Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	I	R	I	I	P	Q	D	E	L	G	S	S	E	K	R	T	A	D	M	I	P	P	L	L	F	P	R	L	K	N	L	Y	N	R	R	A	E	R	L	R	E	L	A	E	N	N	P	L	G	D	Y	L	R	F	A	A	L	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																									?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	H	A	Q	E	V	V	L	Y	D	H	P	L	E	M	D	L	T	A	R	I	K	E	A	S	A	Q	G	K	P	P	L	D	I	H	V	L	P	R	D	K	H	W	Q	K	L	L	M	A	L	I	A	E	L	K	P	E	M	S	G
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?	?	?	?	?	?													?	?	?	?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	A	L	A	V	I	E	N	L	E	K	A	S	T	Q	E	L	E	D	M	A	S	A	L	F	A	S	D	F	S	S	V	S	S	D	K	A	P	F	I	W	A	A	L	S	L	Y	W	A	Q	M	A	N	L	I	P	G	K	A	R
Secondary structure
SS confidence
Disorder												?	?																																										?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	E	Y	G	E	Q	R	Q	Y	C	P	V	C	G	S	M	P	V	S	S	M	V	Q	I	G	T	T	Q	G	L	R	Y	L	H	C	N	L	C	E	T	E	W	H	V	V	R	V	K	C	S	N	C	E	Q	S	G	K	L	H	Y
Secondary structure
SS confidence
Disorder		?	?	?	?																			?	?																															?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		W	S	L	D	D	E	Q	A	A	I	K	A	E	S	C	D	D	C	D	T	Y	L	K	I	L	Y	Q	E	K	D	P	K	I	E	A	V	A	D	D	L	A	S	L	V	L	D	A	R	M	E	Q	E	G	Y	A	R	S	S	I	N
Secondary structure
SS confidence
Disorder																																																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.
Sequence		P	F	L	F	P	G	E	G	E
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fiy chain A domain 1 Region: 23 - 307 Aligned: 280 Modelled: 285 Confidence: 100.0% Identity: 40% Fold: FdhE-like Superfamily: FdhE-like Family: FdhE-like Phyre2 PDB 1i3q chain I Region: 189 - 263 Aligned: 72 Modelled: 75 Confidence: 96.9% Identity: 15% PDB header:transcription Chain: I: PDB Molecule:dna-directed rna polymerase ii 14.2kd PDBTitle: rna polymerase ii crystal form i at 3.1 a resolution Phyre2 PDB 3h0g chain I Region: 189 - 263 Aligned: 71 Modelled: 75 Confidence: 96.6% Identity: 20% PDB header:transcription Chain: I: PDB Molecule:dna-directed rna polymerase ii subunit rpb9; PDBTitle: rna polymerase ii from schizosaccharomyces pombe Phyre2 PDB 3cng chain C Region: 189 - 222 Aligned: 31 Modelled: 34 Confidence: 92.4% Identity: 26% PDB header:hydrolase Chain: C: PDB Molecule:nudix hydrolase; PDBTitle: crystal structure of nudix hydrolase from nitrosomonas europaea Phyre2 PDB 2gb5 chain B Region: 186 - 227 Aligned: 34 Modelled: 42 Confidence: 92.4% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:nadh pyrophosphatase; PDBTitle: crystal structure of nadh pyrophosphatase (ec 3.6.1.22) (1790429) from2 escherichia coli k12 at 2.30 a resolution Phyre2 PDB 3a44 chain D Region: 212 - 248 Aligned: 37 Modelled: 37 Confidence: 91.7% Identity: 27% PDB header:metal binding protein Chain: D: PDB Molecule:hydrogenase nickel incorporation protein hypa; PDBTitle: crystal structure of hypa in the dimeric form Phyre2 PDB 1tfi chain A Region: 190 - 224 Aligned: 35 Modelled: 35 Confidence: 91.2% Identity: 17% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 1y1y chain S Region: 190 - 224 Aligned: 35 Modelled: 35 Confidence: 90.2% Identity: 20% PDB header:transferase/transcription/dna-rna hybrid Chain: S: PDB Molecule:transcription elongation factor s-ii; PDBTitle: rna polymerase ii-tfiis-dna/rna complex Phyre2 PDB 1qyp chain A Region: 227 - 266 Aligned: 40 Modelled: 40 Confidence: 89.6% Identity: 10% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 2gnr chain A domain 1 Region: 207 - 254 Aligned: 47 Modelled: 48 Confidence: 89.0% Identity: 15% Fold: OB-fold Superfamily: Nucleic acid-binding proteins Family: SSO2064-like Phyre2 