Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	T	N	T	K	L	D	P	I	E	T	A	S	V	D	E	L	Q	A	L	Q	T	Q	R	L	K	W	T	L	K	H	A	Y	E	N	V	P	M	Y	R	R	K	F	D	A	A	G	V	H	P	D	D	F	R	E	L	S	D	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	K	F	P	C	T	T	K	Q	D	L	R	D	N	Y	P	F	D	T	F	A	V	P	M	E	Q	V	V	R	I	H	A	S	S	G	T	T	G	K	P	T	V	V	G	Y	T	Q	N	D	I	D	N	W	A	N	I	V	A	R	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	R	A	A	G	G	S	P	K	D	K	I	H	V	A	Y	G	Y	G	L	F	T	G	G	L	G	A	H	Y	G	A	E	R	L	G	A	T	V	I	P	M	S	G	G	Q	T	E	K	Q	A	Q	L	I	R	D	F	Q	P	D	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	M	V	T	P	S	Y	C	L	N	L	I	E	E	L	E	R	Q	L	G	G	D	A	S	G	C	S	L	R	V	G	V	F	G	A	E	P	W	T	Q	A	M	R	K	E	I	E	R	R	L	G	I	T	A	L	D	I	Y	G	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	E	V	M	G	P	G	V	A	M	E	C	L	E	T	T	D	G	P	T	I	W	E	D	H	F	Y	P	E	I	V	N	P	H	D	G	T	P	L	A	D	G	E	H	G	E	L	L	F	T	T	L	T	K	E	A	L	P	V	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	Y	R	T	R	D	L	T	R	L	L	P	G	T	A	R	T	M	R	R	M	D	R	I	S	G	R	S	D	D	M	L	I	I	R	G	V	N	V	F	P	S	Q	L	E	E	E	I	V	K	F	E	H	L	S	P	H	Y	Q	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		E	V	N	R	R	G	H	L	D	S	L	S	V	K	V	E	L	K	E	S	S	L	T	L	T	H	E	Q	R	C	Q	V	C	H	Q	L	R	H	R	I	K	S	M	V	G	I	S	T	D	V	M	I	V	N	C	G	S	I	P	R
Secondary structure
SS confidence
Disorder																					?	?	?	?	?																																?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.
Sequence		S	E	G	K	A	C	R	V	F	D	L	R	N	I	V	G	A
Secondary structure
SS confidence
Disorder		?											?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2y4o chain A Region: 7 - 433 Aligned: 426 Modelled: 427 Confidence: 100.0% Identity: 67% PDB header:ligase Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak2 in complex with phenylacetyl adenylate Phyre2 PDB 2y27 chain B Region: 7 - 432 Aligned: 424 Modelled: 419 Confidence: 100.0% Identity: 63% PDB header:ligase Chain: B: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak1 in complex with atp from2 burkholderia cenocepacia Phyre2 PDB 3qov chain D Region: 9 - 433 Aligned: 415 Modelled: 424 Confidence: 100.0% Identity: 41% PDB header:ligase Chain: D: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of a hypothetical acyl-coa ligase (bt_0428) from2 bacteroides thetaiotaomicron vpi-5482 at 2.20 a resolution Phyre2 PDB 1pg4 chain A Region: 73 - 435 Aligned: 348 Modelled: 363 Confidence: 100.0% Identity: 20% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 2vsq chain A Region: 73 - 427 Aligned: 329 Modelled: 349 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:surfactin synthetase subunit 3; PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module Phyre2 PDB 1ry2 chain A Region: 73 - 436 Aligned: 345 Modelled: 362 Confidence: 100.0% Identity: 19% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3hgu chain B Region: 23 - 315 Aligned: 286 Modelled: 293 Confidence: 100.0% Identity: 19% PDB header:biosynthetic protein Chain: B: PDB Molecule:ehpf; PDBTitle: structure of phenazine antibiotic biosynthesis protein Phyre2 PDB 3tsy chain A Region: 73 - 364 Aligned: 283 Modelled: 292 Confidence: 100.0% Identity: 17% PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein Phyre2 PDB 3cw9 chain A domain 1 Region: 76 - 436 Aligned: 346 Modelled: 361 Confidence: 100.0% Identity: 18% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3e7w chain A Region: 73 - 435 Aligned: 352 Modelled: 363 Confidence: 100.0% Identity: 12% PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains Phyre2 PDB 3gqw chain B Region: 76 - 