Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	G	S	N	T	A	I	S	R	R	R	L	L	Q	G	A	G	A	M	W	L	L	S	V	S	Q	V	S	L	A	A	V	S	Q	V	V	A	V	R	V	W	P	A	S	S	Y	T	R	V	T	V	E	S	N	R	Q	L	K	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																			?	?	?	?	?	?	?	?	?	?	?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	Q	F	A	L	S	N	P	E	R	V	V	V	D	I	E	D	V	N	L	N	S	V	L	K	G	M	A	A	Q	I	R	A	D	D	P	F	I	K	S	A	R	V	G	Q	F	D	P	Q	T	V	R	M	V	F	E	L	K	Q	N
Secondary structure
SS confidence
Disorder																				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	K	P	Q	L	F	A	L	A	P	V	A	G	F	K	E	R	L	V	M	D	L	Y	P	A	N	A	Q	D	M	Q	D	P	L	L	A	L	L	E	D	Y	N	K	G	D	L	E	K	Q	V	P	P	A	Q	S	G	P	Q	P	G
Secondary structure
SS confidence
Disorder		?	?	?					?	?	?	?	?	?											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	A	G	R	D	R	P	I	V	I	M	L	D	P	G	H	G	G	E	D	S	G	A	V	G	K	Y	K	T	R	E	K	D	V	V	L	Q	I	A	R	R	L	R	S	L	I	E	K	E	G	N	M	K	V	Y	M	T	R	N	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?																	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	I	F	I	P	L	Q	V	R	V	A	K	A	Q	K	Q	R	A	D	L	F	V	S	I	H	A	D	A	F	T	S	R	Q	P	S	G	S	S	V	F	A	L	S	T	K	G	A	T	S	T	A	A	K	Y	L	A	Q	T	Q	N
Secondary structure
SS confidence
Disorder																																	?													?	?	?	?	?										?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		A	S	D	L	I	G	G	V	S	K	S	G	D	R	Y	V	D	H	T	M	F	D	M	V	Q	S	L	T	I	A	D	S	L	K	F	G	K	A	V	L	N	K	L	G	K	I	N	K	L	H	K	N	Q	V	E	Q	A	G	F	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?													?	?	?																			?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.
Sequence		V	L	K	A	P	D	I	P	S	I	L	V	E	T	A	F	I	S	N	V	E	E	E	R	K	L	K	T	A	T	F	Q	Q	E	V	A	E	S	I	L	A	G	I	K	A	Y	F	A	D	G	A	T	L	A	R	R	G
Secondary structure
SS confidence
Disorder																											?	?	?																						?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ne8 chain A Region: 186 - 415 Aligned: 223 Modelled: 228 Confidence: 100.0% Identity: 38% PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: the crystal structure of a domain from n-acetylmuramoyl-l-alanine2 amidase of bartonella henselae str. houston-1 Phyre2 PDB 1jwq chain A Region: 188 - 407 Aligned: 174 Modelled: 174 Confidence: 100.0% Identity: 35% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 1xov chain A Region: 189 - 407 Aligned: 169 Modelled: 175 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:ply protein; PDBTitle: the crystal structure of the listeria monocytogenes bacteriophage psa2 endolysin plypsa Phyre2 PDB 3czx chain A Region: 186 - 407 Aligned: 170 Modelled: 171 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:putative n-acetylmuramoyl-l-alanine amidase; PDBTitle: the crystal structure of the putative n-acetylmuramoyl-l-2 alanine amidase from neisseria meningitidis Phyre2 PDB 1xov chain A domain 2 Region: 189 - 404 Aligned: 166 Modelled: 172 Confidence: 100.0% Identity: 19% Fold: Phosphorylase/hydrolase-like Superfamily: Zn-dependent exopeptidases Family: N-acetylmuramoyl-L-alanine amidase-like Phyre2 PDB 3qay chain C Region: 187 - 406 Aligned: 169 Modelled: 174 Confidence: 100.0% Identity: 25% PDB header:lyase Chain: C: PDB Molecule:endolysin; PDBTitle: catalytic domain of cd27l endolysin targeting clostridia difficile Phyre2 PDB 2gfq chain A domain 1 Region: 366 - 413 Aligned: 43 Modelled: 48 Confidence: 87.2% Identity: 21% Fold: Phosphorylase/hydrolase-like Superfamily: AF0625-like Family: AF0625-like Phyre2 PDB 2gfq chain C Region: 366 - 406 Aligned: 36 Modelled: 41 Confidence: 85.0% Identity: 25% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:upf0204 protein ph0006; PDBTitle: structure of protein of unknown function ph0006 from pyrococcus2 horikoshii Phyre2 PDB 2qvp chain C Region: 180 - 400 Aligned: 179 Modelled: 192 Confidence: 84.2% Identity: 15% PDB header:hydrolase Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative metallopeptidase (sama_0725) from2 shewanella amazonensis sb2b at 2.00 a resolution Phyre2 PDB 1yqe chain A domain 1 Region: 366 - 403 Aligned: 33 Modelled: 38 Confidence: 82.4% Identity: 33% Fold: Phosphorylase/hydrolase-like Superfamily: AF0625-like Family: AF0625-like Phyre2 PDB 1c4g chain B Region: 184 - 268 Aligned: 66 Modelled: 