Phyre 2 Results for P33345

Email	l.a.kelley@imperial.ac.uk
Description	P33345
Date	Thu Jan 5 11:51:46 GMT 2012
Unique Job ID	2eb665d713b814dd

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2ra8A_

Top template information

PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein q64v53_bacfr;
PDBTitle: crystal structure of the q64v53_bacfr protein from bacteroides2 fragilis. northeast structural genomics consortium target bfr43

Confidence and coverage

Confidence:

99.8%

Coverage:

70 residues ( 6% of your sequence) have been modelled with 99.8% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M R H F I Y Q D E K S H K F R A V E Q Q G N E L H I S W G K V G T K G Q S Q I K S F S D A A A A A K A E L K L I A E K V

Secondary structure

SS confidence

Disorder ? ? ?
? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence K K G Y V E Q A K D N S L Q P S Q T V T G S L K V A D L S T I I Q E Q P S F V A E T R A P D K N T D A V L P W L A K D I

Secondary structure

SS confidence

Disorder ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ?
? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence A V V F P P E V V H T T L S H R R F P G V P V Q Q A D K L P Q L R R L A C S V S Q R D N K T A T F D F S A C S L E W Q N

Secondary structure

SS confidence

Disorder ? ? ?
? ? ?
?
?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence T V A Q A I S Q I D G L K T T Q L P S P V M A V L T A L E M K C T R Y K V R E D V M D Q I V Q E G G L E Y A T D V I I H

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence L Q Q I D I E W D Y A N N V I I I L P S G I A P S Y L E Q Y S R F E X R L R K H L S L T E E S L W Q K C A Q K L I A A I

Secondary structure

SS confidence

Disorder
?
? ? ?
? ?
? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence P H I P E W R Q P L I A L L L P E K P E I A H E I A Q R L L G Q K K L P S L E W L K I V A T D E H I L A S L E K Y H E P

Secondary structure

SS confidence

Disorder ? ? ?
?
?
?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence Y A I F D D Y Y C G A I W S A T V L Q E Q G V A A L P R F A P Y A A S D Y C A D V L R H I N H P F A L T L L I R V A G Q

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence T K R C H D R M T K A I A A F P H A A M A A L T E L L G Q K E E N S W R I M L M T M L I S Q P A L A E Q V I P W L S T P

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence A V A V L K S C Q Q Q L T Q P S N H A S A D L L P A V V V S P P W L S K K K K S P I P V L D L A P L G I E P I C Y L T E

Secondary structure

SS confidence

Disorder ?
? ? ? ? ?
? ? ? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence E I S N Q L L A K Y I W Y S K H I T V S H E E S T T N L L A R M G F Q R R I A G T Y I K A P E A V V E A W L N E D Y S T

Secondary structure

SS confidence

Disorder
?
?
?
?
?
? ?
?
? ? ? ? ? ? ? ? ? ?
? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence L L S E F K V F H S P T G H Y W Q L G I L T T L P L E K A V K A W N A L T L S P H T D T E Y S M L H F G L K G L P G L V

Secondary structure

SS confidence

Disorder
? ?
?
?
? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence N S L A R Y P Q E A L P I T N Y F A A S E L A P A V A R A F N K L K T L R E N A R S W L L K Y P E H A L T G L L P A A P

Secondary structure

SS confidence

Disorder
? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence G K A G E A Q D N A R A A L R M L T E N G H Q P L L Q E I A R R Y N Q P E V T D A V N A L L A L D P L D N H P T K I P T

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence L P A F Y Q P S L W T R P V L K A N A Q S L P D S A L L H L G E M L R F P Q E E A L Y P G L L Q V K D V C S A D S L A G

Secondary structure

SS confidence

Disorder
?
? ? ? ?
? ? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence F A W D L F T A W Q T A G A P S K E S W A F T A L G V L G N D D T A R K L T P L I R A W P G E S Q H K R A T V G L D I L

