Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	F	Y	F	R	K	E	C	P	L	N	S	G	Y	L	R	K	N	R	P	E	K	P	D	G	R	R	A	V	L	R	S	Q	V	L	E	L	H	G	I	S	H	G	S	A	G	A	R	S	I	A	T	M	A	T	R	R	G	Y
Secondary structure
SS confidence
Disorder		?	?	?																?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	M	G	R	W	L	A	G	R	L	M	K	E	L	G	L	V	S	C	Q	Q	P	T	H	R	Y	K	R	G	G	H	E	H	V	A	I	P	N	Y	L	E	R	Q	F	A	V	T	E	P	N	Q	V	W	C	G	D	V	T	Y	I
Secondary structure
SS confidence
Disorder																			?			?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	T	G	K	R	W	A	Y	L	A	V	V	L	D	L	F	A	R	K	P	V	G	W	A	M	S	F	S	P	D	S	R	L	T	M	K	A	L	E	M	A	W	E	T	R	G	K	P	V	G	V	M	F	Q	A	I	K	A	V	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.
Sequence		I	R	A	G	S	S	G	S	Y	C	G	D	T	G	S	G	R	V
Secondary structure
SS confidence
Disorder																?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1c0m chain A Region: 106 - 194 Aligned: 86 Modelled: 89 Confidence: 99.6% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:protein (integrase); PDBTitle: crystal structure of rsv two-domain integrase Phyre2 PDB 1asu chain A Region: 102 - 197 Aligned: 93 Modelled: 96 Confidence: 99.5% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Retroviral integrase, catalytic domain Phyre2 PDB 1cxq chain A Region: 107 - 197 Aligned: 88 Modelled: 91 Confidence: 99.5% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Retroviral integrase, catalytic domain Phyre2 PDB 1c0m chain A domain 2 Region: 103 - 194 Aligned: 89 Modelled: 92 Confidence: 99.4% Identity: 18% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Retroviral integrase, catalytic domain Phyre2 PDB 1bco chain A domain 2 Region: 108 - 194 Aligned: 87 Modelled: 87 Confidence: 99.3% Identity: 16% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: mu transposase, core domain Phyre2 PDB 1exq chain A Region: 107 - 194 Aligned: 79 Modelled: 88 Confidence: 99.0% Identity: 11% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Retroviral integrase, catalytic domain Phyre2 PDB 3nf9 chain A Region: 109 - 198 Aligned: 82 Modelled: 90 Confidence: 99.0% Identity: 11% PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:integrase; PDBTitle: structural basis for a new mechanism of inhibition of hiv integrase2 identified by fragment screening and structure based design Phyre2 PDB 1c6v chain A Region: 107 - 197 Aligned: 83 Modelled: 91 Confidence: 99.0% Identity: 10% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Retroviral integrase, catalytic domain Phyre2 PDB 1ex4 chain A Region: 107 - 194 Aligned: 79 Modelled: 88 Confidence: 98.9% Identity: 11% PDB header:viral protein Chain: A: PDB Molecule:integrase; PDBTitle: hiv-1 integrase catalytic core and c-terminal domain Phyre2 PDB 3f9k chain V Region: 109 - 197 Aligned: 81 Modelled: 89 Confidence: 98.9% Identity: 10% PDB header:viral protein, recombination Chain: V: PDB Molecule:integrase; PDBTitle: two domain fragment of hiv-2 integrase in complex with ledgf ibd Phyre2 PDB 1k6y chain B Region: 32 - 197 Aligned: 124 Modelled: 140 Confidence: 98.9% Identity: 9% PDB header:transferase Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of a two-domain fragment of hiv-1 integrase Phyre2 PDB 3kks chain B Region: 111 - 194 Aligned: 76 Modelled: 84 Confidence: 98.7% Identity: 11% PDB header:dna binding protein Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of catalytic core domain of biv integrase in crystal2 form ii Phyre2 PDB 1bco chain A Region: 125 - 195 Aligned: 71 Modelled: 71 Confidence: 98.7% Identity: 14% PDB header:transposase Chain: A: PDB