Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	N	K	G	S	G	L	T	P	A	Q	A	L	D	K	L	D	A	L	Y	E	Q	S	V	V	A	L	R	N	A	I	G	N	Y	I	T	S	G	E	L	P	D	E	N	A	R	K	Q	G	L	F	V	Y	P	S	L	T	V	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?																												?			?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		W	D	G	S	T	T	N	P	P	K	T	R	A	F	G	R	F	T	H	A	G	S	Y	T	T	T	I	T	R	P	T	L	F	R	S	Y	L	N	E	Q	L	T	L	L	Y	Q	D	Y	G	A	H	I	S	V	Q	P	S	Q	H	E
Secondary structure
SS confidence
Disorder			?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	P	Y	P	Y	V	I	D	G	S	E	L	T	L	D	R	S	M	S	A	G	L	T	R	Y	F	P	T	T	E	L	A	Q	I	G	D	E	T	A	D	G	I	Y	H	P	T	E	F	S	P	L	S	H	F	D	A	R	R	V	D
Secondary structure
SS confidence
Disorder									?			?	?	?	?	?	?	?	?	?	?	?	?	?	?																												?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	S	L	A	R	L	R	H	Y	T	G	T	P	V	E	H	F	Q	P	F	V	L	F	T	N	Y	T	R	Y	V	D	E	F	V	R	W	G	C	S	Q	I	L	D	P	D	S	P	Y	I	A	L	S	C	A	G	G	N	W	I	T
Secondary structure
SS confidence
Disorder																																							?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	E	T	E	A	P	E	E	A	I	S	D	L	A	W	K	K	H	Q	M	P	A	W	H	L	I	T	A	D	G	Q	G	I	T	L	V	N	I	G	V	G	P	S	N	A	K	T	I	C	D	H	L	A	V	L	R	P	D	V	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	M	I	G	H	C	G	G	L	R	E	S	Q	A	I	G	D	Y	V	L	A	H	A	Y	L	R	D	D	H	V	L	D	A	V	L	P	P	D	I	P	I	P	S	I	A	E	V	Q	R	A	L	Y	D	A	T	K	L	V	S	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		R	P	G	E	E	V	K	Q	R	L	R	T	G	T	V	V	T	T	D	D	R	N	W	E	L	R	Y	S	A	S	A	L	R	F	N	L	S	R	A	V	A	I	D	M	E	S	A	T	I	A	A	Q	G	Y	R	F	R	V	P	Y
Secondary structure
SS confidence
Disorder		?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	T	L	L	C	V	S	D	K	P	L	H	G	E	I	K	L	P	G	Q	A	N	R	F	Y	E	G	A	I	S	E	H	L	Q	I	G	I	R	A	I	D	L	L	R	A	E	G	D	R	L	H	S	R	K	L	R	T	F	N	E
Secondary structure
SS confidence
Disorder																?	?	?	?	?																												?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.
Sequence		P	P	F	R
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1t8s chain A Region: 8 - 484 Aligned: 443 Modelled: 459 Confidence: 100.0% Identity: 99% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1ybf chain A Region: 178 - 466 Aligned: 238 Modelled: 251 Confidence: 100.0% Identity: 32% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3mb8 chain A Region: 190 - 466 Aligned: 236 Modelled: 249 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from toxoplasma2 gondii in complex with immucillin-h Phyre2 PDB 1nw4 chain C Region: 267 - 466 Aligned: 190 Modelled: 200 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase, putative; PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate Phyre2 PDB 1q1g chain A Region: 267 - 466 Aligned: 190 Modelled: 200 Confidence: 100.0% Identity: 22% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3qpb chain B Region: 267 - 469 Aligned: 190 Modelled: 203 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily Phyre2 PDB 1odk chain A Region: 267 - 463 Aligned: 177 Modelled: 197 Confidence: 100.0% Identity: 20% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3bje chain A Region: 267 - 460 Aligned: 191 Modelled: 194 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:nucleoside phosphorylase, putative; PDBTitle: crystal structure of trypanosoma brucei nucleoside phosphorylase shows2 uridine phosphorylase activity Phyre2 PDB 1k9s chain A Region: 267 - 463 Aligned: 183 Modelled: 197 Confidence: 100.0% Identity: 17% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1vhw chain A Region: 267 - 463 Aligned: 183 Modelled: 197 Confidence: 100.0% Identity: 16% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1rxy chain A Region: 267 - 463 Aligned: 185 Modelled: 197 Confidence: 100.0% Identity: 21% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 1z34 chain A Region: 267 - 463 Aligned: 178 Modelled: 197 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine Phyre2 PDB 2xrf chain A Region: 270 - 463 Aligned: 182 Modelled: 194 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:uridine phosphorylase 2; PDBTitle: crystal structure of human uridine phosphorylase 2 Phyre2 PDB 1je0 chain A Region: 267 - 460 Aligned: 173 Modelled: 