Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP00816
DateThu Jan 5 10:56:55 GMT 2012
Unique Job IDec5ed00a7f6c55f3

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2iv1J_
Top template information
PDB header:lyase
Chain: J: PDB Molecule:cyanate hydratase;
PDBTitle: site directed mutagenesis of key residues involved in the2 catalytic mechanism of cyanase
Confidence and coverage
Confidence:100.0% Coverage:100%
156 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARL
Secondary structure 













SS confidence 



























































Disorder  ??





















?


































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   .........70.........80.........90.........100.........110.........120
Sequence  VGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGI
Secondary structure 






















SS confidence 



























































Disorder 

















?

????????






























Disorder confidence 



























































 
   .........130.........140.........150......
Sequence  ISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
Secondary structure 















SS confidence 



































Disorder 










???????












?????
Disorder confidence 



































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2iv1 chain J

3D model

Region: 1 - 156
Aligned: 156
Modelled: 156
Confidence: 100.0%
Identity: 99%
PDB header:lyase
Chain: J: PDB Molecule:cyanate hydratase;
PDBTitle: site directed mutagenesis of key residues involved in the2 catalytic mechanism of cyanase

Phyre2

PDB 1dwk chain A domain 2

3D model

Region: 87 - 156
Aligned: 70
Modelled: 70
Confidence: 100.0%
Identity: 97%
Fold: Cyanase C-terminal domain
Superfamily: Cyanase C-terminal domain
Family: Cyanase C-terminal domain

Phyre2

PDB 1dwk chain A domain 1

3D model

Region: 1 - 86
Aligned: 86
Modelled: 85
Confidence: 100.0%
Identity: 98%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: Cyanase N-terminal domain

Phyre2

PDB 1y9q chain A

3D model

Region: 9 - 72
Aligned: 64
Modelled: 63
Confidence: 97.1%
Identity: 14%
PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, hth_3 family;
PDBTitle: crystal structure of hth_3 family transcriptional regulator2 from vibrio cholerae

Phyre2

PDB 1y7y chain A domain 1

3D model

Region: 5 - 72
Aligned: 66
Modelled: 68
Confidence: 97.1%
Identity: 17%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: SinR domain-like

Phyre2

PDB 1adr chain A

3D model

Region: 6 - 72
Aligned: 64
Modelled: 67
Confidence: 97.0%
Identity: 13%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: Phage repressors

Phyre2

PDB 3clc chain C

3D model

Region: 11 - 72
Aligned: 62
Modelled: 62
Confidence: 97.0%
Identity: 11%
PDB header:transcription regulator/dna
Chain: C: PDB Molecule:regulatory protein;
PDBTitle: crystal structure of the restriction-modification controller protein2 c.esp1396i tetramer in complex with its natural 35 base-pair operator

Phyre2

PDB 3f6w chain E

3D model

Region: 4 - 72
Aligned: 69
Modelled: 69
Confidence: 97.0%
Identity: 16%
PDB header:dna binding protein
Chain: E: PDB Molecule:xre-family like protein;
PDBTitle: xre-family like protein from pseudomonas syringae pv. tomato str.2 dc3000

Phyre2

PDB 2b5a chain A domain 1

3D model

Region: 11 - 72
Aligned: 62
Modelled: 62
Confidence: 97.0%
Identity: 18%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: SinR domain-like

Phyre2

PDB 2bno chain A

3D model

Region: 12 - 68
Aligned: 57
Modelled: 57
Confidence: 97.0%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:epoxidase;
PDBTitle: the structure of hydroxypropylphosphonic acid epoxidase2 from s. wedmorenis.

Phyre2

PDB 2ewt chain A

3D model

Region: 6 - 72
Aligned: 67
Modelled: 67
Confidence: 96.9%
Identity: 10%
PDB header:dna binding protein
Chain: A: PDB Molecule:putative dna-binding protein;
PDBTitle: crystal structure of the dna-binding domain of bldd

Phyre2

PDB 3ivp chain D

3D model

Region: 8 - 72
Aligned: 65
Modelled: 65
Confidence: 96.9%
Identity: 14%
PDB header:dna binding protein
Chain: D: PDB Molecule:putative transposon-related dna-binding protein;
PDBTitle: the structure of a possible transposon-related dna-binding protein2 from clostridium difficile 630.

