Email l.a.kelley@imperial.ac.uk Description P11072 Date Thu Jan 5 11:32:29 GMT 2012 Unique Job ID 707622b2c155c55c

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3c37B_ 97.4 41 PDB header:hydrolase Chain: B: PDB Molecule:peptidase, m48 family; PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a 2 c3dtkA_ 91.3 32 PDB header:gene regulation Chain: A: PDB Molecule:irre protein; PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae 3 c3cqbB_ 69.2 28 PDB header:hydrolase Chain: B: PDB Molecule:probable protease htpx homolog; PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633 4 c3k7lA_ 36.1 29 PDB header:hydrolase Chain: A: PDB Molecule:atragin; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 5 c2e3xA_ 35.0 40 PDB header:hydrolase, blood clotting, toxin Chain: A: PDB Molecule:coagulation factor x-activating enzyme heavy chain; PDBTitle: crystal structure of russell's viper venom metalloproteinase 6 c2erpA_ 34.3 29 PDB header:toxin Chain: A: PDB Molecule:vascular apoptosis-inducing protein 1; PDBTitle: crystal structure of vascular apoptosis-inducing protein-1(inhibitor-2 bound form) 7 c2l0rA_ 32.3 40 PDB header:hydrolase,toxin Chain: A: PDB Molecule:lethal factor; PDBTitle: conformational dynamics of the anthrax lethal factor catalytic center 8 d4aiga_ 31.1 31 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 9 d1atla_ 31.0 23 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 10 c2dw1B_ 31.0 36 PDB header:apoptosis, toxin Chain: B: PDB Molecule:catrocollastatin; PDBTitle: crystal structure of vap2 from crotalus atrox venom (form 2-2 crystal) 11 c2rjpC_ 27.1 33 PDB header:hydrolase Chain: C: PDB Molecule:adamts-4; PDBTitle: crystal structure of adamts4 with inhibitor bound 12 d1r55a_ 27.0 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 13 d1q0qa1 26.7 19 Fold:Left-handed superhelix Superfamily:1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain Family:1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 14 c2v4bB_ 25.3 42 PDB header:hydrolase Chain: B: PDB Molecule:adamts-1; PDBTitle: crystal structure of human adamts-1 catalytic domain and2 cysteine-rich domain (apo-form) 15 c3b8zB_ 25.1 42 PDB header:hydrolase Chain: B: PDB Molecule:protein adamts-5; PDBTitle: high resolution crystal structure of the catalytic domain2 of adamts-5 (aggrecanase-2) 16 d1quaa_ 24.1 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 17 d1vpra1 23.7 25 Fold:Lipocalins Superfamily:Lipocalins Family:Dinoflagellate luciferase repeat 18 d1r0ka1 23.5 22 Fold:Left-handed superhelix Superfamily:1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain Family:1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 19 c2rjqA_ 22.7 42 PDB header:hydrolase Chain: A: PDB Molecule:adamts-5; PDBTitle: crystal structure of adamts5 with inhibitor bound 20 c1yp1A_ 22.5 33 PDB header:hydrolase Chain: A: PDB Molecule:fii; PDBTitle: crystal structure of a non-hemorrhagic fibrin(ogen)olytic2 metalloproteinase from venom of agkistrodon acutus 21 d1hfca_ not modelled 22.5 30 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 22 d1eaka2 not modelled 22.3 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 23 d1j7na2 not modelled 22.2 16 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Anthrax toxin lethal factor, N- and C-terminal domains 24 d1nd1a_ not modelled 22.0 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 25 d1bswa_ not modelled 21.9 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 26 d1wnia_ not modelled 21.7 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 27 d2i47a1 not modelled 21.6 21 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TNF-alpha converting enzyme, TACE, catalytic domain 28 d1qiba_ not modelled 21.3 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 29 d1cxva_ not modelled 21.