194 Confidence: 100.0% Identity: 18% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3tl6 chain B Region: 184 - 459 Aligned: 216 Modelled: 229 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from entamoeba2 histolytica Phyre2 PDB 3euf chain C Region: 270 - 463 Aligned: 183 Modelled: 194 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase 1; PDBTitle: crystal structure of bau-bound human uridine phosphorylase 1 Phyre2 PDB 2ac7 chain A domain 1 Region: 267 - 459 Aligned: 168 Modelled: 178 Confidence: 100.0% Identity: 22% Fold: Phosphorylase/hydrolase-like Superfamily: Purine and uridine phosphorylases Family: Purine and uridine phosphorylases Phyre2 PDB 3bl6 chain A Region: 263 - 467 Aligned: 193 Modelled: 204 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a Phyre2 PDB 3eei chain A Region: 263 - 463 Aligned: 194 Modelled: 201 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:5-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of 5'-methylthioadenosine/s-2 adenosylhomocysteine nucleosidase from neisseria3 meningitidis in complex with methylthio-immucillin-a Phyre2 PDB 3dp9 chain A Region: 263 - 467 Aligned: 194 Modelled: 205 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:mta/sah nucleosidase; PDBTitle: crystal structure of vibrio cholerae 5'-methylthioadenosine/s-adenosyl2 homocysteine nucleosidase (mtan) complexed with butylthio-dadme-3 immucillin a Phyre2 1 d1t8sa_ 2 d1ybfa_ 3 c3mb8A_ 4 c1nw4C_ 5 d1q1ga_ 6 c3qpbB_ 7 d1odka_ 8 c3bjeA_ 9 d1k9sa_ 10 d1vhwa_ 11 d1rxya_ 12 c1z34A_ 13 c2xrfA_ 14 d1je0a_ 15 c3tl6B_ 16 c3eufC_ 17 d2ac7a1 18 c3bl6A_ 19 c3eeiA_ 20 c3dp9A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1t8sa_ 100.0 99 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 2 d1ybfa_ 100.0 32 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 3 c3mb8A_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from toxoplasma2 gondii in complex with immucillin-h 4 c1nw4C_ 100.0 22 PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase, putative; PDBTitle: crystal structure of plasmodium falciparum purine nucleoside2 phosphorylase in complex with immh and sulfate 5 d1q1ga_ 100.0 22 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 6 c3qpbB_ 100.0 22 PDB header:transferase Chain: B: PDB Molecule:uridine phosphorylase; PDBTitle: crystal structure of streptococcus pyogenes uridine phosphorylase2 reveals a subclass of the np-i superfamily 7 d1odka_ 100.0 20 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 8 c3bjeA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:nucleoside phosphorylase, putative; PDBTitle: crystal structure of trypanosoma brucei nucleoside phosphorylase shows2 uridine phosphorylase activity 9 d1k9sa_ 100.0 17 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 10 d1vhwa_ 100.0 16 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 11 d1rxya_ 100.0 21 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 12 c1z34A_ 100.0 22 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of trichomonas vaginalis purine nucleoside2 phosphorylase complexed with 2-fluoro-2'-deoxyadenosine 13 c2xrfA_ 100.0 16 PDB header:transferase Chain: A: PDB Molecule:uridine phosphorylase 2; PDBTitle: crystal structure of human uridine phosphorylase 2 14 d1je0a_ 100.0 18 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 15 c3tl6B_ 100.0 17 PDB header:transferase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of purine nucleoside phosphorylase from entamoeba2 histolytica 16 c3eufC_ 100.0 16 PDB header:transferase Chain: C: PDB Molecule:uridine phosphorylase 1; PDBTitle: crystal structure of bau-bound human uridine phosphorylase 1 17 d2ac7a1 100.0 22 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 18 c3bl6A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of staphylococcus aureus 5'-2 methylthioadenosine/s-adenosylhomocysteine nucleosidase in3 complex with formycin a 19 c3eeiA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:5-methylthioadenosine nucleosidase/s- PDBTitle: crystal structure of 5'-methylthioadenosine/s-2 adenosylhomocysteine nucleosidase from neisseria3 meningitidis in