Email l.a.kelley@imperial.ac.uk Description P76245 Date Thu Jan 5 12:21:11 GMT 2012 Unique Job ID 156713ed3463e27e

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1w25B_ 100.0 28 PDB header:signaling protein Chain: B: PDB Molecule:stalked-cell differentiation controlling protein; PDBTitle: response regulator pled in complex with c-digmp 2 c3ezuA_ 100.0 28 PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution 3 c3breA_ 100.0 27 PDB header:signaling protein Chain: A: PDB Molecule:probable two-component response regulator; PDBTitle: crystal structure of p.aeruginosa pa3702 4 c3iclA_ 100.0 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:eal/ggdef domain protein; PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium3 target mcr174c 5 c3ignA_ 100.0 24 PDB header:transferase Chain: A: PDB Molecule:diguanylate cyclase; PDBTitle: crystal structure of the ggdef domain from marinobacter2 aquaeolei diguanylate cyclase complexed with c-di-gmp -3 northeast structural genomics consortium target mqr89a 6 c3i5aA_ 100.0 28 PDB header:signaling protein Chain: A: PDB Molecule:response regulator/ggdef domain protein; PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae 7 c3hvaA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx ggdef domain from pseudomonas2 aeruginosa 8 c3i5bA_ 100.0 24 PDB header:signaling protein Chain: A: PDB Molecule:wspr response regulator; PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa 9 d1w25a3 100.0 30 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:GGDEF domain 10 c3i5cA_ 100.0 27 PDB header:signaling protein Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa 11 c3mtkA_ 100.0 21 PDB header:transferase Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase; PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c 12 c3qyyB_ 100.0 29 PDB header:signaling protein/inhibitor Chain: B: PDB Molecule:response regulator; PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp 13 c3hvwA_ 100.0 13 PDB header:lyase Chain: A: PDB Molecule:diguanylate-cyclase (dgc); PDBTitle: crystal structure of the ggdef domain of the pa2567 protein2 from pseudomonas aeruginosa, northeast structural genomics3 consortium target par365c 14 c3pjwA_ 100.0 22 PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 15 c3gfzB_ 99.7 10 PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex 16 c3ci6B_ 99.1 11 PDB header:transferase Chain: B: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: crystal structure of the gaf domain from acinetobacter2 phosphoenolpyruvate-protein phosphotransferase 17 c3trcA_ 99.0 14 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of the gaf domain from a phosphoenolpyruvate-protein2 phosphotransferase (ptsp) from coxiella burnetii 18 d2o9ca1 99.0 16 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 19 c3k2nB_ 99.0 18 PDB header:transcription regulator Chain: B: PDB Molecule:sigma-54-dependent transcriptional regulator; PDBTitle: the crystal structure of sigma-54-dependent transcriptional2 regulator domain from chlorobium tepidum tls 20 c3mmhA_ 98.9 14 PDB header:oxidoreductase Chain: A: PDB Molecule:methionine-r-sulfoxide reductase; PDBTitle: x-ray structure of free methionine-r-sulfoxide reductase from2 neisseria meningitidis in complex with its substrate 21 c2zmfA_ 98.9 11 PDB header:hydrolase Chain: A: PDB Molecule:camp and camp-inhibited cgmp 3',5'-cyclic phosphodiesterase PDBTitle: crystal structure of the c-terminal gaf domain of human2 phosphodiesterase 10a 22 d2veaa1 not modelled 98.9 14 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 23 c3p7nB_ not modelled 98.9 13 PDB header:dna binding protein Chain: B: PDB Molecule:sensor histidine kinase; PDBTitle: crystal structure of light activated transcription factor el222 from2 erythrobacter litoralis 24 d2oola1 not modelled 98.8 16 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 25 c3oovA_ not modelled 98.8 13 PDB header:signaling protein Chain: A: PDB Molecule:methyl-accepting chemotaxis protein, putative; PDBTitle: crystal structure of a methyl-accepting chemotaxis protein, residues2 122 to 287 26 c3p01C_ not modelled 98.7 12 PDB header:signaling protein Chain: C: PDB Molecule:two-component response regulator; PDBTitle: crystal structure of two-component response regulator from nostoc sp.2 pcc 7120 27 c3o5yA_ not modelled 98.7 14 PDB header:transcription regulator Chain: A: PDB Molecule:sensor protein; PDBTitle: the crystal structure of the gaf domain of a two-component sensor2 histidine kinase from bacillus halodurans to 2.45a 28 c2qybA_ not modelled 98.7 16 PDB header:membrane protein Chain: A: PDB Molecule:membrane protein, putative; PDBTitle: crystal structure of the gaf domain region of putative membrane2 protein from geobacter sulfurreducens pca 29 c3p01A_ not modelled 98.7 11 PDB header:signaling protein Chain: A: PDB Molecule:two-component response regulator; PDBTitle: crystal structure of two-component response regulator from nostoc sp.2 pcc 7120 30 d3c2wa1 not modelled 98.6 15 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 31 c1vhmB_ not modelled 98.6 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein yebr; PDBTitle: crystal structure of an hypothetical protein 32 c3eeaB_ not modelled 98.6 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:gaf domain/hd domain protein; PDBTitle: the crystal structure of the gaf domain/hd domain protein2 from geobacter sulfurreducens 33 c3ibjB_ not modelled 98.6 11 PDB header:hydrolase Chain: B: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase; PDBTitle: x-ray structure of pde2a 34 d1vhma_ not modelled 98.5 12 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 35 c1mc0A_ not modelled 98.5 9 PDB header:hydrolase Chain: A: PDB Molecule:3',5'-cyclic nucleotide phosphodiesterase 2a; PDBTitle: regulatory segment of mouse 3',5'-cyclic nucleotide phosphodiesterase2 2a, containing the gaf a and gaf b domains 36 d1mc0a1 not modelled 98.5 12 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 37 c3hcyB_ not modelled 98.5 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative two-component sensor histidine kinase protein; PDBTitle: the crystal structure of the domain of putative two-component sensor2 histidine kinase protein from sinorhizobium meliloti 1021 38 c2vjwA_ not modelled 98.5 13 PDB header:hydrolase Chain: A: PDB Molecule:gaf family protein; PDBTitle: crystal structure of the second gaf domain of devs from2 mycobacterium smegmatis 39 c3ksiA_ not modelled 98.4 10 PDB header:oxidoreductase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: structure of frmsr of staphylococcus aureus (complex with 2-propanol) 40 c3e0yA_ not modelled 98.4 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved domain protein; PDBTitle: the crystal structure of a conserved domain from a protein of2 geobacter sulfurreducens pca 41 c3dbaB_ not modelled 98.4 11 PDB header:hydrolase Chain: B: PDB Molecule:cone cgmp-specific 3',5'-cyclic phosphodiesterase subunit PDBTitle: crystal structure of the cgmp-bound gaf a domain from the2 photoreceptor phosphodiesterase 6c 42 c2w3gA_ not modelled 98.3 14 PDB header:transferase Chain: A: PDB Molecule:two component sensor histidine kinase devs (gaf PDBTitle: air-oxidized structure of the first gaf domain of2 mycobacterium tuberculosis doss 43 d2k2na1 not modelled 98.3 19 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 44 c2lb5A_ not modelled 98.3 16 PDB header:transferase Chain: A: PDB Molecule:sensor histidine kinase; PDBTitle: refined structural basis for the photoconversion of a phytochrome to2 the activated far-red light-absorbing form 45 d1mc0a2 not modelled 98.2 10 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 46 c3mf0A_ not modelled 98.2 8 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: crystal structure of pde5a gaf domain (89-518) 47 c1ykdB_ not modelled 98.2 10 PDB header:lyase Chain: B: PDB Molecule:adenylate cyclase; PDBTitle: crystal structure of the tandem gaf domains from a cyanobacterial2 adenylyl cyclase: novel modes of ligand-binding and dimerization 48 c3e98B_ not modelled 98.1 12 PDB header:unknown function Chain: B: PDB Molecule:gaf domain of unknown function; PDBTitle: crystal structure of a gaf domain containing protein that belongs to2 pfam duf484 family (pa5279) from pseudomonas aeruginosa at 2.43 a3 resolution 49 c2oolA_ not modelled 98.1 16 PDB header:signaling protein Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of the chromophore-binding domain of an unusual2 bacteriophytochrome rpbphp3 from r. palustris 50 c3c2wB_ not modelled 98.0 13 PDB header:signaling protein Chain: B: PDB