Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	L	T	L	N	R	Q	L	L	T	S	R	Q	I	L	V	A	F	S	G	G	L	D	S	T	V	L	L	H	Q	L	V	Q	W	R	T	E	N	P	G	V	A	L	R	A	I	H	V	H	H	G	L	S	A	N	A	D	A	W
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	T	H	C	E	N	V	C	Q	Q	W	Q	V	P	L	V	V	E	R	V	Q	L	A	Q	E	G	L	G	I	E	A	Q	A	R	Q	A	R	Y	Q	A	F	A	R	T	L	L	P	G	E	V	L	V	T	A	Q	H	L	D	D	Q
Secondary structure
SS confidence
Disorder																								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		C	E	T	F	L	L	A	L	K	R	G	S	G	P	A	G	L	S	A	M	A	E	V	S	E	F	A	G	T	R	L	I	R	P	L	L	A	R	T	R	G	E	L	V	Q	W	A	R	Q	Y	D	L	R	W	I	E	D	E	S	N
Secondary structure
SS confidence
Disorder																		?					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Q	D	D	S	Y	D	R	N	F	L	R	L	R	V	V	P	L	L	Q	Q	R	W	P	H	F	A	E	A	T	A	R	S	A	A	L	C	A	E	Q	E	S	L	L	D	E	L	L	A	D	D	L	A	H	C	Q	S	P	Q	G	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	Q	I	V	P	M	L	A	M	S	D	A	R	R	A	A	I	I	R	R	W	L	A	G	Q	N	A	P	M	P	S	R	D	A	L	V	R	I	W	Q	E	V	A	L	A	R	E	D	A	S	P	C	L	R	L	G	A	F	E	I
Secondary structure
SS confidence
Disorder																										?	?	?	?	?	?															?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	R	Y	Q	S	Q	L	W	W	I	K	S	V	T	G	Q	S	E	N	I	V	P	W	Q	T	W	L	Q	P	L	E	L	P	A	G	L	G	S	V	Q	L	N	A	G	G	D	I	R	P	P	R	A	D	E	A	V	S	V	R	F
Secondary structure
SS confidence
Disorder															?	?	?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		K	A	P	G	L	L	H	I	V	G	R	N	G	G	R	K	L	K	K	I	W	Q	E	L	G	V	P	P	W	L	R	D	T	T	P	L	L	F	Y	G	E	T	L	I	A	A	A	G	V	F	V	T	Q	E	G	V	A	E	G	E
Secondary structure
SS confidence
Disorder												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.
Sequence		N	G	V	S	F	V	W	Q	K	T	L	S
Secondary structure
SS confidence
Disorder										?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ni5 chain A Region: 2 - 432 Aligned: 431 Modelled: 431 Confidence: 100.0% Identity: 99% PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli Phyre2 PDB 3a2k chain B Region: 2 - 428 Aligned: 425 Modelled: 427 Confidence: 100.0% Identity: 27% PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna Phyre2 PDB 2e21 chain A Region: 2 - 313 Aligned: 298 Modelled: 309 Confidence: 100.0% Identity: 24% PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. Phyre2 PDB 1ni5 chain A domain 1 Region: 2 - 226 Aligned: 225 Modelled: 225 Confidence: 100.0% Identity: 100% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: PP-loop ATPase Phyre2 PDB 1wy5 chain A domain 1 Region: 2 - 202 Aligned: 197 Modelled: 201 Confidence: 100.0% Identity: 30% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: PP-loop ATPase Phyre2 PDB 2nz2 chain A Region: 12 - 194 Aligned: 166 Modelled: 178 Confidence: 99.9% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline Phyre2 PDB 1vl2 chain C Region: 12 - 188 Aligned: 160 Modelled: 170 Confidence: 99.9% Identity: 18% PDB header:ligase Chain: C: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution Phyre2 PDB 3k32 chain D Region: 15 - 204 Aligned: 167 Modelled: 177 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: D: PDB Molecule:uncharacterized protein mj0690; PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm Phyre2 PDB 2c5s chain A domain 1 Region: 9 - 205 Aligned: 179 Modelled: 180 Confidence: 99.9% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ThiI-like Phyre2 PDB 1k97 chain A Region: 4 - 180 Aligned: 161 Modelled: 172 Confidence: 99.9% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline Phyre2 PDB 1kh2 chain D Region: 14 - 182 Aligned: 149 Modelled: 157 Confidence: 99.9% Identity: 19% PDB header:ligase Chain: D: PDB Molecule:argininosuccinate synthetase; PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp Phyre2 PDB 1vl2 chain A domain 1 Region: 12 - 173 Aligned: 146 Modelled: 157 Confidence: 99.9% Identity: 18% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 2dpl chain A Region: 2 - 196 Aligned: 185 Modelled: 188 Confidence: 