Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP15891
DateMon Jul 2 19:13:22 BST 2012
Unique Job IDa839774b4009a372

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1hqz1_
Top template information
Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
Confidence and coverage
Confidence:100.0% Coverage: 23%
139 residues ( 23% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
339 residues ( 57%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
Warning: 69% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MALEPIDYTTHSREIDAEYLKIVRGSDPDTTWLIISPNAKKEYEPESTGSSFHDFLQLFD
Secondary structure 




























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Disorder  ???????????

































???

?








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   .........70.........80.........90.........100.........110.........120
Sequence  ETKVQYGLARVSPPGSDVEKIIIIGWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTA
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   .........130.........140.........150.........160.........170.........180
Sequence  RDEDDLDENELLMKISNAAGARYSIQTSSKQQGKASTPPVKKSFTPSKSPAPVSKKEPVK
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???
?????????????????????????????????????
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   .........190.........200.........210.........220.........230.........240
Sequence  TPSPAPAAKISSRVNDNNDDDDWNEPELKERDFDQAPLKPNQSSYKPIGKIDLQKVIAEE
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Disorder  ????????????????????????????????????????????????????????????
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   .........250.........260.........270.........280.........290.........300
Sequence  KAKEDPRLVQKPTAAGSKIDPSSDIANLKNESKLKRDSEFNSFLGTTKPPSMTESSLKND
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Disorder  ????????????????????????????????????????????????????????????
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   .........310.........320.........330.........340.........350.........360
Sequence  DDKVIKGFRNEKSPAQLWAERKAKQNSGNAETKAEAPKPEVPEDEPEGEPDVKDLKSKFE
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Disorder  ????????????????????????????????????????????????????????????
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   .........370.........380.........390.........400.........410.........420
Sequence  GLAASEKEEEEMENKFAPPPKKSEPTIISPKPFSKPQEPVKAEEAEQPKTDYKKIGNPLP
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   .........430.........440.........450.........460.........470.........480
Sequence  GMHIEADNEEEPEENDDDWDDDEDEAAQPPLPSRNVASGAPVQKEEPEQEEIAPSLPSRN
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   .........490.........500.........510.........520.........530.........540
Sequence  SIPAPKQEEAPEQAPEEEIEEEAEEAAPQLPSRSSAAPPPPPRRATPEKKPKENPWATAE
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   .........550.........560.........570.........580.........590..
Sequence  YDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN
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?









































??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1hqz chain 1

3D model

Region: 3 - 141
Aligned: 139
Modelled: 139
Confidence: 100.0%
Identity: 100%
Fold: Gelsolin-like
Superfamily: Actin depolymerizing proteins
Family: Cofilin-like

Phyre2

PDB 1udm chain A

3D model

Region: 4 - 147
Aligned: 141
Modelled: 144
Confidence: 100.0%
Identity: 16%
Fold: Gelsolin-like
Superfamily: Actin depolymerizing proteins
Family: Cofilin-like

Phyre2

PDB 1wnj chain A

3D model

Region: 5 - 148
Aligned: 141
Modelled: 144
Confidence: 100.0%
Identity: 17%
Fold: Gelsolin-like
Superfamily: Actin depolymerizing proteins
Family: Cofilin-like

Phyre2

PDB 1x67 chain A

3D model

Region: 5 - 141
Aligned: 135
Modelled: 137
Confidence: 100.0%
Identity: 20%
PDB header:protein binding
Chain: A: PDB Molecule:drebrin-like protein;
PDBTitle: solution structure of the cofilin homology domain of hip-552 (drebrin-like protein)

Phyre2

PDB 1t3y chain A domain 1

3D model

Region: 8 - 137
Aligned: 127
Modelled: 130
Confidence: 99.9%
Identity: 14%
Fold: Gelsolin-like
Superfamily: Actin depolymerizing proteins
Family: Cofilin-like

Phyre2

PDB 1mv3 chain A

3D model

Region: 393 - 591
Aligned: 199
Modelled: 199
Confidence: 99.9%
Identity: 15%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 1cfy chain A

3D model

Region: 12 - 137
Aligned: 123
Modelled: 126
Confidence: 99.8%
Identity: 21%
Fold: Gelsolin-like
Superfamily: Actin depolymerizing proteins
Family: Cofilin-like

Phyre2

PDB 1gri chain A

3D model

Region: 514 - 592
Aligned: 77
Modelled: 77
Confidence: 99.8%
Identity: 32%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 1cnu chain A

3D model

Region: 12 - 137
Aligned: 123
Modelled: 126
Confidence: 99.8%
Identity: 24%
Fold: Gelsolin-like
Superfamily: Actin depolymerizing proteins
Family: Cofilin-like