Molecule:bacteriophytochrome; PDBTitle: crystal structure of the photosensory core domain of p.2 aeruginosa bacteriophytochrome pabphp in the pfr state 51 c2k31A_ not modelled 98.0 11 PDB header:hydrolase Chain: A: PDB Molecule:phosphodiesterase 5a, cgmp-specific; PDBTitle: solution structure of cgmp-binding gaf domain of2 phosphodiesterase 5 52 c2o9bA_ not modelled 97.9 16 PDB header:transferase Chain: A: PDB Molecule:bacteriophytochrome; PDBTitle: crystal structure of bacteriophytochrome chromophore binding domain 53 c2qv6D_ not modelled 97.7 21 PDB header:hydrolase Chain: D: PDB Molecule:gtp cyclohydrolase iii; PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions 54 d1f5ma_ not modelled 97.5 10 Fold:Profilin-like Superfamily:GAF domain-like Family:GAF domain 55 c2veaA_ not modelled 97.5 13 PDB header:transferase Chain: A: PDB Molecule:phytochrome-like protein cph1; PDBTitle: the complete sensory module of the cyanobacterial2 phytochrome cph1 in the pr-state. 56 c2xssB_ not modelled 97.2 10 PDB header:hydrolase Chain: B: PDB Molecule:cgmp-specific 3', 5'-cyclic phosphodiesterase; PDBTitle: crystal structure of gafb from the human phosphodiesterase 5 57 d1azsa_ not modelled 89.9 15 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 58 d1fx2a_ not modelled 89.0 12 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 59 c2aq4A_ not modelled 87.3 21 PDB header:transferase Chain: A: PDB Molecule:dna repair protein rev1; PDBTitle: ternary complex of the catalytic core of rev1 with dna and dctp. 60 c1cjkA_ not modelled 86.4 17 PDB header:lyase/lyase/signaling protein Chain: A: PDB Molecule:adenylate cyclase, type v; PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn 61 c1ybuA_ not modelled 84.9 16 PDB header:hydrolase Chain: A: PDB Molecule:lipj; PDBTitle: mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex2 with a substrate analog. 62 d1fx4a_ not modelled 84.2 16 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 63 c1wc6B_ not modelled 84.2 17 PDB header:lyase Chain: B: PDB Molecule:adenylate cyclase; PDBTitle: soluble adenylyl cyclase cyac from s. platensis in complex2 with rp-atpalphas in presence of bicarbonate 64 d1wc1a_ not modelled 83.6 16 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 65 c3mr7B_ not modelled 81.1 16 PDB header:hydrolase Chain: B: PDB Molecule:adenylate/guanylate cyclase/hydrolase, alpha/beta fold PDBTitle: crystal structure of adenylate/guanylate cyclase/hydrolase from2 silicibacter pomeroyi 66 c3et6A_ not modelled 80.9 11 PDB header:lyase Chain: A: PDB Molecule:soluble guanylyl cyclase beta; PDBTitle: the crystal structure of the catalytic domain of a eukaryotic2 guanylate cyclase 67 c2w01C_ not modelled 76.5 16 PDB header:lyase Chain: C: PDB Molecule:adenylate cyclase; PDBTitle: crystal structure of the guanylyl cyclase cya2 68 c1yk9A_ not modelled 72.7 13 PDB header:lyase Chain: A: PDB Molecule:adenylate cyclase; PDBTitle: crystal structure of a mutant form of the mycobacterial2 adenylyl cyclase rv1625c 69 c3gqcB_ not modelled 71.8 21 PDB header:transferase/dna Chain: B: PDB Molecule:dna repair protein rev1; PDBTitle: structure of human rev1-dna-dntp ternary complex 70 c1y10C_ not modelled 71.4 11 PDB header:lyase Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302; PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state 71 c3uvjC_ not modelled 69.0 14 PDB header:lyase Chain: C: PDB Molecule:guanylate cyclase soluble subunit alpha-3; PDBTitle: crystal structure of the catalytic domain of the heterodimeric human2 soluble guanylate cyclase 1. 72 c2gx5B_ not modelled 65.9 11 PDB header:transcription Chain: B: PDB Molecule:gtp-sensing transcriptional pleiotropic repressor cody; PDBTitle: n-terminal gaf domain of transcriptional pleiotropic repressor cody 73 c1s97D_ not modelled 61.6 17 PDB header:transferase/dna Chain: D: PDB Molecule:dna polymerase iv; PDBTitle: dpo4 with gt mismatch 74 c3onqB_ not modelled 58.5 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:regulator of polyketide synthase expression; PDBTitle: crystal structure of regulator of polyketide synthase expression2 bad_0249 from bifidobacterium adolescentis 75 c1k1qA_ not modelled 51.4 20 PDB header:transcription Chain: A: PDB Molecule:dbh protein; PDBTitle: crystal structure of a dinb family error prone dna2 polymerase