Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	I	L	L	A	F	K	A	E	P	D	A	G	M	L	A	E	K	E	W	Q	A	A	A	Q	G	K	S	G	P	D	I	S	L	L	R	S	L	L	G	A	D	E	Q	A	A	A	A	L	L	L	A	Q	R	K	N	G	T	P
Secondary structure
SS confidence
Disorder		?															?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?																				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	S	L	T	A	L	S	M	G	D	E	R	A	L	H	W	L	R	Y	L	M	A	L	G	F	E	E	A	V	L	L	E	T	A	A	D	L	R	F	A	P	E	F	V	A	R	H	I	A	E	W	Q	H	Q	N	P	L	D	L	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	T	G	C	Q	S	S	E	G	Q	N	G	Q	T	P	F	L	L	A	E	M	L	G	W	P	C	F	T	Q	V	E	R	F	T	L	D	A	L	F	I	T	L	E	Q	R	T	E	H	G	L	R	C	C	R	V	R	L	P	A	V
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	A	V	R	Q	C	G	E	V	A	L	P	V	P	G	M	R	Q	R	M	A	A	G	K	A	E	I	I	R	K	T	V	A	A	E	M	P	A	M	Q	C	L	Q	L	A	R	A	E	Q	R	R	G	A	T	L	I	D	G	Q	T
Secondary structure
SS confidence
Disorder								?	?							?							?	?	?										?	?	?	?	?	?						?	?	?	?	?	?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Sequence		V	A	E	K	A	Q	K	L	W	Q	D	Y	L	R	Q	R	M	Q	P
Secondary structure
SS confidence
Disorder																?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1efv chain B Region: 1 - 254 Aligned: 245 Modelled: 254 Confidence: 100.0% Identity: 21% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1efp chain B Region: 1 - 248 Aligned: 239 Modelled: 248 Confidence: 100.0% Identity: 24% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 3cls chain C domain 1 Region: 1 - 256 Aligned: 248 Modelled: 248 Confidence: 100.0% Identity: 23% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1o94 chain C Region: 1 - 227 Aligned: 220 Modelled: 227 Confidence: 100.0% Identity: 21% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1o94 chain D Region: 29 - 209 Aligned: 173 Modelled: 178 Confidence: 99.9% Identity: 11% PDB header:electron transport Chain: D: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: ternary complex between trimethylamine dehydrogenase and2 electron transferring flavoprotein Phyre2 PDB 3cls chain D domain 1 Region: 29 - 207 Aligned: 171 Modelled: 178 Confidence: 99.9% Identity: 11% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 3ih5 chain A Region: 25 - 222 Aligned: 186 Modelled: 197 Confidence: 99.8% Identity: 9% PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: crystal structure of electron transfer flavoprotein alpha-2 subunit from bacteroides thetaiotaomicron Phyre2 PDB 1efv chain A domain 1 Region: 39 - 195 Aligned: 144 Modelled: 157 Confidence: 99.6% Identity: 15% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1t9g chain R Region: 26 - 191 Aligned: 153 Modelled: 166 Confidence: 99.5% Identity: 16% PDB header:oxidoreductase, electron transport Chain: R: PDB Molecule:electron transfer flavoprotein alpha-subunit, PDBTitle: structure of the human mcad:etf complex Phyre2 PDB 1efp chain A domain 1 Region: 40 - 191 Aligned: 139 Modelled: 152 Confidence: 99.0% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: ETFP subunits Phyre2 PDB 1efp chain C Region: 40 - 231 Aligned: 173 Modelled: 191 Confidence: 99.0% Identity: 17% PDB header:electron transport Chain: C: PDB Molecule:protein (electron transfer flavoprotein); PDBTitle: electron transfer flavoprotein (etf) from paracoccus2 denitrificans Phyre2 PDB 3fet chain A Region: 37 - 195 Aligned: 139 Modelled: 159 Confidence: 98.7% Identity: 12% PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein subunit alpha related PDBTitle: crystal structure of the electron transfer flavoprotein subunit alpha2 related protein ta0212 from thermoplasma acidophilum Phyre2 PDB 3mt0 chain A Region: 40 - 142 Aligned: 98 Modelled: 103 Confidence: 90.7% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pa1789; PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1 Phyre2 PDB 1dkr chain B Region: 5 - 147 Aligned: 136 Modelled: 143 Confidence: 88.8% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. Phyre2 PDB 1tq8 chain A Region: 35 - 147 Aligned: 109 Modelled: 113 Confidence: 86.9% Identity: 9% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: Universal stress protein-like Phyre2 PDB 2z3v chain A domain 1 Region: 35 - 142 Aligned: 103 Modelled: 108 Confidence: 85.6% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Adenine nucleotide alpha hydrolases-like Family: Universal stress