Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	A	L	Q	L	L	T	W	S	L	I	L	Y	L	F	A	S	L	A	S	L	F	L	L	G	L	D	R	L	A	I	K	L	S	G	I	T	S	L	V	G	G	V	I	G	I	I	S	G	I	T	Q	L	H	A	G	V	T	L
Secondary structure
SS confidence
Disorder		?	?																							?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	A	R	F	A	P	P	F	E	F	A	D	L	T	L	R	M	D	S	L	S	A	F	M	V	L	V	I	S	L	L	V	V	V	C	S	L	Y	S	L	T	Y	M	R	E	Y	E	G	K	G	A	A	A	M	G	F	F	M	N	I
Secondary structure
SS confidence
Disorder																																																?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		F	I	A	S	M	V	A	L	L	V	M	D	N	A	F	W	F	I	V	L	F	E	M	M	S	L	S	S	W	F	L	V	I	A	R	Q	D	K	T	S	I	N	A	G	M	L	Y	F	F	I	A	H	A	G	S	V	L	I	M	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	F	L	L	M	G	R	E	S	G	S	L	D	F	A	S	F	R	T	L	S	L	S	P	G	L	A	S	A	V	F	L	L	A	F	F	G	F	G	A	K	A	G	M	M	P	L	H	S	W	L	P	R	A	H	P	A	A	P	S
Secondary structure
SS confidence
Disorder																				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	A	S	A	L	M	S	G	V	M	V	K	I	G	I	F	G	I	L	K	V	A	M	D	L	L	A	Q	T	G	L	P	L	W	W	G	I	L	V	M	A	I	G	A	I	S	A	L	L	G	V	L	Y	A	L	A	E	Q	D	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		K	R	L	L	A	W	S	T	V	E	N	V	G	I	I	L	L	A	V	G	V	A	M	V	G	L	S	L	H	D	P	L	L	T	V	V	G	L	L	G	A	L	F	H	L	L	N	H	A	L	F	K	G	L	L	F	L	G	A	G
Secondary structure
SS confidence
Disorder																											?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	I	I	S	R	L	H	T	H	D	M	E	K	M	G	A	L	A	K	R	M	P	W	T	A	A	A	C	L	I	G	C	L	A	I	S	A	I	P	P	L	N	G	F	I	S	E	W	Y	T	W	Q	S	L	F	S	L	S	R	V
Secondary structure
SS confidence
Disorder															?	?																																									?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		E	A	V	A	L	Q	L	A	G	P	I	A	M	V	M	L	A	V	T	G	G	L	A	V	M	C	F	V	K	M	Y	G	I	T	F	C	G	A	P	R	S	T	H	A	E	E	A	Q	E	V	P	N	T	M	I	V	A	M	L	L
Secondary structure
SS confidence
Disorder		?	?	?	?																																					?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		L	A	A	L	C	V	L	I	A	L	S	A	S	W	L	A	P	K	I	M	H	I	A	H	A	F	T	N	T	P	P	A	T	V	A	S	G	I	A	L	V	P	G	T	F	H	T	Q	V	T	P	S	L	L	L	L	L	L	L	A
Secondary structure
SS confidence
Disorder																																	?	?					?	?	?				?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		M	P	L	L	P	G	L	Y	W	L	W	C	R	S	R	R	A	A	F	R	R	T	G	D	A	W	A	C	G	Y	G	W	E	N	A	M	A	P	S	G	N	G	V	M	Q	P	L	R	V	V	F	S	A	L	F	R	L	R	Q	Q
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?	?																?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		L	D	P	T	L	R	L	N	K	G	L	A	H	V	T	A	R	A	Q	S	T	E	P	F	W	D	E	R	V	I	R	P	I	V	S	A	T	Q	R	L	A	K	E	I	Q	H	L	Q	S	G	D	F	R	L	Y	C	L	Y	V	V
Secondary structure
SS confidence
Disorder									?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.
