Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	D	T	T	L	P	L	T	D	I	H	R	H	L	D	G	N	I	R	P	Q	T	I	L	E	L	G	R	Q	Y	N	I	S	L	P	A	Q	S	L	E	T	L	I	P	H	V	Q	V	I	A	N	E	P	D	L	V	S	F	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	K	L	D	W	G	V	K	V	L	A	S	L	D	A	C	R	R	V	A	F	E	N	I	E	D	A	A	R	H	G	L	H	Y	V	E	L	R	F	S	P	G	Y	M	A	M	A	H	Q	L	P	V	A	G	V	V	E	A	V	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	G	V	R	E	G	C	R	T	F	G	V	Q	A	K	L	I	G	I	M	S	R	T	F	G	E	A	A	C	Q	Q	E	L	E	A	F	L	A	H	R	D	Q	I	T	A	L	D	L	A	G	D	E	L	G	F	P	G	S	L	F
Secondary structure
SS confidence
Disorder											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	S	H	F	N	R	A	R	D	A	G	W	H	I	T	V	H	A	G	E	A	A	G	P	E	S	I	W	Q	A	I	R	E	L	G	A	E	R	I	G	H	G	V	K	A	I	E	D	R	A	L	M	D	F	L	A	E	Q	Q	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	I	E	S	C	L	T	S	N	I	Q	T	S	T	V	A	E	L	A	A	H	P	L	K	T	F	L	E	H	G	I	R	A	S	I	N	T	D	D	P	G	V	Q	G	V	D	I	I	H	E	Y	T	V	A	A	P	A	A	G	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.
Sequence		S	R	E	Q	I	R	Q	A	Q	I	N	G	L	E	M	A	F	L	S	A	E	E	K	R	A	L	R	E	K	V	A	A	K
Secondary structure
SS confidence
Disorder																																	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3rys chain A Region: 4 - 332 Aligned: 324 Modelled: 329 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase 1; PDBTitle: the crystal structure of adenine deaminase (aaur1117) from2 arthrobacter aurescens Phyre2 PDB 2amx chain A domain 1 Region: 5 - 330 Aligned: 323 Modelled: 326 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Adenosine/AMP deaminase Phyre2 PDB 1vfl chain A domain 1 Region: 5 - 332 Aligned: 326 Modelled: 328 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Adenosine/AMP deaminase Phyre2 PDB 1a4m chain A Region: 5 - 333 Aligned: 328 Modelled: 329 Confidence: 100.0% Identity: 32% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Adenosine/AMP deaminase Phyre2 PDB 3lgg chain A Region: 5 - 333 Aligned: 328 Modelled: 329 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase cecr1; PDBTitle: crystal structure of human adenosine deaminase growth factor,2 adenosine deaminase type 2 (ada2) complexed with transition state3 analogue, coformycin Phyre2 PDB 3ou8 chain B Region: 5 - 318 Aligned: 309 Modelled: 314 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: B: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa Phyre2 PDB 3ou8 chain A Region: 5 - 316 Aligned: 307 Modelled: 312 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa Phyre2 PDB 2a3l chain A domain 1 Region: 7 - 327 Aligned: 315 Modelled: 321 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Adenosine/AMP deaminase Phyre2 PDB 2a3l chain A Region: 7 - 327 Aligned: 315 Modelled: 321 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:amp deaminase; PDBTitle: x-ray structure of adenosine 5'-monophosphate deaminase from2 arabidopsis thaliana in complex with coformycin 5'-phosphate Phyre2 PDB 1p1m chain A domain 2 Region: 9 - 319 Aligned: 262 Modelled: 266 Confidence: 99.9% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: SAH/MTA deaminase-like Phyre2 PDB 2i9u chain A domain 2 Region: 7 - 315 Aligned: 264 Modelled: 264 Confidence: 99.8% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: SAH/MTA deaminase-like Phyre2 PDB 2imr chain A domain 2 Region: 7 - 319 Aligned: 261 Modelled: 264 Confidence: 99.8% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: DR0824-like Phyre2 PDB 2q09 chain A domain 2 Region: 7 - 321 Aligned: 283 Modelled: 297 Confidence: 99.7% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Imidazolonepropionase-like Phyre2 PDB 1ra0 chain A domain 2 Region: 7 - 319 Aligned: 281 Modelled: 289 Confidence: 99.7% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Cytosine deaminase catalytic domain Phyre2 PDB 2uz9 chain A domain 2 Region: 7 - 321 Aligned: 275 Modelled: 273 Confidence: 99.7% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: SAH/MTA deaminase-like Phyre2 PDB 2bb0 chain A domain 2 Region: 7 - 321 Aligned: 284 Modelled: 292 Confidence: 99.7% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Imidazolonepropionase-like Phyre2 PDB 2puz chain A domain 2 Region: 7 - 321 Aligned: 283 Modelled: 294 Confidence: 99.7% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Imidazolonepropionase-like Phyre2 PDB 2bb0 chain A Region: 2 - 320 Aligned: 288 Modelled: 296 Confidence: 99.6% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis Phyre2 PDB 3e0l chain B Region: 2 - 321 Aligned: 279 Modelled: 290 Confidence: 99.6% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase Phyre2 PDB 2q09 chain A Region: 2 - 321 Aligned: 290 Modelled: 319 Confidence: 99.6% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid Phyre2 1 c3rysA_ 2 d2amxa1 3 d1vfla1 4 d1a4ma_ 5 c3lggA_ 6 c3ou8B_ 7 