Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	V	R	N	I	F	A	D	E	S	H	D	I	Y	T	V	R	T	H	A	D	G	P	D	G	E	L	P	L	T	A	E	M	L	I	N	R	P	S	G	D	L	F	G	M	T	M	N	A	G	M	G	W	S	P	D	E	L	D
Secondary structure
SS confidence
Disorder		?	?					?				?	?						?	?	?	?	?	?	?	?	?	?							?							?														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	D	G	I	L	L	L	S	T	L	G	G	L	R	G	A	D	G	K	P	V	A	L	A	L	H	Q	G	H	Y	E	L	D	I	Q	M	K	A	A	A	E	V	I	K	A	N	H	A	L	P	Y	A	V	Y	V	S	D	P	C	D
Secondary structure
SS confidence
Disorder																	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	R	T	Q	G	T	T	G	M	F	D	S	L	P	Y	R	N	D	A	S	M	V	M	R	R	L	I	R	S	L	P	D	A	K	A	V	I	G	V	A	S	C	D	K	G	L	P	A	T	M	M	A	L	A	A	Q	H	N	I	A
Secondary structure
SS confidence
Disorder					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	V	L	V	P	G	G	A	T	L	P	A	K	D	G	E	D	N	G	K	V	Q	T	I	G	A	R	F	A	N	G	E	L	S	L	Q	D	A	R	R	A	G	C	K	A	C	A	S	S	G	G	G	C	Q	F	L	G	T	A	G
Secondary structure
SS confidence
Disorder														?	?	?	?	?													?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	S	Q	V	V	A	E	G	L	G	L	A	I	P	H	S	A	L	A	P	S	G	E	P	V	W	R	E	I	A	R	A	S	A	R	A	A	L	N	L	S	Q	K	G	I	T	T	R	E	I	L	T	D	K	A	I	E	N	A	M
Secondary structure
SS confidence
Disorder																				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		T	V	H	A	A	F	G	G	S	T	N	L	L	L	H	I	P	A	I	A	H	Q	A	G	C	H	I	P	T	V	D	D	W	I	R	I	N	K	R	V	P	R	L	V	S	V	L	P	N	G	P	V	Y	H	P	T	V	N	A	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		M	A	G	G	V	P	E	V	M	L	H	L	R	S	L	G	L	L	H	E	D	V	M	T	V	T	G	S	T	L	K	E	N	L	D	W	W	E	H	S	E	R	R	Q	R	F	K	Q	L	L	L	D	Q	E	Q	I	N	A	D	E
Secondary structure
SS confidence
Disorder																																										?					?	?		?		?	?	?	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		V	I	M	S	P	Q	Q	A	K	A	R	G	L	T	S	T	I	T	F	P	V	G	N	I	A	P	E	G	S	V	I	K	S	T	A	I	D	P	S	M	I	D	E	Q	G	I	Y	Y	H	K	G	V	A	K	V	Y	L	S	E	K
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?		?																						?					?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		S	A	I	Y	D	I	K	H	D	K	I	K	A	G	D	I	L	V	I	I	G	V	G	P	S	G	T	G	M	E	E	T	Y	Q	V	T	S	A	L	K	H	L	S	Y	G	K	H	V	S	L	I	T	D	A	R	F	S	G	V	S
Secondary structure
SS confidence
Disorder									?		?	?																						?	?	?	?					?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		T	G	A	C	I	G	H	V	G	P	E	A	L	A	G	G	P	I	G	K	L	R	T	G	D	L	I	E	I	K	I	D	C	R	E	L	H	G	E	V	N	F	L	G	T	R	S	D	E	Q	L	P	S	Q	E	E	A	T	A	I
Secondary structure
SS confidence
Disorder																																										?	?	?	?	?	?	?										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.