Phyre2

PDB 2kd5 chain A

3D model

Region: 1 - 135
Aligned: 127
Modelled: 129
Confidence: 99.8%
Identity: 24%
PDB header:hormone
Chain: A: PDB Molecule:actin severing and dynamics regulatory protein;
PDBTitle: solution structure of adf/cofilin (ldcof) from leishmania donovani

Phyre2

PDB 2rqr chain A

3D model

Region: 480 - 590
Aligned: 111
Modelled: 111
Confidence: 99.8%
Identity: 14%
PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex

Phyre2

PDB 2kym chain A

3D model

Region: 533 - 592
Aligned: 60
Modelled: 60
Confidence: 99.7%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide

Phyre2

PDB 2lqn chain A

3D model

Region: 476 - 591
Aligned: 114
Modelled: 114
Confidence: 99.7%
Identity: 17%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 1ng2 chain A domain 2

3D model

Region: 522 - 591
Aligned: 68
Modelled: 70
Confidence: 99.7%
Identity: 25%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2oi3 chain A

3D model

Region: 511 - 592
Aligned: 81
Modelled: 82
Confidence: 99.7%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)

Phyre2

PDB 2yup chain A

3D model

Region: 519 - 591
Aligned: 73
Modelled: 73
Confidence: 99.7%
Identity: 26%
PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin

Phyre2

PDB 3nmz chain D

3D model

Region: 531 - 591
Aligned: 59
Modelled: 59
Confidence: 99.7%
Identity: 29%
PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef

Phyre2

PDB 2dx1 chain A

3D model

Region: 532 - 591
Aligned: 58
Modelled: 60
Confidence: 99.7%
Identity: 29%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 2l3s chain A

3D model

Region: 484 - 592
Aligned: 107
Modelled: 107
Confidence: 99.7%
Identity: 14%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 1jo8 chain A

3D model

Region: 535 - 592
Aligned: 58
Modelled: 58
Confidence: 99.7%
Identity: 100%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2
1

d1hqz1_
2

d1udma_
3

d1wnja_
4

c1x67A_
5

d1t3ya1
6

c1mv3A_
7

d1cfya_
8

c1griA_
9

d1cnua_
10

c2kd5A_
11

c2rqrA_
12

c2kymA_
13

c2lqnA_
14

d1ng2a2
15

c2oi3A_
16

c2yupA_
17

c3nmzD_
18

c2dx1A_
19

c2l3sA_
20

d1jo8a_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1hqz1_



100.0 100 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
2d1udma_



100.0 16 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
3d1wnja_



100.0 17 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
4c1x67A_



100.0 20 PDB header:protein binding
Chain: A: PDB Molecule:drebrin-like protein;
PDBTitle: solution structure of the cofilin homology domain of hip-552 (drebrin-like protein)
5d1t3ya1



99.9 14 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
6c1mv3A_



99.9 15 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
7d1cfya_



99.8 21 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
8c1griA_



99.8 32 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
9d1cnua_



99.8 24 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
10c2kd5A_



99.8 24 PDB header:hormone
Chain: A: PDB Molecule:actin severing and dynamics regulatory protein;
PDBTitle: solution structure of adf/cofilin (ldcof) from leishmania donovani
11c2rqrA_



99.8 14 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
12c2kymA_



99.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
13c2lqnA_



99.7 17 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
14d1ng2a2



99.7 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
15c2oi3A_



99.7 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
16c2yupA_



99.7 26 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
17c3nmzD_



99.7 29 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
18c2dx1A_



99.7 29 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
19c2l3sA_



99.7 14 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
20d1jo8a_



99.7 100 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
21c2eyzA_



not modelled 99.7 16 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
22c2ebpA_



not modelled 99.7 22 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
23c2yt6A_



not modelled 99.7 24 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
24c2rqvA_



not modelled 99.7 24 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of sh3ci domain of bem1p
25c3rnjA_



not modelled 99.7 27 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)
26c2i2qA_



not modelled 99.7 22 PDB header:actin-binding protein
Chain: A: PDB Molecule:cofilin;
PDBTitle: fission yeast cofilin
27c2xfaA_



not modelled 99.7 18 PDB header:protein binding
Chain: A: PDB Molecule:actin depolymerization factor 2;
PDBTitle: crystal structure of plasmodium berghei actin2 depolymerization factor 2
28c2ysqA_



not modelled 99.7 31 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
29c2e5kA_



not modelled 99.7 22 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
30d1phta_



not modelled 99.7 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
31c2djqA_



not modelled 99.7 27 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
32c2ed1A_



