Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP45524
DateThu Jan 5 12:02:54 GMT 2012
Unique Job ID5cf242c9f95fa19c

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1k8qa_
Top template information
Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
Confidence and coverage
Confidence:100.0% Coverage: 85%
289 residues ( 85% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAQITTTDANEFSSSAEFIPMRGFSNCHLQTMLPRLFRRQVKFTPYWQRLELPDGDFVDL
Secondary structure 
SS confidence 
Disorder  ????????????????
?
???
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  AWSENPAQAQHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGWLGVVMHFRGCSGEPNRMH
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  RIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLACLLAKEGNDLPVDAAVIVSA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  PFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDD
Secondary structure 
SS confidence 
Disorder 
??
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  LITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIHAKDDPFMDHQVIPKPESLPPQVEY
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340
Sequence  QLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTYLEAKSC
Secondary structure 
SS confidence 
Disorder 
?????
?????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1k8q chain A

3D model

Region: 43 - 333
Aligned: 289
Modelled: 291
Confidence: 100.0%
Identity: 14%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Gastric lipase

Phyre2

PDB 1hlg chain A

3D model

Region: 42 - 336
Aligned: 293
Modelled: 293
Confidence: 100.0%
Identity: 12%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Gastric lipase

Phyre2

PDB 1cr6 chain A

3D model

Region: 38 - 333
Aligned: 281
Modelled: 294
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor

Phyre2

PDB 2vav chain L

3D model

Region: 45 - 333
Aligned: 284
Modelled: 289
Confidence: 100.0%
Identity: 13%
PDB header:transferase
Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c
PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak)

Phyre2

PDB 3i1i chain A

3D model

Region: 45 - 335
Aligned: 284
Modelled: 286
Confidence: 100.0%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:homoserine o-acetyltransferase;
PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis

Phyre2

PDB 2b61 chain A domain 1

3D model

Region: 45 - 334
Aligned: 283
Modelled: 290
Confidence: 100.0%
Identity: 17%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: O-acetyltransferase

Phyre2

PDB 2vat chain A domain 1

3D model

Region: 48 - 333
Aligned: 281
Modelled: 286
Confidence: 100.0%
Identity: 15%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: O-acetyltransferase

Phyre2

PDB 3v48 chain B

3D model

Region: 66 - 338
Aligned: 256
Modelled: 273
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd;
PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli

Phyre2

PDB 2qmq chain A

3D model

Region: 45 - 332
Aligned: 271
Modelled: 288
Confidence: 100.0%
Identity: 11%
PDB header:signaling protein
Chain: A: PDB Molecule:protein ndrg2;
PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution

Phyre2

PDB 3jw8 chain A

3D model

Region: 38 - 335
Aligned: 282
Modelled: 298
Confidence: 100.0%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:mgll protein;
PDBTitle: crystal structure of human mono-glyceride lipase

Phyre2

PDB 2hdw chain B

3D model

Region: 37 - 335
Aligned: 290
Modelled: 299
Confidence: 100.0%
Identity: 11%
PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa

Phyre2

PDB 1zd3 chain A domain 2

3D model

Region: 38 - 337
Aligned: 285
Modelled: 296
Confidence: 100.0%
Identity: 14%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Epoxide hydrolase

Phyre2

PDB 1cr6 chain A domain 2

3D model

Region: 39 - 333
Aligned: 280
Modelled: 295
Confidence: 100.0%
Identity: 16%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Epoxide hydrolase

Phyre2

PDB 1mtz chain A

3D model

Region: 48 - 335
Aligned: 275
Modelled: 275
Confidence: 100.0%
Identity: 13%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Proline iminopeptidase-like

Phyre2

PDB 1b6g chain A

3D model

Region: 37 - 333
Aligned: 287
Modelled: 297
Confidence: 100.0%
Identity: 11%
Fold: alpha/beta-Hydrolases
Superfamily: alpha/beta-Hydrolases
Family: Haloalkane dehalogenase

