Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	P	Q	L	L	R	V	T	N	R	I	I	E	R	S	R	E	T	R	S	A	Y	L	A	R	I	E	Q	A	K	T	S	T	V	H	R	S	Q	L	A	C	G	N	L	A	H	G	F	A	A	C	Q	P	E	D	K	A	S	L
Secondary structure
SS confidence
Disorder		?	?	?													?	?												?	?	?	?	?		?	?		?													?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	S	M	L	R	N	N	I	A	I	I	T	S	Y	N	D	M	L	S	A	H	Q	P	Y	E	H	Y	P	E	I	I	R	K	A	L	H	E	A	N	A	V	G	Q	V	A	G	G	V	P	A	M	C	D	G	V	T	Q	G	Q	D
Secondary structure
SS confidence
Disorder																																																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	M	E	L	S	L	L	S	R	E	V	I	A	M	S	A	A	V	G	L	S	H	N	M	F	D	G	A	L	F	L	G	V	C	D	K	I	V	P	G	L	T	M	A	A	L	S	F	G	H	L	P	A	V	F	V	P	S	G	P
Secondary structure
SS confidence
Disorder																																																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		M	A	S	G	L	P	N	K	E	K	V	R	I	R	Q	L	Y	A	E	G	K	V	D	R	M	A	L	L	E	S	E	A	A	S	Y	H	A	P	G	T	C	T	F	Y	G	T	A	N	T	N	Q	M	V	V	E	F	M	G	M	Q
Secondary structure
SS confidence
Disorder				?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	P	G	S	S	F	V	H	P	D	S	P	L	R	D	A	L	T	A	A	A	A	R	Q	V	T	R	M	T	G	N	G	N	E	W	M	P	I	G	K	M	I	D	E	K	V	V	V	N	G	I	V	A	L	L	A	T	G	G	S
Secondary structure
SS confidence
Disorder										?																							?	?	?									?					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		T	N	H	T	M	H	L	V	A	M	A	R	A	A	G	I	Q	I	N	W	D	D	F	S	D	L	S	D	V	V	P	L	M	A	R	L	Y	P	N	G	P	A	D	I	N	H	F	Q	A	A	G	G	V	P	V	L	V	R	E	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	K	A	G	L	L	H	E	D	V	N	T	V	A	G	F	G	L	S	R	Y	T	L	E	P	W	L	N	N	G	E	L	D	W	R	E	G	A	E	K	S	L	D	S	N	V	I	A	S	F	E	Q	P	F	S	H	H	G	G	T
Secondary structure
SS confidence
Disorder																													?		?	?	?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		K	V	L	S	G	N	L	G	R	A	V	M	K	T	S	A	V	P	V	E	N	Q	V	I	E	A	P	A	V	V	F	E	S	Q	H	D	V	M	P	A	F	E	A	G	L	L	D	R	D	C	V	V	V	V	R	H	Q	G	P	K
Secondary structure
SS confidence
Disorder																				?	?																							?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		A	N	G	M	P	E	L	H	K	L	M	P	P	L	G	V	L	L	D	R	C	F	K	I	A	L	V	T	D	G	R	L	S	G	A	S	G	K	V	P	S	A	I	H	V	T	P	E	A	Y	D	G	G	L	L	A	K	V	R	D
Secondary structure
SS confidence
Disorder			?		?	?	?	?	?	?	?	?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		G	D	I	I	R	V	N	G	Q	T	G	E	L	T	L	L	V	D	E	A	E	L	A	A	R	E	P	H	I	P	D	L	S	A	S	R	V	G	T	G	R	E	L	F	S	A	L	R	E	K	L	S	G	A	E	Q	G	A	T	C
Secondary structure
SS confidence
Disorder																														?	?	?		?	?	?	?	?	?	?												?	?								?
Disorder confidence
		.	.	.