99.8% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b; PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3 Phyre2 PDB 1j20 chain A domain 1 Region: 14 - 173 Aligned: 139 Modelled: 147 Confidence: 99.8% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1k92 chain A domain 1 Region: 2 - 179 Aligned: 161 Modelled: 173 Confidence: 99.8% Identity: 15% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 PDB 1ni5 chain A domain 3 Region: 315 - 432 Aligned: 118 Modelled: 118 Confidence: 99.8% Identity: 100% Fold: PheT/TilS domain Superfamily: PheT/TilS domain Family: tRNA-Ile-lysidine synthetase, TilS, C-terminal domain Phyre2 PDB 2c5s chain A Region: 9 - 200 Aligned: 171 Modelled: 175 Confidence: 99.8% Identity: 21% PDB header:rna-binding protein Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii; PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain Phyre2 PDB 2hma chain A Region: 10 - 185 Aligned: 171 Modelled: 171 Confidence: 99.8% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)- PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae Phyre2 PDB 2der chain A Region: 13 - 177 Aligned: 157 Modelled: 160 Confidence: 99.8% Identity: 15% PDB header:transferase/rna Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma; PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state Phyre2 PDB 1gpm chain A domain 1 Region: 2 - 174 Aligned: 146 Modelled: 147 Confidence: 99.8% Identity: 20% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: N-type ATP pyrophosphatases Phyre2 1 c1ni5A_ 2 c3a2kB_ 3 c2e21A_ 4 d1ni5a1 5 d1wy5a1 6 c2nz2A_ 7 c1vl2C_ 8 c3k32D_ 9 d2c5sa1 10 c1k97A_ 11 c1kh2D_ 12 d1vl2a1 13 c2dplA_ 14 d1j20a1 15 d1k92a1 16 d1ni5a3 17 c2c5sA_ 18 c2hmaA_ 19 c2derA_ 20 d1gpma1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1ni5A_ 100.0 99 PDB header:cell cycle Chain: A: PDB Molecule:putative cell cycle protein mesj; PDBTitle: structure of the mesj pp-atpase from escherichia coli 2 c3a2kB_ 100.0 27 PDB header:ligase/rna Chain: B: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils complexed with trna 3 c2e21A_ 100.0 24 PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils in a complex with amppnp from aquifex2 aeolicus. 4 d1ni5a1 100.0 100 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 5 d1wy5a1 100.0 30 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PP-loop ATPase 6 c2nz2A_ 99.9 17 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of human argininosuccinate synthase in complex with2 aspartate and citrulline 7 c1vl2C_ 99.9 18 PDB header:ligase Chain: C: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of argininosuccinate synthase (tm1780) from2 thermotoga maritima at 1.65 a resolution 8 c3k32D_ 99.9 17 PDB header:transferase Chain: D: PDB Molecule:uncharacterized protein mj0690; PDBTitle: the crystal structure of predicted subunit of trna2 methyltransferase from methanocaldococcus jannaschii dsm 9 d2c5sa1 99.9 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like 10 c1k97A_ 99.9 15 PDB header:ligase Chain: A: PDB Molecule:argininosuccinate synthase; PDBTitle: crystal structure of e. coli argininosuccinate synthetase in complex2 with aspartate and citrulline 11 c1kh2D_ 99.9 19 PDB header:ligase Chain: D: PDB Molecule:argininosuccinate synthetase; PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp 12 d1vl2a1 99.9 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 13 c2dplA_ 99.8 13 PDB header:ligase Chain: A: PDB Molecule:gmp synthase [glutamine-hydrolyzing] subunit b; PDBTitle: crystal structure of the gmp synthase from pyrococcus horikoshii ot3 14 d1j20a1 99.8 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 15 d1k92a1 99.8 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 16 d1ni5a3 99.8 100 Fold:PheT/TilS domain Superfamily:PheT/TilS domain Family:tRNA-Ile-lysidine synthetase, TilS, C-terminal domain 17 c2c5sA_ 99.8 21 