434 Aligned: 343 Modelled: 359 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:fatty acid amp ligase; PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound Phyre2 PDB 1mdb chain A Region: 76 - 435 Aligned: 339 Modelled: 360 Confidence: 100.0% Identity: 16% Fold: Acetyl-CoA synthetase-like Superfamily: Acetyl-CoA synthetase-like Family: Acetyl-CoA synthetase-like Phyre2 PDB 3etc chain B Region: 75 - 420 Aligned: 329 Modelled: 346 Confidence: 100.0% Identity: 16% PDB header:ligase Chain: B: PDB Molecule:amp-binding protein; PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298 Phyre2 PDB 3ni2 chain A Region: 76 - 432 Aligned: 340 Modelled: 357 Confidence: 100.0% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:4-coumarate:coa ligase; PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase Phyre2 PDB 3kxw chain A Region: 76 - 435 Aligned: 353 Modelled: 360 Confidence: 100.0% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:saframycin mx1 synthetase b; PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila Phyre2 PDB 3ite chain B Region: 76 - 433 Aligned: 334 Modelled: 358 Confidence: 100.0% Identity: 15% PDB header:ligase Chain: B: PDB Molecule:sidn siderophore synthetase; PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase Phyre2 PDB 3eyn chain B Region: 90 - 434 Aligned: 328 Modelled: 342 Confidence: 100.0% Identity: 15% PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Phyre2 PDB 3nyr chain A Region: 76 - 420 Aligned: 327 Modelled: 342 Confidence: 100.0% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:malonyl-coa ligase; PDBTitle: malonyl-coa ligase ternary product complex with malonyl-coa and amp2 bound Phyre2 PDB 2d1t chain A Region: 81 - 435 Aligned: 338 Modelled: 352 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:luciferin 4-monooxygenase; PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue Phyre2 PDB 2v7b chain B Region: 78 - 433 Aligned: 334 Modelled: 356 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:benzoate-coenzyme a ligase; PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400 Phyre2 1 c2y4oA_ 2 c2y27B_ 3 c3qovD_ 4 d1pg4a_ 5 c2vsqA_ 6 d1ry2a_ 7 c3hguB_ 8 c3tsyA_ 9 d3cw9a1 10 c3e7wA_ 11 c3gqwB_ 12 d1mdba_ 13 c3etcB_ 14 c3ni2A_ 15 c3kxwA_ 16 c3iteB_ 17 c3eynB_ 18 c3nyrA_ 19 c2d1tA_ 20 c2v7bB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2y4oA_ 100.0 67 PDB header:ligase Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak2 in complex with phenylacetyl adenylate 2 c2y27B_ 100.0 63 PDB header:ligase Chain: B: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of paak1 in complex with atp from2 burkholderia cenocepacia 3 c3qovD_ 100.0 41 PDB header:ligase Chain: D: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: crystal structure of a hypothetical acyl-coa ligase (bt_0428) from2 bacteroides thetaiotaomicron vpi-5482 at 2.20 a resolution 4 d1pg4a_ 100.0 20 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 5 c2vsqA_ 100.0 19 PDB header:ligase Chain: A: PDB Molecule:surfactin synthetase subunit 3; PDBTitle: structure of surfactin a synthetase c (srfa-c), a2 nonribosomal peptide synthetase termination module 6 d1ry2a_ 100.0 19 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 7 c3hguB_ 100.0 19 PDB header:biosynthetic protein Chain: B: PDB Molecule:ehpf; PDBTitle: structure of phenazine antibiotic biosynthesis protein 8 c3tsyA_ 100.0 17 PDB header:ligase, transferase Chain: A: PDB Molecule:fusion protein 4-coumarate--coa