Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP24082
DateThu Jan 5 11:40:43 GMT 2012
Unique Job IDc4293149cc0b3a3a

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2r09A_
Top template information
PDB header:signaling protein
Chain: A: PDB Molecule:cytohesin-3;
PDBTitle: crystal structure of autoinhibited form of grp1 arf gtpase exchange2 factor
Confidence and coverage
Confidence: 70.9% Coverage: 7%
45 residues ( 7% of your sequence) have been modelled with 70.9% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKRILPLILALVAGMAQADSNSDYRAGSDFAHQIKGQGSSSIQGFKPQESIPGYNANPDE
Secondary structure 
SS confidence 
Disorder  ???
??????
?????????????????
??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  TKYYGGVTAGGDGGLKNDGTTEWATGETGKTITESFMNKPKDILSPDAPFIQTGRDVVNR
Secondary structure 
SS confidence 
Disorder  ??????????????????????????
?
?
?
????????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ADSIVGNTGQQCSAQEISRSEYTNYTCERDLQVEQYCTRTARMELQGSTTWETRTLEYEM
Secondary structure 
SS confidence 
Disorder 
?
?
??
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  SQLPAREVNGQYVVSITSPVTGEIVDAHYSWSRTYLQKSVPMTITVLGTPLSWNAKYSAD
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  ASFTPVQKTLTAGVAFTSSHPVRVGNTKFKRHTAMKLRLVVRVKKASYTPYVVWSESCPF
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  SKELGKLTKTECTEAGGNRTLVKDGQSYSMYQSCWAYRDTYVTQSADKGTCQTYTDNPAC
Secondary structure 
SS confidence 
Disorder  ????
????
?
?
?
?
?
????
????
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  TLVSHQCAFYSEEGACLHEYATYSCESKTSGKVMVCGGDVFCLDGECDKAQSGKSNDFAE
Secondary structure 
SS confidence 
Disorder  ?????????????
????????????
????
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  AVSQLAALAAAGKDVAALNGVDVRAFTGQAKFCKKAAAGYSNCCKDSGWGQDIGLAKCSS
Secondary structure 
SS confidence 
Disorder 
?
??
?
?
??
??
?
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  DEKALAKAKSNKLTVSVGEFCSKKVLGVCLEKKRSYCQFDSKLAQIVQQQGRNGQLRISF
Secondary structure 
SS confidence 
Disorder 
?
?
?
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  GSAKHPDCRGITVDELQKIQFNRLDFTNFYEDLMNNQKIPDSGVLTQKVKEQIADQLKQA
Secondary structure 
SS confidence 
Disorder 
??
???????
??
Disorder confidence 
 
   ..
Sequence  GQ
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2r09 chain A

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 70.9%
Identity: 11%
PDB header:signaling protein
Chain: A: PDB Molecule:cytohesin-3;
PDBTitle: crystal structure of autoinhibited form of grp1 arf gtpase exchange2 factor

Phyre2

PDB 1nxh chain A

3D model

Region: 550 - 589
Aligned: 39
Modelled: 40
Confidence: 69.1%
Identity: 23%
Fold: Hypothetical protein MTH393
Superfamily: Hypothetical protein MTH393
Family: Hypothetical protein MTH393

Phyre2

PDB 1re0 chain B

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 67.6%
Identity: 11%
Fold: alpha-alpha superhelix
Superfamily: Sec7 domain
Family: Sec7 domain

Phyre2

PDB 1xsz chain A domain 1

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 67.1%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: Sec7 domain
Family: Sec7 domain

Phyre2

PDB 1pbv chain A

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 66.6%
Identity: 11%
Fold: alpha-alpha superhelix
Superfamily: Sec7 domain
Family: Sec7 domain

Phyre2

PDB 1ku1 chain A

3D model

Region: 556 - 597
Aligned: 42
Modelled: 42
Confidence: 65.9%
Identity: 12%
Fold: alpha-alpha superhelix
Superfamily: Sec7 domain
Family: Sec7 domain

Phyre2

PDB 2r09 chain A domain 1

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 65.3%
Identity: 11%
Fold: alpha-alpha superhelix
Superfamily: Sec7 domain
Family: Sec7 domain

Phyre2

PDB 1r8s chain E

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 63.7%
Identity: 11%
Fold: alpha-alpha superhelix
Superfamily: Sec7 domain
Family: Sec7 domain