Sequence		L	N	A	R	P	S	H	Q	D	L	L	P	D	P	E	L	P	D	D	T	R	L	W	A	M	L	Q	A	V	S	G	G	T	W	T	G	C	I	Y	D	V	N	K	I	G	A	A	L	R	D	F	M	N	K	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?																		?																							?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gp4 chain A Region: 104 - 640 Aligned: 470 Modelled: 504 Confidence: 100.0% Identity: 28% PDB header:lyase Chain: A: PDB Molecule:6-phosphogluconate dehydratase; PDBTitle: structure of [fes]cluster-free apo form of 6-phosphogluconate2 dehydratase from shewanella oneidensis Phyre2 PDB 2gp4 chain A domain 2 Region: 87 - 426 Aligned: 306 Modelled: 318 Confidence: 100.0% Identity: 28% Fold: IlvD/EDD N-terminal domain-like Superfamily: IlvD/EDD N-terminal domain-like Family: lvD/EDD N-terminal domain-like Phyre2 PDB 2gp4 chain A domain 1 Region: 436 - 640 Aligned: 179 Modelled: 205 Confidence: 100.0% Identity: 26% Fold: The "swivelling" beta/beta/alpha domain Superfamily: LeuD/IlvD-like Family: IlvD/EDD C-terminal domain-like Phyre2 PDB 2pcn chain A Region: 452 - 536 Aligned: 78 Modelled: 77 Confidence: 76.7% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:s-adenosylmethionine:2-demethylmenaquinone PDBTitle: crystal structure of s-adenosylmethionine: 2-dimethylmenaquinone2 methyltransferase (gk_1813) from geobacillus kaustophilus hta426 Phyre2 PDB 1zym chain A domain 2 Region: 470 - 605 Aligned: 106 Modelled: 136 Confidence: 73.8% Identity: 20% Fold: The "swivelling" beta/beta/alpha domain Superfamily: Phosphohistidine domain Family: N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system Phyre2 PDB 1ujv chain A Region: 503 - 610 Aligned: 82 Modelled: 108 Confidence: 66.9% Identity: 30% Fold: PDZ domain-like Superfamily: PDZ domain-like Family: PDZ domain Phyre2 PDB 2jv2 chain A Region: 561 - 580 Aligned: 20 Modelled: 20 Confidence: 60.6% Identity: 45% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein ph1500; PDBTitle: solution structure of the n-terminal domain of ph1500 Phyre2 PDB 1fjc chain A Region: 464 - 508 Aligned: 45 Modelled: 45 Confidence: 46.0% Identity: 27% Fold: Ferredoxin-like Superfamily: RNA-binding domain, RBD Family: Canonical RBD Phyre2 PDB 1od5 chain A domain 1 Region: 436 - 499 Aligned: 57 Modelled: 64 Confidence: 45.2% Identity: 25% Fold: Double-stranded beta-helix Superfamily: RmlC-like cupins Family: Germin/Seed storage 7S protein Phyre2 PDB 1q5x chain A Region: 452 - 573 Aligned: 118 Modelled: 121 Confidence: 45.0% Identity: 16% Fold: The "swivelling" beta/beta/alpha domain Superfamily: RraA-like Family: RraA-like Phyre2 PDB 1dm9 chain A Region: 561 - 580 Aligned: 20 Modelled: 20 Confidence: 42.6% Identity: 10% Fold: Alpha-L RNA-binding motif Superfamily: Alpha-L RNA-binding motif Family: Heat shock protein 15 kD Phyre2 PDB 1dm9 chain A Region: 561 - 580 Aligned: 20 Modelled: 20 Confidence: 42.6% Identity: 10% PDB header:structural genomics Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka PDBTitle: heat shock protein 15 kd Phyre2 PDB 1pl8 chain A domain 1 Region: 482 - 506 Aligned: 24 Modelled: 25 Confidence: 41.4% Identity: 21% Fold: GroES-like Superfamily: GroES-like Family: Alcohol dehydrogenase-like, N-terminal domain Phyre2 PDB 3soe chain A Region: 511 - 603 Aligned: 67 Modelled: 93 Confidence: 41.0% Identity: 21% PDB header:signaling protein Chain: A: PDB Molecule:membrane-associated guanylate kinase, ww and pdz domain- PDBTitle: crystal structure of the 3rd pdz domain of the human membrane-2 associated guanylate kinase, ww and pdz domain-containing protein 33 (magi3) Phyre2 PDB 2npt chain A domain 1 Region: 562 - 602 Aligned: 19 Modelled: 19 Confidence: 40.0% Identity: 53% Fold: beta-Grasp (ubiquitin-like) Superfamily: CAD & PB1 domains Family: PB1 domain Phyre2 PDB 1rk8 chain A Region: 464 - 506 Aligned: 43 Modelled: 43 Confidence: 36.5% Identity: 21% Fold: Ferredoxin-like Superfamily: RNA-binding domain, RBD Family: Canonical RBD Phyre2 PDB 1wi0 chain A Region: 562 - 602 Aligned: 19 Modelled: 19 Confidence: 36.3% Identity: 53% Fold: beta-Grasp (ubiquitin-like) Superfamily: CAD & PB1 domains Family: PB1 domain Phyre2 PDB 1rkj chain A Region: 474 - 506 Aligned: 33 Modelled: 33 Confidence: 35.9% Identity: 21% PDB header:transcription/rna Chain: A: PDB Molecule:nucleolin; PDBTitle: solution structure of the complex formed by the two n-2 terminal rna-binding domains of nucleolin and a pre-rrna3 target Phyre2 PDB 1r31 chain A domain 1 Region: 232 - 249 Aligned: 17 Modelled: 18 Confidence: 33.8% Identity: 29% Fold: Ferredoxin-like Superfamily: NAD-binding domain of HMG-CoA reductase Family: NAD-binding domain of HMG-CoA reductase Phyre2 PDB 2k8i chain A Region: 563 - 599 Aligned: 33 Modelled: 37 Confidence: 33.5% Identity: 18% PDB header:isomerase Chain: A: PDB Molecule:peptidyl-prolyl cis-trans isomerase; PDBTitle: solution structure of e.coli slyd Phyre2 1 c2gp4A_ 2 d2gp4a2 3 d2gp4a1 4 c2pcnA_ 5 d1zyma2 6 d1ujva_ 7 c2jv2A_ 8 d1fjca_ 9 d1od5a1 10 d1q5xa_ 11 d1dm9a_ 12 c1dm9A_ 13 d1pl8a1 14 c3soeA_ 15 d2npta1 16 d1rk8a_ 17 d1wi0a_ 18 c1rkjA_ 19 d1r31a1 20 c2k8iA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99