Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	E	L	N	A	K	T	T	A	L	V	V	I	D	L	Q	E	G	I	L	P	F	A	G	G	P	H	T	A	D	E	V	V	N	R	A	G	K	L	A	A	K	F	R	A	S	G	Q	P	V	F	L	V	R	V	G	W	S	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	Y	A	E	A	L	K	Q	P	V	D	A	P	S	P	A	K	V	L	P	E	N	W	W	Q	H	P	A	A	L	G	A	T	D	S	D	I	E	I	I	K	R	Q	W	G	A	F	Y	G	T	D	L	E	L	Q	L	R	R	R	G
Secondary structure
SS confidence
Disorder			?	?		?			?	?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	D	T	I	V	L	C	G	I	S	T	N	I	G	V	E	S	T	A	R	N	A	W	E	L	G	F	N	L	V	I	A	E	D	A	C	S	A	A	S	A	E	Q	H	N	N	S	I	N	H	I	Y	P	R	I	A	R	V	R	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.
Sequence		V	E	E	I	L	N	A	L
Secondary structure
SS confidence
Disorder								?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1j2r chain A Region: 1 - 188 Aligned: 188 Modelled: 188 Confidence: 100.0% Identity: 99% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 1nba chain A Region: 7 - 188 Aligned: 182 Modelled: 182 Confidence: 100.0% Identity: 21% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 2fq1 chain A Region: 4 - 187 Aligned: 183 Modelled: 184 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains Phyre2 PDB 3irv chain A Region: 2 - 188 Aligned: 187 Modelled: 187 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 3kl2 chain K Region: 3 - 188 Aligned: 186 Modelled: 186 Confidence: 100.0% Identity: 30% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 PDB 1nf9 chain A Region: 2 - 186 Aligned: 183 Modelled: 185 Confidence: 100.0% Identity: 21% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3mcw chain A Region: 2 - 188 Aligned: 175 Modelled: 175 Confidence: 100.0% Identity: 30% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution Phyre2 PDB 3hu5 chain B Region: 7 - 188 Aligned: 182 Modelled: 182 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough Phyre2 PDB 3ot4 chain F Region: 6 - 186 Aligned: 180 Modelled: 181 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf Phyre2 PDB 3hb7 chain G Region: 7 - 188 Aligned: 179 Modelled: 182 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a Phyre2 PDB 3oqp chain A Region: 8 - 188 Aligned: 168 Modelled: 169 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3oqp chain B Region: 8 - 188 Aligned: 168 Modelled: 169 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3eef chain A Region: 7 - 186 Aligned: 173 Modelled: 179 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 3r2j chain C Region: 2 - 187 Aligned: 183 Modelled: 186 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate Phyre2 PDB 2wta chain A Region: 2 - 187 Aligned: 182 Modelled: 186 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease Phyre2 PDB 1im5 chain A Region: 8 - 179 Aligned: 171 Modelled: 172 Confidence: 100.0% Identity: 22% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3o93 chain A Region: 8 - 188 Aligned: 179 Modelled: 181 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes Phyre2 PDB 3lqy chain A Region: 3 - 186 Aligned: 170 Modelled: 171 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica Phyre2 PDB 1yac chain A Region: 2 - 188 Aligned: 165 Modelled: 166 Confidence: 100.0% Identity: 18% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3gbc chain A Region: 10 - 181 Aligned: 172 Modelled: 172 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide Phyre2 1 d1j2ra_ 2 d1nbaa_ 3 c2fq1A_ 4 c3irvA_ 5 c3kl2K_ 6 d1nf9a_ 7 c3mcwA_ 8 c3hu5B_ 9 c3ot4F_ 10 c3hb7G_ 11 c3oqpA_ 12 c3oqpB_ 13 c3eefA_ 14 c3r2jC_ 15 c2wtaA_ 16 d1im5a_ 17 c3o93A_ 18 c3lqyA_ 19 d1yaca_ 20 c3gbcA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1j2ra_ 100.0 99 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 2 d1nbaa_ 100.0 21 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 3 c2fq1A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 4 c3irvA_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 5 c3kl2K_ 100.0 30 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 6 d1nf9a_ 100.0 21 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 7 c3mcwA_ 100.0 30 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 8 c3hu5B_ 100.0 27 PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough 9 c3ot4F_ 100.0 21 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 10 c3hb7G_ 100.0 21 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 11 c3oqpA_ 100.0 29 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 12 c3oqpB_ 100.0 29 PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 13 c3eefA_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 14 c3r2jC_ 100.0 16 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate 15 c2wtaA_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease 16 d1im5a_ 100.0 22 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 17 c3o93A_ 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes 18 c3lqyA_ 100.0 28 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica 19 d1yaca_ 100.0 18 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 20 c3gbcA_ 100.0 17 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 21 