c3ou8A_ 8 d2a3la1 9 c2a3lA_ 10 d1p1ma2 11 d2i9ua2 12 d2imra2 13 d2q09a2 14 d1ra0a2 15 d2uz9a2 16 d2bb0a2 17 d2puza2 18 c2bb0A_ 19 c3e0lB_ 20 c2q09A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3rysA_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase 1; PDBTitle: the crystal structure of adenine deaminase (aaur1117) from2 arthrobacter aurescens 2 d2amxa1 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 3 d1vfla1 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 4 d1a4ma_ 100.0 32 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 5 c3lggA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase cecr1; PDBTitle: crystal structure of human adenosine deaminase growth factor,2 adenosine deaminase type 2 (ada2) complexed with transition state3 analogue, coformycin 6 c3ou8B_ 100.0 29 PDB header:hydrolase Chain: B: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 7 c3ou8A_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 8 d2a3la1 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 9 c2a3lA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:amp deaminase; PDBTitle: x-ray structure of adenosine 5'-monophosphate deaminase from2 arabidopsis thaliana in complex with coformycin 5'-phosphate 10 d1p1ma2 99.9 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 11 d2i9ua2 99.8 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 12 d2imra2 99.8 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:DR0824-like 13 d2q09a2 99.7 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 14 d1ra0a2 99.7 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Cytosine deaminase catalytic domain 15 d2uz9a2 99.7 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 16 d2bb0a2 99.7 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 17 d2puza2 99.7 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 18 c2bb0A_ 99.6 16 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis 19 c3e0lB_ 99.6 15 PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase 20 c2q09A_ 99.6 17 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid 21 c2gokA_ not modelled 99.6 16 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution 22 d2paja2 not modelled 99.5 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 23 d2ooda2 not modelled 99.5 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 24 c1p1mA_ not modelled 99.5 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tm0936; PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine 25 c3hpaB_ not modelled 99.5 13 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea 26 c2imrA_ not modelled 99.5 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dr_0824; PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans 27 c2pajA_ not modelled 99.5 19 PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/guanine deaminase; PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea 28 c2i9uA_ not modelled 99.4 14 PDB header:hydrolase Chain: A: PDB Molecule:cytosine/guanine deaminase related protein; PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site 29 c3lsbA_ not modelled 99.4 16 PDB header:hydrolase Chain: A: PDB Molecule:triazine hydrolase; PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin 30 d2r8ca2 not modelled 99.4 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 31 c1r9yA_ not modelled 99.3 15 PDB header:hydrolase Chain: A: PDB Molecule:cytosine deaminase; PDBTitle: bacterial cytosine deaminase d314a mutant. 32 d3be7a2 not modelled 99.3 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 33 d2qs8a2 not modelled 99.3 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 34 c3lnpA_ not modelled 99.2 15 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465; PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica 35 c3v7pA_ not modelled 99.2 14 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein; PDBTitle: crystal structure of amidohydrolase nis_0429 (target efi-500396) from2 nitratiruptor sp. sb155-2 36 c3mduA_ not modelled 99.2 14 PDB header:hydrolase Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase; PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate 37 c3etkA_ not modelled 99.1 18 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus furiosus 38 c2oodA_ not modelled 99.1 15 PDB header:hydrolase Chain: A: PDB Molecule:blr3880 protein; PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum 39 c1xrfA_ not modelled 99.0 17 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution 40 c2vunC_ not modelled 99.0 16 PDB header:hydrolase Chain: C: PDB Molecule:enamidase; PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily 41 c3ighX_ not modelled 99.0 14 PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus horikoshii ot3 42 c2qt3A_ not modelled 98.9 15 PDB