Phyre2

PDB 3f52 chain A

3D model

Region: 9 - 72
Aligned: 64
Modelled: 64
Confidence: 96.8%
Identity: 16%
PDB header:transcription activator
Chain: A: PDB Molecule:clp gene regulator (clgr);
PDBTitle: crystal structure of the clp gene regulator clgr from c. glutamicum

Phyre2

PDB 2o38 chain A domain 1

3D model

Region: 10 - 68
Aligned: 59
Modelled: 59
Confidence: 96.8%
Identity: 24%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: NE1354

Phyre2

PDB 2o38 chain A

3D model

Region: 10 - 68
Aligned: 59
Modelled: 59
Confidence: 96.8%
Identity: 24%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: putative xre family transcriptional regulator

Phyre2

PDB 3cec chain A

3D model

Region: 16 - 76
Aligned: 61
Modelled: 61
Confidence: 96.7%
Identity: 23%
PDB header:transcription
Chain: A: PDB Molecule:putative antidote protein of plasmid maintenance system;
PDBTitle: crystal structure of a putative antidote protein of plasmid2 maintenance system (npun_f2943) from nostoc punctiforme pcc 73102 at3 1.60 a resolution

Phyre2

PDB 3op9 chain A

3D model

Region: 14 - 72
Aligned: 59
Modelled: 59
Confidence: 96.7%
Identity: 15%
PDB header:transcription regulator
Chain: A: PDB Molecule:pli0006 protein;
PDBTitle: crystal structure of transcriptional regulator from listeria innocua

Phyre2

PDB 1y9q chain A domain 1

3D model

Region: 9 - 72
Aligned: 64
Modelled: 63
Confidence: 96.7%
Identity: 14%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: Probable transcriptional regulator VC1968, N-terminal domain

Phyre2

PDB 3kxa chain D

3D model

Region: 18 - 74
Aligned: 57
Modelled: 57
Confidence: 96.7%
Identity: 16%
PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of ngo0477 from neisseria gonorrhoeae

Phyre2

PDB 1rio chain A

3D model

Region: 4 - 72
Aligned: 69
Modelled: 69
Confidence: 96.7%
Identity: 25%
Fold: lambda repressor-like DNA-binding domains
Superfamily: lambda repressor-like DNA-binding domains
Family: Phage repressors

Phyre2
1

c2iv1J_
2

d1dwka2
3

d1dwka1
4

c1y9qA_
5

d1y7ya1
6

d1adra_
7

c3clcC_
8

c3f6wE_
9

d2b5aa1
10

c2bnoA_
11

c2ewtA_
12

c3ivpD_
13

c3f52A_
14

d2o38a1
15

c2o38A_
16

c3cecA_
17

c3op9A_
18

d1y9qa1
19

c3kxaD_
20

d1rioa_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2iv1J_



100.0 99 PDB header:lyase
Chain: J: PDB Molecule:cyanate hydratase;
PDBTitle: site directed mutagenesis of key residues involved in the2 catalytic mechanism of cyanase
2d1dwka2



100.0 97 Fold:Cyanase C-terminal domain
Superfamily:Cyanase C-terminal domain
Family:Cyanase C-terminal domain
3d1dwka1



100.0 98 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Cyanase N-terminal domain
4c1y9qA_



97.1 14 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, hth_3 family;
PDBTitle: crystal structure of hth_3 family transcriptional regulator2 from vibrio cholerae
5d1y7ya1



97.1 17 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
6d1adra_



97.0 13 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
7c3clcC_



97.0 11 PDB header:transcription regulator/dna
Chain: C: PDB Molecule:regulatory protein;
PDBTitle: crystal structure of the restriction-modification controller protein2 c.esp1396i tetramer in complex with its natural 35 base-pair operator
8c3f6wE_



97.0 16 PDB header:dna binding protein
Chain: E: PDB Molecule:xre-family like protein;
PDBTitle: xre-family like protein from pseudomonas syringae pv. tomato str.2 dc3000
9d2b5aa1



97.0 18 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
10c2bnoA_



97.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:epoxidase;
PDBTitle: the structure of hydroxypropylphosphonic acid epoxidase2 from s. wedmorenis.
11c2ewtA_



96.9 10 PDB header:dna binding protein
Chain: A: PDB Molecule:putative dna-binding protein;
PDBTitle: crystal structure of the dna-binding domain of bldd
12c3ivpD_



