Secondary structure and disorder prediction

1

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10

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20

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30

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40

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50

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60

Sequence

M

F

W

L

M

L

L

I

I

S

A

K

M

A

H

S

L

W

R

Y

I

S

F

S

A

E

Y

T

A

V

S

Q

P

V

N

K

P

S

R

V

D

A

K

T

F

D

K

N

D

V

Q

L

I

S

Q

Q

N

W

F

G

Secondary structure

SS confidence

Disorder

?

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?

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?

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?

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?

Disorder confidence

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70

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80

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90

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100

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110

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120

Sequence

K

Y

Q

P

V

A

A

Q

V

K

Q

P

E

P

V

P

V

A

E

T

R

L

N

V

V

L

R

G

I

A

F

G

A

R

P

G

A

V

I

E

E

G

G

K

Q

Q

V

Y

L

Q

G

E

T

L

G

S

H

N

A

V

Secondary structure

SS confidence

Disorder

?

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?

Disorder confidence

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130

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140

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150

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160

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170

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180

Sequence

I

E

E

I

N

R

D

H

V

M

L

R

Y

Q

G

K

I

E

R

L

S

L

A

E

E

E

R

S

T

V

A

V

T

N

K

K

A

V

S

D

E

A

K

Q

A

V

A

E

P

A

V

S

V

P

V

E

I

P

A

A

Secondary structure

SS confidence

Disorder

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Disorder confidence

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190

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200

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210

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220

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230

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240

Sequence

V

R

Q

A

L

A

K

D

P

Q

K

I

F

N

Y

I

Q

L

T

P

V

R

K

E

G

I

V

G

Y

A

A

K

P

G

A

D

R

S

L

F

D

A

S

G

F

K

E

G

D

I

A

I

A

L

N

Q

Q

D

F

T

Secondary structure

SS confidence

Disorder

?