Secondary structure

SS confidence

Disorder
?
? ? ? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence A A I G S D I A L M Q L N G I A Q K L K F K A L Q E R A K E K I A D I A E S R E L T V A E L E D R L A P D L G L D D N G

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence S L L L D F G P R Q F T V S F D E T L K P F V R D V S G S R L K D L P K P N K S D D E T R A N D A V N R Y K L L K K D A

Secondary structure

SS confidence

Disorder
?
?
?
?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence R T I A A Q Q V A R L E S A M C L R R R W S L E N F Q L F L V E H P L V R H L T R R L I W G V Y S A E N Q L L A C F R V

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence A E D N S S S T A D D D L F T L P E G D I S I G T P H V L E I S P T D A A A F G Q L F A D Y E L L P P F R Q L D R N S Y

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence A L T E A E R N A S E L T R W A G R K C P S G R V M G L A N K G W I K G E P Q D G G W I G W M I K P L G R W S L I M E I

Secondary structure

SS confidence

Disorder
? ? ?
? ?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence D E G F A V G M S P A E L S A E Q L L S K L W L W E G K A E R Y G W G S N S T Q E A Q F S V I D A I T A S E L I N D I E

Secondary structure

SS confidence

Disorder
? ? ?
?
? ? ? ? ?

Disorder confidence

. . . .

Sequence A L F E

Secondary structure

SS confidence

Disorder
? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2ra8 chain A

Region: 2 - 71
Aligned: 70
Modelled: 70
Confidence: 99.8%
Identity: 50%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein q64v53_bacfr;
PDBTitle: crystal structure of the q64v53_bacfr protein from bacteroides2 fragilis. northeast structural genomics consortium target bfr43

Phyre2

PDB 2eoc chain A

Region: 24 - 66
Aligned: 43
Modelled: 43
Confidence: 98.2%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:poly [adp-ribose] polymerase 3;
PDBTitle: solution structure of the wgr domain from human poly [adp-2 ribose] polymerase-3

Phyre2

PDB 2cr9 chain A domain 1

Region: 24 - 66
Aligned: 43
Modelled: 43
Confidence: 97.5%
Identity: 28%
Fold: WGR domain-like
Superfamily: WGR domain-like
Family: WGR domain

Phyre2

PDB 3u5g chain B

Region: 1126 - 1172
Aligned: 47
Modelled: 47
Confidence: 41.6%
Identity: 13%
PDB header:ribosome
Chain: B: PDB Molecule:40s ribosomal protein s1-a;
PDBTitle: the structure of the eukaryotic ribosome at 3.0 a resolution

Phyre2

PDB 1y9q chain A

Region: 923 - 950
Aligned: 28
Modelled: 27
Confidence: 38.6%
Identity: 11%
PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, hth_3 family;
PDBTitle: crystal structure of hth_3 family transcriptional regulator2 from vibrio cholerae

Phyre2

PDB 2xzm chain 4

Region: 1126 - 1172
Aligned: 47
Modelled: 47
Confidence: 37.1%
Identity: 13%
PDB header:ribosome
Chain: 4: PDB Molecule:40s ribosomal protein s3a;
PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1

Phyre2

PDB 2bno chain A

Region: 921 - 950
Aligned: 30
Modelled: 30
Confidence: 34.9%
Identity: 23%
PDB header:oxidoreductase
Chain: A: PDB Molecule:epoxidase;
PDBTitle: the structure of hydroxypropylphosphonic acid epoxidase2 from s. wedmorenis.