PDB header:rna-binding protein Chain: A: PDB Molecule:probable thiamine biosynthesis protein thii; PDBTitle: crystal structure of bacillus anthracis thii, a trna-2 modifying enzyme containing the predicted rna-binding3 thump domain 18 c2hmaA_ 99.8 16 PDB header:transferase Chain: A: PDB Molecule:probable trna (5-methylaminomethyl-2-thiouridylate)- PDBTitle: the crystal structure of trna (5-methylaminomethyl-2-thiouridylate)-2 methyltransferase trmu from streptococcus pneumoniae 19 c2derA_ 99.8 15 PDB header:transferase/rna Chain: A: PDB Molecule:trna-specific 2-thiouridylase mnma; PDBTitle: cocrystal structure of an rna sulfuration enzyme mnma and2 trna-glu in the initial trna binding state 20 d1gpma1 99.8 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 21 d1sura_ not modelled 99.8 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like 22 c3tqiB_ not modelled 99.8 21 PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: structure of the gmp synthase (guaa) from coxiella burnetii 23 d1vbka1 not modelled 99.7 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ThiI-like 24 c3p52B_ not modelled 99.7 17 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: nh3-dependent nad synthetase from campylobacter jejuni subsp. jejuni2 nctc 11168 in complex with the nitrate ion 25 c2o8vA_ not modelled 99.7 16 PDB header:oxidoreductase Chain: A: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: paps reductase in a covalent complex with thioredoxin c35a 26 c3hj7A_ not modelled 99.7 21 PDB header:ligase Chain: A: PDB Molecule:trna(ile)-lysidine synthase; PDBTitle: crystal structure of tils c-terminal domain 27 c3bl5E_ not modelled 99.7 14 PDB header:hydrolase Chain: E: PDB Molecule:queuosine biosynthesis protein quec; PDBTitle: crystal structure of quec from bacillus subtilis: an enzyme2 involved in preq1 biosynthesis 28 c2goyC_ not modelled 99.7 17 PDB header:oxidoreductase Chain: C: PDB Molecule:adenosine phosphosulfate reductase; PDBTitle: crystal structure of assimilatory adenosine 5'-2 phosphosulfate reductase with bound aps 29 c2ywcC_ not modelled 99.6 25 PDB header:ligase Chain: C: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: crystal structure of gmp synthetase from thermus thermophilus in2 complex with xmp 30 d1xnga1 not modelled 99.6 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 31 d1zuna1 not modelled 99.6 12 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:PAPS reductase-like 32 c3fiuD_ not modelled 99.5 17 PDB header:ligase Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nmn synthetase from francisella tularensis 33 d2pg3a1 not modelled 99.5 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 34 c3uowB_ not modelled 99.5 18 PDB header:ligase Chain: B: PDB Molecule:gmp synthetase; PDBTitle: crystal structure of pf10_0123, a gmp synthetase from plasmodium2 falciparum 35 c2oq2B_ not modelled 99.5 14 PDB header:oxidoreductase Chain: B: PDB Molecule:phosphoadenosine phosphosulfate reductase; PDBTitle: crystal structure of yeast paps reductase with pap, a product complex 36 c2vxoB_ not modelled 99.5 19 PDB header:ligase Chain: B: PDB Molecule:gmp synthase [glutamine-hydrolyzing]; PDBTitle: human gmp synthetase in complex with xmp 37 c1zunA_ not modelled 99.5 13 PDB header:transferase Chain: A: PDB Molecule:sulfate adenylyltransferase subunit 2; PDBTitle: crystal structure of a gtp-regulated atp sulfurylase2 heterodimer from pseudomonas syringae 38 c1gpmD_ not modelled 99.5 18 PDB header:transferase (glutamine amidotransferase) Chain: D: PDB Molecule:gmp synthetase; PDBTitle: escherichia coli gmp synthetase complexed with amp and pyrophosphate 39 c2e18B_ not modelled 99.4 12 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of project ph0182 from pyrococcus horikoshii ot3 40 c3g59A_ not modelled 99.2 15 PDB header:transferase Chain: A: PDB Molecule:fmn