66 Confidence: 61.5% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:protein (alpha-d-glucose 1-phosphate PDBTitle: phosphoglucomutase vanadate based transition state analog2 complex Phyre2 PDB 2fuv chain B Region: 186 - 268 Aligned: 63 Modelled: 64 Confidence: 58.8% Identity: 19% PDB header:isomerase Chain: B: PDB Molecule:phosphoglucomutase; PDBTitle: phosphoglucomutase from salmonella typhimurium. Phyre2 PDB 1wqa chain B Region: 184 - 268 Aligned: 65 Modelled: 84 Confidence: 47.4% Identity: 29% PDB header:isomerase Chain: B: PDB Molecule:phospho-sugar mutase; PDBTitle: crystal structure of pyrococcus horikoshii2 phosphomannomutase/phosphoglucomutase complexed with mg2+ Phyre2 PDB 1nyr chain A domain 1 Region: 212 - 264 Aligned: 49 Modelled: 53 Confidence: 46.0% Identity: 18% Fold: Anticodon-binding domain-like Superfamily: Class II aaRS ABD-related Family: Anticodon-binding domain of Class II aaRS Phyre2 PDB 2f7l chain A Region: 186 - 268 Aligned: 63 Modelled: 64 Confidence: 44.3% Identity: 24% PDB header:isomerase Chain: A: PDB Molecule:455aa long hypothetical phospho-sugar mutase; PDBTitle: crystal structure of sulfolobus tokodaii2 phosphomannomutase/phosphoglucomutase Phyre2 PDB 1wwp chain A Region: 373 - 408 Aligned: 36 Modelled: 36 Confidence: 43.3% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ttha0636; PDBTitle: crystal structure of ttk003001694 from thermus thermophilus2 hb8 Phyre2 PDB 1fx0 chain B domain 1 Region: 205 - 256 Aligned: 52 Modelled: 52 Confidence: 40.8% Identity: 15% Fold: Left-handed superhelix Superfamily: C-terminal domain of alpha and beta subunits of F1 ATP synthase Family: C-terminal domain of alpha and beta subunits of F1 ATP synthase Phyre2 PDB 3i3w chain B Region: 184 - 268 Aligned: 65 Modelled: 66 Confidence: 40.6% Identity: 22% PDB header:isomerase Chain: B: PDB Molecule:phosphoglucosamine mutase; PDBTitle: structure of a phosphoglucosamine mutase from francisella tularensis Phyre2 PDB 1kfi chain A domain 2 Region: 184 - 197 Aligned: 14 Modelled: 14 Confidence: 38.5% Identity: 21% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 3l2n chain A Region: 251 - 407 Aligned: 125 Modelled: 126 Confidence: 35.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:peptidase m14, carboxypeptidase a; PDBTitle: crystal structure of putative carboxypeptidase a (yp_562911.1) from2 shewanella denitrificans os-217 at 2.39 a resolution Phyre2 1 c3ne8A_ 2 d1jwqa_ 3 c1xovA_ 4 c3czxA_ 5 d1xova2 6 c3qayC_ 7 d2gfqa1 8 c2gfqC_ 9 c2qvpC_ 10 d1yqea1 11 c1c4gB_ 12 c2fuvB_ 13 c1wqaB_ 14 d1nyra1 15 c2f7lA_ 16 c1wwpA_ 17 d1fx0b1 18 c3i3wB_ 19 d1kfia2 20 c3l2nA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ne8A_ 100.0 38 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: the crystal structure of a domain from n-acetylmuramoyl-l-alanine2 amidase of bartonella henselae str. houston-1 2 d1jwqa_ 100.0 35 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:N-acetylmuramoyl-L-alanine amidase-like 3 c1xovA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:ply protein; PDBTitle: the crystal structure of the listeria monocytogenes bacteriophage psa2 endolysin plypsa 4 c3czxA_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:putative n-acetylmuramoyl-l-alanine amidase; PDBTitle: the crystal structure of the putative n-acetylmuramoyl-l-2 alanine amidase from neisseria meningitidis 5 d1xova2 100.0 19 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:N-acetylmuramoyl-L-alanine amidase-like 6 c3qayC_ 100.0 25 PDB header:lyase Chain: C: PDB Molecule:endolysin; PDBTitle: catalytic domain of cd27l endolysin targeting clostridia difficile 7 d2gfqa1 87.2 21 Fold:Phosphorylase/hydrolase-like Superfamily:AF0625-like Family:AF0625-like 8 c2gfqC_ 85.0 25 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:upf0204 protein ph0006; PDBTitle: structure of protein of unknown function ph0006 from pyrococcus2 horikoshii 9 c2qvpC_ 84.2 15 PDB header:hydrolase Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative metallopeptidase (sama_0725) from2 shewanella amazonensis sb2b at 2.00 a resolution 10 d1yqea1 82.4 33 Fold:Phosphorylase/hydrolase-like Superfamily:AF0625-like Family:AF0625-like 11 c1c4gB_ 61.5 18 PDB header:transferase Chain: B: PDB Molecule:protein (alpha-d-glucose 1-phosphate PDBTitle: phosphoglucomutase vanadate based transition state analog2 complex 12 c2fuvB_ 58.8 19 PDB header:isomerase Chain: B: PDB Molecule:phosphoglucomutase; PDBTitle: phosphoglucomutase from salmonella typhimurium. 