Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	S	R	L	P	I	A	I	Q	Q	A	V	M	R	R	L	R	E	K	L	A	Q	A	N	L	K	L	G	R	N	Y	P	E	P	K	L	S	Y	T	Q	R	G	T	S	A	G	T	A	W	L	E	S	Y	E	I	R	L	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	V	L	L	L	E	N	S	E	A	F	I	E	E	V	V	P	H	E	L	A	H	L	L	V	W	K	H	F	G	R	V	A	P	H	G	K	E	W	K	W	M	M	E	N	V	L	G	V	P	A	R	R	T	H	Q	F	E	L	Q
Secondary structure
SS confidence
Disorder																																?	?	?	?																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
Sequence		S	V	R	R	N	T	F	P	Y	R	C	K	C	Q	E	H	Q	L	T	V	R	R	H	N	R	V	V	R	G	E	A	V	Y	R	C	V	H	C	G	E	Q	L	V	A	K
Secondary structure
SS confidence
Disorder		?	?	?																										?	?										?	?		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3cqb chain B Region: 15 - 84 Aligned: 68 Modelled: 70 Confidence: 96.9% Identity: 18% PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 Phyre2 PDB 2xdt chain A Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 96.1% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1 Phyre2 PDB 3mdj chain B Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 96.0% Identity: 26% PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor,2 bestatin Phyre2 PDB 3qnf chain A Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 96.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1 Phyre2 PDB 3b37 chain A Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 95.5% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of e. coli aminopeptidase n in complex with tyrosine Phyre2 PDB 3se6 chain A Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 95.5% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2; PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2 Phyre2 PDB 2gtq chain A Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 95.4% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis Phyre2 PDB 3ebh chain A Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 95.4% Identity: 25% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:m1 family aminopeptidase; PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin Phyre2 PDB 1z5h chain B Region: 12 - 84 Aligned: 73 Modelled: 73 Confidence: 95.1% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum Phyre2 PDB 3dtk chain A Region: 7 - 86 Aligned: 75 Modelled: 80 Confidence: 94.7% Identity: 24% PDB header:gene regulation Chain: A: PDB Molecule:irre protein; PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae Phyre2 PDB 3c37 chain B Region: 13 - 84 Aligned: 71 Modelled: 72 Confidence: 94.5% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m48 family; PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a Phyre2 PDB 3cia chain A Region: 8 - 84 Aligned: 74 Modelled: 74 Confidence: 93.6% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea Phyre2 PDB 2xpy chain A Region: 9 - 84 Aligned: 73 Modelled: 76 Confidence: 92.2% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae Phyre2 PDB 1lml chain A Region: 51 - 84 Aligned: 34 Modelled: 34 Confidence: 91.5% Identity: 24% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Leishmanolysin Phyre2 PDB 3b7u chain X Region: 8 - 84 Aligned: 74 Modelled: 77 Confidence: 91.3% Identity: 15% PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan Phyre2 PDB 3b7s chain A domain 3 Region: 12 - 84 Aligned: 70 Modelled: 73 Confidence: 90.2% Identity: 16% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Leukotriene A4 hydrolase catalytic domain Phyre2 PDB 2lcq chain A Region: 117 - 165 Aligned: 43 Modelled: 49 Confidence: 85.2% Identity: 14% PDB header:metal binding protein Chain: A: PDB Molecule:putative toxin vapc6; PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii Phyre2 PDB 1j7n chain A domain 2 Region: 45 - 105 Aligned: 60 Modelled: 61 Confidence: 83.6% Identity: 18% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Anthrax toxin lethal factor, N- and C-terminal domains Phyre2 PDB 1oz9 chain A Region: 19 - 106 Aligned: 85 Modelled: 88 Confidence: 76.6% Identity: 13% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Predicted metal-dependent hydrolase Phyre2 PDB 2ejq chain A domain 1 Region: 69 - 89 Aligned: 21 Modelled: 21 Confidence: 72.9% Identity: 38% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: TTHA0227-like Phyre2 1 c3cqbB_ 2 c2xdtA_ 3 c3mdjB_ 4 c3qnfA_ 5 c3b37A_ 6 c3se6A_ 7 c2gtqA_ 8 c3ebhA_ 9 c1z5hB_ 10 c3dtkA_ 11 c3c37B_ 12 c3ciaA_ 13 c2xpyA_ 14 d1lmla_ 15 c3b7uX_ 16 d3b7sa3 17 c2lcqA_ 18 d1j7na2 19 d1oz9a_ 20 d2ejqa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3cqbB_ 96.9 18 PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 2 c2xdtA_ 96.1 26 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1 3 c3mdjB_ 96.0 26 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor,2 bestatin 4 c3qnfA_ 96.0 19 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1 5 c3b37A_ 95.5 18 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of e. coli aminopeptidase n in complex with tyrosine 6 c3se6A_ 95.5 22 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2; PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2 