ligase 1, resveratrol PDBTitle: 4-coumaroyl-coa ligase::stilbene synthase fusion protein 9 d3cw9a1 100.0 18 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 10 c3e7wA_ 100.0 12 PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: crystal structure of dlta: implications for the reaction2 mechanism of non-ribosomal peptide synthetase (nrps)3 adenylation domains 11 c3gqwB_ 100.0 18 PDB header:ligase Chain: B: PDB Molecule:fatty acid amp ligase; PDBTitle: crystal structure of a fatty acid amp ligase from e. coli with an acyl2 adenylate product bound 12 d1mdba_ 100.0 16 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 13 c3etcB_ 100.0 16 PDB header:ligase Chain: B: PDB Molecule:amp-binding protein; PDBTitle: 2.1 a structure of acyl-adenylate synthetase from methanosarcina2 acetivorans containing a link between lys256 and cys298 14 c3ni2A_ 100.0 17 PDB header:ligase Chain: A: PDB Molecule:4-coumarate:coa ligase; PDBTitle: crystal structures and enzymatic mechanisms of a populus tomentosa 4-2 coumarate:coa ligase 15 c3kxwA_ 100.0 13 PDB header:ligase Chain: A: PDB Molecule:saframycin mx1 synthetase b; PDBTitle: the crystal structure of fatty acid amp ligase from legionella2 pneumophila 16 c3iteB_ 100.0 15 PDB header:ligase Chain: B: PDB Molecule:sidn siderophore synthetase; PDBTitle: the third adenylation domain of the fungal sidn non-2 ribosomal peptide synthetase 17 c3eynB_ 100.0 15 PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa 18 c3nyrA_ 100.0 13 PDB header:ligase Chain: A: PDB Molecule:malonyl-coa ligase; PDBTitle: malonyl-coa ligase ternary product complex with malonyl-coa and amp2 bound 19 c2d1tA_ 100.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:luciferin 4-monooxygenase; PDBTitle: crystal structure of the thermostable japanese firefly2 luciferase red-color emission s286n mutant complexed with3 high-energy intermediate analogue 20 c2v7bB_ 100.0 20 PDB header:ligase Chain: B: PDB Molecule:benzoate-coenzyme a ligase; PDBTitle: crystal structures of a benzoate coa ligase from2 burkholderia xenovorans lb400 21 c3iplB_ not modelled 100.0 19 PDB header:ligase Chain: B: PDB Molecule:2-succinylbenzoate--coa ligase; PDBTitle: crystal structure of o-succinylbenzoic acid-coa ligase from2 staphylococcus aureus subsp. aureus mu50 22 d1v25a_ not modelled 100.0 18 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 23 c3g7sA_ not modelled 100.0 19 PDB header:ligase Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1); PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus 24 c3dhvA_ not modelled 100.0 16 PDB header:ligase Chain: A: PDB Molecule:d-alanine-poly(phosphoribitol) ligase; PDBTitle: crystal structure of dlta protein in complex with d-alanine2 adenylate 25 d1lcia_ not modelled 100.0 13 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 26 c1amuB_ not modelled 100.0 15 PDB header:peptide synthetase Chain: B: PDB Molecule:gramicidin synthetase 1; PDBTitle: phenylalanine activating domain of gramicidin synthetase 12 in a complex with amp and phenylalanine 27 d1amua_ not modelled 100.0 16 Fold:Acetyl-CoA synthetase-like Superfamily:Acetyl-CoA synthetase-like Family:Acetyl-CoA synthetase-like 28 c3l8cA_ not modelled 100.0 17 PDB header:ligase Chain: A: PDB Molecule:d-alanine--poly(phosphoribitol) ligase subunit 1; PDBTitle: structure of probable d-alanine--poly(phosphoribitol) ligase2 subunit-1 from streptococcus pyogenes 29 c3o82B_ not modelled 99.9 18 PDB header:ligase