Phyre2

PDB 2bkx chain B

3D model

Region: 523 - 566
Aligned: 34
Modelled: 44
Confidence: 58.3%
Identity: 24%
PDB header:hydrolase
Chain: B: PDB Molecule:glucosamine-6-phosphate deaminase;
PDBTitle: structure and kinetics of a monomeric glucosamine-6-2 phosphate deaminase: missing link of the nagb superfamily

Phyre2

PDB 1xsz chain A

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 56.5%
Identity: 13%
PDB header:signaling protein
Chain: A: PDB Molecule:guanine nucleotide exchange protein;
PDBTitle: the structure of ralf

Phyre2

PDB 1a8r chain A

3D model

Region: 495 - 536
Aligned: 30
Modelled: 42
Confidence: 51.9%
Identity: 30%
Fold: T-fold
Superfamily: Tetrahydrobiopterin biosynthesis enzymes-like
Family: GTP cyclohydrolase I

Phyre2

PDB 1bc9 chain A

3D model

Region: 556 - 600
Aligned: 45
Modelled: 45
Confidence: 43.4%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: Sec7 domain
Family: Sec7 domain

Phyre2

PDB 2ply chain B

3D model

Region: 543 - 601
Aligned: 59
Modelled: 59
Confidence: 43.2%
Identity: 19%
PDB header:translation/rna
Chain: B: PDB Molecule:selenocysteine-specific elongation factor;
PDBTitle: structure of the mrna binding fragment of elongation factor2 selb in complex with secis rna.

Phyre2

PDB 1is7 chain F

3D model

Region: 521 - 536
Aligned: 16
Modelled: 16
Confidence: 43.0%
Identity: 50%
PDB header:hydrolase/protein binding
Chain: F: PDB Molecule:gtp cyclohydrolase i;
PDBTitle: crystal structure of rat gtpchi/gfrp stimulatory complex

Phyre2

PDB 1wpl chain A

3D model

Region: 521 - 536
Aligned: 16
Modelled: 16
Confidence: 43.0%
Identity: 50%
Fold: T-fold
Superfamily: Tetrahydrobiopterin biosynthesis enzymes-like
Family: GTP cyclohydrolase I

Phyre2

PDB 1wm9 chain D

3D model

Region: 521 - 536
Aligned: 16
Modelled: 16
Confidence: 42.4%
Identity: 44%
PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase i;
PDBTitle: structure of gtp cyclohydrolase i from thermus thermophilus hb8

Phyre2

PDB 1wur chain A domain 1

3D model

Region: 521 - 536
Aligned: 16
Modelled: 16
Confidence: 42.4%
Identity: 44%
Fold: T-fold
Superfamily: Tetrahydrobiopterin biosynthesis enzymes-like
Family: GTP cyclohydrolase I

Phyre2

PDB 2kri chain B

3D model

Region: 382 - 406
Aligned: 25
Modelled: 25
Confidence: 35.8%
Identity: 32%
PDB header:protein binding/endocytosis
Chain: B: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: structure of a complex between domain v of beta2-2 glycoprotein i and the fourth ligand-binding module from3 ldlr determined with haddock

Phyre2

PDB 2fcw chain B domain 2

3D model

Region: 382 - 406
Aligned: 25
Modelled: 25
Confidence: 35.7%
Identity: 32%
Fold: LDL receptor-like module
Superfamily: LDL receptor-like module
Family: LDL receptor-like module

Phyre2

PDB 2fcw chain B domain 1

3D model

Region: 382 - 406
Aligned: 25
Modelled: 25
Confidence: 33.0%
Identity: 32%
Fold: LDL receptor-like module
Superfamily: LDL receptor-like module
Family: LDL receptor-like module

Phyre2
1
c2r09A_
2
d1nxha_
3
d1re0b_
4
d1xsza1
5
d1pbva_
6
d1ku1a_
7
d2r09a1
8
d1r8se_
9
c2bkxB_
10
c1xszA_
11
d1a8ra_
12
d1bc9a_
13
c2plyB_
14
c1is7F_
15
d1wpla_
16
c1wm9D_
17
d1wura1
18
c2kriB_
19
d2fcwb2
20
d2fcwb1
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
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91
92
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94
95
96
97
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99



