Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	E	S	N	S	R	R	E	F	L	S	Q	S	G	K	M	V	T	A	A	A	L	F	G	T	S	V	P	L	A	H	A	A	V	A	G	T	L	N	C	E	A	N	N	T	M	K	I	T	D	P	H	Y	Y	L	D	N	V	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?								?	?	?	?								?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	E	T	G	F	D	Y	E	N	G	V	A	V	Q	T	R	T	A	R	Q	T	V	E	I	Q	D	G	K	I	V	A	L	R	E	N	K	L	H	P	D	A	T	L	P	H	Y	D	A	G	G	K	L	M	L	P	T	T	R	D	M
Secondary structure
SS confidence
Disorder																																					?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	I	H	L	D	K	T	F	Y	G	G	P	W	R	S	L	N	R	P	A	G	T	T	I	Q	D	M	I	K	L	E	Q	K	M	L	P	E	L	Q	P	Y	T	Q	E	R	A	E	K	L	I	D	L	L	Q	S	K	G	T	T	I
Secondary structure
SS confidence
Disorder											?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	R	S	H	C	N	I	E	P	V	S	G	L	K	N	L	Q	N	L	Q	A	V	L	A	R	R	Q	A	G	F	E	C	E	I	V	A	F	P	Q	H	G	L	L	L	S	K	S	E	P	L	M	R	E	A	M	Q	A	G	A	H
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Y	V	G	G	L	D	P	T	S	V	D	G	A	M	E	K	S	L	D	T	M	F	Q	I	A	L	D	Y	D	K	G	V	D	I	H	L	H	E	T	T	P	A	G	V	A	A	I	N	Y	M	V	E	T	V	E	K	T	P	Q	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		K	G	K	L	T	I	S	H	A	F	A	L	A	T	L	N	E	Q	Q	V	D	E	L	A	N	R	M	V	V	Q	Q	I	S	I	A	S	T	V	P	I	G	T	L	H	M	P	L	K	Q	L	H	D	K	G	V	K	V	M	T	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		T	D	S	V	I	D	H	W	S	P	Y	G	L	G	D	M	L	E	K	A	N	L	Y	A	Q	L	Y	I	R	P	N	E	Q	N	L	S	R	S	L	F	L	A	T	G	D	V	L	P	L	N	E	K	G	E	R	V	W	P	K	A
Secondary structure
SS confidence
Disorder																																																						?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460
Sequence		Q	D	D	A	S	F	V	L	V	D	A	S	C	S	A	E	A	V	A	R	I	S	P	R	T	A	T	F	H	K	G	Q	L	V	W	G	S	V	A	G
Secondary structure
SS confidence
Disorder																																					?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2qt3 chain A Region: 53 - 457 Aligned: 390 Modelled: 397 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase; PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn Phyre2 PDB 1r9y chain A Region: 55 - 460 Aligned: 390 Modelled: 394 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:cytosine deaminase; PDBTitle: bacterial cytosine deaminase d314a mutant. Phyre2 PDB 3hpa chain B Region: 52 - 457 Aligned: 385 Modelled: 406 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea Phyre2 PDB 3lnp chain A Region: 50 - 457 Aligned: 389 Modelled: 392 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465; PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica Phyre2 PDB 2i9u chain A Region: 52 - 455 Aligned: 391 Modelled: 404 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:cytosine/guanine deaminase related protein; PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site Phyre2 PDB 3lsb chain A Region: 53 - 457 Aligned: 396 Modelled: 405 Confidence: 100.0% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:triazine hydrolase; PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin Phyre2 PDB 1p1m chain A Region: 55 - 455 Aligned: 368 Modelled: 388 Confidence: 100.0% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tm0936; PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine Phyre2 PDB 2q09 chain A Region: 53 - 456 Aligned: 380 Modelled: 388 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid Phyre2 PDB 2gok chain A Region: 52 - 455 Aligned: 381 Modelled: 391 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution Phyre2 PDB 3e0l chain B Region: 51 - 457 Aligned: 390 Modelled: 407 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase Phyre2 PDB 2bb0 chain A Region: 53 - 455 Aligned: 383 Modelled: 403 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis Phyre2 PDB 2paj chain A Region: 52 - 455 Aligned: 360 Modelled: 385 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/guanine deaminase; PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea Phyre2 PDB 3gnh chain A Region: 54 - 455 Aligned: 365 Modelled: 387 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672; PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine. Phyre2 PDB 1gkp chain D Region: 53 - 457 Aligned: 384 Modelled: 386 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 Phyre2 PDB 2ftw chain A Region: 51 - 457 Aligned: 366 Modelled: 378 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum Phyre2 PDB 2gse chain C Region: 52 - 455 Aligned: 385 Modelled: 396 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 Phyre2 PDB 3hm7 chain A Region: 53 - 457 Aligned: 382 Modelled: 397 Confidence: 