Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	Q	A	L	K	N	L	L	T	L	L	N	L	E	K	I	E	E	G	L	F	R	G	Q	S	E	D	L	G	L	R	Q	V	F	G	G	Q	V	V	G	Q	A	L	Y	A	A	K	E	T	V	P	E	E	R	L	V	H	S	F
Secondary structure
SS confidence
Disorder		?	?	?	?																									?	?																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	S	Y	F	L	R	P	G	D	S	K	K	P	I	I	Y	D	V	E	T	L	R	D	G	N	S	F	S	A	R	R	V	A	A	I	Q	N	G	K	P	I	F	Y	M	T	A	S	F	Q	A	P	E	A	G	F	E	H	Q	K	T
Secondary structure
SS confidence
Disorder																																																						?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		M	P	S	A	P	A	P	D	G	L	P	S	E	T	Q	I	A	Q	S	L	A	H	L	L	P	P	V	L	K	D	K	F	I	C	D	R	P	L	E	V	R	P	V	E	F	H	N	P	L	K	G	H	V	A	E	P	H	R	Q	V
Secondary structure
SS confidence
Disorder																																?																?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		W	I	R	A	N	G	S	V	P	D	D	L	R	V	H	Q	Y	L	L	G	Y	A	S	D	L	N	F	L	P	V	A	L	Q	P	H	G	I	G	F	L	E	P	G	I	Q	I	A	T	I	D	H	S	M	W	F	H	R	P	F	N
Secondary structure
SS confidence
Disorder																																				?		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.
Sequence		L	N	E	W	L	L	Y	S	V	E	S	T	S	A	S	S	A	R	G	F	V	R	G	E	F	Y	T	Q	D	G	V	L	V	A	S	T	V	Q	E	G	V	M	R	N	H	N
Secondary structure
SS confidence
Disorder																																									?	?			?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1c8u chain A Region: 2 - 286 Aligned: 285 Modelled: 285 Confidence: 100.0% Identity: 100% PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase ii; PDBTitle: crystal structure of the e.coli thioesterase ii, a2 homologue of the human nef-binding enzyme Phyre2 PDB 3rd7 chain A Region: 1 - 283 Aligned: 271 Modelled: 273 Confidence: 100.0% Identity: 35% PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase; PDBTitle: crystal structure of acyl-coa thioesterase from mycobacterium avium Phyre2 PDB 3rqb chain B Region: 1 - 283 Aligned: 253 Modelled: 258 Confidence: 100.0% Identity: 22% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of conserved protein of unknown function with hot2 dog fold from alicyclobacillus acidocaldarius Phyre2 PDB 3bbj chain A Region: 6 - 283 Aligned: 259 Modelled: 269 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase ii; PDBTitle: crystal structure of a putative thioesterase ii (tfu_2367) from2 thermobifida fusca yx at 2.45 a resolution Phyre2 PDB 3cjy chain A Region: 10 - 283 Aligned: 245 Modelled: 267 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of putative thioesterase (yp_496845.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.70 a resolution Phyre2 PDB 1c8u chain A domain 2 Region: 116 - 286 Aligned: 171 Modelled: 171 Confidence: 100.0% Identity: 100% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: Acyl-CoA thioesterase Phyre2 PDB 1c8u chain A domain 1 Region: 2 - 115 Aligned: 114 Modelled: 114 Confidence: 100.0% Identity: 100% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: Acyl-CoA thioesterase Phyre2 PDB 1tbu chain A domain 1 Region: 10 - 110 Aligned: 96 Modelled: 101 Confidence: 100.0% Identity: 35% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: Acyl-CoA thioesterase Phyre2 PDB 3b7k chain A Region: 25 - 277 Aligned: 223 Modelled: 235 Confidence: 99.2% Identity: 11% PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 12; PDBTitle: human acyl-coenzyme a thioesterase 12 Phyre2 PDB 2gvh chain C Region: 32 - 277 Aligned: 196 Modelled: 200 Confidence: 99.1% Identity: 13% PDB header:hydrolase Chain: C: PDB Molecule:agr_l_2016p; PDBTitle: crystal structure of acyl-coa hydrolase (15159470) from agrobacterium2 tumefaciens at 2.65 a resolution Phyre2 PDB 2pim chain A Region: 2 - 110 Aligned: 108 Modelled: 109 Confidence: 99.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution Phyre2 PDB 1wlu chain A domain 1 Region: 4 - 110 Aligned: 106 Modelled: 107 Confidence: 99.0% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2qwz chain B Region: 12 - 111 Aligned: 100 Modelled: 100 Confidence: 99.0% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution Phyre2 PDB 1zki chain A domain 1 Region: 3 - 110 Aligned: 106 Modelled: 108 Confidence: 98.9% Identity: 11% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2h4u chain A domain 1 Region: 5 - 108 Aligned: 104 Modelled: 104 Confidence: 98.8% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2hbo chain A domain 1 Region: 2 - 110 Aligned: 109 Modelled: 109 Confidence: 98.8% Identity: 16% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2f0x chain A domain 1 Region: 