Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP69795
DateThu Jan 5 12:11:58 GMT 2012
Unique Job ID2777cb826fe15252

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1iiba_
Top template information
Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Lactose/Cellobiose specific IIB subunit
Confidence and coverage
Confidence:100.0% Coverage: 97%
103 residues ( 97% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLAGEKGQNADVVLLGPQI
Secondary structure 

















SS confidence 



























































Disorder  ????























































Disorder confidence 



























































 
   .........70.........80.........90.........100......
Sequence  AYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKKAAAN
Secondary structure 











SS confidence 













































Disorder 








































?????
Disorder confidence 













































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1iib chain A

3D model

Region: 3 - 105
Aligned: 103
Modelled: 103
Confidence: 100.0%
Identity: 99%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Lactose/Cellobiose specific IIB subunit

Phyre2

PDB 2l2q chain A

3D model

Region: 2 - 105
Aligned: 104
Modelled: 104
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela);
PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi

Phyre2

PDB 3nbm chain A

3D model

Region: 2 - 98
Aligned: 97
Modelled: 97
Confidence: 100.0%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:pts system, lactose-specific iibc components;
PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae.

Phyre2

PDB 1tvm chain A

3D model

Region: 2 - 101
Aligned: 92
Modelled: 100
Confidence: 99.3%
Identity: 11%
PDB header:transferase
Chain: A: PDB Molecule:pts system, galactitol-specific iib component;
PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system

Phyre2

PDB 3czc chain A

3D model

Region: 3 - 101
Aligned: 91
Modelled: 99
Confidence: 99.1%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:rmpb;
PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans

Phyre2

PDB 1vkr chain A

3D model

Region: 3 - 103
Aligned: 91
Modelled: 98
Confidence: 98.7%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components;
PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii

Phyre2

PDB 1vkr chain A

3D model

Region: 3 - 103
Aligned: 91
Modelled: 98
Confidence: 98.7%
Identity: 13%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Lactose/Cellobiose specific IIB subunit

Phyre2

PDB 2kyr chain A

3D model

Region: 9 - 104
Aligned: 92
Modelled: 96
Confidence: 96.5%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:fructose-like phosphotransferase enzyme iib component 1;
PDBTitle: solution structure of enzyme iib subunit of pts system from2 escherichia coli k12. northeast structural genomics consortium target3 er315/ontario center for structural proteomics target ec0544

Phyre2

PDB 2r48 chain A domain 1

3D model

Region: 9 - 98
Aligned: 85
Modelled: 90
Confidence: 96.5%
Identity: 13%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Fructose specific IIB subunit-like

Phyre2

PDB 1vme chain A domain 1

3D model

Region: 2 - 106
Aligned: 101
Modelled: 105
Confidence: 96.3%
Identity: 17%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: Flavodoxin-related

Phyre2

PDB 3fni chain A

3D model

Region: 2 - 106
Aligned: 101
Modelled: 104
Confidence: 96.2%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative diflavin flavoprotein a 3;
PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a

Phyre2

PDB 1ycg chain A domain 1

3D model

Region: 3 - 106
Aligned: 100
Modelled: 104
Confidence: 96.0%
Identity: 21%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: Flavodoxin-related

Phyre2

PDB 2r4q chain A domain 1

3D model

Region: 9 - 98
Aligned: 84
Modelled: 88
Confidence: 95.7%
Identity: 14%
Fold: Phosphotyrosine protein phosphatases I-like
Superfamily: PTS system IIB component-like
Family: PTS system, Fructose specific IIB subunit-like

Phyre2

PDB 3sqn chain B

3D model

Region: 2 - 81
Aligned: 65
Modelled: 68
Confidence: 95.7%
Identity: 15%
PDB header:transcription regulator
Chain: B: PDB Molecule:conserved domain protein;
PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis

Phyre2

PDB 1e5d chain A domain 1

3D model

Region: 3 - 106
Aligned: 100
Modelled: 104
Confidence: 95.3%
Identity: 17%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: Flavodoxin-related