PDB 1dl6 chain A Region: 225 - 262 Aligned: 31 Modelled: 38 Confidence: 88.9% Identity: 23% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 1pqv chain S Region: 190 - 224 Aligned: 35 Modelled: 35 Confidence: 88.7% Identity: 20% PDB header:transferase/transcription Chain: S: PDB Molecule:transcription elongation factor s-ii; PDBTitle: rna polymerase ii-tfiis complex Phyre2 PDB 2kdx chain A Region: 212 - 236 Aligned: 25 Modelled: 25 Confidence: 88.2% Identity: 20% PDB header:metal-binding protein Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein PDBTitle: solution structure of hypa protein Phyre2 PDB 1x6m chain A Region: 187 - 302 Aligned: 101 Modelled: 116 Confidence: 87.8% Identity: 21% Fold: Mss4-like Superfamily: Mss4-like Family: Glutathione-dependent formaldehyde-activating enzyme, Gfa Phyre2 PDB 2ztg chain A Region: 224 - 309 Aligned: 74 Modelled: 86 Confidence: 87.5% Identity: 28% PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus alanyl-trna2 synthetase lacking the c-terminal dimerization domain in3 complex with ala-sa Phyre2 PDB 3ndj chain A Region: 190 - 222 Aligned: 33 Modelled: 33 Confidence: 86.8% Identity: 27% PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: x-ray structure of a c-3'-methyltransferase in complex with s-2 adenosyl-l-homocysteine and sugar product Phyre2 PDB 1nui chain A Region: 187 - 220 Aligned: 28 Modelled: 34 Confidence: 86.7% Identity: 32% PDB header:replication Chain: A: PDB Molecule:dna primase/helicase; PDBTitle: crystal structure of the primase fragment of bacteriophage t7 primase-2 helicase protein Phyre2 PDB 1twf chain I domain 2 Region: 227 - 263 Aligned: 37 Modelled: 37 Confidence: 84.9% Identity: 14% Fold: Rubredoxin-like Superfamily: Zinc beta-ribbon Family: Transcriptional factor domain Phyre2 PDB 1hk8 chain A Region: 214 - 244 Aligned: 31 Modelled: 31 Confidence: 84.5% Identity: 16% Fold: PFL-like glycyl radical enzymes Superfamily: PFL-like glycyl radical enzymes Family: Class III anaerobic ribonucleotide reductase NRDD subunit Phyre2 PDB 1hk8 chain A Region: 214 - 244 Aligned: 31 Modelled: 31 Confidence: 84.5% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:anaerobic ribonucleotide-triphosphate reductase; PDBTitle: structural basis for allosteric substrate specificity2 regulation in class iii ribonucleotide reductases:3 nrdd in complex with dgtp Phyre2 1 d2fiya1 2 c1i3qI_ 3 c3h0gI_ 4 c3cngC_ 5 c2gb5B_ 6 c3a44D_ 7 d1tfia_ 8 c1y1yS_ 9 d1qypa_ 10 d2gnra1 11 d1dl6a_ 12 c1pqvS_ 13 c2kdxA_ 14 d1x6ma_ 15 c2ztgA_ 16 c3ndjA_ 17 c1nuiA_ 18 d1twfi2 19 d1hk8a_ 20 c1hk8A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2fiya1 100.0 40 Fold:FdhE-like Superfamily:FdhE-like Family:FdhE-like 2 c1i3qI_ 96.9 15 PDB header:transcription Chain: I: PDB Molecule:dna-directed rna polymerase ii 14.2kd PDBTitle: rna polymerase ii crystal form i at 3.1 a resolution 3 c3h0gI_ 96.6 20 PDB header:transcription Chain: I: PDB Molecule:dna-directed rna polymerase ii subunit rpb9; PDBTitle: rna polymerase ii from schizosaccharomyces pombe 4 c3cngC_ 92.4 26 PDB header:hydrolase Chain: C: PDB Molecule:nudix hydrolase; PDBTitle: crystal structure of nudix hydrolase from nitrosomonas europaea 5 c2gb5B_ 92.4 21 PDB header:hydrolase Chain: B: PDB Molecule:nadh pyrophosphatase; PDBTitle: crystal structure of nadh pyrophosphatase (ec 3.6.1.22) (1790429) from2 escherichia coli k12 at 2.30 a resolution 6 c3a44D_ 91.7 27 PDB header:metal binding protein Chain: D: PDB Molecule:hydrogenase nickel incorporation protein hypa; PDBTitle: crystal structure of hypa in the dimeric form 7 d1tfia_ 91.2 17 