Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	A	K	T	A	P	K	V	T	L	W	E	F	F	Q	Q	L	G	K	T	F	M	L	P	V	A	L	L	S	F	C	G	I	M	L	G	I	G	S	S	L	S	S	H	D	V	I	T	L	I	P	V	L	G	N	P	V	L	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?																																?	?		?	?	?	?	?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	I	F	T	W	M	S	K	I	G	S	F	A	F	S	F	L	P	V	M	F	C	I	A	I	P	L	G	L	A	R	E	N	K	G	V	A	A	F	A	G	F	I	G	Y	A	V	M	N	L	A	V	N	F	W	L	T	N	K	G
Secondary structure
SS confidence
Disorder																																																									?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	L	P	T	T	D	A	A	V	L	K	A	N	N	I	Q	S	I	L	G	I	Q	S	I	D	T	G	I	L	G	A	V	I	A	G	I	I	V	W	M	L	H	E	R	F	H	N	I	R	L	P	D	A	L	A	F	F	G	G	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?		?								?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	F	V	P	I	I	S	S	L	V	M	G	L	V	G	L	V	I	P	L	V	W	P	I	F	A	M	G	I	S	G	L	G	H	M	I	N	S	A	G	D	F	G	P	M	L	F	G	T	G	E	R	L	L	L	P	F	G	L	H
Secondary structure
SS confidence
Disorder			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	I	L	V	A	L	I	R	F	T	D	A	G	G	T	Q	E	V	C	G	Q	T	V	S	G	A	L	T	I	F	Q	A	Q	L	S	C	P	T	T	H	G	F	S	E	S	A	T	R	F	L	S	Q	G	K	M	P	A	F	L	G
Secondary structure
SS confidence
Disorder															?																						?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	L	P	G	A	A	L	A	M	Y	H	C	A	R	P	E	N	R	H	K	I	K	G	L	L	I	S	G	L	I	A	C	V	V	G	G	T	T	E	P	L	E	F	L	F	L	F	V	A	P	V	L	Y	V	I	H	A	L	L	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		G	L	G	F	T	V	M	S	V	L	G	V	T	I	G	N	T	D	G	N	I	I	D	F	V	V	F	G	I	L	H	G	L	S	T	K	W	Y	M	V	P	V	V	A	A	I	W	F	V	V	Y	Y	V	I	F	R	F	A	I	T
Secondary structure
SS confidence
Disorder																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		R	F	N	L	K	T	P	G	R	D	S	E	V	A	S	S	I	E	K	A	V	A	G	A	P	G	K	S	G	Y	N	V	P	A	I	L	E	A	L	G	G	A	D	N	I	V	S	L	D	N	C	I	T	R	L	R	L	S	V	K
Secondary structure
SS confidence
Disorder										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530
Sequence		D	M	S	L	V	N	V	Q	A	L	K	D	N	R	A	I	G	V	V	Q	L	N	Q	H	N	L	Q	V	V	I	G	P	Q	V	Q	S	V	K	D	E	M	A	G	L	M	H	T	V	Q	A
Secondary structure
SS confidence
Disorder						?																																									?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3qnq chain D Region: 1 - 438 Aligned: 418 Modelled: 434 Confidence: 100.0% Identity: 15% PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system Phyre2 PDB 3bp8 chain C domain 1 Region: 451 - 526 Aligned: 75 Modelled: 76 Confidence: 99.9% Identity: 41% Fold: Homing endonuclease-like Superfamily: Glucose permease domain IIB Family: Glucose permease domain IIB Phyre2 PDB 1iba chain A Region: 451 - 527 Aligned: 76 Modelled: 77 Confidence: 99.9% Identity: 41% PDB header:phoshphotransferase Chain: A: PDB Molecule:glucose permease; PDBTitle: glucose permease (domain iib), nmr, 11 structures Phyre2 PDB 3ipj chain B Region: 443 - 524 Aligned: 80 Modelled: 82 Confidence: 99.8% Identity: 28% PDB header:transferase Chain: B: PDB Molecule:pts system, iiabc component; PDBTitle: the crystal structure of one domain of the pts system, iiabc component2 from clostridium difficile Phyre2 PDB 3mp7 chain A Region: 340 - 436 Aligned: 96 Modelled: 97 Confidence: 47.0% Identity: 16% PDB header:protein transport Chain: A: PDB Molecule:preprotein translocase subunit secy; PDBTitle: lateral opening of a translocon upon entry of protein suggests the2 mechanism of insertion into membranes Phyre2 PDB 1xme chain A domain 1 Region: 16 - 460 Aligned: 438 Modelled: 445 Confidence: 45.8% Identity: 13% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 