Phyre2

PDB 2ohi chain B

3D model

Region: 1 - 104
Aligned: 100
Modelled: 104
Confidence: 94.9%
Identity: 17%
PDB header:oxidoreductase
Chain: B: PDB Molecule:type a flavoprotein fpra;
PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state

Phyre2

PDB 3rof chain A

3D model

Region: 3 - 41
Aligned: 39
Modelled: 39
Confidence: 94.1%
Identity: 10%
PDB header:hydrolase
Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa;
PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa

Phyre2

PDB 1vme chain B

3D model

Region: 2 - 105
Aligned: 100
Modelled: 104
Confidence: 93.8%
Identity: 16%
PDB header:electron transport
Chain: B: PDB Molecule:flavoprotein;
PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution

Phyre2

PDB 2gi4 chain A

3D model

Region: 3 - 40
Aligned: 38
Modelled: 38
Confidence: 93.6%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase;
PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni.

Phyre2

PDB 2ark chain A domain 1

3D model

Region: 5 - 104
Aligned: 99
Modelled: 98
Confidence: 93.4%
Identity: 10%
Fold: Flavodoxin-like
Superfamily: Flavoproteins
Family: WrbA-like

Phyre2
1

d1iiba_
2

c2l2qA_
3

c3nbmA_
4

c1tvmA_
5

c3czcA_
6

c1vkrA_
7

d1vkra_
8

c2kyrA_
9

d2r48a1
10

d1vmea1
11

c3fniA_
12

d1ycga1
13

d2r4qa1
14

c3sqnB_
15

d1e5da1
16

c2ohiB_
17

c3rofA_
18

c1vmeB_
19

c2gi4A_
20

d2arka1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1iiba_



100.0 99 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Lactose/Cellobiose specific IIB subunit
2c2l2qA_



100.0 35 PDB header:transferase
Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela);
PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi
3c3nbmA_



100.0 14 PDB header:transferase
Chain: A: PDB Molecule:pts system, lactose-specific iibc components;
PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae.
4c1tvmA_



99.3 11 PDB header:transferase
Chain: A: PDB Molecule:pts system, galactitol-specific iib component;
PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system
5c3czcA_



99.1 16 PDB header:transferase
Chain: A: PDB Molecule:rmpb;
PDBTitle: the crystal structure of a putative pts iib(ptxb) from2 streptococcus mutans
6c1vkrA_



98.7 13 PDB header:transferase
Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components;
PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii
7d1vkra_



98.7 13 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Lactose/Cellobiose specific IIB subunit
8c2kyrA_



96.5 15 PDB header:transferase
Chain: A: PDB Molecule:fructose-like phosphotransferase enzyme iib component 1;
PDBTitle: solution structure of enzyme iib subunit of pts system from2 escherichia coli k12. northeast structural genomics consortium target3 er315/ontario center for structural proteomics target ec0544
9d2r48a1



96.5 13 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Fructose specific IIB subunit-like
10d1vmea1



96.3 17 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
11c3fniA_



96.2 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative diflavin flavoprotein a 3;
PDBTitle: crystal structure of a diflavin flavoprotein a3 (all3895) from nostoc2 sp., northeast structural genomics consortium target nsr431a
12d1ycga1



96.0 21 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
13d2r4qa1



95.7 14 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:PTS system IIB component-like
Family:PTS system, Fructose specific IIB subunit-like
14c3sqnB_



95.7 15 PDB header:transcription regulator
Chain: B: PDB Molecule:conserved domain protein;
PDBTitle: putative mga family transcriptional regulator from enterococcus2 faecalis
15d1e5da1



95.3 17 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
16c2ohiB_



94.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:type a flavoprotein fpra;
PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state
17c3rofA_



94.1 10 PDB header:hydrolase
Chain: A: PDB Molecule:low molecular weight protein-tyrosine-phosphatase ptpa;
PDBTitle: crystal structure of the s. aureus protein tyrosine phosphatase ptpa
18c1vmeB_



93.8 16 PDB header:electron transport
Chain: B: PDB Molecule:flavoprotein;
PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution
19c2gi4A_