96.9 14 PDB header:dna binding protein
Chain: D: PDB Molecule:putative transposon-related dna-binding protein;
PDBTitle: the structure of a possible transposon-related dna-binding protein2 from clostridium difficile 630.
13c3f52A_



96.8 16 PDB header:transcription activator
Chain: A: PDB Molecule:clp gene regulator (clgr);
PDBTitle: crystal structure of the clp gene regulator clgr from c. glutamicum
14d2o38a1



96.8 24 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:NE1354
15c2o38A_



96.8 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: putative xre family transcriptional regulator
16c3cecA_



96.7 23 PDB header:transcription
Chain: A: PDB Molecule:putative antidote protein of plasmid maintenance system;
PDBTitle: crystal structure of a putative antidote protein of plasmid2 maintenance system (npun_f2943) from nostoc punctiforme pcc 73102 at3 1.60 a resolution
17c3op9A_



96.7 15 PDB header:transcription regulator
Chain: A: PDB Molecule:pli0006 protein;
PDBTitle: crystal structure of transcriptional regulator from listeria innocua
18d1y9qa1



96.7 14 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Probable transcriptional regulator VC1968, N-terminal domain
19c3kxaD_



96.7 16 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of ngo0477 from neisseria gonorrhoeae
20d1rioa_



96.7 25 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
21c3eusB_



not modelled 96.6 12 PDB header:dna binding protein
Chain: B: PDB Molecule:dna-binding protein;
PDBTitle: the crystal structure of the dna binding protein from silicibacter2 pomeroyi
22d1llib_



not modelled 96.6 24 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
23d2icta1



not modelled 96.6 25 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
24d2r1jl1



not modelled 96.6 10 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
25c2kpjA_



not modelled 96.6 9 PDB header:transcription regulator
Chain: A: PDB Molecule:sos-response transcriptional repressor, lexa;
PDBTitle: solution structure of protein sos-response transcriptional2 repressor, lexa from eubacterium rectale. northeast3 structural genomics consortium target err9a
26c3dnvB_



not modelled 96.5 17 PDB header:transcription/dna
Chain: B: PDB Molecule:hth-type transcriptional regulator hipb;
PDBTitle: mdt protein
27d2ofya1



not modelled 96.5 19 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
28c3bdnB_



not modelled 96.4 27 PDB header:transcription/dna
Chain: B: PDB Molecule:lambda repressor;
PDBTitle: crystal structure of the lambda repressor
29c1b0nA_



not modelled 96.4 20 PDB header:transcription regulator
Chain: A: PDB Molecule:protein (sinr protein);
PDBTitle: sinr protein/sini protein complex
30c3b7hA_



not modelled 96.4 15 PDB header:structural protein
Chain: A: PDB Molecule:prophage lp1 protein 11;
PDBTitle: crystal structure of the prophage lp1 protein 11
31d1x57a1



not modelled 96.3 11 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:EDF1-like
32d1lmb3_



not modelled 96.3 25 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
33d1b0na2



not modelled 96.3 20 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
34c3pxpA_



not modelled 96.3 13 PDB header:transcription regulator
Chain: A: PDB Molecule:helix-turn-helix domain protein;
PDBTitle: crystal structure of a pas and dna binding domain containing protein2 (caur_2278) from chloroflexus aurantiacus j-10-fl at 2.30 a3 resolution
35c3mlfC_



not modelled 96.3 7 PDB header:transcription regulator
Chain: C: PDB Molecule:transcriptional regulator;
PDBTitle: putative transcriptional regulator from staphylococcus aureus.
36c2wusR_



not modelled 96.3 13 PDB header:structural protein
Chain: R: PDB Molecule:putative uncharacterized protein;
PDBTitle: bacterial actin mreb assembles in complex with cell shape2 protein rodz
37c3trbA_



not modelled 96.3 21 PDB header:dna binding protein
Chain: A: PDB Molecule:virulence-associated protein i;
PDBTitle: structure of an addiction module antidote protein of a higa (higa)2 family from coxiella burnetii
38c3t76A_



not modelled 96.2 11 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator vanug;
PDBTitle: crystal structure of transcriptional regulator vanug, form ii
39d2a6ca1



not modelled 96.2 14 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:NE1354
40c2ebyA_



not modelled 96.1 25 PDB header:transcription
Chain: A: PDB Molecule:putative hth-type transcriptional regulator ybaq;
PDBTitle: crystal structure of a hypothetical protein from e. coli
41d1utxa_