3b9y chain A Region: 295 - 464 Aligned: 170 Modelled: 170 Confidence: 39.8% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:ammonium transporter family rh-like protein; PDBTitle: crystal structure of the nitrosomonas europaea rh protein Phyre2 PDB 2hnh chain A Region: 325 - 347 Aligned: 23 Modelled: 23 Confidence: 38.1% Identity: 35% PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii alpha subunit; PDBTitle: crystal structure of the catalytic alpha subunit of e. coli2 replicative dna polymerase iii Phyre2 PDB 1gpr chain A Region: 462 - 514 Aligned: 52 Modelled: 53 Confidence: 37.8% Identity: 8% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 2dla chain B Region: 446 - 487 Aligned: 41 Modelled: 42 Confidence: 36.9% Identity: 29% PDB header:replication Chain: B: PDB Molecule:397aa long hypothetical protein; PDBTitle: primase large subunit amino terminal domain from pyrococcus horikoshii Phyre2 PDB 2gpr chain A Region: 478 - 514 Aligned: 37 Modelled: 37 Confidence: 33.6% Identity: 3% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 1gla chain F Region: 478 - 514 Aligned: 37 Modelled: 37 Confidence: 27.6% Identity: 5% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 2f3g chain A Region: 471 - 514 Aligned: 44 Modelled: 44 Confidence: 27.6% Identity: 9% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 3e0d chain A Region: 325 - 347 Aligned: 23 Modelled: 23 Confidence: 25.9% Identity: 35% PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase iii subunit alpha; PDBTitle: insights into the replisome from the crystral structure of2 the ternary complex of the eubacterial dna polymerase iii3 alpha-subunit Phyre2 PDB 2rdd chain B Region: 404 - 421 Aligned: 18 Modelled: 18 Confidence: 25.7% Identity: 39% PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. Phyre2 PDB 1nh8 chain A domain 2 Region: 478 - 499 Aligned: 22 Modelled: 22 Confidence: 24.9% Identity: 18% Fold: Ferredoxin-like Superfamily: GlnB-like Family: ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain Phyre2 PDB 3zqs chain B Region: 461 - 483 Aligned: 23 Modelled: 23 Confidence: 18.8% Identity: 35% PDB header:ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase fancl; PDBTitle: human fancl central domain Phyre2 PDB 2nr9 chain A domain 1 Region: 94 - 170 Aligned: 77 Modelled: 77 Confidence: 18.5% Identity: 17% Fold: Rhomboid-like Superfamily: Rhomboid-like Family: Rhomboid-like Phyre2 PDB 1h3d chain A domain 2 Region: 478 - 502 Aligned: 25 Modelled: 25 Confidence: 16.6% Identity: 24% Fold: Ferredoxin-like Superfamily: GlnB-like Family: ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain Phyre2 PDB 1l0w chain A domain 3 Region: 453 - 496 Aligned: 44 Modelled: 44 Confidence: 16.2% Identity: 14% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 1 c3qnqD_ 2 d3bp8c1 3 c1ibaA_ 4 c3ipjB_ 5 c3mp7A_ 6 d1xmea1 7 c3b9yA_ 8 c2hnhA_ 9 d1gpra_ 10 c2dlaB_ 11 d2gpra_ 12 d1glaf_ 13 d2f3ga_ 14 c3e0dA_ 15 c2rddB_ 16 d1nh8a2 17 c3zqsB_ 18 d2nr9a1 19 d1h3da2 20 d1l0wa3 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3qnqD_ 100.0 15 PDB header:membrane protein, transport protein Chain: D: PDB Molecule:pts system, cellobiose-specific iic component; PDBTitle: crystal structure of the transporter chbc, the iic component from the2 n,n'-diacetylchitobiose-specific phosphotransferase system 2 d3bp8c1 99.9 41 Fold:Homing endonuclease-like Superfamily:Glucose permease domain IIB Family:Glucose permease domain IIB 3 c1ibaA_ 99.9 41 PDB header:phoshphotransferase Chain: A: PDB Molecule:glucose