Chain: B: PDB Molecule:peptide arylation enzyme; PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine 30 c3ivrA_ not modelled 99.9 13 PDB header:ligase Chain: A: PDB Molecule:putative long-chain-fatty-acid coa ligase; PDBTitle: crystal structure of putative long-chain-fatty-acid coa ligase from2 rhodopseudomonas palustris cga009 31 c3e53A_ not modelled 99.9 14 PDB header:ligase Chain: A: PDB Molecule:fatty-acid-coa ligase fadd28; PDBTitle: crystal structure of n-terminal domain of a fatty acyl amp2 ligase faal28 from mycobacterium tuberculosis 32 c3o82A_ not modelled 99.8 18 PDB header:ligase Chain: A: PDB Molecule:peptide arylation enzyme; PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine 33 c3laxA_ not modelled 99.6 28 PDB header:ligase Chain: A: PDB Molecule:phenylacetate-coenzyme a ligase; PDBTitle: the crystal structure of a domain of phenylacetate-coenzyme2 a ligase from bacteroides vulgatus atcc 8482 34 c2wh7A_ not modelled 34.7 44 PDB header:hydrolase Chain: A: PDB Molecule:hyaluronidase-phage associated; PDBTitle: the partial structure of a group a streptpcoccal phage-2 encoded tail fibre hyaluronate lyase hylp2 35 d1whua_ not modelled 34.0 27 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Family:Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 36 c2i2xD_ not modelled 29.9 11 PDB header:transferase Chain: D: PDB Molecule:methyltransferase 1; PDBTitle: crystal structure of methanol:cobalamin methyltransferase complex2 mtabc from methanosarcina barkeri 37 d3bula2 not modelled 29.2 11 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 38 d1hska2 not modelled 29.1 18 Fold:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain Superfamily:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain Family:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 39 d1pk1c1 not modelled 27.0 21 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 40 d1wwva1 not modelled 23.6 15 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 41 c2c3fA_ not modelled 19.1 44 PDB header:lyase Chain: A: PDB Molecule:hyaluronidase, phage associated; PDBTitle: the structure of a group a streptococcal phage-encoded2 tail-fibre showing hyaluronan lyase activity. 42 d2c3fa1 not modelled 19.1 44 Fold:Triple-stranded beta-helix Superfamily:Phage fibre proteins Family:HylP-like 43 c1bmtB_ not modelled 16.1 13 PDB header:methyltransferase Chain: B: PDB Molecule:methionine synthase; PDBTitle: how a protein binds b12: a 3.o angstrom x-ray structure of2 the b12-binding domains of methionine synthase 44 d1dpta_ not modelled 15.1 6 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MIF-related 45 c1pk1A_ not modelled 14.5 28 PDB header:transcription repression Chain: A: PDB Molecule:polyhomeotic-proximal chromatin protein; PDBTitle: hetero sam domain structure of ph and scm. 46 c2ormA_ not modelled 14.4 11 PDB header:isomerase Chain: A: PDB Molecule:probable tautomerase hp0924; PDBTitle: crystal structure of the 4-oxalocrotonate tautomerase homologue dmpi2 from helicobacter pylori. 