Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	H	S	T	E	V	Q	A	K	P	L	F	S	W	K	A	L	G	W	A	L	L	Y	F	W	F	F	S	T	L	L	Q	A	I	I	Y	I	S	G	Y	S	G	T	N	G	I	R	D	S	L	L	F	S	S	L	W	L	I	P	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	L	F	P	K	R	I	K	I	I	A	A	V	I	G	V	V	L	W	A	A	S	L	A	A	L	C	Y	Y	V	I	Y	G	Q	E	F	S	Q	S	V	L	F	V	M	F	E	T	N	T	N	E	A	S	E	Y	L	S	Q	Y	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		S	L	K	I	V	L	I	A	L	A	Y	T	A	V	A	V	L	L	W	T	R	L	R	P	V	Y	I	P	K	P	W	R	Y	V	V	S	F	A	L	L	Y	G	L	I	L	H	P	I	A	M	N	T	F	I	K	N	K	P	F	E
Secondary structure
SS confidence
Disorder																							?	?	?	?	?	?	?	?	?	?																					?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	T	L	D	N	L	A	S	R	M	E	P	A	A	P	W	Q	F	L	T	G	Y	Y	Q	Y	R	Q	Q	L	N	S	L	T	K	L	L	N	E	N	N	A	L	P	P	L	A	N	F	K	D	E	S	G	N	E	P	R	T	L	V
Secondary structure
SS confidence
Disorder		?	?								?		?																	?	?				?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	V	I	G	E	S	T	Q	R	G	R	M	S	L	Y	G	Y	P	R	E	T	T	P	E	L	D	A	L	H	K	T	D	P	N	L	T	V	F	N	N	V	V	T	S	R	P	Y	T	I	E	I	L	Q	Q	A	L	T	F	A	N
Secondary structure
SS confidence
Disorder																															?																									?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	K	N	P	D	L	Y	L	T	Q	P	S	L	M	N	M	M	K	Q	A	G	Y	K	T	F	W	I	T	N	Q	Q	T	M	T	A	R	N	T	M	L	T	V	F	S	R	Q	T	D	K	Q	Y	Y	M	N	Q	Q	R	T	Q	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																																														?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	R	E	Y	D	T	N	V	L	K	P	F	Q	E	V	L	N	D	P	A	P	K	K	L	I	I	V	H	L	L	G	T	H	I	K	Y	K	Y	R	Y	P	E	N	Q	G	K	F	D	G	N	T	D	H	V	P	P	G	L	N	A
Secondary structure
SS confidence
Disorder		?																																																				?	?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		E	E	L	E	S	Y	N	D	Y	D	N	A	N	L	Y	N	D	H	V	V	A	S	L	I	K	D	F	K	A	A	N	P	N	G	F	L	V	Y	F	S	D	H	G	E	E	V	Y	D	T	P	P	H	K	T	Q	G	R	N	E	D
Secondary structure
SS confidence
Disorder		?																																													?		?	?	?	?	?	?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		N	P	T	R	H	M	Y	T	I	P	F	L	L	W	T	S	E	K	W	Q	A	T	H	P	R	D	F	S	Q	D	V	D	R	K	Y	S	L	A	E	L	I	H	T	W	S	D	L	A	G	L	S	Y	D	G	Y	D	P	T	R	S
Secondary structure
SS confidence
Disorder		?		?														?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.