not modelled 96.1 16 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
42d1sq8a_



not modelled 96.1 16 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
43d2croa_



not modelled 96.1 12 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
44d1r69a_



not modelled 96.0 14 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
45c3fymA_



not modelled 95.9 10 PDB header:dna binding protein
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: the 1a structure of ymfm, a putative dna-binding membrane2 protein from staphylococcus aureus
46c3omtA_



not modelled 95.8 9 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: putative antitoxin component, chu_2935 protein, from xre family from2 prevotella buccae.
47c3bs3A_



not modelled 95.8 18 PDB header:dna binding protein
Chain: A: PDB Molecule:putative dna-binding protein;
PDBTitle: crystal structure of a putative dna-binding protein from bacteroides2 fragilis
48c3lisB_



not modelled 95.6 16 PDB header:transcription
Chain: B: PDB Molecule:csp231i c protein;
PDBTitle: crystal structure of the restriction-modification controller protein2 c.csp231i (monoclinic form)
49c2xcjB_



not modelled 95.1 20 PDB header:viral protein
Chain: B: PDB Molecule:c protein;
PDBTitle: crystal structure of p2 c, the immunity repressor of2 temperate e. coli phage p2
50c2jvlA_



not modelled 94.4 18 PDB header:transcription
Chain: A: PDB Molecule:trmbf1;
PDBTitle: nmr structure of the c-terminal domain of mbf1 of trichoderma reesei
51c2ef8A_



not modelled 94.1 21 PDB header:transcription regulator
Chain: A: PDB Molecule:putative transcription factor;
PDBTitle: crystal structure of c.ecot38is
52d1nera_



not modelled 92.7 17 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:Phage repressors
53c3fmyA_



not modelled 90.4 17 PDB header:dna binding protein
Chain: A: PDB Molecule:hth-type transcriptional regulator mqsa
PDBTitle: structure of the c-terminal domain of the e. coli protein2 mqsa (ygit/b3021)
54c2fjrB_



not modelled 87.9 12 PDB header:transcription regulator
Chain: B: PDB Molecule:repressor protein ci;
PDBTitle: crystal structure of bacteriophage 186
55c2ppxA_



not modelled 85.0 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein atu1735;
PDBTitle: crystal structure of a hth xre-family like protein from agrobacterium2 tumefaciens
56d2ppxa1



not modelled 85.0 12 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:SinR domain-like
57d1efaa1



not modelled 78.2 18 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
58d1lcda_



not modelled 77.7 18 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
59d2bjca1



not modelled 76.6 20 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
60c1zx4B_



not modelled 74.8 25 PDB header:translation
Chain: B: PDB Molecule:plasmid partition par b protein;
PDBTitle: structure of parb bound to dna
61c3gn5B_



not modelled 72.6 15 PDB header:dna binding protein
Chain: B: PDB Molecule:hth-type transcriptional regulator mqsa (ygit/b3021);
PDBTitle: structure of the e. coli protein mqsa (ygit/b3021)
62c2qfcB_



not modelled 71.3 15 PDB header:transcription regulation
Chain: B: PDB Molecule:plcr protein;
PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr
63d2hsga1



not modelled 71.2 13 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
64d1ggaa2



not modelled 69.6 22 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:GAPDH-like
65c2l8nA_



not modelled 67.4 16 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional repressor cytr;
PDBTitle: nmr structure of the cytidine repressor dna binding domain in presence2 of operator half-site dna
66d1vz0a1



not modelled 67.2 28 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:KorB DNA-binding domain-like
Family:KorB DNA-binding domain-like
67d1qpza1



not modelled 67.1 11 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
68c2lcvA_



not modelled 66.5 16 PDB header:transcription regulator
Chain: A: PDB Molecule:hth-type transcriptional repressor cytr;
PDBTitle: structure of the cytidine repressor dna-binding domain; an alternate2 calculation
69c3pv9D_



not modelled 64.8 16 PDB header:immune system
Chain: D: PDB Molecule:putative uncharacterized protein ph1245;
PDBTitle: structure of ph1245, a cas1 from pyrococcus horikoshii
70d1or7a1



not modelled 64.2 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
71d1v6ga2



not modelled 61.8 43 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
72d1uxca_



not modelled 60.0 18 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
73c1or7A_



