Email l.a.kelley@imperial.ac.uk Description P76491 Date Thu Jan 5 12:23:33 GMT 2012 Unique Job ID 78736b11405522cd

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2paqa1 100.0 96 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 2 c3mzoA_ 100.0 26 PDB header:hydrolase Chain: A: PDB Molecule:lin2634 protein; PDBTitle: crystal structure of a hd-domain phosphohydrolase (lin2634) from2 listeria innocua at 1.98 a resolution 3 c3kh1B_ 100.0 22 PDB header:hydrolase Chain: B: PDB Molecule:predicted metal-dependent phosphohydrolase; PDBTitle: crystal structure of predicted metal-dependent2 phosphohydrolase (zp_00055740.2) from magnetospirillum3 magnetotacticum ms-1 at 1.37 a resolution 4 d1xx7a_ 100.0 26 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 5 c2cqzA_ 100.0 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:177aa long hypothetical protein; PDBTitle: crystal structure of ph0347 protein from pyrococcus horikoshii ot3 6 d1ynba1 100.0 20 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 7 d2gz4a1 99.9 26 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 8 d2pq7a1 99.1 13 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 9 d2qgsa1 98.9 18 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 10 d3b57a1 98.9 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 11 d2pjqa1 98.9 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 12 c3gw7A_ 98.8 21 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein yedj; PDBTitle: crystal structure of a metal-dependent phosphohydrolase2 with conserved hd domain (yedj) from escherichia coli in3 complex with nickel ions. northeast structural genomics4 consortium target er63 13 d3dtoa1 98.8 15 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 14 d3djba1 98.7 20 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 15 c2ogiA_ 98.6 16 PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein sag1661; PDBTitle: crystal structure of a putative metal dependent phosphohydrolase2 (sag1661) from streptococcus agalactiae serogroup v at 1.85 a3 resolution 16 c3ccgA_ 98.5 19 PDB header:hydrolase Chain: A: PDB Molecule:hd superfamily hydrolase; PDBTitle: crystal structure of predicted hd superfamily hydrolase involved in2 nad metabolism (np_347894.1) from clostridium acetobutylicum at 1.503 a resolution 17 c2o08B_ 98.5 13 PDB header:hydrolase Chain: B: PDB Molecule:bh1327 protein; PDBTitle: crystal structure of a putative hd superfamily hydrolase (bh1327) from2 bacillus halodurans at 1.90 a resolution 18 c3m1tA_ 97.6 13 PDB header:hydrolase Chain: A: PDB Molecule:putative phosphohydrolase; PDBTitle: crystal structure of putative phosphohydrolase (yp_929327.1) from2 shewanella amazonensis sb2b at 1.62 a resolution 19 c2dqbB_ 97.5 18 PDB header:hydrolase, dna binding protein Chain: B: PDB Molecule:deoxyguanosinetriphosphate triphosphohydrolase, putative; PDBTitle: crystal structure of dntp triphosphohydrolase from thermus2 thermophilus hb8, which is homologous to dgtp triphosphohydrolase 20 c3i7aA_ 97.4 13 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent phosphohydrolase; PDBTitle: crystal structure of putative metal-dependent phosphohydrolase2 (yp_926882.1) from shewanella amazonensis sb2b at 2.06 a resolution 21 c3hc1A_ not modelled 97.3 23 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized hdod domain protein; PDBTitle: crystal structure of hdod domain protein with unknown function2 (np_953345.1) from geobacter sulfurreducens at 1.90 a resolution 22 c3memA_ not modelled 96.9 15 PDB header:signaling protein Chain: A: PDB Molecule:putative signal transduction protein; PDBTitle: crystal structure of a putative signal transduction protein2 (maqu_0641) from marinobacter aquaeolei vt8 at 2.25 a resolution 23 c3nqwB_ not modelled 96.8 17 PDB header:hydrolase Chain: B: PDB Molecule:cg11900; PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses 24 c3nr1A_ not modelled 96.7 20 PDB header:hydrolase Chain: A: PDB Molecule:hd domain-containing protein 3; PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses 25 d2heka1 not modelled 96.5 22 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 26 c2o6iA_ not modelled 