Phyre 2 Results for P16917

Email	l.a.kelley@imperial.ac.uk
Description	P16917
Date	Wed Jan 25 15:20:40 GMT 2012
Unique Job ID	9ae603be021ddcff

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2oy7A_

Top template information

PDB header:membrane protein
Chain: A: PDB Molecule:outer surface protein a;
PDBTitle: the crystal structure of ospa mutant

Confidence and coverage

Confidence:

96.5%

Coverage:

19%

269 residues ( 19% of your sequence) have been modelled with 96.5% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

338 residues ( 24%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M S G K P A A R Q G D M T Q Y G G S I V Q G S A G V R I G A P T G V A C S V C P G G V T S G H P V N P L L G A K V L P G

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ?
? ? ? ? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence E T D I A L P G P L P F I L S R T Y S S Y R T K T P A P V G S L G P G W K M P A D I R L Q L R D N T L I L S D N G G R S

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence L Y F E H L F P G E D G Y S R S E S L W L V R G G V A K L D E G H R L A A L W Q A L P E E L R L S P H R Y L A T N S P Q

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence G P W W L L G W C E R V P E A D E V L P A P L P P Y R V L T G L V D R F G R T Q T F H R E A A G E F S G E I T G V T D G

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence A W R H F R L V L T T Q A Q R A E E A R Q Q A I S G G T E P S A F P D T L P G Y T E Y G R D N G I R L S A V W L T H D P

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence E Y P E N L P A A P L V R Y G W T P R G E L A V V Y D R S G K Q V R S F T Y D D K Y R G R M V A H R H T G R P E I R Y R

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence Y D S D G R V T E Q L N P A G L S Y T Y Q Y E K D R I T I T D S L D R R E V L H T Q G E A G L K R V V K K E H A D G S V

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence T Q S Q F D A V G R L R A Q T D A A G R T T E Y S P D V V T G L I T R I T T P D G R A S A F Y Y N H H N Q L T S A T G P

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence D G L E L R R E Y D E L G R L I Q E T A P D G D I T R Y R Y D N P H S D L P C A T E D A T G S R K T M T W S R Y G Q L L

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence S F T D C S G Y V T R Y D H D R F G Q M T A V H R E E G L S Q Y R A Y D S R G Q L I A V K D T Q G H E T R Y E Y N I A G

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence D L T A V I A P D G S R N G T Q Y D A W G K A V R T T Q G G L T R S M E Y D A A G R V I R L T S E N G S H T T F R Y D V

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence L D R L I Q E T G F D G R T Q R Y H H D L T G K L I R S E D E G L V T H W H Y D E A D R L T H R T V K G E T A E R W Q Y

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence D E R G W L T D I S H I S E G H R V A V H Y R Y D E K G R L T G E R Q T V H H P Q T E A L L W Q H E T R H A Y N A Q G L

Secondary structure

SS confidence

Disorder
?
? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence A N R C I P D S L P A V E W L T Y G S G Y L A G M K L G D T P L V E Y T R D R L H R E T L R S F G R Y E L T T A Y T P A

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence G Q L Q S Q H L N S L L S D R D Y T W N D N G E L I R I S S P R Q T R S Y S Y S T T G R L T G V H T T A A N L D I R I P

Secondary structure

SS confidence

Disorder
?
?
?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence Y A T D P A G N R L P D P E L H P D S T L S M W P D N R I A R D A H Y L Y R Y D R H G R L T E K T D L I P E G V I R T D

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence D E R T H R Y H Y D S Q H R L V H Y T R T Q Y E E P L V E S R Y L Y D P L G R R V A K R V W R R E R D L T G W M S L S R

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence K P Q V T W Y G W D G D R L T T I Q N D R S R I Q T I Y Q P G S F T P L I R V E T A T G E L A K T Q R R S L A D A L Q Q

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence S G G E D G G S V V F P P V L V Q M L D R L E S E I L A D R V S E E S R R W L A S C G L T V E Q M Q N Q M D P V Y T P A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence R K I H L Y H C D H R G L P L A L I S T E G A T A W C A E Y D E W G N L L N E E N P H Q L Q Q L I R L P G Q Q Y D E E S

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence G L Y Y N R H R Y Y D P L Q G R Y I T Q D P I G L K G G W N L Y G Y Q L N P I S D I D P L G L S M W E D A K S G A C T N

Secondary structure

SS confidence

Disorder
?

