Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP39308
DateThu Jan 5 11:59:11 GMT 2012
Unique Job ID9dccec09a4b5ac89

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2atra1
Top template information
Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
Confidence and coverage
Confidence: 40.4% Coverage: 28%
75 residues ( 28% of your sequence) have been modelled with 40.4% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTLPTTIYSFPAYLSRFSSTDKPVKLKFHQYARATLLSNRGRDHNCDGRRTVEIHKLDLS
Secondary structure 





















SS confidence 



























































Disorder  ???????





























?
??????????










Disorder confidence 



























































 
   .........70.........80.........90.........100.........110.........120
Sequence  DWQAFNKLATRCNAYDGITMNGDNSFGWNHEATLDNIHAQKYNKAYAGARLTAELKYLLQ
Secondary structure 









SS confidence 



























































Disorder 
















?



























?
??









Disorder confidence 



























































 
   .........130.........140.........150.........160.........170.........180
Sequence  DVESFEPNSKYTIHEVVLGPGYGTPDYTGQTIGYVVTLPAQMPNCWSSELPTIDLYIDQL
Secondary structure 
































SS confidence 



























































Disorder 
??
































??

???????












Disorder confidence 



























































 
   .........190.........200.........210.........220.........230.........240
Sequence  RTVTGVSNALGFIIAALLNAYSDLPHDLKIGLRSLSSSAAIYSGLGFERVPQERDISCAR
Secondary structure 





















SS confidence 



























































Disorder 
???













?
















?
???


















Disorder confidence 



























































 
   .........250.........260....
Sequence  MYLTPANHPDLWTQENGEWIYLRN
Secondary structure 









SS confidence 























Disorder 


















?
???
Disorder confidence 























 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2atr chain A domain 1

3D model

Region: 149 - 232
Aligned: 75
Modelled: 84
Confidence: 40.4%
Identity: 13%
Fold: Acyl-CoA N-acyltransferases (Nat)
Superfamily: Acyl-CoA N-acyltransferases (Nat)
Family: N-acetyl transferase, NAT

Phyre2

PDB 3s6f chain A

3D model

Region: 149 - 249
Aligned: 86
Modelled: 96
Confidence: 31.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:hypothetical acetyltransferase;
PDBTitle: crystal structure of a hypotetical acetyltransferase (dr_1678) from2 deinococcus radiodurans at 1.19 a resolution

Phyre2

PDB 2q9o chain A domain 2

3D model

Region: 52 - 166
Aligned: 95
Modelled: 115
Confidence: 26.0%
Identity: 22%
Fold: Cupredoxin-like
Superfamily: Cupredoxins
Family: Multidomain cupredoxins

Phyre2

PDB 1yf9 chain A domain 1

3D model

Region: 107 - 163
Aligned: 56
Modelled: 57
Confidence: 23.9%
Identity: 23%
Fold: UBC-like
Superfamily: UBC-like
Family: UBC-related

Phyre2

PDB 1yx0 chain A domain 1

3D model

Region: 149 - 230
Aligned: 73
Modelled: 82
Confidence: 20.7%
Identity: 14%
Fold: Acyl-CoA N-acyltransferases (Nat)
Superfamily: Acyl-CoA N-acyltransferases (Nat)
Family: N-acetyl transferase, NAT

Phyre2

PDB 2xr4 chain A

3D model

Region: 167 - 179
Aligned: 13
Modelled: 13
Confidence: 19.7%
Identity: 46%
PDB header:sugar binding protein
Chain: A: PDB Molecule:lectin;
PDBTitle: c-terminal domain of bc2l-c lectin from burkholderia cenocepacia

Phyre2

PDB 1m2o chain A

3D model

Region: 145 - 222
Aligned: 67
Modelled: 71
Confidence: 19.3%
Identity: 22%
PDB header:protein transport/signaling protein
Chain: A: PDB Molecule:protein transport protein sec23;
PDBTitle: crystal structure of the sec23-sar1 complex