c2a67C_ not modelled 100.0 24 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein 22 c1yzvA_ not modelled 100.0 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: hypothetical protein from trypanosoma cruzi 23 c2b34C_ not modelled 100.0 19 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 24 d1x9ga_ not modelled 100.0 17 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 25 c2h0rD_ not modelled 100.0 20 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 26 d1cmwa2 not modelled 85.4 16 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 27 c1x1qA_ not modelled 80.8 17 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase beta chain; PDBTitle: crystal structure of tryptophan synthase beta chain from thermus2 thermophilus hb8 28 d1tfra2 not modelled 66.9 5 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 29 c2ihnA_ not modelled 66.7 7 PDB header:hydrolase/dna Chain: A: PDB Molecule:ribonuclease h; PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate 30 c1ortD_ not modelled 65.1 12 PDB header:transferase Chain: D: PDB Molecule:ornithine transcarbamoylase; PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa 31 d1xdpa3 not modelled 65.0 9 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 32 d1a9xa3 not modelled 61.6 18 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 33 c3bh0A_ not modelled 60.7 15 PDB header:replication Chain: A: PDB Molecule:dnab-like replicative helicase; PDBTitle: atpase domain of g40p 34 d1qopb_ not modelled 57.8 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 35 c1cmwA_ not modelled 54.1 17 PDB header:transferase Chain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain 36 d1vp8a_ not modelled 48.2 19 Fold:Pyruvate kinase C-terminal domain-like Superfamily:PK C-terminal domain-like Family:MTH1675-like 37 c2w37A_ not modelled 47.6 10 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 38 c1xdoB_ not modelled 47.6 9 PDB header:transferase Chain: B: PDB Molecule:polyphosphate kinase; PDBTitle: crystal structure of escherichia coli polyphosphate kinase 39 c1f8sA_ not modelled 45.6 28 PDB header:oxidoreductase Chain: A: PDB Molecule:l-amino acid oxidase; PDBTitle: crystal structure of l-amino acid oxidase from calloselasma2 rhodostoma, complexed with three molecules of o-aminobenzoate. 40 c3bgwD_ not modelled 43.4 15 PDB header:replication Chain: D: PDB Molecule:dnab-like replicative helicase; PDBTitle: the structure of a dnab-like replicative helicase and its interactions2 with primase 41 c1vlvA_ not modelled 43.0 12 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution 42 d1szpa2 not modelled 42.1 11 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 43 c1xp8A_ not modelled 40.0 17 PDB header:dna binding protein Chain: A: PDB Molecule:reca protein; PDBTitle: "deinococcus radiodurans reca in complex with atp-gamma-s" 44 d2ae2a_ not modelled 39.1 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 45 d1pv8a_ not modelled 36.0 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 46 c2rgoA_ not modelled 35.3 21 PDB header:oxidoreductase Chain: A: PDB Molecule:alpha-glycerophosphate oxidase; PDBTitle: structure of alpha-glycerophosphate oxidase from2 streptococcus sp.: a template for the mitochondrial alpha-3 glycerophosphate dehydrogenase 47 c3cbwA_ not modelled 34.4 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ydht protein; PDBTitle: crystal structure of the ydht protein from bacillus subtilis 48 c3nugA_ not modelled 32.4 21 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase; PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti 49 c1ipaA_ not modelled 31.8 18 PDB header:transferase Chain: A: PDB Molecule:rna 2'-o-ribose methyltransferase; PDBTitle: crystal structure of rna 2'-o ribose methyltransferase 50 d1xp8a1 not modelled 30.2 19 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 51 c2dflA_ not modelled 29.9 10 PDB header:recombination Chain: A: PDB Molecule:dna repair and recombination protein rada; PDBTitle: crystal structure of left-handed rada filament 52 d2iida1 not modelled 29.0 24 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 53 c1t4gA_ not modelled 28.5 13 PDB header:recombination Chain: A: PDB Molecule:dna repair and recombination protein rada; PDBTitle: atpase in complex with amp-pnp 54 d1duvg2 not modelled 28.1 15 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 55 d1ae1a_ not modelled 28.0 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 56 d1dxha2 not modelled 27.2 17 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 57 d1xsea_ not modelled 26.9 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 58 c1z2iA_ not modelled 26.9 16 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium 59 d1xu9a_ not modelled 26.5 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 60 c3o26A_ not modelled 26.2 14 PDB header:oxidoreductase Chain: A: PDB Molecule:salutaridine reductase; PDBTitle: the structure of salutaridine reductase from papaver somniferum. 