100.0% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 Phyre2 PDB 3mdu chain A Region: 52 - 460 Aligned: 381 Modelled: 401 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase; PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate Phyre2 PDB 3be7 chain B Region: 52 - 455 Aligned: 364 Modelled: 394 Confidence: 100.0% Identity: 12% PDB header:hydrolase Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase; PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase Phyre2 PDB 2ood chain A Region: 54 - 455 Aligned: 392 Modelled: 402 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:blr3880 protein; PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum Phyre2 PDB 4ubp chain C domain 1 Region: 33 - 114 Aligned: 72 Modelled: 72 Confidence: 95.7% Identity: 19% Fold: Composite domain of metallo-dependent hydrolases Superfamily: Composite domain of metallo-dependent hydrolases Family: alpha-Subunit of urease Phyre2 PDB 2e76 chain D Region: 4 - 52 Aligned: 49 Modelled: 49 Confidence: 77.3% Identity: 14% PDB header:photosynthesis Chain: D: PDB Molecule:cytochrome b6-f complex iron-sulfur subunit; PDBTitle: crystal structure of the cytochrome b6f complex with tridecyl-2 stigmatellin (tds) from m.laminosus Phyre2 1 c2qt3A_ 2 c1r9yA_ 3 c3hpaB_ 4 c3lnpA_ 5 c2i9uA_ 6 c3lsbA_ 7 c1p1mA_ 8 c2q09A_ 9 c2gokA_ 10 c3e0lB_ 11 c2bb0A_ 12 c2pajA_ 13 c3gnhA_ 14 c1gkpD_ 15 c2ftwA_ 16 c2gseC_ 17 c3hm7A_ 18 c3mduA_ 19 c3be7B_ 20 c2oodA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 d4ubpc1 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 c2e76D_ 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2qt3A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:n-isopropylammelide isopropyl amidohydrolase; PDBTitle: crystal structure of n-isopropylammelide isopropylaminohydrolase atzc2 from pseudomonas sp. strain adp complexed with zn 2 c1r9yA_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:cytosine deaminase; PDBTitle: bacterial cytosine deaminase d314a mutant. 3 c3hpaB_ 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of an amidohydrolase gi:44264246 from an2 evironmental sample of sargasso sea 4 c3lnpA_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein olei01672_1_465; PDBTitle: crystal structure of amidohydrolase family protein2 olei01672_1_465 from oleispira antarctica 5 c2i9uA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:cytosine/guanine deaminase related protein; PDBTitle: crystal structure of guanine deaminase from c. acetobutylicum with2 bound guanine in the active site 6 c3lsbA_ 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:triazine hydrolase; PDBTitle: crystal structure of the mutant e241q of atrazine chlorohydrolase trzn2 from arthrobacter aurescens tc1 complexed with zinc and ametrin 7 c1p1mA_ 100.0 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tm0936; PDBTitle: structure of thermotoga maritima amidohydrolase tm09362 bound to ni and methionine 8 c2q09A_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of imidazolonepropionase from environmental sample2 with bound inhibitor 3-(2,5-dioxo-imidazolidin-4-yl)-propionic acid 9 c2gokA_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: crystal structure of the imidazolonepropionase from agrobacterium2 tumefaciens at 1.87 a resolution 10 c3e0lB_ 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:guanine deaminase; PDBTitle: computationally designed ammelide deaminase 11 c2bb0A_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:imidazolonepropionase; PDBTitle: structure of imidazolonepropionase from bacillus subtilis 12 c2pajA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:putative cytosine/guanine deaminase; PDBTitle: crystal structure of an amidohydrolase from an environmental sample of2 sargasso sea 13 c3gnhA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:l-lysine, l-arginine carboxypeptidase cc2672; PDBTitle: crystal structure of l-lysine, l-arginine carboxypeptidase cc2672 from2 caulobacter crescentus cb15 complexed with n-methyl phosphonate3 derivative of l-arginine. 