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Disorder confidence

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250

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260

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270

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280

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Sequence

D

P

R

A

M

I

A

L

M

R

Q

L

P

S

M

D

S

I

Q

L

T

V

L

R

K

G

A

R

H

D

I

S

I

A

L

R

Y

R

L

F

C

P

P

Y

W

K

K

S

Secondary structure

SS confidence

Disorder

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Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2i4s chain A domain 1 Region: 176 - 274 Aligned: 99 Modelled: 99 Confidence: 99.8% Identity: 38% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: EpsC C-terminal domain-like Phyre2 PDB 2i6v chain A domain 1 Region: 190 - 275 Aligned: 86 Modelled: 86 Confidence: 99.7% Identity: 41% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: EpsC C-terminal domain-like Phyre2 PDB 3stj chain C Region: 55 - 277 Aligned: 212 Modelled: 223 Confidence: 99.7% Identity: 15% PDB header:hydrolase Chain: C: PDB Molecule:protease degq; PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli Phyre2 PDB 3qo6 chain B Region: 61 - 279 Aligned: 213 Modelled: 219 Confidence: 99.6% Identity: 12% PDB header:photosynthesis Chain: B: PDB Molecule:protease do-like 1, chloroplastic; PDBTitle: crystal structure analysis of the plant protease deg1 Phyre2 PDB 3pv4 chain A Region: 120 - 277 Aligned: 146 Modelled: 158 Confidence: 99.6% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (delta-pdz2 variant) Phyre2 PDB 3pv5 chain B Region: 124 - 277 Aligned: 144 Modelled: 154 Confidence: 99.5% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (n189g/p190g variant) Phyre2 PDB 1lcy chain A Region: 202 - 278 Aligned: 74 Modelled: 77 Confidence: 99.5% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:htra2 serine protease; PDBTitle: crystal structure of the mitochondrial serine protease htra2 Phyre2 PDB 2z9i chain A domain 1 Region: 195 - 277 Aligned: 82 Modelled: 83 Confidence: 99.5% Identity: 12% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: HtrA-like serine proteases Phyre2 PDB 3gds chain A Region: 55 - 274 Aligned: 207 Modelled: 207 Confidence: 99.5% Identity: 11% PDB header:hydrolase/hydrolase activator Chain: A: PDB Molecule:protease degs; PDBTitle: crystal structure of degs h198p/d320a mutant modified by dfp in2 complex with dnrdgnvyyf peptide Phyre2 PDB 1ky9 chain A Region: 124 - 274 Aligned: 145 Modelled: 150 Confidence: 99.4% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:protease do; PDBTitle: crystal structure of degp (htra) Phyre2 PDB 2kl1 chain A Region: 204 - 284 Aligned: 80 Modelled: 81 Confidence: 99.4% Identity: 16% PDB header:protein binding Chain: A: PDB Molecule:ylbl protein; PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c Phyre2 PDB 2p3w chain B Region: 207 - 281 Aligned: 72 Modelled: 75 Confidence: 99.4% Identity: 21% PDB header:protein binding Chain: B: PDB Molecule:probable serine protease htra3; PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv) Phyre2 PDB 1lcy chain A domain 1 Region: 202 - 276 Aligned: 72 Modelled: 75 Confidence: 99.4% Identity: 11% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: HtrA-like serine proteases Phyre2 PDB 3i18 chain A Region: 207 - 278 Aligned: 71 Modelled: 72 Confidence: 99.4% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lmo2051 protein; PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b Phyre2 PDB 2kjp chain A Region: 207 - 286 Aligned: 79 Modelled: 80 Confidence: 99.3% Identity: 14% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ylbl; PDBTitle: solution structure of protein ylbl (bsu15050) from bacillus2 subtilis, northeast structural genomics consortium target3 sr713a Phyre2 PDB 2joa chain A Region: 202 - 276 Aligned: 72 Modelled: 72 Confidence: 99.3% Identity: 18% PDB header:protein binding Chain: A: PDB Molecule:serine protease htra1; PDBTitle: htra1 bound to an optimized peptide: nmr assignment of pdz2 domain and ligand resonances Phyre2 PDB 3oss chain C Region: 79 - 142 Aligned: 64 Modelled: 64 Confidence: 99.3% Identity: 97% PDB header:protein transport Chain: C: PDB Molecule:type 2 secretion system, gspc; PDBTitle: the crystal structure of enterotoxigenic escherichia coli gspc-gspd2 complex from the type ii secretion system Phyre2 PDB 1ky9 chain A domain 1 Region: 207 - 274 Aligned: 68 Modelled: 68 Confidence: 99.3% Identity: 22% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: HtrA-like serine proteases Phyre2 PDB 1fc6 chain A domain 3 