Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	A	F	T	Y	E	R	V	N	T	P	A	E	A	A	L	S	A	Q	R	V	P	G	A	K	F	I	A	G	G	T	N	L	L	D	L	M	K	L	E	I	E	T	P	T	H	L	I	D	V	N	G	L	G	L	D	K	I	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	T	D	A	G	G	L	R	I	G	A	L	V	R	N	T	D	L	A	A	H	E	R	V	R	R	D	Y	A	V	L	S	R	A	L	L	A	G	A	S	G	Q	L	R	N	Q	A	T	T	A	G	N	L	L	Q	R	T	R	C	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	F	Y	D	T	N	Q	P	C	N	K	R	L	P	G	S	G	C	A	A	L	E	G	F	S	R	Q	H	A	V	V	G	V	S	E	A	C	I	A	T	H	P	S	D	M	A	V	A	M	R	L	L	D	A	V	V	E	T	I	T
Secondary structure
SS confidence
Disorder								?	?	?	?			?	?	?	?																?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	E	G	K	T	R	S	I	T	L	A	D	F	Y	H	P	P	G	K	T	P	H	I	E	T	A	L	L	P	G	E	L	I	V	A	V	T	L	P	P	P	L	G	G	K	H	I	Y	R	K	V	R	D	R	A	S	Y	A	F	A
Secondary structure
SS confidence
Disorder		?																			?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	V	S	V	A	A	I	I	Q	P	D	G	S	G	R	V	A	L	G	G	V	A	H	K	P	W	R	I	E	A	A	D	A	Q	L	S	Q	G	A	Q	A	V	Y	D	T	L	F	A	S	A	H	P	T	A	E	N	T	F	K	L
Secondary structure
SS confidence
Disorder																																																	?				?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.
Sequence		L	L	A	K	R	T	L	A	S	V	L	A	E	A	R	A	Q	A
Secondary structure
SS confidence
Disorder																		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1rm6 chain E Region: 1 - 315 Aligned: 303 Modelled: 312 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: E: PDB Molecule:4-hydroxybenzoyl-coa reductase beta subunit; PDBTitle: structure of 4-hydroxybenzoyl-coa reductase from thauera2 aromatica Phyre2 PDB 3hrd chain C Region: 1 - 317 Aligned: 271 Modelled: 274 Confidence: 100.0% Identity: 26% PDB header:oxidoreductase Chain: C: PDB Molecule:nicotinate dehydrogenase fad-subunit; PDBTitle: crystal structure of nicotinate dehydrogenase Phyre2 PDB 1n62 chain C Region: 1 - 318 Aligned: 269 Modelled: 275 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: C: PDB Molecule:carbon monoxide dehydrogenase medium chain; PDBTitle: crystal structure of the mo,cu-co dehydrogenase (codh), n-2 butylisocyanide-bound state Phyre2 PDB 1t3q chain F Region: 1 - 318 Aligned: 267 Modelled: 275 Confidence: 100.0% Identity: 29% PDB header:oxidoreductase Chain: F: PDB Molecule:quinoline 2-oxidoreductase medium subunit; PDBTitle: crystal structure of quinoline 2-oxidoreductase from pseudomonas2 putida 86 Phyre2 PDB 1ffu chain F Region: 1 - 318 Aligned: 269 Modelled: 275 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: F: PDB Molecule:cutm, flavoprotein of carbon monoxide PDBTitle: carbon monoxide dehydrogenase from hydrogenophaga2 pseudoflava which lacks the mo-pyranopterin moiety of the3 molybdenum cofactor Phyre2 PDB 2w3r chain G Region: 2 - 318 Aligned: 265 Modelled: 274 Confidence: 100.0% Identity: 25% PDB header:oxidoreductase Chain: G: PDB Molecule:xanthine dehydrogenase; PDBTitle: crystal structure of xanthine dehydrogenase (desulfo form)2 from rhodobacter capsulatus in complex with hypoxanthine Phyre2 PDB 3etr chain M Region: 2 - 318 Aligned: 268 Modelled: 274 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: M: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of xanthine oxidase in complex with2 lumazine Phyre2 PDB 3b9j chain J Region: 2 - 318 Aligned: 268 Modelled: 274 Confidence: 100.0% Identity: 17% PDB header:oxidoreductase Chain: J: PDB Molecule:xanthine oxidase; PDBTitle: structure of xanthine oxidase with 2-hydroxy-6-methylpurine Phyre2 PDB 1wyg chain A Region: 5 - 317 Aligned: 264 Modelled: 270 Confidence: 100.0% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of a rat xanthine dehydrogenase triple mutant2 (c535a, c992r and c1324s) Phyre2 PDB 1rm6 chain B domain 2 Region: 1 - 221 Aligned: 211 Modelled: 218 Confidence: 100.0% Identity: 31% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1t3q chain C domain 2 Region: 1 - 222 Aligned: 173 Modelled: 179 Confidence: 100.0% Identity: 32% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1n62 chain C domain 2 Region: 1 - 222 Aligned: 173 Modelled: 179 Confidence: 100.0% Identity: 32% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1ffv chain C domain 2 Region: 1 - 223 Aligned: 174 Modelled: 180 