13 c1wqaB_ 47.4 29 PDB header:isomerase Chain: B: PDB Molecule:phospho-sugar mutase; PDBTitle: crystal structure of pyrococcus horikoshii2 phosphomannomutase/phosphoglucomutase complexed with mg2+ 14 d1nyra1 46.0 18 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 15 c2f7lA_ 44.3 24 PDB header:isomerase Chain: A: PDB Molecule:455aa long hypothetical phospho-sugar mutase; PDBTitle: crystal structure of sulfolobus tokodaii2 phosphomannomutase/phosphoglucomutase 16 c1wwpA_ 43.3 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ttha0636; PDBTitle: crystal structure of ttk003001694 from thermus thermophilus2 hb8 17 d1fx0b1 40.8 15 Fold:Left-handed superhelix Superfamily:C-terminal domain of alpha and beta subunits of F1 ATP synthase Family:C-terminal domain of alpha and beta subunits of F1 ATP synthase 18 c3i3wB_ 40.6 22 PDB header:isomerase Chain: B: PDB Molecule:phosphoglucosamine mutase; PDBTitle: structure of a phosphoglucosamine mutase from francisella tularensis 19 d1kfia2 38.5 21 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 20 c3l2nA_ 35.9 18 PDB header:hydrolase Chain: A: PDB Molecule:peptidase m14, carboxypeptidase a; PDBTitle: crystal structure of putative carboxypeptidase a (yp_562911.1) from2 shewanella denitrificans os-217 at 2.39 a resolution 21 d1skye1 not modelled 35.8 18 Fold:Left-handed superhelix Superfamily:C-terminal domain of alpha and beta subunits of F1 ATP synthase Family:C-terminal domain of alpha and beta subunits of F1 ATP synthase 22 d3pmga2 not modelled 34.2 14 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 23 c3nh8A_ not modelled 33.7 15 PDB header:hydrolase Chain: A: PDB Molecule:aspartoacylase-2; PDBTitle: crystal structure of murine aminoacylase 3 in complex with n-acetyl-s-2 1,2-dichlorovinyl-l-cysteine 24 c3r1jB_ not modelled 31.3 16 PDB header:oxidoreductase Chain: B: PDB Molecule:alpha-ketoglutarate-dependent taurine dioxygenase; PDBTitle: crystal structure of alpha-ketoglutarate-dependent taurine dioxygenase2 from mycobacterium avium, native form 25 d1ad1a_ not modelled 29.9 75 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 26 c1nj2A_ not modelled 29.5 23 PDB header:ligase Chain: A: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus 27 d2g4ca1 not modelled 29.4 15 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 28 c3k2kA_ not modelled 29.2 18 PDB header:hydrolase Chain: A: PDB Molecule:putative carboxypeptidase; PDBTitle: crystal structure of putative carboxypeptidase (yp_103406.1) from2 burkholderia mallei atcc 23344 at 2.49 a resolution 29 c3bghB_ not modelled 27.6 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative neuraminyllactose-binding hemagglutinin homolog; PDBTitle: crystal structure of putative neuraminyllactose-binding hemagglutinin2 homolog from helicobacter pylori 30 d1wu7a1 not modelled 24.5 18 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 31 d1nj8a1 not modelled 24.3 16 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 32 d1nj1a1 not modelled 23.8 22 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 33 c2y5sA_ not modelled 23.8 63 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate. 34 d1qf6a1 not modelled 23.0 7 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 35 d1g5ha1 not modelled 22.4 17 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 36 c3l80A_ not modelled 21.8 14 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c; PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159 37 c2dzaA_ not modelled 21.5 63 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 38 d1p5dx2 not modelled 21.5 34 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 39 d1kija1 not modelled 20.2 13 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:DNA gyrase/MutL, second domain 40 d1u83a_ not modelled 18.9 24 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 41 c1u83A_ not modelled 18.9 24 PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis 42 d1eyea_ not modelled 18.7 44 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 43 c1kfiA_ not modelled 18.4 21 PDB header:isomerase Chain: A: PDB Molecule:phosphoglucomutase 1; PDBTitle: crystal structure of the exocytosis-sensitive2 phosphoprotein, pp63/parafusin (phosphoglucomutase) from3 paramecium 44 c2vp8A_ not modelled 18.1 38 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase 2; PDBTitle: structure of mycobacterium tuberculosis rv1207 45 c2ae3A_ not modelled 17.9 14 PDB header:hydrolase Chain: A: PDB Molecule:glutaryl 7-aminocephalosporanic acid acylase; PDBTitle: glutaryl 7-aminocephalosporanic acid acylase: mutational study of2 activation mechanism 46 c2ronA_ not modelled 17.8 15 PDB header:hydrolase Chain: A: PDB Molecule:surfactin synthetase thioesterase subunit; PDBTitle: the external thioesterase of the surfactin-synthetase 47 c2gx8B_ not modelled 17.8 23 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:nif3-related protein; PDBTitle: the crystal stucture of bacillus cereus protein related to nif3 48 d1tx2a_ not modelled 17.8 47 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 49 c1tx2A_ not modelled 17.8 47 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 50 d2b3ya2 not modelled 17.5 20 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 51 c2e85B_ not modelled 17.3 17 PDB header:hydrolase Chain: B: PDB Molecule:hydrogenase 3 maturation protease; PDBTitle: crystal structure of the hydrogenase 3 maturation protease 52 c3ibtA_ not modelled 16.4 18 PDB header:oxidoreductase Chain: A: PDB Molecule:1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase; PDBTitle: structure of 1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase (qdo) 53 d1ei1a1 not modelled 15.7 19 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:DNA gyrase/MutL, second domain 54 c1k8wA_ not modelled 15.6 55 PDB header:lyase/rna Chain: A: PDB Molecule:trna pseudouridine synthase b; PDBTitle: crystal structure of the e. coli pseudouridine synthase2 trub bound to a t stem-loop rna 55 d1ccwa_ not modelled 15.4 17 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 56 c2vf7B_ not modelled 15.4 28 PDB header:dna-binding protein Chain: B: PDB Molecule:excinuclease abc, subunit a.; PDBTitle: crystal structure of uvra2 from deinococcus radiodurans 57 d2gx8a1 not modelled 14.7 23 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 58 c1ze2B_ not modelled 14.5 58 PDB header:lyase/rna Chain: B: PDB Molecule:trna pseudouridine synthase b; PDBTitle: conformational change of pseudouridine 55 synthase upon its2 association with rna substrate 59 c3netB_ not modelled 14.2 15 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120 60 c3t4cD_ not modelled 14.0 21 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria 61 d1qe0a1 not modelled 13.7 13 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 62 c3cwvB_ not modelled 13.7 3 PDB header:isomerase Chain: B: PDB Molecule:dna gyrase, b subunit, truncated; PDBTitle: crystal structure of b-subunit of the dna gyrase from myxococcus2 xanthus 63 c2qj8B_ not modelled 13.6 19 PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution 64 d3bula2 not modelled 13.4 17 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 65 c2i4lC_ not modelled 13.2 11 PDB header:ligase Chain: C: PDB Molecule:proline-trna ligase; PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase 66 c5acnA_ not modelled 13.2 20 PDB header:lyase(carbon-oxygen) Chain: A: PDB Molecule:aconitase; PDBTitle: structure of activated aconitase. formation of the (4fe-4s)2 cluster in the crystal 67 d1c4xa_ not modelled 13.