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 8 c1y1yS_ 90.2 20 PDB header:transferase/transcription/dna-rna hybrid Chain: S: PDB Molecule:transcription elongation factor s-ii; PDBTitle: rna polymerase ii-tfiis-dna/rna complex 9 d1qypa_ 89.6 10 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 10 d2gnra1 89.0 15 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:SSO2064-like 11 d1dl6a_ 88.9 23 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 12 c1pqvS_ 88.7 20 PDB header:transferase/transcription Chain: S: PDB Molecule:transcription elongation factor s-ii; PDBTitle: rna polymerase ii-tfiis complex 13 c2kdxA_ 88.2 20 PDB header:metal-binding protein Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein PDBTitle: solution structure of hypa protein 14 d1x6ma_ 87.8 21 Fold:Mss4-like Superfamily:Mss4-like Family:Glutathione-dependent formaldehyde-activating enzyme, Gfa 15 c2ztgA_ 87.5 28 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus alanyl-trna2 synthetase lacking the c-terminal dimerization domain in3 complex with ala-sa 16 c3ndjA_ 86.8 27 PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: x-ray structure of a c-3'-methyltransferase in complex with s-2 adenosyl-l-homocysteine and sugar product 17 c1nuiA_ 86.7 32 PDB header:replication Chain: A: PDB Molecule:dna primase/helicase; PDBTitle: crystal structure of the primase fragment of bacteriophage t7 primase-2 helicase protein 18 d1twfi2 84.9 14 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 19 d1hk8a_ 84.5 16 Fold:PFL-like glycyl radical enzymes Superfamily:PFL-like glycyl radical enzymes Family:Class III anaerobic ribonucleotide reductase NRDD subunit 20 c1hk8A_ 84.5 16 PDB header:oxidoreductase Chain: A: PDB Molecule:anaerobic ribonucleotide-triphosphate reductase; PDBTitle: structural basis for allosteric substrate specificity2 regulation in class iii ribonucleotide reductases:3 nrdd in complex with dgtp 21 c3k7aM_ not modelled 83.9 13 PDB header:transcription Chain: M: PDB Molecule:transcription initiation factor iib; PDBTitle: crystal structure of an rna polymerase ii-tfiib complex 22 c2opfA_ not modelled 83.6 20 PDB header:hydrolase/dna Chain: A: PDB Molecule:endonuclease viii; PDBTitle: crystal structure of the dna repair enzyme endonuclease-viii (nei)2 from e. coli (r252a) in complex with ap-site containing dna substrate 23 c3gn5B_ not modelled 81.8 25 PDB header:dna binding protein Chain: B: PDB Molecule:hth-type transcriptional regulator mqsa (ygit/b3021); PDBTitle: structure of the e. coli protein mqsa (ygit/b3021) 24 c2aklA_ not modelled 80.8 38 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:phna-like protein pa0128; PDBTitle: solution structure for phn-a like protein pa0128 from2 pseudomonas aeruginosa 25 c2lcqA_ not modelled 80.6 17 PDB header:metal binding protein Chain: A: PDB Molecule:putative toxin vapc6; PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii 26 c2odxA_ not modelled 80.4 17 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase polypeptide iv; PDBTitle: solution structure of zn(ii)cox4 27 d1wfka_ not modelled 80.2 22 Fold:FYVE/PHD zinc finger Superfamily:FYVE/PHD zinc finger Family:FYVE, a phosphatidylinositol-3-phosphate binding domain 28 c3eswA_ not modelled 80.0 15 PDB header:hydrolase Chain: A: PDB Molecule:peptide-n(4)-(n-acetyl-beta-glucosaminyl)asparagine PDBTitle: complex of yeast pngase with glcnac2-iac. 29 d1wiia_ not modelled 79.7 17 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Putative zinc binding domain 30 d2akla2 not modelled 79.6 35 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:PhnA zinc-binding domain 31 d1x3za1 