adenylyltransferase; PDBTitle: crystal structure of candida glabrata fmn2 adenylyltransferase in complex with atp 41 c3q4gA_ not modelled 99.0 15 PDB header:ligase Chain: A: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nad synthetase from vibrio cholerae 42 c2wsiA_ not modelled 99.0 17 PDB header:transferase Chain: A: PDB Molecule:fad synthetase; PDBTitle: crystal structure of yeast fad synthetase (fad1) in complex2 with fad 43 d1kqpa_ not modelled 99.0 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 44 c3dpiA_ not modelled 98.9 19 PDB header:ligase Chain: A: PDB Molecule:nad+ synthetase; PDBTitle: crystal structure of nad+ synthetase from burkholderia pseudomallei 45 c1vbkA_ not modelled 98.9 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ph1313; PDBTitle: crystal structure of ph1313 from pyrococcus horikoshii ot3 46 d1ni5a4 not modelled 98.7 97 Fold:MesJ substrate recognition domain-like Superfamily:MesJ substrate recognition domain-like Family:MesJ substrate recognition domain-like 47 d1wxia1 not modelled 98.6 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 48 c3n05B_ not modelled 98.6 17 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis 49 d1wy5a2 not modelled 98.6 11 Fold:MesJ substrate recognition domain-like Superfamily:MesJ substrate recognition domain-like Family:MesJ substrate recognition domain-like 50 d1ru8a_ not modelled 98.5 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 51 d1q15a1 not modelled 97.8 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 52 d2d13a1 not modelled 97.7 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 53 d1ct9a1 not modelled 97.7 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 54 c1ct9D_ not modelled 97.6 15 PDB header:ligase Chain: D: PDB Molecule:asparagine synthetase b; PDBTitle: crystal structure of asparagine synthetase b from2 escherichia coli 55 c3dlaD_ not modelled 97.6 17 PDB header:ligase Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don 56 d1jgta1 not modelled 97.5 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 57 c3ilvA_ not modelled 97.4 15 PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii 58 c1q15A_ not modelled 97.2 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:cara; PDBTitle: carbapenam synthetase 59 c1m1zB_ not modelled 97.2 11 PDB header:hydrolase Chain: B: PDB Molecule:beta-lactam synthetase; PDBTitle: beta-lactam synthetase apo enzyme 60 c3o1lB_ not modelled 94.6 12 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution 61 c3n0vD_ not modelled 93.9 12 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution 62 c3louB_ not modelled 93.9 12 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of formyltetrahydrofolate deformylase (yp_105254.1)2 from burkholderia mallei atcc 23344 at 1.90 a resolution 63 c2pfsA_ not modelled 93.8 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: crystal structure of universal stress protein from nitrosomonas2 europaea 64 d1tq8a_ not modelled 92.4 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 65 c3nbmA_ not modelled 92.2 12 PDB header:transferase Chain: A: PDB Molecule:pts system, lactose-specific iibc components; PDBTitle: the lactose-specific iib component domain structure of the2 phosphoenolpyruvate:carbohydrate phosphotransferase system (pts) from3 streptococcus pneumoniae. 66 c2l2qA_ not modelled 90.8 15 PDB header:transferase Chain: A: PDB Molecule:pts system, cellobiose-specific iib component (cela); PDBTitle: solution structure of cellobiose-specific phosphotransferase iib2 component protein from borrelia burgdorferi 67 d1q77a_ not modelled 89.5 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 68 c3mt0A_ not modelled 88.1 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pa1789; PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1 69 c3pcoD_ not modelled 87.8 16 PDB header:ligase Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 70 d2z3va1 not modelled 87.7 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 71 c3e15D_ not modelled 87.0 5 PDB header:hydrolase Chain: D: PDB Molecule:glucose-6-phosphate 1-dehydrogenase; PDBTitle: 6-phosphogluconolactonase from plasmodium vivax 72 c3mcuF_ not modelled 86.2 22 PDB header:oxidoreductase Chain: F: PDB Molecule:dipicolinate synthase, b chain; PDBTitle: crystal structure of the dipicolinate synthase chain b from2 bacillus cereus. northeast structural genomics consortium3 target bcr215. 