Region: 196 - 278 Aligned: 82 Modelled: 83 Confidence: 99.3% Identity: 12% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: Tail specific protease PDZ domain Phyre2 PDB 2hga chain A domain 1 Region: 206 - 274 Aligned: 68 Modelled: 69 Confidence: 99.2% Identity: 10% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: MTH1368 C-terminal domain-like Phyre2 1 d2i4sa1 2 d2i6va1 3 c3stjC_ 4 c3qo6B_ 5 c3pv4A_ 6 c3pv5B_ 7 c1lcyA_ 8 d2z9ia1 9 c3gdsA_ 10 c1ky9A_ 11 c2kl1A_ 12 c2p3wB_ 13 d1lcya1 14 c3i18A_ 15 c2kjpA_ 16 c2joaA_ 17 c3ossC_ 18 d1ky9a1 19 d1fc6a3 20 d2hgaa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2i4sa1 99.8 38 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 2 d2i6va1 99.7 41 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 3 c3stjC_ 99.7 15 PDB header:hydrolase Chain: C: PDB Molecule:protease degq; PDBTitle: crystal structure of the protease + pdz1 domain of degq from2 escherichia coli 4 c3qo6B_ 99.6 12 PDB header:photosynthesis Chain: B: PDB Molecule:protease do-like 1, chloroplastic; PDBTitle: crystal structure analysis of the plant protease deg1 5 c3pv4A_ 99.6 14 PDB header:hydrolase Chain: A: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (delta-pdz2 variant) 6 c3pv5B_ 99.5 16 PDB header:hydrolase Chain: B: PDB Molecule:degq; PDBTitle: structure of legionella fallonii degq (n189g/p190g variant) 7 c1lcyA_ 99.5 11 PDB header:hydrolase Chain: A: PDB Molecule:htra2 serine protease; PDBTitle: crystal structure of the mitochondrial serine protease htra2 8 d2z9ia1 99.5 12 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 9 c3gdsA_ 99.5 11 PDB header:hydrolase/hydrolase activator Chain: A: PDB Molecule:protease degs; PDBTitle: crystal structure of degs h198p/d320a mutant modified by dfp in2 complex with dnrdgnvyyf peptide 10 c1ky9A_ 99.4 17 PDB header:hydrolase Chain: A: PDB Molecule:protease do; PDBTitle: crystal structure of degp (htra) 11 c2kl1A_ 99.4 16 PDB header:protein binding Chain: A: PDB Molecule:ylbl protein; PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c 12 c2p3wB_ 99.4 21 PDB header:protein binding Chain: B: PDB Molecule:probable serine protease htra3; PDBTitle: crystal structure of the htra3 pdz domain bound to a phage-derived2 ligand (fgrwv) 13 d1lcya1 99.4 11 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 14 c3i18A_ 99.4 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lmo2051 protein; PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b 15 c2kjpA_ 99.3 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ylbl; PDBTitle: solution structure of protein ylbl (bsu15050) from bacillus2 subtilis, northeast structural genomics consortium target3 sr713a 16 c2joaA_ 99.3 18 PDB header:protein binding Chain: A: PDB Molecule:serine protease htra1; PDBTitle: htra1 bound to an optimized peptide: nmr assignment of pdz2 domain and ligand resonances 17 c3ossC_ 99.3 97 PDB header:protein transport Chain: C: PDB Molecule:type 2 secretion system, gspc; PDBTitle: the crystal structure of enterotoxigenic escherichia coli gspc-gspd2 complex from the type ii secretion system 18 d1ky9a1 99.3 22 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 19 d1fc6a3 99.3 12 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:Tail specific protease PDZ domain 20 d2hgaa1 99.2 10 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:MTH1368 C-terminal domain-like 21 c2z9iB_ not modelled 99.2 11 PDB header:hydrolase Chain: B: PDB Molecule:probable serine protease pepd; PDBTitle: crystal structure of rv0983 from mycobacterium tuberculosis-2 proteolytically active form 22 d1ky9b2 not modelled 99.2 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 23 d1sota1 not modelled 99.2 9 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 24 c3rleA_ not modelled 99.1 10 PDB header:membrane protein Chain: A: PDB Molecule:golgi reassembly-stacking protein 2; PDBTitle: crystal structure of grasp55 grasp domain (residues 7-208) 25 c2zplA_ not modelled 99.1 17 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain a 26 c2r3yC_ not modelled 99.1 15 PDB header:hydrolase/hydrolase activator Chain: C: PDB Molecule:protease degs; PDBTitle: crystal structure of the degs protease in complex with the2 ywf activating peptide 27 c4a8aI_ not modelled 99.1 15 PDB header:hydrolase/hydrolase Chain: I: PDB Molecule:periplasmic ph-dependent serine endoprotease degq; PDBTitle: asymmetric cryo-em reconstruction of e. coli degq 12-mer in complex2 with lysozyme 28 c2zpmA_ not modelled 99.0 19 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain b 29 c2eaqA_ not modelled 98.9 21 PDB header:metal binding protein Chain: A: PDB Molecule:lim domain only protein 7; PDBTitle: crystal structure of pdz domain of kiaa0858 (lim), ms07932 from homo sapiens 30 c2krgA_ not modelled 98.8 16 PDB header:signaling protein Chain: A: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf1; PDBTitle: solution structure of human sodium/ hydrogen exchange2 regulatory factor 1(150-358) 31 d1wfga_ not modelled 98.8 19 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 32 d1m5za_ not modelled 98.8 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 33 d1uf1a_ not modelled 98.8 27 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 34 c2eehA_ not modelled 98.8 20 PDB header:metal binding protein Chain: A: PDB Molecule:pdz domain-containing protein 7; PDBTitle: solution structure of first pdz domain of pdz domain2 containing protein 7 35 c2vwrA_ not modelled 98.8 21 PDB header:protein-binding Chain: A: PDB Molecule:ligand of numb protein x 2; PDBTitle: crystal structure of the second pdz domain of numb-binding2 protein 2 36 d1wifa_ not modelled 98.8 13 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 37 c3shuB_ not modelled 98.8 22 PDB header:cell adhesion Chain: B: PDB Molecule:tight junction protein zo-1; PDBTitle: crystal structure of zo-1 pdz3 38 c3l4fD_ not modelled 98.7 17 PDB header:signaling protein/protein binding Chain: D: PDB Molecule:sh3 and multiple ankyrin repeat domains protein PDBTitle: crystal structure of betapix coiled-coil domain and shank2 pdz complex 39 c2kjdA_ not modelled 98.7 14 PDB header:signaling protein Chain: A: PDB Molecule:sodium/hydrogen exchange regulatory cofactor nhe- PDBTitle: solution structure of extended pdz2 domain from nherf1 (150-2 270) 40 c3diwB_ not modelled 98.7 17 PDB header:signaling protein/cell adhesion Chain: B: PDB Molecule:tax1-binding protein 3; PDBTitle: c-terminal beta-catenin bound tip-1 structure 41 c3shwA_ not modelled 98.7 22 PDB header:cell adhesion Chain: A: PDB Molecule:tight junction protein zo-1; PDBTitle: crystal structure of zo-1 pdz3-sh3-guk supramodule complex with2 connexin-45 peptide 42 c2egkC_ not modelled 98.7 13 PDB header:protein binding Chain: C: PDB Molecule:general receptor for phosphoinositides 1- PDBTitle: crystal structure of tamalin pdz-intrinsic ligand fusion2 protein 43 c2komA_ not modelled 98.7 23 PDB header:signaling protein Chain: A: PDB Molecule:partitioning defective 3 homolog; PDBTitle: solution structure of humar par-3b pdz2 (residues 451-549) 44 d1ueqa_ not modelled 98.7 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 45 d1x5qa1 not modelled 98.7 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 46 c2qt5A_ not modelled 98.7 12 PDB header:peptide binding protein Chain: A: PDB Molecule:glutamate receptor-interacting protein 1; PDBTitle: crystal structure of grip1 pdz12 in complex with the fras12 peptide 47 d1q3oa_ not modelled 98.7 18 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 48 d1rgwa_ not modelled 98.7 13 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 49 d1p1da2 not modelled 98.7 14 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 50 d2cssa1 not modelled 98.7 19 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 51 c2q3gA_ not modelled 98.7 11 PDB header:structural genomics Chain: A: PDB Molecule:pdz and lim domain protein 7; PDBTitle: structure of the pdz domain of human pdlim7 bound to a c-2 terminal extension from human beta-tropomyosin 52 d1qaua_ not modelled 98.6 14 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 53 d1t2ma1 not modelled 98.6 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 54 c3khfA_ not modelled 98.6 18 PDB header:transferase Chain: A: PDB Molecule:microtubule-associated serine/threonine-protein PDBTitle: the crystal structure of the pdz domain of human microtubule2 associated serine/threonine kinase 3 (mast3) 55 d2f5ya1 not modelled 98.6 14 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 56 d1wf7a_ not modelled 98.6 12 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 57 d2fe5a1 not modelled 98.6 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 58 c2he4A_ not modelled 98.6 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:na(+)/h(+) exchange regulatory cofactor nhe-rf2; PDBTitle: the crystal structure of the second pdz domain of human2 nherf-2 (slc9a3r2) interacting with a mode 1 pdz binding3 motif 59 d1g9oa_ not modelled 98.6 14 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 60 d1w9ea1 not modelled 98.6 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 61 c2v1wB_ not modelled 98.6 18 PDB header:structural protein Chain: B: PDB Molecule:pdz and lim domain protein 4; PDBTitle: crystal structure of human lim protein ril (pdlim4) pdz2 domain bound to the c-terminal peptide of human