Phyre2

PDB 3om8 chain A

3D model

Region: 48 - 333
Aligned: 260
Modelled: 279
Confidence: 100.0%
Identity: 15%
PDB header:hydrolase
Chain: A: PDB Molecule:probable hydrolase;
PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01

Phyre2

PDB 2y6v chain B

3D model

Region: 52 - 340
Aligned: 281
Modelled: 288
Confidence: 100.0%
Identity: 10%
PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal membrane protein lpx1;
PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i)

Phyre2

PDB 3h04 chain A

3D model

Region: 47 - 334
Aligned: 265
Modelled: 277
Confidence: 100.0%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50

Phyre2

PDB 2wtm chain C

3D model

Region: 46 - 335
Aligned: 249
Modelled: 257
Confidence: 100.0%
Identity: 12%
PDB header:hydrolase
Chain: C: PDB Molecule:est1e;
PDBTitle: est1e from butyrivibrio proteoclasticus

Phyre2

PDB 2hu7 chain A

3D model

Region: 45 - 336
Aligned: 240
Modelled: 246
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase

Phyre2
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d1k8qa_
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d1hlga_
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c1cr6A_
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c2vavL_
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c3i1iA_
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d2b61a1
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d2vata1
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c3v48B_
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c2qmqA_
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c3jw8A_
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c2hdwB_
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d1zd3a2
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d1cr6a2
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d1mtza_
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d1b6ga_
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c3om8A_
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c2y6vB_
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c3h04A_
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c2wtmC_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1k8qa_
100.0 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
2d1hlga_
100.0 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Gastric lipase
3c1cr6A_
100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: crystal structure of murine soluble epoxide hydrolase2 complexed with cpu inhibitor
4c2vavL_
100.0 13 PDB header:transferase
Chain: L: PDB Molecule:acetyl-coa--deacetylcephalosporin c
PDBTitle: crystal structure of deacetylcephalosporin c2 acetyltransferase (dac-soak)
5c3i1iA_
100.0 13 PDB header:transferase
Chain: A: PDB Molecule:homoserine o-acetyltransferase;
PDBTitle: x-ray crystal structure of homoserine o-acetyltransferase from2 bacillus anthracis
6d2b61a1
100.0 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
7d2vata1
100.0 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
8c3v48B_
100.0 16 PDB header:hydrolase
Chain: B: PDB Molecule:putative aminoacrylate hydrolase rutd;
PDBTitle: crystal structure of the putative alpha/beta hydrolase rutd from2 e.coli
9c2qmqA_
100.0 11 PDB header:signaling protein
Chain: A: PDB Molecule:protein ndrg2;
PDBTitle: crystal structure of a n-myc downstream regulated 2 protein (ndrg2,2 syld, ndr2, ai182517, au040374) from mus musculus at 1.70 a3 resolution
10c3jw8A_
100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:mgll protein;
PDBTitle: crystal structure of human mono-glyceride lipase
11c2hdwB_
100.0 11 PDB header:hydrolase
Chain: B: PDB Molecule:hypothetical protein pa2218;
PDBTitle: crystal structure of hypothetical protein pa2218 from pseudomonas2 aeruginosa
12d1zd3a2
100.0 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
13d1cr6a2
100.0 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
14d1mtza_
100.0 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
15d1b6ga_
100.0 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
16c3om8A_
100.0 15 PDB header:hydrolase
