Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	L	P	V	N	K	R	V	P	K	I	L	F	I	L	F	V	V	A	F	C	V	Y	L	V	P	R	V	A	I	N	F	F	Y	Y	P	D	D	K	I	Y	G	P	D	P	W	S	A	E	S	V	E	F	T	A	K	D	G	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	L	Q	G	W	F	I	P	S	S	T	G	P	A	D	N	A	I	A	T	I	I	H	A	H	G	N	A	G	N	M	S	A	H	W	P	L	V	S	W	L	P	E	R	N	F	N	V	F	M	F	D	Y	R	G	F	G	K	S	K
Secondary structure
SS confidence
Disorder												?	?	?	?	?																																											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	T	P	S	Q	A	G	L	L	D	D	T	Q	S	A	I	N	V	V	R	H	R	S	D	V	N	P	Q	R	L	V	L	F	G	Q	S	I	G	G	A	N	I	L	D	V	I	G	R	G	D	R	E	G	I	R	A	V	I	L	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	T	F	A	S	Y	A	T	I	A	N	Q	M	I	P	G	S	G	Y	L	L	D	E	S	Y	S	G	E	N	Y	I	A	S	V	S	P	I	P	L	L	L	I	H	G	K	A	D	H	V	I	P	W	Q	H	S	E	K	L	Y	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.
Sequence		L	A	K	E	P	K	R	L	I	L	I	P	D	G	E	H	I	D	A	F	S	D	R	H	G	D	V	Y	R	E	Q	M	V	D	F	I	L	S	A	L	N	P	Q	N
Secondary structure
SS confidence
Disorder																																								?		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ecf chain A Region: 44 - 282 Aligned: 236 Modelled: 239 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase iv; PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia Phyre2 PDB 3azq chain A Region: 37 - 280 Aligned: 241 Modelled: 241 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg Phyre2 PDB 2hu7 chain A Region: 49 - 281 Aligned: 227 Modelled: 232 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase Phyre2 PDB 2eep chain A Region: 48 - 280 Aligned: 230 Modelled: 233 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative; PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor Phyre2 PDB 1z68 chain A Region: 42 - 281 Aligned: 237 Modelled: 240 Confidence: 100.0% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit; PDBTitle: crystal structure of human fibroblast activation protein alpha Phyre2 PDB 2g5t chain A Region: 43 - 281 Aligned: 237 Modelled: 239 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag Phyre2 PDB 2qtb chain B Region: 47 - 282 Aligned: 234 Modelled: 236 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor Phyre2 PDB 1l7a chain A Region: 41 - 281 Aligned: 230 Modelled: 240 Confidence: 100.0% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Acetyl xylan esterase-like Phyre2 PDB 1qfm chain A Region: 37 - 280 Aligned: 243 Modelled: 244 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:protein (prolyl oligopeptidase); PDBTitle: prolyl oligopeptidase from porcine muscle Phyre2 PDB 2wtm chain C Region: 54 - 281 Aligned: 222 Modelled: 228 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus Phyre2 PDB 1qfm chain A domain 2 Region: 43 - 281 Aligned: 238 Modelled: 239 Confidence: 100.0% Identity: 17% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Prolyl oligopeptidase, C-terminal domain Phyre2 PDB 2hdw chain B Region: 38 - 280 Aligned: 239 Modelled: 243 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein pa2218; PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa Phyre2 PDB 1vlq chain A Region: 40 - 281 Aligned: 233 Modelled: 241 Confidence: 100.0% Identity: 20% Fold: alpha/beta-Hydrolases Superfamily: alpha/beta-Hydrolases Family: Acetyl xylan esterase-like Phyre2 PDB 3fcy chain B Region: 39 - 281 Aligned: 232 Modelled: 243 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:xylan esterase 1; PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485 Phyre2 PDB 2bkl chain B Region: 37 - 280 Aligned: 243 Modelled: 244 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:prolyl endopeptidase; PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity Phyre2 PDB 3qm1 chain A Region: 47 - 277 Aligned: 223 Modelled: 231 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:cinnamoyl esterase; PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii Phyre2 PDB 2xe4 chain A Region: 37 - 281 Aligned: 244 Modelled: 245 Confidence: 100.0% Identity: 15% PDB header:hydrolase/inhibitor Chain: A: PDB Molecule:oligopeptidase b; PDBTitle: structure of oligopeptidase b from leishmania major Phyre2 PDB 1xfd chain D Region: 46 - 281 Aligned: 235 Modelled: 236 Confidence: 100.0% Identity: 16% PDB header:membrane protein Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6; PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family Phyre2 PDB 3ksr chain A Region: 45 - 283 Aligned: 228 Modelled: 238 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:putative serine hydrolase; PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution Phyre2 PDB 2jbw chain B Region: 46 - 284 Aligned: 229 Modelled: 239 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. Phyre2 1 c2ecfA_ 2 c3azqA_ 3 c2hu7A_ 4 c2eepA_ 5 c1z68A_ 6 c2g5tA_ 7 c2qtbB_ 8 d1l7aa_ 9 c1qfmA_ 10 c2wtmC_ 11 d1qfma2 12 c2hdwB_ 13 d1vlqa_ 14 c3fcyB_ 15 c2bklB_ 16 c3qm1A_ 17 c2xe4A_ 18 c1xfdD_ 19 c3ksrA_ 20 c2jbwB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ecfA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase iv; PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia 2 c3azqA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase; PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg 3 c2hu7A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:acylamino-acid-releasing enzyme; PDBTitle: binding of inhibitors by