Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP23305
DateThu Jan 5 11:39:21 GMT 2012
Unique Job ID78cdd04a10cba690

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3e98B_
Top template information
PDB header:unknown function
Chain: B: PDB Molecule:gaf domain of unknown function;
PDBTitle: crystal structure of a gaf domain containing protein that belongs to2 pfam duf484 family (pa5279) from pseudomonas aeruginosa at 2.43 a3 resolution
Confidence and coverage
Confidence:100.0% Coverage: 73%
171 residues ( 73% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVPHPVRGTVSLVEWHMAR
Secondary structure 
























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Disorder  ???????????????


























????


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   .........70.........80.........90.........100.........110.........120
Sequence  ARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSLDDMLMRFHRWARDLGLAG
Secondary structure 







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   .........130.........140.........150.........160.........170.........180
Sequence  ASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQHYLGPLNGPELLVVLPEAKA
Secondary structure 































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Disorder 








????????





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   .........190.........200.........210.........220.........230.....
Sequence  VGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLHEIALMLPELLERWIERV
Secondary structure 


















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Disorder 























??????




















????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3e98 chain B

3D model

Region: 49 - 231
Aligned: 171
Modelled: 171
Confidence: 100.0%
Identity: 27%
PDB header:unknown function
Chain: B: PDB Molecule:gaf domain of unknown function;
PDBTitle: crystal structure of a gaf domain containing protein that belongs to2 pfam duf484 family (pa5279) from pseudomonas aeruginosa at 2.43 a3 resolution

Phyre2

PDB 3p01 chain C

3D model

Region: 62 - 230
Aligned: 157
Modelled: 169
Confidence: 99.0%
Identity: 13%
PDB header:signaling protein
Chain: C: PDB Molecule:two-component response regulator;
PDBTitle: crystal structure of two-component response regulator from nostoc sp.2 pcc 7120

Phyre2

PDB 2vea chain A domain 1

3D model

Region: 86 - 230
Aligned: 144
Modelled: 145
Confidence: 99.0%
Identity: 10%
Fold: Profilin-like
Superfamily: GAF domain-like
Family: GAF domain

Phyre2

PDB 3p01 chain A

3D model

Region: 63 - 231
Aligned: 164
Modelled: 169
Confidence: 99.0%
Identity: 13%
PDB header:signaling protein
Chain: A: PDB Molecule:two-component response regulator;
PDBTitle: crystal structure of two-component response regulator from nostoc sp.2 pcc 7120

Phyre2

PDB 3mmh chain A

3D model

Region: 83 - 230
Aligned: 146
Modelled: 148
Confidence: 98.9%
Identity: 11%
PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine-r-sulfoxide reductase;
PDBTitle: x-ray structure of free methionine-r-sulfoxide reductase from2 neisseria meningitidis in complex with its substrate

Phyre2

PDB 3ci6 chain B

3D model

Region: 82 - 231
Aligned: 148
Modelled: 148
Confidence: 98.9%
Identity: 15%
PDB header:transferase
Chain: B: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase;
PDBTitle: crystal structure of the gaf domain from acinetobacter2 phosphoenolpyruvate-protein phosphotransferase

Phyre2

PDB 1vhm chain B

3D model

Region: 81 - 230
Aligned: 148
Modelled: 150
Confidence: 98.9%
Identity: 13%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:protein yebr;
PDBTitle: crystal structure of an hypothetical protein

Phyre2

PDB 1vhm chain A

3D model

Region: 83 - 230
Aligned: 146
Modelled: 148
Confidence: 98.9%
Identity: 13%
Fold: Profilin-like
Superfamily: GAF domain-like
Family: GAF domain

Phyre2

PDB 2o9c chain A domain 1

3D model

Region: 87 - 230
Aligned: 142
Modelled: 144
Confidence: 98.9%
Identity: 14%
Fold: Profilin-like
Superfamily: GAF domain-like
Family: GAF domain

Phyre2

PDB 3ksi chain A

3D model

Region: 87 - 228
Aligned: 140
Modelled: 142
Confidence: 98.8%
Identity: 9%
PDB header:oxidoreductase
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: structure of frmsr of staphylococcus aureus (complex with 2-propanol)