Molecule:bacteriophage mu transposase; PDBTitle: bacteriophage mu transposase core domain Phyre2 PDB 3hpg chain C Region: 32 - 194 Aligned: 121 Modelled: 137 Confidence: 98.6% Identity: 13% PDB header:transferase Chain: C: PDB Molecule:integrase; PDBTitle: visna virus integrase (residues 1-219) in complex with ledgf2 ibd: examples of open integrase dimer-dimer interfaces Phyre2 PDB 3dlr chain A Region: 107 - 194 Aligned: 84 Modelled: 88 Confidence: 98.5% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:integrase; PDBTitle: crystal structure of the catalytic core domain from pfv2 integrase Phyre2 PDB 1hyv chain A Region: 109 - 189 Aligned: 72 Modelled: 81 Confidence: 98.5% Identity: 10% Fold: Ribonuclease H-like motif Superfamily: Ribonuclease H-like Family: Retroviral integrase, catalytic domain Phyre2 PDB 3l2t chain B Region: 106 - 194 Aligned: 85 Modelled: 89 Confidence: 98.3% Identity: 13% PDB header:recombination/dna Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of the prototype foamy virus (pfv) intasome in2 complex with magnesium and mk0518 (raltegravir) Phyre2 PDB 3hos chain A Region: 32 - 194 Aligned: 157 Modelled: 163 Confidence: 97.4% Identity: 11% PDB header:transferase, dna binding protein/dna Chain: A: PDB Molecule:transposable element mariner, complete cds; PDBTitle: crystal structure of the mariner mos1 paired end complex with mg Phyre2 PDB 3v4g chain A Region: 27 - 166 Aligned: 132 Modelled: 140 Confidence: 95.4% Identity: 14% PDB header:dna binding protein Chain: A: PDB Molecule:arginine repressor; PDBTitle: 1.60 angstrom resolution crystal structure of an arginine repressor2 from vibrio vulnificus cmcp6 Phyre2 PDB 1u78 chain A Region: 7 - 75 Aligned: 64 Modelled: 69 Confidence: 94.6% Identity: 11% PDB header:dna binding protein/dna Chain: A: PDB Molecule:transposable element tc3 transposase; PDBTitle: structure of the bipartite dna-binding domain of tc32 transposase bound to transposon dna Phyre2 1 c1c0mA_ 2 d1asua_ 3 d1cxqa_ 4 d1c0ma2 5 d1bcoa2 6 d1exqa_ 7 c3nf9A_ 8 d1c6va_ 9 c1ex4A_ 10 c3f9kV_ 11 c1k6yB_ 12 c3kksB_ 13 c1bcoA_ 14 c3hpgC_ 15 c3dlrA_ 16 d1hyva_ 17 c3l2tB_ 18 c3hosA_ 19 c3v4gA_ 20 c1u78A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1c0mA_ 99.6 19 PDB header:transferase Chain: A: PDB Molecule:protein (integrase); PDBTitle: crystal structure of rsv two-domain integrase 2 d1asua_ 99.5 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 3 d1cxqa_ 99.5 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 4 d1c0ma2 99.4 18 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 5 d1bcoa2 99.3 16 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:mu transposase, core domain 6 d1exqa_ 99.0 11 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 7 c3nf9A_ 99.0 11 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:integrase; PDBTitle: structural basis for a new mechanism of inhibition of hiv integrase2 identified by fragment screening and structure based design 8 d1c6va_ 99.0 10 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 9 c1ex4A_ 98.9 11 PDB header:viral protein Chain: A: PDB Molecule:integrase; PDBTitle: hiv-1 integrase catalytic core and c-terminal domain 10 c3f9kV_ 98.9 10 PDB header:viral protein, recombination Chain: V: PDB Molecule:integrase; PDBTitle: two domain fragment of hiv-2 integrase in complex with ledgf ibd 11 c1k6yB_ 98.9 9 PDB header:transferase Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of a two-domain fragment of hiv-1 integrase 12 c3kksB_ 98.7 11 PDB header:dna binding protein Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of