Disorder confidence

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320

Sequence G L C G T L S A M I G P D K F D S I D S T A Y D A L N K I N S Q S I C E D K E F A G L I C K D N S G R Y F S T A P N R G

Secondary structure

SS confidence

Disorder
? ?
?
? ? ?
?
?
?
? ?
? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1330 . . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380

Sequence E R K G S Y P F N S P C P N G T E K V S A Y H T H G A D S H G E Y W D E I F S G K D E K I V K S K D N N I K S F Y L G T

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
? ?
? ?
? ? ? ? ? ?
? ?
?
? ? ? ?

Disorder confidence

. . . . . . . . . 1390 . . . . . . . . . 1400 . . . . . . . . . 1410 .

Sequence P S G N F K A I D N H G K E I T N R K G L P N V C R V H G N M

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2oy7 chain A

Region: 385 - 662
Aligned: 269
Modelled: 278
Confidence: 96.5%
Identity: 15%
PDB header:membrane protein
Chain: A: PDB Molecule:outer surface protein a;
PDBTitle: the crystal structure of ospa mutant

Phyre2

PDB 1hng chain A domain 1

Region: 1279 - 1347
Aligned: 69
Modelled: 69
Confidence: 92.7%
Identity: 19%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Family: V set domains (antibody variable domain-like)

Phyre2

PDB 1hnf chain A domain 1

Region: 1303 - 1347
Aligned: 45
Modelled: 45
Confidence: 68.3%
Identity: 16%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Family: V set domains (antibody variable domain-like)

Phyre2

PDB 1n7d chain A

Region: 472 - 688
Aligned: 217
Modelled: 217
Confidence: 67.7%
Identity: 12%
PDB header:lipid transport
Chain: A: PDB Molecule:low-density lipoprotein receptor;
PDBTitle: extracellular domain of the ldl receptor

Phyre2

PDB 1x3z chain A domain 1

Region: 1209 - 1242
Aligned: 33
Modelled: 34
Confidence: 39.1%
Identity: 18%
Fold: Cysteine proteinases
Superfamily: Cysteine proteinases
Family: Transglutaminase core

Phyre2

PDB 1osp chain O

Region: 366 - 558
Aligned: 173
Modelled: 180
Confidence: 33.3%
Identity: 16%
Fold: open-sided beta-meander
Superfamily: Outer surface protein
Family: Outer surface protein

Phyre2

PDB 2w8b chain B

Region: 347 - 599
Aligned: 243
Modelled: 253
Confidence: 31.4%
Identity: 12%
PDB header:protein transport/membrane protein
Chain: B: PDB Molecule:protein tolb;
PDBTitle: crystal structure of processed tolb in complex with pal

Phyre2

PDB 3e5z chain A

Region: 426 - 683
Aligned: 252
Modelled: 258
Confidence: 31.0%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative gluconolactonase;
PDBTitle: x-ray structure of the putative gluconolactonase in protein family2 pf08450. northeast structural genomics consortium target drr130.

Phyre2

PDB 3rwx chain A

Region: 62 - 78
Aligned: 17
Modelled: 15
Confidence: 25.0%
Identity: 18%
PDB header:transport protein
Chain: A: PDB Molecule:hypothetical bacterial outer membrane protein;
PDBTitle: crystal structure of a hypothetical bacterial outer membrane protein2 (bf2706) from bacteroides fragilis nctc 9343 at 2.40 a resolution

Phyre2

PDB 2j44 chain A domain 2

Region: 1238 - 1299
Aligned: 61
Modelled: 62
Confidence: 23.8%
Identity: 18%
Fold: Prealbumin-like
Superfamily: Starch-binding domain-like
Family: PUD-like

