Phyre 2 Results for P16919

Email	l.a.kelley@imperial.ac.uk
Description	P16919
Date	Wed Jan 25 15:20:40 GMT 2012
Unique Job ID	f54722af1d87bd4f

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2oy7A_

Top template information

PDB header:membrane protein
Chain: A: PDB Molecule:outer surface protein a;
PDBTitle: the crystal structure of ospa mutant

Confidence and coverage

Confidence:

96.5%

Coverage:

19%

269 residues ( 19% of your sequence) have been modelled with 96.5% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M S G K P A A R Q G D M T Q Y G G P I V Q G S A G V R I G A P T G V A C S V C P G G M T S G N P V N P L L G A K V L P G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?
? ? ? ? ?
? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence E T D L A L P G P L P F I L S R T Y S S Y R T K T P A P V G V F G P G W K A P S D I R L Q L R D D G L I L N D N G G R S

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence I H F E P L L P G E A V Y S R S E S M W L V R G G K A A Q P D G H T L A R L W G A L P P D I R L S P H L Y L A T N S A Q

Secondary structure

SS confidence

Disorder
?
? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence G P W W I L G W S E R V P G A E D V L P A P L P P Y R V L T G M A D R F G R T L T Y R R E A A G D L A G E I T G V T D G

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence A G R E F R L V L T T Q A Q R A E E A R T S S L S S S D S S R P L S A S A F P D T L P G T E Y G P D R G I R L S A V W L

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence M H D P A Y P E S L P A A P L V R Y T Y T E A G E L L A V Y D R S N T Q V R A F T Y D A Q H P G R M V A H R Y A G R P E

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence M R Y R Y D D T G R V V E Q L N P A G L S Y R Y L Y E Q D R I T V T D S L N R R E V L H T E G G A G L K R V V K K E L A

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence D G S V T R S G Y D A A G R L T A Q T D A A G R R T E Y G L N V V S G D I T D I T T P D G R E T K F Y Y N D G N Q L T A

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence V V S P D G L E S R R E Y D E P G R L V S E T S R S G E T V R Y R Y D D A H S E L P A T T T D A T G S T R Q M T W S R Y

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence G Q L L A F T D C S G Y Q T R Y E Y D R F G Q M T A V H R E E G I S L Y R R Y D N R G R L T S V K D A Q G R E T R Y E Y

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence N A A G D L T A V I T P D G N R S E T Q Y D A W G K A V S T T Q G G L T R S M E Y D A A G R V I S L T N E N G S H S V F

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence S Y D A L D R L V Q Q G G F D G R T Q R Y H Y D L T G K L T Q S E D E G L V I L W Y Y D E S D R I T H R T V N G E P A E

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence Q W Q Y D G H G W L T D I S H L S E G H R V A V H Y G Y D D K G R L T G E C Q T V E N P E T G E L L W Q H E T K H A Y N

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence E Q G L A N R V T P D S L P P V E W L T Y G S G Y L A G M K L G G T P L V E Y T R D R L H R E T V R S F G S M A G S N A

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence A Y E L T S T Y T P A G Q L Q S Q H L N S L V Y D R D Y G W S D N G D L V R I S G P R Q T R E Y G Y S A T G R L E S V R

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence T L A P D L D I R I P Y A T D P A G N R L P D P E L H P D S T L T V W P D N R I A E D A H Y V Y R H D E Y G R L T E K T

Secondary structure

SS confidence

Disorder
?
?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence D R I P A G V I R T D D E R T H H Y H Y D S Q H R L V F Y T R I Q H G E P L V E S R Y L Y D P L G R R M A K R V W R R E

Secondary structure

SS confidence

Disorder
? ?
?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence R D L T G W M S L S R K P E V T W Y G W D G D R L T T V Q T D T T R I Q T V Y E P G S F T P L I R V E T E N G E R E K A

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence Q R R S L A E T L Q Q E G S E N G H G V V F P A E L V R L L D R L E E E I R A D R V S S E S R A W L A Q C G L T V E Q L

