Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	I	I	M	L	I	P	T	G	T	S	V	G	L	T	S	V	S	L	G	V	I	R	A	M	E	R	K	G	V	R	L	S	V	F	K	P	I	A	Q	P	R	T	G	G	D	A	P	D	Q	T	T	T	I	V	R	A	N
Secondary structure
SS confidence
Disorder		?	?	?	?																																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	S	T	T	T	A	A	E	P	L	K	M	S	Y	V	E	G	L	L	S	S	N	Q	K	D	V	L	M	E	E	I	V	A	N	Y	H	A	N	T	K	D	A	E	V	V	L	V	E	G	L	V	P	T	R	K	H	Q	F	A	Q
Secondary structure
SS confidence
Disorder			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	L	N	Y	E	I	A	K	T	L	N	A	E	I	V	F	V	M	S	Q	G	T	D	T	P	E	Q	L	K	E	R	I	E	L	T	R	N	S	F	G	G	A	K	N	T	N	I	T	G	V	I	V	N	K	L	N	A	P	V	D
Secondary structure
SS confidence
Disorder																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	Q	G	R	T	R	P	D	L	S	E	I	F	D	D	S	S	K	A	K	V	N	N	V	D	P	A	K	L	Q	E	S	S	P	L	P	V	L	G	A	V	P	W	S	F	D	L	I	A	T	R	A	I	D	M	A	R	H	L	N
Secondary structure
SS confidence
Disorder																												?				?	?	?												?		?							?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	T	I	I	N	E	G	D	I	N	T	R	R	V	K	S	V	T	F	C	A	R	S	I	P	H	M	L	E	H	F	R	A	G	S	L	L	V	T	S	A	D	R	P	D	V	L	V	A	A	C	L	A	A	M	N	G	V	E	I
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?																																											?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	A	L	L	L	T	G	G	Y	E	M	D	A	R	I	S	K	L	C	E	R	A	F	A	T	G	L	P	V	F	M	V	N	T	N	T	W	Q	T	S	L	S	L	Q	S	F	N	L	E	V	P	V	D	D	H	E	R	I	E	K
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		V	Q	E	Y	V	A	N	Y	I	N	A	D	W	I	E	S	L	T	A	T	S	E	R	S	R	R	L	S	P	P	A	F	R	Y	Q	L	T	E	L	A	R	K	A	G	K	R	I	V	L	P	E	G	D	E	P	R	T	V	K	A
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		A	A	I	C	A	E	R	G	I	A	T	C	V	L	L	G	N	P	A	E	I	N	R	V	A	A	S	Q	G	V	E	L	G	A	G	I	E	I	V	D	P	E	V	V	R	E	S	Y	V	G	R	L	V	E	L	R	K	N	K	G
Secondary structure
SS confidence
Disorder																																																										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		M	T	E	T	V	A	R	E	Q	L	E	D	N	V	V	L	G	T	L	M	L	E	Q	D	E	V	D	G	L	V	S	G	A	V	H	T	T	A	N	T	I	R	P	P	L	Q	L	I	K	T	A	P	G	S	S	L	V	S	S	V
Secondary structure
SS confidence
Disorder		?	?																																														?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		F	F	M	L	L	P	E	Q	V	Y	V	Y	G	D	C	A	I	N	P	D	P	T	A	E	Q	L	A	E	I	A	I	Q	S	A	D	S	A	A	A	F	G	I	E	P	R	V	A	M	L	S	Y	S	T	G	T	S	G	A	G	S
Secondary structure
SS confidence
Disorder																																																						?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		D	V	E	K	V	R	E	A	T	R	L	A	Q	E	K	R	P	D	L	M	I	D	G	P	L	Q	Y	D	A	A	V	M	A	D	V	A	K	S	K	A	P	N	S	P	V	A	G	R	A	T	V	F	I	F	P	D	L	N	T	G
Secondary structure
SS confidence
Disorder		?																																					?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.
