Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	K	Y	I	V	T	W	D	M	L	Q	I	H	A	R	K	L	A	S	R	L	M	P	S	E	Q	W	K	G	I	I	A	V	S	R	G	G	L	V	P	G	A	L	L	A	R	E	L	G	I	R	H	V	D	T	V	C	I
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	S	Y	D	H	D	N	Q	R	E	L	K	V	L	K	R	A	E	G	D	G	E	G	F	I	V	I	D	D	L	V	D	T	G	G	T	A	V	A	I	R	E	M	Y	P	K	A	H	F	V	T	I	F	A	K	P	A	G	R	P
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
Sequence		L	V	D	D	Y	V	V	D	I	P	Q	D	T	W	I	E	Q	P	W	D	M	G	V	V	F	V	P	P	I	S	G	R
Secondary structure
SS confidence
Disorder																											?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1nul chain A Region: 3 - 152 Aligned: 142 Modelled: 150 Confidence: 100.0% Identity: 99% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2jkz chain B Region: 3 - 141 Aligned: 138 Modelled: 139 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form) Phyre2 PDB 1vdm chain A domain 1 Region: 3 - 141 Aligned: 136 Modelled: 139 Confidence: 100.0% Identity: 26% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 3kb8 chain A Region: 3 - 150 Aligned: 147 Modelled: 148 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp Phyre2 PDB 1fsg chain A Region: 3 - 150 Aligned: 147 Modelled: 148 Confidence: 100.0% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1p17 chain B Region: 1 - 150 Aligned: 149 Modelled: 150 Confidence: 100.0% Identity: 24% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1pzm chain A Region: 1 - 150 Aligned: 145 Modelled: 150 Confidence: 100.0% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1tc1 chain A Region: 1 - 150 Aligned: 149 Modelled: 150 Confidence: 100.0% Identity: 23% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1cjb chain A Region: 3 - 150 Aligned: 148 Modelled: 148 Confidence: 100.0% Identity: 18% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1g9s chain A Region: 1 - 151 Aligned: 147 Modelled: 151 Confidence: 99.9% Identity: 19% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1yfz chain A Region: 1 - 150 Aligned: 149 Modelled: 150 Confidence: 99.9% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis Phyre2 PDB 1yfz chain A domain 1 Region: 1 - 150 Aligned: 149 Modelled: 150 Confidence: 99.9% Identity: 23% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1hgx chain A Region: 1 - 150 Aligned: 143 Modelled: 150 Confidence: 99.9% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1z7g chain A domain 1 Region: 3 - 150 Aligned: 145 Modelled: 148 Confidence: 99.9% Identity: 16% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 3o7m chain D Region: 3 - 151 Aligned: 144 Modelled: 149 Confidence: 99.9% Identity: 24% PDB header:transferase Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor' Phyre2 PDB 1pzm chain B Region: 1 - 150 Aligned: 146 Modelled: 150 Confidence: 99.9% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp Phyre2 PDB 1j7j chain A Region: 4 - 151 Aligned: 144 Modelled: 148 Confidence: 99.9% Identity: 15% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2jbh chain A Region: 3 - 150 Aligned: 148 Modelled: 148 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase domain-containing protein 1; PDBTitle: human phosphoribosyl transferase domain containing 1 Phyre2 PDB 2ywt chain A Region: 1 - 150 Aligned: 142 Modelled: 150 Confidence: 99.9% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hypoxanthine-guanine2 phosphoribosyltransferase with gmp from thermus3 thermophilus hb8 Phyre2 PDB 2igb chain A domain 1 Region: 1 - 140 Aligned: 140 Modelled: 140 Confidence: 99.9% Identity: 15% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 1 d1nula_ 2 c2jkzB_ 3 d1vdma1 4 c3kb8A_ 5 d1fsga_ 6 d1p17b_ 7 d1pzma_ 8 d1tc1a_ 9 d1cjba_ 10 d1g9sa_ 11 c1yfzA_ 12 d1yfza1 13 d1hgxa_ 14 d1z7ga1 15 c3o7mD_ 16 c1pzmB_ 17 d1j7ja_ 18 c2jbhA_ 19 c2ywtA_ 20 d2igba1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1nula_ 100.0 99 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 2 c2jkzB_ 100.0 17 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form) 3 d1vdma1 100.0 26 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 4 c3kb8A_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp 5 d1fsga_ 100.0 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 6 d1p17b_ 100.0 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 7 d1pzma_ 100.0 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 8 d1tc1a_ 100.0 