header:hydrolase Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase; PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn 43 d2p9ba2 not modelled 98.9 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 44 d1xrta2 not modelled 98.9 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 45 c2vc7A_ not modelled 98.6 14 PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities 46 c1pscA_ not modelled 98.6 16 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta 47 c2vr2A_ not modelled 98.6 16 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase 48 c2r8cB_ not modelled 98.5 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eaj56179 49 d2d2ja1 not modelled 98.5 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 50 c3ooqC_ not modelled 98.5 15 PDB header:hydrolase Chain: C: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of amidohydrolase from thermotoga maritima msb8 51 d1i0da_ not modelled 98.5 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 52 c3gnhA_ not modelled 98.4 18 PDB header:hydrolase Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672; PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine. 53 c2ftwA_ not modelled 98.4 16 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum 54 c2gseC_ not modelled 98.4 17 PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 55 c3pnzD_ not modelled 98.3 12 PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes 56 c3f4cA_ not modelled 98.3 16 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 57 c3dc8B_ not modelled 98.3 12 PDB header:hydrolase Chain: B: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti 58 c3nqbB_ not modelled 98.3 14 PDB header:hydrolase Chain: B: PDB Molecule:adenine deaminase 2; PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58) 59 d1zzma1 not modelled 98.2 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 60 c3rcmA_ not modelled 98.1 12 PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida 61 c3gipB_ not modelled 98.1 11 PDB header:hydrolase Chain: B: PDB Molecule:n-acyl-d-glutamate deacylase; PDBTitle: crystal structure of n-acyl-d-glutamate deacylase from2 bordetella bronchiseptica complexed with zinc, acetate and3 formate ions. 62 c1gkpD_ not modelled 98.1 9 PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 63 c3msrA_ not modelled 98.0 15 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolases; PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae 64 d1kcxa2 not modelled 98.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 65 c1nfgA_ not modelled 97.9 11 PDB header:hydrolase Chain: A: PDB Molecule:d-hydantoinase; PDBTitle: structure of d-hydantoinase 66 c1k1dF_ not modelled 97.9 9 PDB header:hydrolase Chain: F: PDB Molecule:d-hydantoinase; PDBTitle: crystal structure of d-hydantoinase 67 c3egjA_ not modelled 97.9 12 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: n-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae. 68 c3be7B_ not modelled 97.8 14 PDB header:hydrolase Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase; PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase 69 c2xioA_ not modelled 97.8 15 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a 70 c3k2gA_ not modelled 97.8 18 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 71 c2ogjB_ not modelled 97.8 15 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of a dihydroorotase 72 d1gkpa2 not modelled 97.8 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 73 c3ij6A_ not modelled 97.8 12 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from lactobacillus acidophilus 74 c3hm7A_ not modelled 97.7 11 PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 75 d1xwya1 not modelled 97.7 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 76 c2p50C_ not modelled 97.7 12 PDB header:hydrolase Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn 77 c3guwB_ not modelled 97.7 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 78 c3d6nA_ not modelled 97.7 14 PDB header:hydrolase/transferase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 79 c1gkrA_ not modelled 97.7 12 PDB header:hydrolase Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase; PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens 80 c3feqB_ not modelled 97.6 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eah89906 81 d2dvta1 not modelled 97.5 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 82 c2zc1A_ not modelled 97.5 22 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: organophosphorus hydrolase from deinococcus radiodurans 83 d1j6oa_ not modelled 97.5 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 84 d1bf6a_ not modelled 97.4 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 85 c2qs8A_ not modelled 97.4 19 