Confidence: 100.0% Identity: 29% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1v97 chain A domain 6 Region: 2 - 223 Aligned: 173 Modelled: 179 Confidence: 100.0% Identity: 17% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 3b9j chain B domain 2 Region: 2 - 223 Aligned: 173 Modelled: 179 Confidence: 100.0% Identity: 17% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1jro chain A domain 4 Region: 6 - 222 Aligned: 166 Modelled: 174 Confidence: 100.0% Identity: 27% Fold: FAD-binding/transporter-associated domain-like Superfamily: FAD-binding/transporter-associated domain-like Family: CO dehydrogenase flavoprotein N-terminal domain-like Phyre2 PDB 1jro chain A domain 3 Region: 226 - 318 Aligned: 93 Modelled: 93 Confidence: 99.7% Identity: 20% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 PDB 1n62 chain C domain 1 Region: 223 - 318 Aligned: 95 Modelled: 96 Confidence: 99.7% Identity: 21% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 PDB 1t3q chain C domain 1 Region: 226 - 318 Aligned: 92 Modelled: 93 Confidence: 99.7% Identity: 26% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 PDB 1ffv chain C domain 1 Region: 223 - 318 Aligned: 95 Modelled: 96 Confidence: 99.6% Identity: 27% Fold: CO dehydrogenase flavoprotein C-domain-like Superfamily: CO dehydrogenase flavoprotein C-terminal domain-like Family: CO dehydrogenase flavoprotein C-terminal domain-like Phyre2 1 c1rm6E_ 2 c3hrdC_ 3 c1n62C_ 4 c1t3qF_ 5 c1ffuF_ 6 c2w3rG_ 7 c3etrM_ 8 c3b9jJ_ 9 c1wygA_ 10 d1rm6b2 11 d1t3qc2 12 d1n62c2 13 d1ffvc2 14 d1v97a6 15 d3b9jb2 16 d1jroa4 17 d1jroa3 18 d1n62c1 19 d1t3qc1 20 d1ffvc1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1rm6E_ 100.0 29 PDB header:oxidoreductase Chain: E: PDB Molecule:4-hydroxybenzoyl-coa reductase beta subunit; PDBTitle: structure of 4-hydroxybenzoyl-coa reductase from thauera2 aromatica 2 c3hrdC_ 100.0 26 PDB header:oxidoreductase Chain: C: PDB Molecule:nicotinate dehydrogenase fad-subunit; PDBTitle: crystal structure of nicotinate dehydrogenase 3 c1n62C_ 100.0 28 PDB header:oxidoreductase Chain: C: PDB Molecule:carbon monoxide dehydrogenase medium chain; PDBTitle: crystal structure of the mo,cu-co dehydrogenase (codh), n-2 butylisocyanide-bound state 4 c1t3qF_ 100.0 29 PDB header:oxidoreductase Chain: F: PDB Molecule:quinoline 2-oxidoreductase medium subunit; PDBTitle: crystal structure of quinoline 2-oxidoreductase from pseudomonas2 putida 86 5 c1ffuF_ 100.0 28 PDB header:hydrolase Chain: F: PDB Molecule:cutm, flavoprotein of carbon monoxide PDBTitle: carbon monoxide dehydrogenase from hydrogenophaga2 pseudoflava which lacks the mo-pyranopterin moiety of the3 molybdenum cofactor 6 c2w3rG_ 100.0 25 PDB header:oxidoreductase Chain: G: PDB Molecule:xanthine dehydrogenase; PDBTitle: crystal structure of xanthine dehydrogenase (desulfo form)2 from rhodobacter capsulatus in complex with hypoxanthine 7 c3etrM_ 100.0 17 PDB header:oxidoreductase Chain: M: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of xanthine oxidase in complex with2 lumazine 8 c3b9jJ_ 100.0 17 PDB header:oxidoreductase Chain: J: PDB Molecule:xanthine oxidase; PDBTitle: structure of xanthine oxidase with 2-hydroxy-6-methylpurine 9 c1wygA_ 100.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:xanthine dehydrogenase/oxidase; PDBTitle: crystal structure of a rat xanthine dehydrogenase triple mutant2 (c535a, c992r and c1324s) 10 d1rm6b2 100.0 31 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 11 d1t3qc2 100.0 32 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 12 d1n62c2 100.0 32 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 13 d1ffvc2 100.0 29 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 14 d1v97a6 100.0 17 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 15 d3b9jb2 100.0 17 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 16 d1jroa4 100.0 27 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CO dehydrogenase flavoprotein N-terminal domain-like 17 d1jroa3 99.7 20 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 18 d1n62c1 99.7 21 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 19 d1t3qc1 99.7 26 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 20 d1ffvc1 99.6 27 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 21 d1v97a4 not modelled 99.6 14 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 22 d1rm6b1 not modelled 99.6 27 Fold:CO dehydrogenase flavoprotein C-domain-like Superfamily:CO dehydrogenase flavoprotein C-terminal domain-like Family:CO dehydrogenase flavoprotein C-terminal domain-like 23 c1mbbA_ not modelled 97.9 22 PDB header:oxidoreductase Chain: A: PDB Molecule:uridine diphospho-n-acetylenolpyruvylglucosamine PDBTitle: oxidoreductase 24 c3i99A_ not modelled 97.