73 c3loqA_ not modelled 86.1 11 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: the crystal structure of a universal stress protein from2 archaeoglobus fulgidus dsm 4304 74 d1fsfa_ not modelled 84.2 14 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:NagB-like 75 c3zquA_ not modelled 84.0 17 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: structure of a probable aromatic acid decarboxylase 76 c3lqkA_ not modelled 83.6 11 PDB header:oxidoreductase Chain: A: PDB Molecule:dipicolinate synthase subunit b; PDBTitle: crystal structure of dipicolinate synthase subunit b from bacillus2 halodurans c 77 c3hgmD_ not modelled 83.4 16 PDB header:signaling protein Chain: D: PDB Molecule:universal stress protein tead; PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata 78 d1meoa_ not modelled 83.3 17 Fold:Formyltransferase Superfamily:Formyltransferase Family:Formyltransferase 79 c3oc6A_ not modelled 82.5 15 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of 6-phosphogluconolactonase from mycobacterium2 smegmatis, apo form 80 d1p3y1_ not modelled 81.6 16 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 81 c2rhsB_ not modelled 80.7 24 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 82 d1iiba_ not modelled 80.4 15 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 83 c2ejbA_ not modelled 77.9 9 PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus 84 c3nrbD_ not modelled 77.7 14 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (puru,2 pp_1943) from pseudomonas putida kt2440 at 2.05 a resolution 85 c3p9xB_ not modelled 77.4 7 PDB header:transferase Chain: B: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of phosphoribosylglycinamide formyltransferase from2 bacillus halodurans 86 d1jjcb6 not modelled 77.3 18 Fold:PheT/TilS domain Superfamily:PheT/TilS domain Family:B3/B4 domain of PheRS, PheT 87 d1jmva_ not modelled 75.4 24 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 88 d1ne7a_ not modelled 74.3 9 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:NagB-like 89 c1j8yF_ not modelled 74.3 21 PDB header:signaling protein Chain: F: PDB Molecule:signal recognition 54 kda protein; PDBTitle: signal recognition particle conserved gtpase domain from a.2 ambivalens t112a mutant 90 c3hn6D_ not modelled 73.0 6 PDB header:isomerase Chain: D: PDB Molecule:glucosamine-6-phosphate deaminase; PDBTitle: crystal structure of glucosamine-6-phosphate deaminase from borrelia2 burgdorferi 91 c2ywrA_ not modelled 71.5 18 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of gar transformylase from aquifex2 aeolicus 92 c2dumD_ not modelled 71.2 11 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:hypothetical protein ph0823; PDBTitle: crystal structure of hypothetical protein, ph0823 93 c3icoA_ not modelled 71.1 14 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of 6-phosphogluconolactonase from2 mycobacterium tuberculosis 94 c2j7pA_ not modelled 70.6 18 PDB header:signal recognition Chain: A: PDB Molecule:signal recognition particle protein; PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy 95 c3qjgD_ not modelled 69.9 15 PDB header:oxidoreductase Chain: D: PDB Molecule:epidermin biosynthesis protein epid; PDBTitle: epidermin biosynthesis protein epid from staphylococcus aureus 96 d1pjqa3 not modelled 69.0 35 Fold:Siroheme synthase middle domains-like Superfamily:Siroheme synthase middle domains-like Family:Siroheme synthase middle domains-like 97 c3cssA_ not modelled 69.0 19 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of 6-phosphogluconolactonase from leishmania2 guyanensis 98 c3nyiA_ not modelled 68.6 16 PDB header:lipid binding protein Chain: A: PDB Molecule:fat acid-binding protein; PDBTitle: the crystal structure of a fat acid (stearic acid)-binding protein2 from eubacterium ventriosum atcc 27560. 