catalytic core domain of biv integrase in crystal2 form ii 13 c1bcoA_ 98.7 14 PDB header:transposase Chain: A: PDB Molecule:bacteriophage mu transposase; PDBTitle: bacteriophage mu transposase core domain 14 c3hpgC_ 98.6 13 PDB header:transferase Chain: C: PDB Molecule:integrase; PDBTitle: visna virus integrase (residues 1-219) in complex with ledgf2 ibd: examples of open integrase dimer-dimer interfaces 15 c3dlrA_ 98.5 14 PDB header:transferase Chain: A: PDB Molecule:integrase; PDBTitle: crystal structure of the catalytic core domain from pfv2 integrase 16 d1hyva_ 98.5 10 Fold:Ribonuclease H-like motif Superfamily:Ribonuclease H-like Family:Retroviral integrase, catalytic domain 17 c3l2tB_ 98.3 13 PDB header:recombination/dna Chain: B: PDB Molecule:integrase; PDBTitle: crystal structure of the prototype foamy virus (pfv) intasome in2 complex with magnesium and mk0518 (raltegravir) 18 c3hosA_ 97.4 11 PDB header:transferase, dna binding protein/dna Chain: A: PDB Molecule:transposable element mariner, complete cds; PDBTitle: crystal structure of the mariner mos1 paired end complex with mg 19 c3v4gA_ 95.4 14 PDB header:dna binding protein Chain: A: PDB Molecule:arginine repressor; PDBTitle: 1.60 angstrom resolution crystal structure of an arginine repressor2 from vibrio vulnificus cmcp6 20 c1u78A_ 94.6 11 PDB header:dna binding protein/dna Chain: A: PDB Molecule:transposable element tc3 transposase; PDBTitle: structure of the bipartite dna-binding domain of tc32 transposase bound to transposon dna 21 d1aoya_ not modelled 93.8 11 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 22 c1b4aA_ not modelled 93.2 16 PDB header:repressor Chain: A: PDB Molecule:arginine repressor; PDBTitle: structure of the arginine repressor from bacillus stearothermophilus 23 c3ereD_ not modelled 92.1 17 PDB header:dna binding protein/dna Chain: D: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the arginine repressor protein from mycobacterium2 tuberculosis in complex with the dna operator 24 c6paxA_ not modelled 92.0 12 PDB header:gene regulation/dna Chain: A: PDB Molecule:homeobox protein pax-6; PDBTitle: crystal structure of the human pax-6 paired domain-dna2 complex reveals a general model for pax protein-dna3 interactions 25 d1pdnc_ not modelled 87.1 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Paired domain 26 d1b4aa1 not modelled 86.6 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 27 d2p5ka1 not modelled 86.2 21 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 28 d1f9na1 not modelled 85.6 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Arginine repressor (ArgR), N-terminal DNA-binding domain 29 c3mwmA_ not modelled 84.3 19 PDB header:transcription Chain: A: PDB Molecule:putative metal uptake regulation protein; PDBTitle: graded expression of zinc-responsive genes through two regulatory2 zinc-binding sites in zur 30 c2o03A_ not modelled 83.4 17 PDB header:gene regulation Chain: A: PDB Molecule:probable zinc uptake regulation protein furb; PDBTitle: crystal structure of furb from m. tuberculosis- a zinc uptake2 regulator 31 c2o8kA_ not modelled 83.0 17 PDB header:transcription/dna Chain: A: PDB Molecule:rna polymerase sigma factor rpon; PDBTitle: nmr structure of the sigma-54 rpon domain bound to the-242 promoter element 32 c2fe3B_ not modelled 80.8 16 PDB header:dna binding protein Chain: B: PDB Molecule:peroxide operon regulator; PDBTitle: the crystal structure of bacillus subtilis perr-zn reveals a novel2 zn(cys)4 structural redox switch 33 c2xigA_ not modelled 79.6 14 PDB header:transcription Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: the structure of the helicobacter pylori ferric uptake2 regulator fur reveals three functional metal binding sites 34 d1mzba_ not modelled 79.5 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:FUR-like 35 c2w57A_ not modelled 72.8 16 PDB header:metal transport Chain: A: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the vibrio cholerae ferric uptake2 regulator (fur) reveals structural rearrangement of the3 dna-binding domains 36 c2r0qF_ not modelled 72.8 13 PDB header:recombination/dna Chain: F: PDB Molecule:putative transposon tn552 dna-invertase bin3; PDBTitle: crystal structure of a serine recombinase- dna regulatory2 complex 37 c3f2kB_ not modelled 68.3 11 PDB header:transferase Chain: B: PDB Molecule:histone-lysine n-methyltransferase setmar; PDBTitle: structure of the transposase domain of human histone-lysine2 n-methyltransferase setmar 38 c2fu4B_ not modelled 66.8 16 PDB header:dna binding protein Chain: B: PDB Molecule:ferric uptake regulation protein; PDBTitle: crystal structure of the dna binding domain of e.coli fur (ferric2 uptake regulator) 39 d1nkua_ not modelled 64.4 23 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:3-Methyladenine DNA glycosylase I (Tag) 40 d1stza1 not modelled 63.7 9 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Heat-inducible transcription repressor HrcA, N-terminal domain 41 c2jg6A_ not modelled 62.6 17 PDB header:hydrolase Chain: A: PDB Molecule:dna-3-methyladenine glycosidase; PDBTitle: crystal structure of a 3-methyladenine dna glycosylase i2 from staphylococcus aureus 42 c3eyyA_ not modelled 56.4 19 PDB header:transport Chain: A: PDB Molecule:putative iron uptake regulatory protein; PDBTitle: structural basis for the specialization of nur, a nickel-2 specific fur homologue, in metal sensing and dna3 recognition 43 c2xzmO_ not modelled 55.3 13 PDB header:ribosome Chain: O: PDB Molecule:rps13e; PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1 44 c2f7tA_ not modelled 46.5 11 PDB header:dna binding protein Chain: A: PDB Molecule:mos1 transposase; PDBTitle: crystal structure of the catalytic domain of mos1 mariner2 transposase 45 d1u17a1 not modelled 43.6 8 Fold:Lipocalins Superfamily:Lipocalins Family:Retinol binding protein-like 46 c1hlvA_ not modelled 42.4 20 PDB header:dna binding protein/dna Chain: A: PDB Molecule:major centromere autoantigen b; PDBTitle: crystal structure of cenp-b(1-129) complexed with the cenp-2 b box dna 47 d1x8qa_ not modelled 39.6 6 Fold:Lipocalins Superfamily:Lipocalins Family:Retinol binding protein-like 48 d2fi9a1 not modelled 35.2 5 Fold:MTH938-like Superfamily:MTH938-like Family:MTH938-like 49 d2fvta1 not modelled 33.8 6 Fold:MTH938-like Superfamily:MTH938-like Family:MTH938-like 50 d1nhpa3 not modelled 22.6 16 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 51 c2i8bB_ not modelled 22.3 12 PDB header:viral protein Chain: B: PDB Molecule:minor nucleoprotein vp30; PDBTitle: crystal structure of the c-terminal domain of ebola virus vp30 52 c3r1fO_ not modelled 20.8 11 PDB header:transcription Chain: O: PDB Molecule:esx-1 secretion-associated regulator espr; PDBTitle: crystal structure of a key regulator of virulence in mycobacterium2 tuberculosis 53 d1dxla3 not modelled 20.0 10 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 54 d1ebda3 not modelled 19.2 17 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 55 c2rpiA_ not modelled 18.7 11 PDB header:hydrolase Chain: A: PDB