Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	K	N	Y	H	I	A	V	L	P	G	D	G	I	G	P	E	V	M	T	Q	A	L	K	V	L	D	A	V	R	N	R	F	A	M	R	I	T	T	S	H	Y	D	V	G	G	A	A	I	D	N	H	G	Q	P	L	P	P	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	V	E	G	C	E	Q	A	D	A	V	L	F	G	S	V	G	G	P	K	W	E	H	L	P	P	D	Q	Q	P	E	R	G	A	L	L	P	L	R	K	H	F	K	L	F	S	N	L	R	P	A	K	L	Y	Q	G	L	E	A	F
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?	?	?																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		C	P	L	R	A	D	I	A	A	N	G	F	D	I	L	C	V	R	E	L	T	G	G	I	Y	F	G	Q	P	K	G	R	E	G	S	G	Q	Y	E	K	A	F	D	T	E	V	Y	H	R	F	E	I	E	R	I	A	R	I	A	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																				?			?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	S	A	R	K	R	R	H	K	V	T	S	I	D	K	A	N	V	L	Q	S	S	I	L	W	R	E	I	V	N	E	I	A	T	E	Y	P	D	V	E	L	A	H	M	Y	I	D	N	A	T	M	Q	L	I	K	D	P	S	Q	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	V	L	L	C	S	N	L	F	G	D	I	L	S	D	E	C	A	M	I	T	G	S	M	G	M	L	P	S	A	S	L	N	E	Q	G	F	G	L	Y	E	P	A	G	G	S	A	P	D	I	A	G	K	N	I	A	N	P	I	A
Secondary structure
SS confidence
Disorder																					?		?		?		?	?																		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Q	I	L	S	L	A	L	L	L	R	Y	S	L	D	A	D	D	A	A	C	A	I	E	R	A	I	N	R	A	L	E	E	G	I	R	T	G	D	L	A	R	G	A	A	A	V	S	T	D	E	M	G	D	I	I	A	R	Y	V	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.
Sequence		E	G	V
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1cm7 chain A Region: 1 - 363 Aligned: 363 Modelled: 363 Confidence: 100.0% Identity: 100% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1cnz chain A Region: 1 - 363 Aligned: 363 Modelled: 363 Confidence: 100.0% Identity: 94% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1vlc chain A Region: 2 - 361 Aligned: 354 Modelled: 360 Confidence: 100.0% Identity: 57% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 3r8w chain C Region: 3 - 360 Aligned: 356 Modelled: 358 Confidence: 100.0% Identity: 52% PDB header:oxidoreductase Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic; PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution Phyre2 PDB 1v53 chain A domain 1 Region: 1 - 359 Aligned: 354 Modelled: 359 Confidence: 100.0% Identity: 51% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1a05 chain A Region: 6 - 362 Aligned: 354 Modelled: 357 Confidence: 100.0% Identity: 50% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 2d1c chain B Region: 2 - 363 Aligned: 339 Modelled: 358 Confidence: 100.0% Identity: 34% PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8 Phyre2 PDB 3u1h chain A Region: 6 - 363 Aligned: 348 Modelled: 357 Confidence: 100.0% Identity: 58% PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus Phyre2 PDB 3fmx chain X Region: 4 - 361 Aligned: 348 Modelled: 358 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase; PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh Phyre2 PDB 1g2u chain A Region: 5 - 359 Aligned: 344 Modelled: 355 Confidence: 100.0% Identity: 51% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1pb1 chain A Region: 2 - 359 Aligned: 344 Modelled: 358 Confidence: 100.0% Identity: 27% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 2d4v chain D Region: 2 - 359 Aligned: 344 Modelled: 358 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: D: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans Phyre2 PDB 1xac chain A Region: 5 - 359 Aligned: 344 Modelled: 354 Confidence: 100.0% Identity: 48% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1hqs chain A Region: 2 - 360 Aligned: 345 Modelled: 359 Confidence: 100.0% Identity: 29% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 2e0c chain A Region: 2 - 361 Aligned: 338 Modelled: 345 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution Phyre2 PDB 1wpw chain A Region: 5 - 359 Aligned: 325 Modelled: 344 Confidence: 100.0% Identity: 36% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1x0l chain B Region: 4 - 361 Aligned: 323 Modelled: 358 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: B: PDB Molecule:homoisocitrate dehydrogenase; PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus Phyre2 PDB 1w0d chain A Region: 5 - 341 Aligned: 322 Modelled: 337 Confidence: 100.0% Identity: 41% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Dimeric isocitrate & isopropylmalate dehydrogenases Phyre2 PDB 1tyo chain A Region: 2 - 362 Aligned: 346 Modelled: 361 Confidence: 100.0% Identity: 30% PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp Phyre2 PDB 3blx chain L Region: 2 - 359 Aligned: 325 Modelled: 349 Confidence: 100.0% Identity: 34% PDB header:oxidoreductase Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2; PDBTitle: yeast isocitrate dehydrogenase (apo form) Phyre2 1 d1cm7a_ 2 d1cnza_ 3 d1vlca_ 4 c3r8wC_ 5 d1v53a1 6 d1a05a_ 7 c2d1cB_ 8 c3u1hA_ 9 c3fmxX_ 10 d1g2ua_ 11 d1pb1a_ 12 c2d4vD_ 13 d1xaca_ 14 d1hqsa_ 15 c2e0cA_ 16 d1wpwa_ 17 c1x0lB_ 18 d1w0da_ 19 c1tyoA_ 20 c3blxL_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1cm7a_ 100.0 100 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 2 d1cnza_ 100.0 94 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 3 d1vlca_ 100.0 57 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 4 c3r8wC_ 100.0 52 PDB header:oxidoreductase Chain: C: PDB Molecule:3-isopropylmalate dehydrogenase 2, chloroplastic; PDBTitle: structure of 3-isopropylmalate dehydrogenase isoform 2 from2 arabidopsis thaliana at 2.2 angstrom resolution 5 d1v53a1 100.0 51 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 6 d1a05a_ 100.0 50 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 7 c2d1cB_ 100.0 34 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of tt0538 protein from thermus thermophilus hb8 8 c3u1hA_ 100.0 58 PDB header:oxidoreductase Chain: A: PDB Molecule:3-isopropylmalate dehydrogenase; PDBTitle: crystal structure of ipmdh from the last common ancestor of bacillus 9 c3fmxX_ 100.0 36 PDB header:oxidoreductase Chain: X: PDB Molecule:tartrate dehydrogenase/decarboxylase; PDBTitle: crystal structure of tartrate dehydrogenase from pseudomonas2 putida complexed with nadh 10 d1g2ua_ 100.0 51 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 11 d1pb1a_ 100.0 27 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 12 c2d4vD_ 100.0 29 PDB header:oxidoreductase Chain: D: PDB Molecule:isocitrate dehydrogenase; PDBTitle: crystal structure of nad dependent isocitrate dehydrogenase2 from acidithiobacillus thiooxidans 13 d1xaca_ 100.0 48 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 14 d1hqsa_ 100.0 29 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 15 c2e0cA_ 100.0 33 PDB header:oxidoreductase Chain: A: PDB Molecule:409aa long hypothetical nadp-dependent isocitrate PDBTitle: crystal structure of isocitrate dehydrogenase from sulfolobus tokodaii2 strain7 at 2.0 a resolution 16 d1wpwa_ 100.0 36 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 17 c1x0lB_ 100.0 38 PDB header:oxidoreductase Chain: B: PDB Molecule:homoisocitrate dehydrogenase; PDBTitle: crystal structure of tetrameric homoisocitrate dehydrogenase from an2 extreme thermophile, thermus thermophilus 18 d1w0da_ 100.0 41 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 19 c1tyoA_ 100.0 30 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile aeropyrum pernix in2 complex with etheno-nadp 20 c3blxL_ 100.0 34 PDB header:oxidoreductase Chain: L: PDB Molecule:isocitrate dehydrogenase [nad] subunit 2; PDBTitle: yeast isocitrate dehydrogenase (apo form) 21 c1zorB_ not modelled 100.0 19 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase; PDBTitle: isocitrate dehydrogenase from the hyperthermophile thermotoga maritima 22 c3blxM_ not modelled 100.0 31 PDB header:oxidoreductase Chain: M: