Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	L	K	E	K	T	Q	S	L	F	A	N	A	F	G	Y	P	A	T	H	T	I	Q	A	P	G	R	V	N	L	I	G	E	H	T	D	Y	N	D	G	F	V	L	P	C	A	I	D	Y	Q	T	V	I	S	C	A	P	R	D
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	R	K	V	R	V	M	A	A	D	Y	E	N	Q	L	D	E	F	S	L	D	A	P	I	V	A	H	E	N	Y	Q	W	A	N	Y	V	R	G	V	V	K	H	L	Q	L	R	N	N	S	F	G	G	V	D	M	V	I	S	G	N
Secondary structure
SS confidence
Disorder																										?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	P	Q	G	A	G	L	S	S	S	A	S	L	E	V	A	V	G	T	V	L	Q	Q	L	Y	H	L	P	L	D	G	A	Q	I	A	L	N	G	Q	E	A	E	N	Q	F	V	G	C	N	C	G	I	M	D	Q	L	I	S	A	L
Secondary structure
SS confidence
Disorder				?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	K	K	D	H	A	L	L	I	D	C	R	S	L	G	T	K	A	V	S	M	P	K	G	V	A	V	V	I	I	N	S	N	F	K	R	T	L	V	G	S	E	Y	N	T	R	R	E	Q	C	E	T	G	A	R	F	F	Q	Q	P
Secondary structure
SS confidence
Disorder																																								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	L	R	D	V	T	I	E	E	F	N	A	V	A	H	E	L	D	P	I	V	A	K	R	V	R	H	I	L	T	E	N	A	R	T	V	E	A	A	S	A	L	E	Q	G	D	L	K	R	M	G	E	L	M	A	E	S	H	A	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		M	R	D	D	F	E	I	T	V	P	Q	I	D	T	L	V	E	I	V	K	A	V	I	G	D	K	G	G	V	R	M	T	G	G	G	F	G	G	C	I	V	A	L	I	P	E	E	L	V	P	A	V	Q	Q	A	V	A	E	Q	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Sequence		E	A	K	T	G	I	K	E	T	F	Y	V	C	K	P	S	Q	G	A	G	Q	C
Secondary structure
SS confidence
Disorder																		?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1pie chain A Region: 2 - 380 Aligned: 378 Modelled: 379 Confidence: 100.0% Identity: 35% PDB header:transferase Chain: A: PDB Molecule:galactokinase; PDBTitle: crystal structure of lactococcus lactis galactokinase2 complexed with galactose Phyre2 PDB 2aj4 chain B Region: 2 - 380 Aligned: 376 Modelled: 379 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: B: PDB Molecule:galactokinase; PDBTitle: crystal structure of saccharomyces cerevisiae galactokinase2 in complex with galactose and mg:amppnp Phyre2 PDB 1wuu chain A Region: 2 - 380 Aligned: 370 Modelled: 373 Confidence: 100.0% Identity: 43% PDB header:transferase Chain: A: PDB Molecule:galactokinase; PDBTitle: crystal structure of human galactokinase complexed with2 mgamppnp and galactose Phyre2 PDB 2a2c chain A Region: 4 - 380 Aligned: 368 Modelled: 373 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: A: PDB Molecule:n-acetylgalactosamine kinase; PDBTitle: x-ray structure of human n-acetyl galactosamine kinase2 complexed with mg-adp and n-acetyl galactosamine 1-3 phosphate Phyre2 PDB 2cz9 chain A Region: 21 - 380 Aligned: 344 Modelled: 360 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:probable galactokinase; PDBTitle: crystal structure of galactokinase from pyrococcus horikoshi Phyre2 PDB 2r42 chain A Region: 18 - 379 Aligned: 327 Modelled: 332 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: the biochemical and structural basis for feedback2 inhibition of mevalonate kinase and isoprenoid metabolism Phyre2 PDB 3k17 chain A Region: 21 - 378 Aligned: 323 Modelled: 328 Confidence: 100.0% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:lin0012 protein; PDBTitle: crystal structure of a lin0012 protein from listeria innocua Phyre2 PDB 2hfu chain B Region: 24 - 376 Aligned: 310 Modelled: 325 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:mevalonate kinase, putative; PDBTitle: crystal structure of l. major mevalonate kinase in complex2 with r-mevalonate Phyre2 PDB 1k47 chain F Region: 18 - 372 Aligned: 295 Modelled: 309 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: F: PDB Molecule:phosphomevalonate kinase; PDBTitle: crystal