Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP30125
DateThu Jan 5 11:45:46 GMT 2012
Unique Job ID9269bf2e45f7a43d

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1cm7a_
Top template information
Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
Confidence and coverage
Confidence:100.0% Coverage:100%
363 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPA
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Disorder  ?????






















































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   .........70.........80.........90.........100.........110.........120
Sequence  TVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF
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??????????

























???
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   .........130.........140.........150.........160.........170.........180
Sequence  CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAF
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Disorder  ??????


















?

?
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   .........190.........200.........210.........220.........230.........240
Sequence  ESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQF
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   .........250.........260.........270.........280.........290.........300
Sequence  DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA
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?
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??
















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   .........310.........320.........330.........340.........350.........360
Sequence  QILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVA
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   ...
Sequence  EGV
Secondary structure 

SS confidence 


Disorder  ???
Disorder confidence 


 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1cm7 chain A

3D model

Region: 1 - 363
Aligned: 363
Modelled: 363
Confidence: 100.0%
Identity: 100%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 1cnz chain A

3D model

Region: 1 - 363
Aligned: 363
Modelled: 363
Confidence: 100.0%
Identity: 94%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 1vlc chain A

3D model

Region: 2 - 361
Aligned: 354
Modelled: 360
Confidence: 100.0%
Identity: 57%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 3r8w chain C

3D model

Region: 3 - 360
Aligned: 356
Modelled: 358
Confidence: 100.0%
Identity: 52%
PDB header:oxidoreductase
Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic;
PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution

Phyre2

PDB 1v53 chain A domain 1

3D model

Region: 1 - 359
Aligned: 354
Modelled: 359
Confidence: 100.0%
Identity: 51%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 1a05 chain A

3D model

Region: 6 - 362
Aligned: 354
Modelled: 357
Confidence: 100.0%
Identity: 50%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 2d1c chain B

3D model

Region: 2 - 363
Aligned: 339
Modelled: 358
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: B: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8

Phyre2

PDB 3u1h chain A

3D model

Region: 6 - 363
Aligned: 348
Modelled: 357
Confidence: 100.0%
Identity: 58%
PDB header:oxidoreductase
Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase;
PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus

Phyre2

PDB 3fmx chain X

3D model

Region: 4 - 361
Aligned: 348
Modelled: 358
Confidence: 100.0%
Identity: 36%
PDB header:oxidoreductase
Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase;
PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh

Phyre2

PDB 1g2u chain A

3D model

Region: 5 - 359
Aligned: 344
Modelled: 355
Confidence: 100.0%
Identity: 51%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 1pb1 chain A

3D model

Region: 2 - 359
Aligned: 344
Modelled: 358
Confidence: 100.0%
Identity: 27%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 2d4v chain D

3D model

Region: 2 - 359
Aligned: 344
Modelled: 358
Confidence: 100.0%
Identity: 29%
PDB header:oxidoreductase
Chain: D: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans

Phyre2

PDB 1xac chain A

3D model

Region: 5 - 359
Aligned: 344
Modelled: 354
Confidence: 100.0%
Identity: 48%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 1hqs chain A

3D model

Region: 2 - 360
Aligned: 345
Modelled: 359
Confidence: 100.0%
Identity: 29%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 2e0c chain A

3D model

Region: 2 - 361
Aligned: 338
Modelled: 345
Confidence: 100.0%
Identity: 33%
PDB header:oxidoreductase
Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate
PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution

Phyre2

PDB 1wpw chain A

3D model

Region: 5 - 359
Aligned: 325
Modelled: 344
Confidence: 100.0%
Identity: 36%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 1x0l chain B

3D model

Region: 4 - 361
Aligned: 323
Modelled: 358
Confidence: 100.0%
Identity: 38%
PDB header:oxidoreductase
Chain: B: PDB Molecule:homoisocitrate dehydrogenase;
PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus

Phyre2

PDB 1w0d chain A

3D model

Region: 5 - 341
Aligned: 322
Modelled: 337
Confidence: 100.0%
Identity: 41%
Fold: Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like
Family: Dimeric isocitrate & isopropylmalate dehydrogenases

Phyre2

PDB 1tyo chain A

3D model

Region: 2 - 362
Aligned: 346
Modelled: 361
Confidence: 100.0%
Identity: 30%
PDB header:oxidoreductase
Chain: A: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp

Phyre2

PDB 3blx chain L

3D model

Region: 2 - 359
Aligned: 325
Modelled: 349
Confidence: 100.0%
Identity: 34%
PDB header:oxidoreductase
Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2;
PDBTitle: yeast isocitrate dehydrogenase (apo form)

Phyre2
1

d1cm7a_
2

d1cnza_
3

d1vlca_
4

c3r8wC_
5

d1v53a1
6

d1a05a_
7

c2d1cB_
8

c3u1hA_
9

c3fmxX_
10

d1g2ua_
11

d1pb1a_
12

c2d4vD_
13

d1xaca_
14

d1hqsa_
15

c2e0cA_
16

d1wpwa_
17

c1x0lB_
18

d1w0da_
19

c1tyoA_
20

c3blxL_
21



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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1cm7a_



100.0 100 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
2d1cnza_



100.0 94 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
3d1vlca_



100.0 57 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
4c3r8wC_



100.0 52 PDB header:oxidoreductase
Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic;
PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution
5d1v53a1



100.0 51 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
6d1a05a_



100.0 50 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
7c2d1cB_



100.0 34 PDB header:oxidoreductase
Chain: B: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8
8c3u1hA_



100.0 58 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase;
PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus
9c3fmxX_



100.0 36 PDB header:oxidoreductase
Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase;
PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh
10d1g2ua_



100.0 51 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
11d1pb1a_



100.0 27 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
12c2d4vD_



100.0 29 PDB header:oxidoreductase
Chain: D: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans
13d1xaca_



100.0 48 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
14d1hqsa_



100.0 29 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
15c2e0cA_



100.0 33 PDB header:oxidoreductase
Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate
PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution
16d1wpwa_



100.0 36 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
17c1x0lB_



100.0 38 PDB header:oxidoreductase
Chain: B: PDB Molecule:homoisocitrate dehydrogenase;
PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus
18d1w0da_



100.0 41 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
19c1tyoA_



100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp
20c3blxL_



100.0 34 PDB header:oxidoreductase
Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2;
PDBTitle: yeast isocitrate dehydrogenase (apo form)
21c1zorB_



not modelled 100.0 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: isocitrate dehydrogenase from the hyperthermophile thermotoga maritima
22c3blxM_



not modelled 100.0 31 PDB header:oxidoreductase
Chain: M: PDB Molecule:isocitrate dehydrogenase [nad] subunit 1;
PDBTitle: yeast isocitrate dehydrogenase (apo form)
23c2uxqB_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:isocitrate dehydrogenase native;
PDBTitle: isocitrate dehydrogenase from the psychrophilic bacterium2 desulfotalea psychrophila: biochemical properties and3 crystal structure analysis
24d1lwda_



not modelled 100.0 20 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
25d1t0la_



not modelled 100.0 21 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Dimeric isocitrate & isopropylmalate dehydrogenases
26c2qfyE_



not modelled 100.0 21 PDB header:oxidoreductase
Chain: E: PDB Molecule:isocitrate dehydrogenase [nadp];
PDBTitle: crystal structure of saccharomyces cerevesiae mitochondrial nadp(+)-2 dependent isocitrate dehydrogenase in complex with a-ketoglutarate
27c3us8A_



not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:isocitrate dehydrogenase [nadp];
PDBTitle: crystal structure of an isocitrate dehydrogenase from sinorhizobium2 meliloti 1021
28c2iv0A_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:isocitrate dehydrogenase;
PDBTitle: thermal stability of isocitrate dehydrogenase from2 archaeoglobus fulgidus studied by crystal structure3 analysis and engineering of chimers
29d1ptma_



not modelled 99.0 16 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:PdxA-like
30c2hi1A_



not modelled 99.0 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2;
PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium.
31d1r8ka_



not modelled 98.9 15 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:PdxA-like
32c1yxoB_



not modelled 98.3 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 1;
PDBTitle: crystal structure of pyridoxal phosphate biosynthetic protein pdxa2 pa0593
33c2b0tA_



not modelled 89.5 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp isocitrate dehydrogenase;
PDBTitle: structure of monomeric nadp isocitrate dehydrogenase
34d1itwa_



not modelled 80.9 22 Fold:Isocitrate/Isopropylmalate dehydrogenase-like
Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like
Family:Monomeric isocitrate dehydrogenase
35c3s40C_