2 - 108 Aligned: 107 Modelled: 107 Confidence: 98.8% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 3lbe chain A Region: 12 - 108 Aligned: 97 Modelled: 97 Confidence: 98.7% Identity: 13% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein smu.793; PDBTitle: the crystal structure of smu.793 from streptococcus mutans ua159 bound2 to acetyl coa Phyre2 PDB 3f1t chain B Region: 12 - 111 Aligned: 100 Modelled: 97 Confidence: 98.7% Identity: 20% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein q9i3c8_pseae; PDBTitle: crystal structure of the q9i3c8_pseae protein from pseudomonas2 aeruginosa. northeast structural genomics consortium target par319a. Phyre2 PDB 2fs2 chain A domain 1 Region: 4 - 110 Aligned: 106 Modelled: 107 Confidence: 98.7% Identity: 17% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 1 c1c8uA_ 2 c3rd7A_ 3 c3rqbB_ 4 c3bbjA_ 5 c3cjyA_ 6 d1c8ua2 7 d1c8ua1 8 d1tbua1 9 c3b7kA_ 10 c2gvhC_ 11 c2pimA_ 12 d1wlua1 13 c2qwzB_ 14 d1zkia1 15 d2h4ua1 16 d2hboa1 17 d2f0xa1 18 c3lbeA_ 19 c3f1tB_ 20 d2fs2a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1c8uA_ 100.0 100 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase ii; PDBTitle: crystal structure of the e.coli thioesterase ii, a2 homologue of the human nef-binding enzyme 2 c3rd7A_ 100.0 35 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase; PDBTitle: crystal structure of acyl-coa thioesterase from mycobacterium avium 3 c3rqbB_ 100.0 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of conserved protein of unknown function with hot2 dog fold from alicyclobacillus acidocaldarius 4 c3bbjA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase ii; PDBTitle: crystal structure of a putative thioesterase ii (tfu_2367) from2 thermobifida fusca yx at 2.45 a resolution 5 c3cjyA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of putative thioesterase (yp_496845.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.70 a resolution 6 d1c8ua2 100.0 100 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 7 d1c8ua1 100.0 100 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 8 d1tbua1 100.0 35 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 9 c3b7kA_ 99.2 11 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 12; PDBTitle: human acyl-coenzyme a thioesterase 12 10 c2gvhC_ 99.1 13 PDB header:hydrolase Chain: C: PDB Molecule:agr_l_2016p; PDBTitle: crystal structure of acyl-coa hydrolase (15159470) from agrobacterium2 tumefaciens at 2.65 a resolution 11 c2pimA_ 99.0 19 PDB header:hydrolase Chain: A: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution 12 d1wlua1 99.0 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 13 c2qwzB_ 99.0 14 PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution 14 d1zkia1 98.9 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 15 d2h4ua1 98.8 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 16 d2hboa1 98.8 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 17 d2f0xa1 98.8 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 18 c3lbeA_ 98.7 13 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein smu.793; PDBTitle: the crystal structure of smu.793 from streptococcus mutans ua159 bound2 to acetyl coa 19 c3f1tB_ 98.7 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein q9i3c8_pseae; PDBTitle: crystal structure of the q9i3c8_pseae protein from pseudomonas2 aeruginosa. northeast structural genomics consortium target par319a. 20 d2fs2a1 98.7 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 21 d1ixla_ not modelled 98.7 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 22 c3lwgB_ not modelled 98.7 20 PDB header:unknown function Chain: B: PDB Molecule:hp0420 homologue; PDBTitle: crystal structure of hp0420-homologue c46a from helicobacter2 felis 23 c3e29C_ not modelled 98.6 14 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein q7we92_borbr; PDBTitle: x-ray structure of the protein q7we92_borbr from thioesterase2 superfamily. northeast structural genomics consortium target bor214a. 24 c3e8pA_ not modelled 98.5 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the protein q8e9m7 from shewanella2 oneidensis related to thioesterase superfamily. northeast3 structural genomics consortium target sor246. 