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2r09A_
70.9 11 PDB header:signaling protein
Chain: A: PDB Molecule:cytohesin-3;
PDBTitle: crystal structure of autoinhibited form of grp1 arf gtpase exchange2 factor
2d1nxha_
69.1 23 Fold:Hypothetical protein MTH393
Superfamily:Hypothetical protein MTH393
Family:Hypothetical protein MTH393
3d1re0b_
67.6 11 Fold:alpha-alpha superhelix
Superfamily:Sec7 domain
Family:Sec7 domain
4d1xsza1
67.1 13 Fold:alpha-alpha superhelix
Superfamily:Sec7 domain
Family:Sec7 domain
5d1pbva_
66.6 11 Fold:alpha-alpha superhelix
Superfamily:Sec7 domain
Family:Sec7 domain
6d1ku1a_
65.9 12 Fold:alpha-alpha superhelix
Superfamily:Sec7 domain
Family:Sec7 domain
7d2r09a1
65.3 11 Fold:alpha-alpha superhelix
Superfamily:Sec7 domain
Family:Sec7 domain
8d1r8se_
63.7 11 Fold:alpha-alpha superhelix
Superfamily:Sec7 domain
Family:Sec7 domain
9c2bkxB_
58.3 24 PDB header:hydrolase
Chain: B: PDB Molecule:glucosamine-6-phosphate deaminase;
PDBTitle: structure and kinetics of a monomeric glucosamine-6-2 phosphate deaminase: missing link of the nagb superfamily
10c1xszA_
56.5 13 PDB header:signaling protein
Chain: A: PDB Molecule:guanine nucleotide exchange protein;
PDBTitle: the structure of ralf
11d1a8ra_
51.9 30 Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:GTP cyclohydrolase I
12d1bc9a_
43.4 13 Fold:alpha-alpha superhelix
Superfamily:Sec7 domain
Family:Sec7 domain
13c2plyB_
43.2 19 PDB header:translation/rna
Chain: B: PDB Molecule:selenocysteine-specific elongation factor;
PDBTitle: structure of the mrna binding fragment of elongation factor2 selb in complex with secis rna.
14c1is7F_
43.0 50 PDB header:hydrolase/protein binding
Chain: F: PDB Molecule:gtp cyclohydrolase i;
PDBTitle: crystal structure of rat gtpchi/gfrp stimulatory complex
15d1wpla_
43.0 50 Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:GTP cyclohydrolase I
16c1wm9D_
42.4 44 PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase i;
PDBTitle: structure of gtp cyclohydrolase i from thermus thermophilus hb8
17d1wura1
42.4 44 Fold:T-fold
Superfamily:Tetrahydrobiopterin biosynthesis enzymes-like
Family:GTP cyclohydrolase I
18c2kriB_
35.8 32 PDB header:protein binding/endocytosis
Chain: B: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: structure of a complex between domain v of beta2-2 glycoprotein i and the fourth ligand-binding module from3 ldlr determined with haddock
19d2fcwb2
35.7 32 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
20d2fcwb1
33.0 32 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
21c3a7qB_
not modelled 32.9 28 PDB header:signaling protein
Chain: B: PDB Molecule:low-density lipoprotein receptor-related protein 8;
PDBTitle: structural basis for specific recognition of reelin by its receptors
22c1wloA_
not modelled 30.6 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sufe protein;
PDBTitle: solution structure of the hypothetical protein from thermus2 thermophilus hb8
23d1ni7a_
not modelled 30.3 20 Fold:SufE/NifU
Superfamily:SufE/NifU
Family:SufE-like
24c1f8zA_
not modelled 29.7 16 PDB header:lipid binding protein
Chain: A: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: nmr structure of the sixth ligand-binding module of the ldl2 receptor
25d1f8za_
not modelled 29.7 16 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
26c1d2jA_
not modelled 28.9 16 PDB header:signaling protein
Chain: A: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: ldl receptor ligand-binding module 6
27d1ajja_
not modelled 28.3 24 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
28d1n7da7
not modelled 28.1 32 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
29c3a23A_
not modelled 23.2 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative secreted alpha-galactosidase;
PDBTitle: crystal structure of beta-l-arabinopyranosidase complexed with d-2 galactose