structure of the streptococcus pneumoniae2 phosphomevalonate kinase (pmk) Phyre2 PDB 1kkh chain A Region: 17 - 367 Aligned: 307 Modelled: 320 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: crystal structure of the methanococcus jannaschii2 mevalonate kinase Phyre2 PDB 2x7i chain A Region: 21 - 368 Aligned: 288 Modelled: 296 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: crystal structure of mevalonate kinase from methicillin-2 resistant staphylococcus aureus mrsa252 Phyre2 PDB 2oi2 chain A Region: 21 - 368 Aligned: 280 Modelled: 284 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: streptococcus pneumoniae mevalonate kinase in complex with2 diphosphomevalonate Phyre2 PDB 1pie chain A domain 1 Region: 2 - 203 Aligned: 202 Modelled: 202 Confidence: 100.0% Identity: 33% Fold: Ribosomal protein S5 domain 2-like Superfamily: Ribosomal protein S5 domain 2-like Family: GHMP Kinase, N-terminal domain Phyre2 PDB 3k85 chain B Region: 21 - 358 Aligned: 277 Modelled: 294 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:d-glycero-d-manno-heptose 1-phosphate kinase; PDBTitle: crystal structure of a d-glycero-d-manno-heptose 1-phosphate2 kinase from bacteriodes thetaiotaomicron Phyre2 PDB 1wuu chain A domain 1 Region: 2 - 204 Aligned: 201 Modelled: 197 Confidence: 100.0% Identity: 43% Fold: Ribosomal protein S5 domain 2-like Superfamily: Ribosomal protein S5 domain 2-like Family: GHMP Kinase, N-terminal domain Phyre2 PDB 1fwl chain D Region: 21 - 379 Aligned: 290 Modelled: 311 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:homoserine kinase; PDBTitle: crystal structure of homoserine kinase Phyre2 PDB 1pie chain A domain 2 Region: 204 - 381 Aligned: 177 Modelled: 178 Confidence: 100.0% Identity: 37% Fold: Ferredoxin-like Superfamily: GHMP Kinase, C-terminal domain Family: Galactokinase Phyre2 PDB 1s4e chain A domain 2 Region: 204 - 380 Aligned: 171 Modelled: 177 Confidence: 100.0% Identity: 30% Fold: Ferredoxin-like Superfamily: GHMP Kinase, C-terminal domain Family: Galactokinase Phyre2 PDB 2gs8 chain A Region: 21 - 381 Aligned: 289 Modelled: 314 Confidence: 100.0% Identity: 17% PDB header:lyase Chain: A: PDB Molecule:mevalonate pyrophosphate decarboxylase; PDBTitle: structure of mevalonate pyrophosphate decarboxylase from streptococcus2 pyogenes Phyre2 PDB 3hul chain A Region: 20 - 379 Aligned: 270 Modelled: 292 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:homoserine kinase; PDBTitle: structure of putative homoserine kinase thrb from listeria2 monocytogenes Phyre2 1 c1pieA_ 2 c2aj4B_ 3 c1wuuA_ 4 c2a2cA_ 5 c2cz9A_ 6 c2r42A_ 7 c3k17A_ 8 c2hfuB_ 9 c1k47F_ 10 c1kkhA_ 11 c2x7iA_ 12 c2oi2A_ 13 d1piea1 14 c3k85B_ 15 d1wuua1 16 c1fwlD_ 17 d1piea2 18 d1s4ea2 19 c2gs8A_ 20 c3hulA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1pieA_ 100.0 35 PDB header:transferase Chain: A: PDB Molecule:galactokinase; PDBTitle: crystal structure of lactococcus lactis galactokinase2 complexed with galactose 2 c2aj4B_ 100.0 29 PDB header:transferase Chain: B: PDB Molecule:galactokinase; PDBTitle: crystal structure of saccharomyces cerevisiae galactokinase2 in complex with galactose and mg:amppnp 3 c1wuuA_ 100.0 43 PDB header:transferase Chain: A: PDB Molecule:galactokinase; PDBTitle: crystal structure of human galactokinase complexed with2 mgamppnp and galactose 4 c2a2cA_ 100.0 31 PDB header:transferase Chain: A: PDB Molecule:n-acetylgalactosamine kinase; PDBTitle: x-ray structure of human n-acetyl galactosamine kinase2 complexed with mg-adp and n-acetyl galactosamine 1-3 phosphate 5 c2cz9A_ 100.0 32 PDB header:transferase Chain: A: PDB Molecule:probable galactokinase; PDBTitle: crystal structure of galactokinase from pyrococcus horikoshi 6 c2r42A_ 100.0 20 PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: the biochemical and structural basis for feedback2 inhibition of mevalonate kinase and isoprenoid metabolism 7 c3k17A_ 100.0 12 PDB header:transferase Chain: A: PDB Molecule:lin0012 protein; PDBTitle: crystal structure of a lin0012 protein from listeria innocua 8 c2hfuB_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:mevalonate kinase, putative; PDBTitle: crystal structure of l. major mevalonate kinase in complex2 with r-mevalonate 9 c1k47F_ 100.0 17 PDB header:transferase Chain: F: PDB Molecule:phosphomevalonate kinase; PDBTitle: crystal structure of the streptococcus pneumoniae2 phosphomevalonate kinase (pmk) 10 c1kkhA_ 100.0 22 PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: crystal structure of the methanococcus jannaschii2 mevalonate kinase 11 c2x7iA_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: crystal structure of mevalonate kinase from methicillin-2 resistant staphylococcus aureus mrsa252 12 c2oi2A_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:mevalonate kinase; PDBTitle: streptococcus pneumoniae mevalonate kinase in complex with2 diphosphomevalonate 13 d1piea1 100.0 33 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 14 c3k85B_ 100.0 17 PDB header:transferase Chain: B: PDB Molecule:d-glycero-d-manno-heptose 1-phosphate kinase; PDBTitle: crystal structure of a d-glycero-d-manno-heptose 1-phosphate2 kinase from bacteriodes thetaiotaomicron 15 d1wuua1 100.0 43 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 16 c1fwlD_ 100.0 20 PDB header:transferase Chain: D: PDB Molecule:homoserine kinase; PDBTitle: crystal structure of homoserine kinase 17 d1piea2 100.0 37 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Galactokinase 18 d1s4ea2 100.0 30 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Galactokinase 19 c2gs8A_ 100.0 17 PDB header:lyase Chain: A: PDB Molecule:mevalonate pyrophosphate decarboxylase; PDBTitle: structure of mevalonate pyrophosphate decarboxylase from streptococcus2 pyogenes 20 c3hulA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:homoserine kinase; PDBTitle: structure of putative homoserine kinase thrb from listeria2 monocytogenes 21 d1wuua2 not modelled 100.0 42 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Galactokinase 22 d1s4ea1 not modelled 100.0 44 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 23 c2hk3A_ not modelled 100.0 16 PDB header:lyase Chain: A: PDB Molecule:diphosphomevalonate decarboxylase; PDBTitle: crystal structure of mevalonate diphosphate decarboxylase2 from staphylococcus aureus (orthorhombic form) 24 d1kkha1 not modelled 100.0 22 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 25 c2v34B_ not modelled 100.0 17 PDB header:transferase Chain: B: PDB Molecule:4-diphosphocytidyl-2c-methyl-d-erythritol kinase; PDBTitle: ispe in complex with cytidine and ligand 26 d1kvka1 not modelled 100.0 23 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 27 c1uekA_ not modelled 100.0 20 PDB header:transferase Chain: A: PDB Molecule:4-(cytidine 5'-diphospho)-2c-methyl-d-erythritol PDBTitle: crystal structure of 4-(cytidine 5'-diphospho)-2c-methyl-d-2 erythritol kinase 28 c1oj4B_ not modelled 100.0 21 PDB header:transferase Chain: B: PDB Molecule:4-diphosphocytidyl-2-c-methyl-d-erythritol PDBTitle: ternary complex of2 4-diphosphocytidyl-2-c-methyl-d-erythritol kinase 29 d1k47a1 not modelled 100.0 18 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 