PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c1ex4A_

Fold library id	PDB Header	Molecule	Title
c1ex4A_	PDB header: viral protein	Chain: A: PDB Molecule: integrase;	PDBTitle: hiv-1 integrase catalytic core and c-terminal domain

Links to external resources
Added to library: Tue Mar 16 12:23:45 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S S P G I W Q L D C T H L E G K V I L V A V H V A S G Y I E A E V I P A E T G Q E T A Y F L L K L A G R W P V K T I H T D N G S N F T G A T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G T T
T T T
S S S S T T S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence V R A A C D W A G I K Q E D G I P Q S Q G V V E S M N K E L K K I I G Q V R D Q A E H L K T A V Q M A V F I H N K K R K G G I G G Y S A G E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T T
S S G G G
S S S
S S S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence R I V D I I A T D I Q T K E L Q K Q I T K I Q N F R V Y Y R D S R N S L W K G P A K L L W K G E G A V V I Q D N S D I K V V P R R K A K I I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S
S S
S S
S S
G G G

. .

Sequence R D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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Phyre2 is part of Genome3D

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	S	P	G	I	W	Q	L	D	C	T	H	L	E	G	K	V	I	L	V	A	V	H	V	A	S	G	Y	I	E	A	E	V	I	P	A	E	T	G	Q	E	T	A	Y	F	L	L	K	L	A	G	R	W	P	V	K	T	I	H	T	D	N	G	S	N	F	T	G	A	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		G	G	G										T	T									T	T	T									S	S	S	S	T	T													S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	V	R	A	A	C	D	W	A	G	I	K	Q	E	D	G	I	P	Q	S	Q	G	V	V	E	S	M	N	K	E	L	K	K	I	I	G	Q	V	R	D	Q	A	E	H	L	K	T	A	V	Q	M	A	V	F	I	H	N	K	K	R	K	G	G	I	G	G	Y	S	A	G	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	T	T										S	S																		G	G	G		S	S	S																S	S	S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	R	I	V	D	I	I	A	T	D	I	Q	T	K	E	L	Q	K	Q	I	T	K	I	Q	N	F	R	V	Y	Y	R	D	S	R	N	S	L	W	K	G	P	A	K	L	L	W	K	G	E	G	A	V	V	I	Q	D	N	S	D	I	K	V	V	P	R	R	K	A	K	I	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T												T	S							S	S															S	S							S	S							G	G	G
	.	.
Sequence	R	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)