Phyre2

PDB 2cho chain A domain 2

3D model

Region: 127 - 163
Aligned: 37
Modelled: 37
Confidence: 18.5%
Identity: 30%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: alpha-D-glucuronidase/Hyaluronidase catalytic domain

Phyre2

PDB 1fjr chain A

3D model

Region: 205 - 257
Aligned: 53
Modelled: 53
Confidence: 17.7%
Identity: 23%
Fold: Methuselah ectodomain
Superfamily: Methuselah ectodomain
Family: Methuselah ectodomain

Phyre2

PDB 1j58 chain A

3D model

Region: 231 - 262
Aligned: 32
Modelled: 31
Confidence: 17.3%
Identity: 22%
Fold: Double-stranded beta-helix
Superfamily: RmlC-like cupins
Family: Germin/Seed storage 7S protein

Phyre2

PDB 2vnv chain C

3D model

Region: 167 - 179
Aligned: 13
Modelled: 13
Confidence: 15.6%
Identity: 31%
PDB header:sugar-binding protein
Chain: C: PDB Molecule:bcla;
PDBTitle: crystal structure of bcla lectin from burkholderia2 cenocepacia in complex with alpha-methyl-mannoside at 1.73 angstrom resolution

Phyre2

PDB 3ijr chain F

3D model

Region: 156 - 198
Aligned: 43
Modelled: 40
Confidence: 15.0%
Identity: 21%
PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+

Phyre2

PDB 1ekg chain A

3D model

Region: 245 - 264
Aligned: 20
Modelled: 20
Confidence: 14.9%
Identity: 20%
Fold: N domain of copper amine oxidase-like
Superfamily: Frataxin/Nqo15-like
Family: Frataxin-like

Phyre2

PDB 1y9w chain A domain 1

3D model

Region: 149 - 237
Aligned: 80
Modelled: 86
Confidence: 14.7%
Identity: 15%
Fold: Acyl-CoA N-acyltransferases (Nat)
Superfamily: Acyl-CoA N-acyltransferases (Nat)
Family: N-acetyl transferase, NAT

Phyre2

PDB 2cbi chain A domain 2

3D model

Region: 127 - 163
Aligned: 37
Modelled: 37
Confidence: 14.6%
Identity: 22%
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Family: alpha-D-glucuronidase/Hyaluronidase catalytic domain

Phyre2

PDB 1c4z chain D

3D model

Region: 110 - 163
Aligned: 52
Modelled: 54
Confidence: 13.3%
Identity: 19%
Fold: UBC-like
Superfamily: UBC-like
Family: UBC-related

Phyre2

PDB 3nva chain B

3D model

Region: 53 - 149
Aligned: 93
Modelled: 97
Confidence: 13.1%
Identity: 20%
PDB header:ligase
Chain: B: PDB Molecule:ctp synthase;
PDBTitle: dimeric form of ctp synthase from sulfolobus solfataricus

Phyre2

PDB 2boi chain A

3D model

Region: 167 - 179
Aligned: 13
Modelled: 13
Confidence: 12.4%
Identity: 15%
PDB header:lectin
Chain: A: PDB Molecule:cv-iil lectin;
PDBTitle: 1.1a structure of chromobacterium violaceum lectin cv2l in2 complex with alpha-methyl-fucoside

Phyre2

PDB 1qd1 chain A domain 2

3D model

Region: 44 - 130
Aligned: 86
Modelled: 87
Confidence: 12.4%
Identity: 14%
Fold: Ferredoxin-like
Superfamily: Formiminotransferase domain of formiminotransferase-cyclodeaminase.
Family: Formiminotransferase domain of formiminotransferase-cyclodeaminase.