not modelled 99.7 31 PDB header:signaling protein
Chain: A: PDB Molecule:130 kda phosphatidylinositol 4,5-biphosphate-
PDBTitle: solution structure of the sh3 domain of 130 kda2 phosphatidylinositol 4,5-biphosphate-dependent arf1 gtpase-3 activating protein
33d1f7sa_



not modelled 99.7 16 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
34c1x2qA_



not modelled 99.7 36 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
35c2cubA_



not modelled 99.7 32 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
36c2dbkA_



not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
37c3qwxX_



not modelled 99.7 17 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
38d1wiea_



not modelled 99.7 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
39c1x43A_



not modelled 99.7 28 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
40c2jxbA_



not modelled 99.7 21 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
41d1spka_



not modelled 99.7 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
42c2cudA_



not modelled 99.7 15 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
43c1x6gA_



not modelled 99.7 14 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
44c3qwyA_



not modelled 99.7 21 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
45c2d1xD_



not modelled 99.7 52 PDB header:cell invasion
Chain: D: PDB Molecule:cortactin isoform a;
PDBTitle: the crystal structure of the cortactin-sh3 domain and amap1-2 peptide complex
46c1x6bA_



not modelled 99.7 21 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
47c2kt1A_



not modelled 99.7 23 PDB header:protein binding
Chain: A: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: solution nmr structure of the sh3 domain from the p85beta2 subunit of phosphatidylinositol 3-kinase from h.sapiens,3 northeast structural genomics consortium target hr5531e
48c2ke9A_



not modelled 99.7 25 PDB header:protein binding
Chain: A: PDB Molecule:caskin-2;
PDBTitle: nmr solution structure of the caskin sh3 domain
49c2ct3A_



not modelled 99.7 27 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
50d1v6fa_



not modelled 99.7 12 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
51c2fpeB_



not modelled 99.7 18 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
52c1zukA_



not modelled 99.7 26 PDB header:contractile protein
Chain: A: PDB Molecule:myosin tail region-interacting protein mti1;
PDBTitle: yeast bbc1 sh3 domain complexed with a peptide from las17
53c2enmA_



not modelled 99.7 29 PDB header:endocytosis
Chain: A: PDB Molecule:sorting nexin-9;
PDBTitle: solution structure of the sh3 domain from mouse sorting2 nexin-9
54c2ed0A_



not modelled 99.7 32 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
55c2bzxA_



not modelled 99.7 28 PDB header:sh3 domain
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: atomic model of crkl-sh3c monomer
56c1yn8E_



not modelled 99.7 31 PDB header:unknown function
Chain: E: PDB Molecule:nap1-binding protein 2;
PDBTitle: sh3 domain of yeast nbp2
57c2eyxA_



not modelled 99.7 22 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
58c2nwmA_



not modelled 99.7 35 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
59c2dl3A_



not modelled 99.7 27 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
60d1udla_



not modelled 99.7 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
61c2dl8A_



not modelled 99.7 30 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
62c2yunA_



not modelled 99.7 32 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
63c2yuoA_



not modelled 99.7 34 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
64c2dbmA_



not modelled 99.7 34 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:sh3-containing grb2-like protein 2;
PDBTitle: solution structures of the sh3 domain of human sh3-2 containing grb2-like protein 2
65d1ov3a2



not modelled 99.7 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
66c2j06B_



not modelled 99.7 21 PDB header:signal transduction
Chain: B: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: crystal structure of the rasgap sh3 domain at 1.8 angstrom2 resolution
67c2ct4A_



not modelled 99.7 18 PDB header:signaling protein
Chain: A: PDB Molecule:cdc42-interacting protein 4;
PDBTitle: solution strutcure of the sh3 domain of the cdc42-2 interacting protein 4
68c2xmfA_



not modelled 99.7 44 PDB header:motor protein
Chain: A: PDB Molecule:myosin 1e sh3;
PDBTitle: myosin 1e sh3
69c2i0nA_



not modelled 99.7 26 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
70c2ekhA_



not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
71c2eyyA_



not modelled 99.6 18 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
72d1ue9a_



not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
73c2eczA_



not modelled 99.6 22 PDB header:signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain of sorbin and sh32 domain-containing protein 1
74c2epdA_



not modelled 99.6 31 PDB header:protein binding
Chain: A: PDB Molecule:rho gtpase-activating protein 4;
PDBTitle: solution structure of sh3 domain in rho-gtpase-activating2 protein 4
75c2eqiA_



not modelled 99.6 32 PDB header:immune system, hydrolase
Chain: A: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
76c2lcsA_



not modelled 99.6 32 PDB header:transferase, signaling protein
Chain: A: PDB Molecule:nap1-binding protein 2;
PDBTitle: yeast nbp2p sh3 domain in complex with a peptide from ste20p
77c1w70A_