25 d2cy9a1 not modelled 98.5 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 26 c3s4kA_ not modelled 98.5 17 PDB header:hydrolase Chain: A: PDB Molecule:putative esterase rv1847/mt1895; PDBTitle: structure of a putative esterase rv1847/mt1895 from mycobacterium2 tuberculosis 27 d1q4ua_ not modelled 98.5 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 28 c3nwzD_ not modelled 98.5 16 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:bh2602 protein; PDBTitle: crystal structure of bh2602 protein from bacillus halodurans with coa,2 northeast structural genomics consortium target bhr199 29 d2ov9a1 not modelled 98.5 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 30 d1vh9a_ not modelled 98.5 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 31 c3gekA_ not modelled 98.5 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioesterase yhda; PDBTitle: crystal structure of putative thioesterase yhda from lactococcus2 lactis. northeast structural genomics consortium target kr113 32 c3dkzA_ not modelled 98.4 17 PDB header:hydrolase Chain: A: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of the q7w9w5_borpa protein from2 bordetella parapertussis. northeast structural genomics3 consortium target bpr208c. 33 d1vh5a_ not modelled 98.4 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 34 c3hduB_ not modelled 98.4 22 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (syn_01977) from2 syntrophus aciditrophicus sb at 2.50 a resolution 35 c2f3xA_ not modelled 98.4 13 PDB header:gene regulation Chain: A: PDB Molecule:transcription factor fapr; PDBTitle: crystal structure of fapr (in complex with effector)- a2 global regulator of fatty acid biosynthesis in b. subtilis 36 c3e1eE_ not modelled 98.3 22 PDB header:hydrolase Chain: E: PDB Molecule:thioesterase family protein; PDBTitle: crystal structure of a thioesterase family protein from2 silicibacter pomeroyi. northeast structural genomics3 target sir180a 37 c2eisA_ not modelled 98.3 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tthb207; PDBTitle: x-ray structure of acyl-coa hydrolase-like protein, tt1379, from2 thermus thermophilus hb8 38 d2f41a1 not modelled 98.3 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 39 d1vpma_ not modelled 98.2 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 40 c3bnvD_ not modelled 98.2 13 PDB header:unknown function Chain: D: PDB Molecule:cj0977; PDBTitle: crystal structure of cj0977, a sigma28-regulated virulence protein2 from campylobacter jejuni. 41 c2v1oF_ not modelled 98.2 11 PDB header:hydrolase Chain: F: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of n-terminal domain of acyl-coa2 thioesterase 7 42 d2gvha1 not modelled 98.2 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 43 d1t82a_ not modelled 98.2 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 44 c2qq2C_ not modelled 98.2 12 PDB header:hydrolase Chain: C: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of c-terminal domain of human acyl-coa thioesterase2 7 45 d1ylia1 not modelled 98.2 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 46 d1sc0a_ not modelled 98.1 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 47 d1sh8a_ not modelled 98.1 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 48 d2gvha2 not modelled 98.1 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 49 c3d6lA_ not modelled 98.1 19 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of cj0915, a hexameric hotdog fold2 thioesterase of campylobacter jejuni 50 c2prxB_ not modelled 98.0 12 PDB header:hydrolase Chain: B: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of thioesterase superfamily protein (zp_00837258.1)2 from shewanella loihica pv-4 at 1.65 a resolution 51 d1y7ua1 not modelled 98.0 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 52 d1yoca1 not modelled 97.9 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 53 c3ir3B_ not modelled 97.8 19 PDB header:lyase Chain: B: PDB Molecule:3-hydroxyacyl-thioester dehydratase 2; PDBTitle: crystal structure of human 3-hydroxyacyl-thioester dehydratase 22 (htd2) 54 d1iq6a_ not modelled 97.1 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 55 c3lmbA_ not modelled 97.0 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein olei01261 with unknown function2 from chlorobaculum tepidum tls 56 d2b3na1 not modelled 96.8 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 57 c2ownA_ not modelled 96.7 9 PDB header:hydrolase Chain: A: PDB Molecule:putative oleoyl-[acyl-carrier protein] thioesterase; PDBTitle: crystal structure of oleoyl thioesterase (putative) (np_784467.1) from2 lactobacillus plantarum at 2.00 a resolution 58 d1u1za_ not modelled 96.7 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 59 d2bi0a1 not modelled 96.7 