93.6 18 PDB header:hydrolase
Chain: A: PDB Molecule:possible phosphotyrosine protein phosphatase;
PDBTitle: solution structure of the low molecular weight protein2 tyrosine phosphatase from campylobacter jejuni.
20d2arka1



93.4 10 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:WrbA-like
21c3hlyA_



not modelled 93.4 20 PDB header:flavoprotein
Chain: A: PDB Molecule:flavodoxin-like domain;
PDBTitle: crystal structure of the flavodoxin-like domain from2 synechococcus sp q5mzp6_synp6 protein. northeast structural3 genomics consortium target snr135d.
22c3d7nA_



not modelled 91.1 16 PDB header:electron transport
Chain: A: PDB Molecule:flavodoxin, wrba-like protein;
PDBTitle: the crystal structure of the flavodoxin, wrba-like protein from2 agrobacterium tumefaciens
23d2fz5a1



not modelled 90.8 21 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
24c1ychD_



not modelled 88.8 19 PDB header:oxidoreductase
Chain: D: PDB Molecule:nitric oxide reductase;
PDBTitle: x-ray crystal structures of moorella thermoacetica fpra.2 novel diiron site structure and mechanistic insights into3 a scavenging nitric oxide reductase
25c1zggA_



not modelled 86.7 15 PDB header:hydrolase
Chain: A: PDB Molecule:putative low molecular weight protein-tyrosine-
PDBTitle: solution structure of a low molecular weight protein2 tyrosine phosphatase from bacillus subtilis
26c3rpeA_



not modelled 86.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:modulator of drug activity b;
PDBTitle: 1.1 angstrom crystal structure of putative modulator of drug activity2 (mdab) from yersinia pestis co92.
27d1fmfa_



not modelled 86.3 17 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
28d5pnta_



not modelled 85.9 10 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:Phosphotyrosine protein phosphatases I
Family:Low-molecular-weight phosphotyrosine protein phosphatases
29d1d1qa_



not modelled 85.9 15 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:Phosphotyrosine protein phosphatases I
Family:Low-molecular-weight phosphotyrosine protein phosphatases
30c2l18A_



not modelled 85.8 8 PDB header:oxidoreductase
Chain: A: PDB Molecule:arsenate reductase;
PDBTitle: an arsenate reductase in the phosphate binding state
31d1dg9a_



not modelled 85.7 13 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:Phosphotyrosine protein phosphatases I
Family:Low-molecular-weight phosphotyrosine protein phosphatases
32c3f6sI_



not modelled 85.4 15 PDB header:electron transport
Chain: I: PDB Molecule:flavodoxin;
PDBTitle: desulfovibrio desulfuricans (atcc 29577) oxidized flavodoxin2 alternate conformers
33c3cf4G_



not modelled 85.2 14 PDB header:oxidoreductase
Chain: G: PDB Molecule:acetyl-coa decarboxylase/synthase epsilon subunit;
PDBTitle: structure of the codh component of the m. barkeri acds complex
34d1p3da1



not modelled 85.1 20 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
35c2hnbA_



not modelled 84.9 9 PDB header:electron transport
Chain: A: PDB Molecule:protein mioc;
PDBTitle: solution structure of a bacterial holo-flavodoxin
36d1f4pa_



not modelled 84.0 17 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
37d5nula_



not modelled 82.8 15 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Flavodoxin-related
38c2f00A_



not modelled 82.5 18 PDB header:ligase
Chain: A: PDB Molecule:udp-n-acetylmuramate--l-alanine ligase;
PDBTitle: escherichia coli murc
39d1ydga_



not modelled 81.7 13 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:WrbA-like
40c1u2pA_



not modelled 80.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:low molecular weight protein-tyrosine-
PDBTitle: crystal structure of mycobacterium tuberculosis low2 molecular protein tyrosine phosphatase (mptpa) at 1.9a3 resolution
41c3jviA_



not modelled 79.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:protein tyrosine phosphatase;
PDBTitle: product state mimic crystal structure of protein tyrosine phosphatase2 from entamoeba histolytica
42d1t0ia_