7 c2gtqA_ 95.4 22 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis 8 c3ebhA_ 95.4 25 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:m1 family aminopeptidase; PDBTitle: structure of the m1 alanylaminopeptidase from malaria complexed with2 bestatin 9 c1z5hB_ 95.1 16 PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum 10 c3dtkA_ 94.7 24 PDB header:gene regulation Chain: A: PDB Molecule:irre protein; PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae 11 c3c37B_ 94.5 14 PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m48 family; PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a 12 c3ciaA_ 93.6 14 PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea 13 c2xpyA_ 92.2 15 PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae 14 d1lmla_ 91.5 24 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leishmanolysin 15 c3b7uX_ 91.3 15 PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan 16 d3b7sa3 90.2 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leukotriene A4 hydrolase catalytic domain 17 c2lcqA_ 85.2 14 PDB header:metal binding protein Chain: A: PDB Molecule:putative toxin vapc6; PDBTitle: solution structure of the endonuclease nob1 from p.horikoshii 18 d1j7na2 83.6 18 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Anthrax toxin lethal factor, N- and C-terminal domains 19 d1oz9a_ 76.6 13 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Predicted metal-dependent hydrolase 20 d2ejqa1 72.9 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 21 d1mmqa_ not modelled 72.1 15 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 22 d1p3ja2 not modelled 71.0 18 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 23 d2ak3a2 not modelled 70.8 15 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 24 d1zina2 not modelled 70.7 24 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 25 d1s3ga2 not modelled 70.0 18 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 26 d1e4va2 not modelled 68.5 15 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 27 c2jsdA_ not modelled 66.2 11 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-20; PDBTitle: solution structure of mmp20 complexed with nngh 28 c2l0rA_ not modelled 66.0 24 PDB header:hydrolase,toxin Chain: A: PDB Molecule:lethal factor; PDBTitle: conformational dynamics of the anthrax lethal factor catalytic center 29 d1vd4a_ not modelled 65.5 18 Fold:Rubredoxin-like Superfamily:Zinc beta-ribbon Family:Transcriptional factor domain 30 c2vqxA_ not modelled 63.3 39 PDB header:hydrolase Chain: A: PDB Molecule:metalloproteinase; PDBTitle: precursor of protealysin, metalloproteinase from serratia2 proteamaculans. 31 d1akya2 not modelled 62.1 15 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 32 d1kjpa_ not modelled 61.5 39 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 33 d1npca_ not modelled 61.1 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 34 d3e11a1 not modelled 61.1 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 35 d1bqba_ not modelled 60.6 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 36 c1slmA_ not modelled 60.2 18 PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme 37 c3nqxA_ not modelled 58.1 28 PDB header:hydrolase Chain: A: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of vibriolysin mcp-02 mature enzyme, a zinc2 metalloprotease from m4 family 38 c1f2iI_ not modelled 57.8 25 PDB header:transcription/dna Chain: I: PDB Molecule:fusion of n-terminal 17-mer peptide extension to PDBTitle: cocrystal structure of selected zinc finger dimer bound to2 dna 39 d1m2ka_ not modelled 57.7 14 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 40 d1xm5a_ not modelled 57.4 13 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Predicted metal-dependent hydrolase 41 c3nqzB_ not modelled 56.5 28 PDB header:hydrolase Chain: B: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed vibriolysin mcp-02 with e369a2 mutation 42 c3dl1A_ not modelled 56.5 27 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent hydrolase; PDBTitle: crystal structure of a putative metal-dependent hydrolase2 (yp_001336084.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 2.20 a resolution 43 c2eprA_ not modelled 55.9 23 PDB header:transcription Chain: A: PDB Molecule:poz-, at hook-, and zinc finger-containing PDBTitle: solution structure of the secound zinc finger domain of2 zinc finger protein 278 44 d1eaka2 not modelled 54.9 12 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 45 c1su3A_ not modelled 54.1 16 PDB header:hydrolase Chain: A: PDB Molecule:interstitial collagenase; PDBTitle: x-ray structure of human prommp-1: new insights into2 collagenase action 46 c3edhA_ not modelled 53.9 17 PDB header:hydrolase Chain: A: PDB Molecule:bone morphogenetic protein 1; PDBTitle: crystal structure of bone morphogenetic protein 1 protease2 domain in complex with partially bound dmso 47 d1sata2 not modelled 51.2 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 48 d1u4ga_ not modelled 49.3 28 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 49 d1eb6a_ not modelled 48.4 19 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Fungal zinc peptidase 50 d2csha1 not modelled 46.2 29 Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2 51 d1cgla_ not modelled 45.5 46 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 52 d1cxva_ not modelled 45.0 46 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 53 d2qtva5 not modelled 44.1 9 Fold:Rubredoxin-like Superfamily:Zn-finger domain of Sec23/24 Family:Zn-finger domain of Sec23/24 54 c1xaxA_ not modelled 43.8 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical upf0054 protein hi0004; PDBTitle: nmr structure of hi0004, a putative essential gene product2 from haemophilus influenzae 55 d1hfca_ not modelled 43.5 46 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 56 c3pkiF_ not modelled 43.4 17 PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose 57 d1xuca1 not modelled 43.3 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 58 d1rm8a_ not modelled 43.1 46 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 59 c2xs4A_ not modelled 42.8 46 PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium 60 d1q3aa_ not modelled 42.0 46 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 61 c2c6nA_ not modelled 41.7 12 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:angiotensin-converting enzyme, somatic isoform; PDBTitle: structure of human somatic angiontensin-i converting enzyme n domain2 with lisinopril 62 d1hv5a_ not modelled 41.5 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 63 d1qiba_ not modelled 40.6 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 64 d1i76a_ not modelled 40.3 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 65 c2adrA_ not modelled 40.1 28 PDB header:transcription regulation Chain: A: PDB Molecule:adr1; PDBTitle: adr1 dna-binding domain from saccharomyces cerevisiae, nmr,2 25 structures 66 d1g9ka2 not modelled 39.8 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 67 c3ba0A_ not modelled 39.7 11 PDB header:hydrolase Chain: A: PDB Molecule:macrophage metalloelastase; PDBTitle: crystal structure of full-length human mmp-12 68 d1y93a1 not modelled 39.7 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 69 d1hy7a_ not modelled 39.4 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 70 c3h0gL_ not modelled 39.4 23 PDB header:transcription Chain: L: PDB Molecule:dna-directed rna polymerases i, ii, and iii PDBTitle: rna polymerase ii from schizosaccharomyces pombe 71 c2ja6L_ not modelled 38.9 23 PDB header:transferase Chain: L: PDB Molecule:dna-directed rna polymerases i, ii, and iii 7.7 PDBTitle: cpd lesion containing rna polymerase ii elongation complex2 b 72 c2ythA_ not modelled 38.7 29 PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 224; PDBTitle: solution structure of the c2h2 type zinc finger (region 479-2 511) of human zinc finger protein 224 73 c2ytjA_ not modelled 38.1 18 PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 484; PDBTitle: solution structure of the c2h2 type zinc finger (region 771-2 803) of human zinc finger protein 484 74 c3b4rB_ not modelled 37.5 45 PDB header:hydrolase Chain: B: PDB Molecule:putative zinc metalloprotease mj0392; PDBTitle: site-2 protease from methanocaldococcus jannaschii 75 c2kdxA_ not modelled 37.5 16 PDB header:metal-binding protein Chain: A: PDB Molecule:hydrogenase/urease nickel incorporation protein PDBTitle: solution structure of hypa protein 76 c3lq0A_ not modelled 36.8 25 PDB header:hydrolase Chain: A: PDB Molecule:proastacin; PDBTitle: zymogen structure of crayfish astacin metallopeptidase 77 d2ovxa1 not modelled 36.5 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 78 c3glsC_ not modelled 36.5 19 PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3 79 d1x6ma_ not modelled 36.3 16 Fold:Mss4-like Superfamily:Mss4-like Family:Glutathione-dependent formaldehyde-activating enzyme, Gfa 80 c3k7lA_ not modelled 36.2 22 PDB header:hydrolase Chain: A: PDB Molecule:atragin; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 81 d1g12a_ not modelled 35.4 30 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Fungal zinc peptidase 82 d1asta_ not modelled 35.4 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Astacin 83 d1hova_ not modelled 35.1 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 84 c2i47A_ not modelled 35.1 29 PDB header:hydrolase Chain: A: PDB Molecule:adam 17; PDBTitle: crystal structure of catalytic domain of tace with inhibitor 85 d2gmga1 not modelled 34.8 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PF0610-like 86 d1kapp2 not modelled 34.7 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 87 d1bqqm_ not modelled 34.5 54 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 88 c2drpD_ not modelled 34.0 25 PDB header:transcription/dna Chain: D: PDB Molecule:protein (tramtrack dna-binding domain); PDBTitle: the crystal structure of a two zinc-finger peptide reveals2 an extension to the