30c2ekwC_
not modelled 23.1 21 PDB header:contractile protein
Chain: C: PDB Molecule:myosin catalytic light chain lc-1, mantle muscle;
PDBTitle: the crystal structure of squid myosin s1 in the presence of2 so4 2-
31d1j8ea_
not modelled 23.1 28 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
32c4a18U_
not modelled 22.8 33 PDB header:ribosome
Chain: U: PDB Molecule:rpl13;
PDBTitle: t.thermophila 60s ribosomal subunit in complex with initiation2 factor 6. this file contains 26s rrna and proteins of molecule 1
33c3u5eL_
not modelled 22.2 27 PDB header:ribosome
Chain: L: PDB Molecule:60s ribosomal protein l13-a;
PDBTitle: the structure of the eukaryotic ribosome at 3.0 resolution
34d2enda_
not modelled 22.1 13 Fold:T4 endonuclease V
Superfamily:T4 endonuclease V
Family:T4 endonuclease V
35c2eboB_
not modelled 21.6 14 PDB header:envelope glycoprotein
Chain: B: PDB Molecule:ebola virus envelope glycoprotein;
PDBTitle: core structure of gp2 from ebola virus
36d1e7la1
not modelled 21.4 12 Fold:LEM/SAP HeH motif
Superfamily:Recombination endonuclease VII, C-terminal and dimerization domains
Family:Recombination endonuclease VII, C-terminal and dimerization domains
37d2gtln2
not modelled 21.0 24 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
38c1tpgA_
not modelled 20.1 12 PDB header:plasminogen activation
Chain: A: PDB Molecule:t-plasminogen activator f1-g;
PDBTitle: f1-g module pair residues 1-91 (c83s) of tissue-type2 plasminogen activator (t-pa) (nmr, 298k, ph2.95,3 representative structure)
39d2gtlm2
not modelled 18.9 24 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
40c3fwcO_
not modelled 18.6 18 PDB header:cell cycle, transcription
Chain: O: PDB Molecule:protein sus1;
PDBTitle: sac3:sus1:cdc31 complex
41c1ponB_
not modelled 16.1 33 PDB header:calcium-binding protein
Chain: B: PDB Molecule:troponin c;
PDBTitle: site iii-site iv troponin c heterodimer, nmr
42c3qfwB_
not modelled 16.0 27 PDB header:lyase
Chain: B: PDB Molecule:ribulose-1,5-bisphosphate carboxylase/oxygenase large
PDBTitle: crystal structure of rubisco-like protein from rhodopseudomonas2 palustris
43d1qwoa_
not modelled 16.0 23 Fold:Phosphoglycerate mutase-like
Superfamily:Phosphoglycerate mutase-like
Family:Histidine acid phosphatase
44d1bjfa_
not modelled 15.9 18 Fold:EF Hand-like
Superfamily:EF-hand
Family:Calmodulin-like
45d2gtlo2
not modelled 15.7 32 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
46c1mgpA_
not modelled 15.6 12 PDB header:lipid binding protein
Chain: A: PDB Molecule:hypothetical protein tm841;
PDBTitle: hypothetical protein tm841 from thermotoga maritima reveals2 fatty acid binding function
47d1mgpa_
not modelled 15.6 12 Fold:DAK1/DegV-like
Superfamily:DAK1/DegV-like
Family:DegV-like
48d1f7ea_
not modelled 15.4 13 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:EGF/Laminin
Family:EGF-type module
49c1tt3A_
not modelled 15.2 39 PDB header:toxin
Chain: A: PDB Molecule:omega-conotoxin mviia;
PDBTitle: nmr soulution structure of omega-conotoxin [k10]mviia
50d1g8ia_
not modelled 15.1 23 Fold:EF Hand-like
Superfamily:EF-hand
Family:Calmodulin-like
51d1mzga_
not modelled 14.8 8 Fold:SufE/NifU
Superfamily:SufE/NifU
Family:SufE-like
52c3h5cB_
not modelled 14.8 28 PDB header:hydrolase inhibitor/blood clotting
Chain: B: PDB Molecule:vitamin k-dependent protein z;
PDBTitle: x-ray structure of protein z-protein z inhibitor complex
53c2xzmS_
not modelled 14.6 17 PDB header:ribosome
Chain: S: PDB Molecule:rps15e;
PDBTitle: crystal structure of the eukaryotic 40s ribosomal2 subunit in complex with initiation factor 1. this file3 contains the 40s subunit and initiation factor for4 molecule 1
54d1wdcc_
not modelled 14.5 12 Fold:EF Hand-like
Superfamily:EF-hand
Family:Calmodulin-like
55c2xgvA_
not modelled 13.9 11 PDB header:viral protein