Chain: A: PDB Molecule:probable hydrolase;
PDBTitle: the crystal structure of a hydrolase from pseudomonas aeruginosa pa01
17c2y6vB_
100.0 10 PDB header:hydrolase
Chain: B: PDB Molecule:peroxisomal membrane protein lpx1;
PDBTitle: peroxisomal alpha-beta-hydrolase lpx1 (yor084w) from2 saccharomyces cerevisiae (crystal form i)
18c3h04A_
100.0 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein with unknown function from2 staphylococcus aureus subsp. aureus mu50
19c2wtmC_
100.0 12 PDB header:hydrolase
Chain: C: PDB Molecule:est1e;
PDBTitle: est1e from butyrivibrio proteoclasticus
20c2hu7A_
100.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:acylamino-acid-releasing enzyme;
PDBTitle: binding of inhibitors by acylaminoacyl peptidase
21d1c4xa_
not modelled 100.0 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
22c3u1tA_
not modelled 100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:dmma haloalkane dehalogenase;
PDBTitle: haloalkane dehalogenase, dmma, of marine microbial origin
23c3hjuB_
not modelled 100.0 14 PDB header:hydrolase
Chain: B: PDB Molecule:monoglyceride lipase;
PDBTitle: crystal structure of human monoglyceride lipase
24c3qvmA_
not modelled 100.0 11 PDB header:hydrolase
Chain: A: PDB Molecule:olei00960;
PDBTitle: the structure of olei00960, a hydrolase from oleispira antarctica
25c2cjpA_
not modelled 100.0 13 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase;
PDBTitle: structure of potato (solanum tuberosum) epoxide hydrolase i2 (steh1)
26c3oosA_
not modelled 100.0 12 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase family protein;
PDBTitle: the structure of an alpha/beta fold family hydrolase from bacillus2 anthracis str. sterne
27d1azwa_
not modelled 100.0 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
28c2e3jA_
not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:epoxide hydrolase ephb;
PDBTitle: the crystal structure of epoxide hydrolase b (rv1938) from2 mycobacterium tuberculosis at 2.1 angstrom
29c2xuaH_
not modelled 100.0 16 PDB header:hydrolase
Chain: H: PDB Molecule:3-oxoadipate enol-lactonase;
PDBTitle: crystal structure of the enol-lactonase from burkholderia2 xenovorans lb400
30d2pl5a1
not modelled 100.0 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:O-acetyltransferase
31c2r11D_
not modelled 100.0 14 PDB header:hydrolase
Chain: D: PDB Molecule:carboxylesterase np;
PDBTitle: crystal structure of putative hydrolase (2632844) from2 bacillus subtilis at 1.96 a resolution
32c3bwxA_
not modelled 100.0 14 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase;
PDBTitle: crystal structure of an alpha/beta hydrolase (yp_496220.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.50 a resolution
33d1ehya_
not modelled 100.0 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
34c1u2eA_
not modelled 100.0 12 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-ketonona-2,4-dienedioic acid
PDBTitle: crystal structure of the c-c bond hydrolase mhpc
35c2xt0A_
not modelled 100.0 12 PDB header:hydrolase
Chain: A: PDB Molecule:haloalkane dehalogenase;
PDBTitle: dehalogenase dppa from plesiocystis pacifica sir-i
36d1q0ra_
not modelled 100.0 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Aclacinomycin methylesterase RdmC
37c3nwoA_
not modelled 100.0 12 PDB header:hydrolase
Chain: A: PDB Molecule:proline iminopeptidase;
PDBTitle: crystal structure of proline iminopeptidase mycobacterium smegmatis
38d1wm1a_
not modelled 100.0 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Proline iminopeptidase-like
39c1zoiC_
not modelled 100.0 14 PDB header:hydrolase
Chain: C: PDB Molecule:esterase;
PDBTitle: crystal structure of a stereoselective esterase from2 pseudomonas putida ifo12996
40c2jbwB_
not modelled 100.0 20 PDB header:hydrolase
Chain: B: PDB Molecule:2,6-dihydroxy-pseudo-oxynicotine hydrolase;
PDBTitle: crystal structure of the 2,6-dihydroxy-pseudo-oxynicotine2 hydrolase.
41c3fnbB_
not modelled 100.0 13 PDB header:hydrolase
Chain: B: PDB Molecule:acylaminoacyl peptidase smu_737;
PDBTitle: crystal structure of acylaminoacyl peptidase smu_737 from2 streptococcus mutans ua159