14 c1gkpD_ 100.0 12 PDB header:hydrolase Chain: D: PDB Molecule:hydantoinase; PDBTitle: d-hydantoinase (dihydropyrimidinase) from thermus sp. in2 space group c2221 15 c2ftwA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidine amidohydrolase; PDBTitle: crystal structure of dihydropyrimidinase from dictyostelium discoideum 16 c2gseC_ 100.0 12 PDB header:hydrolase Chain: C: PDB Molecule:dihydropyrimidinase-related protein 2; PDBTitle: crystal structure of human dihydropyrimidinease-like 2 17 c3hm7A_ 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:allantoinase; PDBTitle: crystal structure of allantoinase from bacillus halodurans c-125 18 c3mduA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:n-formimino-l-glutamate iminohydrolase; PDBTitle: the structure of n-formimino-l-glutamate iminohydrolase from2 pseudomonas aeruginosa complexed with n-guanidino-l-glutamate 19 c3be7B_ 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:zn-dependent arginine carboxypeptidase; PDBTitle: crystal structure of zn-dependent arginine carboxypeptidase 20 c2oodA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:blr3880 protein; PDBTitle: crystal structure of guanine deaminase from bradyrhizobium japonicum 21 c1gkrA_ not modelled 100.0 12 PDB header:hydrolase Chain: A: PDB Molecule:non-atp dependent l-selective hydantoinase; PDBTitle: l-hydantoinase (dihydropyrimidinase) from arthrobacter2 aurescens 22 c3v7pA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase family protein; PDBTitle: crystal structure of amidohydrolase nis_0429 (target efi-500396) from2 nitratiruptor sp. sb155-2 23 c3d6nA_ not modelled 100.0 14 PDB header:hydrolase/transferase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase 24 c2r8cB_ not modelled 100.0 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eaj56179 25 c2vr2A_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: human dihydropyrimidinase 26 c3dc8B_ not modelled 100.0 13 PDB header:hydrolase Chain: B: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from sinorhizobium meliloti 27 c2vunC_ not modelled 100.0 17 PDB header:hydrolase Chain: C: PDB Molecule:enamidase; PDBTitle: the crystal structure of enamidase at 1.9 a resolution - a2 new member of the amidohydrolase superfamily 28 c1k1dF_ not modelled 100.0 14 PDB header:hydrolase Chain: F: PDB Molecule:d-hydantoinase; PDBTitle: crystal structure of d-hydantoinase 29 c2qs8A_ not modelled 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of a xaa-pro dipeptidase with bound2 methionine in the active site 30 c1nfgA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:d-hydantoinase; PDBTitle: structure of d-hydantoinase 31 c2p9bA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:possible prolidase; PDBTitle: crystal structure of putative prolidase from2 bifidobacterium longum 32 c1xrfA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a novel, latent dihydroorotase from aquifex2 aeolicus at 1.7 a resolution 33 c3gipB_ not modelled 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:n-acyl-d-glutamate deacylase; PDBTitle: crystal structure of n-acyl-d-glutamate deacylase from2 bordetella bronchiseptica complexed with zinc, acetate and3 formate ions. 34 c2fvmA_ not modelled 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:dihydropyrimidinase; PDBTitle: crystal structure of dihydropyrimidinase from saccharomyces kluyveri2 in complex with the reaction product n-carbamyl-beta-alanine 35 c3mpgB_ not modelled 100.0 16 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: dihydroorotase from bacillus anthracis 36 c3feqB_ not modelled 100.0 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative amidohydrolase; PDBTitle: crystal structure of uncharacterized protein eah89906 37 c1rjqA_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:d-aminoacylase; PDBTitle: the crystal structure of the d-aminoacylase mutant d366a 38 c2ubpC_ not modelled 100.0 17 PDB header:hydrolase Chain: C: PDB Molecule:protein (urease alpha subunit); PDBTitle: structure of native urease from bacillus pasteurii 39 c2vhlB_ not modelled 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: the three-dimensional structure of the n-acetylglucosamine-2 6-phosphate deacetylase from bacillus subtilis 40 c3griB_ not modelled 100.0 15 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: the crystal structure of a dihydroorotase from staphylococcus aureus 41 c3nqbB_ not modelled 100.0 14 PDB header:hydrolase Chain: B: PDB Molecule:adenine deaminase 2; PDBTitle: crystal structure of adenine deaminase from agrobacterium tumefaciens2 (str. c 58) 42 c2aqoB_ not modelled 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:isoaspartyl dipeptidase; PDBTitle: crystal structure of e. coli isoaspartyl dipeptidase mutant e77q 43 c3e74D_ not modelled 100.0 14 PDB header:hydrolase Chain: D: PDB Molecule:allantoinase; PDBTitle: crystal structure of e. coli allantoinase with iron ions at2 the metal center 44 c2gwnA_ not modelled 100.0 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydroorotase; PDBTitle: the structure of putative dihydroorotase from porphyromonas2 gingivalis. 