61 c2ha8A_ not modelled 25.8 9 PDB header:rna binding protein Chain: A: PDB Molecule:tar (hiv-1) rna loop binding protein; PDBTitle: methyltransferase domain of human tar (hiv-1) rna binding2 protein 1 62 c3nklA_ not modelled 25.8 13 PDB header:oxidoreductase/lyase Chain: A: PDB Molecule:udp-d-quinovosamine 4-dehydrogenase; PDBTitle: crystal structure of udp-d-quinovosamine 4-dehydrogenase from vibrio2 fischeri 63 c2vyeA_ not modelled 25.4 22 PDB header:hydrolase Chain: A: PDB Molecule:replicative dna helicase; PDBTitle: crystal structure of the dnac-ssdna complex 64 d1tyza_ not modelled 25.4 22 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 65 d1f2da_ not modelled 25.3 18 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 66 d1v8za1 not modelled 25.0 16 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 67 c2y8kA_ not modelled 24.8 13 PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate binding family 6; PDBTitle: structure of ctgh5-cbm6, an arabinoxylan-specific xylanase. 68 c3g68A_ not modelled 24.7 18 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerase; PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution 69 c3ldaA_ not modelled 24.7 12 PDB header:dna binding protein Chain: A: PDB Molecule:dna repair protein rad51; PDBTitle: yeast rad51 h352y filament interface mutant 70 c3euaD_ not modelled 24.5 9 PDB header:isomerase Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase; PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution 71 c3fkjA_ not modelled 24.4 7 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerases; PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution 72 c2recB_ not modelled 24.3 17 PDB header:helicase PDB COMPND: 73 d1ooea_ not modelled 24.3 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 74 c3ijrF_ not modelled 24.2 20 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+ 75 c2nm0B_ not modelled 24.0 23 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2) 76 c3updA_ not modelled 23.9 11 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus 77 c3uoeB_ not modelled 23.8 10 PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti 78 d1qsga_ not modelled 23.4 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 79 c3toxG_ not modelled 23.1 19 PDB header:oxidoreductase Chain: G: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021 80 c2b4qB_ not modelled 22.8 25 PDB header:oxidoreductase Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl- PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex 81 d1xrha_ not modelled 22.6 8 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 82 d1c0pa1 not modelled 22.4 21 Fold:Nucleotide-binding domain Superfamily:Nucleotide-binding domain Family:D-aminoacid oxidase, N-terminal domain 83 d1onfa2 not modelled 21.5 12 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD/NAD-linked reductases, N-terminal and central domains 84 c2rghA_ not modelled 21.1 21 PDB header:oxidoreductase Chain: A: PDB Molecule:alpha-glycerophosphate oxidase; PDBTitle: structure of alpha-glycerophosphate oxidase from2 streptococcus sp.: a template for the mitochondrial alpha-3 glycerophosphate dehydrogenase 85 d2o8ra3 not modelled 21.0 11 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:Polyphosphate kinase C-terminal domain 86 d1reoa1 not modelled 20.9 26 Fold:FAD/NAD(P)-binding domain Superfamily:FAD/NAD(P)-binding domain Family:FAD-linked reductases, N-terminal domain 87 c2e4gB_ not modelled 20.4 15 PDB header:biosynthetic protein, flavoprotein Chain: B: PDB Molecule:tryptophan halogenase; PDBTitle: rebh with bound l-trp 88 d1xg5a_ not modelled 20.3 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 89 d1xq1a_ not modelled 20.0 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 90 d2i1qa2 not modelled 19.8 13 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 91 c2v1dA_ not modelled 19.5 32 PDB header:oxidoreductase/repressor Chain: A: PDB Molecule:lysine-specific histone demethylase 1; PDBTitle: structural basis of lsd1-corest selectivity in histone h32 recognition 92 c2xagA_ not modelled 19.5 32 PDB header:transcription Chain: A: PDB Molecule:lysine-specific histone demethylase 1; PDBTitle: crystal structure of lsd1-corest in complex with para-bromo-2 (-)-trans-2-phenylcyclopropyl-1-amine 93 d1nxua_ not modelled 19.1 12 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 94 d1a9xa4 not modelled 19.1 18 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 95 d1iz5a1 not modelled 18.9 18 Fold:DNA clamp Superfamily:DNA clamp Family:DNA polymerase processivity factor 96 d1rfma_ not modelled 18.5 20 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 97 c2weuD_ not modelled 18.3 14 PDB header:antifungal protein Chain: D: PDB Molecule:tryptophan 5-halogenase; PDBTitle: crystal structure of tryptophan 5-halogenase (pyrh) complex2 with substrate tryptophan 98 d1plqa1 not modelled 17.9 9 Fold:DNA clamp Superfamily:DNA clamp Family:DNA polymerase processivity factor 99 d2c07a1 not modelled 17.5 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0