not modelled 59.9 18 PDB header:transcription
Chain: A: PDB Molecule:rna polymerase sigma-e factor;
PDBTitle: crystal structure of escherichia coli sigmae with the cytoplasmic2 domain of its anti-sigma rsea
74d1ku7a_



not modelled 53.8 8 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
75c3rmiA_



not modelled 53.5 21 PDB header:isomerase
Chain: A: PDB Molecule:chorismate mutase protein;
PDBTitle: crystal structure of chorismate mutase from bartonella henselae str.2 houston-1 in complex with malate
76c3h5tA_



not modelled 51.4 20 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, laci family;
PDBTitle: crystal structure of a transcriptional regulator, lacl2 family protein from corynebacterium glutamicum
77c2axzC_



not modelled 50.9 4 PDB header:transcription
Chain: C: PDB Molecule:prgx;
PDBTitle: crystal structure of prgx/ccf10 complex
78c3mkyP_



not modelled 50.6 18 PDB header:dna binding protein/dna
Chain: P: PDB Molecule:protein sopb;
PDBTitle: structure of sopb(155-323)-18mer dna complex, i23 form
79d2gtvx1



not modelled 50.4 11 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:monomeric chorismate mutase
80d1ttya_



not modelled 50.1 8 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
81c3r1fO_



not modelled 49.5 9 PDB header:transcription
Chain: O: PDB Molecule:esx-1 secretion-associated regulator espr;
PDBTitle: crystal structure of a key regulator of virulence in mycobacterium2 tuberculosis
82d2p7vb1



not modelled 49.0 8 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
83c2o8xA_



not modelled 48.7 21 PDB header:transcription
Chain: A: PDB Molecule:probable rna polymerase sigma-c factor;
PDBTitle: crystal structure of the "-35 element" promoter recognition domain of2 mycobacterium tuberculosis sigc
84d1uxda_



not modelled 48.4 18 Fold:lambda repressor-like DNA-binding domains
Superfamily:lambda repressor-like DNA-binding domains
Family:GalR/LacI-like bacterial regulator
85c3t72o_



not modelled 48.0 9 PDB header:transcription/dna
Chain: O: PDB Molecule:pho box dna (strand 1);
PDBTitle: phob(e)-sigma70(4)-(rnap-betha-flap-tip-helix)-dna transcription2 activation sub-complex
86d1ku3a_



not modelled 47.6 9 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
87d1r71a_



not modelled 47.1 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:KorB DNA-binding domain-like
Family:KorB DNA-binding domain-like
88d1rp3a2



not modelled 47.0 9 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:Sigma4 domain
89d1k3ta2



not modelled 46.8 24 Fold:FwdE/GAPDH domain-like
Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Family:GAPDH-like
90c3bd1B_



not modelled 46.4 9 PDB header:transcription
Chain: B: PDB Molecule:cro protein;
PDBTitle: structure of the cro protein from putative prophage element xfaso 1 in2 xylella fastidiosa strain ann-1
91d2cg4a1



not modelled 44.3 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
92d1i1ga1



not modelled 44.1 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:Lrp/AsnC-like transcriptional regulator N-terminal domain
93c2kiqA_



not modelled 44.0 17 PDB header:transcription regulator
Chain: A: PDB Molecule:transcription elongation regulator 1;
PDBTitle: solution structure of the ff domain 2 of human transcription2 elongation factor ca150
94d1gv2a2



not modelled 43.1 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Myb/SANT domain
95c2llkA_



not modelled 42.4 16 PDB header:cell cycle, transcription
Chain: A: PDB Molecule:cyclin-d-binding myb-like transcription factor 1;
PDBTitle: solution nmr structure of the n-terminal myb-like 1 domain of the2 human cyclin-d-binding transcription factor 1 (hdmp1), northeast3 structural genomics consortium (nesg) target id hr8011a
96d2csba5



not modelled 41.2 31 Fold:Topoisomerase V catalytic domain-like
Superfamily:Topoisomerase V catalytic domain-like
Family:Topoisomerase V catalytic domain-like
97c2gbbA_



not modelled 41.1 22 PDB header:isomerase
Chain: A: PDB Molecule:putative chorismate mutase;
PDBTitle: crystal structure of secreted chorismate mutase from2 yersinia pestis
98c3kjxD_



not modelled 39.5 20 PDB header:transcription regulator
Chain: D: PDB Molecule:transcriptional regulator, laci family;
PDBTitle: crystal structure of a transcriptional regulator, lacl2 family protein from silicibacter pomeroyi
99d2fp1a1