47 d2o70a1 not modelled 13.8 13 Fold:UraD-like Superfamily:UraD-Like Family:UraD-like 48 c3ry0A_ not modelled 13.7 14 PDB header:isomerase Chain: A: PDB Molecule:putative tautomerase; PDBTitle: crystal structure of tomn, a 4-oxalocrotonate tautomerase homologue in2 tomaymycin biosynthetic pathway 49 d1bjpa_ not modelled 13.3 10 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:4-oxalocrotonate tautomerase-like 50 c3ezxA_ not modelled 12.5 12 PDB header:transferase Chain: A: PDB Molecule:monomethylamine corrinoid protein 1; PDBTitle: structure of methanosarcina barkeri monomethylamine2 corrinoid protein 51 d1otfa_ not modelled 12.5 16 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:4-oxalocrotonate tautomerase-like 52 c3kk1B_ not modelled 11.6 12 PDB header:transferase/dna Chain: B: PDB Molecule:reverse transcriptase p51 subunit; PDBTitle: hiv-1 reverse transcriptase-dna complex with nuceotide inhibitor gs-2 9148-diphosphate bound in nucleotide site 53 c3ebrA_ not modelled 11.5 19 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized rmlc-like cupin; PDBTitle: crystal structure of an rmlc-like cupin protein (reut_a0381) from2 ralstonia eutropha jmp134 at 2.60 a resolution 54 c1hskA_ not modelled 11.2 18 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvoylglucosamine reductase; PDBTitle: crystal structure of s. aureus murb 55 c3abfB_ not modelled 11.1 18 PDB header:isomerase Chain: B: PDB Molecule:4-oxalocrotonate tautomerase; PDBTitle: crystal structure of a 4-oxalocrotonate tautomerase homologue2 (tthb242) 56 c2op8A_ not modelled 11.0 22 PDB header:isomerase Chain: A: PDB Molecule:probable tautomerase ywhb; PDBTitle: crystal structure of ywhb- homologue of 4-oxalocrotonate tautomerase 57 c2x4kB_ not modelled 10.5 16 PDB header:isomerase Chain: B: PDB Molecule:4-oxalocrotonate tautomerase; PDBTitle: crystal structure of sar1376, a putative 4-oxalocrotonate2 tautomerase from the methicillin-resistant staphylococcus3 aureus (mrsa) 58 d1kw4a_ not modelled 10.2 22 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 59 d1iwga3 not modelled 10.0 8 Fold:Ferredoxin-like Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 60 d1h80a_ not modelled 10.0 31 Fold:Single-stranded right-handed beta-helix Superfamily:Pectin lyase-like Family:iota-carrageenase 61 d2zd1b1 not modelled 9.3 12 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Reverse transcriptase 62 c1rthA_ not modelled 8.6 12 PDB header:nucleotidyltransferase Chain: A: PDB Molecule:hiv-1 reverse transcriptase; PDBTitle: high resolution structures of hiv-1 rt from four rt-2 inhibitor complexes 63 d1ucra_ not modelled 8.3 57 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Dissimilatory sulfite reductase DsvD 64 d2qfia1 not modelled 8.3 13 Fold:Alpha-lytic protease prodomain-like Superfamily:Cation efflux protein cytoplasmic domain-like Family:Cation efflux protein cytoplasmic domain-like 65 c1y80A_ not modelled 8.1 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted cobalamin binding protein; PDBTitle: structure of a corrinoid (factor iiim)-binding protein from2 moorella thermoacetica 66 c1x4rA_ not modelled 7.9 71 PDB header:apoptosis Chain: A: PDB Molecule:parp14 protein; PDBTitle: solution structure of wwe domain in parp14 protein 67 c3mb2G_ not modelled 7.7 12 PDB header:isomerase Chain: G: PDB Molecule:4-oxalocrotonate tautomerase family enzyme - alpha subunit; PDBTitle: kinetic and structural characterization of a heterohexamer 4-2 oxalocrotonate tautomerase from chloroflexus aurantiacus j-10-fl:3 implications for functional and structural diversity in the4 tautomerase superfamily 68 c2pmzV_ not modelled 7.6 22 PDB header:translation, transferase Chain: V: PDB Molecule:dna-directed rna polymerase subunit h; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus 69 d2icwg1 not modelled 7.5 31 Fold:Superantigen MAM Superfamily:Superantigen MAM