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence A R Q V E P E Y T P A R K A H L Y H C D H R G L P L A L I S E D G N T A W S A E Y D E W G N Q L N E E N P H H V Y Q P Y

Secondary structure

SS confidence

Disorder
? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence R L P G Q Q H D E E S G L Y Y N R H R Y Y D P L Q G R Y I T Q D P M G L K G G W N L Y Q Y P L N P L Q Q I D P M G L L Q

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320

Sequence T W D D A R S G A C T G G V C G V L S R I I G P S K F D S T A D A A L D A L K E T Q N R S L C N D M E Y S G I V C K D T

Secondary structure

SS confidence

Disorder
? ?
? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1330 . . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380

Sequence N G K Y F A S K A E T D N L R K E S Y P L K R K C P T G T D R V A A Y H T H G A D S H G D Y V D E F F S S S D K N L V R

Secondary structure

SS confidence

Disorder ? ? ? ? ? ?
? ? ? ?
? ? ?
? ?
?
?
?

Disorder confidence

. . . . . . . . . 1390 . . . . . . . . . 1400 . . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . .

Sequence S K D N N L E A F Y L A T P D G R F E A L N N K G E Y I F I R N S V P G L S S V C I P Y H D

Secondary structure

SS confidence

Disorder ?
? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2oy7 chain A

Region: 389 - 666
Aligned: 269
Modelled: 278
Confidence: 96.5%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:outer surface protein a;
PDBTitle: the crystal structure of ospa mutant

Phyre2

PDB 1ryp chain I

Region: 1250 - 1352
Aligned: 102
Modelled: 103
Confidence: 46.2%
Identity: 20%
Fold: Ntn hydrolase-like
Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family: Proteasome subunits

Phyre2

PDB 1x3z chain A domain 1

Region: 1220 - 1253
Aligned: 33
Modelled: 34
Confidence: 46.0%
Identity: 18%
Fold: Cysteine proteinases
Superfamily: Cysteine proteinases
Family: Transglutaminase core

Phyre2

PDB 1iru chain A

Region: 1250 - 1330
Aligned: 81
Modelled: 81
Confidence: 43.0%
Identity: 16%
Fold: Ntn hydrolase-like
Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family: Proteasome subunits

Phyre2

PDB 3nqh chain A

Region: 1118 - 1350
Aligned: 213
Modelled: 233
Confidence: 42.9%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:glycosyl hydrolase;
PDBTitle: crystal structure of a glycosyl hydrolase (bt_2959) from bacteroides2 thetaiotaomicron vpi-5482 at 2.11 a resolution

Phyre2

PDB 1j5q chain B

Region: 1200 - 1297
Aligned: 73
Modelled: 81
Confidence: 37.5%
Identity: 25%
PDB header:viral protein
Chain: B: PDB Molecule:major capsid protein;
PDBTitle: the structure and evolution of the major capsid protein of a large,2 lipid-containing, dna virus.

Phyre2

PDB 1n7d chain A

Region: 474 - 680
Aligned: 207
Modelled: 207
Confidence: 36.6%
Identity: 10%
PDB header:lipid transport
Chain: A: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: extracellular domain of the ldl receptor

Phyre2

PDB 1j2p chain A

Region: 1250 - 1330
Aligned: 81
Modelled: 81
Confidence: 33.2%
Identity: 19%
Fold: Ntn hydrolase-like
Superfamily: N-terminal nucleophile aminohydrolases (Ntn hydrolases)
Family: Proteasome subunits

Phyre2

PDB 1m4x chain C

Region: 1239 - 1297
Aligned: 41
Modelled: 42
Confidence: 30.7%
Identity: 29%
PDB header:virus
Chain: C: PDB Molecule:pbcv-1 virus capsid;
PDBTitle: pbcv-1 virus capsid, quasi-atomic model

Phyre2

PDB 3esw chain A

Region: 1220 - 1253
Aligned: 33
Modelled: 34
Confidence: 30.5%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:peptide-n(4)-(n-acetyl-beta-glucosaminyl)asparagine
PDBTitle: complex of yeast pngase with glcnac2-iac.