Sequence		V	V	N	P	Q	F	K	E	T	T	R	W	I	G	N	P	Y	K	K	N	A	L	I	D	Y	D	T	L	P	Y	G	D	Q	V	G	N	Q
Secondary structure
SS confidence
Disorder																															?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2w8d chain B Region: 208 - 575 Aligned: 348 Modelled: 360 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis Phyre2 PDB 2w5t chain A Region: 208 - 548 Aligned: 322 Modelled: 341 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. Phyre2 PDB 3lxq chain B Region: 203 - 569 Aligned: 329 Modelled: 349 Confidence: 100.0% Identity: 18% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a Phyre2 PDB 3ed4 chain A Region: 236 - 577 Aligned: 330 Modelled: 338 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli Phyre2 PDB 2qzu chain A Region: 229 - 542 Aligned: 300 Modelled: 311 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 Phyre2 PDB 1fsu chain A Region: 234 - 542 Aligned: 285 Modelled: 306 Confidence: 100.0% Identity: 16% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1hdh chain A Region: 235 - 570 Aligned: 324 Modelled: 332 Confidence: 100.0% Identity: 16% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1auk chain A Region: 235 - 542 Aligned: 279 Modelled: 286 Confidence: 100.0% Identity: 16% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 3b5q chain B Region: 235 - 542 Aligned: 295 Modelled: 304 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution Phyre2 PDB 2vqr chain A Region: 236 - 542 Aligned: 292 Modelled: 302 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily Phyre2 PDB 1p49 chain A Region: 233 - 542 Aligned: 282 Modelled: 288 Confidence: 100.0% Identity: 17% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: Arylsulfatase Phyre2 PDB 1o98 chain A domain 2 Region: 236 - 542 Aligned: 260 Modelled: 279 Confidence: 100.0% Identity: 13% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain Phyre2 PDB 2zkt chain B Region: 236 - 531 Aligned: 264 Modelled: 269 Confidence: 100.0% Identity: 11% PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii Phyre2 PDB 2i09 chain A domain 1 Region: 234 - 543 Aligned: 236 Modelled: 257 Confidence: 99.9% Identity: 18% Fold: Alkaline phosphatase-like Superfamily: Alkaline phosphatase-like Family: DeoB catalytic domain-like Phyre2 PDB 3m8y chain C Region: 235 - 543 Aligned: 254 Modelled: 273 Confidence: 99.9% Identity: 18% PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation Phyre2 PDB 3q3q chain A Region: 227 - 541 Aligned: 279 Modelled: 279 Confidence: 99.9% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 Phyre2 PDB 2gso chain B Region: 235 - 542 Aligned: 256 Modelled: 280 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate Phyre2 PDB 2i09 chain A Region: 234 - 542 Aligned: 261 Modelled: 274 Confidence: 99.9% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans Phyre2 PDB 3szz chain A Region: 233 - 525 Aligned: 257 Modelled: 257 Confidence: 99.9% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate Phyre2 PDB 2xrg chain A Region: 223 - 556 Aligned: 258 Modelled: 271 Confidence: 99.8% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor Phyre2 1 c2w8dB_ 2 c2w5tA_ 3 c3lxqB_ 4 c3ed4A_ 5 c2qzuA_ 6 d1fsua_ 7 d1hdha_ 8 d1auka_ 9 c3b5qB_ 10 c2vqrA_ 11 d1p49a_ 12 d1o98a2 13 c2zktB_ 14 d2i09a1 15 c3m8yC_ 16 c3q3qA_ 17 c2gsoB_ 18 c2i09A_ 19 c3szzA_ 20 c2xrgA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2w8dB_ 100.0 15 PDB header:transferase Chain: B: PDB Molecule:processed glycerol phosphate lipoteichoic acid synthase 2; PDBTitle: distinct and essential morphogenic functions for wall- and2 lipo-teichoic acids in bacillus subtilis 2 c2w5tA_ 100.0 15 PDB header:transferase Chain: A: PDB Molecule:processed glycerol phosphate lipoteichoic acid PDBTitle: structure-based mechanism of lipoteichoic acid synthesis by2 staphylococcus aureus ltas. 3 c3lxqB_ 100.0 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp1736; PDBTitle: the crystal structure of a protein in the alkaline2 phosphatase superfamily from vibrio parahaemolyticus to3 1.95a 4 c3ed4A_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:arylsulfatase; PDBTitle: crystal structure of putative arylsulfatase from escherichia coli 5 c2qzuA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of the putative sulfatase yidj from bacteroides2 fragilis. northeast structural genomics consortium target bfr123 6 d1fsua_ 100.0 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 7 d1hdha_ 100.0 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 