Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	T	I	D	S	M	N	K	D	T	T	R	L	S	D	G	P	D	W	T	F	D	L	L	D	V	Y	L	A	E	I	D	R	V	A	K	L	Y	R	L	D	T	Y	P	H	Q	I	E	V	I	T	S	E	Q	M	M	D	A	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?		?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	S	V	G	M	P	I	N	Y	P	H	W	S	F	G	K	K	F	I	E	T	E	R	L	Y	K	H	G	Q	Q	G	L	A	Y	E	I	V	I	N	S	N	P	C	I	A	Y	L	M	E	E	N	T	I	T	M	Q	A	L	V	M
Secondary structure
SS confidence
Disorder																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	H	A	C	Y	G	H	N	S	F	F	K	N	N	Y	L	F	R	S	W	T	D	A	S	S	I	V	D	Y	L	I	F	A	R	K	Y	I	T	E	C	E	E	R	Y	G	V	D	E	V	E	R	L	L	D	S	C	H	A	L	M
Secondary structure
SS confidence
Disorder																							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		N	Y	G	V	D	R	Y	K	R	P	Q	K	I	S	L	Q	E	E	K	A	R	Q	K	S	R	E	E	Y	L	Q	S	Q	V	N	M	L	W	R	T	L	P	K	R	E	E	E	K	T	V	A	E	A	R	R	Y	P	S	E	P	Q
Secondary structure
SS confidence
Disorder											?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?										?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	N	L	L	Y	F	M	E	K	N	A	P	L	L	E	S	W	Q	R	E	I	L	R	I	V	R	K	V	S	Q	Y	F	Y	P	Q	K	Q	T	Q	V	M	N	E	G	W	A	T	F	W	H	Y	T	I	L	N	H	L	Y	D	E
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	K	V	T	E	R	F	M	L	E	F	L	H	S	H	T	N	V	V	F	Q	P	P	Y	N	S	P	W	Y	S	G	I	N	P	Y	A	L	G	F	A	M	F	Q	D	I	K	R	I	C	Q	S	P	T	E	E	D	K	Y	W	F
Secondary structure
SS confidence
Disorder		?	?	?																	?			?	?	?	?	?	?	?																					?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		P	D	I	A	G	S	D	W	L	E	T	L	H	F	A	M	R	D	F	K	D	E	S	F	I	S	Q	F	L	S	P	K	V	M	R	D	F	R	F	F	T	V	L	D	D	D	R	H	N	Y	L	E	I	S	A	I	H	N	E	E
Secondary structure
SS confidence
Disorder		?		?	?	?	?	?																																								?	?	?										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	Y	R	E	I	R	N	R	L	S	S	Q	Y	N	L	S	N	L	E	P	N	I	Q	I	W	N	V	D	L	R	G	D	R	S	L	T	L	R	Y	I	P	H	N	R	A	P	L	D	R	G	R	K	E	V	L	K	H	V	H	R
Secondary structure
SS confidence
Disorder																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510
Sequence		L	W	G	F	D	V	M	L	E	Q	Q	N	E	D	G	S	I	E	L	L	E	R	C	P	P	R	M	G	N	L
Secondary structure
SS confidence
Disorder														?		?	?								?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3b7u chain X Region: 281 - 391 Aligned: 85 Modelled: 93 Confidence: 92.2% Identity: 19% PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan Phyre2 PDB 3cia chain A Region: 281 - 379 Aligned: 81 Modelled: 81 Confidence: 89.9% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea Phyre2 PDB 3iuk chain B Region: 283 - 352 Aligned: 63 Modelled: 70 Confidence: 89.7% Identity: 25% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of putative bacterial protein of unknown function2 (duf885, pf05960.1, ) from arthrobacter aurescens tc1, reveals fold3 similar to that of m32 carboxypeptidases Phyre2 PDB 2xpy chain A Region: 281 - 379 Aligned: 81 Modelled: 81 Confidence: 84.1% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae Phyre2 PDB 3o0y chain C Region: 283 - 349 Aligned: 59 Modelled: 67 Confidence: 83.6% Identity: 24% PDB header:lipid binding protein Chain: C: PDB Molecule:lipoprotein; PDBTitle: the crystal structure of the putative lipoprotein from colwellia2 psychrerythraea Phyre2 PDB 3se6 chain A Region: 281 - 503 Aligned: 168 Modelled: 190 Confidence: 79.7% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2; PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2 Phyre2 PDB 3qnf chain A Region: 258 - 379 Aligned: 104 Modelled: 104 Confidence: 65.7% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1 Phyre2 PDB 1z5h chain B Region: 281 - 379 Aligned: 80 Modelled: 81 Confidence: 65.4% Identity: 21% PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum Phyre2 PDB 1yew chain C Region: 285 - 311 Aligned: 23 Modelled: 27 Confidence: 50.4% Identity: 43% PDB