96.5 23 PDB header:hydrolase Chain: A: PDB Molecule:hd domain protein; PDBTitle: structure of an enterococcus faecalis hd domain phosphohydrolase 27 d2o6ia1 not modelled 96.5 23 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 28 d1vqra_ not modelled 96.4 10 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:modified HD domain 29 c2q14A_ not modelled 96.3 21 PDB header:hydrolase Chain: A: PDB Molecule:phosphohydrolase; PDBTitle: crystal structure of phosphohydrolase (bt4208) from bacteroides2 thetaiotaomicron vpi-5482 at 2.20 a resolution 30 c3u1nC_ not modelled 96.3 24 PDB header:hydrolase Chain: C: PDB Molecule:sam domain and hd domain-containing protein 1; PDBTitle: structure of the catalytic core of human samhd1 31 c3ljvA_ not modelled 95.7 15 PDB header:transcription Chain: A: PDB Molecule:mmoq response regulator; PDBTitle: crystal structure of mmoq response regulator (fragment 29-302) from2 methylococcus capsulatus str. bath, northeast structural genomics3 consortium target mcr175m 32 c2pgsA_ not modelled 95.2 19 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyguanosinetriphosphate triphosphohydrolase; PDBTitle: crystal structure of a putative deoxyguanosinetriphosphate2 triphosphohydrolase from pseudomonas syringae pv. phaseolicola 1448a 33 d1vj7a1 not modelled 94.0 21 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 34 c3bg2A_ not modelled 93.7 32 PDB header:hydrolase Chain: A: PDB Molecule:dgtp triphosphohydrolase; PDBTitle: crystal structure of deoxyguanosinetriphosphate triphosphohydrolase2 from flavobacterium sp. med217 35 c1vj7B_ not modelled 93.3 23 PDB header:hydrolase, transferase Chain: B: PDB Molecule:bifunctional rela/spot; PDBTitle: crystal structure of the bifunctional catalytic fragment of relseq,2 the rela/spot homolog from streptococcus equisimilis. 36 c3skdA_ not modelled 88.6 22 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein tthb187; PDBTitle: crystal structure of the thermus thermophilus cas3 hd domain in the2 presence of ni2+ 37 c3kq5A_ not modelled 84.6 7 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical cytosolic protein; PDBTitle: crystal structure of an uncharacterized protein from coxiella burnetii 38 d1u6za1 not modelled 78.5 12 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:Ppx associated domain 39 c1xotB_ not modelled 70.9 18 PDB header:hydrolase Chain: B: PDB Molecule:camp-specific 3',5'-cyclic phosphodiesterase 4b; PDBTitle: catalytic domain of human phosphodiesterase 4b in complex with2 vardenafil 40 d1y2ka1 not modelled 70.8 14 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 41 c3m5fA_ not modelled 66.1 15 PDB header:hydrolase Chain: A: PDB Molecule:metal dependent phosphohydrolase; PDBTitle: structure of mj0384, a cas3 protein from methanocaldococcus jannaschii 42 d1taza_ not modelled 65.3 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 43 c2r8qA_ not modelled 63.2 12 PDB header:hydrolase Chain: A: PDB Molecule:class i phosphodiesterase pdeb1; PDBTitle: structure of lmjpdeb1 in complex with ibmx 44 c1xozA_ not modelled 63.1 17 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: catalytic domain of human phosphodiesterase 5a in complex2 with tadalafil 45 d3dy8a1 not modelled 60.5 14 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 46 d3bxda1 not modelled 59.6 24 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:MioX-like 47 c2huoA_ not modelled 59.6 24 PDB header:oxidoreductase Chain: A: PDB Molecule:inositol oxygenase; PDBTitle: crystal structure of mouse myo-inositol oxygenase in complex with2 substrate 48 d1f0ja_ not modelled 58.5 18 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 49 c2o8hA_ not modelled 57.3 14 PDB header:hydrolase Chain: A: PDB Molecule:phosphodiesterase-10a; PDBTitle: crystal structure of the catalytic domain of rat2 phosphodiesterase 10a 50 d2h44a1 not modelled 55.5 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 51 c3qi4A_ not modelled 54.8 12 PDB header:hydrolase Chain: A: PDB Molecule:high affinity cgmp-specific 3',5'-cyclic phosphodiesterase PDBTitle: crystal structure of pde9a(q453e) in complex with ibmx 52 c3ibjB_ not modelled 53.2 13 