99 d2gm3a1 not modelled 68.2 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 100 d1j8yf2 not modelled 67.8 21 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 101 c3dcjA_ not modelled 67.4 20 PDB header:transferase Chain: A: PDB Molecule:probable 5'-phosphoribosylglycinamide PDBTitle: crystal structure of glycinamide formyltransferase (purn)2 from mycobacterium tuberculosis in complex with 5-methyl-5,3 6,7,8-tetrahydrofolic acid derivative 102 d1ur4a_ not modelled 66.7 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 103 c3tqrA_ not modelled 66.5 23 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: structure of the phosphoribosylglycinamide formyltransferase (purn) in2 complex with ches from coxiella burnetii 104 d1mvla_ not modelled 66.2 21 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 105 c1mvlA_ not modelled 66.2 21 PDB header:lyase Chain: A: PDB Molecule:ppc decarboxylase athal3a; PDBTitle: ppc decarboxylase mutant c175s 106 d1qzua_ not modelled 66.1 15 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 107 c3dmdA_ not modelled 65.0 12 PDB header:transport protein Chain: A: PDB Molecule:signal recognition particle receptor; PDBTitle: structures and conformations in solution of the signal recognition2 particle receptor from the archaeon pyrococcus furiosus 108 c3lwdA_ not modelled 64.4 16 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of putative 6-phosphogluconolactonase (yp_574786.1)2 from chromohalobacter salexigens dsm 3043 at 1.88 a resolution 109 c1tvmA_ not modelled 64.0 14 PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system 110 c2px0D_ not modelled 64.0 21 PDB header:biosynthetic protein Chain: D: PDB Molecule:flagellar biosynthesis protein flhf; PDBTitle: crystal structure of flhf complexed with gmppnp/mg(2+) 111 d1vl1a_ not modelled 63.7 12 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:NagB-like 112 c3olqA_ not modelled 63.3 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:universal stress protein e; PDBTitle: the crystal structure of a universal stress protein e from proteus2 mirabilis hi4320 113 c3idfA_ not modelled 62.4 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:usp-like protein; PDBTitle: the crystal structure of a usp-like protein from wolinella2 succinogenes to 2.0a 114 d1sbza_ not modelled 61.8 18 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 115 c3s3tD_ not modelled 61.3 16 PDB header:chaperone Chain: D: PDB Molecule:nucleotide-binding protein, universal stress protein uspa PDBTitle: universal stress protein uspa from lactobacillus plantarum 116 d1rz3a_ not modelled 57.7 24 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 117 d1g5qa_ not modelled 56.2 12 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 118 d1l5ja3 not modelled 55.1 6 Fold:Aconitase iron-sulfur domain Superfamily:Aconitase iron-sulfur domain Family:Aconitase iron-sulfur domain 119 c3kcqA_ not modelled 53.4 17 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase; PDBTitle: crystal structure of phosphoribosylglycinamide formyltransferase from2 anaplasma phagocytophilum 120 c1vmaA_ not modelled 53.4 11 PDB header:protein transport Chain: A: PDB Molecule:cell division protein ftsy; PDBTitle: crystal structure of cell division protein ftsy (tm0570) from2 thermotoga maritima at 1.60 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0