8 d1auka_ 100.0 16 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 9 c3b5qB_ 100.0 15 PDB header:hydrolase Chain: B: PDB Molecule:putative sulfatase yidj; PDBTitle: crystal structure of a putative sulfatase (np_810509.1)2 from bacteroides thetaiotaomicron vpi-5482 at 2.40 a3 resolution 10 c2vqrA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:putative sulfatase; PDBTitle: crystal structure of a phosphonate monoester hydrolase2 from rhizobium leguminosarum: a new member of the3 alkaline phosphatase superfamily 11 d1p49a_ 100.0 17 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Arylsulfatase 12 d1o98a2 100.0 13 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, catalytic domain 13 c2zktB_ 100.0 11 PDB header:isomerase Chain: B: PDB Molecule:2,3-bisphosphoglycerate-independent phosphoglycerate PDBTitle: structure of ph0037 protein from pyrococcus horikoshii 14 d2i09a1 99.9 18 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:DeoB catalytic domain-like 15 c3m8yC_ 99.9 18 PDB header:isomerase Chain: C: PDB Molecule:phosphopentomutase; PDBTitle: phosphopentomutase from bacillus cereus after glucose-1,6-bisphosphate2 activation 16 c3q3qA_ 99.9 21 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: crystal structure of spap: an novel alkaline phosphatase from2 bacterium sphingomonas sp. strain bsar-1 17 c2gsoB_ 99.9 18 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase-nucleotide pyrophosphatase; PDBTitle: structure of xac nucleotide2 pyrophosphatase/phosphodiesterase in complex with vanadate 18 c2i09A_ 99.9 15 PDB header:isomerase Chain: A: PDB Molecule:phosphopentomutase; PDBTitle: crystal structure of putative phosphopentomutase from streptococcus2 mutans 19 c3szzA_ 99.9 14 PDB header:hydrolase Chain: A: PDB Molecule:phosphonoacetate hydrolase; PDBTitle: crystal structure of phosphonoacetate hydrolase from sinorhizobium2 meliloti 1021 in complex with acetate 20 c2xrgA_ 99.8 17 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 21 c2xr9A_ not modelled 99.8 18 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 22 d1ei6a_ not modelled 99.8 15 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Phosphonoacetate hydrolase 23 c1o98A_ not modelled 99.6 16 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 24 c3igzB_ not modelled 99.6 14 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 25 c2d1gB_ not modelled 99.3 13 PDB header:hydrolase Chain: B: PDB Molecule:acid phosphatase; PDBTitle: structure of francisella tularensis acid phosphatase a (acpa) bound to2 orthovanadate 26 c2iucB_ not modelled 99.1 12 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: structure of alkaline phosphatase from the antarctic2 bacterium tab5 27 d1y6va1 not modelled 98.9 14 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 28 c2w0yB_ not modelled 98.8 14 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 29 c1ew2A_ not modelled 98.8 15 PDB header:hydrolase Chain: A: PDB Molecule:phosphatase; PDBTitle: crystal structure of a human phosphatase 30 c2x98A_ not modelled 98.8 14 PDB header:hydrolase Chain: A: PDB Molecule:alkaline phosphatase; PDBTitle: h.salinarum alkaline phosphatase 31 d1zeda1 not modelled 98.8 15 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 32 d1k7ha_ not modelled 98.7 15 Fold:Alkaline phosphatase-like Superfamily:Alkaline phosphatase-like Family:Alkaline phosphatase 33 c3e2dB_ not modelled 98.5 13 PDB header:hydrolase Chain: B: PDB Molecule:alkaline phosphatase; PDBTitle: the 1.4 a crystal structure of the large and cold-active2 vibrio sp. alkaline phosphatase 34 c3a52A_ not modelled 98.5 16 PDB header:hydrolase Chain: A: PDB Molecule:cold-active alkaline phosphatase; PDBTitle: crystal structure of cold-active alkailne phosphatase from2 psychrophile shewanella sp. 35 c3iddA_ not modelled 90.7 18 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: cofactor-independent phosphoglycerate mutase from2 thermoplasma acidophilum dsm 1728 36 d1s1qa_ not modelled 71.3 15 Fold:UBC-like Superfamily:UBC-like Family:UEV domain 37 d1b4ub_ not modelled 65.1 12 Fold:Phosphorylase/hydrolase-like Superfamily:LigB-like Family:LigB-like 38 c2xokG_ not modelled 46.1 22 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: refined structure of yeast f1c10 atpase complex to 3 a2 resolution 39 c3bd0D_ not modelled 44.9 19 PDB header:peptide binding protein Chain: D: PDB Molecule:protein memo1; PDBTitle: crystal structure of memo, form ii 40 c3ib7A_ not