Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	T	P	H	I	N	A	E	M	G	D	F	A	D	V	V	L	M	P	G	D	P	L	R	A	K	Y	I	A	E	T	F	L	E	D	A	R	E	V	N	N	V	R	G	M	L	G	F	T	G	T	Y	K	G	R	K	I	S	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	G	H	G	M	G	I	P	S	C	S	I	Y	T	K	E	L	I	T	D	F	G	V	K	K	I	I	R	V	G	S	C	G	A	V	L	P	H	V	K	L	R	D	V	V	I	G	M	G	A	C	T	D	S	K	V	N	R	I	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	K	D	H	D	F	A	A	I	A	D	F	D	M	V	R	N	A	V	D	A	A	K	A	L	G	I	D	A	R	V	G	N	L	F	S	A	D	L	F	Y	S	P	D	G	E	M	F	D	V	M	E	K	Y	G	I	L	G	V	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Sequence		M	E	A	A	G	I	Y	G	V	A	A	E	F	G	A	K	A	L	T	I	C	T	V	S	D	H	I	R	T	H	E	Q	T	T	A	A	E	R	Q	T	T	F	N	D	M	I	K	I	A	L	E	S	V	L	L	G	D	K	E
Secondary structure
SS confidence
Disorder																																?	?	?	?																						?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1k9s chain A Region: 2 - 238 Aligned: 237 Modelled: 237 Confidence: 100.0% Identity: 100% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1vhw chain A Region: 2 - 238 Aligned: 237 Modelled: 237 Confidence: 100.0% Identity: 80% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1z34 chain A Region: 2 - 236 Aligned: 230 Modelled: 235 Confidence: 100.0% Identity: 59% PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine Phyre2 PDB 1odk chain A Region: 2 - 236 Aligned: 228 Modelled: 235 Confidence: 100.0% Identity: 36% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3bje chain A Region: 2 - 234 Aligned: 233 Modelled: 233 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: A: PDB Molecule:nucleoside phosphorylase, putative; PDBTitle: crystal structure of trypanosoma brucei nucleoside phosphorylase shows2 uridine phosphorylase activity Phyre2 PDB 3tl6 chain B Region: 2 - 233 Aligned: 217 Modelled: 232 Confidence: 100.0% Identity: 48% PDB header:transferase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from entamoeba2 histolytica Phyre2 PDB 2ac7 chain A domain 1 Region: 3 - 232 Aligned: 219 Modelled: 230 Confidence: 100.0% Identity: 58% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1je0 chain A Region: 4 - 235 Aligned: 223 Modelled: 232 Confidence: 100.0% Identity: 33% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3mb8 chain A Region: 2 - 239 Aligned: 235 Modelled: 238 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from toxoplasma2 gondii in complex with immucillin-h Phyre2 PDB 1rxy chain A Region: 4 - 236 Aligned: 230 Modelled: 233 Confidence: 100.0% Identity: 28% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3qpb chain B Region: 2 - 239 Aligned: 235 Modelled: 238 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily Phyre2 PDB 1nw4 chain C Region: 3 - 236 Aligned: 231 Modelled: 234 Confidence: 100.0% Identity: 27% PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase, putative; PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate Phyre2 PDB 1q1g chain A Region: 3 - 236 Aligned: 231 Modelled: 234 Confidence: 100.0% Identity: 27% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 2xrf chain A Region: 3 - 233 Aligned: 228 Modelled: 230 Confidence: 100.0% Identity: 23% PDB header:transferase Chain: A: PDB Molecule:uridine phosphorylase 2; PDBTitle: crystal structure of human uridine phosphorylase 2 Phyre2 PDB 3euf chain C Region: 3 - 234 Aligned: 230 Modelled: 232 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase 1; PDBTitle: crystal structure of bau-bound human uridine phosphorylase 1 Phyre2 PDB 1ybf chain A Region: 5 - 236 Aligned: 223 Modelled: 232 Confidence: 100.0% Identity: 15% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3nm5 chain B Region: 15 - 234 Aligned: 219 Modelled: 220 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:mta/sah nucleosidase; PDBTitle: helicobacter pylori mtan complexed with formycin a Phyre2 PDB 1t8s chain A Region: 52 - 239 Aligned: 180 Modelled: 188 Confidence: 100.0% Identity: 19% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1zos chain E Region: 15 - 237 Aligned: 221 Modelled: 223 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma Phyre2 PDB 3bl6 chain A Region: 15 - 234 Aligned: 218 Modelled: 220 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a Phyre2 1 d1k9sa_ 2 d1vhwa_ 3 c1z34A_ 4 d1odka_ 5 c3bjeA_ 6 c3tl6B_ 7 d2ac7a1 8 d1je0a_ 9 c3mb8A_ 10 d1rxya_ 11 c3qpbB_ 12 c1nw4C_ 13 d1q1ga_ 14 c2xrfA_ 15 c3eufC_ 16 d1ybfa_ 17 c3nm5B_ 18 d1t8sa_ 19 c1zosE_ 20 c3bl6A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1k9sa_ 