not modelled 79.2 15 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Transglutaminase core 32 c2y69S_ not modelled 78.7 20 PDB header:electron transport Chain: S: PDB Molecule:cytochrome c oxidase subunit 5b; PDBTitle: bovine heart cytochrome c oxidase re-refined with molecular2 oxygen 33 c2js4A_ not modelled 78.0 31 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0434 protein bb2007; PDBTitle: solution nmr structure of bordetella bronchiseptica protein2 bb2007. northeast structural genomics consortium target3 bor54 34 d2f9yb1 not modelled 76.2 26 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 35 c2f9yB_ not modelled 76.2 26 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl transferase subunit PDBTitle: the crystal structure of the carboxyltransferase subunit of acc from2 escherichia coli 36 c2jr6A_ not modelled 75.9 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0434 protein nma0874; PDBTitle: solution structure of upf0434 protein nma0874. northeast structural2 genomics target mr32 37 c2zzfA_ not modelled 75.6 27 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of alanyl-trna synthetase without2 oligomerization domain 38 d1v54f_ not modelled 75.4 20 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Cytochrome c oxidase Subunit F 39 c1neeA_ not modelled 75.3 21 PDB header:translation Chain: A: PDB Molecule:probable translation initiation factor 2 beta PDBTitle: structure of archaeal translation factor aif2beta from2 methanobacterium thermoautrophicum 40 d1k81a_ not modelled 75.2 20 Fold:Zinc-binding domain of translation initiation factor 2 beta Superfamily:Zinc-binding domain of translation initiation factor 2 beta Family:Zinc-binding domain of translation initiation factor 2 beta 41 c2vjfB_ not modelled 74.9 22 PDB header:ligase Chain: B: PDB Molecule:mdm4 protein; PDBTitle: crystal structure of the mdm2-mdmx ring domain heterodimer 42 c2kyuA_ not modelled 74.6 19 PDB header:transferase Chain: A: PDB Molecule:histone-lysine n-methyltransferase mll; PDBTitle: the solution structure of the phd3 finger of mll 43 c2f9iD_ not modelled 74.5 23 PDB header:transferase Chain: D: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl PDBTitle: crystal structure of the carboxyltransferase subunit of acc2 from staphylococcus aureus 44 d1pfta_ not modelled 74.3 31 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 45 c3fl2A_ not modelled 73.1 18 PDB header:ligase Chain: A: PDB Molecule:e3 ubiquitin-protein ligase uhrf1; PDBTitle: crystal structure of the ring domain of the e3 ubiquitin-2 protein ligase uhrf1 46 d1ywsa1 not modelled 73.0 15 Fold:Rubredoxin-like Superfamily:CSL zinc finger Family:CSL zinc finger 47 c2dcuB_ not modelled 72.7 33 PDB header:translation Chain: B: PDB Molecule:translation initiation factor 2 beta subunit; PDBTitle: crystal structure of translation initiation factor aif2betagamma2 heterodimer with gdp 48 c3pihA_ not modelled 72.3 16 PDB header:hydrolase/dna Chain: A: PDB Molecule:uvrabc system protein a; PDBTitle: t. maritima uvra in complex with fluorescein-modified dna 49 d1nuia2 not modelled 71.5 38 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:DNA primase zinc finger 50 c1z6uA_ not modelled 71.2 14 PDB header:ligase Chain: A: PDB Molecule:np95-like ring finger protein isoform b; PDBTitle: np95-like ring finger protein isoform b [homo sapiens] 51 c3eb6A_ not modelled 70.7 26 PDB header:apoptosis, ligase Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 3; PDBTitle: structure of the ciap2 ring domain bound to ubch5b 52 c3nw0A_ not modelled 70.3 15 PDB header:metal binding protein Chain: A: PDB Molecule:non-structural maintenance of chromosomes element 1 PDBTitle: crystal structure of mageg1 and nse1 complex 53 d1chca_ not modelled 70.3 18 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 54 c2y43B_ not modelled 70.2 19 PDB header:ligase Chain: B: PDB Molecule:e3 ubiquitin-protein ligase rad18; PDBTitle: rad18 ubiquitin ligase ring domain structure 55 d1yuja_ not modelled 70.2 38 Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2 56 c2cklA_ not modelled 70.1 21 PDB header:transcription Chain: A: PDB Molecule:polycomb group ring finger protein 4; PDBTitle: ring1b-bmi1 e3 catalytic domain structure 57 c2e9hA_ not modelled 69.9 16 PDB header:translation Chain: A: PDB Molecule:eukaryotic translation initiation factor 5; PDBTitle: solution structure of the eif-5_eif-2b domain from human2 eukaryotic translation initiation factor 5 58 c1nnjA_ not modelled 69.7 28 PDB header:hydrolase Chain: A: PDB Molecule:formamidopyrimidine-dna glycosylase; PDBTitle: crystal structure complex between the lactococcus lactis fpg and an2 abasic site containing dna 59 d1wgea1 not modelled 68.7 24 Fold:Rubredoxin-like Superfamily:CSL zinc finger Family:CSL zinc finger 60 c2x5cB_ not modelled 68.7 38 PDB header:viral protein Chain: B: PDB Molecule:hypothetical protein orf131; PDBTitle: crystal structure of hypothetical protein orf131 from2 pyrobaculum spherical virus 61 c2d8tA_ not modelled 68.4 22 PDB header:metal binding protein Chain: A: PDB Molecule:ring finger protein 146; PDBTitle: solution structure of the ring domain of the human ring2 finger protein 146 62 c1ee8A_ not modelled 67.9 33 PDB header:dna binding protein Chain: A: PDB Molecule:mutm (fpg) protein; PDBTitle: crystal structure of mutm (fpg) protein from thermus thermophilus hb8 63 c3k35D_ not modelled 67.5 15 PDB header:hydrolase Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: crystal structure of human sirt6 64 d1pfva3 not modelled 67.1 20 Fold:Rubredoxin-like Superfamily:Methionyl-tRNA synthetase (MetRS), Zn-domain Family:Methionyl-tRNA synthetase (MetRS), Zn-domain 65 d2cona1 not modelled 67.1 17 Fold:Rubredoxin-like Superfamily:NOB1 zinc finger-like Family:NOB1 zinc finger-like 66 c3zyqA_ not modelled 66.8 16 PDB header:signaling Chain: A: PDB Molecule:hepatocyte growth factor-regulated tyrosine kinase PDBTitle: crystal structure of the tandem vhs and fyve domains of hepatocyte2 growth factor-regulated tyrosine kinase substrate (hgs-hrs) at 1.483 a resolution 67 c2csyA_ not modelled 66.6 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:zinc finger protein 183-like 1; PDBTitle: solution structure of the ring domain of the zinc finger2 protein 183-like 1 68 d1p91a_ not modelled 66.2 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:rRNA methyltransferase RlmA 69 d2pk7a1 not modelled 66.2 17 Fold:Trm112p-like Superfamily:Trm112p-like Family:Trm112p-like 70 c2qkdA_ not modelled 65.9 18 PDB header:signaling protein, cell cycle Chain: A: PDB Molecule:zinc finger protein zpr1; PDBTitle: crystal structure of tandem zpr1 domains 71 c2owoA_ not modelled 65.5 38 PDB header:ligase/dna Chain: A: PDB Molecule:dna ligase; PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate 72 c1yuzB_ not modelled 65.5 18 PDB header:oxidoreductase Chain: B: PDB Molecule:nigerythrin; PDBTitle: partially reduced state of nigerythrin 73 c2jrpA_ not modelled 64.5 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative cytoplasmic protein; PDBTitle: solution nmr structure of yfgj from salmonella typhimurium2 modeled with two zn+2 bound, northeast structural genomics3 consortium target str86 74 