header:oxidoreductase, membrane protein Chain: C: PDB Molecule:particulate methane monooxygenase subunit c2; PDBTitle: crystal structure of particulate methane monooxygenase Phyre2 PDB 3mdj chain B Region: 281 - 379 Aligned: 74 Modelled: 81 Confidence: 50.1% Identity: 14% PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor,2 bestatin Phyre2 PDB 1q8c chain A Region: 240 - 279 Aligned: 39 Modelled: 40 Confidence: 35.9% Identity: 23% Fold: NusB-like Superfamily: NusB-like Family: Hypothetical protein MG027 Phyre2 PDB 3b7s chain A domain 3 Region: 281 - 379 Aligned: 81 Modelled: 81 Confidence: 34.3% Identity: 19% Fold: Zincin-like Superfamily: Metalloproteases ("zincins"), catalytic domain Family: Leukotriene A4 hydrolase catalytic domain Phyre2 PDB 3chx chain G Region: 285 - 311 Aligned: 23 Modelled: 27 Confidence: 33.0% Identity: 43% PDB header:membrane protein Chain: G: PDB Molecule:pmoc; PDBTitle: crystal structure of methylosinus trichosporium ob3b2 particulate methane monooxygenase (pmmo) Phyre2 PDB 2xdt chain A Region: 281 - 379 Aligned: 79 Modelled: 81 Confidence: 31.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1 Phyre2 PDB 1wpb chain A Region: 258 - 337 Aligned: 76 Modelled: 80 Confidence: 29.9% Identity: 9% Fold: YfbU-like Superfamily: YfbU-like Family: YfbU-like Phyre2 PDB 2kna chain A Region: 149 - 209 Aligned: 61 Modelled: 61 Confidence: 29.7% Identity: 18% PDB header:apoptosis Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 4; PDBTitle: solution structure of uba domain of xiap Phyre2 PDB 2qff chain A Region: 288 - 336 Aligned: 31 Modelled: 49 Confidence: 28.5% Identity: 19% PDB header:hydrolase inhibitor Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of staphylococcal complement inhibitor Phyre2 PDB 2da4 chain A Region: 2 - 42 Aligned: 38 Modelled: 38 Confidence: 27.8% Identity: 26% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dkfzp686k21156; PDBTitle: solution structure of the homeobox domain of the2 hypothetical protein, dkfzp686k21156 Phyre2 PDB 1ceu chain A Region: 252 - 270 Aligned: 18 Modelled: 19 Confidence: 24.6% Identity: 22% PDB header:viral protein Chain: A: PDB Molecule:protein (hiv-1 regulatory protein n-terminal PDBTitle: nmr structure of the (1-51) n-terminal domain of the hiv-12 regulatory protein Phyre2 PDB 1dl2 chain A Region: 389 - 481 Aligned: 76 Modelled: 93 Confidence: 23.7% Identity: 17% Fold: alpha/alpha toroid Superfamily: Seven-hairpin glycosidases Family: Class I alpha-1;2-mannosidase, catalytic domain Phyre2 1 c3b7uX_ 2 c3ciaA_ 3 c3iukB_ 4 c2xpyA_ 5 c3o0yC_ 6 c3se6A_ 7 c3qnfA_ 8 c1z5hB_ 9 c1yewC_ 10 c3mdjB_ 11 d1q8ca_ 12 d3b7sa3 13 c3chxG_ 14 c2xdtA_ 15 d1wpba_ 16 c2knaA_ 17 c2qffA_ 18 c2da4A_ 19 c1ceuA_ 20 d1dl2a_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3b7uX_ 92.2 19 PDB header:hydrolase Chain: X: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: leukotriene a4 hydrolase complexed with kelatorphan 2 c3ciaA_ 89.9 15 PDB header:hydrolase Chain: A: PDB Molecule:cold-active aminopeptidase; PDBTitle: crystal structure of cold-aminopeptidase from colwellia2 psychrerythraea 3 c3iukB_ 89.7 25 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of putative bacterial protein of unknown function2 (duf885, pf05960.1, ) from arthrobacter aurescens tc1, reveals fold3 similar to that of m32 carboxypeptidases 4 c2xpyA_ 84.1 20 PDB header:hydrolase Chain: A: PDB Molecule:leukotriene a-4 hydrolase; PDBTitle: structure of native leukotriene a4 hydrolase from saccharomyces2 cerevisiae 5 c3o0yC_ 83.6 24 PDB header:lipid binding protein Chain: C: PDB Molecule:lipoprotein; PDBTitle: the crystal structure of the putative lipoprotein from colwellia2 psychrerythraea 6 c3se6A_ 79.7 16 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 2; PDBTitle: crystal structure of the human endoplasmic