not modelled 79.7 13 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:NADPH-dependent FMN reductase
43c1gqqA_



not modelled 77.9 24 PDB header:cell wall biosynthesis
Chain: A: PDB Molecule:udp-n-acetylmuramate-l-alanine ligase;
PDBTitle: murc - crystal structure of the apo-enzyme from haemophilus2 influenzae
44c2q9uB_



not modelled 77.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:a-type flavoprotein;
PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis
45c2zkiH_



not modelled 77.1 30 PDB header:transcription
Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding
PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872)
46d1qrda_



not modelled 77.0 20 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Quinone reductase
47c2cwdA_



not modelled 76.3 8 PDB header:hydrolase
Chain: A: PDB Molecule:low molecular weight phosphotyrosine protein phosphatase;
PDBTitle: crystal structure of tt1001 protein from thermus thermophilus hb8
48d1t5ba_



not modelled 76.2 22 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Quinone reductase
49d2qwxa1



not modelled 74.5 19 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Quinone reductase
50c2g76A_



not modelled 73.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
51d1q6za1



not modelled 73.5 25 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
52d2a5la1



not modelled 73.3 15 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:WrbA-like
53c3edoA_



not modelled 73.1 14 PDB header:flavoprotein
Chain: A: PDB Molecule:putative trp repressor binding protein;
PDBTitle: crystal structure of flavoprotein in complex with fmn2 (yp_193882.1) from lactobacillus acidophilus ncfm at 1.203 a resolution
54c3pg8B_



not modelled 72.9 23 PDB header:transferase
Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase;
PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima
55d1ccwa_



not modelled 70.5 19 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
56d1q1aa_



not modelled 70.3 36 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
57d1s5pa_



not modelled 69.0 27 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
58c3lcmB_



not modelled 68.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of smu.1420 from streptococcus mutans ua159
59c2jrlA_



not modelled 67.9 20 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulator (ntrc family);
PDBTitle: solution structure of the beryllofluoride-activated ntrc4 receiver2 domain dimer
60c2fekA_



not modelled 66.5 14 PDB header:hydrolase
Chain: A: PDB Molecule:low molecular weight protein-tyrosine-
PDBTitle: structure of a protein tyrosine phosphatase
61c1e5dA_



not modelled 66.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:rubredoxin\:oxygen oxidoreductase;
PDBTitle: rubredoxin oxygen:oxidoreductase (roo) from anaerobe2 desulfovibrio gigas
62c3ia7A_



not modelled 65.9 16 PDB header:transferase
Chain: A: PDB Molecule:calg4;
PDBTitle: crystal structure of calg4, the calicheamicin glycosyltransferase
63d1jf8a_



not modelled 64.1 14 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:Phosphotyrosine protein phosphatases I
Family:Low-molecular-weight phosphotyrosine protein phosphatases
64c3e18A_



not modelled 63.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of nad-binding protein from listeria innocua
65c1gpjA_



not modelled 61.9 17 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
66d2b4ya1



not modelled 61.8 43 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
67d1vl2a1



not modelled 61.4 24 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Adenine nucleotide alpha hydrolases-like
Family:N-type ATP pyrophosphatases
68c2wc1A_



not modelled 60.7 17 PDB header:electron transport
Chain: A: PDB Molecule:flavodoxin;
PDBTitle: three-dimensional structure of the nitrogen fixation2 flavodoxin (niff) from rhodobacter capsulatus at 2.2 a
69d1u11a_



not modelled 60.0 17 Fold:Flavodoxin-like
Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
70c2qsjB_



not modelled 59.6 14 PDB header:transcription
Chain: B: PDB Molecule:dna-binding response regulator, luxr family;
PDBTitle: crystal structure of a luxr family dna-binding response2 regulator from silicibacter pomeroyi
71c3t4cD_



not modelled 59.3 14 PDB header:transferase
Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria
72d1hdoa_



not modelled 59.1 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
73d1pvda1



not modelled 59.0 17 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
74c3glsC_