42c3llcA_
not modelled 100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:putative hydrolase;
PDBTitle: crystal structure of putative hydrolase (yp_002548124.1) from2 agrobacterium vitis s4 at 1.80 a resolution
43c3kdaB_
not modelled 100.0 13 PDB header:hydrolase
Chain: B: PDB Molecule:cftr inhibitory factor (cif);
PDBTitle: crystal structure of the cftr inhibitory factor cif with the h269a2 mutation
44c2xmzA_
not modelled 100.0 14 PDB header:lyase
Chain: A: PDB Molecule:hydrolase, alpha/beta hydrolase fold family;
PDBTitle: structure of menh from s. aureus
45d2jbwa1
not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:2,6-dihydropseudooxynicotine hydrolase-like
46d1e89a_
not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
47c2q0xA_
not modelled 99.9 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: alpha/beta hydrolase fold protein of unknown function
48c3kxpD_
not modelled 99.9 15 PDB header:hydrolase
Chain: D: PDB Molecule:alpha-(n-acetylaminomethylene)succinic acid
PDBTitle: crystal structure of e-2-(acetamidomethylene)succinate2 hydrolase
49d1a8qa_
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
50c2vf2A_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
PDBTitle: x-ray crystal structure of hsad from mycobacterium2 tuberculosis
51c1y37A_
not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:fluoroacetate dehalogenase;
PDBTitle: structure of fluoroacetate dehalogenase from burkholderia sp. fa1
52d3c70a1
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
53d1hkha_
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
54c2rauA_
not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:putative esterase;
PDBTitle: crystal structure of a putative lipase (np_343859.1) from sulfolobus2 solfataricus at 1.85 a resolution
55c3dqzB_
not modelled 99.9 11 PDB header:lyase
Chain: B: PDB Molecule:alpha-hydroxynitrile lyase-like protein;
PDBTitle: structure of the hydroxynitrile lyase from arabidopsis2 thaliana
56d1l7aa_
not modelled 99.9 15 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
57d2rhwa1
not modelled 99.9 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
58d1a88a_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
59c3qm1A_
not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:cinnamoyl esterase;
PDBTitle: crystal structure of the lactobacillus johnsonii cinnamoyl esterase2 lj0536 s106a mutant in complex with ethylferulate, form ii
60c3c5wP_
not modelled 99.9 11 PDB header:hydrolase
Chain: P: PDB Molecule:pp2a-specific methylesterase pme-1;
PDBTitle: complex between pp2a-specific methylesterase pme-1 and pp2a core2 enzyme
61c2ecfA_
not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase iv;
PDBTitle: crystal structure of dipeptidyl aminopeptidase iv from2 stenotrophomonas maltophilia
62d1uk8a_
not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
63c2yysA_
not modelled 99.9 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:proline iminopeptidase-related protein;
PDBTitle: crystal structure of the proline iminopeptidase-related protein2 ttha1809 from thermus thermophilus hb8
64c3e3aA_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:possible peroxidase bpoc;
PDBTitle: the structure of rv0554 from mycobacterium tuberculosis
65c3l80A_
not modelled 99.9 8 PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein smu.1393c;
PDBTitle: crystal structure of smu.1393c from streptococcus mutans ua159
66d1brta_
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
67c3fsgC_
not modelled 99.9 11 PDB header:hydrolase
Chain: C: PDB Molecule:alpha/beta superfamily hydrolase;
PDBTitle: crystal structure of alpha/beta superfamily hydrolase from oenococcus2 oeni psu-1
68d1m33a_
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Biotin biosynthesis protein BioH
69d1bn7a_
not modelled 99.9 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
70d1xkla_
not modelled 99.9 11 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hydroxynitrile lyase-like
71c2wj4B_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:1h-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase;