Phyre2

PDB 2ivz chain D

Region: 390 - 630
Aligned: 237
Modelled: 241
Confidence: 30.3%
Identity: 11%
PDB header:protein transport/hydrolase
Chain: D: PDB Molecule:protein tolb;
PDBTitle: structure of tolb in complex with a peptide of the colicin2 e9 t-domain

Phyre2

PDB 2f4m chain A domain 1

Region: 1220 - 1253
Aligned: 34
Modelled: 34
Confidence: 28.5%
Identity: 26%
Fold: Cysteine proteinases
Superfamily: Cysteine proteinases
Family: Transglutaminase core

Phyre2

PDB 1wc9 chain A

Region: 1230 - 1299
Aligned: 65
Modelled: 70
Confidence: 27.0%
Identity: 22%
Fold: Ligand-binding domain in the NO signalling and Golgi transport
Superfamily: Ligand-binding domain in the NO signalling and Golgi transport
Family: TRAPP components

Phyre2

PDB 3e5z chain A

Region: 430 - 707
Aligned: 256
Modelled: 262
Confidence: 26.8%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative gluconolactonase;
PDBTitle: x-ray structure of the putative gluconolactonase in protein family2 pf08450. northeast structural genomics consortium target drr130.

Phyre2

PDB 1m3y chain A domain 2

Region: 1239 - 1297
Aligned: 41
Modelled: 42
Confidence: 26.1%
Identity: 29%
Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily: Group II dsDNA viruses VP
Family: Major capsid protein vp54

Phyre2

PDB 3msw chain A

Region: 936 - 986
Aligned: 35
Modelled: 35
Confidence: 24.3%
Identity: 17%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a protein with unknown function (bf3112) from2 bacteroides fragilis nctc 9343 at 1.90 a resolution

Phyre2

PDB 2cfh chain A

Region: 1243 - 1299
Aligned: 52
Modelled: 57
Confidence: 23.9%
Identity: 25%
PDB header:transport
Chain: A: PDB Molecule:trafficking protein particle complex subunit 3;
PDBTitle: structure of the bet3-tpc6b core of trapp

Phyre2

PDB 1rz2 chain A

Region: 1315 - 1399
Aligned: 79
Modelled: 79
Confidence: 22.9%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein ba4783;
PDBTitle: 1.6a crystal structure of the protein ba4783/q81l49 (similar to2 sortase b) from bacillus anthracis.

Phyre2

PDB 3ifz chain A

Region: 1352 - 1398
Aligned: 36
Modelled: 47
Confidence: 22.7%
Identity: 25%
PDB header:isomerase
Chain: A: PDB Molecule:dna gyrase subunit a;
PDBTitle: crystal structure of the first part of the mycobacterium tuberculosis2 dna gyrase reaction core: the breakage and reunion domain at 2.7 a3 resolution

Phyre2

PDB 2x12 chain A

Region: 1158 - 1183
Aligned: 26
Modelled: 26
Confidence: 22.4%
Identity: 27%
PDB header:cell adhesion
Chain: A: PDB Molecule:fimbriae-associated protein fap1;
PDBTitle: ph-induced modulation of streptococcus parasanguinis2 adhesion by fap1 fimbriae