Family:Superantigen MAM 70 c2do9A_ not modelled 6.6 27 PDB header:signaling protein Chain: A: PDB Molecule:nacht-, lrr- and pyd-containing protein 10; PDBTitle: solution structure of the pyrin/paad-dapin domain in mouse2 nalp10 (nacht, leucine rich repeat and pyd containing 10) 71 c2pjkA_ not modelled 6.4 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:178aa long hypothetical molybdenum cofactor PDBTitle: structure of hypothetical molybdenum cofactor biosynthesis2 protein b from sulfolobus tokodaii 72 c2bcmB_ not modelled 6.2 43 PDB header:cell adhesion Chain: B: PDB Molecule:f1845 fimbrial protein; PDBTitle: daae adhesin 73 c2epbA_ not modelled 6.2 63 PDB header:transcription Chain: A: PDB Molecule:chromodomain-helicase-dna-binding protein 6; PDBTitle: solution structure of chromo domain 2 in chromodomain-2 helicase-dna-binding protein 6 74 d1uhra_ not modelled 6.2 36 Fold:SWIB/MDM2 domain Superfamily:SWIB/MDM2 domain Family:SWIB/MDM2 domain 75 c2qfiB_ not modelled 6.2 14 PDB header:transport protein Chain: B: PDB Molecule:ferrous-iron efflux pump fief; PDBTitle: structure of the zinc transporter yiip 76 c3idwA_ not modelled 6.1 18 PDB header:endocytosis Chain: A: PDB Molecule:actin cytoskeleton-regulatory complex protein sla1; PDBTitle: crystal structure of sla1 homology domain 2 77 d2edua1 not modelled 6.1 22 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:ComEA-like 78 d1mwwa_ not modelled 6.0 11 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:Hypothetical protein HI1388.1 79 c2zztA_ not modelled 6.0 8 PDB header:transport protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of the cytosolic domain of the cation2 diffusion facilitator family protein 80 c1pk1B_ not modelled 6.0 15 PDB header:transcription repression Chain: B: PDB Molecule:sex comb on midleg cg9495-pa; PDBTitle: hetero sam domain structure of ph and scm. 81 d2f3na1 not modelled 6.0 12 Fold:SAM domain-like Superfamily:SAM/Pointed domain Family:SAM (sterile alpha motif) domain 82 c1k98A_ not modelled 5.9 13 PDB header:transferase Chain: A: PDB Molecule:methionine synthase; PDBTitle: adomet complex of meth c-terminal fragment 83 d1gyxa_ not modelled 5.9 6 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:4-oxalocrotonate tautomerase-like 84 c2fvnA_ not modelled 5.8 36 PDB header:cell adhesion Chain: A: PDB Molecule:protein afad; PDBTitle: the fibrillar tip complex of the afa/dr adhesins from2 pathogen e. coli displays synergistic binding to 5 1 and v3 3 integrins 85 c3bs7A_ not modelled 5.6 15 PDB header:signaling protein Chain: A: PDB Molecule:protein aveugle; PDBTitle: crystal structure of the sterile alpha motif (sam) domain2 of hyphen/aveugle 86 d2aala1 not modelled 5.6 26 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:MSAD-like 87 c3bs5A_ not modelled 5.6 15 PDB header:signaling protein/membrane protein Chain: A: PDB Molecule:protein aveugle; PDBTitle: crystal structure of hcnk2-sam/dhyp-sam complex 88 c2dn5A_ not modelled 5.4 45 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-057, a gtf2i domain in human2 cdna 89 c3cmqA_ not modelled 5.1 10 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase, mitochondrial; PDBTitle: crystal structure of human mitochondrial phenylalanine trna2 synthetase 90 d1f06a2 not modelled 5.1 9 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:Dihydrodipicolinate reductase-like 91 d7reqa2 not modelled 5.0 14 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0