not modelled 58.7 29 PDB header:hydrolase
Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3,
PDBTitle: crystal structure of human sirt3
75c3k35D_



not modelled 58.5 29 PDB header:hydrolase
Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6;
PDBTitle: crystal structure of human sirt6
76c2an1D_



not modelled 58.1 23 PDB header:transferase
Chain: D: PDB Molecule:putative kinase;
PDBTitle: structural genomics, the crystal structure of a putative kinase from2 salmonella typhimurim lt2
77c2fw9A_



not modelled 58.1 17 PDB header:lyase
Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase;
PDBTitle: structure of pure (n5-carboxyaminoimidazole ribonucleotide mutase)2 h59f from the acidophilic bacterium acetobacter aceti, at ph 8
78d1j8fa_



not modelled 58.1 36 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
79c3orsD_



not modelled 57.7 15 PDB header:isomerase,biosynthetic protein
Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus
80d1t9ba1



not modelled 57.4 23 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
81c3eqzB_



not modelled 57.2 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:response regulator;
PDBTitle: crystal structure of a response regulator from colwellia2 psychrerythraea
82d1o4va_



not modelled 57.1 16 Fold:Flavodoxin-like
Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
83d1m2ka_



not modelled 57.1 29 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Sir2 family of transcriptional regulators
84d1rlia_



not modelled 57.0 15 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Hypothetical protein YwqN
85c1k97A_



not modelled 56.7 27 PDB header:ligase
Chain: A: PDB Molecule:argininosuccinate synthase;
PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline
86d1qcza_



not modelled 56.3 17 Fold:Flavodoxin-like
Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)
87c2yxbA_



not modelled 56.1 8 PDB header:isomerase
Chain: A: PDB Molecule:coenzyme b12-dependent mutase;
PDBTitle: crystal structure of the methylmalonyl-coa mutase alpha-subunit from2 aeropyrum pernix
88d1iowa1



not modelled 56.0 15 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:D-Alanine ligase N-terminal domain
89c3sz8D_



not modelled 55.9 23 PDB header:transferase
Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei
90d1gpja2



not modelled 55.7 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
91c3lp6D_



not modelled 55.5 20 PDB header:lyase
Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit;
PDBTitle: crystal structure of rv3275c-e60a from mycobacterium tuberculosis at2 1.7a resolution
92c3zquA_



not modelled 55.4 17 PDB header:lyase
Chain: A: PDB Molecule:probable aromatic acid decarboxylase;
PDBTitle: structure of a probable aromatic acid decarboxylase
93c3i2vA_



not modelled 54.0 20 PDB header:transferase
Chain: A: PDB Molecule:adenylyltransferase and sulfurtransferase mocs3;
PDBTitle: crystal structure of human mocs3 rhodanese-like domain
94d2vvpa1



not modelled 53.8 11 Fold:Ribose/Galactose isomerase RpiB/AlsB
Superfamily:Ribose/Galactose isomerase RpiB/AlsB
Family:Ribose/Galactose isomerase RpiB/AlsB
95c3fs2A_



not modelled 53.5 14 PDB header:transferase
Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution
96d1b1ca_



not modelled 53.3 16 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Cytochrome p450 reductase N-terminal domain-like
97c2ywxA_



not modelled 53.2 19 PDB header:lyase
Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit;
PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase2 catalytic subunit from methanocaldococcus jannaschii
98d2djia1



not modelled 52.8 31 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
99c3r74B_



not modelled 52.8 19 PDB header:lyase, biosynthetic protein
Chain: B: PDB Molecule:anthranilate/para-aminobenzoate synthases component i;
PDBTitle: crystal structure of 2-amino-2-desoxyisochorismate synthase (adic)2 synthase phze from burkholderia lata 383
100d1tlla2



not modelled 52.5 9 Fold:Flavodoxin-like
Superfamily:Flavoproteins
Family:Cytochrome p450 reductase N-terminal domain-like
101c3k7pA_