reticulum aminopeptidase 2 7 c3qnfA_ 65.7 13 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1 8 c1z5hB_ 65.4 21 PDB header:hydrolase Chain: B: PDB Molecule:tricorn protease interacting factor f3; PDBTitle: crystal structures of the tricorn interacting factor f32 from thermoplasma acidophilum 9 c1yewC_ 50.4 43 PDB header:oxidoreductase, membrane protein Chain: C: PDB Molecule:particulate methane monooxygenase subunit c2; PDBTitle: crystal structure of particulate methane monooxygenase 10 c3mdjB_ 50.1 14 PDB header:hydrolase/hydrolase inhibitor Chain: B: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: er aminopeptidase, erap1, bound to the zinc aminopeptidase inhibitor,2 bestatin 11 d1q8ca_ 35.9 23 Fold:NusB-like Superfamily:NusB-like Family:Hypothetical protein MG027 12 d3b7sa3 34.3 19 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Leukotriene A4 hydrolase catalytic domain 13 c3chxG_ 33.0 43 PDB header:membrane protein Chain: G: PDB Molecule:pmoc; PDBTitle: crystal structure of methylosinus trichosporium ob3b2 particulate methane monooxygenase (pmmo) 14 c2xdtA_ 31.0 18 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1; PDBTitle: crystal structure of the soluble domain of human2 endoplasmic reticulum aminopeptidase 1 erap1 15 d1wpba_ 29.9 9 Fold:YfbU-like Superfamily:YfbU-like Family:YfbU-like 16 c2knaA_ 29.7 18 PDB header:apoptosis Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 4; PDBTitle: solution structure of uba domain of xiap 17 c2qffA_ 28.5 19 PDB header:hydrolase inhibitor Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of staphylococcal complement inhibitor 18 c2da4A_ 27.8 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein dkfzp686k21156; PDBTitle: solution structure of the homeobox domain of the2 hypothetical protein, dkfzp686k21156 19 c1ceuA_ 24.6 22 PDB header:viral protein Chain: A: PDB Molecule:protein (hiv-1 regulatory protein n-terminal PDBTitle: nmr structure of the (1-51) n-terminal domain of the hiv-12 regulatory protein 20 d1dl2a_ 23.7 17 Fold:alpha/alpha toroid Superfamily:Seven-hairpin glycosidases Family:Class I alpha-1;2-mannosidase, catalytic domain 21 c3t4aG_ not modelled 23.4 25 PDB header:immune system Chain: G: PDB Molecule:fibrinogen-binding protein; PDBTitle: structure of a truncated form of staphylococcal complement inhibitor b2 bound to human c3c at 3.4 angstrom resolution 22 d1x9da1 not modelled 23.3 20 Fold:alpha/alpha toroid Superfamily:Seven-hairpin glycosidases Family:Class I alpha-1;2-mannosidase, catalytic domain 23 c1x9dA_ not modelled 23.3 20 PDB header:hydrolase Chain: A: PDB Molecule:endoplasmic reticulum mannosyl-oligosaccharide 1, PDBTitle: crystal structure of human class i alpha-1,2-mannosidase in2 complex with thio-disaccharide substrate analogue 24 d2zdra2 not modelled 23.1 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 25 c2kfvA_ not modelled 22.1 13 PDB header:isomerase Chain: A: PDB Molecule:fk506-binding protein 3; PDBTitle: structure of the amino-terminal domain of human fk506-2 binding protein 3 / northeast structural genomics3 consortium target ht99a 26 c2vo9C_ not modelled 21.0 16 PDB header:hydrolase Chain: C: PDB Molecule:l-alanyl-d-glutamate peptidase; PDBTitle: crystal structure of the enzymatically active domain of the2 listeria monocytogenes bacteriophage 500 endolysin ply500 27 c1g6iA_ not modelled 20.6 17 PDB header:hydrolase Chain: A: PDB Molecule:class i alpha-1,2-mannosidase; PDBTitle: crystal structure of the yeast alpha-1,2-mannosidase with bound 1-2 deoxymannojirimycin at 1.59 a resolution 28 c2gtqA_ not modelled 18.4 12 PDB header:hydrolase Chain: A: PDB Molecule:aminopeptidase n; PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis 29 d1lvfa_ not modelled 18.2 22 Fold:STAT-like Superfamily:t-snare proteins Family:t-snare proteins 30 d1x2na1 not modelled 17.7 18 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Homeodomain 31 d1hcua_ not modelled 17.2 11 Fold:alpha/alpha toroid Superfamily:Seven-hairpin glycosidases Family:Class I alpha-1;2-mannosidase, catalytic domain 32 d1qd1a2 not modelled 17.0 20 Fold:Ferredoxin-like Superfamily:Formiminotransferase domain of formiminotransferase-cyclodeaminase. Family:Formiminotransferase domain of formiminotransferase-cyclodeaminase. 