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 60 d2hx5a1 not modelled 96.5 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 61 c3d6xA_ not modelled 96.4 9 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; PDBTitle: crystal structure of campylobacter jejuni fabz 62 c3kh8B_ not modelled 96.1 13 PDB header:lyase Chain: B: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of maoc-like dehydratase from phytophthora capsici 63 c2glvA_ not modelled 96.1 14 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-acyl carrier protein PDBTitle: crystal structure of (3r)-hydroxyacyl-acyl carrier protein2 dehydratase(fabz) mutant(y100a) from helicobacter pylori 64 d2oafa1 not modelled 95.9 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 65 d2gf6a1 not modelled 95.8 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 66 d2cyea1 not modelled 95.7 19 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 67 d2owna2 not modelled 95.4 6 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 68 d2oiwa1 not modelled 95.3 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 69 c3hm0C_ not modelled 95.3 9 PDB header:hydrolase Chain: C: PDB Molecule:probable thioesterase; PDBTitle: crystal structure of probable thioesterase from bartonella2 henselae 70 d1q6wa_ not modelled 95.1 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 71 d2essa1 not modelled 95.0 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 72 d1pn2a2 not modelled 95.0 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 73 d2hlja1 not modelled 94.8 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 74 c2essA_ not modelled 94.8 8 PDB header:hydrolase Chain: A: PDB Molecule:acyl-acp thioesterase; PDBTitle: crystal structure of an acyl-acp thioesterase (np_810988.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.90 a resolution 75 d1s5ua_ not modelled 94.6 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 76 c2w3xE_ not modelled 94.4 10 PDB header:hydrolase Chain: E: PDB Molecule:cale7; PDBTitle: crystal structure of a bifunctional hotdog fold2 thioesterase in enediyne biosynthesis, cale7 77 c2aliA_ not modelled 94.2 6 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa2801; PDBTitle: structure of protein of unknown function pa2801 from pseudomonas2 aeruginosa, putative thioesterase 78 d2alia1 not modelled 94.2 6 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 79 d1z6ba1 not modelled 94.1 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 80 d2owna1 not modelled 93.9 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 81 d1pn2a1 not modelled 93.6 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 82 c2egiE_ not modelled 93.6 5 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:hypothetical protein aq_1494; PDBTitle: crystal structure of a hypothetical protein(aq1494) from aquifex2 aeolicus 83 d1s9ca1 not modelled 93.6 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 84 c2cdhT_ not modelled 93.3 9 PDB header:transferase Chain: T: PDB Molecule:dehydratase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 85 d1njka_ not modelled 93.1 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 86 d1s9ca2 not modelled 93.0 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 87 c3kg9A_ not modelled 92.7 9 PDB header:lyase Chain: A: PDB Molecule:curk; PDBTitle: dehydratase domain from curk module of curacin polyketide synthase 88 c3exzA_ not modelled 92.5 9 PDB header:lyase Chain: A: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of the maoc-like dehydratase from rhodospirillum2 rubrum. northeast structural genomics consortium target rrr103a. 89 d2essa2 not modelled 92.4 5 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 90 d2o5ua1 not modelled 92.1 5 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 91 c2uvaI_ not modelled 92.0 9 PDB header:transferase Chain: I: PDB Molecule:fatty acid synthase beta subunits; PDBTitle: crystal structure of fatty acid synthase from thermomyces2 lanuginosus at 3.1 angstrom resolution. this file contains3 the beta subunits of the fatty acid synthase. the entire4 crystal structure consists of one heterododecameric fatty5 acid synthase and is described in remark 400 92 d1z54a1 not modelled 91.8 11 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 93 d1lo7a_ not modelled 91.2 5 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 94 c2bi0A_ not modelled 90.4 10 PDB header:hypothetical protein Chain: A: PDB Molecule:hypothetical protein rv0216; PDBTitle: rv0216, a conserved