permease; PDBTitle: glucose permease (domain iib), nmr, 11 structures 4 c3ipjB_ 99.8 28 PDB header:transferase Chain: B: PDB Molecule:pts system, iiabc component; PDBTitle: the crystal structure of one domain of the pts system, iiabc component2 from clostridium difficile 5 c3mp7A_ 47.0 16 PDB header:protein transport Chain: A: PDB Molecule:preprotein translocase subunit secy; PDBTitle: lateral opening of a translocon upon entry of protein suggests the2 mechanism of insertion into membranes 6 d1xmea1 45.8 13 Fold:Cytochrome c oxidase subunit I-like Superfamily:Cytochrome c oxidase subunit I-like Family:Cytochrome c oxidase subunit I-like 7 c3b9yA_ 39.8 13 PDB header:transport protein Chain: A: PDB Molecule:ammonium transporter family rh-like protein; PDBTitle: crystal structure of the nitrosomonas europaea rh protein 8 c2hnhA_ 38.1 35 PDB header:transferase Chain: A: PDB Molecule:dna polymerase iii alpha subunit; PDBTitle: crystal structure of the catalytic alpha subunit of e. coli2 replicative dna polymerase iii 9 d1gpra_ 37.8 8 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 10 c2dlaB_ 36.9 29 PDB header:replication Chain: B: PDB Molecule:397aa long hypothetical protein; PDBTitle: primase large subunit amino terminal domain from pyrococcus horikoshii 11 d2gpra_ 33.6 3 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 12 d1glaf_ 27.6 5 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 13 d2f3ga_ 27.6 9 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 14 c3e0dA_ 25.9 35 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase iii subunit alpha; PDBTitle: insights into the replisome from the crystral structure of2 the ternary complex of the eubacterial dna polymerase iii3 alpha-subunit 15 c2rddB_ 25.7 39 PDB header:membrane protein/transport protein Chain: B: PDB Molecule:upf0092 membrane protein yajc; PDBTitle: x-ray crystal structure of acrb in complex with a novel2 transmembrane helix. 16 d1nh8a2 24.9 18 Fold:Ferredoxin-like Superfamily:GlnB-like Family:ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain 17 c3zqsB_ 18.8 35 PDB header:ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase fancl; PDBTitle: human fancl central domain 18 d2nr9a1 18.5 17 Fold:Rhomboid-like Superfamily:Rhomboid-like Family:Rhomboid-like 19 d1h3da2 16.6 24 Fold:Ferredoxin-like Superfamily:GlnB-like Family:ATP phosphoribosyltransferase (ATP-PRTase, HisG), regulatory C-terminal domain 20 d1l0wa3 16.2 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 21 d1osda_ not modelled 15.2 17 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 22 d1cpza_ not modelled 14.9 21 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 23 d1st6a5 not modelled 14.6 19 Fold:Four-helical up-and-down bundle Superfamily:alpha-catenin/vinculin-like Family:alpha-catenin/vinculin 24 c2ci2I_ not modelled 14.1 30 PDB header:proteinase inhibitor (chymotrypsin) Chain: I: PDB Molecule:chymotrypsin inhibitor 2; PDBTitle: crystal and molecular structure of the serine proteinase2 inhibitor ci-2 from barley seeds 25 c1p68A_ not modelled 14.1 55 PDB header:de novo protein Chain: A: PDB Molecule:de novo designed protein s-824; PDBTitle: solution structure of s-824, a de novo designed four helix2 bundle 26 d2cfua2 not modelled 13.2 19 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Alkylsulfatase-like 27 d1q8la_ not modelled 13.0 12 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 28 d1kvja_ not modelled 12.6 14 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 29 c2ga7A_ not modelled 12.6 