33 d1nxca_ not modelled 16.8 16 Fold:alpha/alpha toroid Superfamily:Seven-hairpin glycosidases Family:Class I alpha-1;2-mannosidase, catalytic domain 34 d1m15a1 not modelled 16.7 19 Fold:Guanido kinase N-terminal domain Superfamily:Guanido kinase N-terminal domain Family:Guanido kinase N-terminal domain 35 d2vo9a1 not modelled 16.6 16 Fold:Hedgehog/DD-peptidase Superfamily:Hedgehog/DD-peptidase Family:VanY-like 36 c3bpqC_ not modelled 16.3 26 PDB header:toxin Chain: C: PDB Molecule:antitoxin relb3; PDBTitle: crystal structure of relb-rele antitoxin-toxin complex from2 methanococcus jannaschii 37 d2oc6a1 not modelled 15.8 23 Fold:Secretion chaperone-like Superfamily:YdhG-like Family:YdhG-like 38 c3fpvC_ not modelled 15.7 10 PDB header:heme binding protein Chain: C: PDB Molecule:extracellular haem-binding protein; PDBTitle: crystal structure of hbps 39 c2kvrA_ not modelled 15.6 4 PDB header:protein binding Chain: A: PDB Molecule:ubiquitin carboxyl-terminal hydrolase 7; PDBTitle: solution nmr structure of human ubiquitin specific protease2 usp7 ubl domain (residues 537-664). nesg target hr4395c/3 sgc-toronto 40 d1du6a_ not modelled 15.4 14 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Homeodomain 41 d1ndba1 not modelled 15.3 23 Fold:CoA-dependent acyltransferases Superfamily:CoA-dependent acyltransferases Family:Choline/Carnitine O-acyltransferase 42 c2nrzB_ not modelled 14.9 19 PDB header:hydrolase Chain: B: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the c-terminal half of uvrc bound to2 its catalytic divalent cation 43 c3ayhA_ not modelled 14.7 22 PDB header:transcription Chain: A: PDB Molecule:dna-directed rna polymerase iii subunit rpc9; PDBTitle: crystal structure of the c17/25 subcomplex from s. pombe rna2 polymerase iii 44 d2ri9a1 not modelled 14.3 13 Fold:alpha/alpha toroid Superfamily:Seven-hairpin glycosidases Family:Class I alpha-1;2-mannosidase, catalytic domain 45 d3cx5i1 not modelled 13.9 6 Fold:Single transmembrane helix Superfamily:Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) Family:Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 46 c1krfA_ not modelled 13.8 13 PDB header:hydrolase Chain: A: PDB Molecule:mannosyl-oligosaccharide alpha-1,2-mannosidase; PDBTitle: structure of p. citrinum alpha 1,2-mannosidase reveals the basis for2 differences in specificity of the er and golgi class i enzymes 47 c2xr9A_ not modelled 13.8 26 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) 48 c3izbU_ not modelled 12.9 20 PDB header:ribosome Chain: U: PDB Molecule:40s ribosomal protein s24; PDBTitle: localization of the small subunit ribosomal proteins into a 6.1 a2 cryo-em map of saccharomyces cerevisiae translating 80s ribosome 49 d1mv8a1 not modelled 12.8 28 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:UDP-glucose/GDP-mannose dehydrogenase dimerisation domain 50 d1miua2 not modelled 12.8 8 Fold:BRCA2 tower domain Superfamily:BRCA2 tower domain Family:BRCA2 tower domain 51 d1ftra2 not modelled 12.7 86 Fold:Ferredoxin-like Superfamily:Formylmethanofuran:tetrahydromethanopterin formyltransferase Family:Formylmethanofuran:tetrahydromethanopterin formyltransferase 52 c3mlcC_ not modelled 12.6 20 PDB header:isomerase Chain: C: PDB Molecule:fg41 malonate semialdehyde decarboxylase; PDBTitle: crystal structure of fg41msad inactivated by 