alpha-3 actinin-1 62 d1ozia_ not modelled 98.6 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 63 d1p1da1 not modelled 98.6 14 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 64 c1p1dA_ not modelled 98.6 14 PDB header:protein binding Chain: A: PDB Molecule:glutamate receptor interacting protein; PDBTitle: structural insights into the inter-domain chaperoning of2 tandem pdz domains in glutamate receptor interacting3 proteins 65 d1ry4a_ not modelled 98.6 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 66 c2d90A_ not modelled 98.6 22 PDB header:protein binding Chain: A: PDB Molecule:pdz domain containing protein 1; PDBTitle: solution structure of the third pdz domain of pdz domain2 containing protein 1 67 c3qglD_ not modelled 98.6 20 PDB header:protein binding Chain: D: PDB Molecule:sorting nexin-27; PDBTitle: crystal structure of pdz domain of sorting nexin 27 (snx27) in complex2 with the eseskv peptide corresponding to the c-terminal tail of girk3 68 c2gzvA_ not modelled 98.6 9 PDB header:signaling protein Chain: A: PDB Molecule:prkca-binding protein; PDBTitle: the cystal structure of the pdz domain of human pick1 (casp target) 69 c2omjA_ not modelled 98.6 17 PDB header:cell adhesion Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12; PDBTitle: solution structure of larg pdz domain 70 c1u38A_ not modelled 98.6 12 PDB header:protein transport Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding, PDBTitle: auto-inhibition mechanism of x11s/mints family scaffold2 proteins revealed by the closed conformation of the tandem3 pdz domains 71 d1b8qa_ not modelled 98.6 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 72 c3eggC_ not modelled 98.6 11 PDB header:hydrolase Chain: C: PDB Molecule:spinophilin; PDBTitle: crystal structure of a complex between protein phosphatase 1 alpha2 (pp1) and the pp1 binding and pdz domains of spinophilin 73 c3k1rA_ not modelled 98.6 13 PDB header:structural protein Chain: A: PDB Molecule:harmonin; PDBTitle: structure of harmonin npdz1 in complex with the sam-pbm of2 sans 74 d1pdra_ not modelled 98.6 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 75 d1be9a_ not modelled 98.6 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 76 c2v90E_ not modelled 98.6 15 PDB header:protein-binding Chain: E: PDB Molecule:pdz domain-containing protein 3; PDBTitle: crystal structure of the 3rd pdz domain of intestine- and2 kidney-enriched pdz domain ikepp (pdzd3) 77 c2jxoA_ not modelled 98.6 16 PDB header:protein binding Chain: A: PDB Molecule:ezrin-radixin-moesin-binding phosphoprotein 50; PDBTitle: structure of the second pdz domain of nherf-1 78 d1ihja_ not modelled 98.6 27 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 79 c2iwnA_ not modelled 98.6 21 PDB header:signaling protein Chain: A: PDB Molecule:multiple pdz domain protein; PDBTitle: 3rd pdz domain of multiple pdz domain protein mpdz (casp2 target) 80 c2vsvB_ not modelled 98.6 16 PDB header:protein-binding Chain: B: PDB Molecule:rhophilin-2; PDBTitle: crystal structure of the pdz domain of human rhophilin-2 81 d1d5ga_ not modelled 98.6 14 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 82 c1u37A_ not modelled 98.6 12 PDB header:protein transport Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding, PDBTitle: auto-inhibition mechanism of x11s/mints family scaffold2 proteins revealed by the closed conformation of the tandem3 pdz domains 83 c2i04B_ not modelled 98.6 16 PDB header:peptide binding protein Chain: B: PDB Molecule:membrane-associated guanylate kinase, ww and pdz PDBTitle: x-ray crystal structure of magi-1 pdz1 bound to the c-2 terminal peptide of hpv18 e6 84 c2ogpA_ not modelled 98.5 23 PDB header:signaling protein Chain: A: PDB Molecule:partitioning-defective 3 homolog; PDBTitle: solution structure of the second pdz domain of par-3 85 c2o2tB_ not modelled 98.5 26 PDB header:structural protein Chain: B: PDB Molecule:multiple pdz domain protein; PDBTitle: the crystal structure of the 1st pdz domain of mpdz 86 d2byga1 not modelled 98.5 14 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 87 c2ka9A_ not modelled 98.5 16 PDB header:cell adhesion Chain: A: PDB Molecule:disks large homolog 4; PDBTitle: solution structure of psd-95 pdz12 complexed with cypin2 peptide 88 d1q7xa_ not modelled 98.5 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 89 c2q9vA_ not modelled 98.5 16 PDB header:transferase Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz domain- PDBTitle: crystal structure of the c890s mutant of the 4th pdz domain of human2 membrane associated guanylate kinase 90 d1uepa_ not modelled 98.5 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 