21 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the copper(i) form of the third metal-2 binding domain of atp7a protein (menkes disease protein) 30 d1fzda_ not modelled 12.4 29 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 31 d1j7na3 not modelled 12.1 15 Fold:ADP-ribosylation Superfamily:ADP-ribosylation Family:ADP-ribosylating toxins 32 c2ldiA_ not modelled 11.7 19 PDB header:hydrolase Chain: A: PDB Molecule:zinc-transporting atpase; PDBTitle: nmr solution structure of ziaan sub mutant 33 d2axtk1 not modelled 11.4 40 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein K, PsbK Family:PsbK-like 34 c2cfuA_ not modelled 11.2 19 PDB header:hydrolase Chain: A: PDB Molecule:sdsa1; PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid. 35 c1yjrA_ not modelled 11.1 12 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the apo form of the sixth soluble2 domain a69p mutant of menkes protein 36 c3f2cA_ not modelled 10.6 26 PDB header:transferase/dna Chain: A: PDB Molecule:geobacillus kaustophilus dna polc; PDBTitle: dna polymerase polc from geobacillus kaustophilus complex with dna,2 dgtp and mn 37 d1u7ga_ not modelled 10.3 3 Fold:Ammonium transporter Superfamily:Ammonium transporter Family:Ammonium transporter 38 d2ifqa1 not modelled 10.3 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 39 d1f9qa_ not modelled 10.1 10 Fold:IL8-like Superfamily:Interleukin 8-like chemokines Family:Interleukin 8-like chemokines 40 c2w2eA_ not modelled 10.1 7 PDB header:membrane protein Chain: A: PDB Molecule:aquaporin; PDBTitle: 1.15 angstrom crystal structure of p.pastoris aquaporin,2 aqy1, in a closed conformation at ph 3.5 41 d2a9da1 not modelled 10.0 43 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Molybdenum-containing oxidoreductases-like dimerisation domain 42 d1p6ta1 not modelled 9.7 12 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 43 c3a0bK_ not modelled 9.7 33 PDB header:electron transport Chain: K: PDB Molecule:photosystem ii reaction center protein k; PDBTitle: crystal structure of br-substituted photosystem ii complex 44 c3a0bk_ not modelled 9.7 33 PDB header:electron transport Chain: K: PDB Molecule:photosystem ii reaction center protein k; PDBTitle: crystal structure of br-substituted photosystem ii complex 45 d2qifa1 not modelled 9.2 21 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 46 c2l3mA_ not modelled 9.0 17 PDB header:metal binding protein Chain: A: PDB Molecule:copper-ion-binding protein; PDBTitle: solution structure of the putative copper-ion-binding protein from2 bacillus anthracis str. ames 47 d3pvia_ not modelled 9.0 16 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Restriction endonuclease PvuII 48 d1afia_ not modelled 9.0 19 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 49 c3e6qL_ not modelled 8.9 24 PDB header:isomerase Chain: L: PDB Molecule:putative 5-carboxymethyl-2-hydroxymuconate isomerase; PDBTitle: putative 5-carboxymethyl-2-hydroxymuconate isomerase from pseudomonas2 aeruginosa. 