Phyre2

PDB 3trc chain A

3D model

Region: 83 - 231
Aligned: 148
Modelled: 147
Confidence: 98.8%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase;
PDBTitle: structure of the gaf domain from a phosphoenolpyruvate-protein2 phosphotransferase (ptsp) from coxiella burnetii

Phyre2

PDB 2ool chain A domain 1

3D model

Region: 80 - 230
Aligned: 149
Modelled: 150
Confidence: 98.8%
Identity: 15%
Fold: Profilin-like
Superfamily: GAF domain-like
Family: GAF domain

Phyre2

PDB 3k2n chain B

3D model

Region: 82 - 230
Aligned: 147
Modelled: 149
Confidence: 98.7%
Identity: 12%
PDB header:transcription regulator
Chain: B: PDB Molecule:sigma-54-dependent transcriptional regulator;
PDBTitle: the crystal structure of sigma-54-dependent transcriptional2 regulator domain from chlorobium tepidum tls

Phyre2

PDB 3o5y chain A

3D model

Region: 100 - 230
Aligned: 130
Modelled: 130
Confidence: 98.6%
Identity: 14%
PDB header:transcription regulator
Chain: A: PDB Molecule:sensor protein;
PDBTitle: the crystal structure of the gaf domain of a two-component sensor2 histidine kinase from bacillus halodurans to 2.45a

Phyre2

PDB 3hcy chain B

3D model

Region: 99 - 230
Aligned: 128
Modelled: 132
Confidence: 98.6%
Identity: 10%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative two-component sensor histidine kinase protein;
PDBTitle: the crystal structure of the domain of putative two-component sensor2 histidine kinase protein from sinorhizobium meliloti 1021

Phyre2

PDB 1mc0 chain A

3D model

Region: 55 - 230
Aligned: 176
Modelled: 176
Confidence: 98.5%
Identity: 9%
PDB header:hydrolase
Chain: A: PDB Molecule:3',5'-cyclic nucleotide phosphodiesterase 2a;
PDBTitle: regulatory segment of mouse 3',5'-cyclic nucleotide phosphodiesterase2 2a, containing the gaf a and gaf b domains

Phyre2

PDB 3oov chain A

3D model

Region: 91 - 230
Aligned: 140
Modelled: 140
Confidence: 98.4%
Identity: 12%
PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein, putative;
PDBTitle: crystal structure of a methyl-accepting chemotaxis protein, residues2 122 to 287

Phyre2

PDB 3e0y chain A

3D model

Region: 89 - 231
Aligned: 136
Modelled: 143
Confidence: 98.4%
Identity: 10%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved domain protein;
PDBTitle: the crystal structure of a conserved domain from a protein of2 geobacter sulfurreducens pca

Phyre2

PDB 1ykd chain B

3D model

Region: 45 - 230
Aligned: 185
Modelled: 186
Confidence: 98.3%
Identity: 13%
PDB header:lyase
Chain: B: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of the tandem gaf domains from a cyanobacterial2 adenylyl cyclase: novel modes of ligand-binding and dimerization

Phyre2

PDB 2ool chain A

3D model

Region: 82 - 231
Aligned: 149
Modelled: 149
Confidence: 98.3%
Identity: 11%
PDB header:signaling protein
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of the chromophore-binding domain of an unusual2 bacteriophytochrome rpbphp3 from r. palustris

Phyre2

PDB 1ube chain A domain 2

3D model

Region: 18 - 33
Aligned: 16
Modelled: 16
Confidence: 55.0%
Identity: 13%
Fold: Anti-LPS factor/recA domain
Superfamily: RecA protein, C-terminal domain
Family: RecA protein, C-terminal domain

Phyre2

PDB 1mo6 chain A domain 2

3D model

Region: 18 - 33
Aligned: 16
Modelled: 16
Confidence: 54.2%
Identity: 13%
Fold: Anti-LPS factor/recA domain
Superfamily: RecA protein, C-terminal domain
Family: RecA protein, C-terminal domain