45 c1e9yB_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:urease subunit beta; PDBTitle: crystal structure of helicobacter pylori urease in complex with2 acetohydroxamic acid 46 c2p50C_ not modelled 100.0 11 PDB header:hydrolase Chain: C: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetyl-d-glucosamine-6-phosphate deacetylase2 liganded with zn 47 c1fwcC_ not modelled 100.0 15 PDB header:hydrolase Chain: C: PDB Molecule:urease; PDBTitle: klebsiella aerogenes urease, c319a variant at ph 8.5 48 c2z00A_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of dihydroorotase from thermus thermophilus 49 c3ooqC_ not modelled 100.0 15 PDB header:hydrolase Chain: C: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of amidohydrolase from thermotoga maritima msb8 50 c3etkA_ not modelled 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus furiosus 51 c3egjA_ not modelled 100.0 13 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: n-acetylglucosamine-6-phosphate deacetylase from vibrio cholerae. 52 c2imrA_ not modelled 100.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dr_0824; PDBTitle: crystal structure of amidohydrolase dr_0824 from2 deinococcus radiodurans 53 c3ighX_ not modelled 100.0 15 PDB header:hydrolase Chain: X: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from pyrococcus horikoshii ot3 54 c3la4A_ not modelled 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:urease; PDBTitle: crystal structure of the first plant urease from jack bean (canavalia2 ensiformis) 55 c2icsA_ not modelled 100.0 12 PDB header:hydrolase Chain: A: PDB Molecule:adenine deaminase; PDBTitle: crystal structure of an adenine deaminase 56 c2ogjB_ not modelled 100.0 12 PDB header:hydrolase Chain: B: PDB Molecule:dihydroorotase; PDBTitle: crystal structure of a dihydroorotase 57 c1o12B_ not modelled 100.0 13 PDB header:hydrolase Chain: B: PDB Molecule:n-acetylglucosamine-6-phosphate deacetylase; PDBTitle: crystal structure of n-acetylglucosamine-6-phosphate2 deacetylase (tm0814) from thermotoga maritima at 2.5 a3 resolution 58 d1ra0a2 not modelled 99.9 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Cytosine deaminase catalytic domain 59 d2uz9a2 not modelled 99.9 20 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 60 d2i9ua2 not modelled 99.8 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 61 d1p1ma2 not modelled 99.8 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 62 d2imra2 not modelled 99.7 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:DR0824-like 63 d2ooda2 not modelled 99.7 18 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 64 d2bb0a2 not modelled 99.7 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 65 c3msrA_ not modelled 99.7 12 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolases; PDBTitle: the crystal structure of an amidohydrolase from mycoplasma synoviae 66 d2puza2 not modelled 99.6 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 67 d2q09a2 not modelled 99.6 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 68 d2paja2 not modelled 99.6 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 69 d4ubpc2 not modelled 99.6 21 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:alpha-subunit of urease, catalytic domain 70 d1gkpa2 not modelled 99.5 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 71 d2p9ba1 not modelled 99.5 18 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Imidazolonepropionase-like 72 d2qs8a2 not modelled 99.5 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 73 d1yrra1 not modelled 99.5 18 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:N-acetylglucosamine-6-phosphate deacetylase, NagA 74 d2p9ba2 not modelled 99.5 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Imidazolonepropionase-like 75 d1kcxa2 not modelled 99.5 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 76 d3be7a2 not modelled 99.4 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 77 c3ggmB_ not modelled 99.4 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bt9727_2919; PDBTitle: crystal structure of bt9727_2919 from bacillus2 thuringiensis subsp. northeast structural genomics target3 bur228b 78 c3ou8B_ not modelled 