modelled 37.5 18 PDB header:hydrolase Chain: A: PDB Molecule:icc protein; PDBTitle: crystal structure of full length rv0805 41 d3c9fa2 not modelled 36.8 20 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 42 d1usha2 not modelled 35.6 19 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 43 d1j33a_ not modelled 35.5 27 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 44 d1l5oa_ not modelled 32.5 38 Fold:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Superfamily:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) Family:Nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) 45 c3uoaB_ not modelled 29.5 17 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:mucosa-associated lymphoid tissue lymphoma translocation PDBTitle: crystal structure of the malt1 paracaspase (p21 form) 46 d1xo1a2 not modelled 29.1 16 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 47 c2hy1A_ not modelled 21.9 21 PDB header:hydrolase Chain: A: PDB Molecule:rv0805; PDBTitle: crystal structure of rv0805 48 d2hy1a1 not modelled 21.9 21 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 49 d2z1aa2 not modelled 21.5 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain 50 c3e4cB_ not modelled 19.8 10 PDB header:hydrolase Chain: B: PDB Molecule:caspase-1; PDBTitle: procaspase-1 zymogen domain crystal strucutre 51 c3bijC_ not modelled 19.2 32 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein gsu0716; PDBTitle: crystal structure of protein gsu0716 from geobacter2 sulfurreducens. northeast structural genomics target gsr13 52 d1ssna_ not modelled 16.1 12 Fold:beta-Grasp (ubiquitin-like) Superfamily:Staphylokinase/streptokinase Family:Staphylokinase/streptokinase 53 d2jdig1 not modelled 14.8 15 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 54 c1oidA_ not modelled 14.7 19 PDB header:hydrolase Chain: A: PDB Molecule:protein usha; PDBTitle: 5'-nucleotidase (e. coli) with an engineered disulfide2 bridge (s228c, p513c) 55 c2dfjA_ not modelled 13.9 13 PDB header:hydrolase Chain: A: PDB Molecule:diadenosinetetraphosphatase; PDBTitle: crystal structure of the diadenosine tetraphosphate2 hydrolase from shigella flexneri 2a 56 d1tfra2 not modelled 13.6 32 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 57 d2hrca1 not modelled 13.0 34 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 58 c2w6jG_ not modelled 12.9 15 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma, mitochondrial; PDBTitle: low resolution structures of bovine mitochondrial f1-atpase2 during controlled dehydration: hydration state 5. 59 c2rpaA_ not modelled 12.3 24 PDB header:hydrolase Chain: A: PDB Molecule:katanin p60 atpase-containing subunit a1; PDBTitle: the solution structure of n-terminal domain of microtubule severing2 enzyme 60 c2zqeA_ not modelled 12.1 12 PDB header:dna binding protein Chain: A: PDB Molecule:muts2 protein; PDBTitle: crystal structure of the smr domain of thermus thermophilus muts2 61 d3d03a1 not modelled 12.1 17 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:GpdQ-like 62 d1yp2a2 not modelled 11.4 7 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:glucose-1-phosphate thymidylyltransferase 63 c2jcmA_ not modelled 10.8 19 PDB header:hydrolase Chain: A: PDB Molecule:cytosolic purine 5'-nucleotidase; PDBTitle: crystal structure of human cytosolic 5'-nucleotidase ii in2 complex with beryllium trifluoride 64 c3c9fB_ not modelled 10.4 20 PDB header:hydrolase Chain: B: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase from candida albicans sc5314 65 c3oaaO_ not modelled 10.3 17 PDB header:hydrolase/transport protein Chain: O: PDB Molecule:atp synthase gamma chain; PDBTitle: structure of the e.coli f1-atp synthase inhibited by subunit epsilon 66 d2hkja2 not modelled 10.2 20 Fold:Ribosomal protein S5 domain 2-like Superfamily:Ribosomal protein S5 domain 2-like Family:DNA gyrase/MutL, second domain 67 c2qe7G_ not modelled 9.9 33 PDB header:hydrolase Chain: G: PDB Molecule:atp synthase subunit gamma; PDBTitle: crystal structure of the f1-atpase from the thermoalkaliphilic2 bacterium bacillus sp. ta2.a1 68 c2xmoB_ not modelled 9.4 18 PDB header:hydrolase Chain: B: PDB Molecule:lmo2642 protein; PDBTitle: the crystal structure of lmo2642 69 c3e20C_ not modelled 9.4 24 PDB header:translation Chain: C: PDB Molecule:eukaryotic peptide chain release factor subunit 1; PDBTitle: crystal structure of s.pombe erf1/erf3 complex 70 c2z1aA_ not modelled 9.1 16 PDB header:hydrolase Chain: A: PDB