complex with methylthio-immucillin-a 20 c3dp9A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:mta/sah nucleosidase; PDBTitle: crystal structure of vibrio cholerae 5'-methylthioadenosine/s-adenosyl2 homocysteine nucleosidase (mtan) complexed with butylthio-dadme-3 immucillin a 21 c3nm5B_ not modelled 100.0 18 PDB header:hydrolase Chain: B: PDB Molecule:mta/sah nucleosidase; PDBTitle: helicobacter pylori mtan complexed with formycin a 22 c1zosE_ not modelled 100.0 20 PDB header:hydrolase Chain: E: PDB Molecule:5'-methylthioadenosine / s-adenosylhomocysteine PDBTitle: structure of 5'-methylthionadenosine/s-adenosylhomocysteine2 nucleosidase from s. pneumoniae with a transition-state3 inhibitor mt-imma 23 d1jysa_ not modelled 100.0 22 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 24 c2h8gA_ not modelled 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:5'-methylthioadenosine nucleosidase; PDBTitle: 5'-methylthioadenosine nucleosidase from arabidopsis2 thaliana 25 c3bsfB_ not modelled 100.0 19 PDB header:hydrolase Chain: B: PDB Molecule:at4g34840; PDBTitle: crystal structure of the mta/sah nucleosidase 26 c3ozbF_ not modelled 99.9 13 PDB header:transferase Chain: F: PDB Molecule:methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-methylthioinosine phosphorylase from2 psedomonas aeruginosa in complex with hypoxanthine 27 c1wtaA_ not modelled 99.9 15 PDB header:transferase Chain: A: PDB Molecule:5'-methylthioadenosine phosphorylase; PDBTitle: crystal structure of 5'-deoxy-5'-methylthioadenosine from aeropyrum2 pernix (r32 form) 28 d1g2oa_ not modelled 99.9 12 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 29 d1v4na_ not modelled 99.9 13 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 30 c3khsB_ not modelled 99.9 15 PDB header:hydrolase Chain: B: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: crystal structure of grouper iridovirus purine nucleoside2 phosphorylase 31 d1vmka_ not modelled 99.8 9 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 32 c2p4sA_ not modelled 99.8 12 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: structure of purine nucleoside phosphorylase from anopheles gambiae in2 complex with dadme-immh 33 d1cb0a_ not modelled 99.8 13 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 34 c1yr3A_ not modelled 99.8 13 PDB header:transferase Chain: A: PDB Molecule:xanthosine phosphorylase; PDBTitle: escherichia coli purine nucleoside phosphorylase ii, the2 product of the xapa gene 35 d1qe5a_ not modelled 99.8 15 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 36 c1tcvB_ not modelled 99.8 10 PDB header:transferase Chain: B: PDB Molecule:purine-nucleoside phosphorylase; PDBTitle: crystal structure of the purine nucleoside phosphorylase2 from schistosoma mansoni in complex with non-detergent3 sulfobetaine 195 and acetate 37 c3la8A_ not modelled 99.8 10 PDB header:transferase Chain: A: PDB Molecule:putative purine nucleoside phosphorylase; PDBTitle: the crystal structure of smu.1229 from streptococcus mutans ua159 38 d3bgsa1 not modelled 99.8 15 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 39 d3pnpa_ not modelled 99.8 13 Fold:Phosphorylase/hydrolase-like Superfamily:Purine and uridine phosphorylases Family:Purine and uridine phosphorylases 40 c3ggsA_ not modelled 99.7 12 PDB header:transferase Chain: A: PDB Molecule:purine nucleoside phosphorylase; PDBTitle: human purine nucleoside phosphorylase double mutant e201q,n243d2 complexed with 2-fluoro-2'-deoxyadenosine 41 d1ixka_ not modelled 74.3 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun 42 d1sv6a_ not modelled 66.4 20 Fold:FAH Superfamily:FAH Family:FAH 43 c3lywA_ not modelled 60.9 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ybbr family protein; PDBTitle: crystal structure of ybbr family protein dhaf_0833 from2 desulfitobacterium hafniense dcb-2. northeast structural3 genomics consortium target id dhr29b 44 c3m4xA_ not modelled 53.7 11 PDB header:transferase Chain: A: PDB Molecule:nol1/nop2/sun family protein; PDBTitle: structure of a ribosomal methyltransferase 45 c2yxlA_ not modelled 48.7 16 PDB header:transferase