Phyre2

PDB 1yzx chain B

Region: 892 - 967
Aligned: 76
Modelled: 76
Confidence: 33.7%
Identity: 14%
PDB header:transferase
Chain: B: PDB Molecule:glutathione s-transferase kappa 1;
PDBTitle: crystal structure of human kappa class glutathione2 transferase

Phyre2

PDB 1jjc chain B domain 1

Region: 938 - 978
Aligned: 38
Modelled: 41
Confidence: 30.5%
Identity: 16%
Fold: Putative DNA-binding domain
Superfamily: Putative DNA-binding domain
Family: Domains B1 and B5 of PheRS-beta, PheT

Phyre2

PDB 2awn chain A domain 1

Region: 970 - 996
Aligned: 26
Modelled: 27
Confidence: 29.8%
Identity: 15%
Fold: OB-fold
Superfamily: MOP-like
Family: ABC-transporter additional domain

Phyre2

PDB 1te4 chain A

Region: 861 - 932
Aligned: 67
Modelled: 72
Confidence: 28.7%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: ARM repeat
Family: PBS lyase HEAT-like repeat

Phyre2

PDB 2hf3 chain A domain 1

Region: 957 - 984
Aligned: 28
Modelled: 28
Confidence: 28.6%
Identity: 18%
Fold: Ribonuclease H-like motif
Superfamily: Actin-like ATPase domain
Family: Actin/HSP70

Phyre2

PDB 3oox chain A

Region: 921 - 999
Aligned: 73
Modelled: 79
Confidence: 24.1%
Identity: 19%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 2og-fe(ii) oxygenase family protein;
PDBTitle: crystal structure of a putative 2og-fe(ii) oxygenase family protein2 (cc_0200) from caulobacter crescentus at 1.44 a resolution

Phyre2

PDB 3f6w chain E

Region: 916 - 950
Aligned: 35
Modelled: 35
Confidence: 23.2%
Identity: 23%
PDB header:dna binding protein
Chain: E: PDB Molecule:xre-family like protein;
PDBTitle: xre-family like protein from pseudomonas syringae pv. tomato str.2 dc3000

Phyre2

PDB 2o38 chain A

Region: 923 - 950
Aligned: 28
Modelled: 28
Confidence: 22.7%
Identity: 18%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: putative xre family transcriptional regulator

Phyre2

PDB 2o38 chain A domain 1

Region: 923 - 950
Aligned: 28
Modelled: 28
Confidence: 22.7%
Identity: 18%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: NE1354

Phyre2

PDB 3op9 chain A

Region: 924 - 950
Aligned: 27
Modelled: 27
Confidence: 21.0%
Identity: 15%
PDB header:transcription regulator
Chain: A: PDB Molecule:pli0006 protein;
PDBTitle: crystal structure of transcriptional regulator from listeria innocua

Phyre2

PDB 3gkn chain A

Region: 953 - 1018
Aligned: 63
Modelled: 66
Confidence: 20.1%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:bacterioferritin comigratory protein;
PDBTitle: insights into the alkyl peroxide reduction activity of xanthomonas2 campestris bacterioferritin comigratory protein from the trapped3 intermediate/ligand complex structures

Phyre2

PDB 1xvl chain A domain 1

Region: 1002 - 1063
Aligned: 54
Modelled: 62
Confidence: 19.8%
Identity: 20%
Fold: Chelatase-like
Superfamily: "Helical backbone" metal receptor
Family: TroA-like

Phyre2

PDB 2a6c chain A domain 1

Region: 923 - 950
Aligned: 28
Modelled: 28
Confidence: 18.5%
Identity: 11%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: NE1354