Phyre2

PDB 1u94 chain A domain 2

3D model

Region: 18 - 33
Aligned: 16
Modelled: 16
Confidence: 52.1%
Identity: 25%
Fold: Anti-LPS factor/recA domain
Superfamily: RecA protein, C-terminal domain
Family: RecA protein, C-terminal domain

Phyre2

PDB 2v0e chain A domain 1

3D model

Region: 18 - 35
Aligned: 18
Modelled: 18
Confidence: 50.1%
Identity: 17%
Fold: GYF/BRK domain-like
Superfamily: BRK domain-like
Family: BRK domain-like

Phyre2
1

c3e98B_
2

c3p01C_
3

d2veaa1
4

c3p01A_
5

c3mmhA_
6

c3ci6B_
7

c1vhmB_
8

d1vhma_
9

d2o9ca1
10

c3ksiA_
11

c3trcA_
12

d2oola1
13

c3k2nB_
14

c3o5yA_
15

c3hcyB_
16

c1mc0A_
17

c3oovA_
18

c3e0yA_
19

c1ykdB_
20

c2oolA_
21



22



23



24



25



26



27



28



29



30



31



32



33



34



35



36



37



38



39



40



41



42



43

d1ubea2
44

d1mo6a2
45

d1u94a2
46

d2v0ea1
47



48



49



50



51



52



53



54



55



56



57



58



59



60



61



62



63



64



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66



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68



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72



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82



83



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85



86



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89



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91



92



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94



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98



99






Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3e98B_



100.0 27 PDB header:unknown function
Chain: B: PDB Molecule:gaf domain of unknown function;
PDBTitle: crystal structure of a gaf domain containing protein that belongs to2 pfam duf484 family (pa5279) from pseudomonas aeruginosa at 2.43 a3 resolution
2c3p01C_



99.0 13 PDB header:signaling protein
Chain: C: PDB Molecule:two-component response regulator;
PDBTitle: crystal structure of two-component response regulator from nostoc sp.2 pcc 7120
3d2veaa1



99.0 10 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
4c3p01A_



99.0 13 PDB header:signaling protein
Chain: A: PDB Molecule:two-component response regulator;
PDBTitle: crystal structure of two-component response regulator from nostoc sp.2 pcc 7120
5c3mmhA_



98.9 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine-r-sulfoxide reductase;
PDBTitle: x-ray structure of free methionine-r-sulfoxide reductase from2 neisseria meningitidis in complex with its substrate
6c3ci6B_



98.9 15 PDB header:transferase
Chain: B: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase;
PDBTitle: crystal structure of the gaf domain from acinetobacter2 phosphoenolpyruvate-protein phosphotransferase
7c1vhmB_



98.9 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:protein yebr;
PDBTitle: crystal structure of an hypothetical protein
8d1vhma_



98.9 13 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
9d2o9ca1



98.9 14 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
10c3ksiA_



98.8 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative uncharacterized protein;
PDBTitle: structure of frmsr of staphylococcus aureus (complex with 2-propanol)
11c3trcA_



98.8 13 PDB header:transferase
Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase;
PDBTitle: structure of the gaf domain from a phosphoenolpyruvate-protein2 phosphotransferase (ptsp) from coxiella burnetii
12d2oola1



98.8 15 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
13c3k2nB_



98.7 12 PDB header:transcription regulator
Chain: B: PDB Molecule:sigma-54-dependent transcriptional regulator;
PDBTitle: the crystal structure of sigma-54-dependent transcriptional2 regulator domain from chlorobium tepidum tls
14c3o5yA_



98.6 14 PDB header:transcription regulator
Chain: A: PDB Molecule:sensor protein;
PDBTitle: the crystal structure of the gaf domain of a two-component sensor2 histidine kinase from bacillus halodurans to 2.45a
15c3hcyB_



98.6 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative two-component sensor histidine kinase protein;
PDBTitle: the crystal structure of the domain of putative two-component sensor2 histidine kinase protein from sinorhizobium meliloti 1021
16c1mc0A_