not modelled 52.3 22 PDB header:isomerase
Chain: A: PDB Molecule:ribose 5-phosphate isomerase;
PDBTitle: structure of mutant of ribose 5-phosphate isomerase type b from2 trypanosoma cruzi.
102c3m1pA_



not modelled 52.3 22 PDB header:isomerase
Chain: A: PDB Molecule:ribose 5-phosphate isomerase;
PDBTitle: structure of ribose 5-phosphate isomerase type b from trypanosoma2 cruzi, soaked with allose-6-phosphate
103c1wv9B_



not modelled 51.9 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:rhodanese homolog tt1651;
PDBTitle: crystal structure of rhodanese homolog tt1651 from an2 extremely thermophilic bacterium thermus thermophilus hb8
104c3lvuB_



not modelled 51.6 10 PDB header:transport protein
Chain: B: PDB Molecule:abc transporter, periplasmic substrate-binding protein;
PDBTitle: crystal structure of abc transporter, periplasmic substrate-binding2 protein spo2066 from silicibacter pomeroyi
105c2gcgB_



not modelled 51.5 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate reductase/hydroxypyruvate reductase;
PDBTitle: ternary crystal structure of human glyoxylate2 reductase/hydroxypyruvate reductase
106d2ez9a1



not modelled 51.2 25 Fold:DHS-like NAD/FAD-binding domain
Superfamily:DHS-like NAD/FAD-binding domain
Family:Pyruvate oxidase and decarboxylase, middle domain
107c3s5pA_



not modelled 50.7 33 PDB header:isomerase
Chain: A: PDB Molecule:ribose 5-phosphate isomerase;
PDBTitle: crystal structure of ribose-5-phosphate isomerase b rpib from giardia2 lamblia
108c3he8A_



not modelled 50.3 22 PDB header:isomerase
Chain: A: PDB Molecule:ribose-5-phosphate isomerase;
PDBTitle: structural study of clostridium thermocellum ribose-5-phosphate2 isomerase b
109c1y80A_



not modelled 49.6 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:predicted cobalamin binding protein;
PDBTitle: structure of a corrinoid (factor iiim)-binding protein from2 moorella thermoacetica
110c2axqA_



not modelled 49.5 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
111c3a2kB_



not modelled 49.3 14 PDB header:ligase/rna
Chain: B: PDB Molecule:trna(ile)-lysidine synthase;
PDBTitle: crystal structure of tils complexed with trna
112c3dzcA_



not modelled 49.2 3 PDB header:isomerase
Chain: A: PDB Molecule:udp-n-acetylglucosamine 2-epimerase;
PDBTitle: 2.35 angstrom resolution structure of wecb (vc0917), a udp-n-2 acetylglucosamine 2-epimerase from vibrio cholerae.
113c3pkiF_



not modelled 49.1 29 PDB header:hydrolase
Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6;
PDBTitle: human sirt6 crystal structure in complex with adp ribose
114c3g5jA_



not modelled 49.1 9 PDB header:nucleotide binding protein
Chain: A: PDB Molecule:putative atp/gtp binding protein;
PDBTitle: crystal structure of n-terminal domain of putative atp/gtp binding2 protein from clostridium difficile 630
115c2ejsA_



not modelled 49.1 17 PDB header:ligase
Chain: A: PDB Molecule:autocrine motility factor receptor, isoform 2;
PDBTitle: solution structure of ruh-076, a human cue domain
116c2pgnA_



not modelled 49.0 32 PDB header:hydrolase
Chain: A: PDB Molecule:cyclohexane-1,2-dione hydrolase (cdh);
PDBTitle: the crystal structure of fad and thdp-dependent cyclohexane-1,2-dione2 hydrolase in complex with cyclohexane-1,2-dione
117d1g8aa_



not modelled 49.0 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
118c3b2nA_



not modelled 48.8 17 PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein q99uf4;
PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus
119c3trhI_



not modelled 48.5 12 PDB header:lyase
Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase
PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii
120c2ejbA_



not modelled 48.5 18 PDB header:lyase
Chain: A: PDB Molecule:probable aromatic acid decarboxylase;
PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0