Sequence		I	T	F
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gp4 chain A Region: 2 - 600 Aligned: 513 Modelled: 515 Confidence: 100.0% Identity: 65% PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis Phyre2 PDB 2gp4 chain A domain 2 Region: 2 - 418 Aligned: 330 Modelled: 339 Confidence: 100.0% Identity: 65% Fold: IlvD/EDD N-terminal domain-like Superfamily: IlvD/EDD N-terminal domain-like Family: lvD/EDD N-terminal domain-like Phyre2 PDB 2gp4 chain A domain 1 Region: 419 - 600 Aligned: 182 Modelled: 182 Confidence: 100.0% Identity: 63% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: IlvD/EDD C-terminal domain-like Phyre2 PDB 1zym chain A domain 2 Region: 435 - 573 Aligned: 115 Modelled: 126 Confidence: 92.4% Identity: 15% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system Phyre2 PDB 1vbg chain A domain 2 Region: 443 - 553 Aligned: 85 Modelled: 96 Confidence: 86.8% Identity: 22% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: Pyruvate phosphate dikinase, central domain Phyre2 PDB 1vi4 chain A Region: 442 - 512 Aligned: 64 Modelled: 65 Confidence: 77.0% Identity: 13% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 1h6z chain A domain 2 Region: 443 - 553 Aligned: 86 Modelled: 96 Confidence: 75.2% Identity: 21% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: Pyruvate phosphate dikinase, central domain Phyre2 PDB 2pcn chain A Region: 447 - 511 Aligned: 58 Modelled: 65 Confidence: 70.6% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine:2-demethylmenaquinone PDBTitle: crystal structure of s-adenosylmethionine: 2-dimethylmenaquinone2 methyltransferase (gk_1813) from geobacillus kaustophilus hta426 Phyre2 PDB 1eza chain A Region: 516 - 568 Aligned: 47 Modelled: 53 Confidence: 68.7% Identity: 13% PDB header:phosphotransferase Chain: A: PDB Molecule:enzyme i; PDBTitle: amino terminal domain of enzyme i from escherichia coli nmr,2 restrained regularized mean structure Phyre2 PDB 1q5x chain A Region: 442 - 512 Aligned: 64 Modelled: 67 Confidence: 66.0% Identity: 20% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 3l83 chain A Region: 135 - 238 Aligned: 82 Modelled: 104 Confidence: 64.5% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:glutamine amido transferase; PDBTitle: crystal structure of glutamine amido transferase from methylobacillus2 flagellatus Phyre2 PDB 2jv2 chain A Region: 538 - 557 Aligned: 20 Modelled: 20 Confidence: 58.3% Identity: 35% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein ph1500; PDBTitle: solution structure of the n-terminal domain of ph1500 Phyre2 PDB 1nxj chain A Region: 447 - 511 Aligned: 58 Modelled: 65 Confidence: 57.8% Identity: 12% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 1nxj chain A Region: 447 - 511 Aligned: 58 Modelled: 60 Confidence: 57.8% Identity: 12% PDB header:unknown function Chain: A: PDB Molecule:probable s-adenosylmethionine:2- PDBTitle: structure of rv3853 from mycobacterium tuberculosis Phyre2 PDB 2hwg chain A Region: 516 - 568 Aligned: 47 Modelled: 49 Confidence: 57.7% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of phosphorylated enzyme i of the2 phosphoenolpyruvate:sugar phosphotransferase system Phyre2 PDB 3c8o chain B Region: 447 - 511 Aligned: 58 Modelled: 65 Confidence: 57.0% Identity: 17% PDB header:hydrolase regulator Chain: B: PDB Molecule:regulator of ribonuclease activity a; PDBTitle: the crystal structure of rraa from pao1 Phyre2 PDB 2hi6 chain A domain 1 Region: 538 - 556 Aligned: 19 Modelled: 19 Confidence: 49.3% Identity: 37% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: AF0055-like Phyre2 PDB 1j3l chain A Region: 447 - 511 Aligned: 58 Modelled: 59 Confidence: 45.5% Identity: 19% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 3nxk chain E Region: 65 - 188 Aligned: 111 Modelled: 124 Confidence: 43.8% Identity: 11% PDB header:hydrolase Chain: E: PDB Molecule:cytoplasmic l-asparaginase; PDBTitle: crystal structure of probable cytoplasmic l-asparaginase from2 campylobacter jejuni Phyre2 PDB 1a9x chain B domain 2 Region: 165 - 241 Aligned: 55 Modelled: 63 Confidence: 43.2% Identity: 16% Fold: Flavodoxin-like Superfamily: Class I glutamine amidotransferase-like Family: Class I glutamine amidotransferases (GAT) Phyre2 1 c2gp4A_ 2 d2gp4a2 3 d2gp4a1 4 d1zyma2 5 d1vbga2 6 d1vi4a_ 7 d1h6za2 8 c2pcnA_ 9 c1ezaA_ 10 d1q5xa_ 11 c3l83A_ 12 c2jv2A_ 13 d1nxja_ 14 c1nxjA_ 15 c2hwgA_ 16 c3c8oB_ 17 d2hi6a1 18 d1j3la_ 19 c3nxkE_ 20 d1a9xb2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99