Chain: A: PDB Molecule:psiv capsid n-terminal domain;
PDBTitle: structure of the n-terminal domain of capsid protein from2 rabbit endogenous lentivirus (relik)
56c2lgpA_
not modelled 13.4 33 PDB header:protein binding
Chain: A: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: solution structure of la45 from ldlr
57c3gmxB_
not modelled 13.3 35 PDB header:protein binding
Chain: B: PDB Molecule:blp;
PDBTitle: crystal structure of beta-lactamse inhibitory protein-like2 protein (blp) at 1.05 angstrom resolution
58d2bbga_
not modelled 13.2 27 Fold:Amb V allergen
Superfamily:Amb V allergen
Family:Amb V allergen
59d1cixa_
not modelled 12.6 46 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:omega toxin-like
Family:Spider toxins
60c1g6uB_
not modelled 12.3 27 PDB header:de novo protein
Chain: B: PDB Molecule:domain swapped dimer;
PDBTitle: crystal structure of a domain swapped dimer
61c3gmvX_
not modelled 12.3 26 PDB header:protein binding
Chain: X: PDB Molecule:beta-lactamase inhibitory protein blip-i;
PDBTitle: crystal structure of beta-lactamse inhibitory protein-i2 (blip-i) in apo form
62c2i1pA_
not modelled 12.2 21 PDB header:ligand binding protein
Chain: A: PDB Molecule:low-density lipoprotein receptor-related protein
PDBTitle: solution structure of the twelfth cysteine-rich ligand-2 binding repeat in rat megalin
63c2jm4A_
not modelled 12.1 16 PDB header:signaling protein
Chain: A: PDB Molecule:relaxin receptor 1;
PDBTitle: the solution nmr structure of the relaxin (rxfp1) receptor2 ldla module.
64c3pbiA_
not modelled 12.1 23 PDB header:hydrolase
Chain: A: PDB Molecule:invasion protein;
PDBTitle: structure of the peptidoglycan hydrolase ripb (rv1478) from2 mycobacterium tuberculosis at 1.6 resolution
65d2o8ra1
not modelled 12.0 13 Fold:Spectrin repeat-like
Superfamily:PPK N-terminal domain-like
Family:PPK N-terminal domain-like
66d1whra_
not modelled 11.9 15 Fold:IF3-like
Superfamily:R3H domain
Family:R3H domain
67c2k1gA_
not modelled 11.8 27 PDB header:lipoprotein
Chain: A: PDB Molecule:lipoprotein spr;
PDBTitle: solution nmr structure of lipoprotein spr from escherichia coli k12.2 northeast structural genomics target er541-37-162
68c2on3A_
not modelled 11.6 14 PDB header:lyase
Chain: A: PDB Molecule:ornithine decarboxylase;
PDBTitle: a structural insight into the inhibition of human and2 leishmania donovani ornithine decarboxylases by 3-aminooxy-3 1-aminopropane
69c2fcdA_
not modelled 11.5 22 PDB header:cell cycle
Chain: A: PDB Molecule:myosin light chain 1;
PDBTitle: solution structure of n-lobe myosin light chain from2 saccharomices cerevisiae
70c2xivA_
not modelled 11.3 21 PDB header:structural protein
Chain: A: PDB Molecule:hypothetical invasion protein;
PDBTitle: structure of rv1477, hypothetical invasion protein of2 mycobacterium tuberculosis
71c2knyA_
not modelled 11.1 32 PDB header:metal binding protein
Chain: A: PDB Molecule:lrp-1, linker, apo-e;
PDBTitle: fusion construct of cr17 from lrp-1 and apoe residues 130-149
72d1bpoa1
not modelled 10.9 29 Fold:alpha-alpha superhelix
Superfamily:ARM repeat
Family:Clathrin heavy-chain linker domain
73c2fylB_
not modelled 10.9 23 PDB header:surface active protein
Chain: B: PDB Molecule:low-density lipoprotein receptor-related protein
PDBTitle: haddock model of the complex between double module of lrp,2 cr56, and first domain of receptor associated protein, rap-3 d1.
74c2fcwB_
not modelled 10.1 32 PDB header:lipid transport/endocytosis/chaperone
Chain: B: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: structure of a complex between the pair of the ldl receptor2 ligand-binding modules 3-4 and the receptor associated3 protein (rap).
75d1o66a_
not modelled 9.7 28 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Ketopantoate hydroxymethyltransferase PanB
76d1odha_
not modelled 9.6 37 Fold:GCM domain
Superfamily:GCM domain