3-chloropropiolate 53 d2g1da1 not modelled 12.2 9 Fold:Ribosomal proteins S24e, L23 and L15e Superfamily:Ribosomal proteins S24e, L23 and L15e Family:Ribosomal protein S24e 54 d1m5sa2 not modelled 12.1 86 Fold:Ferredoxin-like Superfamily:Formylmethanofuran:tetrahydromethanopterin formyltransferase Family:Formylmethanofuran:tetrahydromethanopterin formyltransferase 55 d1mylb_ not modelled 12.1 62 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 56 d1m5ha2 not modelled 12.0 86 Fold:Ferredoxin-like Superfamily:Formylmethanofuran:tetrahydromethanopterin formyltransferase Family:Formylmethanofuran:tetrahydromethanopterin formyltransferase 57 c3ezkB_ not modelled 12.0 29 PDB header:hydrolase Chain: B: PDB Molecule:dna packaging protein gp17; PDBTitle: bacteriophage t4 gp17 motor assembly based on crystal2 structures and cryo-em reconstructions 58 d1eg1a_ not modelled 12.0 26 Fold:Concanavalin A-like lectins/glucanases Superfamily:Concanavalin A-like lectins/glucanases Family:Glycosyl hydrolase family 7 catalytic core 59 c2vzaD_ not modelled 11.9 29 PDB header:cell adhesion Chain: D: PDB Molecule:cell filamentation protein; PDBTitle: type iv secretion system effector protein bepa 60 c3pbpL_ not modelled 11.7 80 PDB header:transport protein,structural protein Chain: L: PDB Molecule:nucleoporin nup159; PDBTitle: structure of the yeast heterotrimeric nup82-nup159-nup116 nucleoporin2 complex 61 d1x6ma_ not modelled 11.5 18 Fold:Mss4-like Superfamily:Mss4-like Family:Glutathione-dependent formaldehyde-activating enzyme, Gfa 62 c3pg8B_ not modelled 11.5 13 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 63 d1zxoa1 not modelled 11.2 57 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 64 c2xrgA_ not modelled 11.2 26 PDB header:hydrolase Chain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor 65 c2dmnA_ not modelled 11.1 24 PDB header:transcription Chain: A: PDB Molecule:homeobox protein tgif2lx; PDBTitle: the solution structure of the homeobox domain of human2 homeobox protein tgif2lx 66 d2a2la1 not modelled 11.1 10 Fold:Profilin-like Superfamily:GlcG-like Family:GlcG-like 67 d1crka1 not modelled 10.8 19 Fold:Guanido kinase N-terminal domain Superfamily:Guanido kinase N-terminal domain Family:Guanido kinase N-terminal domain 68 c3bbnR_ not modelled 10.8 38 PDB header:ribosome Chain: R: PDB Molecule:ribosomal protein s18; PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome. 69 c3e38A_ not modelled 10.6 29 PDB header:hydrolase Chain: A: PDB Molecule:two-domain protein containing predicted php-like metal- PDBTitle: crystal structure of a two-domain protein containing predicted php-2 like metal-dependent phosphoesterase (bvu_3505) from bacteroides3 vulgatus atcc 8482 at 2.20 a resolution 70 d1myla_ not modelled 10.6 62 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 71 c3mgwA_ not modelled 10.5 25 PDB header:hydrolase Chain: A: PDB Molecule:lysozyme g; PDBTitle: thermodynamics and structure of a salmon cold-active goose-type2 lysozyme 72 c3cezA_ not modelled 10.4 29 PDB header:oxidoreductase Chain: A: PDB Molecule:methionine-r-sulfoxide reductase; PDBTitle: crystal structure of methionine-r-sulfoxide reductase from2 burkholderia pseudomallei 73 c1w9iA_ not modelled 10.3 13 PDB header:myosin Chain: A: PDB Molecule:myosin ii heavy chain; PDBTitle: myosin ii dictyostelium discoideum motor domain s456y bound2 with mgadp-befx 74 d1t1ua1 not modelled 10.2 23 Fold:CoA-dependent acyltransferases Superfamily:CoA-dependent acyltransferases Family:Choline/Carnitine O-acyltransferase 75 c2y8pA_ not modelled 10.2 8 PDB header:lyase Chain: A: PDB Molecule:endo-type membrane-bound lytic murein transglycosylase a; PDBTitle: crystal structure of an outer membrane-anchored endolytic2 peptidoglycan lytic transglycosylase (mlte) from3 escherichia