Phyre2

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	S	G	K	P	A	A	R	Q	G	D	M	T	Q	Y	G	G	P	I	V	Q	G	S	A	G	V	R	I	G	A	P	T	G	V	A	C	S	V	C	P	G	G	M	T	S	G	N	P	V	N	P	L	L	G	A	K	V	L	P	G
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?			?	?		?	?	?	?	?		?	?	?	?	?	?	?	?				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	E	T	D	L	A	L	P	G	P	L	P	F	I	L	S	R	T	Y	S	S	Y	R	T	K	T	P	A	P	V	G	V	F	G	P	G	W	K	A	P	S	D	I	R	L	Q	L	R	D	D	G	L	I	L	N	D	N	G	G	R	S
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	I	H	F	E	P	L	L	P	G	E	A	V	Y	S	R	S	E	S	M	W	L	V	R	G	G	K	A	A	Q	P	D	G	H	T	L	A	R	L	W	G	A	L	P	P	D	I	R	L	S	P	H	L	Y	L	A	T	N	S	A	Q
Secondary structure
SS confidence
Disorder																		?																									?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	G	P	W	W	I	L	G	W	S	E	R	V	P	G	A	E	D	V	L	P	A	P	L	P	P	Y	R	V	L	T	G	M	A	D	R	F	G	R	T	L	T	Y	R	R	E	A	A	G	D	L	A	G	E	I	T	G	V	T	D	G
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	A	G	R	E	F	R	L	V	L	T	T	Q	A	Q	R	A	E	E	A	R	T	S	S	L	S	S	S	D	S	S	R	P	L	S	A	S	A	F	P	D	T	L	P	G	T	E	Y	G	P	D	R	G	I	R	L	S	A	V	W	L
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	M	H	D	P	A	Y	P	E	S	L	P	A	A	P	L	V	R	Y	T	Y	T	E	A	G	E	L	L	A	V	Y	D	R	S	N	T	Q	V	R	A	F	T	Y	D	A	Q	H	P	G	R	M	V	A	H	R	Y	A	G	R	P	E
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	M	R	Y	R	Y	D	D	T	G	R	V	V	E	Q	L	N	P	A	G	L	S	Y	R	Y	L	Y	E	Q	D	R	I	T	V	T	D	S	L	N	R	R	E	V	L	H	T	E	G	G	A	G	L	K	R	V	V	K	K	E	L	A
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	D	G	S	V	T	R	S	G	Y	D	A	A	G	R	L	T	A	Q	T	D	A	A	G	R	R	T	E	Y	G	L	N	V	V	S	G	D	I	T	D	I	T	T	P	D	G	R	E	T	K	F	Y	Y	N	D	G	N	Q	L	T	A
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	V	V	S	P	D	G	L	E	S	R	R	E	Y	D	E	P	G	R	L	V	S	E	T	S	R	S	G	E	T	V	R	Y	R	Y	D	D	A	H	S	E	L	P	A	T	T	T	D	A	T	G	S	T	R	Q	M	T	W	S	R	Y
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	G	Q	L	L	A	F	T	D	C	S	G	Y	Q	T	R	Y	E	Y	D	R	F	G	Q	M	T	A	V	H	R	E	E	G	I	S	L	Y	R	R	Y	D	N	R	G	R	L	T	S	V	K	D	A	Q	G	R	E	T	R	Y	E	Y
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	N	A	A	G	D	L	T	A	V	I	T	P	D	G	N	R	S	E	T	Q	Y	D	A	W	G	K	A	V	S	T	T	Q	G	G	L	T	R	S	M	E	Y	D	A	A	G	R	V	I	S	L	T	N	E	N	G	S	H	S	V	F
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	S	Y	D	A	L	D	R	L	V	Q	Q	G	G	F	D	G	R	T	Q	R	Y	H	Y	D	L	T	G	K	L	T	Q	S	E	D	E	G	L	V	I	L	W	Y	Y	D	E	S	D	R	I	T	H	R	T	V	N	G	E	P	A	E
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	Q	W	Q	Y	D	G	H	G	W	L	T	D	I	S	H	L	S	E	G	H	R	V	A	V	H	Y	G	Y	D	D	K	G	R	L	T	G	E	C	Q	T	V	E	N	P	E	T	G	E	L	L	W	Q	H	E	T	K	H	A	Y	N
Secondary structure
SS confidence
Disorder																?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	E	Q	G	L	A	N	R	V	T	P	D	S	L	P	P	V	E	W	L	T	Y	G	S	G	Y	L	A	G	M	K	L	G	G	T	P	L	V	E	Y	T	R	D	R	L	H	R	E	T	V	R	S	F	G	S	M	A	G	S	N	A