protein-like Phyre2 PDB 1w96 chain B Region: 37 - 148 Aligned: 107 Modelled: 112 Confidence: 84.5% Identity: 8% PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a Phyre2 PDB 1uan chain A Region: 42 - 122 Aligned: 81 Modelled: 81 Confidence: 84.4% Identity: 16% Fold: LmbE-like Superfamily: LmbE-like Family: LmbE-like Phyre2 PDB 3lpn chain B Region: 5 - 168 Aligned: 152 Modelled: 158 Confidence: 83.1% Identity: 11% PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp). Phyre2 PDB 3fh0 chain A Region: 39 - 147 Aligned: 103 Modelled: 109 Confidence: 82.9% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative universal stress protein kpn_01444; PDBTitle: crystal structure of putative universal stress protein kpn_01444 -2 atpase Phyre2 1 d1efvb_ 2 d1efpb_ 3 d3clsc1 4 d1o94c_ 5 c1o94D_ 6 d3clsd1 7 c3ih5A_ 8 d1efva1 9 c1t9gR_ 10 d1efpa1 11 c1efpC_ 12 c3fetA_ 13 c3mt0A_ 14 c1dkrB_ 15 d1tq8a_ 16 d2z3va1 17 c1w96B_ 18 d1uana_ 19 c3lpnB_ 20 c3fh0A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1efvb_ 100.0 21 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 2 d1efpb_ 100.0 24 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 3 d3clsc1 100.0 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 4 d1o94c_ 100.0 21 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 5 c1o94D_ 99.9 11 PDB header:electron transport Chain: D: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: ternary complex between trimethylamine dehydrogenase and2 electron transferring flavoprotein 6 d3clsd1 99.9 11 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 7 c3ih5A_ 99.8 9 PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein alpha-subunit; PDBTitle: crystal structure of electron transfer flavoprotein alpha-2 subunit from bacteroides thetaiotaomicron 8 d1efva1 99.6 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 9 c1t9gR_ 99.5 16 PDB header:oxidoreductase, electron transport Chain: R: PDB Molecule:electron transfer flavoprotein alpha-subunit, PDBTitle: structure of the human mcad:etf complex 10 d1efpa1 99.0 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 11 c1efpC_ 99.0 17 PDB header:electron transport Chain: C: PDB Molecule:protein (electron transfer flavoprotein); PDBTitle: electron transfer flavoprotein (etf) from paracoccus2 denitrificans 12 c3fetA_ 98.7 12 PDB header:electron transport Chain: A: PDB Molecule:electron transfer flavoprotein subunit alpha related PDBTitle: crystal structure of the electron transfer flavoprotein subunit alpha2 related protein ta0212 from thermoplasma acidophilum 13 c3mt0A_ 90.7 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein pa1789; PDBTitle: the crystal structure of a functionally unknown protein pa1789 from2 pseudomonas aeruginosa pao1 14 c1dkrB_ 88.8 13 PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. 15 d1tq8a_ 86.9 9 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 16 d2z3va1 85.6 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 17 c1w96B_ 84.5 8 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a 18 d1uana_ 84.4 16 Fold:LmbE-like Superfamily:LmbE-like Family:LmbE-like 19 c3lpnB_ 83.1 11 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp). 20 c3fh0A_ 82.9 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative universal stress protein kpn_01444; PDBTitle: crystal structure of putative universal stress protein kpn_01444 -2 atpase 21 d1iowa1 not modelled 81.8 15 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:D-Alanine ligase N-terminal domain 22 c2c4kD_ not modelled 81.4 10 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 23 c3efhB_ not modelled 81.0 13 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 24 c2ixdB_ not modelled 80.8 16 PDB header:hydrolase Chain: B: PDB Molecule:lmbe-related protein; PDBTitle: crystal structure of the putative deacetylase bc1534 from2 bacilus cereus 25 c3fg9B_ not modelled 79.3 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein of universal stress protein uspa family; PDBTitle: the crystal structure of an universal stress protein uspa2 family protein from lactobacillus plantarum wcfs1 26 c3hgmD_ not modelled 78.2 19 PDB header:signaling protein Chain: D: PDB Molecule:universal stress protein tead; PDBTitle: universal stress protein tead from the trap transporter2 teaabc of halomonas elongata 27 d2ji7a1 not modelled 77.8 20 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 28 d1ozha1 not modelled 75.7 11 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 29 d1q77a_ not modelled 74.0 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 30 c2vu2D_ not modelled 73.0 12 PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: biosynthetic thiolase from z. ramigera. complex with s-2 pantetheine-11-pivalate. 