Molecule:ribonuclease h; PDBTitle: the nmr structure of the submillisecond folding2 intermediate of the thermus thermophilus ribonuclease h 56 d3grsa3 not modelled 18.2 16 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 57 d1gesa3 not modelled 15.2 12 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 58 d1ekja_ not modelled 15.0 16 Fold:Resolvase-like Superfamily:beta-carbonic anhydrase, cab Family:beta-carbonic anhydrase, cab 59 d1pm1x_ not modelled 14.4 9 Fold:Lipocalins Superfamily:Lipocalins Family:Retinol binding protein-like 60 d1lvla3 not modelled 13.3 14 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 61 c3p9kD_ not modelled 12.5 8 PDB header:transferase Chain: D: PDB Molecule:caffeic acid o-methyltransferase; PDBTitle: crystal structure of perennial ryegrass lpomt1 complexed with s-2 adenosyl-l-homocysteine and coniferaldehyde 62 d1y1xa_ not modelled 12.4 9 Fold:EF Hand-like Superfamily:EF-hand Family:Penta-EF-hand proteins 63 c2jsoA_ not modelled 11.6 8 PDB header:signaling protein Chain: A: PDB Molecule:polymyxin resistance protein pmrd; PDBTitle: antimicrobial resistance protein 64 c3izbO_ not modelled 11.6 16 PDB header:ribosome Chain: O: PDB Molecule:40s ribosomal protein rps13 (s15p); PDBTitle: localization of the small subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 65 d1lpfa3 not modelled 10.6 12 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 66 d2i52a1 not modelled 10.4 10 Fold:MK0786-like Superfamily:MK0786-like Family:MK0786-like 67 c3lasA_ not modelled 10.2 11 PDB header:lyase Chain: A: PDB Molecule:putative carbonic anhydrase; PDBTitle: crystal structure of carbonic anhydrase from streptococcus mutans to2 1.4 angstrom resolution 68 d2coba1 not modelled 9.9 9 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Psq domain 69 d1v59a3 not modelled 9.9 12 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 70 d1ixsb1 not modelled 9.3 22 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Helicase DNA-binding domain 71 d1aoga3 not modelled 9.3 3 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 72 d1u3em2 not modelled 8.9 11 Fold:DNA-binding domain of intron-encoded endonucleases Superfamily:DNA-binding domain of intron-encoded endonucleases Family:DNA-binding domain of intron-encoded endonucleases 73 c2qv5A_ not modelled 8.9 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu2773; PDBTitle: crystal structure of uncharacterized protein atu2773 from2 agrobacterium tumefaciens c58 74 c1fpqA_ not modelled 8.3 5 PDB header:transferase Chain: A: PDB Molecule:isoliquiritigenin 2'-o-methyltransferase; PDBTitle: crystal structure analysis of selenomethionine substituted chalcone o-2 methyltransferase 75 d1onfa3 not modelled 8.3 14 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 76 d1ojta3 not modelled 8.1 12 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 77 c2a5vB_ not modelled 8.0 8 PDB header:lyase Chain: B: PDB Molecule:carbonic anhydrase (carbonate dehydratase) (carbonic PDBTitle: crystal structure of m. tuberculosis beta carbonic anhydrase, rv3588c,2 tetrameric form 78 c2j89A_ not modelled 8.0 7 PDB header:oxidoreductase Chain: A: PDB Molecule:methionine sulfoxide reductase a; PDBTitle: functional and structural aspects of poplar cytosolic and2 plastidial type a methionine sulfoxide reductases 79 d1ej5a_ not modelled 7.9 20 Fold:Wiscott-Aldrich syndrome protein, WASP, C-terminal domain Superfamily:Wiscott-Aldrich syndrome protein, WASP, C-terminal domain Family:Wiscott-Aldrich syndrome protein, WASP, C-terminal domain 80 d1ixrc1 