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of a xaa-pro dipeptidase with bound2 methionine in the active site 86 c3qy6A_ not modelled 97.4 14 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase ywqe; PDBTitle: crystal structures of ywqe from bacillus subtilis and cpsb from2 streptococcus pneumoniae, unique metal-dependent tyrosine3 phosphatases 87 d2f6ka1 not modelled 97.4 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 88 c2aqoB_ not modelled 97.4 9 PDB header:hydrolase Chain: B: PDB Molecule:isoaspartyl dipeptidase; PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q 89 c3ipwA_ not modelled 97.3 15 PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica 90 d1yixa1 not modelled 97.3 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 91 c3e2vA_ not modelled 97.2 12 PDB header:hydrolase Chain: A: PDB Molecule:3'-5'-exonuclease; PDBTitle: crystal structure of an uncharacterized amidohydrolase from2 saccharomyces cerevisiae 92 c3e74D_ not modelled 97.2 12 PDB header:hydrolase Chain: D: PDB Molecule:allantoinase; PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center 93 c2p9bA_ not modelled 97.2 13 PDB header:hydrolase Chain: A: PDB Molecule:possible prolidase; PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum 94 c2wjeA_ not modelled 97.2 15 PDB header:hydrolase Chain: A: PDB Molecule:tyrosine-protein phosphatase cpsb; PDBTitle: crystal structure of the tyrosine phosphatase cps4b from2 steptococcus pneumoniae tigr4. 95 c2vhlB_ not modelled 97.1 14 PDB header:hydrolase Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: the three-dimensional structure of the n-acetylglucosamine-2 6-phosphate deacetylase from bacillus subtilis 96 d2ffia1 not modelled 96.9 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 97 c2gzxB_ not modelled 96.9 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. 98 c2w9mB_ not modelled 96.8 11 PDB header:dna replication Chain: B: PDB Molecule:polymerase x; PDBTitle: structure of family x dna polymerase from deinococcus2 radiodurans 99 c1rjqA_ not modelled 96.8 12 PDB header:hydrolase Chain: A: PDB Molecule:d-aminoacylase; PDBTitle: the crystal structure of the d-aminoacylase mutant d366a 100 c3mpgB_ not modelled 96.8 15 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: dihydroorotase from bacillus anthracis 101 d1onwa2 not modelled 96.6 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Isoaspartyl dipeptidase, catalytic domain 102 d2ftwa2 not modelled 96.4 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 103 d1ynya2 not modelled 96.3 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 104 c3nurA_ not modelled 96.3 12 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus 105 c2gwnA_ not modelled 96.2 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the structure of putative dihydroorotase from porphyromonas2 gingivalis. 106 c2y1hA_ not modelled 96.0 14 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn3; PDBTitle: crystal structure of the human tatd-domain protein 3 (tatdn3) 107 c3rhgA_ not modelled 95.8 11 PDB header:hydrolase Chain: A: PDB Molecule:putative phophotriesterase; PDBTitle: crystal structure of amidohydrolase pmi1525 (target efi-500319) from2 proteus mirabilis hi4320 108 c2fvmA_ not modelled 95.8 7 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine 109 d1k1da2 not modelled 95.2 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 110 c2z00A_ not modelled 95.0 15 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of dihydroorotase from thermus thermophilus 111 d4ubpc2 not modelled 94.9 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain 112 c3griB_ not modelled 94.8 16 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus 113 c2icsA_ not modelled 94.6 13 PDB header:hydrolase Chain: A: PDB Molecule:adenine deaminase; PDBTitle: crystal structure of an adenine deaminase 114 c2wm1A_ not modelled 94.5 10 PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis 115 d2icsa2 not modelled 92.8 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenine deaminase-like 116 c3cjpA_ not modelled 90.6 13 PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum 117 c3irsB_ not modelled 90.5 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica 118 c1o12B_ not modelled 90.3 11 PDB header:hydrolase Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetylglucosamine-6-phosphate2 deacetylase (tm0814) from thermotoga maritima at 2.5 a3 resolution 119 d2hbva1 not modelled 90.1 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 120 c2ubpC_ not modelled 88.6 14 PDB header:hydrolase Chain: C: PDB Molecule:protein (urease alpha subunit); PDBTitle: structure of native urease from bacillus pasteurii

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0