Phyre2

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	R	H	F	I	Y	Q	D	E	K	S	H	K	F	R	A	V	E	Q	Q	G	N	E	L	H	I	S	W	G	K	V	G	T	K	G	Q	S	Q	I	K	S	F	S	D	A	A	A	A	A	K	A	E	L	K	L	I	A	E	K	V
Secondary structure
SS confidence
Disorder	?	?	?																														?	?	?	?	?	?	?	?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	K	K	G	Y	V	E	Q	A	K	D	N	S	L	Q	P	S	Q	T	V	T	G	S	L	K	V	A	D	L	S	T	I	I	Q	E	Q	P	S	F	V	A	E	T	R	A	P	D	K	N	T	D	A	V	L	P	W	L	A	K	D	I
Secondary structure
SS confidence
Disorder	?	?				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?	?	?	?	?	?	?	?	?		?	?	?	?	?	?	?	?									?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	A	V	V	F	P	P	E	V	V	H	T	T	L	S	H	R	R	F	P	G	V	P	V	Q	Q	A	D	K	L	P	Q	L	R	R	L	A	C	S	V	S	Q	R	D	N	K	T	A	T	F	D	F	S	A	C	S	L	E	W	Q	N
Secondary structure
SS confidence
Disorder	?	?	?														?	?	?																																			?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	T	V	A	Q	A	I	S	Q	I	D	G	L	K	T	T	Q	L	P	S	P	V	M	A	V	L	T	A	L	E	M	K	C	T	R	Y	K	V	R	E	D	V	M	D	Q	I	V	Q	E	G	G	L	E	Y	A	T	D	V	I	I	H
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?	?	?	?	?	?														?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	L	Q	Q	I	D	I	E	W	D	Y	A	N	N	V	I	I	I	L	P	S	G	I	A	P	S	Y	L	E	Q	Y	S	R	F	E	X	R	L	R	K	H	L	S	L	T	E	E	S	L	W	Q	K	C	A	Q	K	L	I	A	A	I
Secondary structure
SS confidence
Disorder															?							?	?	?																				?	?														?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	P	H	I	P	E	W	R	Q	P	L	I	A	L	L	L	P	E	K	P	E	I	A	H	E	I	A	Q	R	L	L	G	Q	K	K	L	P	S	L	E	W	L	K	I	V	A	T	D	E	H	I	L	A	S	L	E	K	Y	H	E	P
Secondary structure
SS confidence
Disorder	?	?	?		?																											?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	Y	A	I	F	D	D	Y	Y	C	G	A	I	W	S	A	T	V	L	Q	E	Q	G	V	A	A	L	P	R	F	A	P	Y	A	A	S	D	Y	C	A	D	V	L	R	H	I	N	H	P	F	A	L	T	L	L	I	R	V	A	G	Q
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	T	K	R	C	H	D	R	M	T	K	A	I	A	A	F	P	H	A	A	M	A	A	L	T	E	L	L	G	Q	K	E	E	N	S	W	R	I	M	L	M	T	M	L	I	S	Q	P	A	L	A	E	Q	V	I	P	W	L	S	T	P
Secondary structure
SS confidence
Disorder																										?	?	?	?	?	?	?	?	?											?															?
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	A	V	A	V	L	K	S	C	Q	Q	Q	L	T	Q	P	S	N	H	A	S	A	D	L	L	P	A	V	V	V	S	P	P	W	L	S	K	K	K	K	S	P	I	P	V	L	D	L	A	P	L	G	I	E	P	I	C	Y	L	T	E
Secondary structure
SS confidence
Disorder	?									?	?	?	?	?																		?	?	?	?	?	?	?	?	?	?			?						?
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	E	I	S	N	Q	L	L	A	K	Y	I	W	Y	S	K	H	I	T	V	S	H	E	E	S	T	T	N	L	L	A	R	M	G	F	Q	R	R	I	A	G	T	Y	I	K	A	P	E	A	V	V	E	A	W	L	N	E	D	Y	S	T
Secondary structure
SS confidence
Disorder												?			?		?																?		?			?	?		?			?	?	?	?	?	?	?	?	?	?		?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	L	L	S	E	F	K	V	F	H	S	P	T	G	H	Y	W	Q	L	G	I	L	T	T	L	P	L	E	K	A	V	K	A	W	N	A	L	T	L	S	P	H	T	D	T	E	Y	S	M	L	H	F	G	L	K	G	L	P	G	L	V