PDB Molecule:isocitrate dehydrogenase [nad] subunit 1; PDBTitle: yeast isocitrate dehydrogenase (apo form) 23 c2uxqB_ not modelled 100.0 23 PDB header:oxidoreductase Chain: B: PDB Molecule:isocitrate dehydrogenase native; PDBTitle: isocitrate dehydrogenase from the psychrophilic bacterium2 desulfotalea psychrophila: biochemical properties and3 crystal structure analysis 24 d1lwda_ not modelled 100.0 20 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 25 d1t0la_ not modelled 100.0 21 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Dimeric isocitrate & isopropylmalate dehydrogenases 26 c2qfyE_ not modelled 100.0 21 PDB header:oxidoreductase Chain: E: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of saccharomyces cerevesiae mitochondrial nadp(+)-2 dependent isocitrate dehydrogenase in complex with a-ketoglutarate 27 c3us8A_ not modelled 100.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase [nadp]; PDBTitle: crystal structure of an isocitrate dehydrogenase from sinorhizobium2 meliloti 1021 28 c2iv0A_ not modelled 100.0 28 PDB header:oxidoreductase Chain: A: PDB Molecule:isocitrate dehydrogenase; PDBTitle: thermal stability of isocitrate dehydrogenase from2 archaeoglobus fulgidus studied by crystal structure3 analysis and engineering of chimers 29 d1ptma_ not modelled 99.0 16 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 30 c2hi1A_ not modelled 99.0 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 2; PDBTitle: the structure of a putative 4-hydroxythreonine-4-phosphate2 dehydrogenase from salmonella typhimurium. 31 d1r8ka_ not modelled 98.9 15 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:PdxA-like 32 c1yxoB_ not modelled 98.3 16 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxythreonine-4-phosphate dehydrogenase 1; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic protein pdxa2 pa0593 33 c2b0tA_ not modelled 89.5 21 PDB header:oxidoreductase Chain: A: PDB Molecule:nadp isocitrate dehydrogenase; PDBTitle: structure of monomeric nadp isocitrate dehydrogenase 34 d1itwa_ not modelled 80.9 22 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Monomeric isocitrate dehydrogenase 35 c3s40C_ not modelled 61.5 17 PDB header:transferase Chain: C: PDB Molecule:diacylglycerol kinase; PDBTitle: the crystal structure of a diacylglycerol kinases from bacillus2 anthracis str. sterne 36 c1p84E_ not modelled 61.1 32 PDB header:oxidoreductase Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur PDBTitle: hdbt inhibited yeast cytochrome bc1 complex 37 d2fpoa1 not modelled 60.6 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 38 c2fyuE_ not modelled 54.7 32 PDB header:oxidoreductase Chain: E: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit, PDBTitle: crystal structure of bovine heart mitochondrial bc1 with jg1442 inhibitor 39 d1riea_ not modelled 48.9 32 Fold:ISP domain Superfamily:ISP domain Family:Rieske iron-sulfur protein (ISP) 40 d3thia_ not modelled 44.7 16 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 41 d1oria_ not modelled 42.8 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 42 d2esra1 not modelled 42.3 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 43 c1orhA_ not modelled 41.3 14 PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 1; PDBTitle: structure of the predominant protein arginine methyltransferase prmt1 44 d3cx5e1 not modelled 40.4 32 Fold:ISP domain Superfamily:ISP domain Family:Rieske iron-sulfur protein (ISP) 45 c2fynO_ not modelled 36.5 29 PDB header:oxidoreductase Chain: O: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur PDBTitle: crystal structure analysis of the double mutant rhodobacter2 sphaeroides bc1 complex 46 c3cfxA_ not modelled 34.8 19 PDB header:transport protein Chain: A: PDB Molecule:upf0100 protein ma_0280; PDBTitle: crystal structure of m. acetivorans periplasmic binding protein2 moda/wtpa with bound tungstate 47 c2nvgA_ not modelled 34.4 26 PDB header:oxidoreductase Chain: A: PDB Molecule:ubiquinol-cytochrome c reductase iron-sulfur subunit; PDBTitle: soluble domain of rieske iron sulfur protein. 