rules for zinc-finger/dna recognition 89 d2i47a1 not modelled 33.8 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TNF-alpha converting enzyme, TACE, catalytic domain 90 c1g2dC_ not modelled 33.8 21 PDB header:transcription/dna Chain: C: PDB Molecule:tata box zinc finger protein; PDBTitle: structure of a cys2his2 zinc finger/tata box complex (clone2 #2) 91 c3lqbA_ not modelled 33.6 42 PDB header:hydrolase Chain: A: PDB Molecule:loc792177 protein; PDBTitle: crystal structure of the hatching enzyme zhe1 from the zebrafish danio2 rerio 92 c1q14A_ not modelled 33.5 19 PDB header:hydrolase Chain: A: PDB Molecule:hst2 protein; PDBTitle: structure and autoregulation of the yeast hst2 homolog of sir2 93 d3cmna1 not modelled 32.7 26 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Caur0242-like 94 c3cmnA_ not modelled 32.7 26 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of a putative hydrolase with a novel fold2 from chloroflexus aurantiacus 95 c2dlkA_ not modelled 32.3 16 PDB header:dna binding protein Chain: A: PDB Molecule:novel protein; PDBTitle: solution structure of the first and the second zf-c2h22 domains of zinc finger protein 692 96 c1m2oA_ not modelled 32.3 9 PDB header:protein transport/signaling protein Chain: A: PDB Molecule:protein transport protein sec23; PDBTitle: crystal structure of the sec23-sar1 complex 97 d1fx7a3 not modelled 32.2 56 Fold:SH3-like barrel Superfamily:C-terminal domain of transcriptional repressors Family:FeoA-like 98 c2em3A_ not modelled 32.1 18 PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 28 homolog; PDBTitle: solution structure of the c2h2 type zinc finger (region 640-2 672) of human zinc finger protein 28 homolog 99 c3sksA_ not modelled 32.0 18 PDB header:hydrolase Chain: A: PDB Molecule:putative oligoendopeptidase f; PDBTitle: crystal structure of a putative oligoendopeptidase f from bacillus2 anthracis str. ames 100 c1x5wA_ not modelled 31.8 25 PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 64, isoforms 1; PDBTitle: solution structure of the c2h2 type zinc-binding domain of2 human zinc finger protein 64, isoforms 1 and 2 101 c2epsA_ not modelled 31.2 22 PDB header:transcription Chain: A: PDB Molecule:poz-, at hook-, and zinc finger-containing PDBTitle: solution structure of the 4th zinc finger domain of zinc2 finger protein 278 102 d1fbla2 not modelled 31.1 46 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 103 c3b8zB_ not modelled 31.1 55 PDB header:hydrolase Chain: B: PDB Molecule:protein adamts-5; PDBTitle: high resolution crystal structure of the catalytic domain2 of adamts-5 (aggrecanase-2) 104 c1un6D_ not modelled 30.4 23 PDB header:rna-binding protein/rna Chain: D: PDB Molecule:transcription factor iiia; PDBTitle: the crystal structure of a zinc finger - rna complex2 reveals two modes of molecular recognition 105 c2ktvA_ not modelled 30.4 11 PDB header:translation Chain: A: PDB Molecule:eukaryotic peptide chain release factor subunit 1; PDBTitle: human erf1 c-domain, "open" conformer 106 c2xhqA_ not modelled 29.9 25 PDB header:hydrolase Chain: A: PDB Molecule:archaemetzincin; PDBTitle: crystal structure of archaemetzincin (amza) from archaeoglobus2 fulgidus at 1.45 a resolution 107 c2v4bB_ not modelled 29.4 40 PDB header:hydrolase Chain: B: PDB Molecule:adamts-1; PDBTitle: crystal structure of human adamts-1 catalytic domain and2 cysteine-rich domain (apo-form) 108 c2emlA_ not modelled 29.4 26 PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 28 homolog; PDBTitle: solution structure of the c2h2 type zinc finger (region 752-2 784) of human zinc finger protein 28 homolog 109 d1r55a_ not modelled 29.4 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 110 d6rxna_ not modelled 29.3 16 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 111 d1s24a_ not modelled 29.3 16 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 112 c1s24A_ not modelled 29.3 16 PDB header:electron transport Chain: A: PDB Molecule:rubredoxin 2; PDBTitle: rubredoxin domain ii from pseudomonas oleovorans 113 d1x3za1 not modelled 29.3 21 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Transglutaminase core 114 c2eozA_ not modelled 29.2 18 PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 473; PDBTitle: solution structure of the c2h2 type zinc finger (region 809-2 841) of human zinc finger protein 473 115 d4rxna_ not modelled 29.2 13 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 116 d1iu5a_ not modelled 29.2 13 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 117 c2emwA_ not modelled 28.9 25 PDB header:transcription Chain: A: PDB Molecule:zinc finger protein 268; PDBTitle: solution structure of the c2h2 type zinc finger (region 301-2 331) of human zinc finger protein 268 118 d1q1aa_ not modelled 28.8 17 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 119 d1j36a_ not modelled 28.8 15 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Neurolysin-like 120 d1rb9a_ not modelled 28.6 16 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0