coli 76 c2ktrA_ not modelled 10.2 7 PDB header:signaling protein, transport protein Chain: A: PDB Molecule:sequestosome-1; PDBTitle: nmr structure of p62 pb1 dimer determined based on pcs 77 d1bazb_ not modelled 10.1 62 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 78 c2nrrA_ not modelled 10.1 25 PDB header:hydrolase Chain: A: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of the c-terminal rnaseh endonuclase2 domain of uvrc 79 c2l1uA_ not modelled 10.0 50 PDB header:oxidoreductase Chain: A: PDB Molecule:methionine-r-sulfoxide reductase b2, mitochondrial; PDBTitle: structure-functional analysis of mammalian msrb2 protein 80 c3c65A_ not modelled 10.0 12 PDB header:hydrolase Chain: A: PDB Molecule:uvrabc system protein c; PDBTitle: crystal structure of bacillus stearothermophilus uvrc 5'2 endonuclease domain 81 c3mnwP_ not modelled 9.9 30 PDB header:immune system Chain: P: PDB Molecule:gp41; PDBTitle: crystal structure of the non-neutralizing hiv antibody 13h11 fab2 fragment with a gp41 mper-derived peptide in a helical conformation 82 d1xrsb2 not modelled 9.9 16 Fold:Dodecin subunit-like Superfamily:D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain Family:D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain 83 d1atia2 not modelled 9.9 10 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 84 d1b28a_ not modelled 9.7 62 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 85 d1qh4a1 not modelled 9.6 13 Fold:Guanido kinase N-terminal domain Superfamily:Guanido kinase N-terminal domain Family:Guanido kinase N-terminal domain 86 c2p58C_ not modelled 9.5 26 PDB header:transport protein/chaperone Chain: C: PDB Molecule:putative type iii secretion protein yscg; PDBTitle: structure of the yersinia pestis type iii secretion system2 needle protein yscf in complex with its chaperones3 ysce/yscg 87 d1jjcb2 not modelled 9.4 22 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Domains B1 and B5 of PheRS-beta, PheT 88 d2ctda1 not modelled 9.4 44 Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2 89 d1xm0a1 not modelled 9.4 50 Fold:Mss4-like Superfamily:Mss4-like Family:SelR domain 90 d2qkwa1 not modelled 9.3 32 Fold:immunoglobulin/albumin-binding domain-like Superfamily:Avirulence protein AvrPto Family:Avirulence protein AvrPto 91 c2qkwA_ not modelled 9.3 32 PDB header:transferase Chain: A: PDB Molecule:avirulence protein; PDBTitle: structural basis for activation of plant immunity by2 bacterial effector protein avrpto 92 c3kztB_ not modelled 9.3 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein of unknown function (np_812423.1) from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution 93 c2k8dA_ not modelled 9.2 43 PDB header:oxidoreductase Chain: A: PDB Molecule:peptide methionine sulfoxide reductase msrb; PDBTitle: solution structure of a zinc-binding methionine sulfoxide reductase 94 c1l6jA_ not modelled 9.2 60 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-9; PDBTitle: crystal structure of human matrix metalloproteinase mmp92 (gelatinase b). 95 d1myka_ not modelled 9.2 62 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 96 c1xuzA_ not modelled 9.2 19 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 97 c3mnzP_ not modelled 9.1 30 PDB header:immune system Chain: P: PDB Molecule:gp41 mper-derived peptide; PDBTitle: crystal structure of the non-neutralizing hiv antibody 13h11 fab2 fragment with a gp41 mper-derived peptide bearing ala substitutions3 in a helical conformation 98 d1bdta_ not modelled 9.0 62 Fold:Ribbon-helix-helix Superfamily:Ribbon-helix-helix Family:Arc/Mnt-like phage repressors 99 c2kl4A_ not modelled 9.0 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bh2032 protein; PDBTitle: nmr structure of the protein nb7804a

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0