not modelled 61.5 17 PDB header:transferase
Chain: C: PDB Molecule:diacylglycerol kinase;
PDBTitle: the crystal structure of a diacylglycerol kinases from bacillus2 anthracis str. sterne
36c1p84E_



not modelled 61.1 32 PDB header:oxidoreductase
Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur
PDBTitle: hdbt inhibited yeast cytochrome bc1 complex
37d2fpoa1



not modelled 60.6 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
38c2fyuE_



not modelled 54.7 32 PDB header:oxidoreductase
Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit,
PDBTitle: crystal structure of bovine heart mitochondrial bc1 with jg1442 inhibitor
39d1riea_



not modelled 48.9 32 Fold:ISP domain
Superfamily:ISP domain
Family:Rieske iron-sulfur protein (ISP)
40d3thia_



not modelled 44.7 16 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
41d1oria_



not modelled 42.8 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
42d2esra1



not modelled 42.3 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
43c1orhA_



not modelled 41.3 14 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 1;
PDBTitle: structure of the predominant protein arginine methyltransferase prmt1
44d3cx5e1



not modelled 40.4 32 Fold:ISP domain
Superfamily:ISP domain
Family:Rieske iron-sulfur protein (ISP)
45c2fynO_



not modelled 36.5 29 PDB header:oxidoreductase
Chain: O: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur
PDBTitle: crystal structure analysis of the double mutant rhodobacter2 sphaeroides bc1 complex
46c3cfxA_



not modelled 34.8 19 PDB header:transport protein
Chain: A: PDB Molecule:upf0100 protein ma_0280;
PDBTitle: crystal structure of m. acetivorans periplasmic binding protein2 moda/wtpa with bound tungstate
47c2nvgA_



not modelled 34.4 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit;
PDBTitle: soluble domain of rieske iron sulfur protein.
48d2onsa1



not modelled 31.8 11 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
49c2q62A_



not modelled 31.4 10 PDB header:flavoprotein
Chain: A: PDB Molecule:arsh;
PDBTitle: crystal structure of arsh from sinorhizobium meliloti
50d2fyta1



not modelled 25.2 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
51d1qapa1



not modelled 24.4 18 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
52d1jq4a_



not modelled 23.0 21 Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
53c3k6wA_



not modelled 22.7 19 PDB header:transport protein
Chain: A: PDB Molecule:solute-binding protein ma_0280;
PDBTitle: apo and ligand bound structures of moda from the archaeon2 methanosarcina acetivorans
54c3c6kC_



not modelled 22.5 10 PDB header:transferase
Chain: C: PDB Molecule:spermine synthase;
PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine
55c3cfzA_



not modelled 22.5 17 PDB header:transport protein
Chain: A: PDB Molecule:upf0100 protein mj1186;
PDBTitle: crystal structure of m. jannaschii periplasmic binding2 protein moda/wtpa with bound tungstate
56d1j08a1



not modelled 22.5 17 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
57c3ku1E_



not modelled 21.1 5 PDB header:transferase
Chain: E: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
58c2e76D_



not modelled 20.8 32 PDB header:photosynthesis
Chain: D: PDB Molecule:cytochrome b6-f complex iron-sulfur subunit;
PDBTitle: crystal structure of the cytochrome b6f complex with tridecyl-2 stigmatellin (tds) from m.laminosus
59c3l0gD_



not modelled 19.3 15 PDB header:transferase
Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution
60c2esrB_



not modelled 18.8 10 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: conserved hypothetical protein- streptococcus pyogenes
61d1f3la_



not modelled 18.0 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
62c3lwzC_



not modelled 17.9 18 PDB header:lyase
Chain: C: PDB Molecule:3-dehydroquinate dehydratase;
PDBTitle: 1.65 angstrom resolution crystal structure of type ii 3-2 dehydroquinate dehydratase (aroq) from yersinia pestis
63c2pebB_



not modelled 17.8 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative dioxygenase;
PDBTitle: crystal structure of a putative dioxygenase (npun_f1925) from nostoc2 punctiforme pcc 73102 at 1.46 a resolution
64c3p9nA_



not modelled 17.8 12 PDB header:transferase
Chain: A: PDB Molecule:possible methyltransferase (methylase);
PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase
65c3c0kB_



not modelled 17.7 15 PDB header:transferase
Chain: B: PDB Molecule:upf0064 protein yccw;
PDBTitle: crystal structure of a ribosomal rna methyltranferase
66d1g6q1_



not modelled 17.5 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
67c2huzB_