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvoylglucosamine reductase; PDBTitle: the crystal structure of the udp-n-acetylenolpyruvoylglucosamine2 reductase from the vibrio cholerae o1 biovar tor 25 d1hska1 not modelled 97.7 14 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain 26 c1hskA_ not modelled 97.4 12 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvoylglucosamine reductase; PDBTitle: crystal structure of s. aureus murb 27 c2vfvA_ not modelled 97.4 23 PDB header:oxidoreductase Chain: A: PDB Molecule:xylitol oxidase; PDBTitle: alditol oxidase from streptomyces coelicolor a3(2): complex2 with sulphite 28 c2wdwB_ not modelled 97.3 13 PDB header:oxidoreductase Chain: B: PDB Molecule:putative hexose oxidase; PDBTitle: the native crystal structure of the primary hexose oxidase (2 dbv29) in antibiotic a40926 biosynthesis 29 d1uxya1 not modelled 97.2 22 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase (MurB), N-terminal domain 30 c2gquA_ not modelled 97.1 25 PDB header:oxidoreductase Chain: A: PDB Molecule:udp-n-acetylenolpyruvylglucosamine reductase; PDBTitle: crystal structure of udp-n-acetylenolpyruvylglucosamine2 reductase (murb) from thermus caldophilus 31 c3bw7A_ not modelled 97.0 18 PDB header:oxidoreductase Chain: A: PDB Molecule:cytokinin dehydrogenase 1; PDBTitle: maize cytokinin oxidase/dehydrogenase complexed with the allenic2 cytokinin analog ha-1 32 c2ipiD_ not modelled 96.9 14 PDB header:oxidoreductase Chain: D: PDB Molecule:aclacinomycin oxidoreductase (aknox); PDBTitle: crystal structure of aclacinomycin oxidoreductase 33 c2y3rC_ not modelled 96.9 14 PDB header:oxidoreductase Chain: C: PDB Molecule:taml; PDBTitle: structure of the tirandamycin-bound fad-dependent2 tirandamycin oxidase taml in p21 space group 34 d1f0xa2 not modelled 96.9 20 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 35 c2uuvC_ not modelled 96.8 14 PDB header:transferase Chain: C: PDB Molecule:alkyldihydroxyacetonephosphate synthase; PDBTitle: alkyldihydroxyacetonephosphate synthase in p1 36 c3popD_ not modelled 96.8 18 PDB header:oxidoreductase Chain: D: PDB Molecule:gilr oxidase; PDBTitle: the crystal structure of gilr, an oxidoreductase that catalyzes the2 terminal step of gilvocarcin biosynthesis 37 c3d2hA_ not modelled 96.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:berberine bridge-forming enzyme; PDBTitle: structure of berberine bridge enzyme from eschscholzia californica,2 monoclinic crystal form 38 c1f0xA_ not modelled 96.5 17 PDB header:oxidoreductase Chain: A: PDB Molecule:d-lactate dehydrogenase; PDBTitle: crystal structure of d-lactate dehydrogenase, a peripheral2 membrane respiratory enzyme. 39 c1zr6A_ not modelled 96.5 12 PDB header:oxidoreductase Chain: A: PDB Molecule:glucooligosaccharide oxidase; PDBTitle: the crystal structure of an acremonium strictum glucooligosaccharide2 oxidase reveals a novel flavinylation 40 c2bvfA_ not modelled 96.5 21 PDB header:oxidase Chain: A: PDB Molecule:6-hydroxy-d-nicotine oxidase; PDBTitle: crystal structure of 6-hydoxy-d-nicotine oxidase from2 arthrobacter nicotinovorans. crystal form 3 (p1) 41 c3fwaA_ not modelled 96.5 13 PDB header:flavoprotein Chain: A: PDB Molecule:reticuline oxidase; PDBTitle: structure of berberine bridge enzyme, c166a variant in complex with2 (s)-reticuline 42 c1wveB_ not modelled 96.2 9 PDB header:oxidoreductase Chain: B: PDB Molecule:4-cresol dehydrogenase [hydroxylating] PDBTitle: p-cresol methylhydroxylase: alteration of the structure of2 the flavoprotein subunit upon its binding to the3 cytochrome subunit 43 c2exrA_ not modelled 95.