98.5 9 PDB header:hydrolase
Chain: A: PDB Molecule:3',5'-cyclic nucleotide phosphodiesterase 2a;
PDBTitle: regulatory segment of mouse 3',5'-cyclic nucleotide phosphodiesterase2 2a, containing the gaf a and gaf b domains
17c3oovA_



98.4 12 PDB header:signaling protein
Chain: A: PDB Molecule:methyl-accepting chemotaxis protein, putative;
PDBTitle: crystal structure of a methyl-accepting chemotaxis protein, residues2 122 to 287
18c3e0yA_



98.4 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved domain protein;
PDBTitle: the crystal structure of a conserved domain from a protein of2 geobacter sulfurreducens pca
19c1ykdB_



98.3 13 PDB header:lyase
Chain: B: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of the tandem gaf domains from a cyanobacterial2 adenylyl cyclase: novel modes of ligand-binding and dimerization
20c2oolA_



98.3 11 PDB header:signaling protein
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of the chromophore-binding domain of an unusual2 bacteriophytochrome rpbphp3 from r. palustris
21d2k2na1



not modelled 98.3 18 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
22d1f5ma_



not modelled 98.3 11 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
23d3c2wa1



not modelled 98.3 11 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
24c3eeaB_



not modelled 98.2 12 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:gaf domain/hd domain protein;
PDBTitle: the crystal structure of the gaf domain/hd domain protein2 from geobacter sulfurreducens
25c3mf0A_



not modelled 98.2 9 PDB header:hydrolase
Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase;
PDBTitle: crystal structure of pde5a gaf domain (89-518)
26c2lb5A_



not modelled 98.1 14 PDB header:transferase
Chain: A: PDB Molecule:sensor histidine kinase;
PDBTitle: refined structural basis for the photoconversion of a phytochrome to2 the activated far-red light-absorbing form
27c2zmfA_



not modelled 98.1 12 PDB header:hydrolase
Chain: A: PDB Molecule:camp and camp-inhibited cgmp 3',5'-cyclic phosphodiesterase
PDBTitle: crystal structure of the c-terminal gaf domain of human2 phosphodiesterase 10a
28c2o9bA_



not modelled 98.1 11 PDB header:transferase
Chain: A: PDB Molecule:bacteriophytochrome;
PDBTitle: crystal structure of bacteriophytochrome chromophore binding domain
29c2qybA_



not modelled 98.1 14 PDB header:membrane protein
Chain: A: PDB Molecule:membrane protein, putative;
PDBTitle: crystal structure of the gaf domain region of putative membrane2 protein from geobacter sulfurreducens pca
30c2vjwA_



not modelled 98.0 12 PDB header:hydrolase
Chain: A: PDB Molecule:gaf family protein;
PDBTitle: crystal structure of the second gaf domain of devs from2 mycobacterium smegmatis
31c3ibjB_



not modelled 97.9 9 PDB header:hydrolase
Chain: B: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase;
PDBTitle: x-ray structure of pde2a
32c3dbaB_



not modelled 97.9 8 PDB header:hydrolase
Chain: B: PDB Molecule:cone cgmp-specific 3',5'-cyclic phosphodiesterase subunit
PDBTitle: crystal structure of the cgmp-bound gaf a domain from the2 photoreceptor phosphodiesterase 6c
33c2w3gA_



not modelled 97.8 7 PDB header:transferase
Chain: A: PDB Molecule:two component sensor histidine kinase devs (gaf
PDBTitle: air-oxidized structure of the first gaf domain of2 mycobacterium tuberculosis doss
34d1mc0a1



not modelled 97.8 8 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
35c3c2wB_



not modelled 97.7 8 PDB header:signaling protein
Chain: B: PDB Molecule:bacteriophytochrome;
PDBTitle: crystal structure of the photosensory core domain of p.2 aeruginosa bacteriophytochrome pabphp in the pfr state
36c2veaA_



not modelled 97.3 10 PDB header:transferase
Chain: A: PDB Molecule:phytochrome-like protein cph1;
PDBTitle: the complete sensory module of the cyanobacterial2 phytochrome cph1 in the pr-state.
37d1mc0a2