Phyre2

PDB 2ivz chain D

Region: 385 - 626
Aligned: 238
Modelled: 242
Confidence: 22.0%
Identity: 11%
PDB header:protein transport/hydrolase
Chain: D: PDB Molecule:protein tolb;
PDBTitle: structure of tolb in complex with a peptide of the colicin2 e9 t-domain

Phyre2

PDB 2f4m chain A domain 1

Region: 1209 - 1242
Aligned: 34
Modelled: 34
Confidence: 21.0%
Identity: 26%
Fold: Cysteine proteinases
Superfamily: Cysteine proteinases
Family: Transglutaminase core

Phyre2

PDB 3esw chain A

Region: 1209 - 1242
Aligned: 33
Modelled: 34
Confidence: 20.8%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:peptide-n(4)-(n-acetyl-beta-glucosaminyl)asparagine
PDBTitle: complex of yeast pngase with glcnac2-iac.

Phyre2

PDB 1ssk chain A

Region: 1347 - 1410
Aligned: 53
Modelled: 64
Confidence: 20.3%
Identity: 21%
Fold: Coronavirus RNA-binding domain
Superfamily: Coronavirus RNA-binding domain
Family: Coronavirus RNA-binding domain

Phyre2

PDB 3msw chain A

Region: 926 - 995
Aligned: 46
Modelled: 54
Confidence: 20.3%
Identity: 20%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a protein with unknown function (bf3112) from2 bacteroides fragilis nctc 9343 at 1.90 a resolution

Phyre2

PDB 1j5q chain B

Region: 1189 - 1246
Aligned: 50
Modelled: 58
Confidence: 20.0%
Identity: 28%
PDB header:viral protein
Chain: B: PDB Molecule:major capsid protein;
PDBTitle: the structure and evolution of the major capsid protein of a large,2 lipid-containing, dna virus.

Phyre2

PDB 2j43 chain A domain 1

Region: 1243 - 1299
Aligned: 56
Modelled: 57
Confidence: 17.2%
Identity: 16%
Fold: Prealbumin-like
Superfamily: Starch-binding domain-like
Family: PUD-like

Phyre2

PDB 2j44 chain A domain 1

Region: 1243 - 1299
Aligned: 55
Modelled: 57
Confidence: 17.2%
Identity: 15%
Fold: Prealbumin-like
Superfamily: Starch-binding domain-like
Family: PUD-like

Phyre2

PDB 1ei5 chain A domain 1

Region: 1191 - 1209
Aligned: 19
Modelled: 19
Confidence: 15.5%
Identity: 32%
Fold: Streptavidin-like
Superfamily: D-aminopeptidase, middle and C-terminal domains
Family: D-aminopeptidase, middle and C-terminal domains

Phyre2

PDB 3k8h chain A

Region: 1314 - 1362
Aligned: 37
Modelled: 49
Confidence: 15.5%
Identity: 24%
PDB header:membrane protein
Chain: A: PDB Molecule:30klp;
PDBTitle: structure of crystal form i of tp0453