50 c3a0hk_ not modelled 8.7 33 PDB header:electron transport Chain: K: PDB Molecule:photosystem ii reaction center protein k; PDBTitle: crystal structure of i-substituted photosystem ii complex 51 d1pfma_ not modelled 8.5 10 Fold:IL8-like Superfamily:Interleukin 8-like chemokines Family:Interleukin 8-like chemokines 52 d1fida_ not modelled 8.3 24 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 53 d2axti1 not modelled 7.8 23 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein I, PsbI Family:PsbI-like 54 d1plfa_ not modelled 7.7 10 Fold:IL8-like Superfamily:Interleukin 8-like chemokines Family:Interleukin 8-like chemokines 55 c3eh4A_ not modelled 7.7 13 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase subunit 1; PDBTitle: structure of the reduced form of cytochrome ba3 oxidase from thermus2 thermophilus 56 c1vbwA_ not modelled 7.5 24 PDB header:protein binding Chain: A: PDB Molecule:trypsin inhibitor bgit; PDBTitle: crystal structure of bitter gourd trypsin inhibitor 57 d1lwuc1 not modelled 7.5 31 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 58 d1wf3a2 not modelled 7.4 21 Fold:Alpha-lytic protease prodomain-like Superfamily:Prokaryotic type KH domain (KH-domain type II) Family:Prokaryotic type KH domain (KH-domain type II) 59 d1ypci_ not modelled 7.4 29 Fold:CI-2 family of serine protease inhibitors Superfamily:CI-2 family of serine protease inhibitors Family:CI-2 family of serine protease inhibitors 60 d1f9ra_ not modelled 7.2 10 Fold:IL8-like Superfamily:Interleukin 8-like chemokines Family:Interleukin 8-like chemokines 61 c3l7qD_ not modelled 7.2 16 PDB header:translation Chain: D: PDB Molecule:putative translation initiation inhibitor, aldr regulator- PDBTitle: crystal structure of aldr from streptococcus mutans 62 d1to2i_ not modelled 7.0 29 Fold:CI-2 family of serine protease inhibitors Superfamily:CI-2 family of serine protease inhibitors Family:CI-2 family of serine protease inhibitors 63 c1q1kA_ not modelled 7.0 17 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase; PDBTitle: structure of atp-phosphoribosyltransferase from e. coli complexed with2 pr-atp 64 d1h7sa2 not modelled 6.9 37 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 65 c1u5tB_ not modelled 6.9 14 PDB header:transport protein Chain: B: PDB Molecule:defective in vacuolar protein sorting; vps36p; PDBTitle: structure of the escrt-ii endosomal trafficking complex 66 c1hgvA_ not modelled 6.9 10 PDB header:virus Chain: A: PDB Molecule:ph75 inovirus major coat protein; PDBTitle: filamentous bacteriophage ph75 67 d2snii_ not modelled 6.9 30 Fold:CI-2 family of serine protease inhibitors Superfamily:CI-2 family of serine protease inhibitors Family:CI-2 family of serine protease inhibitors 68 c3dxsX_ not modelled 6.8 19 PDB header:hydrolase Chain: X: PDB Molecule:copper-transporting atpase ran1; PDBTitle: crystal structure of a copper binding domain from hma7, a p-2 type atpase 69 d1z9ha1 not modelled 6.8 17 Fold:GST C-terminal domain-like Superfamily:GST C-terminal domain-like Family:Glutathione S-transferase (GST), C-terminal domain 70 d1dwma_ not modelled 6.7 31 Fold:CI-2 family of serine protease inhibitors Superfamily:CI-2 family of serine protease inhibitors Family:CI-2 family of serine protease inhibitors 71 c1y3kA_ not modelled 6.6 14 PDB header:hydrolase Chain: A: PDB Molecule:copper-transporting atpase 1; PDBTitle: solution structure of the apo form of the fifth domain of2 menkes protein 72 c1tinA_ not modelled 6.6 35 PDB header:serine protease inhibitor Chain: A: PDB Molecule:trypsin inhibitor v; PDBTitle: three-dimensional structure in solution of cucurbita maxima2 trypsin inhibitor-v determined by nmr spectroscopy 73 d1bkna2 not modelled 6.6 26 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:DNA gyrase/MutL, N-terminal domain 74 d1s6ua_ not modelled 6.5 12 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 75 d1l0wa2 not modelled 6.4 16 Fold:DCoH-like Superfamily:GAD domain-like Family:GAD domain 76 c3hd7A_ not modelled 6.4 15 PDB header:exocytosis Chain: A: PDB