not modelled 99.6 28 PDB header:sh3 domain
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: sh3 domain of p40phox complexed with c-terminal polyproline2 region of p47phox
78c2bz8B_



not modelled 99.6 41 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
79d2v1ra1



not modelled 99.6 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
80d1uffa_



not modelled 99.6 24 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
81c4esrB_



not modelled 99.6 36 PDB header:protein binding
Chain: B: PDB Molecule:jouberin;
PDBTitle: molecular and structural characterization of the sh3 domain of ahi-12 in regulation of cellular resistance of bcr-abl+ chronic myeloid3 leukemia cells to tyrosine kinase inhibitors
82c2d8hA_



not modelled 99.6 23 PDB header:unknown function
Chain: A: PDB Molecule:sh3yl1 protein;
PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
83d1uuea_



not modelled 99.6 29 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
84d1q8ga_



not modelled 99.6 21 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
85c1wi7A_



not modelled 99.6 27 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: solution structure of the sh3 domain of sh3-domain kinase2 binding protein 1
86c2df6A_



not modelled 99.6 29 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
87c2csqA_



not modelled 99.6 26 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
88c2l0aA_



not modelled 99.6 44 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 1;
PDBTitle: solution nmr structure of signal transducing adapter molecule 1 stam-12 from homo sapiens, northeast structural genomics consortium target3 hr4479e
89c2dl4A_



not modelled 99.6 26 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
90c1x69A_



not modelled 99.6 44 PDB header:signaling protein
Chain: A: PDB Molecule:cortactin isoform a;
PDBTitle: solution structures of the sh3 domain of human src2 substrate cortactin
91d1oota_



not modelled 99.6 39 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
92c2dmoA_



not modelled 99.6 18 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
93d1bb9a_



not modelled 99.6 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
94c1bb9A_



not modelled 99.6 28 PDB header:transferase
Chain: A: PDB Molecule:amphiphysin 2;
PDBTitle: crystal structure of the sh3 domain from rat amphiphysin 2
95c2drmB_



not modelled 99.6 43 PDB header:contractile protein
Chain: B: PDB Molecule:acanthamoeba myosin ib;
PDBTitle: acanthamoeba myosin i sh3 domain bound to acan125
96d1utia_



not modelled 99.6 39 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
97d1pwta_



not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
98c2l72A_



not modelled 99.6 21 PDB header:protein binding
Chain: A: PDB Molecule:actin depolymerizing factor, putative;
PDBTitle: solution structure and dynamics of adf from toxoplasma gondii (tgadf)
99d1gria2



not modelled 99.6 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
100d1k4us_



not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
101c2egeA_



not modelled 99.6 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein kiaa1666;
PDBTitle: solution structure of the third sh3 domain from human2 kiaa1666 protein
102c2dlpA_



not modelled 99.6 20 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
103d1jqqa_



not modelled 99.6 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
104c2dl5A_



not modelled 99.6 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:kiaa0769 protein;
PDBTitle: solution structure of the first sh3 domain of human2 kiaa0769 protein
105d1gcqa_



not modelled 99.6 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
106c1wyxA_



not modelled 99.6 36 PDB header:cell adhesion
Chain: A: PDB Molecule:crk-associated substrate;
PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
107d1ujya_



not modelled 99.6 27 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
108d1uj0a_



not modelled 99.6 44 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
109d1wfsa_



not modelled 99.6 14 Fold:Gelsolin-like
Superfamily:Actin depolymerizing proteins
Family:Cofilin-like
110c1z9zA_



not modelled 99.6 29 PDB header:structural protein
Chain: A: PDB Molecule:cytoskeleton assembly control protein sla1;
PDBTitle: crystal structure of yeast sla1 sh3 domain 3
111d1arka_



not modelled 99.6 35 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
112d1sema_



not modelled 99.6 40 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
113c2azsA_



not modelled 99.6 37 PDB header:signaling protein
Chain: A: PDB Molecule:sh2-sh3 adapter protein drk;
PDBTitle: nmr structure of the n-terminal sh3 domain of drk2 (calculated without noe restraints)
114c2o2oA_



not modelled 99.6 27 PDB header:protein binding
Chain: A: PDB Molecule:sh3-domain kinase-binding protein 1;
PDBTitle: solution structure of domain b from human cin85 protein
115d1uhfa_



not modelled 99.6 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
116d1i1ja_



not modelled 99.6 21 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
117d1j3ta_



not modelled 99.6 36 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
118d1wlpb2



not modelled 99.6 19 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
119c2js0A_



not modelled 99.6 37 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of second sh3 domain of adaptor nck
120c1wx6A_



not modelled 99.6 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cytoplasmic protein nck2;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2

Binding site prediction 

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