30 c3ltoB_ not modelled 99.9 16 PDB header:lyase Chain: B: PDB Molecule:mevalonate diphosphate decarboxylase; PDBTitle: crystal structure of a mevalonate diphosphate decarboxylase2 from legionella pneumophila 31 d1h72c1 not modelled 99.9 20 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 32 d1oj4a1 not modelled 99.8 23 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 33 d1k47a2 not modelled 99.8 17 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Phosphomevalonate kinase (PMK) 34 d1kvka2 not modelled 99.8 19 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Mevalonate kinase 35 c2hkeB_ not modelled 99.7 18 PDB header:lyase Chain: B: PDB Molecule:diphosphomevalonate decarboxylase, putative; PDBTitle: mevalonate diphosphate decarboxylase from trypanosoma brucei 36 d1kkha2 not modelled 99.7 24 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Mevalonate kinase 37 d1ueka1 not modelled 99.7 23 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 38 c1fi4A_ not modelled 99.6 18 PDB header:lyase Chain: A: PDB Molecule:mevalonate 5-diphosphate decarboxylase; PDBTitle: the x-ray crystal structure of mevalonate 5-diphosphate decarboxylase2 at 2.3 angstrom resolution. 39 d1fi4a1 not modelled 99.4 21 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:GHMP Kinase, N-terminal domain 40 c3f0nB_ not modelled 99.1 18 PDB header:lyase Chain: B: PDB Molecule:mevalonate pyrophosphate decarboxylase; PDBTitle: mus musculus mevalonate pyrophosphate decarboxylase 41 d1h72c2 not modelled 98.8 21 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Homoserine kinase 42 d1ueka2 not modelled 97.7 18 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE 43 d1oj4a2 not modelled 96.9 15 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:4-(cytidine 5'-diphospho)-2C-methyl-D-erythritol kinase IspE 44 d1fi4a2 not modelled 96.0 14 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Mevalonate 5-diphosphate decarboxylase 45 c3c7bA_ not modelled 79.6 13 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase, dissimilatory-type subunit alpha; PDBTitle: structure of the dissimilatory sulfite reductase from archaeoglobus2 fulgidus 46 c2v4jA_ not modelled 68.6 14 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase, dissimilatory-type subunit PDBTitle: the crystal structure of desulfovibrio vulgaris2 dissimilatory sulfite reductase bound to dsrc provides3 novel insights into the mechanism of sulfate respiration 47 d3c7bb2 not modelled 60.3 14 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:DsrA/DsrB N-terminal-domain-like 48 d1lb2b_ not modelled 39.2 11 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 49 d2v4jb2 not modelled 35.9 17 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:DsrA/DsrB N-terminal-domain-like 50 d1doqa_ not modelled 34.1 13 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 51 c2v4jE_ not modelled 31.3 17 PDB header:oxidoreductase Chain: E: PDB Molecule:sulfite reductase, dissimilatory-type subunit PDBTitle: the crystal structure of desulfovibrio vulgaris2 dissimilatory sulfite reductase bound to dsrc provides3 novel insights into the mechanism of sulfate respiration 52 d1z3eb1 not modelled 30.8 11 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 53 c3c7bE_ not modelled 30.3 14 PDB header:oxidoreductase Chain: E: PDB Molecule:sulfite reductase, dissimilatory-type subunit beta; PDBTitle: structure of the dissimilatory sulfite reductase from archaeoglobus2 fulgidus 54 d2cz4a1 not modelled 26.0 21 Fold:Ferredoxin-like Superfamily:GlnB-like Family:Prokaryotic signal transducing protein 55 d1zj8a1 