Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	A	Y	I	A	K	Q	R	Q	I	S	F	V	K	S	H	F	S	R	Q	L	E	E	R	L	G	L	I	E	V	Q	A	P	I	L	S	R	V	G	D	G	T	Q	D	N	L	S	G	C	E	K	A	V	Q	V	K	V	K
Secondary structure
SS confidence
Disorder		?	?	?																														?	?		?	?	?	?	?			?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	L	P	D	A	Q	F	E	V	V	H	S	L	A	K	W	K	R	Q	T	L	G	Q	H	D	F	S	A	G	E	G	L	Y	T	H	M	K	A	L	R	P	D	E	D	R	L	S	P	L	H	S	V	Y	V	D	Q	W	D	W	E
Secondary structure
SS confidence
Disorder																																										?			?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	V	M	G	D	G	E	R	Q	F	S	T	L	K	S	T	V	E	A	I	W	A	G	I	K	A	T	E	A	A	V	S	E	E	F	G	L	A	P	F	L	P	D	Q	I	H	F	V	H	S	Q	E	L	L	S	R	Y	P	D	L
Secondary structure
SS confidence
Disorder																																						?	?	?	?	?	?	?																?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	A	K	G	R	E	R	A	I	A	K	D	L	G	A	V	F	L	V	G	I	G	G	K	L	S	D	G	H	R	H	D	V	R	A	P	D	Y	D	D	W	S	T	P	S	E	L	G	H	A	G	L	N	G	D	I	L	V	W	N
Secondary structure
SS confidence
Disorder		?																									?	?	?	?	?	?	?	?	?	?		?	?							?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	V	L	E	D	A	F	E	L	S	S	M	G	I	R	V	D	A	D	T	L	K	H	Q	L	A	L	T	G	D	E	D	R	L	E	L	E	W	H	Q	A	L	L	R	G	E	M	P	Q	T	I	G	G	G	I	G	Q	S	R	L
Secondary structure
SS confidence
Disorder										?																			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330
Sequence		T	M	L	L	L	Q	L	P	H	I	G	Q	V	Q	C	G	V	W	P	A	A	V	R	E	S	V	P	S	L	L
Secondary structure
SS confidence
Disorder																													?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 12as chain A Region: 4 - 330 Aligned: 327 Modelled: 327 Confidence: 100.0% Identity: 99% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1nnh chain A Region: 1 - 315 Aligned: 271 Modelled: 302 Confidence: 99.8% Identity: 18% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1l0w chain A domain 3 Region: 1 - 315 Aligned: 284 Modelled: 298 Confidence: 99.6% Identity: 18% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1c0a chain A domain 3 Region: 1 - 315 Aligned: 278 Modelled: 298 Confidence: 99.5% Identity: 20% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 3g1z chain B Region: 1 - 315 Aligned: 281 Modelled: 307 Confidence: 99.3% Identity: 13% PDB header:ligase Chain: B: PDB Molecule:putative lysyl-trna synthetase; PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium Phyre2 PDB 1bbu chain A domain 2 Region: 1 - 315 Aligned: 278 Modelled: 298 Confidence: 99.3% Identity: 15% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 3m4q chain A Region: 1 - 315 Aligned: 265 Modelled: 276 Confidence: 99.3% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative; PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs) Phyre2 PDB 1wyd chain B Region: 1 - 315 Aligned: 280 Modelled: 292 Confidence: 99.2% Identity: 17% PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii Phyre2 PDB 1e1o chain A domain 2 Region: 1 - 315 Aligned: 276 Modelled: 308 Confidence: 99.2% Identity: 16% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 2xgt chain B Region: 1 - 315 Aligned: 279 Modelled: 310 Confidence: 99.1% Identity: 16% PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate Phyre2 PDB 1x55 chain A Region: 1 - 315 Aligned: 280 Modelled: 304 Confidence: 99.1% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue Phyre2 PDB 1asy chain A Region: 1 - 315 Aligned: 281 Modelled: 295 Confidence: 99.0% Identity: 17% PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp Phyre2 PDB 1b8a chain B Region: 1 - 315 Aligned: 276 Modelled: 293 Confidence: 99.0% Identity: 19% PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase Phyre2 PDB 3e9h chain B Region: 1 - 315 Aligned: 275 Modelled: 280 Confidence: 99.0% Identity: 21% PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine Phyre2 PDB 1e22 chain A Region: 1 - 315 Aligned: 275 Modelled: 298 Confidence: 98.9% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp Phyre2 PDB 3bju chain B Region: 1 - 315 Aligned: 278 Modelled: 309 Confidence: 98.9% Identity: 17% PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase Phyre2 PDB 3i7f chain A Region: 61 - 315 Aligned: 235 Modelled: 249 Confidence: 98.9% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica Phyre2 PDB 1b8a chain A domain 2 Region: 1 - 315 Aligned: 280 Modelled: 295 Confidence: 98.8% Identity: 19% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1eqr chain C Region: 1 - 315 Aligned: 267 Modelled: 283 Confidence: 98.7% Identity: 22% PDB header:ligase Chain: C: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli Phyre2 PDB 1eov chain A domain 2 Region: 1 - 315 Aligned: 278 Modelled: 307 Confidence: 98.6% Identity: 18% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 1 d12asa_ 2 d1nnha_ 3 d1l0wa3 4 d1c0aa3 5 c3g1zB_ 6 d1bbua2 7 c3m4qA_ 8 c1wydB_ 9 d1e1oa2 10 c2xgtB_ 11 c1x55A_ 12 c1asyA_ 13 c1b8aB_ 14 c3e9hB_ 15 c1e22A_ 16 c3bjuB_ 17 c3i7fA_ 18 d1b8aa2 19 c1eqrC_ 20 d1eova2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d12asa_ 100.0 99 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 2 d1nnha_ 99.8 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 3 d1l0wa3 99.6 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 4 d1c0aa3 99.5 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 5 c3g1zB_ 99.3 13 PDB header:ligase Chain: B: PDB Molecule:putative lysyl-trna synthetase; PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium 6 d1bbua2 99.3 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 7 c3m4qA_ 99.3 17 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative; PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs) 8 c1wydB_ 99.2 17 PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii 9 d1e1oa2 99.2 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 10 c2xgtB_ 99.1 16 PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate 11 c1x55A_ 99.1 19 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue 12 c1asyA_ 99.0 17 PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp 13 c1b8aB_ 99.0 19 PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase 14 c3e9hB_ 99.0 21 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine 15 c1e22A_ 98.9 20 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp 16 c3bjuB_ 98.9 17 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase 17 c3i7fA_ 98.9 17 PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica 18 d1b8aa2 98.8 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 19 c1eqrC_ 98.7 22 PDB header:ligase Chain: C: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli 20 d1eova2 98.6 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 21 c1n9wA_ not modelled 98.6 20 PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus 22 d1n9wa2 not modelled 98.6 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 23 c1efwA_ not modelled 98.1 26 PDB header:ligase/rna Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli 24 c2znjB_ not modelled 95.1 17 PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense 25 c1b70A_ not modelled 94.1 21 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase; PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine 26 d1jjca_ not modelled 93.3 22 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 27 c3l4gI_ not modelled 92.2 24 PDB header:ligase Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 28 c3mf2B_ not modelled 87.5 23 PDB header:ligase Chain: B: PDB Molecule:bll0957 protein; PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp 29 d1kmma2 not modelled 83.4 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 30 d1h4vb2 not modelled 72.6 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 31 d1p3qq_ not modelled 69.1 32 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:CUE domain 32 c3qo8A_ not modelled 67.6 20 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of seryl-trna synthetase from candida albicans 33 c2du7C_ not modelled 65.4 14 PDB header:ligase Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase 34 c2zimA_ not modelled 62.5 17 PDB header:ligase Chain: A: PDB Molecule:pyrrolysyl-trna synthetase; PDBTitle: pyrrolysyl-trna synthetase bound to adenylated pyrrolysine and2 pyrophosphate 35 c3pcoC_ not modelled 62.4 24 PDB header:ligase Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 36 d1qe0a2 not modelled 58.2 29 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 37 c2rhqA_ not modelled 54.1 19 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 38 d2a7va1 not modelled 52.7 16 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:GABA-aminotransferase-like 39 c2a7vA_ not modelled 52.7 16 PDB header:transferase Chain: A: PDB Molecule:serine hydroxymethyltransferase; PDBTitle: human mitochondrial serine hydroxymethyltransferase 2 40 c3racA_ not modelled 52.3 16 PDB header:ligase Chain: A: PDB Molecule:histidine-trna ligase; PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446. 