Secondary structure
SS confidence
Disorder												?	?									?													?				?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	N	S	L	A	R	Y	P	Q	E	A	L	P	I	T	N	Y	F	A	A	S	E	L	A	P	A	V	A	R	A	F	N	K	L	K	T	L	R	E	N	A	R	S	W	L	L	K	Y	P	E	H	A	L	T	G	L	L	P	A	A	P
Secondary structure
SS confidence
Disorder																																?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	G	K	A	G	E	A	Q	D	N	A	R	A	A	L	R	M	L	T	E	N	G	H	Q	P	L	L	Q	E	I	A	R	R	Y	N	Q	P	E	V	T	D	A	V	N	A	L	L	A	L	D	P	L	D	N	H	P	T	K	I	P	T
Secondary structure
SS confidence
Disorder				?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	L	P	A	F	Y	Q	P	S	L	W	T	R	P	V	L	K	A	N	A	Q	S	L	P	D	S	A	L	L	H	L	G	E	M	L	R	F	P	Q	E	E	A	L	Y	P	G	L	L	Q	V	K	D	V	C	S	A	D	S	L	A	G
Secondary structure
SS confidence
Disorder																?		?	?	?	?																?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	F	A	W	D	L	F	T	A	W	Q	T	A	G	A	P	S	K	E	S	W	A	F	T	A	L	G	V	L	G	N	D	D	T	A	R	K	L	T	P	L	I	R	A	W	P	G	E	S	Q	H	K	R	A	T	V	G	L	D	I	L
Secondary structure
SS confidence
Disorder												?																																		?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	A	A	I	G	S	D	I	A	L	M	Q	L	N	G	I	A	Q	K	L	K	F	K	A	L	Q	E	R	A	K	E	K	I	A	D	I	A	E	S	R	E	L	T	V	A	E	L	E	D	R	L	A	P	D	L	G	L	D	D	N	G
Secondary structure
SS confidence
Disorder				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	S	L	L	L	D	F	G	P	R	Q	F	T	V	S	F	D	E	T	L	K	P	F	V	R	D	V	S	G	S	R	L	K	D	L	P	K	P	N	K	S	D	D	E	T	R	A	N	D	A	V	N	R	Y	K	L	L	K	K	D	A
Secondary structure
SS confidence
Disorder																																				?		?		?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
Sequence	R	T	I	A	A	Q	Q	V	A	R	L	E	S	A	M	C	L	R	R	R	W	S	L	E	N	F	Q	L	F	L	V	E	H	P	L	V	R	H	L	T	R	R	L	I	W	G	V	Y	S	A	E	N	Q	L	L	A	C	F	R	V
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140
Sequence	A	E	D	N	S	S	S	T	A	D	D	D	L	F	T	L	P	E	G	D	I	S	I	G	T	P	H	V	L	E	I	S	P	T	D	A	A	A	F	G	Q	L	F	A	D	Y	E	L	L	P	P	F	R	Q	L	D	R	N	S	Y
Secondary structure
SS confidence
Disorder																				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200
Sequence	A	L	T	E	A	E	R	N	A	S	E	L	T	R	W	A	G	R	K	C	P	S	G	R	V	M	G	L	A	N	K	G	W	I	K	G	E	P	Q	D	G	G	W	I	G	W	M	I	K	P	L	G	R	W	S	L	I	M	E	I
Secondary structure
SS confidence
Disorder							?	?	?		?	?																			?	?	?	?	?			?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	D	E	G	F	A	V	G	M	S	P	A	E	L	S	A	E	Q	L	L	S	K	L	W	L	W	E	G	K	A	E	R	Y	G	W	G	S	N	S	T	Q	E	A	Q	F	S	V	I	D	A	I	T	A	S	E	L	I	N	D	I	E
Secondary structure
SS confidence
Disorder																													?	?	?		?		?	?	?	?	?
Disorder confidence

	.	.	.	.
Sequence	A	L	F	E
Secondary structure
SS confidence
Disorder			?	?
Disorder confidence