not modelled 25.5 13 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:Duplicated SiR/NiR-like domains 1 and 3 56 d2pv7a1 not modelled 23.9 15 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:TyrA dimerization domain-like 57 d1cooa_ not modelled 23.6 14 Fold:SAM domain-like Superfamily:C-terminal domain of RNA polymerase alpha subunit Family:C-terminal domain of RNA polymerase alpha subunit 58 d2z15a1 not modelled 21.8 23 Fold:BTG domain-like Superfamily:BTG domain-like Family:BTG domain-like 59 c3mnfA_ not modelled 20.5 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:pac2 family protein; PDBTitle: crystal structure of pac2 family protein from streptomyces avermitilis2 ma 60 d3e9va1 not modelled 19.0 26 Fold:BTG domain-like Superfamily:BTG domain-like Family:BTG domain-like 61 d1ihwa_ not modelled 19.0 22 Fold:SH3-like barrel Superfamily:DNA-binding domain of retroviral integrase Family:DNA-binding domain of retroviral integrase 62 c3sftA_ not modelled 18.9 23 PDB header:hydrolase Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate PDBTitle: crystal structure of thermotoga maritima cheb methylesterase catalytic2 domain 63 d1ex4a1 not modelled 18.7 14 Fold:SH3-like barrel Superfamily:DNA-binding domain of retroviral integrase Family:DNA-binding domain of retroviral integrase 64 c3gaaB_ not modelled 17.2 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein ta1441; PDBTitle: the crystal structure of the protein with unknown function from2 thermoplasma acidophilum 65 c2dzrA_ not modelled 16.3 40 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-067, a gtf2i domain in human2 cdna 66 d1chda_ not modelled 15.9 32 Fold:Methylesterase CheB, C-terminal domain Superfamily:Methylesterase CheB, C-terminal domain Family:Methylesterase CheB, C-terminal domain 67 c2p90B_ not modelled 15.7 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein cgl1923; PDBTitle: the crystal structure of a protein of unknown function from2 corynebacterium glutamicum atcc 13032 68 d2bv3a3 not modelled 15.6 12 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:Translational machinery components 69 c2d99A_ not modelled 15.5 13 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-048, a gtf2i domain in human2 cdna 70 d3c7ba2 not modelled 14.0 11 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:DsrA/DsrB N-terminal-domain-like 71 c2y9jt_ not modelled 13.7 10 PDB header:protein transport Chain: T: PDB Molecule:protein prgh; PDBTitle: three-dimensional model of salmonella's needle complex at2 subnanometer resolution 72 c2e3lA_ not modelled 13.7 20 PDB header:transcription Chain: A: PDB Molecule:transcription factor gtf2ird2 beta; PDBTitle: solution structure of rsgi ruh-068, a gtf2i domain in human2 cdna 73 c1vkrA_ not modelled 13.6 29 PDB header:transferase Chain: A: PDB Molecule:mannitol-specific pts system enzyme iiabc components; PDBTitle: structure of iib domain of the mannitol-specific permease enzyme ii 74 d1vkra_ not modelled 13.6 29 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:PTS system IIB component-like Family:PTS system, Lactose/Cellobiose specific IIB subunit 75 c3m05A_ not modelled 13.4 20 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pepe_1480; PDBTitle: the crystal structure of a functionally unknown protein2 pepe_1480 from pediococcus pentosaceus atcc 25745 76 d1a6qa1 not modelled 12.4 30 Fold:Another 3-helical bundle Superfamily:Protein serine/threonine phosphatase 2C, C-terminal domain Family:Protein serine/threonine phosphatase 2C, C-terminal domain 77 d1mg7a2 not modelled 12.3 31 Fold:Ferredoxin-like