41 c3lm3A_ not modelled 42.6 23 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative glycoside hydrolase/deacetylase2 (bdi_3119) from parabacteroides distasonis at 1.44 a resolution 42 c2du4B_ not modelled 41.6 22 PDB header:ligase/rna Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys 43 c2dq3A_ not modelled 37.5 26 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of aq_298 44 c3errB_ not modelled 35.0 25 PDB header:ligase Chain: B: PDB Molecule:fusion protein of microtubule binding domain from PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase 45 d1ir1s_ not modelled 34.9 23 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 46 c1wleB_ not modelled 32.8 25 PDB header:ligase Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate 47 c1sryB_ not modelled 32.2 25 PDB header:ligase(synthetase) Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution 48 c2dq0A_ not modelled 32.0 25 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog 49 d1gk8i_ not modelled 31.2 27 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 50 d2v6ai1 not modelled 28.5 26 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 51 d1ej7s_ not modelled 28.3 19 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 52 d1unda_ not modelled 27.1 21 Fold:VHP, Villin headpiece domain Superfamily:VHP, Villin headpiece domain Family:VHP, Villin headpiece domain 53 d1unca_ not modelled 26.8 36 Fold:VHP, Villin headpiece domain Superfamily:VHP, Villin headpiece domain Family:VHP, Villin headpiece domain 54 d1yu8x1 not modelled 26.7 36 Fold:VHP, Villin headpiece domain Superfamily:VHP, Villin headpiece domain Family:VHP, Villin headpiece domain 55 d1uzdc1 not modelled 26.4 26 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 56 d8ruci_ not modelled 26.2 23 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 57 d1wdds_ not modelled 25.4 23 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 58 d1qzpa_ not modelled 23.4 43 Fold:VHP, Villin headpiece domain Superfamily:VHP, Villin headpiece domain Family:VHP, Villin headpiece domain 59 d1ny722 not modelled 23.3 70 Fold:Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily:Positive stranded ssRNA viruses Family:Comoviridae-like VP 60 c2l3xA_ not modelled 23.3 43 PDB header:protein binding Chain: A: PDB Molecule:ablim2 protein; PDBTitle: villin head piece domain of human ablim2 61 d1ujsa_ not modelled 23.2 43 Fold:VHP, Villin headpiece domain Superfamily:VHP, Villin headpiece domain Family:VHP, Villin headpiece domain 62 d1seta2 not modelled 22.4 25 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 63 c2k6nA_ not modelled 22.4 29 PDB header:structural protein Chain: A: PDB Molecule:supervillin; PDBTitle: solution structure of human supervillin headpiece, minimized2 average 64 d1pgl22 not modelled 20.9 70 Fold:Nucleoplasmin-like/VP (viral coat and capsid proteins) Superfamily:Positive stranded ssRNA viruses Family:Comoviridae-like VP 65 d1uj8a1 not modelled 20.7 47 Fold:Another 3-helical bundle Superfamily:IscX-like Family:IscX-like 66 d1yu5x1 not modelled 20.4 36 Fold:VHP, Villin headpiece domain Superfamily:VHP, Villin headpiece domain Family:VHP, Villin headpiece domain 67 d2fnoa2 not modelled 20.1 19 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 68 c1jvnB_ not modelled 19.6 67 PDB header:transferase Chain: B: PDB Molecule:bifunctional histidine biosynthesis protein hishf; PDBTitle: crystal structure of imidazole glycerol phosphate synthase: a tunnel2 through a (beta/alpha)8 barrel joins two active sites 69 c2k29A_ not modelled 18.3 17 PDB header:transcription Chain: A: PDB Molecule:antitoxin relb; PDBTitle: structure of the dbd domain of e. coli antitoxin relb 70 c2z4tA_ not modelled 17.9 28 PDB header:transferase Chain: A: PDB Molecule:beta-galactoside alpha-2,6-sialyltransferase; PDBTitle: crystal structure of vibrionaceae photobacterium sp. jt-ish-224 2,6-2 sialyltransferase in a ternary complex with donor product cmp and3 accepter substrate lactose 71 d1htwa_ not modelled 17.3 24 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:YjeE-like 72 d1uzhc1 not modelled 17.2 26 Fold:RuBisCO, small subunit Superfamily:RuBisCO, small subunit Family:RuBisCO, small subunit 73 c2zwiA_ not modelled 17.0 18 PDB header:transferase Chain: A: PDB Molecule:alpha-/beta-galactoside alpha-2,3-sialyltransferase; PDBTitle: crystal structure of alpha/beta-galactoside alpha-2,3-2 sialyltransferase from a luminous marine bacterium, photobacterium3 phosphoreum 74 d1p3qr_ not modelled 14.5 33 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:CUE domain 75 c1z7nB_ not modelled 13.1 12 PDB header:transferase Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate 76 c1xahA_ not modelled 12.8 7 PDB header:lyase Chain: A: PDB Molecule:3-dehydroquinate synthase; PDBTitle: crystal structure of staphlyococcus aureus 3-dehydroquinate2 synthase (dhqs) in complex with zn2+ and nad+ 77 d2cbpa_ not modelled 12.1 41 Fold:Cupredoxin-like Superfamily:Cupredoxins Family:Plastocyanin/azurin-like 78 c2pmfA_ not modelled 11.9 12 PDB header:ligase Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant 79 c2bfuL_ not modelled 11.6 64 PDB header:virus Chain: L: PDB Molecule:cowpea mosaic virus, large (l) subunit; PDBTitle: x-ray structure of cpmv top component 80 c2j3mA_ not modelled 10.6 25 PDB header:ligase Chain: A: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol 81 d1vqoi1 not modelled 9.9 29 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Ribosomal protein L11, C-terminal domain Family:Ribosomal protein L11, C-terminal domain 82 c1vq8I_ not modelled 9.9 29 PDB header:ribosome Chain: I: PDB Molecule:50s ribosomal protein l11p; PDBTitle: the structure of ccda-phe-cap-bio and the antibiotic sparsomycin bound2 to the large ribosomal subunit of haloarcula marismortui 83 c2flyA_ not modelled 9.7 20 PDB header:hormone/growth factor Chain: A: PDB Molecule:proadrenomedullin n-20 terminal peptide; PDBTitle: proadrenomedullin n-terminal 20 peptide 84 c3uhjE_ not modelled 9.5 35 PDB header:oxidoreductase Chain: E: PDB Molecule:probable glycerol dehydrogenase; PDBTitle: crystal structure of a probable glycerol dehydrogenase from2 sinorhizobium meliloti 1021 85 d2gycg1 not modelled 9.4 57 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Ribosomal protein L11, C-terminal domain Family:Ribosomal protein L11, C-terminal domain 86 c2zkri_ not modelled 9.3 57 PDB header:ribosomal protein/rna Chain: I: PDB Molecule:rna expansion segment es15 part i; PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map 87 d1hc8a_ not modelled 9.2 71 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Ribosomal protein L11, C-terminal domain Family:Ribosomal protein L11, C-terminal domain 88 c2dzlA_ not modelled 9.1 37 PDB header:structural genomics unknown function Chain: A: PDB Molecule:protein fam100b; PDBTitle: solution structure of the uba domain in human protein2 fam100b 89 d1rw3a_ not modelled 9.0 11 Fold:DNA/RNA polymerases Superfamily:DNA/RNA polymerases Family:Reverse transcriptase 90 d2ga1a1 not modelled 8.7 35 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Alr1493-like 91 c2vacA_ not modelled 8.4 31 PDB header:transferase Chain: A: PDB Molecule:twinfilin-2; PDBTitle: structure of n-terminal actin depolymerizing factor2 homology (adf-h) domain of human twinfilin-2 92 c2nysA_ not modelled 8.4 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:agr_c_3712p; PDBTitle: x-ray crystal structure of protein agr_c_3712 from2 agrobacterium tumefaciens. northeast structural genomics3 consortium target atr88. 93 d2nysa1 not modelled 8.4 28 Fold:SspB-like Superfamily:SspB-like Family:AGR C 3712p-like 94 d2pkqo2 not modelled 8.3 23 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:GAPDH-like 95 c1zzgB_ not modelled 8.0 33 PDB header:isomerase Chain: B: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of hypothetical protein tt0462 from thermus2 thermophilus hb8 96 c2l0gA_ not modelled 8.0 83 PDB header:protein binding Chain: A: PDB Molecule:dna polymerase iota; PDBTitle: solution nmr structure of ubiquitin-binding motif (ubm2) of human2 polymerase iota 97 d1obfo2 not modelled 8.0 23 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:GAPDH-like 98 d1gsua2 not modelled 7.8 24 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 99 c2khuA_ not modelled 7.5 83 PDB header:transferase/protein binding Chain: A: PDB Molecule:immunoglobulin g-binding protein g, dna PDBTitle: solution structure of the ubiquitin-binding motif of human2 polymerase iota

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0