not modelled 97.2 8 Fold:Profilin-like
Superfamily:GAF domain-like
Family:GAF domain
38c2k31A_



not modelled 96.9 7 PDB header:hydrolase
Chain: A: PDB Molecule:phosphodiesterase 5a, cgmp-specific;
PDBTitle: solution structure of cgmp-binding gaf domain of2 phosphodiesterase 5
39c2xssB_



not modelled 95.9 7 PDB header:hydrolase
Chain: B: PDB Molecule:cgmp-specific 3', 5'-cyclic phosphodiesterase;
PDBTitle: crystal structure of gafb from the human phosphodiesterase 5
40c2w1tB_



not modelled 81.4 13 PDB header:transcription
Chain: B: PDB Molecule:stage v sporulation protein t;
PDBTitle: crystal structure of b. subtilis spovt
41c2w1rA_



not modelled 80.1 16 PDB header:transcription
Chain: A: PDB Molecule:stage v sporulation protein t;
PDBTitle: crystal structure of the c-terminal domain of b. subtilis2 spovt
42c2gx5B_



not modelled 65.7 14 PDB header:transcription
Chain: B: PDB Molecule:gtp-sensing transcriptional pleiotropic repressor cody;
PDBTitle: n-terminal gaf domain of transcriptional pleiotropic repressor cody
43d1ubea2



55.0 13 Fold:Anti-LPS factor/recA domain
Superfamily:RecA protein, C-terminal domain
Family:RecA protein, C-terminal domain
44d1mo6a2



54.2 13 Fold:Anti-LPS factor/recA domain
Superfamily:RecA protein, C-terminal domain
Family:RecA protein, C-terminal domain
45d1u94a2



52.1 25 Fold:Anti-LPS factor/recA domain
Superfamily:RecA protein, C-terminal domain
Family:RecA protein, C-terminal domain
46d2v0ea1



50.1 17 Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
47d1xp8a2



not modelled 49.8 19 Fold:Anti-LPS factor/recA domain
Superfamily:RecA protein, C-terminal domain
Family:RecA protein, C-terminal domain
48c2ckaA_



not modelled 48.3 31 PDB header:hydrolase
Chain: A: PDB Molecule:chromodomain-helicase-dna-binding protein 8;
PDBTitle: solution structures of the brk domains of the human chromo2 helicase domain 7 and 8, reveals structural similarity3 with gyf domain suggesting a role in protein interaction
49d2ckaa1



not modelled 48.3 31 Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
50d2pnwa1



not modelled 47.2 11 Fold:Double psi beta-barrel
Superfamily:Barwin-like endoglucanases
Family:MLTA-like
51c1pk1B_



not modelled 46.4 9 PDB header:transcription repression
Chain: B: PDB Molecule:sex comb on midleg cg9495-pa;
PDBTitle: hetero sam domain structure of ph and scm.
52c2avxA_



not modelled 45.9 14 PDB header:transcription
Chain: A: PDB Molecule:regulatory protein sdia;
PDBTitle: solution structure of e coli sdia1-171
53d1l3la2



not modelled 45.5 12 Fold:Profilin-like
Superfamily:Pheromone-binding domain of LuxR-like quorum-sensing transcription factors
Family:Pheromone-binding domain of LuxR-like quorum-sensing transcription factors
54c2ckcA_



not modelled 45.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:chromodomain-helicase-dna-binding protein 7;
PDBTitle: solution structures of the brk domains of the human chromo2 helicase domain 7 and 8, reveals structural similarity3 with gyf domain suggesting a role in protein interaction
55d2ckca1



not modelled 45.0 17 Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
56d1pk3a1



not modelled 42.4 12 Fold:SAM domain-like
Superfamily:SAM/Pointed domain
Family:SAM (sterile alpha motif) domain
57d2g5da1



not modelled 42.1 21 Fold:Double psi beta-barrel
Superfamily:Barwin-like endoglucanases
Family:MLTA-like
58d1i27a_



not modelled 40.9 36 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:"Winged helix" DNA-binding domain
Family:C-terminal domain of the rap74 subunit of TFIIF
59d2dl6a1