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 68 c2yxbA_ not modelled 12.9 18 PDB header:isomerase Chain: A: PDB Molecule:coenzyme b12-dependent mutase; PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix 69 d1acoa2 not modelled 12.8 20 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 70 d2bodx1 not modelled 12.7 29 Fold:7-stranded beta/alpha barrel Superfamily:Glycosyl hydrolases family 6, cellulases Family:Glycosyl hydrolases family 6, cellulases 71 d2fsja1 not modelled 12.4 19 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Ta0583-like 72 d1joga_ not modelled 12.3 25 Fold:Four-helical up-and-down bundle Superfamily:Nucleotidyltransferase substrate binding subunit/domain Family:Family 1 bi-partite nucleotidyltransferase subunit 73 d1cr5a2 not modelled 12.2 21 Fold:Cdc48 domain 2-like Superfamily:Cdc48 domain 2-like Family:Cdc48 domain 2-like 74 c2wj4B_ not modelled 11.9 26 PDB header:oxidoreductase Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase; PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine 75 d2ey4a2 not modelled 11.8 55 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 76 c1g5hA_ not modelled 11.5 17 PDB header:dna binding protein Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit; PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma 77 d1kjna_ not modelled 11.4 20 Fold:Hypothetical protein MTH777 (MT0777) Superfamily:Hypothetical protein MTH777 (MT0777) Family:Hypothetical protein MTH777 (MT0777) 78 d1ifya_ not modelled 11.3 12 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:UBA domain 79 c3cdxB_ not modelled 11.2 20 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 80 c3lnuA_ not modelled 11.1 6 PDB header:isomerase Chain: A: PDB Molecule:topoisomerase iv subunit b; PDBTitle: crystal structure of pare subunit 81 d2fywa1 not modelled 10.9 28 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 82 c3dyvA_ not modelled 10.9 31 PDB header:hydrolase Chain: A: PDB Molecule:esterase d; PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism 83 c2b3yB_ not modelled 10.9 20 PDB header:lyase Chain: B: PDB Molecule:iron-responsive element binding protein 1; PDBTitle: structure of a monoclinic crystal form of human cytosolic aconitase2 (irp1) 84 d1sgva2 not modelled 10.8 55 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 85 d1uoza_ not modelled 10.4 31 Fold:7-stranded beta/alpha barrel Superfamily:Glycosyl hydrolases family 6, cellulases Family:Glycosyl hydrolases family 6, cellulases 86 d1uuqa_ not modelled 10.3 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 87 c1uz4A_ not modelled 10.3 14 PDB header:hydrolase Chain: A: PDB Molecule:man5a; PDBTitle: common inhibition of beta-glucosidase and beta-mannosidase2 by isofagomine lactam reflects different conformational3 intineraries for glucoside and mannoside hydrolysis 88 d2apoa2 not modelled 10.3 55 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 89 d1k8wa5 not modelled 10.0 55 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 90 d1r3ea2 not modelled 10.0 64 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 91 c3qvmA_ not modelled 10.0 20 PDB header:hydrolase Chain: A: PDB Molecule:olei00960; PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica 92 c2dlnA_ not modelled 9.9 18 PDB header:ligase(peptidoglycan synthesis) Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution 93 c3a64A_ not modelled 9.8 38 PDB header:hydrolase Chain: A: PDB Molecule:cellobiohydrolase; PDBTitle: crystal structure of cccel6c, a glycoside hydrolase family 62 enzyme, from coprinopsis cinerea 94 c2i9oA_ not modelled 9.7 21 PDB header:de novo protein Chain: A: PDB Molecule:mhb8a peptide; PDBTitle: design of bivalent miniprotein consisting of two2 independent elements, a b-hairpin peptide and a-helix3 peptide, tethered by eight glycines 95 c2daiA_ not modelled 9.5 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ubiquitin associated domain containing 1; PDBTitle: solution structure of the first uba domain in the human2 ubiquitin associated domain containing 1 (ubadc1) 96 c1y37A_ not modelled 9.5 20 PDB header:hydrolase Chain: A: PDB Molecule:fluoroacetate dehalogenase; PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1 97 c1y80A_ not modelled 9.4 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted cobalamin binding protein; PDBTitle: structure of a corrinoid (factor iiim)-binding protein from2 moorella thermoacetica 98 d1s16a1 not modelled 9.4 10 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:DNA gyrase/MutL, second domain 99 c3pdkB_ not modelled 9.3 17 PDB header:isomerase Chain: B: PDB Molecule:phosphoglucosamine mutase; PDBTitle: crystal structure of phosphoglucosamine mutase from b. anthracis

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0