Chain: A: PDB Molecule:450aa long hypothetical fmu protein; PDBTitle: crystal structure of ph0851 46 c2eb5D_ not modelled 44.0 14 PDB header:lyase Chain: D: PDB Molecule:2-oxo-hept-3-ene-1,7-dioate hydratase; PDBTitle: crystal structure of hpcg complexed with oxalate 47 d1nr9a_ not modelled 42.9 14 Fold:FAH Superfamily:FAH Family:FAH 48 d1sgva2 not modelled 41.2 23 Fold:Pseudouridine synthase Superfamily:Pseudouridine synthase Family:Pseudouridine synthase II TruB 49 d1gtta2 not modelled 40.8 18 Fold:FAH Superfamily:FAH Family:FAH 50 d2es9a1 not modelled 37.9 40 Fold:YoaC-like Superfamily:YoaC-like Family:YoaC-like 51 d1gpua3 not modelled 37.6 16 Fold:TK C-terminal domain-like Superfamily:TK C-terminal domain-like Family:Transketolase C-terminal domain-like 52 c3r6oA_ not modelled 37.1 18 PDB header:isomerase Chain: A: PDB Molecule:2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase; PDBTitle: crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7-2 dioateisomerase from mycobacterium abscessus 53 c2dfuB_ not modelled 36.7 13 PDB header:isomerase Chain: B: PDB Molecule:probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; PDBTitle: crystal structure of the 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase2 from thermus thermophilus hb8 54 c1ojhK_ not modelled 36.6 47 PDB header:protein binding Chain: K: PDB Molecule:nbla; PDBTitle: crystal structure of nbla from pcc 7120 55 d1ojha_ not modelled 35.0 47 Fold:NblA-like Superfamily:NblA-like Family:NblA-like 56 c1sqgA_ not modelled 34.6 18 PDB header:transferase Chain: A: PDB Molecule:sun protein; PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution 57 d1gtta1 not modelled 33.8 21 Fold:FAH Superfamily:FAH Family:FAH 58 c3g7gG_ not modelled 32.5 19 PDB header:structural genomics, unknown function Chain: G: PDB Molecule:upf0311 protein ca_c3321; PDBTitle: crystal structure of the protein with unknown function from2 clostridium acetobutylicum atcc 824 59 d1nkqa_ not modelled 31.1 29 Fold:FAH Superfamily:FAH Family:FAH 60 d1qcza_ not modelled 30.1 20 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 61 c1a4iB_ not modelled 30.0 16 PDB header:oxidoreductase Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase / PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase 62 d2cl5a1 not modelled 26.5 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:COMT-like 63 d1b0aa1 not modelled 25.8 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 64 c3qdfA_ not modelled 25.3 18 PDB header:isomerase Chain: A: PDB Molecule:2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; PDBTitle: crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase2 from mycobacterium marinum 65 c3c5oD_ not modelled 25.1 17 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:upf0311 protein rpa1785; PDBTitle: crystal structure of the conserved protein of unknown function rpa17852 from rhodopseudomonas palustris 66 c1wzoC_ not modelled 24.7 14 PDB header:isomerase Chain: C: PDB Molecule:hpce; PDBTitle: crystal structure of the hpce from thermus thermophilus hb8 67 c3p2oA_ not modelled 23.7 16 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 68 d1sawa_ not modelled 22.9 13 Fold:FAH Superfamily:FAH Family:FAH 69 d1a4ia1 not modelled 22.8 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 70 d1p9ea_ not modelled 22.4 24 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Methyl parathion hydrolase 71 c1p9eA_ not modelled 22.4 24 PDB header:hydrolase Chain: A: PDB Molecule:methyl parathion hydrolase; PDBTitle: crystal structure analysis of methyl parathion hydrolase from2 pseudomonas sp wbc-3 72 c2h31A_ not modelled 21.9 15 PDB header:ligase, lyase Chain: A: PDB Molecule:multifunctional protein ade2; PDBTitle: crystal structure of human paics, a bifunctional carboxylase and2 synthetase in purine biosynthesis 73 d1sqga2 not modelled 21.9 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun 74 d1o4va_ not modelled 21.6 22 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 75 c3p2oB_ not modelled 21.5 16 PDB header:oxidoreductase, hydrolase Chain: B: PDB Molecule:bifunctional protein