PDBTitle: crystal structure of the cofactor-devoid 1-h-3-hydroxy-4-2 oxoquinaldine 2,4-dioxygenase (hod) from arthrobacter3 nitroguajacolicus ru61a anaerobically complexed with its4 natural substrate 1-h-3-hydroxy-4-oxoquinaldine
72d1a8sa_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
73c3fobA_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:bromoperoxidase;
PDBTitle: crystal structure of bromoperoxidase from bacillus anthracis
74c3mveB_
not modelled 99.9 16 PDB header:lyase
Chain: B: PDB Molecule:upf0255 protein vv1_0328;
PDBTitle: crystal structure of a novel pyruvate decarboxylase
75c3azqA_
not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase;
PDBTitle: crystal structure of puromycin hydrolase s511a mutant complexed with2 pgg
76c3r0vA_
not modelled 99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:alpha/beta hydrolase fold protein;
PDBTitle: the crystal structure of an alpha/beta hydrolase from sphaerobacter2 thermophilus dsm 20745.
77d1va4a_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloperoxidase
78c3a2nF_
not modelled 99.9 12 PDB header:hydrolase
Chain: F: PDB Molecule:haloalkane dehalogenase;
PDBTitle: crystal structure of dbja (wild type type ii p21)
79c3e0xB_
not modelled 99.9 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:lipase-esterase related protein;
PDBTitle: the crystal structure of a lipase-esterase related protein2 from clostridium acetobutylicum atcc 824
80d1qo7a_
not modelled 99.9 12 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Epoxide hydrolase
81c3qyjB_
not modelled 99.9 12 PDB header:hydrolase
Chain: B: PDB Molecule:alr0039 protein;
PDBTitle: crystal structure of alr0039, a putative alpha/beta hydrolase from2 nostoc sp pcc 7120.
82c3dyvA_
not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:esterase d;
PDBTitle: snapshots of esterase d from lactobacillus rhamnosus:2 insights into a rotation driven catalytic mechanism
83c3gzjB_
not modelled 99.9 10 PDB header:hydrolase
Chain: B: PDB Molecule:polyneuridine-aldehyde esterase;
PDBTitle: crystal structure of polyneuridine aldehyde esterase2 complexed with 16-epi-vellosimine
84d1mj5a_
not modelled 99.9 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Haloalkane dehalogenase
85c1wprA_
not modelled 99.9 11 PDB header:signaling protein
Chain: A: PDB Molecule:sigma factor sigb regulation protein rsbq;
PDBTitle: crystal structure of rsbq inhibited by pmsf
86c3ibtA_
not modelled 99.9 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase;
PDBTitle: structure of 1h-3-hydroxy-4-oxoquinoline 2,4-dioxygenase (qdo)
87d1ju3a2
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:PepX catalytic domain-like
88c2qruA_
not modelled 99.9 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of an alpha/beta hydrolase superfamily protein from2 enterococcus faecalis
89c3qitB_
not modelled 99.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:polyketide synthase;
PDBTitle: thioesterase domain from curacin biosynthetic pathway
90d1vlqa_
not modelled 99.9 10 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Acetyl xylan esterase-like
91d2fuka1
not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
92c2eepA_
not modelled 99.9 16 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl aminopeptidase iv, putative;
PDBTitle: prolyl tripeptidyl aminopeptidase complexed with an inhibitor
93c3r3xA_
not modelled 99.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:fluoroacetate dehalogenase;
PDBTitle: crystal structure of the fluoroacetate dehalogenase rpa1163 -2 asp110asn/bromoacetate
94c1l7qA_
not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:cocaine esterase;
PDBTitle: ser117ala mutant of bacterial cocaine esterase coce
95c3fcyB_
not modelled 99.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:xylan esterase 1;
PDBTitle: crystal structure of acetyl xylan esterase 1 from2 thermoanaerobacterium sp. jw/sl ys485
96d1tqha_
not modelled 99.9 17 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carboxylesterase/lipase
97d1j1ia_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Carbon-carbon bond hydrolase
98c1j1iA_