Phyre2

PDB 3gem chain C

3D model

Region: 183 - 237
Aligned: 52
Modelled: 55
Confidence: 12.3%
Identity: 21%
PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of short-chain dehydrogenase from pseudomonas2 syringae

Phyre2
1

d2atra1
2

c3s6fA_
3

d2q9oa2
4

d1yf9a1
5

d1yx0a1
6

c2xr4A_
7

c1m2oA_
8

d2choa2
9

d1fjra_
10

d1j58a_
11

c2vnvC_
12

c3ijrF_
13

d1ekga_
14

d1y9wa1
15

d2cbia2
16

d1c4zd_
17

c3nvaB_
18

c2boiA_
19

d1qd1a2
20

c3gemC_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43



44



45



46



47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



65



66



67



68






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2atra1



40.4 13 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
2c3s6fA_



31.0 24 PDB header:transferase
Chain: A: PDB Molecule:hypothetical acetyltransferase;
PDBTitle: crystal structure of a hypotetical acetyltransferase (dr_1678) from2 deinococcus radiodurans at 1.19 a resolution
3d2q9oa2



26.0 22 Fold:Cupredoxin-like
Superfamily:Cupredoxins
Family:Multidomain cupredoxins
4d1yf9a1



23.9 23 Fold:UBC-like
Superfamily:UBC-like
Family:UBC-related
5d1yx0a1



20.7 14 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
6c2xr4A_



19.7 46 PDB header:sugar binding protein
Chain: A: PDB Molecule:lectin;
PDBTitle: c-terminal domain of bc2l-c lectin from burkholderia cenocepacia
7c1m2oA_



19.3 22 PDB header:protein transport/signaling protein
Chain: A: PDB Molecule:protein transport protein sec23;
PDBTitle: crystal structure of the sec23-sar1 complex
8d2choa2



18.5 30 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:alpha-D-glucuronidase/Hyaluronidase catalytic domain
9d1fjra_



17.7 23 Fold:Methuselah ectodomain
Superfamily:Methuselah ectodomain
Family:Methuselah ectodomain
10d1j58a_



17.3 22 Fold:Double-stranded beta-helix
Superfamily:RmlC-like cupins
Family:Germin/Seed storage 7S protein
11c2vnvC_



15.6 31 PDB header:sugar-binding protein
Chain: C: PDB Molecule:bcla;
PDBTitle: crystal structure of bcla lectin from burkholderia2 cenocepacia in complex with alpha-methyl-mannoside at 1.73 angstrom resolution
12c3ijrF_



15.0 21 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
13d1ekga_



14.9 20 Fold:N domain of copper amine oxidase-like
Superfamily:Frataxin/Nqo15-like
Family:Frataxin-like
14d1y9wa1



14.7 15 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
15d2cbia2



14.6 22 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:alpha-D-glucuronidase/Hyaluronidase catalytic domain
16d1c4zd_



13.3 19 Fold:UBC-like
Superfamily:UBC-like
Family:UBC-related
17c3nvaB_



13.1 20 PDB header:ligase
Chain: B: PDB Molecule:ctp synthase;
PDBTitle: dimeric form of ctp synthase from sulfolobus solfataricus
18c2boiA_



12.4 15 PDB header:lectin
Chain: A: PDB Molecule:cv-iil lectin;
PDBTitle: 1.1a structure of chromobacterium violaceum lectin cv2l in2 complex with alpha-methyl-fucoside
19d1qd1a2



12.4 14 Fold:Ferredoxin-like
Superfamily:Formiminotransferase domain of formiminotransferase-cyclodeaminase.
Family:Formiminotransferase domain of formiminotransferase-cyclodeaminase.
20c3gemC_



12.3 21 PDB header:oxidoreductase
Chain: C: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of short-chain dehydrogenase from pseudomonas2 syringae
21d2nvuc1



not modelled 12.0 16 Fold:UBC-like
Superfamily:UBC-like
Family:UBC-related
22d2chha1



not modelled 11.8 23 Fold:Calcium-mediated lectin
Superfamily:Calcium-mediated lectin
Family:Calcium-mediated lectin
23d1uzva_



not modelled 11.4 23 Fold:Calcium-mediated lectin
Superfamily:Calcium-mediated lectin
Family:Calcium-mediated lectin
24c2xlfA_