Sequence		A	A	L	V	V	L	L	I	A	I	A	V
Secondary structure
SS confidence
Disorder											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3rko chain L Region: 4 - 672 Aligned: 596 Modelled: 620 Confidence: 100.0% Identity: 23% PDB header:oxidoreductase Chain: L: PDB Molecule:nadh-quinone oxidoreductase subunit l; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 3rko chain M Region: 6 - 508 Aligned: 475 Modelled: 503 Confidence: 100.0% Identity: 24% PDB header:oxidoreductase Chain: M: PDB Molecule:nadh-quinone oxidoreductase subunit m; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 3rko chain N Region: 1 - 506 Aligned: 467 Modelled: 506 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: N: PDB Molecule:nadh-quinone oxidoreductase subunit n; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 3rko chain K Region: 114 - 200 Aligned: 87 Modelled: 87 Confidence: 80.5% Identity: 17% PDB header:oxidoreductase Chain: K: PDB Molecule:nadh-quinone oxidoreductase subunit k; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 1a6q chain A domain 1 Region: 383 - 417 Aligned: 35 Modelled: 35 Confidence: 31.6% Identity: 11% Fold: Another 3-helical bundle Superfamily: Protein serine/threonine phosphatase 2C, C-terminal domain Family: Protein serine/threonine phosphatase 2C, C-terminal domain Phyre2 PDB 2l3i chain A Region: 294 - 305 Aligned: 12 Modelled: 12 Confidence: 28.2% Identity: 50% PDB header:antimicrobial protein Chain: A: PDB Molecule:aoxki4a, antimicrobial peptide in spider venom; PDBTitle: oxki4a, spider derived antimicrobial peptide Phyre2 PDB 2gf4 chain A domain 1 Region: 352 - 381 Aligned: 30 Modelled: 29 Confidence: 18.7% Identity: 23% Fold: immunoglobulin/albumin-binding domain-like Superfamily: Vng1086c-like Family: Vng1086c-like Phyre2 PDB 1o8b chain B domain 1 Region: 297 - 322 Aligned: 23 Modelled: 26 Confidence: 17.2% Identity: 17% Fold: NagB/RpiA/CoA transferase-like Superfamily: NagB/RpiA/CoA transferase-like Family: D-ribose-5-phosphate isomerase (RpiA), catalytic domain Phyre2 PDB 1s1q chain A Region: 225 - 240 Aligned: 16 Modelled: 16 Confidence: 15.3% Identity: 31% Fold: UBC-like Superfamily: UBC-like Family: UEV domain Phyre2 PDB 1j4n chain A Region: 345 - 469 Aligned: 106 Modelled: 125 Confidence: 15.1% Identity: 17% Fold: Aquaporin-like Superfamily: Aquaporin-like Family: Aquaporin-like Phyre2 PDB 1iij chain A Region: 648 - 672 Aligned: 25 Modelled: 25 Confidence: 13.5% Identity: 20% PDB header:signaling protein Chain: A: PDB Molecule:erbb-2 receptor protein-tyrosine kinase; PDBTitle: solution structure of the neu/erbb-2 membrane spanning2 segment Phyre2 PDB 3rko chain F Region: 443 - 562 Aligned: 107 Modelled: 120 Confidence: 13.2% Identity: 16% PDB header:oxidoreductase Chain: F: PDB Molecule:nadh-quinone oxidoreductase subunit j; PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution Phyre2 PDB 2q7r chain A domain 1 Region: 96 - 140 Aligned: 45 Modelled: 45 Confidence: 12.8% Identity: 11% Fold: MAPEG domain-like Superfamily: MAPEG domain-like Family: MAPEG domain Phyre2 PDB 1nek chain D Region: 162 - 231 Aligned: 62 Modelled: 70 Confidence: 12.8% Identity: 16% Fold: Heme-binding four-helical bundle Superfamily: Fumarate reductase respiratory complex transmembrane subunits Family: Succinate dehydrogenase/Fumarate reductase transmembrane subunits (SdhC/FrdC and SdhD/FrdD) Phyre2 PDB 3na2 chain C Region: 230 - 241 Aligned: 12 Modelled: 12 Confidence: 12.7% Identity: 58% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of protein of unknown function from mine drainage2 metagenome leptospirillum rubarum Phyre2 PDB 2axt chain I domain 1 Region: 85 - 113 Aligned: 29 Modelled: 29 Confidence: 12.6% Identity: 7% Fold: Single transmembrane helix Superfamily: Photosystem II reaction center protein I, PsbI Family: PsbI-like Phyre2 PDB 3d37 chain A domain 2 Region: 230 - 236 Aligned: 7 Modelled: 7 Confidence: 12.4% Identity: 57% Fold: Phage tail proteins Superfamily: Phage tail proteins Family: Baseplate protein-like Phyre2 PDB 1lgh chain A Region: 228 - 255 Aligned: 28 Modelled: 28 Confidence: 12.2% Identity: 29% Fold: Light-harvesting complex subunits Superfamily: Light-harvesting complex subunits Family: Light-harvesting complex subunits Phyre2 PDB 1n9w chain A domain 2 Region: 397 - 404 Aligned: 8 Modelled: 8 Confidence: 10.5% Identity: 50% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1n9w chain A Region: 397 - 404 Aligned: 8 Modelled: 8 Confidence: 10.4% Identity: 50% PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus Phyre2 1 c3rkoL_ 2 c3rkoM_ 3 c3rkoN_ 4 c3rkoK_ 5 d1a6qa1 6 c2l3iA_ 7 d2gf4a1 8 d1o8bb1 9 d1s1qa_ 10 d1j4na_ 11 c1iijA_ 12 c3rkoF_ 13 d2q7ra1 14 d1nekd_ 15 c3na2C_ 16 d2axti1 17 d3d37a2 18 d1lgha_ 19 d1n9wa2 20 c1n9wA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99