31 c2pfsA_ not modelled 69.0 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: crystal structure of universal stress protein from nitrosomonas2 europaea 32 c2v4wB_ not modelled 68.5 13 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, PDBTitle: crystal structure of human mitochondrial 3-hydroxy-3-2 methylglutaryl-coenzyme a synthase 2 (hmgcs2) 33 c2dy0A_ not modelled 68.2 13 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 34 d2djia1 not modelled 65.6 20 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 35 c1u9yD_ not modelled 65.4 12 PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii 36 c2ebdB_ not modelled 64.9 16 PDB header:transferase Chain: B: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase iii2 from aquifex aeolicus vf5 37 d1u11a_ not modelled 64.4 21 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 38 c2fw9A_ not modelled 64.4 22 PDB header:lyase Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: structure of pure (n5-carboxyaminoimidazole ribonucleotide mutase)2 h59f from the acidophilic bacterium acetobacter aceti, at ph 8 39 d1xmpa_ not modelled 63.3 19 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 40 c1kh2D_ not modelled 61.8 14 PDB header:ligase Chain: D: PDB Molecule:argininosuccinate synthetase; PDBTitle: crystal structure of thermus thermophilus hb82 argininosuccinate synthetase in complex with atp 41 c1zq1B_ not modelled 61.3 15 PDB header:lyase Chain: B: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: structure of gatde trna-dependent amidotransferase from2 pyrococcus abyssi 42 d1w0ma_ not modelled 61.0 15 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 43 c2is8A_ not modelled 60.7 18 PDB header:structural protein Chain: A: PDB Molecule:molybdopterin biosynthesis enzyme, moab; PDBTitle: crystal structure of the molybdopterin biosynthesis enzyme moab2 (ttha0341) from thermus theromophilus hb8 44 c3loqA_ not modelled 60.5 14 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:universal stress protein; PDBTitle: the crystal structure of a universal stress protein from2 archaeoglobus fulgidus dsm 4304 45 c3ss6B_ not modelled 60.2 13 PDB header:transferase Chain: B: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystal structure of the bacillus anthracis acetyl-coa2 acetyltransferase 46 c2iikA_ not modelled 59.2 9 PDB header:transferase Chain: A: PDB Molecule:3-ketoacyl-coa thiolase, peroxisomal; PDBTitle: crystal structure of human peroxisomal acetyl-coa acyl transferase 12 (acaa1) 47 d1jlja_ not modelled 56.4 18 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 48 d1ybha1 not modelled 56.3 9 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 49 c3il5D_ not modelled 56.0 8 PDB header:transferase Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: structure of e. faecalis fabh in complex with 2-({4-bromo-3-2 [(diethylamino)sulfonyl]benzoyl}amino)benzoic acid 50 c3lp6D_ not modelled 55.5 17 PDB header:lyase Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit; PDBTitle: crystal structure of rv3275c-e60a from mycobacterium tuberculosis at2 1.7a resolution 51 d1rqba2 not modelled 55.3 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 52 c3cwcB_ not modelled 52.8 24 PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 53 d1znna1 not modelled 52.5 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:PdxS-like 54 c1znnF_ not modelled 52.5 20 PDB header:biosynthetic protein Chain: F: PDB Molecule:plp synthase; PDBTitle: structure of the synthase subunit of plp synthase 55 c3trhI_ not modelled 52.5 11 PDB header:lyase Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii 56 c2qnxA_ not modelled 52.2 14 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of the complex between the mycobacterium beta-2 ketoacyl-acyl carrier protein synthase iii (fabh) and 11-3 [(decyloxycarbonyl)dithio]-undecanoic acid 57 d1wv2a_ not modelled 51.4 