97 c3hzuA_ not modelled 8.1 6 PDB header:transferase Chain: A: PDB Molecule:thiosulfate sulfurtransferase ssea; PDBTitle: crystal structure of probable thiosulfate sulfurtransferase ssea2 (rhodanese) from mycobacterium tuberculosis 98 d1j3kc_ not modelled 8.0 24 Fold:Thymidylate synthase/dCMP hydroxymethylase Superfamily:Thymidylate synthase/dCMP hydroxymethylase Family:Thymidylate synthase/dCMP hydroxymethylase 99 c2qhpA_ not modelled 7.9 30 PDB header:transferase Chain: A: PDB Molecule:fructokinase; PDBTitle: crystal structure of fructokinase (np_810670.1) from bacteroides2 thetaiotaomicron vpi-5482 at 1.80 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0