acylaminoacyl peptidase 4 c2eepA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative; PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor 5 c1z68A_ 100.0 16 PDB header:lyase Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit; PDBTitle: crystal structure of human fibroblast activation protein alpha 6 c2g5tA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag 7 c2qtbB_ 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor 8 d1l7aa_ 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 9 c1qfmA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:protein (prolyl oligopeptidase); PDBTitle: prolyl oligopeptidase from porcine muscle 10 c2wtmC_ 100.0 20 PDB header:hydrolase Chain: C: PDB Molecule:est1e; PDBTitle: est1e from butyrivibrio proteoclasticus 11 d1qfma2 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Prolyl oligopeptidase, C-terminal domain 12 c2hdwB_ 100.0 23 PDB header:hydrolase Chain: B: PDB Molecule:hypothetical protein pa2218; PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa 13 d1vlqa_ 100.0 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acetyl xylan esterase-like 14 c3fcyB_ 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:xylan esterase 1; PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485 15 c2bklB_ 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:prolyl endopeptidase; PDBTitle: structural and mechanistic analysis of two prolyl2 endopeptidases: role of inter-domain dynamics in3 catalysis and specificity 16 c3qm1A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:cinnamoyl esterase; PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii 17 c2xe4A_ 100.0 15 PDB header:hydrolase/inhibitor Chain: A: PDB Molecule:oligopeptidase b; PDBTitle: structure of oligopeptidase b from leishmania major 18 c1xfdD_ 100.0 16 PDB header:membrane protein Chain: D: PDB Molecule:dipeptidyl aminopeptidase-like protein 6; PDBTitle: structure of a human a-type potassium channel accelerating factor2 dppx, a member of the dipeptidyl aminopeptidase family 19 c3ksrA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:putative serine hydrolase; PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution 20 c2jbwB_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase; PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase. 21 d2jbwa1 not modelled 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:2,6-dihydropseudooxynicotine hydrolase-like 22 d1hlga_ not modelled 100.0 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 23 d1k8qa_ not modelled 100.0 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Gastric lipase 24 c3jw8A_ not modelled 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:mgll protein; PDBTitle: crystal structure of human mono-glyceride lipase 25 d2fuka1 not modelled 100.0 21 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Atu1826-like 26 c3fnbB_ not modelled 100.0 20 PDB header:hydrolase Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737; PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159 27 c3iumA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:prolyl endopeptidase; PDBTitle: appep_wtx opened state 28 c3hjuB_ not modelled 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:monoglyceride lipase; PDBTitle: crystal structure of human monoglyceride lipase 29 c3mveB_ not modelled 99.9 14 PDB header:lyase Chain: B: PDB Molecule:upf0255 protein vv1_0328; PDBTitle: crystal structure of a novel pyruvate decarboxylase 30 d2hu7a2 not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Acylamino-acid-releasing enzyme, C-terminal donain 31 d1orva2 not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:DPP6 catalytic domain-like 32 c1cr6A_ not modelled 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor 33 c3h04A_ not modelled 99.9 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50 34 c3llcA_ not modelled 99.9 20 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution 35 d2bgra2 not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:DPP6 catalytic domain-like 36 d2i3da1 not modelled 99.9 21 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Atu1826-like 37 c2i3dA_ not modelled 99.9 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein atu1826; PDBTitle: crystal structure of protein of unknown function atu1826, a putative2 alpha/beta hydrolase from agrobacterium tumefaciens 38 c3trdA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase; PDBTitle: structure of an alpha-beta serine hydrolase homologue from coxiella2 burnetii 39 c1yr2A_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:prolyl oligopeptidase; PDBTitle: structural and mechanistic analysis of two prolyl endopeptidases: role2 of inter-domain dynamics in catalysis and specificity 40 d1ju3a2 not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:PepX catalytic domain-like 41 c3f67A_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:putative dienelactone hydrolase; PDBTitle: crystal structure of putative dienelactone hydrolase from klebsiella2 pneumoniae subsp. pneumoniae mgh 78578 42 d1a8qa_ not modelled 99.9 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 43 c2o2gA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:dienelactone hydrolase; PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution 44 