not modelled 10.7 20 PDB header:metal binding protein
Chain: A: PDB Molecule:sll1785 protein;
PDBTitle: structure and metal-loading of a soluble periplasm cupro-protein:2 apo-cuca-closed (semet)
25d1h2ka_



not modelled 10.4 24 Fold:Double-stranded beta-helix
Superfamily:Clavaminate synthase-like
Family:Hypoxia-inducible factor HIF ihhibitor (FIH1)
26d1k2wa_



not modelled 10.2 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
27d2ga5a1



not modelled 10.2 32 Fold:N domain of copper amine oxidase-like
Superfamily:Frataxin/Nqo15-like
Family:Frataxin-like
28d1xeba_



not modelled 9.7 26 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
29c2xsbA_



not modelled 9.6 22 PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronoglucosaminidase;
PDBTitle: ogoga pugnac complex
30c3o2uB_



not modelled 9.5 19 PDB header:ligase
Chain: B: PDB Molecule:nedd8-conjugating enzyme ubc12;
PDBTitle: s. cerevisiae ubc12
31c2l7lB_



not modelled 9.2 70 PDB header:metal binding protein/transferase
Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type 1;
PDBTitle: solution structure of ca2+/calmodulin complexed with a peptide2 representing the calmodulin-binding domain of calmodulin kinase i
32c2jtmA_



not modelled 8.9 34 PDB header:dna binding protein
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: solution structure of sso6901 from sulfolobus solfataricus2 p2
33c2vxkA_



not modelled 8.9 18 PDB header:transferase
Chain: A: PDB Molecule:glucosamine 6-phosphate acetyltransferase;
PDBTitle: structural comparison between aspergillus fumigatus and2 human gna1
34c2npiD_



not modelled 8.8 50 PDB header:transcription
Chain: D: PDB Molecule:protein pcf11;
PDBTitle: clp1-atp-pcf11 complex
35c1mxeE_



not modelled 8.8 70 PDB header:metal binding protein
Chain: E: PDB Molecule:target sequence of rat calmodulin-dependent
PDBTitle: structure of the complex of calmodulin with the target2 sequence of camki
36c1mxeF_



not modelled 8.8 70 PDB header:metal binding protein
Chain: F: PDB Molecule:target sequence of rat calmodulin-dependent
PDBTitle: structure of the complex of calmodulin with the target2 sequence of camki
37c3gzaB_



not modelled 8.8 15 PDB header:hydrolase
Chain: B: PDB Molecule:putative alpha-l-fucosidase;
PDBTitle: crystal structure of putative alpha-l-fucosidase (np_812709.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.60 a resolution
38c2du7C_



not modelled 8.8 20 PDB header:ligase
Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase;
PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase
39d1hywa_



not modelled 8.2 42 Fold:gpW/XkdW-like
Superfamily:Head-to-tail joining protein W, gpW
Family:Head-to-tail joining protein W, gpW
40d1su3a1



not modelled 7.9 44 Fold:PGBD-like
Superfamily:PGBD-like
Family:MMP N-terminal domain
41c2cbjA_



not modelled 7.5 22 PDB header:hydrolase
Chain: A: PDB Molecule:hyaluronidase;
PDBTitle: structure of the clostridium perfringens nagj family 842 glycoside hydrolase, a homologue of human o-glcnacase in3 complex with pugnac
42d2ae6a1



not modelled 7.5 11 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
43c2qj8B_



not modelled 7.3 18 PDB header:hydrolase
Chain: B: PDB Molecule:mlr6093 protein;
PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution
44d1o8ba1



not modelled 7.2 27 Fold:NagB/RpiA/CoA transferase-like
Superfamily:NagB/RpiA/CoA transferase-like
Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain
45d1fasa_



not modelled 7.0 60 Fold:Snake toxin-like
Superfamily:Snake toxin-like
Family:Snake venom toxins
46d1ed7a_



not modelled 7.0 42 Fold:WW domain-like
Superfamily:Carbohydrate binding domain
Family:Carbohydrate binding domain
47d2jdca1