48 d2onsa1 not modelled 31.8 11 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 49 c2q62A_ not modelled 31.4 10 PDB header:flavoprotein Chain: A: PDB Molecule:arsh; PDBTitle: crystal structure of arsh from sinorhizobium meliloti 50 d2fyta1 not modelled 25.2 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 51 d1qapa1 not modelled 24.4 18 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 52 d1jq4a_ not modelled 23.0 21 Fold:beta-Grasp (ubiquitin-like) Superfamily:2Fe-2S ferredoxin-like Family:2Fe-2S ferredoxin domains from multidomain proteins 53 c3k6wA_ not modelled 22.7 19 PDB header:transport protein Chain: A: PDB Molecule:solute-binding protein ma_0280; PDBTitle: apo and ligand bound structures of moda from the archaeon2 methanosarcina acetivorans 54 c3c6kC_ not modelled 22.5 10 PDB header:transferase Chain: C: PDB Molecule:spermine synthase; PDBTitle: crystal structure of human spermine synthase in complex2 with spermidine and 5-methylthioadenosine 55 c3cfzA_ not modelled 22.5 17 PDB header:transport protein Chain: A: PDB Molecule:upf0100 protein mj1186; PDBTitle: crystal structure of m. jannaschii periplasmic binding2 protein moda/wtpa with bound tungstate 56 d1j08a1 not modelled 22.5 17 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 57 c3ku1E_ not modelled 21.1 5 PDB header:transferase Chain: E: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine 58 c2e76D_ not modelled 20.8 32 PDB header:photosynthesis Chain: D: PDB Molecule:cytochrome b6-f complex iron-sulfur subunit; PDBTitle: crystal structure of the cytochrome b6f complex with tridecyl-2 stigmatellin (tds) from m.laminosus 59 c3l0gD_ not modelled 19.3 15 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 60 c2esrB_ not modelled 18.8 10 PDB header:transferase Chain: B: PDB Molecule:methyltransferase; PDBTitle: conserved hypothetical protein- streptococcus pyogenes 61 d1f3la_ not modelled 18.0 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 62 c3lwzC_ not modelled 17.9 18 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.65 angstrom resolution crystal structure of type ii 3-2 dehydroquinate dehydratase (aroq) from yersinia pestis 63 c2pebB_ not modelled 17.8 24 PDB header:oxidoreductase Chain: B: PDB Molecule:putative dioxygenase; PDBTitle: crystal structure of a putative dioxygenase (npun_f1925) from nostoc2 punctiforme pcc 73102 at 1.46 a resolution 64 c3p9nA_ not modelled 17.8 12 PDB header:transferase Chain: A: PDB Molecule:possible methyltransferase (methylase); PDBTitle: rv2966c of m. tuberculosis is a rsmd-like methyltransferase 65 c3c0kB_ not modelled 17.7 15 PDB header:transferase Chain: B: PDB Molecule:upf0064 protein yccw; PDBTitle: crystal structure of a ribosomal rna methyltranferase 66 d1g6q1_ not modelled 17.5 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Arginine methyltransferase 67 c2huzB_ not modelled 16.8 13 PDB header:structural genomics, transferase Chain: B: PDB Molecule:glucosamine 6-phosphate n-acetyltransferase; PDBTitle: crystal structure of gnpnat1 68 d1a8la1 not modelled 16.5 12 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:PDI-like 69 c2zkiH_ not modelled 15.8 19 PDB header:transcription Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872) 70 c2dumD_ not modelled 15.0 8 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein ph0823; PDBTitle: crystal structure of hypothetical protein, ph0823 71 c3dloC_ not modelled 13.2 18 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:universal stress protein; PDBTitle: structure of universal stress protein from archaeoglobus