not modelled 37.8 31 Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
60c2j5uB_



not modelled 36.6 13 PDB header:cell shape regulation
Chain: B: PDB Molecule:mrec protein;
PDBTitle: mrec lysteria monocytogenes
61c2wpyA_



not modelled 35.3 27 PDB header:transcription
Chain: A: PDB Molecule:general control protein gcn4;
PDBTitle: gcn4 leucine zipper mutant with one vxxnxxx motif2 coordinating chloride
62c3c0rC_



not modelled 35.2 19 PDB header:cell cycle, hydrolase
Chain: C: PDB Molecule:ubiquitin thioesterase otu1;
PDBTitle: structure of ovarian tumor (otu) domain in complex with ubiquitin
63c1dipA_



not modelled 34.3 22 PDB header:acetylation
Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive
PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures
64d2ia7a1



not modelled 33.1 22 Fold:gpW/gp25-like
Superfamily:gpW/gp25-like
Family:gpW/gp25-like
65c3hefB_



not modelled 32.8 31 PDB header:viral protein
Chain: B: PDB Molecule:gene 1 protein;
PDBTitle: crystal structure of the bacteriophage sf6 terminase small2 subunit
66c3pfyA_



not modelled 32.8 35 PDB header:hydrolase
Chain: A: PDB Molecule:otu domain-containing protein 5;
PDBTitle: the catalytic domain of human otud5
67c2k7rA_



not modelled 32.6 33 PDB header:replication
Chain: A: PDB Molecule:primosomal protein dnai;
PDBTitle: n-terminal domain of the bacillus subtilis helicase-loading2 protein dnai
68c3fkhB_



not modelled 31.9 11 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyridoxamine 5'-phosphate oxidase;
PDBTitle: crystal structure of putative pyridoxamine 5'-phosphate oxidase2 (np_601736.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.51 a resolution
69d2ff4a1



not modelled 31.8 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
70d2v0fa1



not modelled 29.9 38 Fold:GYF/BRK domain-like
Superfamily:BRK domain-like
Family:BRK domain-like
71c3eoiB_



not modelled 24.7 46 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:pilm;
PDBTitle: crystal structure of putative protein pilm from escherichia coli b7a
72c1ci6B_



not modelled 24.0 22 PDB header:transcription
Chain: B: PDB Molecule:transcription factor c/ebp beta;
PDBTitle: transcription factor atf4-c/ebp beta bzip heterodimer
73c3iwfA_



not modelled 22.6 3 PDB header:transcription regulator
Chain: A: PDB Molecule:transcription regulator rpir family;
PDBTitle: the crystal structure of the n-terminal domain of a rpir2 transcriptional regulator from staphylococcus epidermidis to 1.4a
74d1gxqa_



not modelled 22.0 14 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
75c1swiB_



not modelled 21.9 27 PDB header:leucine zipper
Chain: B: PDB Molecule:gcn4p1;
PDBTitle: gcn4-leucine zipper core mutant as n16a complexed with2 benzene
76c1rb4A_



not modelled 21.9 27 PDB header:dna binding protein
Chain: A: PDB Molecule:general control protein gcn4;
PDBTitle: antiparallel trimer of gcn4-leucine zipper core mutant as2 n16a tetragonal automatic solution
77d2o3fa1



not modelled 21.6 25 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:Homeodomain-like
Family:RpiR-like
78c2o3fC_



not modelled 21.6 25 PDB header:transcription
Chain: C: PDB Molecule:putative hth-type transcriptional regulator ybbh;
PDBTitle: structural genomics, the crystal structure of the n-2 terminal domain of the putative transcriptional regulator3 ybbh from bacillus subtilis subsp. subtilis str. 168.
79c2yxlA_



not modelled 21.0 27 PDB header:transferase
Chain: A: PDB Molecule:450aa long hypothetical fmu protein;
PDBTitle: crystal structure of ph0851
80c1rb6B_



not modelled 21.0 27 PDB header:dna binding protein
Chain: B: PDB Molecule:general control protein gcn4;
PDBTitle: antiparallel trimer of gcn4-leucine zipper core mutant as2 n16a tetragonal form
81c1rb4B_