not modelled 7.8 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Helicase DNA-binding domain 81 d3lada3 not modelled 7.6 14 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 82 d1ff3a_ not modelled 7.4 18 Fold:Ferredoxin-like Superfamily:Peptide methionine sulfoxide reductase Family:Peptide methionine sulfoxide reductase 83 d1feca3 not modelled 7.4 10 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:FAD/NAD-linked reductases, dimerisation (C-terminal) domain Family:FAD/NAD-linked reductases, dimerisation (C-terminal) domain 84 d1gkab_ not modelled 7.3 16 Fold:Lipocalins Superfamily:Lipocalins Family:Retinol binding protein-like 85 d1in4a1 not modelled 7.2 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Helicase DNA-binding domain 86 c2k27A_ not modelled 7.2 13 PDB header:transcription regulator Chain: A: PDB Molecule:paired box protein pax-8; PDBTitle: solution structure of human pax8 paired box domain 87 c1ylkA_ not modelled 7.2 4 PDB header:unknown function Chain: A: PDB Molecule:hypothetical protein rv1284/mt1322; PDBTitle: crystal structure of rv1284 from mycobacterium tuberculosis in complex2 with thiocyanate 88 c1fvaA_ not modelled 7.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:peptide methionine sulfoxide reductase; PDBTitle: crystal structure of bovine methionine sulfoxide reductase 89 c2e4jA_ not modelled 7.0 10 PDB header:isomerase Chain: A: PDB Molecule:prostaglandin-h2 d-isomerase; PDBTitle: solution structure of mouse lipocalin-type prostaglandin d2 synthase 90 c1zgaA_ not modelled 6.9 9 PDB header:plant protein, transferase Chain: A: PDB Molecule:isoflavanone 4'-o-methyltransferase'; PDBTitle: crystal structure of isoflavanone 4'-o-methyltransferase complexed2 with (+)-6a-hydroxymaackiain 91 c3g43F_ not modelled 6.9 12 PDB header:metal binding protein Chain: F: PDB Molecule:voltage-dependent l-type calcium channel subunit PDBTitle: crystal structure of the calmodulin-bound cav1.2 c-terminal2 regulatory domain dimer 92 c3elkA_ not modelled 6.8 10 PDB header:transcription regulator Chain: A: PDB Molecule:putative transcriptional regulator ta0346; PDBTitle: crystal structure of putative transcriptional regulator ta0346 from2 thermoplasma acidophilum 93 c3klbA_ not modelled 6.8 17 PDB header:flavoprotein Chain: A: PDB Molecule:putative flavoprotein; PDBTitle: crystal structure of putative flavoprotein in complex with fmn2 (yp_213683.1) from bacteroides fragilis nctc 9343 at 1.75 a3 resolution 94 d1fp2a2 not modelled 6.6 5 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Plant O-methyltransferase, C-terminal domain 95 c3icrA_ not modelled 6.4 6 PDB header:oxidoreductase Chain: A: PDB Molecule:coenzyme a-disulfide reductase; PDBTitle: crystal structure of oxidized bacillus anthracis coadr-rhd 96 c3eyxB_ not modelled 6.3 14 PDB header:lyase Chain: B: PDB Molecule:carbonic anhydrase; PDBTitle: crystal structure of carbonic anhydrase nce103 from2 saccharomyces cerevisiae 97 c2a8cE_ not modelled 6.2 5 PDB header:lyase Chain: E: PDB Molecule:carbonic anhydrase 2; PDBTitle: haemophilus influenzae beta-carbonic anhydrase 98 c3ucoB_ not modelled 6.1 13 PDB header:lyase/lyase inhibitor Chain: B: PDB Molecule:carbonic anhydrase; PDBTitle: coccomyxa beta-carbonic anhydrase in complex with iodide 99 c3hhhA_ not modelled 5.9 14 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, padr family; PDBTitle: crystal structure of transcriptional regulator, a member of padr2 family, from enterococcus faecalis v583

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0