26 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 58 d1o4va_ not modelled 51.2 16 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 59 c2ywxA_ not modelled 49.9 21 PDB header:lyase Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase catalytic subunit; PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase2 catalytic subunit from methanocaldococcus jannaschii 60 c1rr2A_ not modelled 49.8 16 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 61 c2x3eA_ not modelled 49.4 13 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] synthase 3; PDBTitle: crystal structure of 3-oxoacyl-(acyl carrier protein)2 synthase iii, fabh from pseudomonas aeruginosa pao1 62 d1miob_ not modelled 49.2 18 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 63 d1zpda1 not modelled 48.6 10 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 64 d1qcza_ not modelled 48.5 16 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 65 d1di6a_ not modelled 47.4 16 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 66 c2z6jB_ not modelled 47.2 15 PDB header:oxidoreductase Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii; PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor 67 c3orsD_ not modelled 46.9 15 PDB header:isomerase,biosynthetic protein Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus 68 d1l1qa_ not modelled 46.3 10 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 69 d2ihta1 not modelled 46.1 20 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 70 d1y0ba1 not modelled 44.6 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 71 c3dloC_ not modelled 44.4 16 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:universal stress protein; PDBTitle: structure of universal stress protein from archaeoglobus fulgidus 72 d1vcfa1 not modelled 43.8 19 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 73 d1o57a2 not modelled 42.9 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 74 c1o57A_ not modelled 42.9 15 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 75 c3lyhB_ not modelled 42.7 4 PDB header:lyase Chain: B: PDB Molecule:cobalamin (vitamin b12) biosynthesis cbix protein; PDBTitle: crystal structure of putative cobalamin (vitamin b12) biosynthesis2 cbix protein (yp_958415.1) from marinobacter aquaeolei vt8 at 1.60 a3 resolution 76 c3pdiG_ not modelled 42.2 16 PDB header:protein binding Chain: G: PDB Molecule:nitrogenase mofe cofactor biosynthesis protein nife; PDBTitle: precursor bound nifen 77 c1ub7A_ not modelled 42.2 13 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier protein] synthase; PDBTitle: the crystal analysis of beta-keroacyl-[acyl carrier protein] synthase2 iii (fabh)from thermus thermophilus. 78 c2p8uB_ not modelled 41.8 9 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, cytoplasmic; PDBTitle: crystal structure of human 3-hydroxy-3-methylglutaryl coa synthase i 79 d1jcna1 not modelled 41.4 12 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 80 d2ez9a1 not modelled 41.1 17 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 81 d1g2qa_ not modelled 40.7 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 82 c1mzjB_ not modelled 40.5 11 PDB header:transferase Chain: B: PDB Molecule:beta-ketoacylsynthase iii; PDBTitle: crystal structure of the priming beta-ketosynthase from the2 r1128 polyketide biosynthetic pathway 83 d1qh8a_ not modelled 39.7 19 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 84 c2htmB_ not modelled 39.4 20 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 85 d1ovma1 not modelled 38.8 2 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 86 c3s29C_ not modelled 37.7 28 PDB header:transferase Chain: C: PDB Molecule:sucrose synthase 1; PDBTitle: the crystal structure of sucrose synthase-1 from arabidopsis thaliana2 and its functional implications. 