Sequence		N	T	T	Y	K	A	V	Q	R	S	A	D	L	I	S	I	G	P	M	L	Q	G	M	R	K	P	V	N	D	L	S	R	G	A	L	V	D	D	I	V	Y	T	I	A	L	T	A	I	Q	S	A	Q	Q	Q
Secondary structure
SS confidence
Disorder																?																	?			?															?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1vmi chain A Region: 388 - 708 Aligned: 319 Modelled: 321 Confidence: 100.0% Identity: 37% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Phosphotransacetylase Phyre2 PDB 1vmi chain A Region: 388 - 708 Aligned: 319 Modelled: 321 Confidence: 100.0% Identity: 37% PDB header:transferase Chain: A: PDB Molecule:putative phosphate acetyltransferase; PDBTitle: crystal structure of putative phosphate acetyltransferase2 (np_416953.1) from escherichia coli k12 at 2.32 a resolution Phyre2 PDB 1xco chain A Region: 392 - 710 Aligned: 317 Modelled: 319 Confidence: 100.0% Identity: 44% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Phosphotransacetylase Phyre2 PDB 2af4 chain C domain 1 Region: 390 - 714 Aligned: 322 Modelled: 325 Confidence: 100.0% Identity: 45% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Phosphotransacetylase Phyre2 PDB 1r5j chain A Region: 392 - 713 Aligned: 320 Modelled: 322 Confidence: 100.0% Identity: 43% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: Phosphotransacetylase Phyre2 PDB 3tng chain A Region: 400 - 712 Aligned: 275 Modelled: 287 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:lmo1369 protein; PDBTitle: the crystal structure of a possible phosphate acetyl/butaryl2 transferase from listeria monocytogenes egd-e. Phyre2 PDB 1yco chain A Region: 406 - 713 Aligned: 270 Modelled: 282 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:branched-chain phosphotransacylase; PDBTitle: crystal structure of a branched-chain phosphotransacylase from2 enterococcus faecalis v583 Phyre2 PDB 1vi1 chain A Region: 406 - 713 Aligned: 287 Modelled: 290 Confidence: 100.0% Identity: 15% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: PlsX-like Phyre2 PDB 1u7n chain A Region: 405 - 713 Aligned: 268 Modelled: 294 Confidence: 100.0% Identity: 24% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: PlsX-like Phyre2 PDB 3fmf chain A Region: 3 - 246 Aligned: 217 Modelled: 222 Confidence: 99.9% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of mycobacterium tuberculosis dethiobiotin2 synthetase complexed with 7,8 diaminopelargonic acid carbamate Phyre2 PDB 1byi chain A Region: 2 - 227 Aligned: 201 Modelled: 206 Confidence: 99.9% Identity: 19% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 PDB 3of5 chain A Region: 3 - 239 Aligned: 210 Modelled: 217 Confidence: 99.9% Identity: 14% PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of a dethiobiotin synthetase from francisella2 tularensis subsp. tularensis schu s4 Phyre2 PDB 2qmo chain A Region: 2 - 232 Aligned: 208 Modelled: 213 Confidence: 99.9% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of dethiobiotin synthetase (biod) from helicobacter2 pylori Phyre2 PDB 2ioj chain A domain 1 Region: 229 - 353 Aligned: 117 Modelled: 125 Confidence: 99.9% Identity: 25% Fold: MurF and HprK N-domain-like Superfamily: HprK N-terminal domain-like Family: DRTGG domain Phyre2 PDB 1ptm chain A Region: 403 - 714 Aligned: 287 Modelled: 312 Confidence: 99.8% Identity: 17% Fold: Isocitrate/Isopropylmalate dehydrogenase-like Superfamily: Isocitrate/Isopropylmalate dehydrogenase-like Family: PdxA-like Phyre2 PDB 2ph1 chain A Region: 2 - 228 Aligned: 205 Modelled: 224 Confidence: 99.8% Identity: 10% PDB header:ligand binding protein Chain: A: PDB Molecule:nucleotide-binding protein; PDBTitle: crystal structure of nucleotide-binding protein af2382 from2 archaeoglobus fulgidus, northeast structural genomics target gr165 Phyre2 PDB 3la6 chain P Region: 1 - 185 Aligned: 174 Modelled: 180 Confidence: 99.8% Identity: 14% PDB header:transferase Chain: P: PDB Molecule:tyrosine-protein kinase wzc; PDBTitle: octameric kinase domain of the e. coli tyrosine kinase wzc with bound2 adp Phyre2 PDB 2afh chain E domain 1 Region: 3 - 228 Aligned: 198 Modelled: 204 Confidence: 99.8% Identity: 13% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 PDB 3cio chain A Region: 2 - 181 Aligned: 169 Modelled: 175 Confidence: 99.8% Identity: 10% PDB header:signaling protein, transferase Chain: A: PDB Molecule:tyrosine-protein kinase etk; PDBTitle: the kinase domain of escherichia coli tyrosine kinase etk Phyre2 PDB 1ion chain A Region: 1 - 228 Aligned: 194 Modelled: 198 Confidence: 99.8% Identity: 14% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: Nitrogenase iron protein-like Phyre2 1 d1vmia_ 2 c1vmiA_ 3 d1xcoa_ 4 d2af4c1 5 d1r5ja_ 6 c3tngA_ 7 c1ycoA_ 8 d1vi1a_ 9 d1u7na_ 10 c3fmfA_ 11 d1byia_ 12 c3of5A_ 13 c2qmoA_ 14 d2ioja1 15 d1ptma_ 16 c2ph1A_ 17 c3la6P_ 18 d2afhe1 19 c3cioA_ 20 d1iona_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499