d2ct7a1 not modelled 64.4 15 Fold:RING/U-box Superfamily:RING/U-box Family:IBR domain 75 d2dkta1 not modelled 64.3 21 Fold:CHY zinc finger-like Superfamily:CHY zinc finger-like Family:CHY zinc finger 76 d1dgsa1 not modelled 64.1 50 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3 77 c2f5qA_ not modelled 63.8 31 PDB header:hydrolase/dna Chain: A: PDB Molecule:formamidopyrimidine-dna glycosidase; PDBTitle: catalytically inactive (e3q) mutm crosslinked to oxog:c2 containing dna cc2 78 c2yhoE_ not modelled 63.7 23 PDB header:ligase Chain: E: PDB Molecule:e3 ubiquitin-protein ligase mylip; PDBTitle: the idol-ube2d complex mediates sterol-dependent degradation of the2 ldl receptor 79 d1e7la2 not modelled 63.6 29 Fold:His-Me finger endonucleases Superfamily:His-Me finger endonucleases Family:Recombination endonuclease VII, N-terminal domain 80 c2hjhB_ not modelled 63.3 16 PDB header:hydrolase Chain: B: PDB Molecule:nad-dependent histone deacetylase sir2; PDBTitle: crystal structure of the sir2 deacetylase 81 d1q1aa_ not modelled 62.6 26 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 82 d1k3xa3 not modelled 62.2 23 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 83 d2baya1 not modelled 62.2 9 Fold:RING/U-box Superfamily:RING/U-box Family:U-box 84 c1z2qA_ not modelled 61.9 24 PDB header:membrane protein Chain: A: PDB Molecule:lm5-1; PDBTitle: high-resolution solution structure of the lm5-1 fyve domain2 from leishmania major 85 c3hi2C_ not modelled 61.5 30 PDB header:dna binding protein/toxin Chain: C: PDB Molecule:hth-type transcriptional regulator mqsa(ygit); PDBTitle: structure of the n-terminal domain of the e. coli antitoxin mqsa2 (ygit/b3021) in complex with the e. coli toxin mqsr (ygiu/b3022) 86 c1fbvA_ not modelled 61.4 28 PDB header:ligase Chain: A: PDB Molecule:signal transduction protein cbl; PDBTitle: structure of a cbl-ubch7 complex: ring domain function in2 ubiquitin-protein ligases 87 d1bora_ not modelled 61.3 20 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 88 c2cttA_ not modelled 61.1 25 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily a member 3; PDBTitle: solution structure of zinc finger domain from human dnaj2 subfamily a menber 3 89 c2gajA_ not modelled 60.9 38 PDB header:isomerase Chain: A: PDB Molecule:dna topoisomerase i; PDBTitle: structure of full length topoisomerase i from thermotoga maritima in2 monoclinic crystal form 90 c2jmdA_ not modelled 60.7 14 PDB header:ligase Chain: A: PDB Molecule:tnf receptor-associated factor 6; PDBTitle: solution structure of the ring domain of human traf6 91 c2kpiA_ not modelled 60.5 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein sco3027; PDBTitle: solution nmr structure of streptomyces coelicolor sco30272 modeled with zn+2 bound, northeast structural genomics3 consortium target rr58 92 c1k82D_ not modelled 60.2 28 PDB header:hydrolase/dna Chain: D: PDB Molecule:formamidopyrimidine-dna glycosylase; PDBTitle: crystal structure of e.coli formamidopyrimidine-dna2 glycosylase (fpg) covalently trapped with dna 93 d1ee8a3 not modelled 60.1 33 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 94 c2qnfB_ not modelled 60.1 26 PDB header:hydrolase/dna Chain: B: PDB Molecule:recombination endonuclease vii; PDBTitle: crystal structure of t4 endonuclease vii h43n mutant in2 complex with heteroduplex dna containing base mismatches 95 c1nltA_ not modelled 60.0 21 PDB header:protein transport Chain: A: PDB Molecule:mitochondrial protein import protein mas5; PDBTitle: the crystal structure of hsp40 ydj1 96 d2ds5a1 not modelled 59.2 25 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:ClpX