d1b6ga_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloalkane dehalogenase 45 d1mtza_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 46 c3k2iA_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4; PDBTitle: human acyl-coenzyme a thioesterase 4 47 c3hlkB_ not modelled 99.9 18 PDB header:hydrolase Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial; PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2) 48 d1dina_ not modelled 99.9 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Dienelactone hydrolase 49 c3dyvA_ not modelled 99.9 11 PDB header:hydrolase Chain: A: PDB Molecule:esterase d; PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism 50 d1brta_ not modelled 99.9 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 51 d1xfda2 not modelled 99.9 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:DPP6 catalytic domain-like 52 d1cr6a2 not modelled 99.9 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 53 c1zoiC_ not modelled 99.9 21 PDB header:hydrolase Chain: C: PDB Molecule:esterase; PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996 54 d1a8sa_ not modelled 99.9 24 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 55 d1zd3a2 not modelled 99.9 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 56 c3bxpA_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:putative lipase/esterase; PDBTitle: crystal structure of a putative carboxylesterase (lp_2923) from2 lactobacillus plantarum wcfs1 at 1.70 a resolution 57 d1va4a_ not modelled 99.9 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 58 c2xt0A_ not modelled 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:haloalkane dehalogenase; PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i 59 d1tqha_ not modelled 99.9 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/lipase 60 d1a88a_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 61 c2vavL_ not modelled 99.9 14 PDB header:transferase Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak) 62 c3i1iA_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:homoserine o-acetyltransferase; PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis 63 c3doiA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:esterase; PDBTitle: crystal structure of a thermostable esterase complex with2 paraoxon 64 c3om8A_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:probable hydrolase; PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01 65 c3bwxA_ not modelled 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase; PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution 66 c2e3jA_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase ephb; PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom 67 d1ehya_ not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Epoxide hydrolase 68 c3v48B_ not modelled 99.9 15 PDB header:hydrolase Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd; PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli 69 d1q0ra_ not modelled 99.9 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Aclacinomycin methylesterase RdmC 70 d1ufoa_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hypothetical protein TT1662 71 c2cjpA_ not modelled 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:epoxide hydrolase; PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1) 72 c2y6vB_ not modelled 99.9 17 PDB header:hydrolase Chain: B: PDB Molecule:peroxisomal membrane protein lpx1; PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i) 73 d1wm1a_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 74 d2vata1 not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 75 d1azwa_ not modelled 99.9 20 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Proline iminopeptidase-like 76 c2r11D_ not modelled 99.9 14 PDB header:hydrolase Chain: D: PDB Molecule:carboxylesterase np; PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution 77 c2yysA_ not modelled 99.9 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:proline iminopeptidase-related protein; PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8 78 c3ib3A_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:coce/nond family hydrolase; PDBTitle: crystal structure of sacol2612 - coce/nond family hydrolase from2 staphylococcus aureus 79 c2xuaH_ not modelled 99.9 21 PDB header:hydrolase Chain: H: PDB Molecule:3-oxoadipate enol-lactonase; PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400 80 c3hxkB_ not modelled 99.9 16 PDB header:hydrolase Chain: B: PDB Molecule:sugar hydrolase; PDBTitle: crystal structure of a sugar hydrolase (yeeb) from2 lactococcus lactis, northeast structural genomics3 consortium target kr108 81 c3u1tA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:dmma haloalkane dehalogenase; PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin 82 c3dqzB_ not modelled 99.9 16 PDB header:lyase Chain: B: PDB Molecule:alpha-hydroxynitrile lyase-like protein; PDBTitle: structure of the hydroxynitrile lyase from arabidopsis2 thaliana 83 c3fobA_ not modelled 99.9 22 PDB header:oxidoreductase Chain: A: PDB Molecule:bromoperoxidase; PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis 84 c2ockA_ not modelled 99.9 21 PDB header:hydrolase Chain: A: PDB Molecule:valacyclovir hydrolase; PDBTitle: crystal structure of valacyclovir hydrolase d123n mutant 