hypothetical protein from mycobacterium2 tuberculosis that is essential for bacterial survival3 during infection, has a double hotdogfold 95 c3khpB_ not modelled 88.7 12 PDB header:oxidoreductase Chain: B: PDB Molecule:maoc family protein; PDBTitle: crystal structure of a possible dehydrogenase from2 mycobacterium tuberculosis at 2.3a resolution 96 c3ck1B_ not modelled 88.4 16 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (reut_a2179) from2 ralstonia eutropha jmp134 at 1.74 a resolution 97 d2cwza1 not modelled 88.0 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:TTHA0967-like 98 c1s9cK_ not modelled 88.0 10 PDB header:lyase Chain: K: PDB Molecule:peroxisomal multifunctional enzyme type 2; PDBTitle: crystal structure analysis of the 2-enoyl-coa hydratase 22 domain of human peroxisomal multifunctional enzyme type 2 99 c2pzhC_ not modelled 87.4 11 PDB header:hydrolase Chain: C: PDB Molecule:hypothetical protein hp_0496; PDBTitle: ybgc thioesterase (hp0496) from helicobacter pylori 100 c1pn2D_ not modelled 86.0 10 PDB header:lyase Chain: D: PDB Molecule:peroxisomal hydratase-dehydrogenase-epimerase; PDBTitle: crystal structure analysis of the selenomethionine labelled2 2-enoyl-coa hydratase 2 domain of candida tropicalis3 multifunctional enzyme type 2 101 d1mkaa_ not modelled 85.8 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:beta-Hydroxydecanol thiol ester dehydrase 102 c2xflB_ not modelled 85.8 13 PDB header:hydrolase Chain: B: PDB Molecule:dyne7; PDBTitle: induced-fit and allosteric effects upon polyene binding2 revealed by crystal structures of the dynemicin3 thioesterase 103 c2vkzH_ not modelled 84.8 7 PDB header:transferase Chain: H: PDB Molecule:fatty acid synthase subunit beta; PDBTitle: structure of the cerulenin-inhibited fungal fatty acid2 synthase type i multienzyme complex 104 d2fuja1 not modelled 83.6 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 105 c3omlA_ not modelled 82.5 15 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415; PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster 106 d2bi0a2 not modelled 80.7 23 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 107 d2nuja1 not modelled 78.7 5 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 108 c3jzhA_ not modelled 73.0 3 PDB header:gene regulation Chain: A: PDB Molecule:polycomb protein eed; PDBTitle: eed-h3k79me3 109 d2c2ia1 not modelled 71.5 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 110 c3esiD_ not modelled 65.5 9 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from2 erwinia carotovora subsp. atroseptica. northeast3 structural genomics target ewr179 111 d1tbga_ not modelled 61.5 19 Fold:7-bladed beta-propeller Superfamily:WD40 repeat-like Family:WD40-repeat 112 c2pbiB_ not modelled 61.1 19 PDB header:signaling protein Chain: B: PDB Molecule:guanine nucleotide-binding protein subunit beta 5; PDBTitle: the multifunctional nature of gbeta5/rgs9 revealed from its crystal2 structure 113 c1nr0A_ not modelled 56.2 19 PDB header:structural protein Chain: A: PDB Molecule:actin interacting protein 1; PDBTitle: two seven-bladed beta-propeller domains revealed by the2 structure of a c. elegans homologue of yeast actin3 interacting protein 1 (aip1). 114 c2pm9A_ not modelled 54.6 8 PDB header:protein transport Chain: A: PDB Molecule:protein transport protein sec31; PDBTitle: crystal structure of yeast sec13/31 vertex element of the2 copii vesicular coat 115 c3kg7C_ not modelled 53.2 9 PDB header:lyase Chain: C: PDB Molecule:curh; PDBTitle: dehydratase domain from curh module of curacin polyketide synthase 116 c3eweC_ not modelled 48.7 19 PDB header:protein transport,structural protein Chain: C: PDB Molecule:nucleoporin seh1; PDBTitle: crystal structure of the nup85/seh1 complex 117 c3qooA_ not modelled 47.0 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of hot-dog-like taci_0573 protein from2 thermanaerovibrio acidaminovorans 118 c2qxvA_ not modelled 46.4 8 PDB header:gene regulation Chain: A: PDB Molecule:embryonic ectoderm development; PDBTitle: structural basis of ezh2 recognition by eed 119 c3iz6a_ not modelled 46.3 19 PDB header:ribosome Chain: A: PDB Molecule:40s ribosomal protein sa (s2p); PDBTitle: localization of the small subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome 120 c3kg8A_ not modelled 46.1 12 PDB header:lyase Chain: A: PDB Molecule:curj; PDBTitle: dehydratase domain from curj module of curacin polyketide synthase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0