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 30 d1y93a1 not modelled 21.2 44 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 31 d1cgla_ not modelled 20.7 30 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 32 c2i47A_ not modelled 20.7 25 PDB header:hydrolase Chain: A: PDB Molecule:adam 17; PDBTitle: crystal structure of catalytic domain of tace with inhibitor 33 d1hova_ not modelled 19.9 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 34 c2xs4A_ not modelled 19.9 44 PDB header:hydrolase Chain: A: PDB Molecule:karilysin protease; PDBTitle: structure of karilysin catalytic mmp domain in complex with2 magnesium 35 d1xuca1 not modelled 19.8 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 36 d1g9ka2 not modelled 19.4 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 37 d1hy7a_ not modelled 19.3 44 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 38 d1i76a_ not modelled 19.1 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 39 d1kufa_ not modelled 18.9 27 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Reprolysin-like 40 d1hv5a_ not modelled 18.8 44 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 41 c3k7nA_ not modelled 18.6 27 PDB header:hydrolase Chain: A: PDB Molecule:k-like; PDBTitle: structures of two elapid snake venom metalloproteases with2 distinct activities highlight the disulfide patterns in the3 d domain of adamalysin family proteins 42 d1k7ia2 not modelled 18.3 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 43 d2ovxa1 not modelled 18.1 22 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 44 d1mmqa_ not modelled 17.9 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 45 d1t3ta7 not modelled 17.7 10 Fold:PurM C-terminal domain-like Superfamily:PurM C-terminal domain-like Family:PurM C-terminal domain-like 46 d1sata2 not modelled 17.5 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 47 d1fbla2 not modelled 17.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 48 d1bqqm_ not modelled 17.2 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 49 c3b4rB_ not modelled 17.1 24 PDB header:hydrolase Chain: B: PDB Molecule:putative zinc metalloprotease mj0392; PDBTitle: site-2 protease from methanocaldococcus jannaschii 50 c2jsdA_ not modelled 17.0 33 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-20; PDBTitle: solution structure of mmp20 complexed with nngh 51 d1rm8a_ not modelled 17.0 25 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 52 d1q3aa_ not modelled 15.9 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Matrix metalloproteases, catalytic domain 53 c3sksA_ not modelled 15.7 36 PDB header:hydrolase Chain: A: PDB Molecule:putative oligoendopeptidase f; PDBTitle: crystal structure of a putative oligoendopeptidase f from bacillus2 anthracis str. ames 54 c1slmA_ not modelled 15.3 38 PDB header:hydrolase Chain: A: PDB Molecule:stromelysin-1; PDBTitle: crystal structure of fibroblast stromelysin-1: the c-truncated human2 proenzyme 55 c2h1jA_ not modelled 15.1 36 PDB header:hydrolase Chain: A: PDB Molecule:oligoendopeptidase f; PDBTitle: 3.1 a x-ray structure of putative oligoendopeptidase f: crystals grown2 by microfluidic seeding 56 c3phzA_ not modelled 14.6 29 PDB header:sugar binding protein Chain: A: PDB Molecule:ricin b-related lectin; PDBTitle: crystal structure analysis of polyporus squamosus lectin bound to2 human-type influenza-binding epitope neu5aca2-6galb1-4glcnac 57 c3ce2A_ not modelled 14.6 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative peptidase; PDBTitle: crystal structure of putative peptidase from chlamydophila abortus 58 c3g5cA_ not modelled 14.0 25 PDB header:membrane protein Chain: A: PDB Molecule:adam 22; PDBTitle: structural and biochemical studies on the ectodomain of human adam22 59 d1kapp2 not modelled 13.5 50 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Serralysin-like metalloprotease, catalytic (N-terminal) domain 60 c2vqxA_ not modelled 12.4 21 PDB header:hydrolase Chain: A: PDB Molecule:metalloproteinase; PDBTitle: precursor of protealysin, metalloproteinase from serratia2 proteamaculans. 61 d1npca_ not modelled 12.3 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 62 c1y791_ not modelled 11.7 36 PDB header:hydrolase Chain: 1: PDB Molecule:peptidyl-dipeptidase dcp; PDBTitle: crystal structure of the e.coli dipeptidyl carboxypeptidase2 dcp in complex with a peptidic inhibitor 63 d2ilxa1 not modelled 11.7 24 Fold:LigT-like Superfamily:LigT-like Family:2',3'-cyclic nucleotide 3'-phosphodiesterase, catalytic domain 64 c3nqxA_ not modelled 11.7 29 PDB header:hydrolase Chain: A: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of vibriolysin mcp-02 mature enzyme, a zinc2 metalloprotease from m4 family 65 c3dl1A_ not modelled 11.0 9 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent hydrolase; PDBTitle: crystal structure of a putative metal-dependent hydrolase2 (yp_001336084.1) from klebsiella pneumoniae subsp. pneumoniae mgh3 78578 at 2.20 a