PDB header:hydrolase Chain: B: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase; PDBTitle: x-ray structure of pde2a 53 d2ibna1 not modelled 51.9 28 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:MioX-like 54 c2ounA_ not modelled 51.2 12 PDB header:hydrolase Chain: A: PDB Molecule:camp and camp-inhibited cgmp 3',5'-cyclic PDBTitle: crystal structure of pde10a2 in complex with amp 55 c2floA_ not modelled 49.0 9 PDB header:hydrolase Chain: A: PDB Molecule:exopolyphosphatase; PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7 56 c1z1lA_ not modelled 48.7 14 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase; PDBTitle: the crystal structure of the phosphodiesterase 2a catalytic2 domain 57 c2k0nA_ not modelled 37.7 22 PDB header:transcription Chain: A: PDB Molecule:mediator of rna polymerase ii transcription PDBTitle: solution structure of yeast gal11p kix domain 58 c3rv0C_ not modelled 30.1 36 PDB header:rna binding protein Chain: C: PDB Molecule:k. polysporus dcr1; PDBTitle: crystal structure of k. polysporus dcr1 without the c-terminal dsrbd 59 d1so2a_ not modelled 16.9 16 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 60 c3g3nA_ not modelled 15.2 12 PDB header:hydrolase Chain: A: PDB Molecule:high affinity camp-specific 3',5'-cyclic PDBTitle: pde7a catalytic domain in complex with 3-(2,6-2 difluorophenyl)-2-(methylthio)quinazolin-4(3h)-one 61 d1tbfa_ not modelled 14.3 12 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 62 c3r84O_ not modelled 13.8 19 PDB header:transcription Chain: O: PDB Molecule:mediator of rna polymerase ii transcription subunit 11; PDBTitle: structure of the mediator head subcomplex med11/22 63 d2dlda1 not modelled 12.9 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 64 c3bjcA_ not modelled 12.2 11 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: crystal structure of the pde5a catalytic domain in complex2 with a novel inhibitor 65 c2wukD_ not modelled 12.0 10 PDB header:cell cycle Chain: D: PDB Molecule:septum site-determining protein diviva; PDBTitle: diviva n-terminal domain, f17a mutant 66 d1j4aa1 not modelled 11.6 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Formate/glycerate dehydrogenases, NAD-domain 67 c3hi0B_ not modelled 11.2 13 PDB header:hydrolase Chain: B: PDB Molecule:putative exopolyphosphatase; PDBTitle: crystal structure of putative exopolyphosphatase (17739545) from2 agrobacterium tumefaciens str. c58 (dupont) at 2.30 a resolution 68 d1ygya2 not modelled 10.0 16 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 69 c3ecmA_ not modelled 9.1 11 PDB header:hydrolase Chain: A: PDB Molecule:high affinity camp-specific and ibmx-insensitive PDBTitle: crystal structure of the unliganded pde8a catalytic domain 70 d1odfa_ not modelled 8.9 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 71 d1dxya2 not modelled 8.3 11 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 72 c1z65A_ not modelled 7.7 17 PDB header:unknown function Chain: A: PDB Molecule:prion-like protein doppel; PDBTitle: mouse doppel 1-30 peptide 73 c3rv1B_ not modelled 6.7 38 PDB header:rna binding protein Chain: B: PDB Molecule:k. polysporus dcr1; PDBTitle: crystal structure of the n-terminal and rnase iii domains of k.2 polysporus dcr1 e224q mutant 74 c2k4vA_ not modelled 5.9 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pa1076; PDBTitle: solution structure of uncharacterized protein pa1076 from2 pseudomonas aeruginosa. northeast structural genomics3 consortium (nesg) target pat3, ontario center for4 structural proteomics target pa1076 . 75 d1sc6a2 not modelled 5.8 13 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 76 c1zklA_ not modelled 5.6 12 PDB header:hydrolase Chain: A: PDB Molecule:high-affinity camp-specific 3',5'-cyclic PDBTitle: multiple determinants for inhibitor selectivity of cyclic2 nucleotide phosphodiesterases 77 d1mvfd_ not modelled 5.6 21 Fold:Double-split beta-barrel Superfamily:AbrB/MazE/MraZ-like Family:Kis/PemI addiction antidote 78 c2wdfA_ not modelled 5.3 27 PDB header:hydrolase Chain: A: PDB Molecule:sulfur oxidation protein soxb; PDBTitle: termus thermophilus sulfate thiohydrolase soxb