not modelled 21.0 27 PDB header:dna binding protein
Chain: B: PDB Molecule:general control protein gcn4;
PDBTitle: antiparallel trimer of gcn4-leucine zipper core mutant as2 n16a tetragonal automatic solution
82c1rb5C_



not modelled 21.0 27 PDB header:dna binding protein
Chain: C: PDB Molecule:general control protein gcn4;
PDBTitle: antiparallel trimer of gcn4-leucine zipper core mutant as2 n16a trigonal form
83c2eanA_



not modelled 20.7 14 PDB header:signaling protein
Chain: A: PDB Molecule:connector enhancer of kinase suppressor of ras 2;
PDBTitle: solution structure of the n-terminal sam-domain of human2 kiaa0902 protein (connector enhancer of kinase suppressor3 of ras 2)
84c2uv0G_



not modelled 20.4 15 PDB header:transcription
Chain: G: PDB Molecule:transcriptional activator protein lasr;
PDBTitle: structure of the p. aeruginosa lasr ligand-binding domain2 bound to its autoinducer
85c1rb5B_



not modelled 20.0 27 PDB header:dna binding protein
Chain: B: PDB Molecule:general control protein gcn4;
PDBTitle: antiparallel trimer of gcn4-leucine zipper core mutant as2 n16a trigonal form
86c1rb6A_



not modelled 20.0 27 PDB header:dna binding protein
Chain: A: PDB Molecule:general control protein gcn4;
PDBTitle: antiparallel trimer of gcn4-leucine zipper core mutant as2 n16a tetragonal form
87c1rb5A_



not modelled 20.0 27 PDB header:dna binding protein
Chain: A: PDB Molecule:general control protein gcn4;
PDBTitle: antiparallel trimer of gcn4-leucine zipper core mutant as2 n16a trigonal form
88c2oqqB_



not modelled 19.9 33 PDB header:transcription
Chain: B: PDB Molecule:transcription factor hy5;
PDBTitle: crystal structure of hy5 leucine zipper homodimer from2 arabidopsis thaliana
89c3m6wA_



not modelled 18.9 33 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine
90d2o34a1



not modelled 18.2 14 Fold:T-fold
Superfamily:ApbE-like
Family:DVU1097-like
91c2wpzA_



not modelled 18.1 23 PDB header:transcription
Chain: A: PDB Molecule:general control protein gcn4;
PDBTitle: gcn4 leucine zipper mutant with two vxxnxxx motifs2 coordinating chloride
92c2nytB_



not modelled 17.9 15 PDB header:hydrolase
Chain: B: PDB Molecule:probable c->u-editing enzyme apobec-2;
PDBTitle: the apobec2 crystal structure and functional implications2 for aid
93c3cp3A_



not modelled 17.6 22 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of conserved protein of unknown function dip18742 from corynebacterium diphtheriae
94c2pywA_



not modelled 17.0 25 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: structure of a. thaliana 5-methylthioribose kinase in complex with adp2 and mtr
95c2wpzB_



not modelled 16.9 23 PDB header:transcription
Chain: B: PDB Molecule:general control protein gcn4;
PDBTitle: gcn4 leucine zipper mutant with two vxxnxxx motifs2 coordinating chloride
96d1pvea_



not modelled 16.8 25 Fold:XPC-binding domain
Superfamily:XPC-binding domain
Family:XPC-binding domain
97d2vkva2



not modelled 16.7 9 Fold:Tetracyclin repressor-like, C-terminal domain
Superfamily:Tetracyclin repressor-like, C-terminal domain
Family:Tetracyclin repressor-like, C-terminal domain
98c2xh3B_



not modelled 16.6 15 PDB header:hydrolase
Chain: B: PDB Molecule:spd1 nuclease;
PDBTitle: extracellular nuclease
99c2nt8A_



not modelled 16.5 17 PDB header:transferase
Chain: A: PDB Molecule:cobalamin adenosyltransferase;
PDBTitle: atp bound at the active site of a pduo type atp:co(i)rrinoid2 adenosyltransferase from lactobacillus reuteri

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0