85 c3qvmA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:olei00960; PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica 86 c1l7qA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:cocaine esterase; PDBTitle: ser117ala mutant of bacterial cocaine esterase coce 87 c3oosA_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase family protein; PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne 88 d1e89a_ not modelled 99.9 15 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 89 d1hkha_ not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Haloperoxidase 90 d3c70a1 not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 91 c2vf2A_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis 92 c2c7bA_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:carboxylesterase; PDBTitle: the crystal structure of este1, a new thermophilic and2 thermostable carboxylesterase cloned from a metagenomic3 library 93 d1c4xa_ not modelled 99.9 17 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 94 d2b61a1 not modelled 99.9 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:O-acetyltransferase 95 c3h2iA_ not modelled 99.9 17 PDB header:hydrolase Chain: A: PDB Molecule:esterase; PDBTitle: crystal structure of n228w mutant of the rice cell wall2 degrading esterase lipa from xanthomonas oryzae 96 c3bdiA_ not modelled 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein ta0194; PDBTitle: crystal structure of predicted cib-like hydrolase (np_393672.1) from2 thermoplasma acidophilum at 1.45 a resolution 97 d1jkma_ not modelled 99.9 13 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase 98 c3nwoA_ not modelled 99.9 15 PDB header:hydrolase Chain: A: PDB Molecule:proline iminopeptidase; PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis 99 d1uxoa_ not modelled 99.9 14 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:YdeN-like 100 c3kdaB_ not modelled 99.9 18 PDB header:hydrolase Chain: B: PDB Molecule:cftr inhibitory factor (cif); PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation 101 d2rhwa1 not modelled 99.9 19 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 102 d1fj2a_ not modelled 99.9 16 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carboxylesterase/thioesterase 1 103 d1xkla_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Hydroxynitrile lyase-like 104 c3ed1E_ not modelled 99.9 13 PDB header:hydrolase receptor Chain: E: PDB Molecule:gibberellin receptor gid1; PDBTitle: crystal structure of rice gid1 complexed with ga3 105 c2qruA_ not modelled 99.9 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis 106 c2qmqA_ not modelled 99.9 12 PDB header:signaling protein Chain: A: PDB Molecule:protein ndrg2; PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution 107 c3kxpD_ not modelled 99.9 17 PDB header:hydrolase Chain: D: PDB Molecule:alpha-(n-acetylaminomethylene)succinic acid PDBTitle: crystal structure of e-2-(acetamidomethylene)succinate2 hydrolase 108 c1u2eA_ not modelled 99.9 16 PDB header:hydrolase Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid PDBTitle: crystal structure of the c-c bond hydrolase mhpc 109 c3r0vA_ not modelled 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:alpha/beta hydrolase fold protein; PDBTitle: the crystal structure of an alpha/beta hydrolase from sphaerobacter2 thermophilus dsm 20745. 110 c2wirB_ not modelled 99.9 14 PDB header:hydrolase Chain: B: PDB Molecule:alpha/beta hydrolase fold-3 domain protein; PDBTitle: hyperthermophilic esterase from the archeon pyrobaculum2 calidifontis 111 c3e0xB_ not modelled 99.9 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:lipase-esterase related protein; PDBTitle: the crystal structure of a lipase-esterase related protein2 from clostridium acetobutylicum atcc 824 112 d1uk8a_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Carbon-carbon bond hydrolase 113 c3ga7A_ not modelled 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:acetyl esterase; PDBTitle: 1.55 angstrom crystal structure of an acetyl esterase from salmonella2 typhimurium 114 c3p2mA_ not modelled 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:possible hydrolase; PDBTitle: crystal structure of a novel esterase rv0045c from mycobacterium2 tuberculosis 115 c2wj4B_ not modelled 99.9 14 PDB header:oxidoreductase Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase; PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine 116 c2q0xA_ not modelled 99.9 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: alpha/beta hydrolase fold protein of unknown function 117 c3aikB_ not modelled 99.9 12 PDB header:hydrolase Chain: B: PDB Molecule:303aa long hypothetical esterase; PDBTitle: crystal structure of a hsl-like carboxylesterase from sulfolobus2 tokodaii 118 c2b9vB_ not modelled 99.9 17 PDB header:hydrolase Chain: B: PDB Molecule:alpha-amino acid ester hydrolase; PDBTitle: acetobacter turbidans alpha-amino acid ester hydrolase 119 c3gzjB_ not modelled 99.9 16 PDB header:hydrolase Chain: B: PDB Molecule:polyneuridine-aldehyde esterase; PDBTitle: crystal structure of polyneuridine aldehyde esterase2 complexed with 16-epi-vellosimine 120 d1jfra_ not modelled 99.9 18 Fold:alpha/beta-Hydrolases Superfamily:alpha/beta-Hydrolases Family:Lipase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0