resolution 66 d1kjpa_ not modelled 10.4 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 67 c1jiwP_ not modelled 10.4 50 PDB header:hydrolase/hyrolase inhibitor Chain: P: PDB Molecule:alkaline metalloproteinase; PDBTitle: crystal structure of the apr-aprin complex 68 d1bqba_ not modelled 10.3 43 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 69 c3ac6A_ not modelled 9.0 16 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylformylglycinamidine synthase 2; PDBTitle: crystal structure of purl from thermus thermophilus 70 c3nqzB_ not modelled 8.6 29 PDB header:hydrolase Chain: B: PDB Molecule:secreted metalloprotease mcp02; PDBTitle: crystal structure of the autoprocessed vibriolysin mcp-02 with e369a2 mutation 71 c3ba0A_ not modelled 8.6 33 PDB header:hydrolase Chain: A: PDB Molecule:macrophage metalloelastase; PDBTitle: crystal structure of full-length human mmp-12 72 c2cltB_ not modelled 8.5 22 PDB header:hydrolase Chain: B: PDB Molecule:interstitial collagenase; PDBTitle: crystal structure of the active form (full-length) of human2 fibroblast collagenase. 73 d1pyta_ not modelled 8.2 14 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 74 d1t1ra3 not modelled 8.0 33 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 75 d1i1ip_ not modelled 8.0 40 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Neurolysin-like 76 d2ejqa1 not modelled 7.9 38 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:TTHA0227-like 77 d1tx3a1 not modelled 7.8 21 Fold:Restriction endonuclease-like Superfamily:Restriction endonuclease-like Family:Restriction endonuclease HincII 78 d1c7ka_ not modelled 7.6 44 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Zinc protease 79 d1x7va_ not modelled 7.3 15 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 80 c2fb0A_ not modelled 7.2 0 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of conserved protein of unknown function from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution, possible3 oxidoreductase 81 d1jqga2 not modelled 7.1 7 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 82 d1t06a_ not modelled 6.7 28 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:BC3264-like 83 d1ayea2 not modelled 6.6 18 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 84 d2boaa2 not modelled 6.6 14 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 85 d1u4ga_ not modelled 6.5 29 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Thermolysin-like 86 d1o6xa_ not modelled 6.4 18 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 87 d1nsaa2 not modelled 6.3 11 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 88 c1l6jA_ not modelled 6.1 54 PDB header:hydrolase Chain: A: PDB Molecule:matrix metalloproteinase-9; PDBTitle: crystal structure of human matrix metalloproteinase mmp92 (gelatinase b). 89 d1s4bp_ not modelled 6.0 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Neurolysin-like 90 d1v54m_ not modelled 6.0 28 Fold:Single transmembrane helix Superfamily:Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) Family:Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) 91 c2omoC_ not modelled 5.9 15 PDB header:oxidoreductase Chain: C: PDB Molecule:duf176; PDBTitle: putative antibiotic biosynthesis monooxygenase from nitrosomonas2 europaea 92 d1pbaa_ not modelled 5.9 11 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 93 d2ajfa1 not modelled 5.8 33 Fold:Zincin-like Superfamily:Metalloproteases ("zincins"), catalytic domain Family:Neurolysin-like 94 c3p1vB_ not modelled 5.7 27 PDB header:hydrolase Chain: B: PDB Molecule:metallo-endopeptidase; PDBTitle: crystal structure of a metallo-endopeptidases (bacova_00663) from2 bacteroides ovatus at 1.93 a resolution 95 c1su3A_ not modelled 5.6 26 PDB header:hydrolase Chain: A: PDB Molecule:interstitial collagenase; PDBTitle: x-ray structure of human prommp-1: new insights into2 collagenase action 96 d2ihoa2 not modelled 5.6 9 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:MOA C-terminal domain-like 97 c1om8A_ not modelled 5.5 50 PDB header:hydrolase Chain: A: PDB Molecule:serralysin; PDBTitle: crystal structure of a cold adapted alkaline protease from pseudomonas2 tac ii 18, co-crystallyzed with 10 mm edta 98 d1kwma2 not modelled 5.5 11 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 99 d2cpwa1 not modelled 5.1 33 Fold:RuvA C-terminal domain-like Superfamily:UBA-like Family:UBA domain