Phyre2

Detailed template information

#	Template	Alignment Coverage	3D Model	Confidence	% i.d.	Template Information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	S	G	K	P	A	A	R	Q	G	D	M	T	Q	Y	G	G	S	I	V	Q	G	S	A	G	V	R	I	G	A	P	T	G	V	A	C	S	V	C	P	G	G	V	T	S	G	H	P	V	N	P	L	L	G	A	K	V	L	P	G
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?		?	?	?	?	?			?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	E	T	D	I	A	L	P	G	P	L	P	F	I	L	S	R	T	Y	S	S	Y	R	T	K	T	P	A	P	V	G	S	L	G	P	G	W	K	M	P	A	D	I	R	L	Q	L	R	D	N	T	L	I	L	S	D	N	G	G	R	S
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	L	Y	F	E	H	L	F	P	G	E	D	G	Y	S	R	S	E	S	L	W	L	V	R	G	G	V	A	K	L	D	E	G	H	R	L	A	A	L	W	Q	A	L	P	E	E	L	R	L	S	P	H	R	Y	L	A	T	N	S	P	Q
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	G	P	W	W	L	L	G	W	C	E	R	V	P	E	A	D	E	V	L	P	A	P	L	P	P	Y	R	V	L	T	G	L	V	D	R	F	G	R	T	Q	T	F	H	R	E	A	A	G	E	F	S	G	E	I	T	G	V	T	D	G
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	A	W	R	H	F	R	L	V	L	T	T	Q	A	Q	R	A	E	E	A	R	Q	Q	A	I	S	G	G	T	E	P	S	A	F	P	D	T	L	P	G	Y	T	E	Y	G	R	D	N	G	I	R	L	S	A	V	W	L	T	H	D	P
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence	E	Y	P	E	N	L	P	A	A	P	L	V	R	Y	G	W	T	P	R	G	E	L	A	V	V	Y	D	R	S	G	K	Q	V	R	S	F	T	Y	D	D	K	Y	R	G	R	M	V	A	H	R	H	T	G	R	P	E	I	R	Y	R
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	Y	D	S	D	G	R	V	T	E	Q	L	N	P	A	G	L	S	Y	T	Y	Q	Y	E	K	D	R	I	T	I	T	D	S	L	D	R	R	E	V	L	H	T	Q	G	E	A	G	L	K	R	V	V	K	K	E	H	A	D	G	S	V
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence	T	Q	S	Q	F	D	A	V	G	R	L	R	A	Q	T	D	A	A	G	R	T	T	E	Y	S	P	D	V	V	T	G	L	I	T	R	I	T	T	P	D	G	R	A	S	A	F	Y	Y	N	H	H	N	Q	L	T	S	A	T	G	P
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence	D	G	L	E	L	R	R	E	Y	D	E	L	G	R	L	I	Q	E	T	A	P	D	G	D	I	T	R	Y	R	Y	D	N	P	H	S	D	L	P	C	A	T	E	D	A	T	G	S	R	K	T	M	T	W	S	R	Y	G	Q	L	L
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence	S	F	T	D	C	S	G	Y	V	T	R	Y	D	H	D	R	F	G	Q	M	T	A	V	H	R	E	E	G	L	S	Q	Y	R	A	Y	D	S	R	G	Q	L	I	A	V	K	D	T	Q	G	H	E	T	R	Y	E	Y	N	I	A	G
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence	D	L	T	A	V	I	A	P	D	G	S	R	N	G	T	Q	Y	D	A	W	G	K	A	V	R	T	T	Q	G	G	L	T	R	S	M	E	Y	D	A	A	G	R	V	I	R	L	T	S	E	N	G	S	H	T	T	F	R	Y	D	V
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence	L	D	R	L	I	Q	E	T	G	F	D	G	R	T	Q	R	Y	H	H	D	L	T	G	K	L	I	R	S	E	D	E	G	L	V	T	H	W	H	Y	D	E	A	D	R	L	T	H	R	T	V	K	G	E	T	A	E	R	W	Q	Y
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Sequence	D	E	R	G	W	L	T	D	I	S	H	I	S	E	G	H	R	V	A	V	H	Y	R	Y	D	E	K	G	R	L	T	G	E	R	Q	T	V	H	H	P	Q	T	E	A	L	L	W	Q	H	E	T	R	H	A	Y	N	A	Q	G	L
Secondary structure
SS confidence
Disorder												?																								?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	A	N	R	C	I	P	D	S	L	P	A	V	E	W	L	T	Y	G	S	G	Y	L	A	G	M	K	L	G	D	T	P	L	V	E	Y	T	R	D	R	L	H	R	E	T	L	R	S	F	G	R	Y	E	L	T	T	A	Y	T	P	A
Secondary structure
SS confidence
Disorder							?
Disorder confidence