from sulfolobus solfataricus 76 c3r5gB_ not modelled 50.7 12 PDB header:lyase Chain: B: PDB Molecule:cyab; PDBTitle: crystal structure of the adenylyl cyclase cyab from p. aeruginosa 77 c2r8kB_ not modelled 50.2 29 PDB header:replication, transferase/dna Chain: B: PDB Molecule:dna polymerase eta; PDBTitle: structure of the eukaryotic dna polymerase eta in complex with 1,2-2 d(gpg)-cisplatin containing dna 78 c3cloC_ not modelled 49.2 12 PDB header:transcription regulator Chain: C: PDB Molecule:transcriptional regulator; PDBTitle: crystal structure of putative transcriptional regulator containing a2 luxr dna binding domain (np_811094.1) from bacteroides3 thetaiotaomicron vpi-5482 at 2.04 a resolution 79 c1jihA_ not modelled 47.0 29 PDB header:translation Chain: A: PDB Molecule:dna polymerase eta; PDBTitle: yeast dna polymerase eta 80 d1l3la2 not modelled 40.3 15 Fold:Profilin-like Superfamily:Pheromone-binding domain of LuxR-like quorum-sensing transcription factors Family:Pheromone-binding domain of LuxR-like quorum-sensing transcription factors 81 c3bwlA_ not modelled 39.7 9 PDB header:transferase Chain: A: PDB Molecule:sensor protein; PDBTitle: crystal structure of pas domain of htr-like protein from haloarcula2 marismortui 82 c3mfxA_ not modelled 35.0 7 PDB header:transcription Chain: A: PDB Molecule:sensory box/ggdef family protein; PDBTitle: crystal structure of the sensory box domain of the sensory-2 box/ggdef protein so_1695 from shewanella oneidensis,3 northeast structural genomics consortium target sor288b 83 c3mxqC_ not modelled 35.0 13 PDB header:transferase Chain: C: PDB Molecule:sensor protein; PDBTitle: crystal structure of sensory box sensor histidine kinase from vibrio2 cholerae 84 d1jx4a2 not modelled 33.0 15 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Lesion bypass DNA polymerase (Y-family), catalytic domain 85 c2wz1B_ not modelled 31.7 14 PDB header:lyase Chain: B: PDB Molecule:guanylate cyclase soluble subunit beta-1; PDBTitle: structure of the catalytic domain of human soluble2 guanylate cyclase 1 beta 3. 86 c2oh2B_ not modelled 31.6 21 PDB header:transferase/dna Chain: B: PDB Molecule:dna polymerase kappa; PDBTitle: ternary complex of human dna polymerase 87 d1im4a_ not modelled 30.0 20 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Lesion bypass DNA polymerase (Y-family), catalytic domain 88 c2qkpD_ not modelled 30.0 12 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of c-terminal domain of smu_1151c from streptococcus2 mutans 89 c2w0nA_ not modelled 28.7 10 PDB header:transferase Chain: A: PDB Molecule:sensor protein dcus; PDBTitle: plasticity of pas domain and potential role for signal2 transduction in the histidine-kinase dcus 90 c3mr2A_ not modelled 28.5 25 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase eta; PDBTitle: human dna polymerase eta in complex with normal dna and incoming2 nucleotide (nrm) 91 d1ew0a_ not modelled 26.5 17 Fold:Profilin-like Superfamily:PYP-like sensor domain (PAS domain) Family:Heme-binding PAS domain 92 c2w1rA_ not modelled 24.9 12 PDB header:transcription Chain: A: PDB Molecule:stage v sporulation protein t; PDBTitle: crystal structure of the c-terminal domain of b. subtilis2 spovt 93 d1jiha2 not modelled 23.9 20 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Lesion bypass DNA polymerase (Y-family), catalytic domain 94 d1t0aa_ not modelled 23.5 13 Fold:Bacillus chorismate mutase-like Superfamily:IpsF-like Family:IpsF-like 95 c3lyxA_ not modelled 22.8 12 PDB header:transcription Chain: A: PDB Molecule:sensory box/ggdef domain protein; PDBTitle: crystal structure of the pas domain of the protein cps_12912 from colwellia psychrerythraea. northeast structural3 genomics consortium target id csr222b 96 c3oloB_ not modelled 21.2 9 PDB header:transferase Chain: B: PDB Molecule:two-component sensor histidine kinase; PDBTitle: crystal structure of a pas domain from two-component sensor histidine2 kinase 97 d1azsb_ not modelled 21.1 11 Fold:Ferredoxin-like Superfamily:Nucleotide cyclase Family:Adenylyl and guanylyl cyclase catalytic domain 98 d1w55a2 not modelled 20.8 9 Fold:Bacillus chorismate mutase-like Superfamily:IpsF-like Family:IpsF-like 99 d1iv3a_ not modelled 18.6 14 Fold:Bacillus chorismate mutase-like Superfamily:IpsF-like Family:IpsF-like