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:cytokinin dehydrogenase 7; PDBTitle: x-ray structure of cytokinin oxidase/dehydrogenase (ckx)2 from arabidopsis thaliana at5g21482 44 d1wvfa2 not modelled 95.7 8 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 45 c3js8A_ not modelled 95.7 13 PDB header:oxidoreductase Chain: A: PDB Molecule:cholesterol oxidase; PDBTitle: solvent-stable cholesterol oxidase 46 c1i19B_ not modelled 95.3 14 PDB header:oxidoreductase Chain: B: PDB Molecule:cholesterol oxidase; PDBTitle: crystal structure of cholesterol oxidase from b.sterolicum 47 d2i0ka2 not modelled 95.2 15 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 48 c3pm9A_ not modelled 94.8 13 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative dehydrogenase (rpa1076) from2 rhodopseudomonas palustris cga009 at 2.57 a resolution 49 d1e8ga2 not modelled 94.2 13 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 50 c1ahuB_ not modelled 93.9 11 PDB header:flavoenzyme Chain: B: PDB Molecule:vanillyl-alcohol oxidase; PDBTitle: structure of the octameric flavoenzyme vanillyl-alcohol2 oxidase in complex with p-cresol 51 d1w1oa2 not modelled 87.8 17 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:FAD-linked oxidases, N-terminal domain 52 c2yvsA_ not modelled 60.3 17 PDB header:oxidoreductase Chain: A: PDB Molecule:glycolate oxidase subunit glce; PDBTitle: crystal structure of glycolate oxidase subunit glce from thermus2 thermophilus hb8 53 d1fmta1 not modelled 30.1 19 Fold:FMT C-terminal domain-like Superfamily:FMT C-terminal domain-like Family:Post formyltransferase domain 54 d1ujpa_ not modelled 27.9 10 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 55 d1oj7a_ not modelled 26.5 12 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 56 c3ix9B_ not modelled 21.4 10 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: crystal structure of streptococcus pneumoniae dihydrofolate2 reductase - sp9 mutant 57 c2blcA_ not modelled 19.5 17 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrofolate reductase-thymidylate synthase; PDBTitle: sp21 double mutant p. vivax dihydrofolate reductase in2 complex with des-chloropyrimethamine 58 d1j3ka_ not modelled 19.1 17 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 59 d1vpaa_ not modelled 17.8 19 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:Cytidylytransferase 60 c1zdrB_ not modelled 16.9 21 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrofolate reductase; PDBTitle: dhfr from bacillus stearothermophilus 61 c3dg8B_ not modelled 16.6 17 PDB header:oxidoreductase, transferase Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump 62 c1cf2Q_ not modelled 15.5 13 PDB header:oxidoreductase Chain: Q: PDB Molecule:protein (glyceraldehyde-3-phosphate PDBTitle: three-dimensional structure of d-glyceraldehyde-3-phosphate2 dehydrogenase from the hyperthermophilic archaeon3 methanothermus fervidus 63 c1b7gO_ not modelled 14.2 10 PDB header:oxidoreductase Chain: O: PDB Molecule:protein (glyceraldehyde 3-phosphate dehydrogenase); PDBTitle: glyceraldehyde 3-phosphate dehydrogenase 64 c2qyaA_ not modelled 14.2 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized conserved protein; PDBTitle: crystal structure of an uncharacterized conserved protein2 from methanopyrus kandleri 65 d1vlja_ not modelled 14.0 18 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 66 d1aoea_ not modelled 13.3 18 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 67 d2ji7a1 not modelled 13.1 17 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 68 c2dyoB_ not modelled 12.5 33 PDB header:protein turnover/protein turnover Chain: B: PDB Molecule:autophagy protein 16; PDBTitle: the crystal structure of saccharomyces cerevisiae atg5-2 atg16(1-57) complex 69 c3imkA_ not modelled 11.8 21 PDB header:metal binding protein Chain: A: PDB Molecule:putative molybdenum carrier protein; PDBTitle: crystal structure of putative molybdenum carrier protein (yp_461806.1)2 from syntrophus aciditrophicus sb at 1.45 a resolution 70 d1ozha1 not modelled 10.8 13 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 71 c2xecD_ not modelled 10.4 17 PDB header:isomerase Chain: D: PDB