Molecule:5'-nucleotidase; PDBTitle: crystal structure of 5'-nucleotidase precursor from thermus2 thermophilus hb8 71 c3rsbB_ not modelled 9.1 8 PDB header:transferase Chain: B: PDB Molecule:adenosylcobinamide-phosphate guanylyltransferase; PDBTitle: structure of the archaeal gtp:adocbi-p guanylyltransferase (coby) from2 methanocaldococcus jannaschii 72 d1uzdc1 not modelled 9.1 19 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 73 d1g5ba_ not modelled 8.9 13 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:Protein serine/threonine phosphatase 74 c2we9A_ not modelled 8.9 11 PDB header:unknown function Chain: A: PDB Molecule:moba-related protein; PDBTitle: crystal structure of rv0371c from mycobacterium2 tuberculosis h37rv 75 c3t9aA_ not modelled 8.9 14 PDB header:transferase Chain: A: PDB Molecule:inositol pyrophosphate kinase; PDBTitle: crystal structure of the catalytic domain of human diphosphoinositol2 pentakisphosphate kinase 2 (ppip5k2) in complex with amppnp at ph 7.0 76 d1uf3a_ not modelled 8.7 4 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:TT1561-like 77 d1fs0g_ not modelled 8.7 19 Fold:Pyruvate kinase C-terminal domain-like Superfamily:ATP synthase (F1-ATPase), gamma subunit Family:ATP synthase (F1-ATPase), gamma subunit 78 d1tg7a4 not modelled 8.5 33 Fold:Glycosyl hydrolase domain Superfamily:Glycosyl hydrolase domain Family:Beta-galactosidase LacA, domain 2 79 d2saka_ not modelled 8.5 12 Fold:beta-Grasp (ubiquitin-like) Superfamily:Staphylokinase/streptokinase Family:Staphylokinase/streptokinase 80 c2ihnA_ not modelled 8.3 28 PDB header:hydrolase/dna Chain: A: PDB Molecule:ribonuclease h; PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate 81 d1xfla_ not modelled 8.2 0 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 82 d1dt9a3 not modelled 8.1 35 Fold:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Superfamily:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Family:N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 83 d1o7fa2 not modelled 8.1 14 Fold:Double-stranded beta-helix Superfamily:cAMP-binding domain-like Family:cAMP-binding domain 84 d1ej7s_ not modelled 8.0 13 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 85 d1tzfa_ not modelled 8.0 11 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:Cytidylytransferase 86 c2f9tB_ not modelled 7.9 14 PDB header:transferase Chain: B: PDB Molecule:pantothenate kinase; PDBTitle: structure of the type iii coaa from pseudomonas aeruginosa 87 d1szpb1 not modelled 7.9 14 Fold:SAM domain-like Superfamily:Rad51 N-terminal domain-like Family:DNA repair protein Rad51, N-terminal domain 88 c2qjcA_ not modelled 7.9 17 PDB header:hydrolase Chain: A: PDB Molecule:diadenosine tetraphosphatase, putative; PDBTitle: crystal structure of a putative diadenosine tetraphosphatase 89 c2qh5B_ not modelled 7.8 11 PDB header:isomerase Chain: B: PDB Molecule:mannose-6-phosphate isomerase; PDBTitle: crystal structure of mannose-6-phosphate isomerase from helicobacter2 pylori 90 d2b8ea1 not modelled 7.8 9 Fold:HAD-like Superfamily:HAD-like Family:Meta-cation ATPase, catalytic domain P 91 c3zu0A_ not modelled 7.6 14 PDB header:hydrolase Chain: A: PDB Molecule:nad nucleotidase; PDBTitle: structure of haemophilus influenzae nad nucleotidase (nadn) 92 c3cagF_ not modelled 7.6 25 PDB header:dna binding protein Chain: F: PDB Molecule:arginine repressor; PDBTitle: crystal structure of the oligomerization domain hexamer of the2 arginine repressor protein from mycobacterium tuberculosis in complex3 with 9 arginines. 93 d1eh9a3 not modelled 7.5 12 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 94 d1gp6a_ not modelled 7.4 11 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:Penicillin synthase-like 95 d8ruci_ not modelled 7.3 15 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 96 d1b4ba_ not modelled 7.3 13 Fold:DCoH-like Superfamily:C-terminal domain of arginine repressor Family:C-terminal domain of arginine repressor 97 d1w9ya1 not modelled 7.3 9 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:Penicillin synthase-like 98 c2wawA_ not modelled 7.2 11 PDB header:unknown function Chain: A: PDB Molecule:moba relate protein; PDBTitle: crystal structure of mycobacterium tuberculosis rv0371c2 homolog from mycobacterium sp. strain jc1 99 c3sirD_ not modelled 7.1 14 PDB header:hydrolase Chain: D: PDB Molecule:caspase; PDBTitle: crystal structure of drice

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0