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 9 d1cjba_ 100.0 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 10 d1g9sa_ 99.9 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 11 c1yfzA_ 99.9 23 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis 12 d1yfza1 99.9 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 13 d1hgxa_ 99.9 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 14 d1z7ga1 99.9 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 15 c3o7mD_ 99.9 24 PDB header:transferase Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor' 16 c1pzmB_ 99.9 19 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp 17 d1j7ja_ 99.9 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 18 c2jbhA_ 99.9 15 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase domain-containing protein 1; PDBTitle: human phosphoribosyl transferase domain containing 1 19 c2ywtA_ 99.9 21 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hypoxanthine-guanine2 phosphoribosyltransferase with gmp from thermus3 thermophilus hb8 20 d2igba1 99.9 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 21 d1dqna_ not modelled 99.9 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 22 d1a3ca_ not modelled 99.9 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 23 d1w30a_ not modelled 99.9 11 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 24 d1ufra_ not modelled 99.9 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 25 d1ecfa1 not modelled 99.7 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 26 d1gph11 not modelled 99.7 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 27 c1ecjB_ not modelled 99.7 19 PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer 28 d1g2qa_ not modelled 99.6 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 29 c1gph1_ not modelled 99.6 17 PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis 30 d1wd5a_ not modelled 99.6 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 31 d1zn7a1 not modelled 99.6 26 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 32 c2dy0A_ not modelled 99.6 22 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 33 d1o57a2 not modelled 99.5 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 34 c2wnsB_ not modelled 99.5 15 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 35 d1y0ba1 not modelled 99.5 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 36 c1o57A_ not modelled 99.5 17 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 37 c3mjdA_ not modelled 99.5 13 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis. 38 d1vcha1 not modelled 99.5 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 39 d1l1qa_ not modelled 99.5 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 40 d1mzva_ not modelled 99.5 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 41 c3n2lA_ not modelled 99.5 17 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961 42 d1lh0a_ not modelled 99.5 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 43 c2przB_ not modelled 99.5 16 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp 44 c2p1zA_ not modelled 99.4 13 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae 45 d1qb7a_ not modelled 99.4 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 46 d2aeea1 not modelled 99.4 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 47 c3dezA_ not modelled 99.4 17 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans 48 c2yzkC_ not modelled 99.4 19 PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix 49 c3lpnB_ not modelled 99.3 18 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp). 50 c3m3hA_ not modelled 99.3 16 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' 51 c3qw4B_ not modelled 99.1 16 PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase 52 c3efhB_ not modelled 99.1 18 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 53 c1dkrB_ not modelled 99.1 20 PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. 