not modelled 16.8 13 PDB header:structural genomics, transferase
Chain: B: PDB Molecule:glucosamine 6-phosphate n-acetyltransferase;
PDBTitle: crystal structure of gnpnat1
68d1a8la1



not modelled 16.5 12 Fold:Thioredoxin fold
Superfamily:Thioredoxin-like
Family:PDI-like
69c2zkiH_



not modelled 15.8 19 PDB header:transcription
Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding
PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872)
70c2dumD_



not modelled 15.0 8 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:hypothetical protein ph0823;
PDBTitle: crystal structure of hypothetical protein, ph0823
71c3dloC_



not modelled 13.2 18 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:universal stress protein;
PDBTitle: structure of universal stress protein from archaeoglobus fulgidus
72d1atia1



not modelled 13.1 16 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
73d2erya1



not modelled 12.8 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:G proteins
74c1qpoA_



not modelled 12.7 13 PDB header:transferase
Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase;
PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis
75d2fhpa1



not modelled 12.7 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
76c2k4mA_



not modelled 12.6 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:upf0146 protein mth_1000;
PDBTitle: solution nmr structure of m. thermoautotrophicum protein2 mth_1000, northeast structural genomics consortium target3 tr8
77d1q77a_



not modelled 12.5 13 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:Universal stress protein-like
78c2qv7A_



not modelled 12.5 14 PDB header:transferase
Chain: A: PDB Molecule:diacylglycerol kinase dgkb;
PDBTitle: crystal structure of diacylglycerol kinase dgkb in complex with adp2 and mg
79c3cesB_



not modelled 11.3 27 PDB header:rna binding protein
Chain: B: PDB Molecule:trna uridine 5-carboxymethylaminomethyl modification enzyme
PDBTitle: crystal structure of e.coli mnmg (gida), a highly-conserved trna2 modifying enzyme
80c3hgmD_



not modelled 11.1 7 PDB header:signaling protein
Chain: D: PDB Molecule:universal stress protein tead;
PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata
81c2pfsA_



not modelled 11.0 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:universal stress protein;
PDBTitle: crystal structure of universal stress protein from nitrosomonas2 europaea
82d1cyxa_



not modelled 10.5 10 Fold:Cupredoxin-like
Superfamily:Cupredoxins
Family:Periplasmic domain of cytochrome c oxidase subunit II
83c1cyxA_



not modelled 10.5 10 PDB header:electron transport
Chain: A: PDB Molecule:cyoa;
PDBTitle: quinol oxidase (periplasmic fragment of subunit ii with2 engineered cu-a binding site)(cyoa)
84d1o4ua1



not modelled 10.5 18 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
85c3pvsA_



not modelled 10.3 25 PDB header:recombination
Chain: A: PDB Molecule:replication-associated recombination protein a;
PDBTitle: structure and biochemical activities of escherichia coli mgsa
86d1yo6a1



not modelled 10.0 39 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
87d1jmva_



not modelled 10.0 17 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:Universal stress protein-like
88d1fftb1



not modelled 9.8 10 Fold:Cupredoxin-like
Superfamily:Cupredoxins
Family:Periplasmic domain of cytochrome c oxidase subunit II
89c3fg9B_



not modelled 9.8 21 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:protein of universal stress protein uspa family;
PDBTitle: the crystal structure of an universal stress protein uspa2 family protein from lactobacillus plantarum wcfs1
90d1u8sa1



not modelled 9.8 13 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Glycine cleavage system transcriptional repressor
91c3b3jA_



not modelled 9.5 12 PDB header:transferase
Chain: A: PDB Molecule:histone-arginine methyltransferase carm1;
PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered)
92d2ffea1



not modelled 9.3 28 Fold:CofD-like
Superfamily:CofD-like
Family:CofD-like
93c2b78A_



not modelled 9.3 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein smu.776;
PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans
94c3mt0A_



not modelled 9.3 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein pa1789;
PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1
95d1xmta_



not modelled 8.7 11 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
96d1i7na1



not modelled 8.7 16 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:Synapsin domain
97d1tq8a_



not modelled 8.6 11 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:Universal stress protein-like
98d2g4ca1



not modelled 8.5 9 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
99d2r9ga1



not modelled 8.3 18 Fold:post-AAA+ oligomerization domain-like
Superfamily:post-AAA+ oligomerization domain-like
Family:MgsA/YrvN C-terminal domain-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0