not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:meta cleavage compound hydrolase;
PDBTitle: crystal structure of a his-tagged serine hydrolase involved2 in the carbazole degradation (carc enzyme)
99c3bdiA_
not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein ta0194;
PDBTitle: crystal structure of predicted cib-like hydrolase (np_393672.1) from2 thermoplasma acidophilum at 1.45 a resolution
100d1r3da_
not modelled 99.9 14 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Hypothetical protein VC1974
101c2ockA_
not modelled 99.9 13 PDB header:hydrolase
Chain: A: PDB Molecule:valacyclovir hydrolase;
PDBTitle: crystal structure of valacyclovir hydrolase d123n mutant
102c3p2mA_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:possible hydrolase;
PDBTitle: crystal structure of a novel esterase rv0045c from mycobacterium2 tuberculosis
103c2o2gA_
not modelled 99.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:dienelactone hydrolase;
PDBTitle: crystal structure of dienelactone hydrolase (yp_324580.1) from2 anabaena variabilis atcc 29413 at 1.92 a resolution
104c2qvbA_
not modelled 99.9 12 PDB header:hydrolase
Chain: A: PDB Molecule:haloalkane dehalogenase 3;
PDBTitle: crystal structure of haloalkane dehalogenase rv2579 from mycobacterium2 tuberculosis
105c1z68A_
not modelled 99.9 17 PDB header:lyase
Chain: A: PDB Molecule:fibroblast activation protein, alpha subunit;
PDBTitle: crystal structure of human fibroblast activation protein alpha
106c3ksrA_
not modelled 99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative serine hydrolase;
PDBTitle: crystal structure of a putative serine hydrolase (xcc3885) from2 xanthomonas campestris pv. campestris at 2.69 a resolution
107c3hlkB_
not modelled 99.9 14 PDB header:hydrolase
Chain: B: PDB Molecule:acyl-coenzyme a thioesterase 2, mitochondrial;
PDBTitle: crystal structure of human mitochondrial acyl-coa2 thioesterase (acot2)
108c3bf7B_
not modelled 99.9 14 PDB header:hydrolase
Chain: B: PDB Molecule:esterase ybff;
PDBTitle: 1.1 resolution structure of ybff, a new esterase from2 escherichia coli: a unique substrate-binding crevice3 generated by domain arrangement
109c3k2iA_
not modelled 99.9 20 PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 4;
PDBTitle: human acyl-coenzyme a thioesterase 4
110c3flaB_
not modelled 99.9 17 PDB header:hydrolase
Chain: B: PDB Molecule:rifr;
PDBTitle: rifr - type ii thioesterase from rifamycin nrps/pks biosynthetic2 pathway - form 1
111c2g5tA_
not modelled 99.9 14 PDB header:hydrolase
Chain: A: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
112d1uxoa_
not modelled 99.9 18 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:YdeN-like
113c2pseA_
not modelled 99.9 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:renilla-luciferin 2-monooxygenase;
PDBTitle: crystal structures of the luciferase and green fluorescent2 protein from renilla reniformis
114d1ex9a_
not modelled 99.9 13 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Bacterial lipase
115c2qtbB_
not modelled 99.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:dipeptidyl peptidase 4;
PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
116c3qmwD_
not modelled 99.9 17 PDB header:hydrolase
Chain: D: PDB Molecule:thioesterase;
PDBTitle: redj with peg molecule bound in the active site
117c2qjwA_
not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:uncharacterized protein xcc1541;
PDBTitle: crystal structure of a putative hydrolase of the alpha/beta2 superfamily (xcc1541) from xanthomonas campestris pv. campestris at3 1.35 a resolution
118d1imja_
not modelled 99.9 16 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Ccg1/TafII250-interacting factor B (Cib)
119d2i3da1
not modelled 99.9 21 Fold:alpha/beta-Hydrolases
Superfamily:alpha/beta-Hydrolases
Family:Atu1826-like
120c2i3dA_
not modelled 99.9 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein atu1826;
PDBTitle: crystal structure of protein of unknown function atu1826, a putative2 alpha/beta hydrolase from agrobacterium tumefaciens

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0