54 c2c4kD_ not modelled 99.0 17 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 55 c1u9yD_ not modelled 99.0 19 PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii 56 d1dkua2 not modelled 99.0 22 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 57 d2c4ka2 not modelled 99.0 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 58 d1u9ya2 not modelled 98.9 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 59 c3dahB_ not modelled 98.8 25 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei 60 c2e55D_ not modelled 98.7 16 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of aq2163 protein from aquifex aeolicus 61 c2ehjA_ not modelled 98.6 19 PDB header:transferase Chain: A: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of uracil phosphoribosyl transferase 62 d1o5oa_ not modelled 98.6 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 63 d1i5ea_ not modelled 98.6 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 64 c3dmpD_ not modelled 98.4 15 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei 65 d1bd3a_ not modelled 98.2 13 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 66 d1xtta1 not modelled 98.2 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 67 d1v9sa1 not modelled 98.0 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 68 d1u9ya1 not modelled 78.1 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 69 d2c4ka1 not modelled 63.6 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 70 d1dkua1 not modelled 61.9 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 71 d1u0sy_ not modelled 55.4 17 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 72 d1dcfa_ not modelled 55.0 11 Fold:Flavodoxin-like Superfamily:CheY-like Family:Receiver domain of the ethylene receptor 73 c3h5iA_ not modelled 47.3 17 PDB header:transcription Chain: A: PDB Molecule:response regulator/sensory box protein/ggdef PDBTitle: crystal structure of the n-terminal domain of a response2 regulator/sensory box/ggdef 3-domain protein from3 carboxydothermus hydrogenoformans 74 c3mmnA_ not modelled 46.4 18 PDB header:transferase Chain: A: PDB Molecule:histidine kinase homolog; PDBTitle: crystal structure of the receiver domain of the histidine kinase cki12 from arabidopsis thaliana complexed with mg2+ 75 c2v5iA_ not modelled 43.5 16 PDB header:viral protein Chain: A: PDB Molecule:salmonella typhimurium db7155 bacteriophage det7 PDBTitle: structure of the receptor-binding protein of bacteriophage2 det7: a podoviral tailspike in a myovirus 76 d1h3da1 not modelled 42.9 50 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 77 c3gl9B_ not modelled 41.1 17 PDB header:signaling protein Chain: B: PDB Molecule:response regulator; PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism 78 d1qo0d_ not modelled 39.1 7 Fold:Flavodoxin-like Superfamily:CheY-like Family:Positive regulator of the amidase operon AmiR 79 d1nvta1 not modelled 39.1 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 80 c2vd3B_ not modelled 36.7 36 PDB header:transferase Chain: B: PDB Molecule:atp phosphoribosyltransferase; PDBTitle: the structure of histidine inhibited hisg from2 methanobacterium thermoautotrophicum 81 d1d2na_ not modelled 35.2 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Extended AAA-ATPase domain 82 c3a0rB_ not modelled 34.8 13 PDB header:transferase Chain: B: PDB Molecule:response regulator; PDBTitle: crystal structure of histidine kinase thka (tm1359) in complex with2 response regulator protein trra (tm1360) 83 c3eodA_ not modelled 34.0 7 PDB header:signaling protein Chain: A: PDB Molecule:protein hnr; PDBTitle: crystal structure of n-terminal domain of e. coli rssb 84 c3lufB_ not modelled 31.4 5 PDB header:signaling protein Chain: B: PDB Molecule:two-component system response regulator/ggdef PDBTitle: structure of probable two-component system response2 regulator/ggdef domain protein 85 d1uf1a_ not modelled 31.3 10 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 86 d1k68a_ not modelled 31.0 4 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 87 c2zayA_ not modelled 31.0 13 PDB header:signaling protein Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans 88 c1z9vA_ not modelled 30.2 10 PDB header:unknown function Chain: A: PDB Molecule:conserved hypothetical protein mth0776; PDBTitle: solution structure of mth0776 from methanobacterium2 thermoautotrophicum (strain h) 89 d1ve4a1 not modelled 30.0 55 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 90 d1o63a_ not modelled 29.9 36 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 91 d1nh8a1 not modelled 27.8 36 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 92 c3lteH_ not modelled 27.7 16 PDB header:transcription Chain: H: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator (signal receiver domain) from2 bermanella marisrubri 93 c2nt3A_ not modelled 27.1 10 PDB header:signaling protein Chain: A: PDB Molecule:response regulator homolog; PDBTitle: receiver domain from myxococcus xanthus social motility protein frzs2 (y102a mutant) 94 c2ayxA_ not modelled 27.1 19 PDB header:transferase Chain: A: PDB Molecule:sensor kinase protein rcsc; PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain 95 d1z7me1 not modelled 26.9 55 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 96 c2ekdD_ not modelled 26.6 30 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein ph0250; PDBTitle: structural study of project id ph0250 from pyrococcus horikoshii ot3 97 c3k1rA_ not modelled 25.6 15 PDB header:structural protein Chain: A: PDB Molecule:harmonin; PDBTitle: structure of harmonin npdz1 in complex with the sam-pbm of2 sans 98 d1vmea1 not modelled 25.0 8 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 99 d1p77a1 not modelled 24.0 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 100 d1peya_ not modelled 23.9 21 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 101 c1q1kA_ not modelled 23.8 64 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase; PDBTitle: structure of atp-phosphoribosyltransferase from e. coli complexed with2 pr-atp 102 c3khtA_ not modelled 23.7 13 PDB header:signaling protein Chain: A: PDB Molecule:response regulator; PDBTitle: crystal structure of response regulator from hahella chejuensis 103 c1sy7B_ not modelled 23.6 9 PDB header:oxidoreductase Chain: B: PDB Molecule:catalase 1; PDBTitle: crystal structure of the catalase-1 from neurospora crassa, native2 structure at 1.75a resolution. 104 d1dbwa_ not modelled 23.1 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 105 c2rjnA_ not modelled 23.1 8 PDB header:hydrolase Chain: A: PDB Molecule:response regulator receiver:metal-dependent PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis 106 c1nh7A_ not modelled 22.8 36 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase; PDBTitle: atp phosphoribosyltransferase (atp-prtase) from mycobacterium2 tuberculosis 107 d2ayxa1 not modelled 22.6 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 108 c3tqrA_ not modelled 22.5 14 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: structure of the phosphoribosylglycinamide formyltransferase (purn) in2 complex with ches from coxiella burnetii 109 d1mb3a_ not modelled 22.4 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 110 c3hjbA_ not modelled 22.3 9 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: 1.5 angstrom crystal structure of glucose-6-phosphate isomerase from2 vibrio cholerae. 111 d1gm5a3 not modelled 22.2 25 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 112 c3o82B_ not modelled 21.9 15 PDB header:ligase Chain: B: PDB Molecule:peptide arylation enzyme; PDBTitle: structure of base n-terminal domain from acinetobacter baumannii bound2 to 5'-o-[n-(2,3-dihydroxybenzoyl)sulfamoyl] adenosine 113 c3rqiA_ not modelled 21.8 26 PDB header:transcription Chain: A: PDB Molecule:response regulator protein; PDBTitle: crystal structure of a response regulator protein from burkholderia2 pseudomallei with a phosphorylated aspartic acid, calcium ion and3 citrate 114 c3g7sA_ not modelled 21.7 10 PDB header:ligase Chain: A: PDB Molecule:long-chain-fatty-acid--coa ligase (fadd-1); PDBTitle: crystal structure of a long-chain-fatty-acid-coa ligase2 (fadd1) from archaeoglobus fulgidus 115 d1zesa1 not modelled 21.6 13 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 116 d1w25a2 not modelled 20.9 21 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 117 c3luaA_ not modelled 20.9 13 PDB header:transcription regulator Chain: A: PDB Molecule:response regulator receiver protein; PDBTitle: crystal structure of a signal receiver domain of two component signal2 transduction (histidine kinase) from clostridium thermocellum 118 c3cg0A_ not modelled 20.8 18 PDB header:lyase Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding 119 c3ilhA_ not modelled 20.7 20 PDB header:transcription regulator Chain: A: PDB Molecule:two component response regulator; PDBTitle: crystal structure of two component response regulator from cytophaga2 hutchinsonii 120 d2a9pa1 not modelled 20.1 9 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0