not modelled 6.7 13 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
48c3pvlA_



not modelled 6.7 20 PDB header:motor protein/protein transport
Chain: A: PDB Molecule:myosin viia isoform 1;
PDBTitle: structure of myosin viia myth4-ferm-sh3 in complex with the cen1 of2 sans
49d2fiwa1



not modelled 6.5 17 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
50d1slma1



not modelled 6.3 57 Fold:PGBD-like
Superfamily:PGBD-like
Family:MMP N-terminal domain
51d1wzva1



not modelled 6.2 20 Fold:UBC-like
Superfamily:UBC-like
Family:UBC-related
52d2fd6u1



not modelled 6.1 14 Fold:Snake toxin-like
Superfamily:Snake toxin-like
Family:Extracellular domain of cell surface receptors
53d1ejda_



not modelled 6.1 16 Fold:IF3-like
Superfamily:EPT/RTPC-like
Family:Enolpyruvate transferase, EPT
54d2gx8a1



not modelled 6.1 23 Fold:NIF3 (NGG1p interacting factor 3)-like
Superfamily:NIF3 (NGG1p interacting factor 3)-like
Family:NIF3 (NGG1p interacting factor 3)-like
55d1xs8a_



not modelled 6.0 23 Fold:YggX-like
Superfamily:YggX-like
Family:YggX-like
56d2qtva3



not modelled 6.0 21 Fold:vWA-like
Superfamily:vWA-like
Family:Trunk domain of Sec23/24
57d1ew4a_



not modelled 6.0 15 Fold:N domain of copper amine oxidase-like
Superfamily:Frataxin/Nqo15-like
Family:Frataxin-like
58d1yvoa1



not modelled 5.7 18 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-acetyl transferase, NAT
59d1bwva2



not modelled 5.6 18 Fold:Ferredoxin-like
Superfamily:RuBisCO, large subunit, small (N-terminal) domain
Family:Ribulose 1,5-bisphosphate carboxylase-oxygenase
60d2r7ca2



not modelled 5.5 33 Fold:Rotavirus NSP2 fragment, N-terminal domain
Superfamily:Rotavirus NSP2 fragment, N-terminal domain
Family:Rotavirus NSP2 fragment, N-terminal domain
61c3iuwA_



not modelled 5.5 46 PDB header:rna binding protein
Chain: A: PDB Molecule:activating signal cointegrator;
PDBTitle: crystal structure of activating signal cointegrator (np_814290.1) from2 enterococcus faecalis v583 at 1.58 a resolution
62c2pdoG_



not modelled 5.2 21 PDB header:transferase
Chain: G: PDB Molecule:acetyltransferase ypea;
PDBTitle: crystal structure of the putative acetyltransferase of gnat family2 from shigella flexneri
63c1iclA_



not modelled 5.2 40 PDB header:de novo protein
Chain: A: PDB Molecule:th1ox;
PDBTitle: solution structure of designed beta-sheet mini-protein th1ox
64d1o8bb1



not modelled 5.1 27 Fold:NagB/RpiA/CoA transferase-like
Superfamily:NagB/RpiA/CoA transferase-like
Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain
65d1j7db_



not modelled 5.1 29 Fold:UBC-like
Superfamily:UBC-like
Family:UBC-related
66c2w7tA_



not modelled 5.1 22 PDB header:ligase
Chain: A: PDB Molecule:putative cytidine triphosphate synthase;
PDBTitle: trypanosoma brucei ctps - glutaminase domain with bound2 acivicin
67d1yq2a2



not modelled 5.1 29 Fold:Immunoglobulin-like beta-sandwich
Superfamily:beta-Galactosidase/glucuronidase domain
Family:beta-Galactosidase/glucuronidase domain
68d1n10a2



not modelled 5.1 43 Fold:Double psi beta-barrel
Superfamily:Barwin-like endoglucanases
Family:Pollen allergen PHL P 1 N-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0