100.0 100 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 2 d1vhwa_ 100.0 80 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 3 c1z34A_ 100.0 59 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine 4 d1odka_ 100.0 36 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 5 c3bjeA_ 100.0 25 PDB header:transferase Chain: A: PDB Molecule:nucleoside phosphorylase, putative; PDBTitle: crystal structure of trypanosoma brucei nucleoside phosphorylase shows2 uridine phosphorylase activity 6 c3tl6B_ 100.0 48 PDB header:transferase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from entamoeba2 histolytica 7 d2ac7a1 100.0 58 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 8 d1je0a_ 100.0 33 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 9 c3mb8A_ 100.0 29 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from toxoplasma2 gondii in complex with immucillin-h 10 d1rxya_ 100.0 28 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 11 c3qpbB_ 100.0 31 PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily 12 c1nw4C_ 100.0 27 PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase, putative; PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate 13 d1q1ga_ 100.0 27 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 14 c2xrfA_ 100.0 23 PDB header:transferase Chain: A: PDB Molecule:uridine phosphorylase 2; PDBTitle: crystal structure of human uridine phosphorylase 2 15 c3eufC_ 100.0 22 PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase 1; PDBTitle: crystal structure of bau-bound human uridine phosphorylase 1 16 d1ybfa_ 100.0 15 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 17 c3nm5B_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:mta/sah nucleosidase; PDBTitle: helicobacter pylori mtan complexed with formycin a 18 d1t8sa_ 100.0 19 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 19 c1zosE_ 100.0 20 PDB header:hydrolase Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma 20 c3bl6A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a 21 c3eeiA_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:5-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of 5'-methylthioadenosine/s-2 adenosylhomocysteine nucleosidase from neisseria3 meningitidis in complex with methylthio-immucillin-a 22 c3dp9A_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:mta/sah nucleosidase; PDBTitle: crystal structure of vibrio cholerae 5'-methylthioadenosine/s-adenosyl2 homocysteine nucleosidase (mtan) complexed with butylthio-dadme-3 immucillin a 23 d1jysa_ not modelled 100.0 18 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 24 c2h8gA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase; PDBTitle: 5'-methylthioadenosine nucleosidase from arabidopsis2 thaliana 25 c3bsfB_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:at4g34840; PDBTitle: crystal structure of the mta/sah nucleosidase 26 c3ozbF_ not modelled 100.0 17 PDB header:transferase Chain: F: PDB Molecule:methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-methylthioinosine phosphorylase from2 psedomonas aeruginosa in complex with hypoxanthine 27 c3khsB_ not modelled 99.9 16 PDB header:hydrolase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of grouper iridovirus purine nucleoside2 phosphorylase 28 d1v4na_ not modelled 99.9 19 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 29 c1wtaA_ not modelled 99.9 19 PDB header:transferase Chain: A: PDB Molecule:5'-methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-deoxy-5'-methylthioadenosine from aeropyrum2 pernix (r32 form) 30 c3la8A_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:putative purine nucleoside phosphorylase; PDBTitle: the crystal structure of smu.1229 from streptococcus mutans ua159 31 d1g2oa_ not modelled 99.9 12 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 32 d1cb0a_ not modelled 99.9 16 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 33 c2p4sA_ not modelled 99.9 14 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: structure of purine nucleoside phosphorylase from anopheles gambiae in2 complex with dadme-immh 34 d1vmka_ not modelled 99.9 17 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 35 c1yr3A_ not modelled 99.9 15 PDB header:transferase Chain: A: PDB Molecule:xanthosine phosphorylase; PDBTitle: escherichia coli purine nucleoside phosphorylase ii, the2 product of the xapa gene 36 c1tcvB_ not modelled 99.9 19 PDB header:transferase Chain: B: PDB Molecule:purine-nucleoside phosphorylase; PDBTitle: crystal structure of the purine nucleoside phosphorylase2 from schistosoma mansoni in complex with non-detergent3 sulfobetaine 195 and acetate 37 d3bgsa1 not modelled 99.9 17 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 38 d1qe5a_ not modelled 99.9 11 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 39 c3ggsA_ not modelled 99.9 17 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: human purine nucleoside phosphorylase double mutant e201q,n243d2 complexed with 2-fluoro-2'-deoxyadenosine 40 d3pnpa_ not modelled 99.9 16 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 41 c1tvmA_ not modelled 71.7 8 PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system 42 c3czcA_ not modelled 45.7 16 PDB header:transferase Chain: A: PDB Molecule:rmpb; PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans 43 c3efhB_ not modelled 43.7 16 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 44 d2c4ka2 not modelled 40.8 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 45 c1vkrA_ not modelled 40.7 25 PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii 46 d1vkra_ not modelled 40.7 25 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 47 c2q1yB_ not modelled 40.5 18 PDB header:cell cycle, signaling protein Chain: B: PDB Molecule:cell division protein ftsz; PDBTitle: crystal structure of cell division protein ftsz from mycobacterium2 tuberculosis in complex with gtp-gamma-s 48 d1v58a2 not modelled 37.3 20 Fold:Cystatin-like Superfamily:DsbC/DsbG N-terminal domain-like Family:DsbC/DsbG N-terminal domain-like 49 c2f9iD_ not modelled 29.6 19 PDB header:transferase Chain: D: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl PDBTitle: crystal structure of the carboxyltransferase subunit of acc2 from staphylococcus aureus 50 d2csba3 not modelled 27.7 46 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:Topoisomerase V repeat domain 51 d1ea9c1 not modelled 26.0 27 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:E-set domains of sugar-utilizing enzymes 52 c1ii0A_ not modelled 24.6 35 PDB header:hydrolase Chain: A: PDB Molecule:arsenical pump-driving atpase; PDBTitle: crystal structure of the escherichia coli arsenite-translocating2 atpase 53 d1a4ia1 not modelled 23.5 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 54 d2a7sa2 not modelled 22.4 18 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 55 d2bm8a1 not modelled 21.1 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:CmcI-like 56 c3onoA_ not modelled 20.4 21 PDB header:isomerase Chain: A: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase lacab_rpib from2 vibrio parahaemolyticus 57 c3peiA_ not modelled 20.3 17 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis 58 c3giuA_ not modelled 20.2 7 PDB header:hydrolase Chain: A: PDB Molecule:pyrrolidone-carboxylate peptidase; PDBTitle: 1.25 angstrom crystal structure of pyrrolidone-carboxylate peptidase2 (pcp) from staphylococcus aureus 59 c3o38D_ not modelled 20.2 36 PDB header:oxidoreductase Chain: D: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase from mycobacterium2 smegmatis 60 c1a4iB_ not modelled 20.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase 61 d1dkua2 not modelled 19.5 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 62 d1wzla1 not modelled 19.4 22 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:E-set domains of sugar-utilizing enzymes 63 c1dkrB_ not modelled 19.3 13 PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. 64 d2bj7a2 not modelled 19.3 19 Fold:Ferredoxin-like Superfamily:ACT-like Family:Nickel responsive regulator NikR, C-terminal domain 65 d1gvia1 not modelled 18.7 33 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:E-set domains of sugar-utilizing enzymes 66 d1u9ya2 not modelled 18.7 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 67 d1x94a_ not modelled 18.7 20 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 68 c1w5fA_ not modelled 18.6 22 PDB header:cell division Chain: A: PDB Molecule:cell division protein ftsz; PDBTitle: ftsz, t7 mutated, domain swapped (t. maritima) 69 c2qlcC_ not modelled 18.4 17 PDB header:dna binding protein Chain: C: PDB Molecule:dna repair protein radc homolog; PDBTitle: the crystal structure of dna repair protein radc from chlorobium2 tepidum tls 70 c2bj3D_ not modelled 18.1 19 