	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900
Sequence	G	Q	L	Q	S	Q	H	L	N	S	L	L	S	D	R	D	Y	T	W	N	D	N	G	E	L	I	R	I	S	S	P	R	Q	T	R	S	Y	S	Y	S	T	T	G	R	L	T	G	V	H	T	T	A	A	N	L	D	I	R	I	P
Secondary structure
SS confidence
Disorder											?																				?																				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960
Sequence	Y	A	T	D	P	A	G	N	R	L	P	D	P	E	L	H	P	D	S	T	L	S	M	W	P	D	N	R	I	A	R	D	A	H	Y	L	Y	R	Y	D	R	H	G	R	L	T	E	K	T	D	L	I	P	E	G	V	I	R	T	D
Secondary structure
SS confidence
Disorder																																																			?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020
Sequence	D	E	R	T	H	R	Y	H	Y	D	S	Q	H	R	L	V	H	Y	T	R	T	Q	Y	E	E	P	L	V	E	S	R	Y	L	Y	D	P	L	G	R	R	V	A	K	R	V	W	R	R	E	R	D	L	T	G	W	M	S	L	S	R
Secondary structure
SS confidence
Disorder																					?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080
Sequence	K	P	Q	V	T	W	Y	G	W	D	G	D	R	L	T	T	I	Q	N	D	R	S	R	I	Q	T	I	Y	Q	P	G	S	F	T	P	L	I	R	V	E	T	A	T	G	E	L	A	K	T	Q	R	R	S	L	A	D	A	L	Q	Q
Secondary structure
SS confidence
Disorder
Disorder confidence

	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140
Sequence	S	G	G	E	D	G	G	S	V	V	F	P	P	V	L	V	Q	M	L	D	R	L	E	S	E	I	L	A	D	R	V	S	E	E	S	R	R	W	L	A	S	C	G	L	T	V	E	Q	M	Q	N	Q	M	D	P	V	Y	T	P	A
Secondary structure
SS confidence
Disorder																																																		?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200
Sequence	R	K	I	H	L	Y	H	C	D	H	R	G	L	P	L	A	L	I	S	T	E	G	A	T	A	W	C	A	E	Y	D	E	W	G	N	L	L	N	E	E	N	P	H	Q	L	Q	Q	L	I	R	L	P	G	Q	Q	Y	D	E	E	S
Secondary structure
SS confidence
Disorder																																							?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260
Sequence	G	L	Y	Y	N	R	H	R	Y	Y	D	P	L	Q	G	R	Y	I	T	Q	D	P	I	G	L	K	G	G	W	N	L	Y	G	Y	Q	L	N	P	I	S	D	I	D	P	L	G	L	S	M	W	E	D	A	K	S	G	A	C	T	N
Secondary structure
SS confidence
Disorder																																																				?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320
Sequence	G	L	C	G	T	L	S	A	M	I	G	P	D	K	F	D	S	I	D	S	T	A	Y	D	A	L	N	K	I	N	S	Q	S	I	C	E	D	K	E	F	A	G	L	I	C	K	D	N	S	G	R	Y	F	S	T	A	P	N	R	G
Secondary structure
SS confidence
Disorder								?	?																			?			?	?	?		?						?			?		?	?		?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.	.	.	.	.	1340	.	.	.	.	.	.	.	.	.	1350	.	.	.	.	.	.	.	.	.	1360	.	.	.	.	.	.	.	.	.	1370	.	.	.	.	.	.	.	.	.	1380
Sequence	E	R	K	G	S	Y	P	F	N	S	P	C	P	N	G	T	E	K	V	S	A	Y	H	T	H	G	A	D	S	H	G	E	Y	W	D	E	I	F	S	G	K	D	E	K	I	V	K	S	K	D	N	N	I	K	S	F	Y	L	G	T
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?					?	?										?	?		?	?	?	?	?	?			?	?				?							?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	1390	.	.	.	.	.	.	.	.	.	1400	.	.	.	.	.	.	.	.	.	1410	.
Sequence	P	S	G	N	F	K	A	I	D	N	H	G	K	E	I	T	N	R	K	G	L	P	N	V	C	R	V	H	G	N	M
Secondary structure
SS confidence
Disorder			?																						?	?	?	?	?	?	?
Disorder confidence