Secondary structure
SS confidence
Disorder																																																						?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	A	Y	E	L	T	S	T	Y	T	P	A	G	Q	L	Q	S	Q	H	L	N	S	L	V	Y	D	R	D	Y	G	W	S	D	N	G	D	L	V	R	I	S	G	P	R	Q	T	R	E	Y	G	Y	S	A	T	G	R	L	E	S	V	R
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	T	L	A	P	D	L	D	I	R	I	P	Y	A	T	D	P	A	G	N	R	L	P	D	P	E	L	H	P	D	S	T	L	T	V	W	P	D	N	R	I	A	E	D	A	H	Y	V	Y	R	H	D	E	Y	G	R	L	T	E	K	T
Secondary structure
SS confidence
Disorder		?																						?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	D	R	I	P	A	G	V	I	R	T	D	D	E	R	T	H	H	Y	H	Y	D	S	Q	H	R	L	V	F	Y	T	R	I	Q	H	G	E	P	L	V	E	S	R	Y	L	Y	D	P	L	G	R	R	M	A	K	R	V	W	R	R	E
Secondary structure
SS confidence
Disorder		?	?		?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
Sequence	R	D	L	T	G	W	M	S	L	S	R	K	P	E	V	T	W	Y	G	W	D	G	D	R	L	T	T	V	Q	T	D	T	T	R	I	Q	T	V	Y	E	P	G	S	F	T	P	L	I	R	V	E	T	E	N	G	E	R	E	K	A
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140
Sequence	Q	R	R	S	L	A	E	T	L	Q	Q	E	G	S	E	N	G	H	G	V	V	F	P	A	E	L	V	R	L	L	D	R	L	E	E	E	I	R	A	D	R	V	S	S	E	S	R	A	W	L	A	Q	C	G	L	T	V	E	Q	L
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200
Sequence	A	R	Q	V	E	P	E	Y	T	P	A	R	K	A	H	L	Y	H	C	D	H	R	G	L	P	L	A	L	I	S	E	D	G	N	T	A	W	S	A	E	Y	D	E	W	G	N	Q	L	N	E	E	N	P	H	H	V	Y	Q	P	Y
Secondary structure
SS confidence
Disorder				?	?																																													?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	R	L	P	G	Q	Q	H	D	E	E	S	G	L	Y	Y	N	R	H	R	Y	Y	D	P	L	Q	G	R	Y	I	T	Q	D	P	M	G	L	K	G	G	W	N	L	Y	Q	Y	P	L	N	P	L	Q	Q	I	D	P	M	G	L	L	Q
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320
Sequence	T	W	D	D	A	R	S	G	A	C	T	G	G	V	C	G	V	L	S	R	I	I	G	P	S	K	F	D	S	T	A	D	A	A	L	D	A	L	K	E	T	Q	N	R	S	L	C	N	D	M	E	Y	S	G	I	V	C	K	D	T
Secondary structure
SS confidence
Disorder																	?	?		?	?	?	?	?	?	?	?	?																																?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380
Sequence	N	G	K	Y	F	A	S	K	A	E	T	D	N	L	R	K	E	S	Y	P	L	K	R	K	C	P	T	G	T	D	R	V	A	A	Y	H	T	H	G	A	D	S	H	G	D	Y	V	D	E	F	F	S	S	S	D	K	N	L	V	R
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?				?	?	?	?		?	?	?																							?	?		?												?					?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400	.	.	.	.	.	.	.	.	.	1410	.	.	.	.	.	.	.	.	.	1420	.	.	.	.	.	.
Sequence	S	K	D	N	N	L	E	A	F	Y	L	A	T	P	D	G	R	F	E	A	L	N	N	K	G	E	Y	I	F	I	R	N	S	V	P	G	L	S	S	V	C	I	P	Y	H	D
Secondary structure
SS confidence
Disorder	?																																								?	?	?	?	?	?
Disorder confidence