Molecule:vesicle-associated membrane protein 2; PDBTitle: helical extension of the neuronal snare complex into the membrane,2 spacegroup c 1 2 1 77 d1egla_ not modelled 6.3 18 Fold:CI-2 family of serine protease inhibitors Superfamily:CI-2 family of serine protease inhibitors Family:CI-2 family of serine protease inhibitors 78 c3qd1X_ not modelled 6.3 26 PDB header:sugar binding protein Chain: X: PDB Molecule:platelet binding protein gspb; PDBTitle: gspb plus alpha-2,3-sialyl (1-thioethyl)galactose 79 c2j61B_ not modelled 6.2 35 PDB header:lectin Chain: B: PDB Molecule:ficolin-2; PDBTitle: l-ficolin complexed to n-acetylglucosamine (forme c) 80 d1lwub1 not modelled 6.2 19 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 81 d1m1jc1 not modelled 6.2 30 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 82 d1wffa_ not modelled 6.1 30 Fold:AN1-like Zinc finger Superfamily:AN1-like Zinc finger Family:AN1-like Zinc finger 83 d1xrga_ not modelled 6.1 16 Fold:Bacillus chorismate mutase-like Superfamily:YjgF-like Family:YjgF/L-PSP 84 d2aw0a_ not modelled 6.1 17 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 85 d1wgla_ not modelled 6.0 21 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:CUE domain 86 c2hqnA_ not modelled 6.0 21 PDB header:signaling protein Chain: A: PDB Molecule:putative transcriptional regulator; PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism 87 c1yg0A_ not modelled 5.9 14 PDB header:metal transport Chain: A: PDB Molecule:cop associated protein; PDBTitle: solution structure of apo-copp from helicobacter pylori 88 c3cjsA_ not modelled 5.9 15 PDB header:transferase/ribosomal protein Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase; PDBTitle: minimal recognition complex between prma and ribosomal protein l11 89 c2ofhX_ not modelled 5.8 17 PDB header:hydrolase, membrane protein Chain: X: PDB Molecule:zinc-transporting atpase; PDBTitle: solution structure of the n-terminal domain of the zinc(ii) atpase2 ziaa in its apo form 90 c1a0oH_ not modelled 5.7 15 PDB header:chemotaxis Chain: H: PDB Molecule:chea; PDBTitle: chey-binding domain of chea in complex with chey 91 d1jmkc_ not modelled 5.7 9 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Thioesterase domain of polypeptide, polyketide and fatty acid synthases 92 c2kncA_ not modelled 5.7 10 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 93 c1deqF_ not modelled 5.6 24 PDB header: PDB COMPND: 94 c1w7pD_ not modelled 5.6 14 PDB header:protein transport Chain: D: PDB Molecule:vps36p, ylr417w; PDBTitle: the crystal structure of endosomal complex escrt-ii2 (vps22/vps25/vps36) 95 d1qaha_ not modelled 5.6 23 Fold:Bacillus chorismate mutase-like Superfamily:YjgF-like Family:YjgF/L-PSP 96 d1p6ta2 not modelled 5.6 14 Fold:Ferredoxin-like Superfamily:HMA, heavy metal-associated domain Family:HMA, heavy metal-associated domain 97 c1b9uA_ not modelled 5.6 22 PDB header:hydrolase Chain: A: PDB Molecule:protein (atp synthase); PDBTitle: membrane domain of the subunit b of the e.coli atp synthase 98 c3bvhC_ not modelled 5.5 24 PDB header:blood clotting Chain: C: PDB Molecule:fibrinogen gamma chain; PDBTitle: crystal structure of recombinant gammad364a fibrinogen fragment d with2 the peptide ligand gly-pro-arg-pro-amide 99 c2hpcF_ not modelled 5.5 24 PDB header:blood clotting Chain: F: PDB Molecule:fibrinogen, gamma polypeptide; PDBTitle: crystal structure of fragment d from human fibrinogen complexed with2 gly-pro-arg-pro-amide.

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0