fold; PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni 76 c3eshB_ not modelled 21.2 27 PDB header:hydrolase Chain: B: PDB Molecule:protein similar to metal-dependent hydrolase; PDBTitle: crystal structure of a probable metal-dependent hydrolase2 from staphylococcus aureus. northeast structural genomics3 target zr314 77 c3m6wA_ not modelled 19.7 17 PDB header:transferase Chain: A: PDB Molecule:rrna methylase; PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine 78 c2q1dX_ not modelled 18.3 13 PDB header:lyase Chain: X: PDB Molecule:2-keto-3-deoxy-d-arabinonate dehydratase; PDBTitle: 2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and2 2,5-dioxopentanoate 79 c2k5jB_ not modelled 17.8 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein yiif; PDBTitle: solution structure of protein yiif from shigella flexneri2 serotype 5b (strain 8401) . northeast structural genomics3 consortium target sft1 80 c3l53F_ not modelled 17.6 18 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:putative fumarylacetoacetate isomerase/hydrolase; PDBTitle: crystal structure of a putative fumarylacetoacetate2 isomerase/hydrolase from oleispira antarctica 81 d1sr9a3 not modelled 17.6 23 Fold:2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain Superfamily:2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain Family:2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 82 c3peiA_ not modelled 16.7 18 PDB header:hydrolase Chain: A: PDB Molecule:cytosol aminopeptidase; PDBTitle: crystal structure of cytosol aminopeptidase from francisella2 tularensis 83 d1xmpa_ not modelled 15.6 22 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 84 c1zmrA_ not modelled 15.0 17 PDB header:transferase Chain: A: PDB Molecule:phosphoglycerate kinase; PDBTitle: crystal structure of the e. coli phosphoglycerate kinase 85 d1n08a_ not modelled 15.0 28 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin kinase-like Family:ATP-dependent riboflavin kinase-like 86 c2gfqC_ not modelled 14.9 24 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:upf0204 protein ph0006; PDBTitle: structure of protein of unknown function ph0006 from pyrococcus2 horikoshii 87 d2ja9a1 not modelled 14.9 36 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 88 d1vqod1 not modelled 14.5 26 Fold:RL5-like Superfamily:RL5-like Family:Ribosomal protein L5 89 c2x4lA_ not modelled 14.0 16 PDB header:transport Chain: A: PDB Molecule:ferric-siderophore receptor protein; PDBTitle: crystal structure of dese, a ferric-siderophore receptor2 protein from streptomyces coelicolor 90 c3rggD_ not modelled 12.6 15 PDB header:lyase Chain: D: PDB Molecule:phosphoribosylaminoimidazole carboxylase, pure protein; PDBTitle: crystal structure of treponema denticola pure bound to air 91 c2equA_ not modelled 12.4 33 PDB header:protein binding Chain: A: PDB Molecule:phd finger protein 20-like 1; PDBTitle: solution structure of the tudor domain of phd finger2 protein 20-like 1 92 d1oh1a_ not modelled 12.2 43 Fold:Streptavidin-like Superfamily:beta-Barrel protease inhibitors Family:Staphostatin 93 d1bl0a2 not modelled 12.0 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:AraC type transcriptional activator 94 d2nn6g1 not modelled 11.8 21 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 95 d1hyoa2 not modelled 11.8 22 Fold:FAH Superfamily:FAH Family:FAH 96 c3f6hA_ not modelled 11.6 18 PDB header:transferase Chain: A: PDB Molecule:alpha-isopropylmalate synthase; PDBTitle: crystal structure of the regulatory domain of licms in2 complexed with isoleucine - type iii 97 d1b12a_ not modelled 11.5 29 Fold:LexA/Signal peptidase Superfamily:LexA/Signal peptidase Family:Type 1 signal peptidase 98 c3trhI_ not modelled 11.5 20 PDB header:lyase Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii 99 c1dfwA_ not modelled 11.3 57 PDB header:immune system Chain: A: PDB Molecule:lung surfactant protein b; PDBTitle: conformational mapping of the n-terminal segment of2 surfactant protein b in lipid using 13c-enhanced fourier3 transform infrared spectroscopy (ftir)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0