Molecule:putative maleate isomerase; PDBTitle: nocardia farcinica maleate cis-trans isomerase bound to2 tris 72 d1g97a2 not modelled 10.1 24 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:UDP-glucose pyrophosphorylase 73 c1m6yA_ not modelled 9.9 3 PDB header:transferase Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw; PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah 74 c3tqqA_ not modelled 9.5 25 PDB header:transferase Chain: A: PDB Molecule:methionyl-trna formyltransferase; PDBTitle: structure of the methionyl-trna formyltransferase (fmt) from coxiella2 burnetii 75 c3q0iA_ not modelled 9.5 18 PDB header:transferase Chain: A: PDB Molecule:methionyl-trna formyltransferase; PDBTitle: methionyl-trna formyltransferase from vibrio cholerae 76 d1i1ga2 not modelled 9.5 14 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Lrp/AsnC-like transcriptional regulator C-terminal domain 77 d1uz5a3 not modelled 9.3 19 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 78 d1wp5a_ not modelled 9.3 16 Fold:6-bladed beta-propeller Superfamily:GyrA/ParC C-terminal domain-like Family:GyrA/ParC C-terminal domain-like 79 c3ngwA_ not modelled 9.2 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:molybdopterin-guanine dinucleotide biosynthesis protein a PDBTitle: crystal structure of molybdopterin-guanine dinucleotide biosynthesis2 protein a from archaeoglobus fulgidus, northeast structural genomics3 consortium target gr189 80 d1q6za1 not modelled 9.1 4 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 81 d2djia1 not modelled 9.1 13 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 82 d3dfra_ not modelled 8.9 21 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 83 d1li4a2 not modelled 8.8 18 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:S-adenosylhomocystein hydrolase 84 d2ez9a1 not modelled 8.8 9 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 85 d2dpwa1 not modelled 8.8 19 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:TTHA0179-like 86 d2blna1 not modelled 8.7 13 Fold:FMT C-terminal domain-like Superfamily:FMT C-terminal domain-like Family:Post formyltransferase domain 87 d1ybha1 not modelled 8.1 9 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 88 d1w55a1 not modelled 7.6 9 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:Cytidylytransferase 89 c3gxxB_ not modelled 7.2 13 PDB header:transcription Chain: B: PDB Molecule:transcription elongation factor spt6; PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b 90 c2xwlB_ not modelled 7.2 22 PDB header:transferase Chain: B: PDB Molecule:2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase; PDBTitle: crystal structure of ispd from mycobacterium smegmatis in complex2 with ctp and mg 91 d2oi6a2 not modelled 7.1 17 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:UDP-glucose pyrophosphorylase 92 d2dx7a1 not modelled 7.1 21 Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase 93 c2we9A_ not modelled 7.1 17 PDB header:unknown function Chain: A: PDB Molecule:moba-related protein; PDBTitle: crystal structure of rv0371c from mycobacterium2 tuberculosis h37rv 94 c2yyyB_ not modelled 7.0 10 PDB header:oxidoreductase Chain: B: PDB Molecule:glyceraldehyde-3-phosphate dehydrogenase; PDBTitle: crystal structure of glyceraldehyde-3-phosphate2 dehydrogenase 95 d1tzfa_ not modelled 7.0 21 Fold:Nucleotide-diphospho-sugar transferases Superfamily:Nucleotide-diphospho-sugar transferases Family:Cytidylytransferase 96 d1o94c_ not modelled 7.0 8 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:ETFP subunits 97 c3tq8A_ not modelled 6.7 18 PDB header:oxidoreductase/oxidoreductase inhibitor Chain: A: PDB Molecule:dihydrofolate reductase; PDBTitle: structure of the dihydrofolate reductase (fola) from coxiella burnetii2 in complex with trimethoprim 98 d1jfla2 not modelled 6.6 21 Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase 99 c2yukA_ not modelled 6.6 10 PDB header:transferase Chain: A: PDB Molecule:myeloid/lymphoid or mixed-lineage leukemia PDBTitle: solution structure of the hmg box of human myeloid/lymphoid2 or mixed-lineage leukemia protein 3 homolog

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0