not modelled 39.1 26 Fold:Chorismate mutase II
Superfamily:Chorismate mutase II
Family:Secreted chorismate mutase-like
100c1zgwA_



not modelled 37.7 10 PDB header:transcription regulator/dna
Chain: A: PDB Molecule:ada polyprotein;
PDBTitle: nmr structure of e. coli ada protein in complex with dna
101c1rp3G_



not modelled 36.9 11 PDB header:transcription
Chain: G: PDB Molecule:rna polymerase sigma factor sigma-28 (flia);
PDBTitle: cocrystal structure of the flagellar sigma/anti-sigma2 complex, sigma-28/flgm
102d1tc3c_



not modelled 36.1 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Recombinase DNA-binding domain
103c1u78A_



not modelled 36.0 17 PDB header:dna binding protein/dna
Chain: A: PDB Molecule:transposable element tc3 transposase;
PDBTitle: structure of the bipartite dna-binding domain of tc32 transposase bound to transposon dna
104d1k78a1



not modelled 35.8 12 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Paired domain
105d2vkea1



not modelled 35.4 24 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:Tetracyclin repressor-like, N-terminal domain
106c1r71B_



not modelled 35.1 21 PDB header:transcription/dna
Chain: B: PDB Molecule:transcriptional repressor protein korb;
PDBTitle: crystal structure of the dna binding domain of korb in2 complex with the operator dna
107c3lfxE_



not modelled 34.9 20 PDB header:structural genomics, unknown function
Chain: E: PDB Molecule:uncharacterized protein;
PDBTitle: structure of tm1797, a cas1 protein from thermotoga maritima
108c2cfxD_



not modelled 34.7 24 PDB header:transcription
Chain: D: PDB Molecule:hth-type transcriptional regulator lrpc;
PDBTitle: structure of b.subtilis lrpc
109d2j0pa1



not modelled 33.9 21 Fold:Heme iron utilization protein-like
Superfamily:Heme iron utilization protein-like
Family:HemS/ChuS-like
110d1xsva_



not modelled 33.3 24 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:YlxM/p13-like
111c2e71A_



not modelled 32.8 16 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation regulator 1;
PDBTitle: solution structure of the second ff domain of human2 transcription factor ca150
112c3hugA_



not modelled 32.5 24 PDB header:transcription/membrane protein
Chain: A: PDB Molecule:rna polymerase sigma factor;
PDBTitle: crystal structure of mycobacterium tuberculosis anti-sigma factor rsla2 in complex with -35 promoter binding domain of sigl
113d1s7oa_



not modelled 31.9 27 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Sigma3 and sigma4 domains of RNA polymerase sigma factors
Family:YlxM/p13-like
114c3m6zA_



not modelled 31.7 31 PDB header:isomerase
Chain: A: PDB Molecule:topoisomerase v;
PDBTitle: crystal structure of an n-terminal 44 kda fragment of topoisomerase v2 in the presence of guanidium hydrochloride
115c3i4pA_



not modelled 31.6 24 PDB header:transcription regulator
Chain: A: PDB Molecule:transcriptional regulator, asnc family;
PDBTitle: crystal structure of asnc family transcriptional regulator from2 agrobacterium tumefaciens
116d1d5ya1



not modelled 31.6 12 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:AraC type transcriptional activator
117c3mzyA_



not modelled 30.8 15 PDB header:rna binding protein
Chain: A: PDB Molecule:rna polymerase sigma-h factor;
PDBTitle: the crystal structure of the rna polymerase sigma-h factor from2 fusobacterium nucleatum to 2.5a
118c3osgA_



not modelled 29.5 13 PDB header:transcription/dna
Chain: A: PDB Molecule:myb21;
PDBTitle: the structure of protozoan parasite trichomonas vaginalis myb2 in2 complex with mre-1-12 dna
119c2v9vA_



not modelled 29.3 17 PDB header:transcription
Chain: A: PDB Molecule:selenocysteine-specific elongation factor;
PDBTitle: crystal structure of moorella thermoacetica selb(377-511)
120c2vprA_



not modelled 29.3 16 PDB header:transcription
Chain: A: PDB Molecule:tetracycline resistance repressor protein;
PDBTitle: tet repressor class h in complex with 5a,6-2 anhydrotetracycline-mg

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0