Family:GCM domain
77c2iswB_
not modelled 9.5 9 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate
78d1dval1
not modelled 9.5 19 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:EGF/Laminin
Family:EGF-type module
79d1r75a_
not modelled 9.4 26 Fold:Smp-1-like
Superfamily:Smp-1-like
Family:Smp-1-like
80c2kvcA_
not modelled 9.2 23 PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: solution structure of the mycobacterium tuberculosis protein rv0543c,2 a member of the duf3349 superfamily. seattle structural genomics3 center for infectious disease target mytud.17112.a
81d1k7ba_
not modelled 9.1 24 Fold:LDL receptor-like module
Superfamily:LDL receptor-like module
Family:LDL receptor-like module
82c3gt2A_
not modelled 9.1 13 PDB header:unknown function
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the p60 domain from m. avium2 paratuberculosis antigen map1272c
83c3i86A_
not modelled 9.1 21 PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of the p60 domain from m. avium subspecies2 paratuberculosis antigen map1204
84d1k4ta3
not modelled 9.0 17 Fold:Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
Superfamily:Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
Family:Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment
85c2rpbA_
not modelled 8.9 6 PDB header:membrane protein
Chain: A: PDB Molecule:hypothetical membrane protein;
PDBTitle: the solution structure of membrane protein
86d3by5a1
not modelled 8.8 12 Fold:CobE/GbiG C-terminal domain-like
Superfamily:CobE/GbiG C-terminal domain-like
Family:CobE/GbiG C-terminal domain-like
87c3by5A_
not modelled 8.8 12 PDB header:biosynthetic protein
Chain: A: PDB Molecule:cobalamin biosynthesis protein;
PDBTitle: crystal structure of cobalamin biosynthesis protein chig from2 agrobacterium tumefaciens str. c58
88c3si5X_
not modelled 8.8 38 PDB header:cell cycle
Chain: X: PDB Molecule:protein casc5;
PDBTitle: kinetochore-bubr1 kinase complex
89d1ay7b_
not modelled 8.7 13 Fold:Barstar-like
Superfamily:Barstar-related
Family:Barstar-related
90c2knxA_
not modelled 8.2 32 PDB header:protein binding
Chain: A: PDB Molecule:prolow-density lipoprotein receptor-related protein 1;
PDBTitle: solution structure of complement repeat cr17 from lrp-1
91c2ojlB_
not modelled 8.2 27 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of q7waf1_borpa from bordetella parapertussis.2 northeast structural genomics target bpr68.
92c3n2bD_
not modelled 7.5 17 PDB header:lyase
Chain: D: PDB Molecule:diaminopimelate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of diaminopimelate2 decarboxylase (lysa) from vibrio cholerae.
93c2ri0B_
not modelled 7.5 10 PDB header:hydrolase
Chain: B: PDB Molecule:glucosamine-6-phosphate deaminase;
PDBTitle: crystal structure of glucosamine 6-phosphate deaminase (nagb) from s.2 mutans
94c2xr9A_
not modelled 7.4 31 PDB header:hydrolase
Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family
PDBTitle: crystal structure of autotaxin (enpp2)
95d2v9va1
not modelled 7.4 71 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:C-terminal fragment of elongation factor SelB
96c2npbA_
not modelled 7.3 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:selenoprotein w;
PDBTitle: nmr solution structure of mouse selw
97d2j8ba1
not modelled 7.2 18 Fold:Snake toxin-like
Superfamily:Snake toxin-like
Family:Extracellular domain of cell surface receptors
98c1y89B_
not modelled 7.1 38 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:devb protein;
PDBTitle: crystal structure of devb protein
99c2p0gB_
not modelled 7.1 30 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:selenoprotein w-related protein;
PDBTitle: crystal structure of selenoprotein w-related protein from2 vibrio cholerae. northeast structural genomics target vcr75

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0