99.4 12 PDB header:hydrolase Chain: B: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 79 d2r8ca2 not modelled 99.4 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 80 d1ejxc1 not modelled 99.4 19 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:alpha-Subunit of urease 81 d1onwa1 not modelled 99.4 15 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Isoaspartyl dipeptidase 82 c3ou8A_ not modelled 99.3 14 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 83 d1e9yb1 not modelled 99.3 20 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:alpha-Subunit of urease 84 d1xrta2 not modelled 99.3 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 85 d2r8ca1 not modelled 99.3 17 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 86 c3pnuA_ not modelled 99.3 12 PDB header:hydrolase Chain: A: PDB Molecule:dihydroorotase; PDBTitle: 2.4 angstrom crystal structure of dihydroorotase (pyrc) from2 campylobacter jejuni. 87 d2ftwa2 not modelled 99.3 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 88 d2fvka1 not modelled 99.3 19 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 89 d1i0da_ not modelled 99.3 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 90 d1ynya2 not modelled 99.3 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 91 d1k1da2 not modelled 99.2 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 92 d2d2ja1 not modelled 99.2 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 93 c1pscA_ not modelled 99.1 12 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta 94 d1nfga2 not modelled 99.0 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 95 d1gkra2 not modelled 99.0 10 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 96 d2eg6a1 not modelled 99.0 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Dihydroorotase 97 d2fvka2 not modelled 99.0 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 98 c3jzeC_ not modelled 99.0 14 PDB header:hydrolase Chain: C: PDB Molecule:dihydroorotase; PDBTitle: 1.8 angstrom resolution crystal structure of dihydroorotase (pyrc)2 from salmonella enterica subsp. enterica serovar typhimurium str. lt2 99 d2ftwa1 not modelled 99.0 23 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 100 c3rysA_ not modelled 98.9 16 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase 1; PDBTitle: the crystal structure of adenine deaminase (aaur1117) from2 arthrobacter aurescens 101 c2zc1A_ not modelled 98.9 12 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: organophosphorus hydrolase from deinococcus radiodurans 102 c3pnzD_ not modelled 98.9 10 PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes 103 d1k1da1 not modelled 98.9 29 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 104 d2icsa2 not modelled 98.8 9 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenine deaminase-like 105 d1vfla1 not modelled 98.8 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 106 d1onwa2 not modelled 98.8 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Isoaspartyl dipeptidase, catalytic domain 107 d1a4ma_ not modelled 98.8 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 108 d1gkpa1 not modelled 98.8 19 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 109 d1ynya1 not modelled 98.8 22 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 110 c3f4cA_ not modelled 98.8 13 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 111 d2amxa1 not modelled 98.7 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 112 d1bf6a_ not modelled 98.7 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 113 d1m7ja1 not modelled 98.7 20 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:D-aminoacylase 114 c2vc7A_ not modelled 98.7 11 PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities 115 d3be7a1 not modelled 98.7 10 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Zn-dependent arginine carboxypeptidase-like 116 d2bb0a1 not modelled 98.6 18 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Imidazolonepropionase-like 117 d1kcxa1 not modelled 98.4 17 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase) 118 d2paja1 not modelled 98.3 17 Fold:Composite domain of metallo-dependent hydrolases Superfamily:Composite domain of metallo-dependent hydrolases Family:SAH/MTA deaminase-like 119 d1m7ja3 not modelled 98.3 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:D-aminoacylase, catalytic domain 120 d1zzma1 not modelled 98.2 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0