91 c2z17A_ not modelled 98.5 15 PDB header:protein binding Chain: A: PDB Molecule:pleckstrin homology sec7 and coiled-coil domains- PDBTitle: crystal sturcture of pdz domain from human pleckstrin2 homology, sec7 92 d1wh1a_ not modelled 98.5 21 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 93 c2iwoA_ not modelled 98.5 14 PDB header:signaling protein Chain: A: PDB Molecule:multiple pdz domain protein; PDBTitle: 12th pdz domain of multiple pdz domain protein mpdz (casp2 target) 94 c2qg1A_ not modelled 98.5 27 PDB header:signaling protein Chain: A: PDB Molecule:multiple pdz domain protein; PDBTitle: crystal structure of the 11th pdz domain of mpdz (mupp1) 95 d1uhpa_ not modelled 98.5 20 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 96 c2k1zA_ not modelled 98.5 23 PDB header:signaling protein Chain: A: PDB Molecule:partitioning-defective 3 homolog; PDBTitle: solution structure of par-3 pdz3 97 d1um1a_ not modelled 98.5 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 98 c2dm8A_ not modelled 98.5 16 PDB header:protein binding Chain: A: PDB Molecule:inad-like protein; PDBTitle: solution structure of the eighth pdz domain of human inad-2 like protein 99 d1wf8a1 not modelled 98.5 11 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 100 c3bpuA_ not modelled 98.5 25 PDB header:transferase Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz domain- PDBTitle: crystal structure of the 3rd pdz domain of human membrane associated2 guanylate kinase, c677s and c709s double mutant 101 c3cyyA_ not modelled 98.5 22 PDB header:peptide binding protein Chain: A: PDB Molecule:tight junction protein zo-1; PDBTitle: the crystal structure of zo-1 pdz2 in complex with the cx43 peptide 102 c2jilA_ not modelled 98.5 11 PDB header:membrane protein Chain: A: PDB Molecule:glutamate receptor interacting protein-1; PDBTitle: crystal structure of 2nd pdz domain of glutamate receptor2 interacting protein-1 (grip1) 103 d2f0aa1 not modelled 98.5 21 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 104 d1tp5a1 not modelled 98.5 17 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 105 d1ueza_ not modelled 98.5 20 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 106 c2jikB_ not modelled 98.5 21 PDB header:membrane protein Chain: B: PDB Molecule:synaptojanin-2 binding protein; PDBTitle: crystal structure of pdz domain of synaptojanin-2 binding2 protein 107 c2osgB_ not modelled 98.5 26 PDB header:cell adhesion Chain: B: PDB Molecule:tight junction protein zo-2; PDBTitle: solution structure and binding property of the domain-2 swapped dimer of zo2pdz2 108 c3r0hA_ not modelled 98.5 12 PDB header:peptide binding protein Chain: A: PDB Molecule:inactivation-no-after-potential d protein; PDBTitle: structure of inad pdz45 in complex with ng2 peptide 109 d1rzxa_ not modelled 98.5 16 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 110 c3ggeA_ not modelled 98.5 13 PDB header:protein binding Chain: A: PDB Molecule:pdz domain-containing protein gipc2; PDBTitle: crystal structure of the pdz domain of pdz domain-containing protein2 gipc2 111 c2edzA_ not modelled 98.5 19 PDB header:signaling protein Chain: A: PDB Molecule:pdz domain-containing protein 1; PDBTitle: solution structures of the pdz domain of mus musculus pdz2 domain-containing protein 1 112 d1nf3c_ not modelled 98.5 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 113 d1whaa_ not modelled 98.5 22 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 114 c2dkrA_ not modelled 98.5 16 PDB header:protein transport Chain: A: PDB Molecule:lin-7 homolog b; PDBTitle: solution structure of the pdz domain from human lin-72 homolog b 115 c3hpmA_ not modelled 98.5 10 PDB header:protein binding Chain: A: PDB Molecule:protein interacting with prkca 1; PDBTitle: oxidized dimeric pick1 pdz c46g mutant in complex with the carboxyl2 tail peptide of glur2 116 d1kwaa_ not modelled 98.5 13 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 117 c2db5A_ not modelled 98.5 29 PDB header:protein binding Chain: A: PDB Molecule:inad-like protein; PDBTitle: solution structure of the first pdz domain of inad-like2 protein 118 d1x5ra1 not modelled 98.5 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:PDZ domain 119 c2djtA_ not modelled 98.5 14 PDB header:signaling protein Chain: A: PDB Molecule:unnamed protein product; PDBTitle: solution structures of the pdz domain of human unnamed2 protein product 120 c2yuyA_ not modelled 98.5 22 PDB header:signaling protein Chain: A: PDB Molecule:rho gtpase activating protein 21; PDBTitle: solution structure of pdz domain of rho gtpase activating2 protein 21

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0