fulgidus 72 d1atia1 not modelled 13.1 16 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 73 d2erya1 not modelled 12.8 35 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:G proteins 74 c1qpoA_ not modelled 12.7 13 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 75 d2fhpa1 not modelled 12.7 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:YhhF-like 76 c2k4mA_ not modelled 12.6 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0146 protein mth_1000; PDBTitle: solution nmr structure of m. thermoautotrophicum protein2 mth_1000, northeast structural genomics consortium target3 tr8 77 d1q77a_ not modelled 12.5 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 78 c2qv7A_ not modelled 12.5 14 PDB header:transferase Chain: A: PDB Molecule:diacylglycerol kinase dgkb; PDBTitle: crystal structure of diacylglycerol kinase dgkb in complex with adp2 and mg 79 c3cesB_ not modelled 11.3 27 PDB header:rna binding protein Chain: B: PDB Molecule:trna uridine 5-carboxymethylaminomethyl modification enzyme PDBTitle: crystal structure of e.coli mnmg (gida), a highly-conserved trna2 modifying enzyme 80 c3hgmD_ not modelled 11.1 7 PDB header:signaling protein Chain: D: PDB Molecule:universal stress protein tead; PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata 81 c2pfsA_ not modelled 11.0 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: crystal structure of universal stress protein from nitrosomonas2 europaea 82 d1cyxa_ not modelled 10.5 10 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Periplasmic domain of cytochrome c oxidase subunit II 83 c1cyxA_ not modelled 10.5 10 PDB header:electron transport Chain: A: PDB Molecule:cyoa; PDBTitle: quinol oxidase (periplasmic fragment of subunit ii with2 engineered cu-a binding site)(cyoa) 84 d1o4ua1 not modelled 10.5 18 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 85 c3pvsA_ not modelled 10.3 25 PDB header:recombination Chain: A: PDB Molecule:replication-associated recombination protein a; PDBTitle: structure and biochemical activities of escherichia coli mgsa 86 d1yo6a1 not modelled 10.0 39 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 87 d1jmva_ not modelled 10.0 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 88 d1fftb1 not modelled 9.8 10 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Periplasmic domain of cytochrome c oxidase subunit II 89 c3fg9B_ not modelled 9.8 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein of universal stress protein uspa family; PDBTitle: the crystal structure of an universal stress protein uspa2 family protein from lactobacillus plantarum wcfs1 90 d1u8sa1 not modelled 9.8 13 Fold:Ferredoxin-like Superfamily:ACT-like Family:Glycine cleavage system transcriptional repressor 91 c3b3jA_ not modelled 9.5 12 PDB header:transferase Chain: A: PDB Molecule:histone-arginine methyltransferase carm1; PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered) 92 d2ffea1 not modelled 9.3 28 Fold:CofD-like Superfamily:CofD-like Family:CofD-like 93 c2b78A_ not modelled 9.3 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein smu.776; PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans 94 c3mt0A_ not modelled 9.3 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pa1789; PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1 95 d1xmta_ not modelled 8.7 11 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT 96 d1i7na1 not modelled 8.7 16 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Synapsin domain 97 d1tq8a_ not modelled 8.6 11 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 98 d2g4ca1 not modelled 8.5 9 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 99 d2r9ga1 not modelled 8.3 18 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:MgsA/YrvN C-terminal domain-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0