chaperone zinc binding domain 97 c3glsC_ not modelled 58.6 24 PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3 98 c2eciA_ not modelled 58.5 19 PDB header:metal binding protein Chain: A: PDB Molecule:tnf receptor-associated factor 6; PDBTitle: solution structure of the ring domain of the human tnf2 receptor-associated factor 6 protein 99 c3pkiF_ not modelled 58.4 15 PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose 100 d1yc5a1 not modelled 58.4 29 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 101 c2ectA_ not modelled 58.2 18 PDB header:metal binding protein Chain: A: PDB Molecule:ring finger protein 126; PDBTitle: solution structure of the zinc finger, c3hc4 type (ring2 finger) domain of ring finger protein 126 102 d1jm7a_ not modelled 58.2 18 Fold:RING/U-box Superfamily:RING/U-box Family:RING finger domain, C3HC4 103 d1l1ta3 not modelled 58.1 29 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 104 c1ovxB_ not modelled 57.9 25 PDB header:metal binding protein Chain: B: PDB Molecule:atp-dependent clp protease atp-binding subunit clpx; PDBTitle: nmr structure of the e. coli clpx chaperone zinc binding domain dimer 105 c3cw2M_ not modelled 57.6 21 PDB header:translation Chain: M: PDB Molecule:translation initiation factor 2 subunit beta; PDBTitle: crystal structure of the intact archaeal translation2 initiation factor 2 from sulfolobus solfataricus . 106 d1yuza2 not modelled 56.6 14 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 107 d1exka_ not modelled 56.4 23 Fold:DnaJ/Hsp40 cysteine-rich domain Superfamily:DnaJ/Hsp40 cysteine-rich domain Family:DnaJ/Hsp40 cysteine-rich domain 108 d1wgma_ not modelled 56.4 7 Fold:RING/U-box Superfamily:RING/U-box Family:U-box 109 d1m2ka_ not modelled 56.2 30 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 110 c2f42A_ not modelled 56.2 7 PDB header:chaperone Chain: A: PDB Molecule:stip1 homology and u-box containing protein 1; PDBTitle: dimerization and u-box domains of zebrafish c-terminal of hsp702 interacting protein 111 c2ea5A_ not modelled 56.1 23 PDB header:cell cycle Chain: A: PDB Molecule:cell growth regulator with ring finger domain PDBTitle: solution structure of the ring domain of the human cell2 growth regulator with ring finger domain 1 protein 112 c2kwqA_ not modelled 55.9 23 PDB header:dna binding protein Chain: A: PDB Molecule:protein mcm10 homolog; PDBTitle: mcm10 c-terminal dna binding domain 113 c2cklB_ not modelled 55.7 26 PDB header:transcription Chain: B: PDB Molecule:ubiquitin ligase protein ring2; PDBTitle: ring1b-bmi1 e3 catalytic domain structure 114 c3htkC_ not modelled 55.7 8 PDB header:recombination/replication/ligase Chain: C: PDB Molecule:e3 sumo-protein ligase mms21; PDBTitle: crystal structure of mms21 and smc5 complex 115 d1tdza3 not modelled 55.4 26 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 116 d1r2za3 not modelled 55.0 29 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:C-terminal, Zn-finger domain of MutM-like DNA repair proteins 117 d1vd4a_ not modelled 54.9 35 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 118 d1vs6z1 not modelled 54.7 11 Fold:L28p-like Superfamily:L28p-like Family:Ribosomal protein L31p 119 c1q14A_ not modelled 54.3 19 PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2 120 c2ecmA_ not modelled 54.1 24 PDB header:metal binding protein Chain: A: PDB Molecule:ring finger and chy zinc finger domain- PDBTitle: solution structure of the ring domain of the ring finger2 and chy zinc finger domain-containing protein 1 from mus3 musculus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0