Superfamily:GHMP Kinase, C-terminal domain Family:Early switch protein XOL-1 78 c2dn5A_ not modelled 12.2 36 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-057, a gtf2i domain in human2 cdna 79 c3u4gA_ not modelled 11.7 31 PDB header:transferase Chain: A: PDB Molecule:namn:dmb phosphoribosyltransferase; PDBTitle: the structure of cobt from pyrococcus horikoshii 80 c3ff2A_ not modelled 11.6 8 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized cystatin fold protein (yp_497570.1) from PDBTitle: crystal structure of an uncharacterized cystatin fold protein2 (saro_2299) from novosphingobium aromaticivorans dsm at 1.90 a3 resolution 81 d1q60a_ not modelled 10.4 43 Fold:GTF2I-like repeat Superfamily:GTF2I-like repeat Family:GTF2I-like repeat 82 d1ri9a_ not modelled 10.3 26 Fold:SH3-like barrel Superfamily:SH3-domain Family:SH3-domain 83 c1ri9A_ not modelled 10.3 26 PDB header:signaling protein Chain: A: PDB Molecule:fyn-binding protein; PDBTitle: structure of a helically extended sh3 domain of the t cell2 adapter protein adap 84 d1szpb1 not modelled 10.1 11 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 85 d2axtj1 not modelled 10.1 83 Fold:Single transmembrane helix Superfamily:Photosystem II reaction center protein J, PsbJ Family:PsbJ-like 86 c3e0dA_ not modelled 10.1 25 PDB header:transferase/dna Chain: A: PDB Molecule:dna polymerase iii subunit alpha; PDBTitle: insights into the replisome from the crystral structure of2 the ternary complex of the eubacterial dna polymerase iii3 alpha-subunit 87 d1c6vx_ not modelled 9.8 18 Fold:SH3-like barrel Superfamily:DNA-binding domain of retroviral integrase Family:DNA-binding domain of retroviral integrase 88 c1c6vX_ not modelled 9.8 18 PDB header:dna binding protein Chain: X: PDB Molecule:protein (siu89134); PDBTitle: siv integrase (catalytic domain + dna biding domain2 comprising residues 50-293) mutant with phe 185 replaced3 by his (f185h) 89 d2hmfa2 not modelled 9.8 20 Fold:Ferredoxin-like Superfamily:ACT-like Family:Aspartokinase allosteric domain-like 90 c2dn4A_ not modelled 9.8 21 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i; PDBTitle: solution structure of rsgi ruh-060, a gtf2i domain in human2 cdna 91 d2gexa1 not modelled 9.7 16 Fold:Cystatin-like Superfamily:NTF2-like Family:SnoaL-like polyketide cyclase 92 c2ed2A_ not modelled 9.4 29 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i; PDBTitle: solution structure of rsgi ruh-069, a gtf2i domain in human2 cdna 93 c2dzqA_ not modelled 9.2 21 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i repeat domain- PDBTitle: solution structure of rsgi ruh-066, a gtf2i domain in human2 cdna 94 c2ejeA_ not modelled 9.2 43 PDB header:transcription Chain: A: PDB Molecule:general transcription factor ii-i; PDBTitle: solution structure of rsgi ruh-071, a gtf2i domain in human2 cdna 95 c2akjA_ not modelled 9.1 10 PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin--nitrite reductase, chloroplast; PDBTitle: structure of spinach nitrite reductase 96 d1vola2 not modelled 9.1 16 Fold:Cyclin-like Superfamily:Cyclin-like Family:Transcription factor IIB (TFIIB), core domain 97 d2i1qa1 not modelled 9.0 9 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 98 c5aopA_ not modelled 8.6 14 PDB header:oxidoreductase Chain: A: PDB Molecule:sulfite reductase hemoprotein; PDBTitle: sulfite reductase structure reduced with crii edta, 5-coordinate2 siroheme, siroheme feii, [4fe-4s] +1 99 d3ec9a1 not modelled 8.5 12 Fold:Cystatin-like Superfamily:NTF2-like Family:PhzA/PhzB-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0