PDB header:transcription Chain: D: PDB Molecule:nickel responsive regulator; PDBTitle: nikr-apo 71 c2ppwA_ not modelled 18.1 21 PDB header:isomerase Chain: A: PDB Molecule:conserved domain protein; PDBTitle: the crystal structure of uncharacterized ribose 5-phosphate isomerase2 rpib from streptococcus pneumoniae 72 c1q5vB_ not modelled 17.8 22 PDB header:transcription Chain: B: PDB Molecule:nickel responsive regulator; PDBTitle: apo-nikr 73 c1e9yB_ not modelled 17.7 40 PDB header:hydrolase Chain: B: PDB Molecule:urease subunit beta; PDBTitle: crystal structure of helicobacter pylori urease in complex with2 acetohydroxamic acid 74 c3k7pA_ not modelled 17.7 21 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of mutant of ribose 5-phosphate isomerase type b from2 trypanosoma cruzi. 75 c3m1pA_ not modelled 17.7 21 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of ribose 5-phosphate isomerase type b from trypanosoma2 cruzi, soaked with allose-6-phosphate 76 d1q5ya_ not modelled 17.5 22 Fold:Ferredoxin-like Superfamily:ACT-like Family:Nickel responsive regulator NikR, C-terminal domain 77 d1j0ha1 not modelled 17.4 33 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:E-set domains of sugar-utilizing enzymes 78 c2ca9B_ not modelled 17.3 13 PDB header:transcriptional regulation Chain: B: PDB Molecule:putative nickel-responsive regulator; PDBTitle: apo-nikr from helicobacter pylori in closed trans-2 conformation 79 d1id0a_ not modelled 17.2 19 Fold:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Superfamily:ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Family:Histidine kinase 80 c3s5pA_ not modelled 17.1 43 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase b rpib from giardia2 lamblia 81 c3he8A_ not modelled 16.9 36 PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase; PDBTitle: structural study of clostridium thermocellum ribose-5-phosphate2 isomerase b 82 d2vvpa1 not modelled 16.9 29 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 83 d1b0aa1 not modelled 16.8 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 84 d1nn4a_ not modelled 16.6 36 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 85 d1sv6a_ not modelled 16.5 15 Fold:FAH Superfamily:FAH Family:FAH 86 c2y3yC_ not modelled 16.5 13 PDB header:transcription Chain: C: PDB Molecule:putative nickel-responsive regulator; PDBTitle: holo-ni(ii) hpnikr is a symmetric tetramer containing four2 canonic square-planar ni(ii) ions at physiological ph 87 d1b12a_ not modelled 16.5 14 Fold:LexA/Signal peptidase Superfamily:LexA/Signal peptidase Family:Type 1 signal peptidase 88 d1a2za_ not modelled 16.4 9 Fold:Phosphorylase/hydrolase-like Superfamily:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) Family:Pyrrolidone carboxyl peptidase (pyroglutamate aminopeptidase) 89 c2l2qA_ not modelled 16.3 18 PDB header:transferase Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela); PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi 90 c2equA_ not modelled 15.3 25 PDB header:protein binding Chain: A: PDB Molecule:phd finger protein 20-like 1; PDBTitle: solution structure of the tudor domain of phd finger2 protein 20-like 1 91 c2c4kD_ not modelled 15.1 16 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 92 c2jjyD_ not modelled 14.9 16 PDB header:oxidoreductase Chain: D: PDB Molecule:enoyl-[acyl-carrier-protein] reductase; PDBTitle: crystal structure of francisella tularensis enoyl reductase2 (ftfabi) with bound nad 93 d1sqsa_ not modelled 14.8 13 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Hypothetical protein SP1951 94 d2d1ya1 not modelled 14.6 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 95 c2qmoA_ not modelled 14.3 21 PDB header:ligase Chain: A: PDB Molecule:dethiobiotin synthetase; PDBTitle: crystal structure of dethiobiotin synthetase (biod) from helicobacter2 pylori 96 d2h7ma1 not modelled 14.2 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 97 d1fdra2 not modelled 14.0 10 Fold:Ferredoxin reductase-like, C-terminal NADP-linked domain Superfamily:Ferredoxin reductase-like, C-terminal NADP-linked domain Family:Reductases 98 d1rq2a1 not modelled 14.0 20 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 99 c3ngmB_ not modelled 13.8 21 PDB header:hydrolase Chain: B: PDB Molecule:extracellular lipase; PDBTitle: crystal structure of lipase from gibberella zeae

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0