87 c2ibyD_ not modelled 37.3 11 PDB header:transferase Chain: D: PDB Molecule:acetyl-coa acetyltransferase; PDBTitle: crystallographic and kinetic studies of human mitochondrial2 acetoacetyl-coa thiolase (t2): the importance of potassium and3 chloride for its structure and function 88 d1q6za1 not modelled 37.3 16 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 89 d1xm3a_ not modelled 37.3 22 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 90 d1q74a_ not modelled 36.7 18 Fold:LmbE-like Superfamily:LmbE-like Family:LmbE-like 91 c2pjkA_ not modelled 36.4 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:178aa long hypothetical molybdenum cofactor PDBTitle: structure of hypothetical molybdenum cofactor biosynthesis2 protein b from sulfolobus tokodaii 92 d1zn7a1 not modelled 35.9 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 93 c1kbiB_ not modelled 35.9 16 PDB header:oxidoreductase Chain: B: PDB Molecule:cytochrome b2; PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme 94 c1olsB_ not modelled 35.1 9 PDB header:oxidoreductase Chain: B: PDB Molecule:2-oxoisovalerate dehydrogenase beta subunit; PDBTitle: roles of his291-alpha and his146-beta' in the reductive2 acylation reaction catalyzed by human branched-chain3 alpha-ketoacid dehydrogenase 95 d1kbia1 not modelled 34.8 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 96 c2nrrA_ not modelled 34.7 15 PDB header:hydrolase Chain: A: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the c-terminal rnaseh endonuclase2 domain of uvrc 97 d1hc7a1 not modelled 34.4 13 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 98 d1v4va_ not modelled 34.1 17 Fold:UDP-Glycosyltransferase/glycogen phosphorylase Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase Family:UDP-N-acetylglucosamine 2-epimerase 99 d1uuya_ not modelled 34.1 17 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 100 d1hg3a_ not modelled 32.5 13 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 101 d1jq5a_ not modelled 32.2 9 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 102 c1wl5A_ not modelled 32.0 12 PDB header:transferase Chain: A: PDB Molecule:acetyl-coenzyme a acetyltransferase 2; PDBTitle: human cytosolic acetoacetyl-coa thiolase 103 d2gm3a1 not modelled 32.0 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:Universal stress protein-like 104 c3rggD_ not modelled 30.9 15 PDB header:lyase Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase, pure protein; PDBTitle: crystal structure of treponema denticola pure bound to air 105 c3fiuD_ not modelled 30.8 16 PDB header:ligase Chain: D: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: structure of nmn synthetase from francisella tularensis 106 c1zfjA_ not modelled 30.1 14 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 107 c3qjaA_ not modelled 30.1 14 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 108 d1hnja1 not modelled 29.7 13 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 109 c2vbgB_ not modelled 29.2 15 PDB header:lyase Chain: B: PDB Molecule:branched-chain alpha-ketoacid decarboxylase; PDBTitle: the complex structure of the branched-chain keto acid2 decarboxylase (kdca) from lactococcus lactis with 2r-1-3 hydroxyethyl-deazathdp 110 c3s3tD_ not modelled 29.0 11 PDB header:chaperone Chain: D: PDB Molecule:nucleotide-binding protein, universal stress protein uspa PDBTitle: universal stress protein uspa from lactobacillus plantarum 111 c3gidB_ not modelled 28.8 11 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: the biotin carboxylase (bc) domain of human acetyl-coa2 carboxylase 2 (acc2) in complex with soraphen a 112 c3gwaA_ not modelled 28.7 16 PDB header:transferase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) synthase iii; PDBTitle: 1.6 angstrom crystal structure of 3-oxoacyl-(acyl-carrier-protein)2 synthase iii 113 c3bo9B_ not modelled 28.5 20 PDB header:oxidoreductase Chain: B: PDB Molecule:putative nitroalkan dioxygenase; PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution 114 c2f9aA_ not modelled 28.1 9 PDB header:transferase Chain: A: PDB Molecule:3-hydroxy-3-methylglutaryl coenzyme a synthase 1; PDBTitle: hmg-coa synthase from brassica juncea in complex with f-244 115 d1e0ta2 not modelled 27.5 8 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 116 c1dl5A_ not modelled 27.4 15 PDB header:transferase Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase; PDBTitle: protein-l-isoaspartate o-methyltransferase 117 d1lbqa_ not modelled 27.2 9 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 118 d2c4ka1 not modelled 27.1 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 119 d1tqxa_ not modelled 26.1 7 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 120 d1vdma1 not modelled 26.0 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0